JP7049147B2 - Ophthalmic microscope and function expansion unit - Google Patents

Description

The present invention relates to an ophthalmic microscope such as a fundus camera, a slit lamp, and an ophthalmic surgery microscope having an illumination optical system for illuminating the eye to be inspected and an observation optical system for observing the illuminated eye to be inspected. The ophthalmic microscope of the present invention has an OCT optical system capable of obtaining a tomographic image of the eye to be inspected by optical coherence tomography (abbreviated as "OCT"), and has an OCT optical system and an observation optical system. It is characterized by having a structure that can be independent of and, which can increase the degree of freedom in designing an ophthalmic microscope.
The present invention also relates to a function expansion unit that can be attached to and detached from an ophthalmic microscope and can add an OCT function to an ophthalmic microscope.

An ophthalmic microscope is a medical or examination device capable of illuminating a patient's eye to be inspected with an illumination optical system and magnifying and observing the eye to be inspected by an observation optical system including a lens or the like. Such an ophthalmic microscope has been developed so that a tomographic image of the eye to be inspected can be obtained by having an OCT optical system.

OCT is a technique for constructing an interferometer using a light source having a low coherence (a short coherence distance), thereby obtaining a tomographic image of a living body. Specifically, using a light source with low coherence, this light is divided into two by a beam splitter, and one light (measurement light) is applied to a living tissue to be reflected or scattered, and the other light (reference light). Is reflected by the mirror. The measured light is reflected or scattered at various depths of the living tissue, and innumerable reflected or scattered light is returned. When the measured light returned to the beam splitter and the reflected light of the reference light are merged, only the reflected light or the scattered light of the measured light that has passed the same distance as the reference light is detected by interfering with the reflected light of the reference light. .. Therefore, by adjusting the positions of the beam splitter and the mirror to change the path length of the reference light in various ways, the intensity of the measured light reflected at various depths of the living tissue can be detected. With such an OCT optical system, a tomographic image of a living tissue can be obtained.
By providing this OCT optical system in an ophthalmic microscope, it became possible to obtain tomographic images of the retina, cornea, iris, etc. of the eye, and it became possible to observe not only the surface of the tissue but also the internal state. This can improve the diagnostic accuracy of eye diseases and increase the success rate of ophthalmic surgery.

In an ophthalmic microscope having such an OCT optical system, it is necessary to incorporate the OCT optical system into a microscope having an illumination optical system and an observation optical system so that the light of the OCT optical system can be incident on the eye to be inspected. The method is being developed.
For example, the Galileo type has an observation optical system consisting of an observation optical system for the left eye and an observation optical system for the right eye of the observer, and has one objective lens through which the optical axes of the left and right observation optical systems transmit in common. In an ophthalmic microscope, there is a method in which the light of an OCT light source incident from the side of an objective lens is reflected by a reflecting member directly above the objective lens, transmitted through the objective lens, and incident on the eye to be inspected (Patent Document 1 and). 2nd grade).

More specifically, as shown in FIG. 17 (drawing with reference to FIG. 1 of Patent Document 1), the ophthalmic microscope has an optical axis of the observation optical system for the left eye and an optical axis of the observation optical system for the right eye. The optical axis of the observation optical system consisting of 130, 140, 150, 170, and 180 paired lenses on the left and right, and the optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye are common. It has one transmissive objective lens 110, OCT optical systems 200, 250, 450, 460, 470, and illumination optical systems 310, 320, 330. In the OCT optical system, the output light from the OCT light source 200 is emitted through the optical fiber 250, the direction is controlled by the two scanning mirrors 450 and 460, and then the beam combiner 340 is used from the illumination optical system. It merges with the illumination light, is reflected by the beam splitter 120, and is incident on the eye 1000 to be inspected.

Further, in a Galilean ophthalmic microscope, there is a method in which light from an OCT light source is emitted from the upper part of an objective lens, transmitted through the objective lens, and incident on the eye to be inspected (Patent Document 3).
Further, in a Galilean ophthalmic microscope, there is a method in which the optical path of the OCT optical system is merged substantially coaxially with the optical path of the observation optical system, and is transmitted through an objective lens to be incident on the eye to be inspected (Patent Documents 4 and 5). ).

In all of the above methods, the optical axis of the observation optical system and the optical axis of the OCT optical system commonly pass through one objective lens.

In the Galileo type ophthalmic microscope, as a method in which the optical axis of the OCT optical system does not pass through the objective lens, the light of the OCT light source incident from the side of the objective lens is reflected by a reflecting member directly under the objective lens. There is a method in which an objective lens is not transmitted and is incident on the eye to be inspected (Patent Document 6).
More specifically, as shown in FIG. 18 (drawing with reference to FIG. 2A of Patent Document 6), the light is incident from the side of the objective lens at the lower part of the objective lens 102 through which the optical axis of the observation optical system is transmitted. The light of the OCT light source is reflected by the dichroic mirror 400, and the light of the OCT optical system is incident on the eye to be inspected.
In this method, the optical path of the observation optical system and the optical path of the OCT optical system merge coaxially directly under the objective lens.

In addition, as a method different from the Galilean type ophthalmic microscope, it has two objective lenses corresponding to the left and right observation optical systems, and a stereo angle is provided between the left and right observation optical systems for the greenau type ophthalmology. There is a microscope (Patent Documents 7 and 8). In the Greenough type ophthalmic microscope, since there is no objective lens that transmits the optical axis of the left and right observation optical systems in common, the optical path of the OCT optical system should be incident on the subject without passing through the objective lens. Can be done.
However, in the Greenough type ophthalmic microscope, complicated optical design is required because the left and right observation optical systems are tilted with each other to have a stereo angle.

As a device for observing the eye to be inspected, there is an SLO (Scanning Laser Ophthalmoscope) that irradiates the eye to be inspected with a laser beam and detects the reflected light, but it is a device in which SLO and OCT are combined. Has also been developed (Patent Document 9).

Japanese Unexamined Patent Publication No. 8-66421 Japanese Unexamined Patent Publication No. 2008-264488 Japanese Unexamined Patent Publication No. 2008-268852 Special Table 2010-522555 Gazette Japanese Unexamined Patent Publication No. 2008-264490 U.S. Pat. No. 8,366,271 Japanese Unexamined Patent Publication No. 2016-185177 Japanese Unexamined Patent Publication No. 2016-185178 JP-A-2015-221091

As described above, conventional ophthalmic microscopes equipped with an OCT optical system include a Galileo ophthalmic microscope and a Greenough ophthalmic microscope, but the Greenough ophthalmic microscope requires a complicated optical design. Met.
Further, in the conventional Galileo type ophthalmic microscope, as shown in Patent Documents 1 to 5, the optical axis of the observation optical system and the optical axis of the OCT optical system commonly transmit one objective lens. However, since the observation optical system and the OCT optical system are not independent, the OCT optical system and the observation optical system are influenced by each other, and the degree of freedom in optical design is limited. Met.
In the conventional Galileo type ophthalmic microscope, as shown in Patent Document 6, a method has been developed in which the optical axis of the OCT optical system does not pass through the objective lens, but OCT optics is used between the objective lens and the eye to be inspected. Since the optical member of the system is provided, there is a problem that the degree of freedom in optical design is limited, such as the inability to secure a sufficient distance from the ophthalmologic microscope to the eye to be inspected.

Therefore, in view of the above-mentioned conventional situation, it is an object of the present invention to develop a new type ophthalmic microscope that enhances the degree of freedom in optical design in the Galilean type ophthalmic microscope provided with the OCT optical system.

As a result of diligent research by the inventors of the present application in order to solve the above-mentioned problems, the optical axis of the OCT optical system does not transmit through the objective lens through which the optical axis of the observation optical system is transmitted in the Galileo type ophthalmic microscope. By arranging the optical axis of the optical system and the optical axis of the OCT optical system so as to be non-coaxial, the observation optical system and the OCT optical system become independent, the degree of freedom in optical design is increased, and the OCT optical system is increased. It was found that it is also possible to make the unit detachable. Here, since the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial, the image observed by the observation optical system and the image obtained by the OCT optical system are different from each other. We have found that by providing an SLO optical system that guides a light beam substantially coaxial with the optical axis of the optical system to the eye to be inspected, the portion of the eye to be scanned scanned by the OCT optical system can be observed without deviation, and the present invention has been completed. ..

That is, the present invention provides the following first invention relating to an ophthalmic microscope, the following second invention relating to a function expansion unit, and the following third invention relating to a function expansion set.
(1) The first invention has an illumination optical system for illuminating the eye to be inspected, an observation optical system for the left eye and an observation optical system for the right eye for observing the eye to be inspected illuminated by the illumination optical system. The observation optical system, the objective lens through which the optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye of the observation optical system are transmitted in common, and the eye to be inspected by optical coherence stromography. In an ophthalmic microscope with an OCT optical system that scans the measurement light for inspection.
The optical axis of the OCT optical system does not pass through the objective lens through which the optical axis of the observation optical system is transmitted, and the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial. The observation optical system, the objective lens, and the OCT optical system are arranged.
It further has an SLO optical system that scans visible light, near-infrared rays, or light rays that are infrared rays and guides the eye to be inspected so as to be substantially coaxial with the optical axis of the OCT optical system. The present invention relates to an ophthalmic microscope, characterized in that the portion of the eye to be inspected scanned by the OCT optical system can be observed.
(2) In the first invention, the OCT optical system is
A first optical member that guides the light from the OCT light source in the direction of the first optical axis,
A first reflecting member that guides the light guided in the first optical axis direction in the second optical axis direction substantially orthogonal to the first optical axis direction.
A second optical member that relays the light guided in the second optical axis direction, and the second optical member.
A second reflective member that guides the light relayed by the second optical member in the direction of the third optical axis substantially orthogonal to the second optical axis direction.
It is preferable to have an OCT objective lens arranged on the third optical axis direction and irradiating a predetermined portion of the eye to be inspected with light guided in the third optical axis direction.
(3) In any of the ophthalmic microscopes, it is preferable to have a deflecting optical element that scans the measurement light of the OCT optical system and the light beam of the SLO optical system in common.
(4) In any of the ophthalmic microscopes, the objective lens has a partial shape of a circular lens or a shape in which a notch or a hole is provided in the circular lens.
It is preferable that the optical axis of the OCT optical system passes through a portion where the objective lens does not exist, or a notch or a hole provided in the objective lens.
(5) In the case of (4) above, the circular lens or the lens composed of the circular lens portion is divided into two.
One divided lens is used as the objective lens.
The other divided lens can be used as an OCT objective lens through which the optical axis of the OCT optical system is transmitted.
(6) In any of the ophthalmic microscopes, it is preferable to further have an objective lens position control mechanism for adjusting the position of the OCT objective lens.
(7) In any of the ophthalmic microscopes, it is preferable that the OCT optical system and the SLO optical system are detachably united.
(8) In any of the ophthalmic microscopes, it is preferable to further have a removable front lens on the optical path between the eye to be inspected and the objective lens in order to observe the retina of the eye to be inspected.
(9) The second invention comprises an illumination optical system for illuminating the eye to be inspected, an observation optical system for the left eye and an observation optical system for the right eye for observing the eye to be inspected illuminated by the illumination optical system. A function expansion unit used for an ophthalmologic microscope having an optical system and an objective lens in which the optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye of the observation optical system are transmitted in common. In
A joint part that can be attached to and detached from the ophthalmic microscope,
An OCT optical system that scans the measurement light for inspecting the eye to be inspected by optical coherence tomography, and
It has an SLO optical system that scans visible light, near-infrared, or infrared light to guide the subject to the eye.
When the function expansion unit is attached to the ophthalmic microscope via the joint portion, the optical axis of the OCT optical system does not transmit through the objective lens through which the optical axis of the observation optical system is transmitted, and the observation optical is transmitted. The optical axis of the system and the optical axis of the OCT optical system are non-coaxial, and
A function expansion unit characterized in that the optical axis of the OCT optical system and the optical axis of the SLO optical system are substantially coaxial with each other, and the portion of the eye to be inspected scanned by the OCT optical system can be observed by the SLO optical system. Regarding.
(10) In the function expansion unit of the second invention, the OCT optical system is
A first optical member that guides the light from the OCT light source in the direction of the first optical axis,
A first reflecting member that guides the light guided in the first optical axis direction in the second optical axis direction substantially orthogonal to the first optical axis direction.
A second optical member that relays the light guided in the second optical axis direction, and the second optical member.
A second reflective member that guides the light relayed by the second optical member in the direction of the third optical axis substantially orthogonal to the second optical axis direction.
It is preferable to have an OCT objective lens arranged on the third optical axis direction and irradiating a predetermined portion of the eye to be inspected with light guided in the third optical axis direction.
(11) In any of the function expansion units, it is preferable to have a deflection optical element that scans the measurement light of the OCT optical system and the light rays of the SLO optical system in common.
(12) The third invention provides a function expansion set including the above-mentioned function expansion unit and an interchangeable objective lens for exchanging the objective lens.
(13) In the third invention, the replacement objective lens has a partial shape of a circular lens or a shape in which a notch or a hole is provided in the circular lens.
When the objective lens is replaced with the replacement objective lens and the function expansion unit is attached to the ophthalmologic microscope via the joint portion,
It is preferable that the optical axis of the OCT optical system passes through a portion where the replacement objective lens does not exist, or a notch or a hole provided in the replacement objective lens.

In the ophthalmic microscope of the first invention, the optical axis of the OCT optical system does not pass through the objective lens through which the optical axis of the observation optical system passes, and the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial. It has become. With such a configuration, in the ophthalmic microscope of the present invention, the observation optical system and the OCT optical system are independent. Therefore, in the ophthalmic microscope of the present invention, the observation optical system and the OCT optical system can be optically designed without being influenced by each other. Therefore, the ophthalmic microscope of the present invention has a degree of freedom in optical design. It has the effect of increasing. Further, the ophthalmic microscope of the present invention has an SLO optical system that guides a light beam substantially coaxial with the optical axis of the OCT optical system to the eye to be inspected, whereby the image to be inspected is not deviated from the image obtained by the OCT optical system. It has the effect of being able to observe.
In the function expansion unit of the second invention and the function expansion set of the third invention, the optical axis of the OCT optical system of the function expansion unit does not transmit through the objective lens through which the optical axis of the observation optical system of the ophthalmologic microscope is transmitted. , The optical axis of the observation optical system of the ophthalmic microscope and the optical axis of the OCT optical system of the function expansion unit are non-coaxial. With such a configuration, the OCT optical system of the function expansion unit is independent of the observation optical system of the ophthalmologic microscope, which enables unitization and increases the degree of freedom in optical design. Since the function expansion unit can be attached to and detached from the ophthalmic microscope via the joint portion, the function expansion unit and the function expansion set of the present invention can easily add the OCT function to the ophthalmic microscope. It works. Further, the function expansion unit and the function expansion set of the present invention have an SLO optical system that guides a light beam substantially coaxial with the optical axis of the OCT optical system to the eye to be inspected, thereby forming an image obtained by the OCT optical system. It has the effect of observing the eye to be inspected without any deviation.

It is a drawing which shows typically the structure of the optical system as a side view with respect to the ophthalmologic microscope of 1st Embodiment of this invention. It is a drawing which shows typically the structure of the optical system as a front view of the ophthalmologic microscope of 1st Embodiment of this invention. It is a drawing which shows typically the optical composition of the OCT unit used in the ophthalmologic microscope of 1st Embodiment of this invention. It is a drawing which shows schematically the display part which displays the OCT image and SLO image acquired in the ophthalmologic microscope of 1st Embodiment. It is a drawing which shows typically the shape of the objective lens used in the ophthalmologic microscope of 1st Embodiment of this invention. 5 (A) is a drawing seen from the direction of the optical axis of the objective lens, and FIG. 5 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 5 (A). It is a drawing which shows typically the structure of the optical system as a side view with respect to the ophthalmologic microscope of the 2nd Embodiment of this invention. It is a drawing which shows typically the structure of the optical system as a front view of the ophthalmologic microscope of the 2nd Embodiment of this invention. It is a perspective view of the OCT optical system about the ophthalmologic microscope of the 2nd Embodiment of this invention. It is a top view of the OCT optical system shown in FIG. 8 about the ophthalmologic microscope of the 2nd Embodiment of this invention. It is a side view of the OCT optical system shown in FIG. 8 about the ophthalmologic microscope of the 2nd Embodiment of this invention. It is a front view of the OCT optical system shown in FIG. 8 about the ophthalmologic microscope of the 2nd Embodiment of this invention. It is a drawing which shows typically the shape of the objective lens used in the ophthalmologic microscope of the 3rd Embodiment of this invention. 12 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 12 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 12 (A). It is a drawing which shows typically the shape of the objective lens used in the ophthalmologic microscope of the 4th Embodiment of this invention. 13 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 13 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 13 (A). It is a drawing which shows typically the shape of the objective lens used in the ophthalmologic microscope of the 5th Embodiment of this invention. 14 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 14 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 14 (A). It is a drawing which shows typically the shape of the objective lens used in the ophthalmologic microscope of the 6th Embodiment of this invention. 15 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 15 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 15 (A). It is a drawing which shows typically the shape of the objective lens used in the ophthalmologic microscope of the 7th Embodiment of this invention. 16 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 16 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 16 (A). It is a drawing quoting FIG. 1 of Patent Document 1. FIG. It is a drawing quoting 2A.

1. 1. Ophthalmic microscope 1-1. Outline of the Ophthalmic Microscope of the Present Invention The ophthalmic microscope of the present invention has an illumination optical system for illuminating the eye to be inspected, an observation optical system for the left eye and an observation optical system for the right eye for observing the eye to be inspected illuminated by the illumination optical system. An observation optical system having an observation optical system, an objective lens that transmits the optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye in common, and an eye to be inspected by optical coherence stromography. It relates to an ophthalmic microscope having an OCT optical system for scanning measurement light for inspecting.

In the ophthalmic microscope of the present invention, the optical axis of the OCT optical system does not pass through the objective lens through which the optical axis of the observation optical system is transmitted, and the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial. As described above, the observation optical system, the objective lens, and the OCT optical system are arranged. With such a configuration, in the ophthalmic microscope of the present invention, the observation optical system and the OCT optical system are independent.
Therefore, in the ophthalmic microscope of the present invention, the observation optical system and the OCT optical system can be optically designed without being influenced by each other. Therefore, the ophthalmic microscope of the present invention has a degree of freedom in optical design. It has the effect of increasing.
For example, although not limited to these, in addition to the objective lens of the observation optical system, the OCT optical system is also provided with an objective lens for OCT, and the position of each objective lens is independently controlled for observation optical. An optical design that independently adjusts the focal point of the system and the focal point of the OCT optical system becomes possible. It is also possible to design an optical system in which the OCT optical system is separated from the observation optical system and the OCT optical system is a unit that can be attached to and detached from an ophthalmic microscope. Furthermore, by adding not only one OCT optical system but also a plurality of OCT optical systems to an ophthalmic microscope, it becomes possible to perform an optical design capable of obtaining a three-dimensional tomographic image in more detail.

In this way, when the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial, the center of the image observed by the observation optical system (the part overlapping the optical axis of the observation optical system) and the OCT optical system The center of the image obtained by the above (the portion overlapping the optical axis of the OCT optical system) does not match, and the two images are misaligned. For this reason, it becomes difficult to accurately align the elephant observed by the observation optical system with the image obtained by the OCT optical system.
However, in the ophthalmic microscope of the present invention, an SLO optical system that scans visible light, near-infrared rays, or infrared rays and guides the eye to be examined so as to be substantially coaxial with the optical axis of the OCT optical system is further provided. Have. With this SLO optical system, it is possible to observe the eye to be inspected without deviating from the image obtained by the OCT optical system. For example, the shape of the fundus surface is imaged by the SLO optical system, and this is displayed on a part of the display unit (display), and the tomographic image obtained by the OCT optical system is superimposed or displayed in association with the image. By displaying it in other parts, the observer can accurately grasp which part of the fundus surface the tomographic image corresponds to.

In the present invention, the "ophthalmic microscope" refers to a medical or examination device capable of magnifying and observing an eye to be inspected, including not only for humans but also for animals. The “ophthalmic microscope” includes, but is not limited to, a fundus camera, a slit lamp, an ophthalmic surgery microscope, and the like.

In the present invention, the "illumination optical system" includes an optical element for illuminating the eye to be inspected. The illumination optical system may further include a light source, but may be one that guides natural light to the eye to be inspected.
Further, in the present invention, the "observation optical system" includes an optical element capable of observing the eye to be inspected by the return light reflected and scattered from the eye to be inspected illuminated by the illumination optical system. It is a thing. In the present invention, the observation optical system includes an observation optical system for the left eye and an observation optical system for the right eye, and when parallax is generated in the images obtained by the left and right observation optical systems, binocular vision is used. It is also possible to observe in three dimensions.
Further, the "observation optical system" of the present invention may be one that allows the observer to directly observe the eye to be inspected through an eyepiece or the like, or one that can be observed by receiving light from an image pickup element or the like and forming an image. It may be present, or it may have both functions.

In the present invention, the "OCT optical system" is configured to include an optical element that allows the measurement light of the OCT to pass through. The OCT optical system can further include an OCT light source.
In the present invention, the optical elements used in the "illumination optical system", "observation optical system", and "OCT optical system" are not limited to these, and are, for example, lenses, prisms, mirrors, and optical filters. , A diaphragm, a diffraction grating, a polarizing element and the like can be used.

In the present invention, the "objective lens" refers to a lens provided on the side of the eye to be inspected in an ophthalmic microscope. The front lens (loupe) that is temporarily inserted between the objective lens and the eye to be inspected is not included in the "objective lens" in the present invention.
In the present invention, "the optical axis of the observation optical system and the optical axis of the OCT optical system are" non-coaxial "means that the optical axis of the observation optical system and the OCT are in the region between the objective lens of the ophthalmologic microscope and the eye to be inspected. It means that the directions of the optical axes of the optical system are not the same.
The "objective lens" in the present invention is an objective lens in which the optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye are transmitted in common. As described above, the optical axis of the OCT optical system is transmitted. Does not pass through the objective lens. Further, the optical axis of the illumination optical system may or may not transmit through the objective lens. If the optical axis of the illumination optical system does not pass through the objective lens, an objective lens for illumination may be provided separately.

The "visible light, near-infrared or infrared light" used in the SLO optical system of the ophthalmic microscope of the present invention is any light that includes wavelengths in the visible region, near-infrared region or infrared region. It may be a light ray, but it is preferably a highly directional light ray. More preferably, a laser beam is used.
Further, the SLO optical system is "substantially coaxial with the optical axis of the OCT optical system" if the directions of the optical axes are almost the same in the main region between the objective lens of the ophthalmologic microscope and the eye to be inspected. Well, there may be some deviation. Here, since both the optical path of the OCT optical system and the optical path of the SLO optical system are scanned, the direction of the light fluctuates, but the optical axis of the optical system at the center thereof may be substantially coaxial. Even if there is a slight deviation in the direction of the optical axis, it may be less than 6 °, more preferably less than 4 °, and even more preferably less than 1 °.

The ophthalmic microscope of the present invention has an OCT optical system and an SLO optical system, but from the viewpoint of miniaturizing the apparatus, it is preferable to use a shared optical system as a part of the OCT optical system and the SLO optical system. .. In particular, it is preferable to share a deflection optical element that scans the measurement light of the OCT optical system and the light beam of the SLO optical system.
When a part of the optical system is shared, the optical axis of the OCT optical system and the optical axis of the SLO optical system are substantially coaxial on the side to be inspected, and the measurement light of the OCT optical system and the optical system of the SLO optical system are on the detection system side. It is preferable to separate it from the light beam. In this case, the measurement light and the light beam can be separated by, for example, a dichroic mirror, an optical filter, or the like by utilizing characteristics such as the wavelength and deflection of the light.
When the measurement light of the OCT optical system and the light beam of the SLO optical system are combined and then scanned by the same deflection optical element, the scanning range of the OCT optical system and the scanning range of the SLO optical system are the same. Therefore, the alignment of both images becomes easier.
The deflection optical element shared by the OCT optical system and the SLO optical system may be any optical element capable of scanning light by changing the direction of light. For example, but not limited to these, optical elements having reflecting parts that change direction, such as galvano mirrors, polygon mirrors, rotating mirrors, and MEMS (Micro Electro Mechanical Systems) mirrors, deflection prism scanners, and the like. An optical element that can change the direction of light by an electric field, an acoustic optical effect, or the like can be used, such as an AO element.

1-2. First Embodiment Hereinafter, an example of the embodiment of the present invention will be described in detail with reference to the drawings.
1 to 4 are drawings schematically showing a first embodiment which is an example of an ophthalmic microscope of the present invention. FIG. 1 is a schematic view showing the configuration of the optical system of the ophthalmic microscope of the first embodiment as viewed from the side, and FIG. 2 is a schematic view showing the configuration as viewed from the front. Further, FIG. 3 is a schematic view showing the optical configuration of the OCT unit schematically, FIG. 4 is a schematic view showing a display unit for displaying the acquired OCT image and the SLO image, and FIG. 5 is an objective lens. It is a drawing which shows the shape of.

As shown in FIG. 1, the optical system of the ophthalmic microscope 1 includes an objective lens 2, an illumination optical system 300, an observation optical system 400, an OCT optical system 500, and an SLO optical system 1500.
The objective lens 2, the illumination optical system 300, and the observation optical system 400 are housed in the ophthalmic microscope main body 6. On the other hand, the OCT optical system 500 and the SLO optical system 1500 are housed in the function expansion unit 7. In FIG. 1, the ophthalmic microscope main body 6 and the function expansion unit 7 are shown by alternate long and short dash lines, respectively.
The ophthalmic microscope main body 6 and the function expansion unit 7 are detachably connected by a joint portion (not shown).

As shown in FIG. 1, the illumination optical system 300 illuminates the eye 8 to be inspected via the objective lens 2. The illumination optical system 300 includes an illumination light source 9, an optical fiber 301, an outlet aperture 302, a condenser lens 303, an illumination field aperture 304, a collimating lens 305, and a reflection mirror 306. The optical axis of the illumination optical system 300 is shown by the dotted line O-300 in FIG.

The illumination light source 9 is provided outside the main body 6 of the ophthalmologic microscope. One end of the optical fiber 301 is connected to the illumination light source 9. The other end of the optical fiber is arranged at a position facing the condenser lens 303 inside the main body 6 of the ophthalmologic microscope. The illumination light output from the illumination light source 9 is guided by the optical fiber 301 and incident on the condenser lens 303.
An exit aperture diaphragm 302 is provided at a position facing the exit port (the fiber end on the condenser lens 303 side) of the optical fiber 301. The exit aperture diaphragm 302 acts to block a part of the exit port of the optical fiber 301. When the blocking area by the emission port diaphragm 302 is changed, the emission area of the illumination light is changed. Thereby, the irradiation angle by the illumination light, that is, the angle formed by the incident direction of the illumination light with respect to the eye 8 to be inspected and the optical axis of the objective lens 2 can be changed.

The illumination field diaphragm 304 is provided at a position (position of ×) optically conjugate with the front focal position U0 of the objective lens 2. The collimating lens 305 converts the illumination light that has passed through the illumination field diaphragm 304 into a parallel luminous flux. The reflection mirror 306 reflects the illumination light converted into a parallel luminous flux by the collimating lens 305 toward the objective lens 2. The reflected light passes through the objective lens 2 and irradiates the eye 8 to be inspected.
The illumination light (a part of) irradiated to the eye 8 to be inspected is reflected and scattered by the tissue of the eye to be inspected such as the cornea and the retina. The reflected / scattered return light (also referred to as “observation light”) passes through the objective lens 2 and is incident on the observation optical system 400.

As shown in FIG. 1, the observation optical system 400 includes a variable magnification lens system 401, a beam splitter 402, an imaging lens 403, an image erecting prism 404, an eye width adjusting prism 405, a field diaphragm 406, and an eyepiece lens 407. It is configured to include. The optical axis of the observation optical system 400 is shown by the dotted line O-400 in FIG.
The observation optical system 400 is used for observing the eye 8 illuminated by the illumination optical system 300 through the objective lens 2.

As shown in FIG. 1, the OCT optical system 500 includes an OCT unit 10, an optical fiber 501, a collimating lens 502, an illumination field aperture 509, a dichroic mirror 1501, an optical scanner 503a, 503b, a relay optical system 504, and a first lens group. It includes a 505, a reflection mirror 508, a second lens group 506, and an OCT objective lens 507.
The optical axis of the OCT optical system 500 is shown by the dotted line O-500 in FIG.
As shown in FIG. 1, in the first embodiment, the optical axis O-500 of the OCT optical system does not pass through the objective lens 2, and the optical axis O-400 of the observation optical system and the OCT optical system The optical axis O-500 is non-coaxial, which makes the OCT optical system and the observation optical system independent.

The OCT unit 10 divides the light from the OCT light source having low coherence (short coherence distance) into the measurement light and the reference light. The measurement light is guided by the OCT optical system 500 and irradiates the eye 8 to be inspected, is reflected and scattered in the tissue of the eye to be inspected, and is guided to the OCT unit 10 as return light. The OCT unit 10 detects the interference between the return light of the measurement light and the reference light. This makes it possible to obtain a tomographic image of the tissue of the eye to be inspected.

As shown in FIG. 1, the OCT unit 10 is provided outside the function expansion unit 7, but one end of the optical fiber 501 is connected to the OCT unit 10 so as to be connected to the function expansion unit 7. The measurement light generated by the OCT unit 10 is emitted from the other end of the optical fiber 501. The emitted measurement light is a collimating lens 502, an illumination field aperture 509, a dichroic mirror 1501, an optical scanner 503a, 503b, a relay optical system 504, a first lens group 505, a reflection mirror 508, a second lens group 506, and an objective lens for OCT. The return light of the measurement light irradiated to the subject 8 via 507 or the like and reflected / scattered by the tissue of the subject 8 travels in the same path in the opposite direction and is incident on the other end of the optical fiber 501.

When observing the retina of the fundus, the anterior lens 14 is inserted onto the optical axes O-300, O-400, and O-500 in front of the eye to be inspected by a moving means (not shown). In this case, the anterior focal position U0 of the objective lens 2 is conjugate with the retina 8a of the fundus.
When observing the anterior segment of the cornea, iris, etc., the anterior lens is detached from the front of the eye to be inspected, and the anterior focal position U0 is aligned with the anterior segment.

As shown in FIG. 1, the collimating lens 502 converts the measurement light emitted from the other end of the optical fiber 501 into a parallel light flux. The collimating lens 502 and the other end of the optical fiber 501 are configured to be relatively movable along the optical axis of the measurement light. In the first embodiment, the collimating lens 502 is configured to be movable, but the other end of the optical fiber 501 may be configured to be movable along the optical axis of the measurement light.
The illumination field diaphragm 509 is conjugate with the front focal position U0 of the objective lens 2.
The dichroic mirror 1501 is composed of a reflective member that transmits the measurement light of the OCT optical system 500 without reflecting it.

The optical scanners 503a and 503b in the OCT optical system are deflection optical elements that two-dimensionally deflect the measurement light converted into a parallel luminous flux by the collimating lens 502. The optical scanner includes a first scanner 503a having a deflection plane rotatable about the first axis and a second scanner 503b having a deflection plane rotatable about a second axis orthogonal to the first axis. It is a galvano mirror. A relay optical system 504 is provided between the first scanner 503a and the second scanner 503b. When the distance between the first scanner 503a and the second scanner 503b is shortened, the relay optical system 504 may not be provided.

The first lens group 505 is configured to include one or more lenses. The second lens group 506 is also configured to include one or more lenses. The reflection mirror 508 between the first lens group 505 and the second lens group 506 turns the light toward the eye 8 to be inspected.
Further, an OCT objective lens 507 is provided on the side in contact with the eye 8 to be inspected.
The OCT objective lens is configured to be movable along the optical axis, and the focus of the OCT optical system can be adjusted by controlling the position of the OCT objective lens. This makes it possible to adjust the focal point of the OCT optical system to a position different from the focal point of the observation optical system.

As described above, in the ophthalmic microscope of the first embodiment, the optical axis O-500 of the OCT optical system does not pass through the objective lens 2, and the optical axis O-400 of the observation optical system and the light of the OCT optical system Since the axis O-500 is non-coaxial, the observation optical system and the OCT optical system are independent.
Therefore, in the ophthalmologic microscope of the first embodiment, the observation optical system and the OCT optical system can be controlled independently, and the OCT optical system can be attached to and detached from the ophthalmic microscope. It is also possible to do.

As shown in FIG. 1, the ophthalmic microscope 1 of the present invention further has an SLO optical system 1500. The SLO optical system 1500 includes an SLO light source 16, an optical fiber 1502, a collimating lens 1503, an illumination field aperture 1504, a dichroic mirror 1501, a half mirror 1505, an optical aperture 1506, a condenser lens 1507, a reflected light detector 1508, and an image creation unit 1509. Is configured to include.
Although the SLO light source 16 is provided outside the function expansion unit 7, one end of the optical fiber 1502 is connected to the SLO light source 16 so as to be connected to the function expansion unit 7. The light rays generated by the SLO light source 16 are emitted from the other end of the optical fiber 1502. The emitted light beam passes through the collimating lens 1503 and the illumination field aperture 1504, is reflected by the half mirror 1505, is further reflected by the dichroic mirror 1501, and merges coaxially with the measurement light of the OCT optical system 500.

As shown in FIG. 1, the combined light rays of the SLO optical system 1500 are two-dimensionally scanned by the optical scanners 503a and 503b in the same manner as the measurement light of the OCT optical system 500. By using the optical scanners 503a and 503b, which require a complicated mechanism, in common for the OCT optical system 500 and the SLO optical system 1500, the function expansion unit 7 can be miniaturized and reduced in cost.
In the ophthalmic microscope of the present invention, it is also possible to provide separate optical scanners for the OCT optical system and the SLO optical system, and to scan the OCT optical system and the SLO optical system independently. In this case, it is possible to scan different parts of the observed surface at the same time.
The light rays of the SLO optical system 1500 scanned by the optical scanners 503a and 503b pass through the relay optical system 504, the first lens group 505, the reflection mirror 508, the second lens group 506, the OCT objective lens 507, and the like. 8 is irradiated. Here, the optical axis O-500 of the SLO optical system guided to the eye 8 to be inspected is coaxial with the optical axis O-500 of the OCT optical system. Then, the return light of the light rays reflected / scattered by the tissue of the eye 8 to be inspected travels in the same path in the opposite direction, is reflected by the dichroic mirror 1501, passes through the half mirror 1505, has an optical aperture 1506, and a condenser lens 1507. Is detected by the reflected light detector 1508. The detected signal is converted into an image by the image creation unit 1509.

As shown in FIG. 1, the dichroic mirror 1501 transmits the measurement light of the OCT optical system 500 and reflects the light rays of the SLO optical system 1500. As a result, the measurement light of the OCT optical system 500 and the light rays of the SLO optical system 1500 can be merged and separated.
The half mirror 1505 reflects a part of the light rays of the SLO optical system 1500 and transmits a part of the light rays. The half mirror 1505 can separate the light source side and the light receiving side of the SLO optical system 1500.
The optical aperture 1506 is conjugated with the front focal position U0 of the objective lens 2, and the condenser lens 1507 collects the light rays reflected and scattered by the eye 8 to be inspected.

The reflected light detector 1508 has a photodetector element that detects weak light rays reflected / scattered by the eye 8 to be inspected, and is composed of, for example, an APD (Avalanche photodiode) or a photomultiplier tube. The detection signal from the reflected light detector 1508 is sent to the image creation unit 1509. The light rays from the SLO light source 16 are irradiated to the subject 8 while being scanned by the optical scanners 503a and 503b, and the light rays reflected / scattered by the subject 8 are detected by the reflected light detector 1508, whereby the scan data of the subject 8 is detected. Is obtained. The image creation unit 1509 creates an image of the eye 8 to be inspected based on the scan data. This image is sent to a display so that the morphology of the tissue of the eye to be examined can be observed.
It is also possible to track the movement of the test site during OCT scanning based on the signal or image obtained by SLO. If the subject's eye moves during OCT scanning due to fixative tremor or surgical operation of the subject's eye, the tomographic image obtained by OCT will shift, but the movement of the fundus will be based on the signal or image obtained by SLO. By detecting and scanning the OCT optical system according to the movement of the fundus, it is possible to obtain an OCT tomographic image without deviation.

The ophthalmic microscope of the first embodiment will be described in more detail with reference to the drawings.
FIG. 2 is a schematic view showing the configuration of the optical system of the ophthalmic microscope of the first embodiment as viewed from the front.
As shown in FIG. 2, the observation optical system is divided into an observation optical system 400L for the left eye of the observer and an observation optical system 400R for the right eye, each of which has an observation optical path. The optical axes of the left and right observation optical systems are shown by dotted lines O-400L and O-400R in FIG. 2, respectively.

As shown in FIG. 2, the left and right observation optical systems 400L and 400R have a variable magnification lens system 401, an imaging lens 403, an image erecting prism 404, an eye width adjustment prism 405, a field diaphragm 406, and an eyepiece, respectively. It is configured to include 407. The beam splitter 402 is included only in the observation optical system 400R for the right eye.
The variable magnification lens system 401 includes a plurality of zoom lenses 401a, 401b, and 401c. The zoom lenses 401a, 401b, and 401c can be moved along the optical axes O-400L and O-400R of the left and right observation optical systems by a scaling mechanism (not shown). As a result, the magnifying power when observing or photographing the eye 8 to be inspected 8 is changed.

As shown in FIG. 2, the beam splitter 402 of the observation optical system 400R for the right eye separates a part of the observation light guided along the observation optical system for the right eye from the eye 8 to be photographed. Lead to the system. The photographing optical system includes an imaging lens 1101, a reflection mirror 1102, and a television camera 1103.
The television camera 1103 includes an image pickup device 1103a. The image pickup device 1103a is composed of, for example, a CCD (Charge Coupled Devices) image sensor, a CMOS (Complementary Metal Oxide Semiconductor) image sensor, or the like. As the image pickup element 1103a, one having a two-dimensional light receiving surface (area sensor) is used.
The light receiving surface of the image pickup device 1103a is arranged at a position optically conjugate with the front focal position U0 of the objective lens 2.
The beam splitter and the photographing optical system may be in both the left and right observation optical systems. A three-dimensional image can be obtained by acquiring an image having a parallax with each of the left and right image sensors.
The camera image can be used not only to acquire an image of the observation site but also to track the OCT observation site based on the acquired signal or image. It is possible to correct the fixative tremor of the test site during scanning by OCT and the deviation of the observation site due to the surgical operation.

The image upright prism 404 converts an inverted image into an upright image. The eye width adjusting prism 405 is an optical element for adjusting the distance between the left and right observation optical paths according to the eye width (distance between the left eye and the right eye) of the observer. The field diaphragm 406 blocks the peripheral region in the cross section of the observation light and limits the field of view of the observer. The field diaphragm 406 is provided at a position (position ×) conjugate to the front focal position U0 of the objective lens 2.
The observation optical systems 400L and 400R may be configured to include a stereo variator configured to be removable from the optical path of the observation optical system. The stereo variator is an optical axis position changing element for changing the relative positions of the optical axes O-400L and O-400R of the left and right observation optical systems guided by the left and right variable magnification lens systems 401, respectively. The stereo variator is retracted to, for example, a retracted position provided on the observer side with respect to the observation optical path.

In the ophthalmic microscope of the first embodiment, in addition to the observation optical system used by the main observer, a sub-observation optical system 400S for use by the assistant observer is provided.
As shown in FIG. 2, the sub-observation optical system 400S transfers the return light (observation light) reflected and scattered by the subject 8 illuminated by the illumination optical system to the assistant eyepiece via the objective lens 2. Lead to 411. The optical axis of the sub-observation optical system is shown by the dotted line O-400S in FIG.
The sub-observation optical system 400S is also provided with a pair of left and right optical systems, which enables stereoscopic observation by binoculars.

As shown in FIG. 2, the sub-observation optical system 400S includes a prism 408, a reflection mirror 410, and an assistant eyepiece 411. In the first embodiment, an imaging lens 409 is further arranged between the prism 408 and the reflection mirror 410. The observation light from the eye 8 to be inspected passes through the objective lens 2 and is reflected by the reflecting surface 408a of the prism 408. The observation light reflected by the reflection surface 408a passes through the imaging lens 409, is reflected by the reflection mirror 410, and is guided to the assistant eyepiece 411.
The observation optical systems 400L and 400R and the sub-observation optical system 400S are housed in the ophthalmic microscope main body 6.

When observing the retina of the fundus, the anterior lens 14 is inserted onto the optical axes O-400L, O-400R, and O-400S in front of the eye to be inspected by a moving means (not shown). In this case, the anterior focal position U0 of the objective lens 2 is conjugate with the retina 8a of the fundus.
When observing the anterior segment of the cornea, iris, etc., the anterior lens is detached from the front of the eye to be inspected, and the anterior focal position U0 is aligned with the anterior segment for observation.

FIG. 3 is a drawing schematically showing an optical configuration of the OCT unit 10 used in the ophthalmic microscope of the first embodiment.
The OCT may be an OCT of another method such as an OCT of a spectral domain type in addition to the OCT of the Fourier domain type exemplified below.
As shown in FIG. 3, the OCT unit 10 divides the light emitted from the OCT light source unit 1001 into the measurement light LS and the reference light LR, and detects the interference between the measurement light LS and the reference light LR that have passed through another optical path. It constitutes an interferometer.
The OCT light source unit 1001 is configured to include a wavelength scanning type (wavelength sweep type) light source capable of scanning (sweeping) the wavelength of emitted light, similarly to a general swept source type OCT device. The OCT light source unit 1001 temporally changes the output wavelength at a near-infrared wavelength that cannot be visually recognized by the human eye. The light output from the OCT light source unit 1001 is indicated by reference numeral L0.

The light L0 output from the OCT light source unit 1001 is guided to the polarization controller 1003 by the optical fiber 1002, and its polarization state is adjusted. The polarization controller 1003 adjusts the polarization state of the light L0 guided in the optical fiber 1002 by, for example, applying an external stress to the looped optical fiber 1002.
The light L0 whose polarization state is adjusted by the polarization controller 1003 is guided by the optical fiber 1004 to the fiber coupler 1005 and divided into the measurement light LS and the reference light LR.

As shown in FIG. 3, the reference light LR is guided to the collimator 1007 by the optical fiber 1006 and becomes a parallel light flux. The reference light LR that has become a parallel luminous flux is guided to the corner cube 1010 via the optical path length correction member 1008 and the dispersion compensation member 1009. The optical path length correction member 1008 acts as a delay means for matching the optical path length (optical distance) of the reference light LR and the measurement light LS. The dispersion compensating member 1009 acts as a dispersion compensating means for matching the dispersion characteristics of the reference light LR and the measurement light LS.
The corner cube 1010 turns back the traveling direction of the reference light LR, which has become a parallel luminous flux by the collimator 1007, in the opposite direction. The optical path of the reference light LR incident on the corner cube 1010 and the optical path of the reference light LR emitted from the corner cube 1010 are parallel to each other. Further, the corner cube 1010 is movable in the direction along the incident optical path and the emitted optical path of the reference light LR. This movement changes the length of the optical path (reference optical path) of the reference light LR.

As shown in FIG. 3, the reference light LR via the corner cube 1010 passes through the dispersion compensating member 1009 and the optical path length correction member 1008, is converted from the parallel light beam to the focused light beam by the collimator 1011 and is incident on the optical fiber 1012. Then, the polarization state of the reference light LR is adjusted by being guided by the polarization controller 1013.
The polarization controller 1013 has, for example, the same configuration as the polarization controller 1003. The reference light LR whose polarization state has been adjusted by the polarization controller 1013 is guided to the attenuator 1015 by the optical fiber 1014, and the amount of light is adjusted under the control of the arithmetic control unit 12. The reference optical LR whose light amount is adjusted by the attenuator 1015 is guided to the fiber coupler 1017 by the optical fiber 1016.

As can be seen from FIGS. 1 and 3, the measurement light LS generated by the fiber coupler 1005 is guided to the collimating lens 502 by the optical fiber 501. As shown in FIG. 1, the measurement light incident on the collimating lens 502 includes an illumination field diaphragm 509, optical scanners 503a and 503b, a relay optical system 504, a first lens group 505, a reflection mirror 508, and a second lens group 506. And the eye 8 to be inspected is irradiated via the objective lens 507 for OCT. The measurement light is reflected and scattered at various depth positions of the eye 8 to be inspected. The backscattered light of the light measured by the eye 8 travels in the same path as the outward path in the opposite direction, is guided to the fiber coupler 1005, and is guided to the fiber coupler 1017 via the optical fiber 1018 as shown in FIG. To reach.

The fiber coupler 1017 combines (interferes with) the measured light LS incident via the optical fiber 1018 and the reference light LR incident via the optical fiber 1016 to generate interference light. The fiber coupler 1017 generates a pair of interference light LCs by branching the interference light between the measurement light LS and the reference light LR at a predetermined branching ratio (for example, 50:50). The pair of interference light LCs emitted from the fiber coupler 1017 are guided to the detector 1021 by the two optical fibers 1019 and 1020, respectively.

The detector 1021 is, for example, a balanced photodiode (hereinafter referred to as "BPD") having a pair of photodetectors for detecting each pair of interference light LCs and outputting the difference between the detection results. The detector 1021 sends the detection result (detection signal) to the arithmetic control unit 12. The arithmetic control unit 12 forms a cross-sectional image by, for example, performing a Fourier transform or the like on the spectral distribution based on the detection result obtained by the detector 1021 for each series of wavelength scans (for each A line). The arithmetic control unit 12 causes the display unit 13 to display the formed image.

In this embodiment, a Michaelson type interferometer is adopted, but for example, any type of interferometer such as a Mach-Zehnder type can be appropriately adopted.

FIG. 4 is a schematic diagram showing a display unit that displays an OCT image and an SLO image acquired by the ophthalmologic microscope of the first embodiment.
As shown in FIG. 4, the display unit 13 has a display screen 1301. The display screen 1301 is provided with six image display units 1302 to 1307. These image display units include a first vertical cross-sectional image display unit 1302, a cross-sectional image display unit 1303, a processed image display unit 1304, a front image display unit 1305, a second vertical cross-sectional image display unit 1306, and an operation. The guide image display unit 1307.
An image of the fundus surface acquired by the SLO optical system is displayed on the front image display unit 1305, and the first vertical cross-sectional image display unit 1302, the cross-sectional image display unit 1303, and the second vertical cross-sectional image display unit 1306 are displayed. Displays a tomographic image of the fundus of the eye acquired by the OCT optical system. The processed image display unit 1304 has an image (processed image) obtained by performing a predetermined processing process on an image displayed on another image display unit, for example, angiography (angiography) or projection (projection). , Fundar tomographic image), images for detecting lesions such as diabetic retinopathy are displayed. In FIG. 4, the processed image display unit 1304 displays the image of the fundus surface obtained by the SLO optical system in which the lesion portion is colored. Here, the location of the lesion is identified by image analysis of the tomographic image obtained by OCT.

As shown in FIG. 4, in the front image display unit 1305, an observation image of the fundus surface is shown, but the horizontal direction is the x-axis and the vertical direction is the y-axis. Then, a tomographic image in the xy cross section of the fundus is displayed on the cross section image display unit 1303.
Then, the first vertical section image display unit 1302 and the second vertical section image display unit 1306 display tomographic images of the fundus along the two cross sections in the z direction indicated by the dotted lines in the front image display unit 1305. To. The tomographic image of the yz cross section is displayed on the first vertical cross section image display unit 1302, and the tomographic image of the xz cross section is displayed on the second vertical cross section image display unit 1306.
On the operation guide image display unit 1307, for example, an image obtained by superimposing a site to be operated on on an image obtained before the operation can be displayed.

Here, in the ophthalmic microscope of the first embodiment, since the optical axis of the OCT optical system and the optical axis of the SLO optical system are coaxial, the observation image of the fundus surface acquired by the SLO optical system is used. , There is no positional deviation from the tomographic image of the fundus acquired by the OCT optical system. Therefore, there is no positional deviation between the observation image of the fundus surface displayed on the front image display unit 1305 and the tomographic image on the xy cross section displayed on the cross-sectional image display unit 1303, and accurate alignment is possible. Further, the two cross sections shown by the dotted lines on the front image display unit 1305, the tomographic image of the yz cross section displayed on the first vertical cross section image display unit 1302, and the xz cross section displayed on the second vertical cross section image display unit 1306. There is no misalignment with the tomographic image of, and accurate alignment is possible.

FIG. 5 is a schematic view showing the shape of an objective lens used in the ophthalmic microscope of the first embodiment. 5 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 5 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 5 (A).
As shown in FIG. 5A, the objective lens 2 used in the first embodiment has a shape in which a hole 201 is provided in the center of the circular lens. Then, the optical path P-500 of the OCT optical system passes through the hole. In the ophthalmic microscope of the first embodiment, the optical path P-400L of the observation optical system for the left eye, the optical path P-400R of the observation optical system for the right eye, and the optical path P-300 of the illumination optical system are respectively. It is transmitted through different parts of the objective lens 2. Although not shown, the optical path of the sub-observation optical system passes through the vicinity of the optical path P-400L of the observation optical system for the left eye.
Next, as shown in FIG. 5B, the cross-sectional shape of the objective lens 2 is a shape in which a hole is formed in the center of the convex lens.

1-3. Shape of objective lens A circular lens can be used as the objective lens used in the ophthalmic microscope of the present invention, but the angle formed by the optical axis of the OCT optical system and the optical axis of the observation optical system can be reduced. Preferably, for that purpose, it is preferable to use an objective lens having a partial shape of a circular lens or an objective lens having a shape in which a notch or a hole is provided in the circular lens.

In the present invention, the "partial shape of a circular lens" refers to a shape obtained by cutting out a part of a circular lens when viewed in a plan view from the optical axis direction of the lens, and is not limited to these, but for example, the left. A lens having a semicircular shape, a fan shape, a rectangular shape, or the like can be used so that the optical path of the observation optical system for the eye and the optical path of the observation optical system for the right eye pass through.
Further, in the present invention, the "shape in which a notch or a hole is provided in a circular lens" means a shape in which a notch or a hole is provided when viewed in a plan view from the optical axis direction of the lens, and is limited to these. However, for example, a lens having a notch or a hole in a portion through which the optical path of the OCT optical system passes can be used.
In order to secure a sufficient space for arranging the optical elements of the OCT optical system, it is preferable to use an objective lens having a partial shape of the circular lens rather than providing a notch or a hole in the circular lens.

Using a lens having such a shape, the optical path of the OCT optical system can pass through a portion of the circular lens in which the cut lens does not exist, or a notch or a hole provided in the lens. As a result, the angle formed by the optical axis of the OCT optical system and the optical axis of the observation optical system can be reduced without the optical axis of the OCT optical system passing through the objective lens.
In the present invention, the angle formed by the optical axis of the OCT optical system and the optical axis of the observation optical system (either the optical axis of the left or right observation optical path) is preferably 1 to 15 °, and more preferably. It is preferably 4 to 10 °, more preferably 6 to 8 °.

In the ophthalmic microscope of the present invention, a circular lens or a lens composed of a circular lens portion is divided into two, and one of the divided lenses is used as an objective lens through which the optical axis of the observation optical system is transmitted, and the other is divided. The lens can be an objective lens through which the optical axis of the OCT optical system is transmitted.
Here, as the "lens composed of a portion of a circular lens", a lens having the above-mentioned "partial shape of a circular lens" can be used.
If the positions of the divided lenses can be controlled independently, the observation optical system and the OCT optical system can be controlled independently.

1-4. It is preferable that the OCT optical system of the second embodiment can be additionally incorporated as an extended function into an ophthalmologic microscope having an observation optical system and an illumination optical system. The present inventors have found that in order to additionally incorporate the OCT optical system in this way, the optical path of the OCT optical system can be bent twice to be adapted to the original function of the microscope and incorporated compactly.

That is, in the ophthalmic microscope of the present invention, the OCT optical system is
A first optical member that guides the light from the OCT light source in the direction of the first optical axis, and
A first reflective member that guides the light guided in the first optical axis direction in the second optical axis direction substantially orthogonal to the first optical axis direction, and
A second optical member that relays the light guided in the second optical axis direction, and
A second reflecting member that guides the light relayed by the second optical member in the direction of the third optical axis substantially orthogonal to the direction of the second optical axis.
It is preferable to have an OCT objective lens arranged on the third optical axis direction and irradiating a predetermined portion of the eye to be inspected with light guided in the third optical axis direction.
With such an optical configuration, the OCT optical system can be compactly incorporated in accordance with the original function of the ophthalmologic microscope.

Hereinafter, an example of an embodiment of the ophthalmologic microscope of the present invention having an OCT optical system in which the optical path is bent twice will be described in detail with reference to the drawings.
6 and 7 are drawings schematically showing a second embodiment, which is another example of the ophthalmic microscope of the present invention.

FIG. 6 is a schematic side view of the ophthalmic microscope 1, and FIG. 7 is a schematic front view.
As shown in FIGS. 6 and 7, the ophthalmic microscope 1 is provided with an OCT device 5.
The ophthalmic microscope 1 includes an illumination optical system 300 (not shown in FIG. 7), an observation optical system 400, and an OCT optical system 500.
The observation optical system 400 can observe a predetermined portion of the eye 8 to be inspected. As referred to in FIG. 6, the illumination optical system 300 can illuminate the portion to be observed of the eye 8 to be inspected.

The OCT device 5 attached to the ophthalmic microscope 1 can acquire a tomographic image of the eye 8 to be inspected. The OCT optical system 500 is incorporated in the ophthalmologic microscope 1 as a part of the OCT device 5. The OCT optical system 500, the front lens 14, and the reflective surface (cornea, retina, etc.) of the eye 8 to be inspected constitute a reciprocating light guide path for the measurement light.
As is shown in FIG. 7, the observation optical system 400 includes an observation optical system 400R for the right eye and an observation optical system 400L for the left eye. Note that FIG. 6 shows the entire configuration of the observation optical system 400R for the right eye, and only the objective lens 2 shared with the observation optical system 400R for the right eye is shown for the observation optical system 400L for the left eye. ..
Further, as is clearly shown in FIG. 7, the optical axis O-400R of the observation optical system for the right eye and the optical axis O-400L of the observation optical system for the left eye 400L pass through the objective lens 2, respectively.
In the present embodiment, as shown in FIG. 6, the illumination optical system 300 and the observation optical system 400 are housed in the ophthalmic microscope main body 6. Further, the OCT optical system 500 and the SLO optical system 1500 are housed in the function expansion unit 7. In FIGS. 6 and 7, the main body 6 of the ophthalmic microscope is shown by a long-dashed line, and the function expansion unit 7 is shown by a broken line.
The function expansion unit 7 is detachably / attached to the ophthalmic microscope main body 6 by a joint portion (not shown).

As shown in FIGS. 6 and 7, the OCT device 5 includes an OCT unit 10 and a function expansion unit 7.
The function expansion unit 7 includes an OCT optical system 500 and an SLO optical system 1500 (not shown in FIG. 7).
8 is a perspective view of the OCT optical system 500, FIG. 9 is a plan view, FIG. 10 is a side view, and FIG. 11 is a front view. In FIGS. 9 and 11, the collimating lens 502, the scanning function unit 503, and the first optical member 510 (described later) are not shown.
In FIGS. 8 and 10, the OCT optical system 500 includes a collimating lens 502, a scanning function unit 503, a first optical member 510, a first reflection member 511, a second optical member 512, a second reflection member 513, and an OCT objective. It is configured to include a lens 507.

The scanning function unit 503 is a two-dimensional scanning mechanism having optical scanners 503a and 503b. The scanning function unit 503 is provided on the back surface side (far side from the observer) of the ophthalmologic microscope main body 6.
The first optical member 510 is an OCT imaging lens, and guides the light scanned by the scanning function unit 503 in the direction of the first optical axis O-501. The first optical axis O-501 is formed from the back to the front at the right outer position of the ophthalmic microscope main body 6 when the ophthalmic microscope main body 6 is viewed from the front, and is formed by the scanning function unit 503. The scanned light guides the first optical axis O-501 from the back toward the front side.

As shown in FIGS. 8, 9, 10 and 11, the light guiding the first optical axis O-501 is orthogonal to the direction of the first optical axis O-501 by the first reflecting member 511. The light is guided in the direction of the second optical axis O-502.
In this embodiment, as referred to in FIG. 7, the second optical axis O-502 is formed so as to face from the right outside to the inside of the ophthalmologic microscope main body 6.
A second optical member 512 is arranged on the second optical axis O-502, and the light passing through the second optical member 512 is directed downward by the second reflection member 513 (abbreviated to the second optical axis O-502). It is reflected (in the direction orthogonal to it). This reflected optical path is shown in the third optical axis direction O-503.

In the present embodiment, as shown in FIG. 6, the objective lens 2 has a partial shape of a circular lens in which the lens is cut so as to have a cut surface substantially parallel to the optical axis O-400.
In the present embodiment, the OCT objective lens 507 is housed in the portion where the lens of the circular lens is cut off.
The light guided in the third optical axis direction O-503 is focused by the OCT objective lens 507 at a predetermined position on the 8 side of the eye to be inspected.
In FIGS. 6 and 7, the front focal position U0 of the objective lens 2 is in front of the eye 8 to be inspected, and the front lens 14 is arranged between the eye 8 to be inspected and the front focal position U0.

The front lens 14 is a lens used when observing the retina of the fundus, and the front lens 14 has an optical axis O-300, O-400L, O-400R in front of the eye to be inspected by means of movement (not shown). It is inserted on O-503. In this case, the anterior focal position U0 of the objective lens 2 is conjugate with the retina of the fundus. When observing the anterior segment of the cornea, iris, etc., the anterior lens 14 is detached from the front of the eye 8 to be inspected for observation.

As described above, the optical axis O-503 of the OCT optical system 500 passes through the objective lens 507 for OCT, and the optical axis O-503 of the OCT optical system 500 is separated from the optical axis O-400 of the observation optical system 400. ing.
Therefore, the OCT optical system 500 and the observation optical system 400 are independent of each other.

As shown in FIG. 6, the SLO optical system 1500 includes an SLO light source 16, an optical fiber 1502, a collimating lens 1503, an illumination field aperture 1504, a dichroic mirror 1501, a half mirror 1505, an optical aperture 1506, a condenser lens 1507, and reflected light. It includes a detector 1508 and an image creating unit 1509.
Although the SLO light source 16 is provided outside the function expansion unit 7, one end of the optical fiber 1502 is connected to the SLO light source 16 so as to be connected to the function expansion unit 7. The light rays generated by the SLO light source 16 are emitted from the other end of the optical fiber 1502. The emitted light beam passes through the collimating lens 1503 and the illumination field aperture 1504, is reflected by the half mirror 1505, is further reflected by the dichroic mirror 1501, and merges coaxially with the measurement light of the OCT optical system 500.

As shown in FIG. 1, the combined light rays of the SLO optical system 1500 are two-dimensionally scanned by the optical scanners 503a and 503b in the same manner as the measurement light of the OCT optical system 500. By using the optical scanners 503a and 503b, which require a complicated mechanism, in common for the OCT optical system 500 and the SLO optical system 1500, the function expansion unit 7 can be miniaturized and reduced in cost.

Also in the ophthalmic microscope of the second embodiment, since the optical axis of the OCT optical system and the optical axis of the SLO optical system are coaxial, the observation image of the fundus surface acquired by the SLO optical system and the OCT optical system are used. There is no positional deviation from the tomographic image of the fundus acquired by the system. Therefore, as shown in FIG. 4, there is no positional deviation between the observation image of the fundus surface displayed on the front image display unit 1305 and the tomographic image on the xy section displayed on the cross-sectional image display unit 1303, and the image is accurate. Alignment is possible. Further, the two cross sections shown by the dotted lines on the front image display unit 1305, the tomographic image of the yz cross section displayed on the first vertical cross section image display unit 1302, and the xz cross section displayed on the second vertical cross section image display unit 1306. There is no misalignment with the tomographic image of, and accurate alignment is possible.

1-5. Third Embodiment The shape of the objective lens used in the third embodiment, which is another example of the ophthalmic microscope of the present invention, is shown in FIG. 12 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 12 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 12 (A).
As shown in FIG. 12A, the objective lens 2 used in the third embodiment has a shape in which a notch is provided in a part of the circular lens. Then, the optical path P-500 of the OCT optical system passes through the notched portion.
Further, as shown in FIG. 12B, the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting out a part of the convex lens.

1-6. Fourth Embodiment The shape of the objective lens used in the fourth embodiment which is another example of the ophthalmic microscope of the present invention is shown in FIG. 13 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 13 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 13 (A).
As shown in FIG. 13A, the objective lens 2 used in the fourth embodiment has a shape in which a part of a circular lens is cut out in a rectangular shape, and the optical path P of the observation optical system for the left eye. -400L and the optical path P-400R of the observation optical system for the right eye pass through different parts of the objective lens 2. Then, the optical path P-500 of the OCT optical system and the optical path P-300 of the illumination optical system pass in the vicinity of the objective lens 2.
Further, as shown in FIG. 13B, the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting out a part of the convex lens.

1-7. Fifth Embodiment The shape of the objective lens used in the fifth embodiment, which is another example of the ophthalmic microscope of the present invention, is shown in FIG. 14 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 14 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 14 (A).
As shown in FIG. 14A, the objective lens 2 used in the fifth embodiment has a shape in which a part of a circular lens is cut out in a semicircular shape, and the optical path of the observation optical system for the left eye. The P-400L, the optical path P-400R of the observation optical system for the right eye, and the optical path P-300 of the illumination optical system each pass through different parts of the objective lens 2. Then, the optical path P-500 of the OCT optical system passes in the vicinity of the objective lens 2.
Further, as shown in FIG. 14B, the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting out a part of the convex lens.

1-8. Sixth Embodiment The shape of the objective lens used in the sixth embodiment, which is another example of the ophthalmic microscope of the present invention, is shown in FIG. 15 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 15 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 15 (A).
As shown in FIG. 15A, the objective lens 2 used in the sixth embodiment has a shape in which a part of a circular lens is cut out in a crescent shape, and the optical path P of the observation optical system for the left eye. -400L, the optical path P-400R of the observation optical system for the right eye, and the optical path P-300 of the illumination optical system each pass through different parts of the objective lens 2. Then, the optical path P-500 of the OCT optical system passes in the vicinity of the objective lens 2.
Further, as shown in FIG. 15B, the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting out a part of the convex lens.

1-9. Seventh Embodiment The shapes of the objective lens and the objective lens for OCT used in the seventh embodiment, which is another example of the ophthalmic microscope of the present invention, are shown in FIG. 16 (A) is a view seen from the direction of the optical axis of the objective lens, and FIG. 16 (B) is a cross-sectional view of the plane including the line segment AA'of FIG. 16 (A).
As shown in FIG. 16A, the objective lens and the objective lens for OCT used in the seventh embodiment are obtained by dividing a circular lens into two. The divided lens 2 is used as an objective lens, and the optical path P-400L of the observation optical system for the left eye, the optical path P-400R of the observation optical system for the right eye, and the optical path P-300 of the illumination optical system are used. It is transparent. Then, the other divided lens 507 is used as an objective lens for OCT, and the optical path P-500 of the OCT optical system passes through it.
Further, as shown in FIG. 16B, the cross-sectional shape of the objective lens 2 and the OCT objective lens 507 is a shape obtained by dividing the convex lens into two.

2. 2. Function expansion unit The function expansion unit of the present invention can be attached to and detached from an ophthalmic microscope, and the function of OCT can be added to the ophthalmic microscope.
The function expansion unit of the present invention includes an illumination optical system that illuminates the eye to be inspected, an optical path of the observation optical system for the left eye and an optical path of the observation optical system for the right eye for observing the eye to be inspected illuminated by the illumination optical system. Used for an ophthalmic microscope having an observation optical system having an observation optical system and an objective lens in which the optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye of the observation optical system are commonly transmitted. It is a thing.
The function expansion unit of the present invention has a joint portion that can be attached to and detached from the ophthalmic microscope and a joint portion.
An OCT optical system that scans the measurement light for inspecting the eye to be inspected by optical coherence tomography, and
It has an SLO optical system that scans visible light, near-infrared, or infrared light to guide the subject to the eye.
When the function expansion unit is attached to the ophthalmic microscope via the joint portion, the optical axis of the OCT optical system does not transmit through the objective lens through which the optical axis of the observation optical system is transmitted, and the observation optical is transmitted. The optical axis of the system and the optical axis of the OCT optical system are non-coaxial, and
The optical axis of the OCT optical system and the optical axis of the SLO optical system are substantially coaxial with each other, and the SLO optical system is characterized in that the portion of the eye to be inspected scanned by the OCT optical system can be observed.

The OCT optical system of the function expansion unit of the present invention is independent of the observation optical system of the ophthalmologic microscope, and has the effect of enabling unitization and increasing the degree of freedom in optical design. Further, since the function expansion unit of the present invention can be attached to and detached from the ophthalmic microscope via the joint portion, there is an effect that the function of OCT can be easily added to the ophthalmic microscope. Further, the function expansion unit of the present invention has an SLO optical system that guides a light ray substantially coaxial with the optical axis of the OCT optical system to the eye to be inspected, whereby the image to be inspected is not deviated from the image obtained by the OCT optical system. It has the effect of being able to observe.

The "joint portion" of the function expansion unit of the present invention is not particularly limited as long as the function expansion unit and the ophthalmologic microscope can be attached and detached, and the present invention is not limited to these, but for example, fitting. It can be a joint part that is connected by alignment or a joint part that is connected by using screws.

Specific examples of the function expansion unit of the present invention include the function expansion unit (dotted line indicated by reference numeral 7 in FIGS. 1, 6 and 7) in the ophthalmic microscope of the first embodiment and the ophthalmic microscope of the second embodiment. It is as described as (the part surrounded by).

3. 3. Function expansion set The function expansion set of the present invention is described in 2. above. The function expansion unit described in the above and an interchangeable objective lens for exchanging the objective lens of the ophthalmologic microscope are included, and these are a set.
Here, as the replacement objective lens, the above 1-3. An objective lens having the shape described in 1 can be used.
As a specific example of the interchangeable objective lens, the objective lenses (FIGS. 5 and 12 to 16) used in the first embodiment and the third to seventh embodiments can be used.

Since the function expansion unit of the present invention can be attached to and detached from the ophthalmic microscope via the joint portion, the function of OCT can be easily added to the ophthalmic microscope. Further, the function expansion set of the present invention has an SLO optical system that guides a light ray substantially coaxial with the optical axis of the OCT optical system to the eye to be inspected, whereby the image to be inspected is not deviated from the image obtained by the OCT optical system. It has the effect of being able to observe.

The ophthalmic microscopes, function expansion units, and function expansion sets of the present invention are useful in the industry for manufacturing ophthalmic medical devices.

The reference numerals used in FIGS. 1 to 16 indicate the following.
1 Ophthalmic microscope 2 Objective lens 300 Illumination optics 301 Optical fiber 302 Emission light aperture 303 Condenser lens 304 Illumination field aperture 305 Collimated lens 306 Reflection mirror 400 Observation optics 400L Observation optics for the left eye 400R Observation optics for the right eye System 400S Secondary observation optical system 401 Variable magnification lens system 401a, 401b, 401c Zoom lens 402 Beam splitter 403 Imaging lens 404 Image erecting prism 405 Eye width adjustment prism 406 Field aperture 407 Eyepiece lens 408 Prism 408a Prism reflection surface 409 connection Image lens 410 Reflective mirror 411 Assistant eyepiece 5 OCT device 500 OCT optical system 501 Optical fiber 502 Collimated lens 503 Scanning function unit 503a, 503b Optical scanner 504 Relay optical system 505 First lens group 506 Second lens group 507 Objective for OCT Lens 508 Reflection mirror 509 Illumination field aperture 510 1st optical member 511 1st optical member 512 2nd optical member 513 2nd reflective member 6 Ophthalmic microscope body 7 Function expansion unit 8 Subject 8a Retina 9 Illumination light source 10 OCT unit 1001 OCT Light source unit 1002 Optical fiber 1003 Polarization controller 1004 Optical fiber 1005 Fiber coupler 1006 Optical fiber 1007 Collimeter 1008 Optical path length correction member 1009 Dispersion compensation member 1010 Corner cube 1011 Corimeter 1012 Optical fiber 1013 Polarization controller 1014 Optical fiber 1015 Attenuator 1016 Optical fiber 1017 Fiber coupler 1018 Optical fiber 1019 Optical fiber 1020 Optical fiber 1021 Detector 1101 Imaging lens 1102 Reflection mirror 1103 TV camera 1103a Image pickup element 12 Calculation control unit 13 Display unit 1301 Display screen 1302 First vertical section image display unit 1303 Cross section image Display 1304 Processed image display 1305 Front image display 1306 Second vertical section image display 1307 Surgical guide image display 14 Front lens 1500 SLO Optical system 1501 Dycroic mirror 1502 Optical fiber 1503 Collimated lens 1504 Illumination field aperture 1505 Half Mirror 1506 Optical aperture 1507 Condensing lens 1508 Reflected light detector 1509 Image creation unit 16 SLO light source O-300 Illumination optics Optical axis of the system O-400 Optical axis of the observation optical system O-400L Optical axis of the observation optical system for the left eye O-400R Optical axis of the observation optical system for the right eye O-400S Optical axis of the auxiliary observation optical system O-500 Optical axis of OCT optical system, Optical axis of SLO optical system O-501 First optical axis O-502 Second optical axis O-503 Third optical axis P-300 Optical path of illumination optical system P-400L Left eye Optical path of observation optical system P-400R Optical path of observation optical system for right eye P-500 Optical path of OCT optical system Optical path of SLO optical system L0 Optical interference output from OCT light source unit LC Interference light LS Measurement light LR Reference light U0 Front focal position

Claims (13)

An illumination optical system that illuminates the eye to be inspected, an observation optical system having an observation optical system for the left eye and an observation optical system for the right eye for observing the eye to be inspected illuminated by the illumination optical system, and the observation optical system. The optical axis of the observation optical system for the left eye and the optical axis of the observation optical system for the right eye are transmitted in common, and the measurement light for inspecting the eye to be inspected is scanned by optical coherence stromography. In an ophthalmic microscope with an OCT optical system,
The optical axis of the OCT optical system does not pass through the objective lens through which the optical axis of the observation optical system is transmitted, and the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial. The observation optical system, the objective lens, and the OCT optical system are arranged.
It further has an SLO optical system that scans visible light, near-infrared rays, or light rays that are infrared rays and guides the eye to be inspected so as to be substantially coaxial with the optical axis of the OCT optical system. An ophthalmic microscope characterized in that a region including a portion of the eye to be inspected scanned by an OCT optical system can be observed. The OCT optical system is
A first optical member that guides the light from the OCT light source in the direction of the first optical axis,
A first reflecting member that guides the light guided in the first optical axis direction in the second optical axis direction substantially orthogonal to the first optical axis direction.
A second optical member that relays the light guided in the second optical axis direction, and the second optical member.
A second reflective member that guides the light relayed by the second optical member in the direction of the third optical axis substantially orthogonal to the second optical axis direction.
The present invention is characterized by having an OCT objective lens arranged on the third optical axis direction and irradiating a predetermined portion of the eye to be inspected with light guided in the third optical axis direction. The ophthalmic microscope according to 1. The ophthalmologic microscope according to claim 1 or 2, further comprising a deflecting optical element that commonly scans the measurement light of the OCT optical system and the light beam of the SLO optical system. The objective lens has a partial shape of a circular lens or a shape in which a notch or a hole is provided in the circular lens.
The invention according to any one of claims 1 to 3, wherein the optical axis of the OCT optical system passes through a portion where the objective lens does not exist, or a notch or a hole provided in the objective lens. Ophthalmic microscope. Divide the lens consisting of a circular lens or a part of a circular lens into two parts.
One divided lens is used as the objective lens.
The ophthalmologic microscope according to any one of claims 1 to 4, wherein the other divided lens is an OCT objective lens through which the optical axis of the OCT optical system is transmitted. The ophthalmologic microscope according to any one of claims 1 to 5, further comprising an objective lens position control mechanism for adjusting the position of the objective lens or the OCT objective lens of the OCT optical system . The ophthalmologic microscope according to any one of claims 1 to 6, wherein the OCT optical system and the SLO optical system are detachably united. 13. The described ophthalmic microscope. An illumination optical system that illuminates the eye to be inspected, an observation optical system having an observation optical system for the left eye and an observation optical system for the right eye for observing the eye to be inspected illuminated by the illumination optical system, and the observation optical system. In the function expansion unit used for an ophthalmologic microscope having an optical axis of the observation optical system for the left eye and an objective lens that transmits the optical axis of the observation optical system for the right eye in common.
A joint part that can be attached to and detached from the ophthalmic microscope,
An OCT optical system that scans the measurement light for inspecting the eye to be inspected by optical coherence tomography, and
It has an SLO optical system that scans visible light, near-infrared, or infrared light to guide the subject to the eye.
When the function expansion unit is attached to the ophthalmic microscope via the joint portion, the optical axis of the OCT optical system does not transmit through the objective lens through which the optical axis of the observation optical system is transmitted, and the observation optical is transmitted. The optical axis of the system and the optical axis of the OCT optical system are non-coaxial, and
A function expansion unit characterized in that the optical axis of the OCT optical system and the optical axis of the SLO optical system are substantially coaxial with each other, and the portion of the eye to be inspected scanned by the OCT optical system can be observed by the SLO optical system. .. The OCT optical system is
A first optical member that guides the light from the OCT light source in the direction of the first optical axis,
A first reflecting member that guides the light guided in the first optical axis direction in the second optical axis direction substantially orthogonal to the first optical axis direction.
A second optical member that relays the light guided in the second optical axis direction, and the second optical member.
A second reflecting member that guides the light relayed by the second optical member in the direction of the third optical axis substantially orthogonal to the second optical axis direction.
The present invention is characterized by having an OCT objective lens arranged on the third optical axis direction and irradiating a predetermined portion of the eye to be inspected with light guided in the third optical axis direction. The function expansion unit according to 9. The function expansion unit according to claim 9 or 10, further comprising a deflecting optical element that commonly scans the measurement light of the OCT optical system and the light beam of the SLO optical system. A function expansion set comprising the function expansion unit according to any one of claims 9 to 11 and an interchangeable objective lens for exchanging the objective lens. The replacement objective lens has a partial shape of a circular lens or a shape in which a notch or a hole is provided in the circular lens.
When the objective lens is replaced with the replacement objective lens and the function expansion unit is attached to the ophthalmologic microscope via the joint portion,
The functional expansion set according to claim 12, wherein the optical axis of the OCT optical system passes through a portion where the replacement objective lens does not exist, or a notch or a hole provided in the replacement objective lens. ..

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