JP6969764B1 - System including weighing mixer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To measure the length of separating a final mixture of an intended formulation by using a plurality of stick intermediates in which the active ingredient per length is uniformly produced in advance, and to measure the length thereof. It is to provide a metered mixing system that can be produced by obtaining and mixing the required amount of active ingredient with the simple operation of separating the minute stick intermediates. SOLUTION: The length of each stick intermediate is measured by using a plurality of kinds of stick intermediates having a uniform active ingredient per length, which are produced by mixing the necessary additives with the active ingredient. A system comprising a metering mixer that produces the final mixture of the intended formulation by cutting and separating. [Selection diagram] Fig. 1

Description

The present invention relates to a system comprising a metering mixer to produce a final mixture of the intended formulation, in particular a system comprising a metering mixer using a stick intermediate.

Conventionally, when a mixture is produced from a plurality of types of materials, it has been usual to measure the amount of each material by measuring the weight of each material. Weighing the amount by weight measurement requires skillful skill to operate the weight measuring device, and is a complicated work.
In conventional dispensing or self-adjustment, there has been scoring that divides tablets at the lengths or positions provided at the time of manufacture, such as 1/2, 1/4, according to the dividing line provided in advance, but it is optional. It was a method that could not be divided according to the length or position of. If it is divided by a length or position other than the predetermined dividing line, it requires a very sophisticated and complicated work to accurately measure the quantity.

Patent Document 1 describes a technique for measuring a quantity by using a large amount of small granular material and changing the volume to be administered.
It has an adjuster that sets the volume of the dosing chamber, the adjuster being movably attached to at least one that can be moved back and forth parallel to the axis of rotation by a drive device to change the volume of the dosing chamber. It is a technique related to a dosing device, which is characterized by a dosing unit having a regulatory element.

As a result of the placement between the transfer openings and the substantially horizontal alignment of the axis of rotation, the regulator that changes the volume within the administration chamber can be guided in a simple manner, regardless of the chamber position. It is stated that the dosing device can be kept compact because it can be.

However, focusing on the metering and mixing function, the use of an amorphous small granular preparation requires an administration chamber for accommodating it, and an adjusting device for changing the volume in the administration chamber is required for weighing. It was something to do.

Special Table 2006-526629

The subject of the present invention is to measure the length corresponding to the required amount of the final mixture of the intended formulation by using a plurality of stick intermediates in which the active ingredient per length is uniformly produced in advance, and the length thereof. It is to provide a system including a metering mixer that can be produced by weighing and mixing the required amount of active ingredient with the simple operation of cutting and separating the stick intermediate of.
Here, the stick intermediate is a final mixture produced by mixing a predetermined active ingredient with a necessary additive and formed into a rod shape having a uniform active ingredient per length, which is a raw material. It is a term that refers to the material used in the intermediate process until it is produced.

From the first aspect of the present invention, a plurality of active ingredients having a uniform length, which are produced in a rod shape having a predetermined diameter or cross-sectional area by mixing the additives required for the active ingredient in advance by a stick intermediate manufacturer. A system for dispensing or self-adjusting drugs required for drug treatment using different types of stick intermediates, intended by measuring, cutting and separating the length of each of the stick intermediates. A system is provided that includes a metered mixer that produces the final mixture of formulations.
Here, the plurality of types of stick intermediates may include stick intermediates having the same type of active ingredient but different cross-sectional areas or uniform concentrations.
Further, the stick intermediate may have a shape of an end portion (hereinafter referred to as a rear end portion) that is not used, depending on the type or size of the active ingredient. By making changes to the shapes that characterize the rear end of the stick intermediate, such as the length of the rear end, the shape of the cross section, and the area of the cross section, the distinctiveness of the stick intermediate is enhanced and the stick intermediate is removed. You can prevent mistakes.

Here, the additive may be at least one selected from a base solvent, a binder, a lubricant, and a pH adjuster.

The stick intermediate may be coated.

The system may further include a magazine that can accommodate a plurality of the stick intermediates used for the supply and distribution of the stick intermediates.
Including the magazine in the system facilitates handling in the supply and distribution of stick intermediates and also facilitates quality maintenance.

In the above system, a) a locking means for producing the final mixture and then mixing and locking the necessary additives, and b) after producing the final mixture, the necessary additives are mixed and liquid. Liquid producing means to be produced, c) After producing the final mixture, it may further contain at least one selected from the packaging means to be packaged.

The metering mixer may be capable of using a stick intermediate in which the cross-sectional area is increased or decreased by changing the diameter of the cross section thereof or the like according to the required amount of the raw material as the active ingredient.

The system may be a system including an automatic dispensing machine adapted for individual drug treatment, and the measuring and mixing machine may be incorporated in the automatic dispensing machine.

The above system may be a system for blending cooking spices.

The above system may be a system used for measuring and mixing raw materials in a factory production process.

The system may be a system used for metering and mixing raw materials in at least one selected from personalized cosmetics, quasi-drugs or perfume purification, and color production.

FIG. 1 is a schematic diagram showing a hardware configuration of the system of this embodiment. FIG. 2 is a schematic view of a stick intermediate and a magazine used in the metering mixer of this embodiment. FIG. 3 is a flowchart showing the production process of the stick intermediate of this embodiment. FIG. 4 is a schematic view showing the main configuration of the metering mixer of this embodiment. FIG. 5 is a schematic view showing the main configuration of the locker of this embodiment. FIG. 6 is a schematic view showing the main configuration of the liquid generator of this embodiment. FIG. 7 is a schematic view showing the main configuration of the packaging machine of this embodiment. FIG. 8 is a schematic side perspective view showing the main configuration of the dosing machine of this embodiment. FIG. 9 is an image diagram showing a state in which the final mixture cylinder produced by the metering mixer of this embodiment is discharged. FIG. 10 is an image diagram showing how the final mixture in the cylinder is dosed by pushing out the plunger rod.

For the purpose of providing a system that can accurately generate the final mixture of the intended formulation with a simple operation, a plurality of stick intermediates in which the active ingredient per length is uniformly produced in advance are used, and the stick intermediates thereof are used. It was realized by a system including a metering mixer equipped with a function to measure the length to separate the body and separate the stick intermediate for that length.

(system configuration diagram)
FIG. 1 is a schematic diagram showing a hardware configuration included in the system of this embodiment. In this embodiment, the system of the present invention is applied to a dispensing business or self-adjustment, but the scope of application of the present invention is not limited to this. For example, it can be applied to a system used for measuring and mixing raw materials in the purification of cosmetics, quasi-drugs or perfumes or the production of paint colors. It can also be applied to cooking spice blending systems. Furthermore, the scale of the system can be applied from a compact system applied for personal use to a factory production process.

The description of the configuration included in this embodiment will be continued. It is composed of magazines 1001a, 1001b, 1001c for accommodating different types of stick intermediates, a metering / mixing machine 1003, a tableting machine 1010, a liquid generator 1011 and a packaging machine 1012.

Here, three types of stick intermediates, stick intermediates 1002a, 1002b and 1002c, are used by the metering mixer 1003. A linear actuator linked to the rotation operation of the dials 1004a, 1004b, and 1004c by the user linearly moves the stick intermediate whose tip is aligned with the cutting position.

The length of each stick intermediate to be cut and separated is measured from the initial position of the stick intermediate and the amount of linear movement, and is displayed on the display units 1005a, 1005b, 1005c corresponding to the stick intermediates 1002a, 1002b, 1002c. NS.

When the linear movement to the position to be cut to the desired length is completed, the user presses the cut button 1006. An intermediate stick of a desired length is cut and separated by a cutter in the cutting separation section that operates in conjunction with pressing down on the cutting button. The cut-separated portion will be described later with reference to FIG.

The cut and separated intermediate sticks are collected and mixed by the collecting / mixing unit 1007. Then, it is homogenized in the homogenization section 1008 to produce the final mixture 1009.

The resulting final mixture 1009 is supplied to the tableting machine 1010 for tableting, supplied to the liquid generator 1011 for liquefaction, and supplied to the packaging machine 1012 for packaging. Has been built.

Here, three types of stick intermediates are used, but the types of stick intermediates that can be adopted in the present invention are not limited to these, and may be appropriately changed according to the composition of the desired final mixture. Can be done.
Further, it is configured as an automatic dispensing machine incorporating at least one selected from the above-mentioned weighing mixer, a tableting machine, a liquid generator, and a packaging machine, and a control for controlling the incorporated equipment by inputting a dispensing recipe in advance. The device may operate the linear actuator, the chuck, and the cutting / separating portion.

FIG. 2 is a schematic view of a stick intermediate and a magazine used in the metering mixer of this embodiment.
Here, the stick intermediate is formed into a rod shape having a circular cross section. Here, the diameters 2001a, 2001b, and 2001c of the cross sections of the stick intermediates 1002a, 1002b, and 1002c are Ra, Rb, and Rc, respectively. Stick intermediates having different diameters and different cross-sectional areas are adopted depending on the amount of active ingredient required for the final mixture.
Here, a rod-shaped stick intermediate having a circular cross section was adopted, and a stick intermediate having a different cross-sectional area depending on the size of the active ingredient was adopted. However, the valuation of the stick intermediate that can be adopted in the present invention is , Not limited to this. Not only the size of the required active ingredient but also the length of the stick intermediate, the shape of the cross section or the cross-sectional area may be different depending on the type of the active ingredient.

The rear ends 2002a, 2002b, 2002c of each stick intermediate have been modified in shape to identify the type of stick intermediate.
The rear end portion 2002a is changed by forming a characteristic notch by partially reducing the size of the rear end portion 2002a after making the cross section square.
The rear end portion 2002b is modified by forming two flange-shaped protrusions larger than the diameter of the main body.
The rear end portion 2002c is modified by forming one flange-shaped protrusion after making the diameter smaller than that of the main body.
In this way, by changing the shape of the rear end of the stick intermediate that is not used for weighing and mixing according to the type and size of the active ingredient, the distinctiveness of which type of stick intermediate is enhanced, and for weighing and mixing work. It has the effect of preventing the person concerned from making a mistake in the intermediate.

The surface of the stick intermediate is coated and protected. Further, for protection from damage in supply or distribution and convenience in handling in transportation, each stick intermediate is stored in magazines 1001a, 1001b, 1001c.
When used in a weighing mixer, it is taken out from the magazine outlets 2002a, 2002b, 2002c.
Here, the micro RFID may be attached or embedded in each magazine or individual intermediate stick for management in transportation and storage of the magazine, and the management in transportation and storage may be streamlined by reading the RFID.

FIG. 3 is a flowchart showing the production process of the stick intermediate of this embodiment.
In the active ingredient charging step S3001, the stick intermediate manufacturer charges the stick intermediate producing kettle with the amount of active ingredient required for the stick intermediate to be produced.
Here, with respect to the stick intermediates having the same active ingredient, the amount of the stick intermediates added per stick intermediate is changed, and the stick intermediates having different concentrations are added.

In the additive mixing step S3002, the additive required for the charged active ingredient is mixed by the stick intermediate manufacturer.
Here, as the additive, a base solvent, a binder, a lubricant, a pH adjuster and the like are adopted.

In the homogenization step S3003, the charged active ingredient and the additive are stirred and homogenized by the stick intermediate manufacturer.

In the molding step S3004, the mixture is made uniform by the stick intermediate manufacturer into a mold in which the main body is a rod having a predetermined cross-sectional shape and the shape of the rear end is deformed. The mixture is injected and hardened into a rod shape with a deformed rear end.
Of the above additives, the binder may be mixed in this molding step.

In the coating step S3005, the stick intermediate body is completed by coating the surface of the rod-shaped solidified mixture by the stick intermediate manufacturer.

In the magazine storage step S3006, a predetermined number of stick intermediates coated and completed by the stick intermediate manufacturer are stored in the magazine.

In the supply / distribution step S3007, the magazine containing the stick intermediate is distributed by the stick intermediate manufacturer, the supplier or the distributor, and is supplied to the consumer of the stick intermediate.

The stick intermediate, which is formed into a rod shape having a predetermined diameter or cross-sectional area by uniformly producing the density of the active ingredient in this way, is easier to handle than the small granular active ingredient and has a length that does not require skill. There is an effect that the weighing accuracy can be obtained by the measuring operation.
In addition, by producing stick intermediates having the same type of active ingredient but different concentrations of the active ingredient, a desired dose can be obtained by using stick intermediates having different concentrations in the field of dispensing or self-adjustment. Has the effect of facilitating accurate weighing.
Further, since the coating is applied to the surface and stored in the magazine, there is less risk of damage during transportation and storage, and quality maintenance and handling in supply and distribution become easy. In addition, it will be easier for the supplied consumers to handle it in storage and use.

FIG. 4 is a schematic view showing the functional configuration of the metering mixer of this embodiment.
Here, the same drawing numbers are shown for the parts shown in FIG.
The metering mixer 1003 has a stick intermediate insertion port 4001a, 4001b, 4001c, a linear actuator 4002a, 4002b, 4002c, a chuck 4003a, 4003b, 4003c for fixing the stick intermediate moved by the linear actuator at that position, and a cutting separation. It is composed of parts 4004a, 4004b, 4004c, a collecting / mixing part 1007, and a homogenizing part 1008.

The weighing mixer is used by first selecting the required stick intermediate and inserting it into any or all outlets.

The stick intermediate inserted until the tip is aligned with the cutting position is linearly moved by the linear actuators 4002a, 4002b, 4002c interlocked with the rotation operation of the dials 1004a, 1004b, 1004c shown in FIG.

The length of each stick intermediate to be cut and separated is measured from the initial position and the linear movement amount set by adjusting the tip to the cutting position, and is displayed on the display units 1005a, 1005b, 1005c shown in FIG. NS.

The plurality of stick intermediates whose lengths corresponding to the required capacities were measured were fixed by the chucks 4003a, 4003b, 4003c in a state of protruding from the cutting separation portions 4004a, 4004b, 4004c by the length thereof, and cut. It is cut and separated by the separation portions 4004a to 4004c.
The operation for weighing is to initially set the tip of the stick intermediate in a predetermined initial position and measure the length, which is the linear movement amount, so that the length corresponding to the required capacity protrudes from the cutting separation part. Since it is sufficient, no special operation or proficiency in operation is required, and it is possible to realize the accuracy of weighing the quantity more easily than the measurement of weight or volume.

Here, the number of insertion ports, linear actuators, cutting separation parts and chucks is three, but the number of insertion ports, linear actuators, cutting separation parts and chucks of the weighing mixer of the present invention is limited to three. Instead, it is possible to adopt a configuration that is increased or decreased as needed.

The stick intermediate 4005 that has been cut and separated from the original stick intermediate is collected and mixed by the collecting / mixing unit 1007.
The collected and mixed stick intermediates are chopped into fine pieces by the homogenizer 4006 in the homogenization section 1008 and homogenized to produce the final mixture 1009.
The final mixture produced is discharged from the discharge port 4007.

As described above, the diameter of the cross section is increased or decreased to Ra, Rb or Rc according to the required amount of the raw material as the active ingredient, and stick intermediates having different cross-sectional areas are used.

FIG. 5 is a schematic plan view showing the main configuration of the lock press 1010.
A tableting machine feeder 5001 adapted to the shape of the discharge port 4007, a plurality of recesses 5002 for receiving the final mixture supplied from the tableting machine feeder, and a pressurizing unit 5003 for compressing the final mixture stored in the recesses with a pestle. , And a discharge unit 5004 for discharging the compressed and formed tablets.

FIG. 6 is a schematic side perspective view showing the main configuration of the liquid generator 1011.
It consists of a liquid generator inlet 6001, a solution inlet 6002, a stirrer 6003, and an outlet 6004 for taking out the liquid product, which are adapted to the shape of the discharge port 4007.

FIG. 7 is a schematic side perspective view showing the main configuration of the packaging machine 1012.
A storage unit 7002 having a packing machine input port 7001 adapted to the shape of the discharge port 4007, a distribution unit 7003 for distributing the charged final mixture, a pack unit 7004 for packing the distributed final mixture, and a final mixture are provided. It has a configuration of a discharge unit 7005 for discharging the packed drug pack and a drug pack 7006 for discharging after the packaging is completed.

The above configurations may be combined and applied to a system including an automatic dispensing machine adapted for individual drug treatment. The metering / mixing machine shown here may be incorporated in the automatic dispensing machine. The active ingredients required for dispensing or self-adjusting the drug required for the targeted individual's drug treatment are provided as intermediate sticks housed in a magazine.

(Medication machine and metering mixer incorporated in the dosing machine)
FIG. 8 is a schematic side perspective view showing the main configuration of the dosing machine of this embodiment.
The dosing machine 8001 incorporates the metering / mixing machine 8002 having the configuration shown in the first embodiment inside the dosing machine housing. The mixture produced by the metering mixer 8002 is provided so as to be discharged to the cylinder 8004 from the discharge port 8003 provided with the valve mechanism. It is provided so as to administer from the dosing port 8006 by the operation of the plunger rod 8005.
Here, by keeping the size of the dosing machine housing at least 8 cm or less in the horizontal direction and 15 cm or less in the vertical direction, which is the so-called smartphone size or less, the individual can easily carry it in a pocket or the like. And.

FIG. 9 is an image diagram showing a state in which the final mixture 9001 produced by the metering mixer 8002 of this embodiment is discharged to the cylinder 8004.

FIG. 10 is an image diagram showing how the final mixture 10001 in the cylinder is administered by pushing out the plunger rod 8005 by the user.

Here, the final mixture is administered as it is, but a method may be used in which a solvent such as water is injected into the cylinder while the final mixture is contained in the cylinder to make a solution, and then the administration is performed.

By providing a dosing machine incorporating the above-mentioned metering / mixing machine, an individual can easily self-adjust and administer the drug necessary for his / her own drug treatment by using an intermediate stick that is easy to handle. It becomes possible.

The present invention is applicable in the pharmaceutical industry, the dispensing industry, the cosmetics industry, the cooking industry or the painting industry. It is also applicable in the production process of various factories.

1001a Magazine 1002a Intermediate Stick 1003 Weighing Mixer 1010 Locking Machine
1011 Liquid generator 1012 Packing machine

Claims (9)

Using a plurality of types of stick intermediates having a uniform active ingredient per length, which are previously produced by a stick intermediate manufacturer in the form of a rod having a predetermined diameter or cross-sectional area by mixing the necessary additives for the active ingredient. A system for dispensing or self-adjusting drugs necessary for drug treatment .
A system comprising a metering mixer that weighs and cuts and separates the length of each of the stick intermediates to produce the final mixture of the intended formulation. The first aspect of claim 1, wherein the plurality of types of stick intermediates include stick intermediates having the same type of active ingredient but different cross-sectional areas or uniform concentrations. system. The system according to claim 1, wherein the stick intermediate has a shape of an end portion that is not used, depending on the type or size of the active ingredient. The system according to claim 1, wherein the additive is at least one selected from a base solvent, a binder, a lubricant, and a pH adjuster. The system according to claim 1, wherein the stick intermediate is coated. The system according to claim 1, further comprising a magazine in which a plurality of the stick intermediates can be stored, which is used for supplying and distributing the stick intermediate. In the system of claim 1, a) a tableting means for producing the final mixture and then mixing and tableting the necessary additives, and b) producing the final mixture and then mixing the necessary additives. 1. The system according to claim 1, further comprising at least one selected from the packaging means for producing the final mixture and then packaging the liquid. The system according to claim 1, wherein the metering mixer can use a stick intermediate in which the cross-sectional area of the cross section is increased or decreased according to the required amount of a raw material as an active ingredient. The system according to claim 1, wherein the system includes an automatic dispensing machine adapted for individual drug treatment, and the metering / mixing machine is incorporated in the automatic dispensing machine.

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