JP6944685B2 - Usage history detection method of bio-applied light irradiation device and bio-applied light irradiation device - Google Patents

Description

The present invention relates to a method for detecting the usage history of a bioapplied light irradiation device for detecting whether the bioapplied light irradiation device is unused or used, and a bioapplied light irradiation device.

Light can be used to treat a wide variety of diseases. When light is used alone to treat a disease, this treatment is called phototherapy. When light is used with pharmacy, this treatment is called photodynamic therapy (PDT). These therapies can be used to treat a variety of skin and internal disorders.
Also in the beauty field, a method of removing acne, unnecessary stains, wrinkles, etc. by irradiating them with light rays is known.
Such phototherapy was generally performed in hospitals and beauty facilities using a large-scale light irradiation device. Many such large-scale light irradiation devices have not been installed even in hospitals and beauty facilities. Therefore, due to traffic conditions and the influence of congestion of facilities and equipment, patients and users who desire light irradiation cannot easily irradiate light at the desired timing, which is extremely inconvenient. In addition, it was not possible to satisfy the user's fundamental desire to easily irradiate light at home or on the go without the help of medical technicians and beauty technicians.
On the other hand, in recent years, disposable therapeutic devices for phototherapy have been known (see Patent Documents 1 to 3). Patent Document 1 describes a disposable portable device using an organic semiconductor as a light source. Patent Document 1 describes a portable device using an organic EL element having a light emitting layer formed on a glass substrate. Patent Document 2 describes a luminescent medical device capable of transmitting light to the surface of a patient's skin as a disposable skin care device. Patent Document 3 describes a device that uses an organic light emitting device as a light source to enhance the penetration and action of a pharmaceutical or cosmetic active ingredient into the skin.

Patent No. 4651281 Special Table 2013-532503 Special Table 2013-532497

By the way, when phototherapy is performed using a device (bioapplied light irradiation device) that is applied to a living body and irradiates light in this way, the light emitting surface of the bioapplied light irradiation device is usually applied to the affected area to which the photosensitizer is applied. Treatment is performed by contacting the (living body application surface) and irradiating the affected area with light for a certain period of time. In this way, since the bioapplying light irradiation device is used by bringing the light emitting surface into contact with the affected part, the skin keratin, secretions, and drugs that have fallen off from the affected part adhere to the bioapplying surface and are contaminated. .. Therefore, from the viewpoint of maintaining the therapeutic effect and hygiene, it is desirable to dispose of the bioapplied light irradiation device after use without reusing it.
However, conventional bio-applied light irradiation devices cannot be discriminated at a glance as to whether or not they have been used, and are repeatedly used without knowing that they have been used, and stains accumulate to have a therapeutic effect. There was a problem that was damaged.

The problem to be solved by the present invention is to provide a method for detecting the usage history of a biologically applicable light irradiation device and a biologically applicable light irradiation device capable of detecting the usage history of the biologically applicable light irradiation device, and further, a disposable type. Incorrect use of a bio-applicable light irradiation device that has been used, or a bio-applicable light irradiation device for which the permissible range of the number of times of use or the usage time is set and exceeds the permissible range is to be mistakenly used. It is an object of the present invention to provide a biologically applicable light irradiation device that can be reliably avoided.

As a result of diligent studies by the present inventors in order to solve the above problems, an ID unique to the bioapplied light irradiation device is set, and the usage history is stored in the storage unit for each ID. Before driving the bioapplied light irradiation device, it is determined whether or not the bioapplied light irradiation device has been used by searching whether or not the usage history is stored in the storage unit using the ID as an identification code. We found that it could be detected. In addition, by controlling the power on / off state based on the usage history information, it is a disposable type biological application light irradiation device that has been used, or a biological application in which the allowable range of the number of times of use or the usage time is set. It has been found that light irradiation devices that exceed the permissible range can be reliably avoided from being used incorrectly.
The present invention, which is a specific means for solving the above problems, and preferred embodiments of the present invention are as follows.
[1] An ID transmission unit that is attached to a bioapplicable light irradiation device to which a unique ID is set and transmits ID information corresponding to the ID set in the bioapplyable light irradiation device, and an ID transmission unit that transmits the ID information. A communication unit that receives incoming ID information, and a storage unit that stores usage history information of one or more bioapplied light irradiation devices for each device in correspondence with a unique ID set for each bioapplied light irradiation device. , The control unit uses a control unit that reads out the ID information received by the communication unit and searches for the usage history information stored corresponding to the same ID as the ID information from the usage history information stored in the storage unit. A method for detecting the usage history of a bioapplied light irradiation device that detects the usage history of a bioapplied light irradiation device in which a unique ID is set based on the search result of the usage history information and the usage history information found by the search.
[2] An ID transmitter that is attached to a bioapplied light irradiation device in which a unique ID is set and the bioapplied light irradiation device and transmits ID information corresponding to the ID set in the bioapplied light irradiation device. A bio-applied light irradiation device with an ID transmitter and a controller for controlling the drive of the bio-applied light irradiation device are provided, and the controller includes a communication unit that receives ID information transmitted from the ID transmitter and one. A storage unit that stores the usage history information of the above bio-applied light irradiation device for each device corresponding to the unique ID set for each bio-applied light irradiation device, and a storage unit that reads out the ID information received by the communication unit and stores it. A control unit that searches for usage history information stored corresponding to the same ID as the ID information from the usage history information stored in, and a display unit that displays usage history information found by the search in the control unit. , A bioapplied light irradiator having a power source that supplies power to a bioapplied light irradiating device with an ID transmitter (power is supplied when the power is on and no electrodes are supplied when the power is off).
[3] An ID transmitter that is attached to a bioapplied light irradiation device in which a unique ID is set and the bioapplied light irradiation device and transmits ID information corresponding to the ID set in the bioapplyable light irradiation device. A bio-applied light irradiation device with an ID transmitter and a controller for controlling the drive of the bio-applied light irradiation device are provided, and the controller includes a communication unit that receives ID information transmitted from the ID transmitter and one. A storage unit that stores the usage history information of the above bioapplicable light irradiation devices corresponding to the unique ID set for each bioapplicable light irradiation device for each device, and the bioapplicable light irradiation device for which the unique ID is set. (Power is supplied when the power is on and electrodes are not supplied when the power is off) and the ID information received by the communication unit is read out and stored in the storage unit. Bioapplied light having a control unit that searches the usage history information stored corresponding to the same ID as the ID information from the history information and controls the power on / off state based on the search result of the usage history information. Irradiation device.
[4] The biologically applicable light irradiation device according to [3] preferably has a controller further including a display unit that displays a search result by the control unit and usage history information found by the search.
[5] When the bioapplied light irradiation device control unit according to [3] or [4] finds the usage history information stored corresponding to the same ID as the ID information as a result of the search for the usage history information, It is preferable to control the power supply so that it does not turn on.
[6] In the biologically applicable light irradiation device according to any one of [2] to [5], the ID transmitting unit has a power source generating unit, and the power source is generated by the power generation unit, whereby the living body is living. It is preferable that the ID information set in the applicable light irradiation device is transmitted.
[7] In the bioapplicable light irradiation device according to [6], the bioapplicable light irradiation device in which unique ID information is set and the power generation unit are electrically connected and connected to one end. It is preferable that the power source is generated by the power source generation unit by having a conducting wire in which the terminals are formed and the connection terminals are electrically connected to the power source.
[8] In the biologically applicable light irradiation device according to any one of [2] to [5], it is preferable that the ID transmission unit is an RFID tag and the communication unit is an RFID reader unit.
[9] The biologically applicable light irradiation device according to any one of [2] to [8] has a function in which the control unit writes an ID corresponding to the ID information read from the communication unit to the storage unit, and the ID. It is preferable to have a function of writing the usage history information of the bioapplied light irradiation device having the unique ID in the storage unit in correspondence with the ID.
[10] In the bioapplied light irradiation device according to any one of [2] to [9], the controller further has an input operation unit for performing an input operation by the user, and the control unit is the user. It is preferable to have a function of writing to the storage unit as usage history information that the input operation has been performed on the input operation unit.
[11] It is preferable that the bioapplied light irradiation device according to any one of [2] to [10] has a clock function unit in which the controller further measures the time and outputs the time to the control unit.
[12] The biologically applicable light irradiation device according to any one of [2] to [11] is a biological body in which a controller, a power supply line electrically connected to a power source, and a unique ID are set. It has a device connection detection unit that detects that the applicable light irradiation device is connected to the power supply line, and the control unit reads ID information from the communication unit on condition that the device connection detection unit detects the connection. Is preferable.
[13] In the biologically applicable light irradiation device according to [12], it is preferable that the device connection detection unit is electrically connected to the power supply line.
[14] The bioapplied light irradiation device according to [12] or [13] further has a conducting wire electrically connected to the bioapplied light irradiation device in which a unique ID is set, and is a device connection detection unit. However, it is preferable to detect that the lead wire is connected to the power supply line.
[15] In the bioapplying light irradiation device according to [14], the ID transmitting unit has a power source generating unit, and the power source is generated by the power generation unit, so that the ID set in the bioapplied light irradiation device is set. Information is transmitted, and it is preferable that the power generation unit is electrically connected to the conducting wire.
[16] In the bioapplying light irradiation device according to any one of [2] to [15], it is preferable that the bioapplying light irradiation device has a substrate and a light emitting element provided on the substrate.
[17] In the bioapplied light irradiation device according to [16], it is preferable that the light emitting element includes an organic semiconductor or quantum dots.
[18] In the bioapplied light irradiation device according to [17], it is preferable that the light emitting element is an organic electroluminescence element containing an organic semiconductor.

According to the method for detecting the usage history of the bioapplied light irradiation device and the bioapplied light irradiation device of the present invention, it is possible to detect the usage history of the bioapplied light irradiation device before driving. Furthermore, a disposable type bioapplied light irradiation device that has been used, or a bioapplied light irradiation device that has a permissible range of the number of times of use or usage time and exceeds the permissible range is erroneously selected. It can be surely avoided to use it.

It is a block diagram which shows 1st Embodiment of the bioapplied light irradiation apparatus of this invention. It is a block diagram which shows the 2nd Embodiment of the bioapplied light irradiation apparatus of this invention. It is the schematic which shows an example of the connection structure of a controller and a living body application light irradiation device. It is a schematic cross-sectional view which shows an example of the bioapplied light irradiation device used in this invention. It is a schematic cross-sectional view which shows an example of the light emitting chemical cells (LEC) type light emitting body layer of the bioapplied light irradiation device used in this invention.

Hereinafter, the present invention will be described. The description of the constituent elements described below may be based on typical embodiments and specific examples of the present invention, but the present invention is not limited to such embodiments and specific examples. The numerical range represented by using "~" in the present specification means a range including the numerical values before and after "~" as the lower limit value and the upper limit value.

The method for detecting the usage history of the bioapplied light irradiation device of the present invention and the bioapplied light irradiation device used in the bioapplied light irradiation device of the present invention have a substrate and a light emitting element provided on the substrate, and the light emitting element of the substrate and the light emitting element of the substrate. It emits light from the opposite surface. The light emitting element emits light to the substrate side by supplying electric power, and the substrate is a transparent substrate having translucency with respect to the light emitted by the light emitting element. In this substrate, the surface on the side that emits light (the surface on the side opposite to the light emitting element) constitutes a biological application surface that is directed to the biological side of the object to be irradiated with light.
In order to treat a living body with a bioapplied light irradiation device, electric power is supplied to a light emitting element to radiate light in a state where the bioapplying surface of the bioapplied light irradiation device is in contact with or close to the living body. As a result, the living body is irradiated with the light from the light emitting element, and the phototherapy effect and the beauty effect are exhibited. A detailed description of the bioapplied light irradiation device will be described later.

<Method of detecting usage history of biologically applicable light irradiation device>
The method for detecting the usage history of the bioapplied light irradiation device of the present invention is attached to the bioapplied light irradiation device in which a unique ID is set, and transmits ID information corresponding to the ID set in the bioapplied light irradiation device. ID transmission unit, communication unit that receives ID information transmitted from the ID transmission unit, and unique ID set for each bioapplied light irradiation device with usage history information of one or more bioapplied light irradiation devices. The usage history stored corresponding to the same ID as the ID information from the usage history information stored in the storage unit by reading the ID information received by the communication unit and the storage unit stored for each device corresponding to the above. A method of detecting the usage history of a bioapplied light irradiation device with a unique ID set based on the search result of the usage history information by the control unit and the usage history information found by the search using the control unit that searches for information. be.
In the present invention, the "unique ID" is an ID individually set in the bioapplied light irradiation device 70, and refers to a code for individually identifying the bioapplied light irradiation device 6.
In the present invention, the transmission of ID information from the ID transmission unit to the communication unit may be by wired communication or wireless communication.
In the present invention, the "use history information of the bioapplied light irradiation device" is a fact indicating that the bioapplied light irradiation device has been used. As the usage history information, for example, there was an operation of the input operation unit (irradiation time setting, user registration, on / off switching operation of the bioapplied light irradiation device, etc.) for the bioapplied light irradiation device, and bioapplied light irradiation from the power source. The fact that power has been supplied to the device, the number of times power has been supplied, the power supply time for each time, the cumulative power supply time, etc. can be mentioned, and it can be set appropriately according to the usage status of the biologically applicable light irradiation device. can.
In the present invention, "detecting the usage history of the bioapplied light irradiation device for which the ID is set based on the search result of the usage history information by the control unit and the usage history information found by the search" is defined by, for example, the control unit. As a result of searching the usage history information, if the usage history information corresponding to the same ID as the ID information read from the communication unit is not found, the bioapplicable light irradiation device in which the ID is set is unused. When the usage history information corresponding to the same ID as the ID information is found, it is known that the bioapplicable light irradiation device in which the ID is set has been used. Further, from the contents of the usage history information, the number of times of use and the usage time of the bioapplicable light irradiation device for which the ID is set are detected. The number of times the bioapplied light irradiation device has been used can be detected from the number of times power is supplied to the bioapplied light irradiation device, and the usage time of the bioapplied light irradiation device is detected from the cumulative power supply time to the bioapplied light irradiation device. be able to. In addition, the search result of the usage history information and the usage history information found by the search can be notified to the user, for example, by displaying the contents on the display unit or by sounding a warning sound when the usage history information has been used. can.

As described above, in this method of detecting the usage history of the bioapplied light irradiation device, the usage history of the bioapplied light irradiation device in which a unique ID is set from the usage history information stored for each device corresponding to the ID. The information is searched, and the usage history of the bioapplied light irradiation device for which the ID is set is detected based on the search result and the usage history information found by the search. By detecting the usage history in the bioapplied light irradiation device before driving, for example, in the case of a disposable type bioapplyable light irradiation device, it is possible to avoid accidentally using the used one. In the case of a biologically applicable light irradiation device in which the allowable range of the number of times of use and the allowable range of use time is set, it is possible to avoid erroneously using the biologically applicable light irradiation device exceeding the allowable range. As a result, only the bioapplied light irradiation device having good performance and hygiene can be used, and the phototherapy effect and the beauty effect can be sufficiently obtained.

<Biologically applicable light irradiation device>
Next, the biologically applicable light irradiation device of the present invention will be described.
The bioapplied light irradiation device of the present invention is attached to a bioapplied light irradiation device in which a unique ID is set and the bioapplied light irradiation device, and has an ID corresponding to the ID set in the bioapplied light irradiation device. A biologically applicable light irradiation device with an ID transmitter having an ID transmitter for transmitting information and a controller for controlling the drive of the biologically applicable light irradiation device are provided, and the controller receives ID information transmitted from the ID transmitter. Received by the communication unit, the storage unit that stores the usage history information of one or more bioapplicable light irradiation devices for each device corresponding to the unique ID set for each bioapplicable light irradiation device, and the communication unit. A control unit that reads ID information and searches for usage history information stored corresponding to the same ID as the ID information from the usage history information stored in the storage unit, and a usage history found by the search in the control unit. It has a display unit for displaying information and a power source for supplying power to a biologically applicable light irradiation device with an ID transmission unit when it is in the ON state.
Alternatively, the bioapplied light irradiation device of the present invention corresponds to a bioapplied light irradiation device in which a unique ID is set and an ID set in the bioapplied light irradiation device, which is attached to the bioapplied light irradiation device. A biologically applicable light irradiation device with an ID transmitting unit having an ID transmitting unit for transmitting ID information to be used, and a controller for controlling the driving of the biologically applicable light irradiation device, the controller is provided with ID information transmitted from the ID transmitting unit. A communication unit that receives At one time, the power supply that supplies power to the biometric light irradiation device for which a unique ID is set, and the ID information received by the communication unit are read out, and the same as the ID information from the usage history information stored in the storage unit. It has a control unit that searches for usage history information stored corresponding to the ID and controls the on / off state of the power supply based on the search result of the usage history information.
For the definition of [unique ID], the description and specific examples of "use history information of the bioapplied light irradiation device", the description in the section of "usage history detection method of the bioapplied light irradiation device" can be referred to.
"Controlling the power on / off state based on the search result of the usage history information" performed by the control unit means, for example, the same ID as the ID information read from the communication unit as a result of the search of the usage history information by the control unit. When the corresponding usage history information is found, the power is not turned on until the ID information is no longer received, or the number of times the bioapplied light irradiation device with the ID is set has been used. If the usage time exceeds the set permissible range, the power is not turned on until the ID information is no longer received, and the bioapplicable light irradiation device is required. It can be set as appropriate according to the usage mode.
Hereinafter, embodiments of the biologically applicable light irradiation device of the present invention will be described.

[First Embodiment of Biologically Applicable Light Irradiation Device]
First, a first embodiment of a biologically applicable light irradiation device will be described.
FIG. 1 is a block diagram showing a configuration of a biologically applicable light irradiation device according to the first embodiment. For the biologically applicable light irradiation device 70, a top view (upper view) and a side view (lower view) are schematically shown. It is shown in. The arrows in the side view indicate the direction of light emission.
The biologically applicable light irradiation device shown in FIG. 1 includes a biologically applicable light irradiation device 10 with an ID transmitter and a controller 20 that controls the drive of the biologically applicable light irradiation device.

The bioapplicable light irradiation device 10 with an ID transmission unit is configured by attaching an ID transmission unit 40, a power cable (conductor) 50a, and a communication cable 60a to the bioapplyable light irradiation device 70. The configuration of the biologically applicable light irradiation device 70 will be described in detail later. The ID transmission unit 40 may be attached to the upper surface of the biological application light irradiation device 70 or the like as a separate member from the biological application light irradiation device 70, or the ID transmission unit 40 may be attached to the transparent substrate of the biological application light irradiation device 70. The organic transistor or organic memory constituting the above may be formed and integrally attached to the bioapplied light irradiation device.
The power cable 50a is electrically connected to the electrode of the biologically applicable light irradiation device 70 and the power generation unit 44 of the ID transmission unit 40, and one end thereof is connected to the power cable connection unit 50b of the controller 20. The terminals are formed. Further, the communication cable 60a is connected to the first communication unit 43 of the ID transmission unit 40, and a connection terminal connected to the communication cable connection unit 60b of the controller 20 is formed at one end of the communication cable 60a. The power cable 50a is composed of a conducting wire. As the communication cable 60a, a wire material capable of information communication can be used, and for example, a conducting wire, an optical fiber, or the like can be used. Further, the communication between the first communication unit 43 and the second communication unit 21 may be performed by wireless communication without using the communication cable 60a.

The ID transmission unit 40 includes a control unit 41, a first storage unit 42, a first communication unit 43, and a power generation unit 44 that generates a power source for supplying electric power to each of these units, and is a biologically applicable light irradiation device 70. It is configured to transmit the ID information corresponding to the unique ID set in the controller 20 to the controller 20. Further, the first storage unit 42 is composed of a non-volatile memory that retains storage without supplying electric power. Examples of the non-volatile memory include a ROM, a flash memory, a magnetic storage device, an optical disk, and the like.
In the ID transmission unit 40, when the ID information is input to the first control unit 41 at the time of manufacturing the biologically applicable light irradiation device 10 with the ID transmission unit, the first control unit 41 writes the ID information to the first storage unit 42. .. After that, when the power cable 50a is connected to the power cable connection unit 50b of the controller 20, power is generated in the power generation unit 44, the operation of each unit constituting the ID transmission unit 40 is turned on, and the first storage unit The control unit 41 reads out the ID information stored in the 42 and transmits it to the first communication unit 43. Further, when the connection cable 60a is connected to the connection cable connection unit 60b of the controller 20, the first communication unit 43 transmits the ID information to the second communication unit 21 of the controller 20.

The controller 20 has the following functions.
(1) Connection detection function for detecting that the power cable 50a is physically and electrically connected to the power cable connection terminal 50b (2) The control unit 41 and the first storage unit 42 of the ID transmission unit 40, Communication functions for transmitting and receiving information to and from the controller control unit 25 of the controller 20 (second communication unit 21, first communication unit 43),
(3) A function of reading the ID information of the bioapplied light irradiation device 70 transmitted from the ID transmission unit 40 on condition that it is detected that the power cable 50a is connected to the power cable connection terminal 50b (4). ) A function of recording a plurality of ID information of the bioapplied light irradiation device 70 transmitted from the ID transmission unit 40 in the second storage unit 26 and reading them arbitrarily, a data processing function, and a processing data display control function (5) ID. A function to record, hold, read, and display information and the irradiation start time, irradiation end time, irradiation time, and usage history of each of a plurality of controller users of the bioapplied light irradiation device 70 that corresponds one-to-one with its ID. Usage history management function (6) After reading the ID information of the bioapplied light irradiation device 70 transmitted from the ID transmission unit 40, a predetermined operation (irradiation time setting, user registration, on / off switching of the bioapplied light irradiation device) Etc.), the fact that the operation was performed is recorded as usage history information in the second storage unit 26 corresponding to the read ID, and thereafter, the power cable of the bioapplicable light irradiation device having the same ID. Function that does not turn on the drive of the bioapplicable light irradiation device when is connected These functions are performed by the operation of each part constituting the controller 20. Hereinafter, the configuration and operation of each part constituting the controller 20 will be described.

The controller 20 includes a second communication unit (communication unit) 21, an input operation unit 22, an input unit 23, a clock function unit 24, a controller control unit 25, a second storage unit (storage unit) 26, a display unit 27, and a drive circuit ( It has a power supply) 28, an on / off switching unit 29, a device connection detection unit 30, a power cable connection unit 50b to which the power cable 50a and the communication cable 60a are connected, and a communication cable connection unit 60b, respectively.

The second communication unit 21 is connected to the communication cable connection unit 60b. When the communication cable 60a is connected to the communication cable connection unit 60b, the second communication unit 21 is in a state of receiving the ID information transmitted from the first communication unit 43 of the ID transmission unit 40.

The input operation unit 22 is composed of an instrument or device for performing an input operation by the user. Examples of the device or the like on which the user performs an input operation include a push button, an operation lever, a keyboard, a mouse, and the like. Further, as the input operation performed by the user, an on / off switching operation of the drive circuit 28, an on / off switching operation of the biologically applicable light irradiation device 70, a light irradiation time and brightness setting operation, a user registration operation, and the like can be mentioned. .. The input operation performed by the input operation unit 22 is converted into an input signal by the input unit 23 and output to the controller control unit 25. Further, in the embodiment of the bioapplied light irradiation device, the fact that the user has performed the above input operation is stored in the second storage unit 26 for each ID of the bioapplied light irradiation device as "usage history information". It is also used to detect the usage history of biologically applicable light irradiation devices and to control drive circuits. The detection of the usage history and the control of the drive circuit will be described in the section "Detection of the usage history and control of the drive circuit" below.

The clock function unit 24 has a function of measuring the time, and outputs the measured time to the controller control unit 25 in response to a request from the controller control unit 25.

The second storage unit 26 is composed of a non-volatile memory, and is configured to be able to store connection detection information, usage history information, and other information for each ID of the bioapplied light irradiation device 6. Other information includes the user name of the controller, the light irradiation start time, the light irradiation end time, the light irradiation time, and the like. These pieces of information are written by the controller control unit 25 in the second storage unit 26, appropriately read from the second storage unit 26, and displayed on the display unit 30. For a specific example of the non-volatile memory used in the second storage unit 26, a specific example of the non-volatile memory used in the first storage unit 42 of the ID transmission unit 40 can be referred to.

The display unit 27 displays the information transmitted from the controller control unit 25 according to the instruction of the controller control unit 25. The information displayed on the display unit 27 is at least the usage history information of the biologically applicable light irradiation device 70, and the usage history information can be displayed for each user of the controller 20. Other information displayed by the display unit 30 includes irradiation start time, irradiation end time, irradiation time, remaining wearing time, input items input to the input operation unit, and the like.

The drive circuit 28 is electrically connected to the power cable connection portion 50b via the power supply line 50c. When the power cable 50a is connected to the power cable connection portion 50b, the drive circuit 28 is electrically connected to the bioapplied light irradiation device 70 and the current generation unit 44 via the power cable 50a and the power line 50c, and the living body It is in a state where it can function as a power source for supplying electric power to the applicable light irradiation device 70.

The on / off switching unit 29 switches the on / off state of the drive circuit 28 according to the instruction of the controller control unit 25. Even if the power cable 50a is connected to the power cable connection portion 50b, when the drive circuit 28 is in the off state, the drive circuit 28 does not supply power to the biologically applicable light irradiation device 70. When the drive circuit 28 is switched to the on state, electric power is supplied from the drive circuit 28 to the biological application light irradiation device 70, and light is emitted from the biological application surface of the biological application light irradiation device 70. That is, the on-state and the off-state of the drive circuit 28 correspond to the on-state and the off-state of the biologically-applied light irradiation device 70, respectively.

The device connection detection unit 30 is connected in the middle of the power supply line 50c, detects that the power cable 50a is physically and electrically connected to the power cable connection unit 50b, and detects that information (connection detection information). ) Is output to the controller control unit 25.

The controller control unit 25 performs data processing, controls of each unit, and a second storage unit according to ID information from the second communication unit 21, an input signal from the input unit 23, connection detection information from the device connection detection unit 30, and the like. Information is written / read to 26. Further, it plays a central role in detecting the usage history of the biologically applicable light irradiation device 70 and controlling the drive circuit 28 based on the usage history. Hereinafter, the procedure for detecting the usage history and controlling the drive circuit 28 based on the usage history will be described.

(Detection of usage history of biologically applicable light irradiation device and control of drive circuit based on usage history)
First, when the power cable 50a is connected to the power cable connection unit 50b of the controller 20, the device connection detection unit 30 outputs the connection detection information to the controller control unit 25. When the communication cable 60a is connected to the communication cable connection unit 60b of the controller 20, the second communication unit 21 receives the ID information transmitted from the first communication unit 43 of the ID transmission unit 40.
When the connection detection information is input from the device connection detection unit 30, the controller control unit 25 reads out the ID information received by the second communication unit 21, and stores the ID information in the second storage unit 26. The same ID is searched by collating with the ID. If the same ID as the ID information is not yet stored in the second storage unit 26, the controller control unit 25 newly writes the ID information in the second storage unit 26 and detects the connection corresponding to the ID. Information is written in the second storage unit 26. After that, if an input signal is input from the input unit 23 before the next connection detection information is input, the controller control unit 25 gives an instruction according to the input signal to the on / off switching unit 29 or the display unit 27. Etc., and the fact that there was an input operation in the input operation unit 22 (usage history information) is written in the second storage unit 26 in correspondence with the newly written ID.
Further, when the same ID as the ID information read from the second communication unit 21 is already stored in the second storage unit 26, the controller control unit 25 stores the usage history information corresponding to the ID in the second storage unit 26. It is determined whether or not the information is stored in the 26, and if the usage history information is not stored, the connection detection information is written in the second storage unit 26 in correspondence with the ID. After that, if an input signal is input from the input unit 23 before the next connection detection information is input, the controller control unit 25 gives an instruction according to the input signal to the on / off switching unit 29 or the display unit 27. Etc., and the fact that there was an input operation in the input operation unit 22 (usage history information) is written in the second storage unit 26 in correspondence with the ID read from the second communication unit 21.
In these cases, for example, when the input signal from the input unit 23 is a signal for turning on the drive of the bioapplied light irradiation device 6, the on / off switching unit 29 turns on the drive circuit 28 according to the instruction of the controller control unit 25. Switch to the state. As a result, electric power is supplied from the drive circuit 28 to the biologically applicable light irradiation device 70, and light is radiated from the biologically applicable surface. In other words, the biologically applicable light irradiation device 70 in these cases is in an operable state that can be driven by an input operation to the input operation unit 22.
On the other hand, when the usage history information corresponding to the ID read from the second communication unit 21 is already stored in the second storage unit 26, the controller control unit 25 displays the usage history information corresponding to the ID. Output to 27. In this case, even if an input signal for turning on the biologically applicable light irradiation device 6 is further input from the input unit 23, the controller control unit 25 does not output an instruction corresponding to the input signal to the on / off switching unit 29 and drives the device. The circuit 28 is controlled to be kept in the off state. As a result, the biologically applicable light irradiation device 6 is in an inoperable state in which it is not driven even if the input operation unit 22 is operated.

(Overall operation of bioapplied light irradiation device)
Next, the overall operation of this bioapplied light irradiation device will be described.
In this bioapplicable light irradiation device, the connection terminals of the power cable 50a and the communication cable 60a of the bioapplicable light irradiation device 70 with an ID transmitter are connected to the power cable connection 50b and the communication cable connection 60b of the controller 20, respectively. When connected, if the bioapplied light irradiation device 70 has not been connected and the input operation unit 22 has not been operated before, that is, if the bioapplied light irradiation device 70 has no usage history, the bioapplied light The irradiation device 70 is in an operable state, and by performing an operation of turning on the drive of the biological application light irradiation device 6 to the input operation unit 22, power is supplied to the biological application light irradiation device 70 and light is emitted from the biological application surface. Is radiated.
On the other hand, when the bioapplied light irradiation device 70 has a usage history, the usage history information is displayed on the display unit 27. As a result, the user can know that the biologically applicable light irradiation device 70 has been used. Further, in this case, the biologically applicable light irradiation device 70 is in an inoperable state, and even if the input operation unit 22 is operated to turn on the drive of the biologically applicable light irradiation device 70, the biologically applicable light irradiation device 70 is still in operation. No power is supplied and no light is emitted from the bioapplicable surface.
By the above operation, in this bioapplied light irradiation device, the used bioapplied light irradiation device is not accidentally used, and the usage history information displayed on the display unit is used as a clue to indicate that the used bioapplied light irradiation device has been used. The detected bioapplicable light irradiation device with an ID transmitter can be replaced with a new bioapplicable light irradiation device with an ID transmitter. Therefore, only a biologically applicable light irradiation device having good performance and hygiene can be used, and the phototherapy effect and the beauty effect can be sufficiently obtained.

[Second Embodiment of Biologically Applicable Light Irradiation Device]
Next, a bioapplied light irradiation device (second embodiment) to which the second embodiment of the usage history detection method of the bioapplied light irradiation device is applied will be described.
FIG. 2 is a block diagram showing the configuration of the bioapplicable light irradiation device of the second embodiment, and the bioapplyable light irradiation device 70 and the RFID tag 80 are a top view (upper view) and a side view (lower view). ) Is schematically shown. The arrows in the side view indicate the direction of light emission.
This bioapplicable light irradiation device has an RFID tag 80 instead of the ID transmission unit 40, an RFID reader unit 90 instead of the second communication unit 21, and has a communication cable 60a and a communication cable connection unit 60b. The configuration is the same as that of the bioapplied light irradiation device shown in FIG. 1, except that it is not used.

The RFID tag 80 is composed of an antenna, a communication unit, a control unit, a storage unit, and the like. The control unit reads out the ID information stored in the storage unit, and the communication unit carries the ID information on the modulated wave (radio wave). Can be generated and transmitted from the antenna. Here, the ID information stored in the storage unit is the ID information corresponding to the unique ID set in the bioapplied light irradiation device 70. As shown in FIG. 2, the RFID tag 80 may be attached to the upper surface of the bioapplicable light irradiation device 70 or the like as a separate member from the bioapplicable light irradiation device 70, or may be attached to a transparent substrate of the bioapplicable light irradiation device. An organic transistor or an organic memory constituting an RFID tag may be formed on the device and integrally attached to a bioapplied light irradiation device.

The RFID reader unit 90 includes an antenna 91, a communication unit 92, a control unit 93, and an interface unit 94.
The antenna 91 transmits and receives radio waves to and from the antenna of the RFID tag 80.
The communication unit 92 has a function of demodulating radio waves received by the antenna, extracting information, and outputting the information to the control unit 93, and the information input from the control unit 93 is placed on a carrier wave to create a modulated wave and output to the antenna 91. Has the function of
The interface unit 94 is connected to the controller control unit 25, transmits and receives information to and from the controller control unit 95, and outputs the received information to the control unit 93.
When the control unit 93 receives the ID information read command from the controller control unit 25 via the interface unit 94, the control unit 93 reads the ID information demodulated by the communication unit 92 and transmits it to the controller control unit 95 via the interface unit 84. do.

The operation of each unit other than the RFID tag 80 and the RFID reader unit 90 of this biologically applicable light irradiation device is that the controller control unit 25 reads the ID information from the RFID reader unit 8 instead of reading the ID information from the second communication unit 21. Other than that, it is the same as that of the first embodiment.
The biologically applicable light irradiation device of the second embodiment can also obtain the same effects as those of the biologically applicable light irradiation device of the first embodiment.
Further, in the second embodiment, since the communication cable 60a and the communication cable connection terminal 60b are not required, the effect that the configuration of the biologically applicable light irradiation device can be simplified can be obtained.

[Third Embodiment of a biologically applicable light irradiation device]
The biologically applicable light irradiation device of the third embodiment is used in combination with a mobile phone terminal capable of displaying an image such as a smartphone, and is carried instead of the input operation unit 22, the input unit 23, and the display unit 27. It has the same configuration as the biologically applicable light irradiation device of the first embodiment and the second embodiment except that it has a communication function for transmitting and receiving information to and from a telephone terminal.
As the communication function, for example, a Bluetooth (registered trademark) communication function can be used. Information transmission / reception performed by the communication function includes transmission of a program that imparts the same functions as the input operation unit 22, the input unit 23, and the display unit 27 to the mobile phone terminal in the first embodiment and the second embodiment, and the mobile phone terminal. The transmission of display information to the display unit of the mobile phone, the reception of an input signal from a mobile phone terminal, and the like can be mentioned.
The operation of each part of the bioapplied light irradiation device is that the controller control unit 25 operates based on the input signal received from the mobile phone terminal instead of the input signal from the input unit 23, and the controller control unit 25 operates. , The same as the first embodiment and the second embodiment except that the display information such as the usage history information is transmitted to the mobile phone terminal via the communication function instead of being output to the display unit 27.
The biologically applicable light irradiation device of the fifth embodiment can also obtain the same effects as those of the biologically applicable light irradiation devices of the first embodiment and the second embodiment.
Further, in the third embodiment, in particular, by input operation to the mobile phone terminal, it is possible to switch the drive circuit on / off, switch the bioapplied light irradiation device on / off, set the brightness, and the like, and use history information and Since information such as the remaining wearing time can be displayed on the display screen of the mobile phone terminal, the input operation unit 22, the input unit 23, and the display unit 27 are not required on the biologically applicable light irradiation device side. Therefore, the effect that the configuration of the biologically applicable light irradiation device can be extremely simplified can be obtained.

Although the embodiment of the bioapplicable light irradiation device of the present invention has been described above, the configuration of the bioapplicable light irradiation device of the present invention is not limited to each of the above embodiments. For example, in the bioapplicable light irradiation devices of the first to third embodiments, the drive circuit 28 and the bioapplicable light irradiation device are formed by connecting the power cable 50a to the power cable connection portion 50b formed in the controller 2. 70 is electrically connected, but as shown in FIG. 3, a power cable 104 electrically connected to the power line 50c is provided, and the power cable 104 and the power cable 50a are connected by an intermediate connector 102 for driving. The circuit 28 and the bioapplied light irradiation device 70 may be electrically connected.

<Biologically applicable light irradiation device>
Next, the method for detecting the usage history of the bioapplied light irradiation device of the present invention and the bioapplied light irradiation device used in the bioapplied light irradiation device of the present invention will be described.
The biologically applicable light irradiation device used in the present invention has a substrate and a light emitting element provided on the substrate. In the bioapplied light irradiation device, the substrate is preferably a flexible substrate, the light emitting element preferably contains an organic semiconductor or quantum dots, and more preferably the light emitting element contains an organic semiconductor.

FIG. 4 shows a specific example of the layer structure of the biologically applicable light irradiation device.
In FIG. 4, 202 represents a substrate and 217 represents a light emitting element, respectively. Here, in the following description, the surface of the substrate 202 on the side where the light emitting element 217 is provided is referred to as a "light emitting element forming surface", and the surface of the substrate 202 opposite to the light emitting element forming surface is referred to as a "biologically applicable surface". ". The biologically applicable light irradiation device shown in FIG. 4 is applied to the living body with the living body applied surface facing the living body. Further, in this biologically applicable light irradiation device, the light emitting element has a layered shape, and the light emitting layer 207 of the light emitting element 217 serves as a surface light source. Here, among the biologically applicable surfaces of the substrate 202, the region obtained by projecting the light emitting layer 207 onto the substrate is referred to as "light emitting unit 218".
Further, the bioapplicable light irradiation device shown in FIG. 4 has additional configurations such as a metal layer 203, a metal sealing film 212, a fill material 210, a sealing adhesive 211, a light extraction improving film 216, and an adhesive layer 201. have. The metal layer 203 is interposed between the substrate 202 and the light emitting element 217. The metal sealing film 212, together with the filling material 210 and the sealing adhesive 211, is arranged so as to seal the entire light emitting element 217 with the substrate 202. The light extraction improving film 216 is arranged on the biological application surface of the substrate 202 so as to coincide with the light emitting portion 218, and the adhesive layer 201 is arranged around the light emitting portion 218.
Hereinafter, each member and each layer of the bioapplicable light irradiation device will be described.

[substrate]
The substrate of the bioapplied light irradiation device used in the present invention is preferably a flexible substrate.
Further, the substrate preferably has a water vapor transmittance of 1 × ^10-2 g / m ² / day or less.

In the present invention, it is preferable that the substrate contains a thermoplastic resin as a main component. Here, the "main component" in the substrate of the biologically applicable light irradiation device means a component that occupies 50% by mass or more of the total mass of the substrate. The substrate preferably contains 80% by mass or more of the thermoplastic resin, and more preferably 90% by mass or more. Further, the substrate may be a single layer or a laminated body having two or more layers. The substrate is preferably a single layer. It is preferable that the substrate does not have a layer not containing a thermoplastic resin as a main component, such as a layer containing an inorganic film as a main component, in order to be usable in a disposable device and to be inexpensive. Therefore, it is preferable to use a flexible substrate on which a barrier layer or the like is not formed.
There are no restrictions on the thermoplastic resin that is the main component of the substrate. Examples of the thermoplastic resin used as the main component of the substrate include polyester and the like.
In the present invention, the substrate is preferably a polyester film, more preferably a polyethylene terephthalate (PET) film or a polyethylene naphthalate (PEN) film, and particularly preferably a PEN film. Water vapor transmission rate is about 21g / m ² / day, about at PEN film 6.7g / m ² / day with a PET film. In addition, the plastic materials described in "Transparent Conductive Film" supervised by CMC Publishing and Saburo Tabata, and "New Development IV of Transparent Conductive Conductor" supervised by CMC Publishing and Yutaka Sawada, are described in Japanese Patent Publication No. 2014-515360. A plastic material can also be preferably used as a substrate material.
In the present invention, it is preferable to adopt a flexible substrate having a ^{water vapor transmittance of 1 × 10 −2} g / m ² / day or less by forming an inorganic layer (for example, SiO, SiN, SiON) on these films. .. The thickness of the inorganic layer is preferably 200 nm from the viewpoint of preventing cracks. Also, it is not always necessary to form an organic layer.
The present invention does not exclude that the substrate contains a curable resin component. When a curable resin is used for the substrate, it is preferable to control the curing and the content in the substrate to the extent that the flexibility is not completely lost.

It is preferable to reduce the thickness of the substrate from the viewpoint of suppressing the peeling of the bioapplied light irradiation device from the living body when the bioapplied light irradiation device is applied to the living body. In the present invention, the thickness of the substrate is preferably 20 to 200 μm, more preferably 20 μm to 125 μm, and particularly preferably 20 μm to 80 μm. When the thickness of the film substrate is reduced, the rigidity of the film can be reduced, and as a result, the ability to follow a living body having many curved surfaces (for example, the skin of the living body) is improved, and the film is less likely to be peeled off during use.
Here, the thickness of the substrate and each layer described later in the present specification is a thickness measured by the method specified in JIS7130 (many products are sold in contact type and non-contact type).

[Light emitting element]
The light emitting device preferably includes an organic semiconductor or quantum dots. The form of the light emitting element is not particularly limited, but it is preferable that the outer shape is layered. In the following description, a light emitting element having a layered outer shape may be referred to as a “light emitting body layer”.
There are no restrictions on the light emitting element. Examples of light emitting devices including organic semiconductors include organic electroluminescence devices (organic light emitting diodes: also referred to as OLEDs), polymer light emitting diodes (PLEDs), organic light emitting electrochemical cells (OLEC), and the like. Further, as an example of a light emitting device containing quantum dots, an electroluminescence device containing quantum dots in a light emitting layer and the like can be mentioned.
The bioapplied light irradiation device used in the present invention preferably has an organic electroluminescence (EL) element as its light emitting element, and more preferably a layered organic EL element. In the following description, the layered organic EL element and the layered EL element containing quantum dots in the light emitting layer are collectively referred to as an "EL type light emitting body layer".
The EL-type illuminant layer emits light when carriers (holes and electrons) are injected into the luminescent material from the anode and cathode, and the excited luminescent material generated by the recombination energy of the carriers is radiated and deactivated. .. This EL-type illuminant layer has at least an anode, a cathode, and a light emitting layer provided between the anode and the cathode. Of these, the anode may be arranged so as to be on the substrate side, or the cathode may be arranged so as to be on the substrate side, but it is preferable that the anode is arranged so as to be on the substrate side. Further, only a light emitting layer may be provided between the anode and the cathode, or one or more organic layers may be provided in addition to the light emitting layer. Examples of such other organic layers include a hole transport layer, a hole injection layer, an electron blocking layer, a hole blocking layer, an electron injection layer, an electron transport layer, an exciton blocking layer, and the like. The hole transport layer may be a hole injection transport layer having a hole injection function, and the electron transport layer may be an electron injection transport layer having an electron injection function. A specific structural example of the EL-type illuminant layer is shown in FIG.
In FIG. 4, 204 represents an anode, 205 represents a hole injection layer, 206 represents an interlayer (which may be a hole transport layer), 207 represents a light emitting layer, 208 represents an electron injection layer, and 209 represents a cathode. If desired, an electron transport layer or a hole blocking layer may be provided between the light emitting layer 207 and the electron injection layer 208.
Hereinafter, each member of the EL type illuminant layer and each layer will be described.

(anode)
As the anode in the luminescent material layer, a metal having a large work function (4 eV or more), an alloy, an electrically conductive compound, or a mixture thereof as an electrode material is preferably used. Specific examples of such electrode materials include metals such as Au and conductive transparent materials such as _{CuI, indium tin oxide (ITO), SnO 2, and ZnO.} Further, a material such as IDIXO (In ₂ O _3- ZnO) which is amorphous and can produce a transparent conductive film may be used. For the anode, a thin film may be formed by forming a thin film of these electrode materials by a method such as thin film deposition or sputtering, and a pattern having a desired shape may be formed by a photolithography method, or when pattern accuracy is not required so much (about 100 μm or more). ), A pattern may be formed through a mask having a desired shape during vapor deposition or sputtering of the electrode material. Alternatively, when a coatable material such as an organic conductive compound is used, a wet film forming method such as a printing method or a coating method can also be used. When emitting light from this anode, it is desirable to increase the transmittance to more than 10%, and the sheet resistance as the anode is preferably 100 Ω □ or less, more preferably 20 Ω □ or less, and particularly preferably 5 Ω □ or less. Further, the film thickness depends on the material, but is usually selected in the range of 10 to 1000 nm, preferably 10 to 200 nm.
Here, in particular, when a plastic sheet is used as the substrate and the light emitting body layer is arranged so that the anode thereof is on the substrate side (plastic sheet side), the anode should be designed in consideration of the following. Is preferable.
Generally, when a transparent conductive film such as an indium tin oxide film is formed on the surface of a plastic sheet by a vapor deposition method such as a vapor deposition or a sputtering method, the plastic sheet has lower heat resistance than a glass substrate, and therefore is usually a substrate. Film formation is performed at a relatively low temperature. Therefore, the film-formed transparent conductive film tends to have low crystallinity and high electrical resistance. Therefore, in the present invention, the transparent conductive film provided on the surface of the plastic sheet is formed thicker than the case where the film is formed on the surface of the glass substrate, or a conductive transparent material and a material having higher conductivity (highly conductive material). ) Are combined to form an anode. As a method of combining a transparent conductive material and a highly conductive material, for example, after forming a silver or copper metal (highly conductive material) in a mesh shape on the surface of a plastic sheet, indium tin oxide or the like is used to cover the mesh. Examples thereof include a method of forming an anode by forming a conductive transparent material in the above, and a method of applying a conductive polymer such as PEDT: PSS to a metal formed in a mesh shape to form an anode. Here, the pitch and line width of the mesh formed of metal can be appropriately selected according to the appropriate electrical resistance determined by the target brightness and the dimensions of the bioapplied light irradiation device, and usually the pitch is 100 to 100 to. It is appropriate that the line width is about 500 μm and the line width is 1 to 20 μm.
Although a method of forming a conductive material in a mesh shape to reduce the resistance of the electrode is effective, it is desirable to further adopt a method of filling and flattening the unevenness on the surface of the anode. For this purpose, for example, a method of providing a coating type hole injection layer or providing a thick highly conductive organic material to reduce unevenness can be used.
It is preferable and most effective to set the sheet resistance of the anode to 10 Ω □ or less, preferably 5 Ω or less, particularly preferably 3 Ω □ or less without using a mesh electrode, in order to avoid voltage drop due to the resistance of the anode. As such an electrode, it is desirable to use a transmissive metal thin film for the anode. Generally, metal does not transmit light, but light can be transmitted by forming an ultrathin film of 20 nm or less. The optimum thickness can be found by the relationship between the sheet resistance and the transmittance, but it is generally preferable that the thickness is 10 nm or less. Ag, Al, Cu, and Au can be used as the metal thin film referred to here, but it is preferable to use Ag in terms of stability and ease of process.
When these metals are used for the anode, there arises a problem that the hole injection property is lowered if the work functions of the hole injection layer and the hole transport layer used as adjacent organic materials are significantly deviated. The reason is that the work function of Ag is about 4.3 eV, Al is about 4.2 eV, and Cu is about 4.6 eV, which is different from the general hole injection material of 5.0 to 5.2 eV. This is because smooth hole injection is unlikely to occur. In consideration of this point, it is preferable to laminate a highly conductive oxide conductor such as ITO or IZO on the upper surface of the metal thin film.
Further, when an inorganic conductive film such as indium tin oxide is formed on the surface of a plastic sheet, it is preferable to provide an adhesive layer on the surface of the plastic sheet for improving adhesion and to form the conductive film on the adhesive layer. Examples of the adhesive layer include, but are not limited to, metal oxides such as SiOx, SiN, SiON, and Al ₂ O _3.
Commercially available electrode substrates with a transparent conductive film formed on a plastic sheet include Freclear (manufactured by TDK), PECF series (manufactured by Pexel Technologies), and indium tin oxide coated PET (manufactured by Sigma Aldrich, 639303-1EA, 5EA). Etc.), a carbon nanotube-coated film, a film coated with nano-silver (manufactured by Toray Industries, Inc., etc.), a silver nano-rod having graphene as a conductive film, and the like, and these may be used as a laminated structure of a plastic sheet and an anode.

(cathode)
On the other hand, as the cathode, a metal having a small work function (4 eV or less) (referred to as an electron-injectable metal), an alloy, an electrically conductive compound, or a mixture thereof is used as an electrode material. Specific examples of such electrode materials include sodium, sodium-potassium alloy, magnesium, lithium, magnesium / copper mixture, magnesium / silver mixture, magnesium / aluminum mixture, magnesium / indium mixture, aluminum / aluminum oxide (Al ₂ O). ₃ ) Examples include mixtures, indium, lithium / aluminum mixtures, rare earth metals and the like. Among these, from the viewpoint of electron injectability and durability against oxidation and the like, a mixture of an electron injectable metal and a second metal which is a stable metal having a larger work function value than this, for example, a magnesium / silver mixture. Magnesium / aluminum mixture, magnesium / indium mixture, aluminum / aluminum oxide (Al ₂ O ₃ ) mixture, lithium / aluminum mixture, aluminum and the like are suitable. The cathode can be produced by forming a thin film of these electrode materials by a method such as vapor deposition or sputtering. The sheet resistance of the cathode is preferably several hundred Ω / □ or less, and the film thickness is usually selected in the range of 10 nm to 5 μm, preferably 50 to 200 nm. Since the emitted light is transmitted, it is convenient that the emission brightness is improved if either the anode or the cathode of the light emitting body layer is transparent or translucent.
Further, by using the conductive transparent material mentioned in the description of the anode for the cathode, a transparent or translucent cathode can be produced, and by applying this, a light emitting body in which both the anode and the cathode have transparency. Layers can be made.

(Light emitting layer)
The light emitting layer is a layer that emits light after excitons are generated by recombination of holes and electrons injected from the anode and the cathode, respectively, and the light emitting material may be used alone for the light emitting layer. , Preferably includes a light emitting material and a host material. In the present invention, it is preferable to use an organic semiconductor or quantum dots as a light emitting material. These preferable ranges and specific examples will be described later. In order for the bioapplied light irradiation device of the present invention to exhibit high luminous efficiency, it is important to confine the singlet excitons and triplet excitons generated in the light emitting material in the light emitting material. Therefore, it is preferable to use a host material in addition to the light emitting material in the light emitting layer. As the host material, an organic compound in which at least one of the excitation singlet energy and the excitation triplet energy has a value higher than that of the light emitting material can be used. As a result, the singlet excitons and triplet excitons generated in the luminescent material can be confined in the molecules of the luminescent material, and the luminous efficiency can be sufficiently brought out. However, even if the singlet excitons and triplet excitons cannot be sufficiently confined, it may be possible to obtain high luminous efficiency, so any host material that can achieve high luminous efficiency is particularly restricted. Can be used in the present invention. In the EL-type light emitting body layer of the present invention, light emission is generated from a light emitting material contained in the light emitting layer. This light emission may be any of fluorescent light emission, delayed fluorescent light emission, and phosphorescent light emission, and two or more kinds of light emission may be generated. Further, the light emitted from the host material may be partially or partially emitted.
When a host material is used, the amount of the compound of the present invention, which is a light emitting material, contained in the light emitting layer is preferably 0.1% by weight or more, more preferably 1% by weight or more, and 50. It is preferably 0% by weight or less, more preferably 20% by weight or less, and further preferably 10% by weight or less.
The host material in the light emitting layer is preferably an organic compound having a hole transporting ability and an electron transporting ability, preventing the emission from having a long wavelength, and having a high glass transition temperature.
Hereinafter, specific examples of organic semiconductors that can be used as light emitting materials will be illustrated. However, the organic semiconductor used as a light emitting material in the present invention should not be construed as being limited by these specific examples. In addition, the light emitting material described in Non-Patent Document 1 can also be used.
(Non-Patent Document 1) Organic Light-emitting Materials ans Devices, Edited by Heng Meng, Tayer & Francis, New York.

Examples of the polymer light emitting material include those having polyphenylvinylene (PPV) and polyfluorene (PF) as basic skeletons. By changing the structure of the copolymer of the polymer light emitting material, various light emitting colors such as blue, green, and red can be realized. Further, when a phosphorescent type dopant whose ligand is improved to a dendrimer type is mixed with the polymer of these basic skeletons, energy transfer occurs and a phosphorescent type polymer light emitting material can be obtained. A typical material of the basic skeleton is shown below, and a known polymer-type organic EL material including a copolymer with a triphenylamine derivative can be used. Moreover, there is no limitation on these molecular weights and the like.
Since these polymer-type organic EL materials do not sublimate, they are dissolved in various organic solvents, and then a thin film is formed by using various known processes such as a spin coating method, an inkjet method, a gravure printing method, and a screen printing method. It is possible to do.

Next, quantum dots that can be used as a light emitting material will be described.
The quantum dots are semiconductor nanometer-sized fine particles (semiconductor nanocrystals), and are not particularly limited as long as they are light-emitting materials that produce a quantum confinement effect (quantum size effect). Specifically, II such as MgS, MgSe, MgTe, CaS, CaSe, CaTe, SrS, SrSe, SrTe, BaS, BaSe, BaTe, ZnS, ZnSe, ZnTe, CdS, CdSe, CdTe, HgS, HgSe and HgTe. -VI group semiconductor compounds, IIIV semiconductor compounds such as AlN, AlP, AlAs, AlSb, GaAs, GaP, GaN, GaSb, InN, InAs, InP, InSb, TiN, TiP, TiAs and TiSb, Si, Ge and Pb. In addition to semiconductor crystals containing group IV semiconductors such as InGaP, semiconductor compounds containing three or more elements such as InGaP can be mentioned. Alternatively, a semiconductor crystal obtained by doping the above semiconductor compound with ^{a cation of a rare earth metal such as Eu 3+} , Tb ³⁺ , Ag ⁺ , or Cu ⁺ or a cation of a transition metal can be used. Among them, semiconductor crystals such as CdS, CdSe, CdTe, and InGaP are preferable from the viewpoints of ease of fabrication, controllability of particle size capable of obtaining light emission in the visible range, and fluorescence quantum yield.

The quantum dot may be composed of one kind of semiconductor compound or two or more kinds of semiconductor compounds. For example, a core made of a semiconductor compound and a shell made of a semiconductor compound different from the core. It may have a core-shell type structure having and. As a core-shell type quantum dot, the emission efficiency of the quantum dot is increased by using a material having a bandgap higher than that of the semiconductor compound forming the core as the semiconductor compound constituting the shell so that excitons are confined in the core. Can be enhanced. Examples of the core-shell structure (core / shell) having such a bandgap magnitude relationship include CdSe / ZnS, CdSe / ZnSe, CdSe / CdS, CdTe / CdS, InP / ZnS, GaP / ZnS, Si / ZnS, and the like. InN / GaN, InP / CdSSe, InP / ZnSeTe, GaInP / ZnSe, GaInP / ZnS, Si / AlP, InP / ZnSTe, GaInP / ZnSTe, GaInP / ZnSse and the like can be mentioned.

The size of the quantum dots may be appropriately controlled by the material constituting the quantum dots so that light having a desired wavelength can be obtained. The energy band gap of quantum dots increases as the particle size decreases. That is, as the crystal size becomes smaller, the emission of the quantum dots shifts to the blue side, that is, to the high energy side. Therefore, by changing the size of the quantum dot, the emission wavelength can be adjusted over the wavelength region of the spectrum in the ultraviolet region, the visible region, and the infrared region. Generally, the particle size (diameter) of the quantum dots is preferably in the range of 0.5 to 20 nm, and particularly preferably in the range of 1 to 10 nm. The narrower the size distribution of the quantum dots, the clearer the emission color can be obtained.

Further, the shape of the quantum dot is not particularly limited, and may be spherical, rod-shaped, disk-shaped, or other shape. When the quantum dots are not spherical, the particle size of the quantum dots can be a value assuming that the quantum dots are true spheres having the same volume. Information such as the particle size, shape, and dispersion state of the quantum dots can be obtained by a transmission electron microscope (TEM). Further, the crystal structure and particle size of the quantum dots can be known by X-ray crystal diffraction (XRD). Furthermore, information on the particle size and surface of the quantum dots can be obtained from the UV-Vis absorption spectrum.

The luminescent material can be selected according to the condition of the biological disease to which it is applied. For example, blue light having a size of about 400 to 500 nm may be effective for skin diseases such as skin cancer and acne. Therefore, when the bioapplying light irradiation device used in the present invention is used for the treatment of such skin diseases, it is preferable to use a light emitting material having a maximum light emission at 400 to 500 nm. When a photochemotherapeutic agent is used in combination, it is preferable to use a luminescent material having a maximum luminescence at 500 to 700 nm, which is the absorption of the porphyrin derivative produced in the body. In addition, in the living body, light in the wavelength range in which hemoglobin and water have a large absorption is difficult to penetrate into the body. Therefore, in order to irradiate light from outside the body and penetrate deeper into the body, it is preferable to use a light emitting material having a maximum emission in a long wavelength region of 600 nm or more, and to avoid absorption by water existing in the living tissue, 1200 nm. It is preferable to use a light emitting material having a light emitting maximum in the range up to the degree.

(Injection layer)
The injection layer is a layer provided between the electrode and the organic layer in order to reduce the driving voltage and improve the emission brightness. There are a hole injection layer and an electron injection layer, and between the anode and the light emitting layer or the hole transport layer, And may be present between the cathode and the light emitting layer or the electron transporting layer. The injection layer can be provided as needed.

(Blocking layer)
The blocking layer is a layer capable of blocking the diffusion of charges (electrons or holes) and / or excitons existing in the light emitting layer to the outside of the light emitting layer. The electron blocking layer can be arranged between the light emitting layer and the hole transporting layer to prevent electrons from passing through the light emitting layer toward the hole transporting layer. Similarly, the hole blocking layer can be placed between the light emitting layer and the electron transporting layer to prevent holes from passing through the light emitting layer towards the electron transporting layer. The blocking layer can also be used to prevent excitons from diffusing outside the light emitting layer. That is, the electron blocking layer and the hole blocking layer can also function as exciton blocking layers, respectively. The electron blocking layer or exciton blocking layer referred to in the present specification is used in the sense that one layer includes a layer having the functions of an electron blocking layer and an exciton blocking layer.

(Hole blocking layer)
The hole blocking layer has a function of an electron transporting layer in a broad sense. The hole blocking layer has a role of blocking the holes from reaching the electron transporting layer while transporting electrons, which can improve the recombination probability of electrons and holes in the light emitting layer. As the material of the hole blocking layer, a material of the electron transport layer described later can be used as needed.

(Electronic blocking layer)
The electron blocking layer has a function of transporting holes in a broad sense. The electron blocking layer has a role of blocking electrons from reaching the hole transporting layer while transporting holes, which can improve the probability of recombination of electrons and holes in the light emitting layer. ..

(Exciton blocking layer)
The exciton blocking layer is a layer for preventing excitons generated by recombination of holes and electrons in the light emitting layer from diffusing into the charge transport layer, and the excitons are inserted by inserting this layer. It is possible to efficiently confine it in the light emitting layer, and it is possible to improve the light emitting efficiency of the element. The exciton blocking layer can be inserted into either the anode side or the cathode side adjacent to the light emitting layer, and both can be inserted at the same time. That is, when the exciton blocking layer is provided on the anode side, the layer can be inserted between the hole transport layer and the light emitting layer adjacent to the light emitting layer, and when inserted on the cathode side, the light emitting layer and the cathode can be inserted. The layer can be inserted adjacent to the light emitting layer between and. Further, a hole injection layer, an electron blocking layer, or the like can be provided between the anode and the exciton blocking layer adjacent to the anode side of the light emitting layer, and the cathode and the excitation adjacent to the cathode side of the light emitting layer can be provided. An electron injection layer, an electron transport layer, a hole blocking layer, and the like can be provided between the child blocking layer and the electron blocking layer. When the blocking layer is arranged, it is preferable that at least one of the excited singlet energy and the excited triplet energy of the material used as the blocking layer is higher than the excited singlet energy and the excited triplet energy of the light emitting material.

(Hole transport layer)
The hole transport layer is made of a hole transport material having a function of transporting holes, and the hole transport layer may be provided with a single layer or a plurality of layers.
The hole transporting material has either injection or transport of holes or an electron barrier property, and may be either an organic substance or an inorganic substance. Known hole transporting materials that can be used include, for example, triazole derivatives, oxadiazole derivatives, imidazole derivatives, carbazole derivatives, indolocarbazole derivatives, polyarylalkane derivatives, pyrazoline derivatives and pyrazolone derivatives, phenylenediamine derivatives, arylamine derivatives, etc. Examples thereof include amino-substituted chalcone derivatives, oxazole derivatives, styrylanthracene derivatives, fluorenone derivatives, hydrazone derivatives, stilben derivatives, silazane derivatives, aniline copolymers, and conductive polymer oligomers, especially thiophene oligomers, which include porphyrin compounds and aromatics. It is preferable to use a group tertiary amine compound and a styrylamine compound, and it is more preferable to use an aromatic tertiary amine compound.

(Electronic transport layer)
The electron transport layer is made of a material having a function of transporting electrons, and the electron transport layer may be provided with a single layer or a plurality of layers.
The electron transporting material (which may also serve as a hole blocking material) may have a function of transmitting electrons injected from the cathode to the light emitting layer. Examples of the electron transporting layer that can be used include nitro-substituted fluorene derivatives, diphenylquinone derivatives, thiopyrandioxide derivatives, carbodiimides, freolenidenemethane derivatives, anthracinodimethane and anthrone derivatives, and oxadiazole derivatives. Further, among the above oxadiazole derivatives, a thiadiazole derivative in which the oxygen atom of the oxadiazole ring is replaced with a sulfur atom, and a quinoxalin derivative having a quinoxalin ring known as an electron-withdrawing group can also be used as an electron transport material. Further, a polymer material in which these materials are introduced into a polymer chain or these materials are used as a polymer main chain can also be used.

(Interlayer)
The interlayer has at least one of a function of receiving holes from an anode, a function of transporting holes, a function of supplying holes to a light emitting layer, and a function of blocking electrons injected from a cathode. However, it usually refers to a layer that is arranged adjacent to the light emitting layer and has a function of separating the light emitting layer from the anode, or the light emitting layer from the hole injection layer or the hole transport layer. As the material of the interlayer, for example, a heat-crosslinked polymer material can be used.

Hereinafter, preferred materials that can be used for the EL-type illuminant layer will be specifically exemplified. However, the materials that can be used in the present invention are not limitedly interpreted by the following exemplary compounds. Further, even a compound exemplified as a material having a specific function can be diverted as a material having another function. _{In addition, R, R 1 to} R ₁₀ in the structural formula of the following exemplary compounds each independently represent a hydrogen atom or a substituent. n represents an integer of 3 to 5.

As a preferable compound that can be used as a host material for the light emitting layer, for example, the compounds described in paragraphs [0055] to [0059] of JP-A-2015-129240 can be mentioned. As a preferable compound that can be used as a hole injection material, for example, the compound described in paragraph [0061] of JP-A-2015-129240 can be mentioned. As a preferable compound that can be used as a hole transport material, for example, the compounds described in paragraphs [0063] to [0068] of JP-A-2015-129240 can be mentioned. As a preferable compound that can be used as an electron blocking material, for example, the compound described in paragraph [0070] of JP-A-2015-129240 can be mentioned. As a preferable compound that can be used as a hole blocking material, for example, the compound described in paragraph [0072] of JP-A-2015-129240 can be mentioned. As a preferable compound that can be used as an electron transport material, for example, the compounds described in paragraphs [0074] to [0076] of JP-A-2015-129240 can be mentioned. As a preferable compound that can be used as an electron injection material, for example, the compound described in paragraph [0078] of JP-A-2015-129240 can be mentioned. Further, a stabilizing material can be mentioned as a material that can be added. As a preferable compound that can be used as a stabilizing material, for example, the compound described in paragraph [0080] of JP-A-2015-129240 can be mentioned. The description of each paragraph of Japanese Patent Application Laid-Open No. 2015-129240 cited in this paragraph is referred to herein as a part of the present specification.

The film forming method of each layer constituting the EL type illuminant layer is not particularly limited, and may be produced by either a dry process or a wet process.

[LEC type illuminant layer]
Next, the LEC type illuminant layer will be described.
The LEC type light emitting body layer is a device having a simple structure in which the light emitting layer sandwiches a mixture of a light emitting organic semiconductor material and an electrolyte with electrodes. When a voltage is applied to the device, ions move at the interface between the electrode and the organic material layer, a pin bond is automatically formed at the interface between the cathode and the anode, the carrier balance is automatically optimized, and the device operates at a low voltage. It has characteristics. A specific structural example of the LEC type illuminant layer is shown in FIG. In FIG. 5, 121 represents an anode, 122 represents a light emitting layer, and 123 represents a cathode.
For a description of the anode and cathode configurations, the corresponding description of the EL-type illuminant layer above can be referred to, but the efficiency of electron and hole injection can be selected independently of the work function of the electrodes.
The light emitting layer of the LEC type light emitting body layer contains a polymer semiconductor material and an electrolyte (Non-Patent Document 2). The polymer semiconductor material can emit phosphorescence or the like by using a so-called doping material, and includes an organic semiconductor or quantum dots. For the description and preferred range of the quantum dots, the description and preferred range of the quantum dots used in the EL-type illuminant layer can be referred to.
(Non-Patent Document 2 Nature Communications, DOI: 10.1038 / ncomm2002)

Currently, organic semiconductors that can be used as luminescent materials are limited to polymer-type fluorescent materials, but in principle, it is possible to dope a phosphorescent luminescent material and use a low-molecular-weight fluorescent or phosphorescent material. be. Further, as the ionic liquid, those known in patent documents and non-patent documents are widely used.

The thickness of the illuminant layer varies depending on whether it is an EL type or a LEC type, but it is preferably 2 μm or less, more preferably 1000 nm or less in order to reduce the driving voltage of the bioapplied light irradiation device. It is preferably 500 nm or less, and more preferably 500 nm or less. Further, the thickness of the EL-type illuminant layer is preferably 10 to 500 nm, more preferably 10 to 200 nm, and 20 It is more preferably ~ 150 nm. The thickness of the LEC type illuminant layer is preferably 200 nm to 2 μm.

[Metal layer]
In the bioapplied light irradiation device used in the present invention, the light emitting element has a light emitting layer sandwiched between electrodes, and a metal is further formed between the electrode (the electrode on the substrate side) located between the substrate and the light emitting layer and the substrate. It is preferable to have a layer. This is due to the following reasons.
That is, the biologically applicable light irradiation device using a flexible substrate such as a PEN substrate is preferably configured to suppress deterioration even when the light emission time is several hours. This is because when a flexible substrate such as a PEN substrate is used, it is conceivable that water originally contained in the substrate during manufacturing may diffuse to the organic EL element and cause deterioration of the organic EL element. By further having a metal layer between the electrode located between the substrate and the light emitting layer and the substrate, the metal layer functions as a waterproof layer for preventing moisture from entering the light emitting layer, and deterioration of such an organic EL element. Can be suppressed.
In addition, when a biologically applicable light irradiation device is attached to the skin of a living body to emit light, the skin of the living body sweats. Therefore, when a flexible substrate is used (especially when a thin flexible substrate of 125 μm or less is used or a PEN substrate having no barrier layer is used), between the electrode located between the substrate and the light emitting layer and the substrate. This is because the structure having a metal layer effectively shields both the water originally contained in the substrate and the water derived from sweat, and the adverse effect of the water on the organic semiconductor layer, the quantum dot layer and the cathode can be minimized. preferable.
As the metal layer laminated on the substrate (the metal layer arranged between the electrode on the substrate side and the substrate), a silver or aluminum film is preferably used. In order to increase the adhesion of the metal layer to the substrate, it is possible to use another type of metal such as chromium as the base. Further, in order to prevent the oxidation of silver or aluminum, an alloy in which silver or aluminum is combined with another metal can also be used.
The metal layer is preferably a metal thin film, and more preferably has a thickness of 3 nm to 20 nm.

[Metal sealing film]
The metal sealing film is provided as needed. The metal sealing film protects the light emitting element and also functions as a heat sink that dissipates heat generated by the light emitting element to the outside. In the bioapplied light irradiation device shown in FIG. 4, the upper surface and the side surface of the light emitting element 217 are covered with a fill material 210, a metal sealing film 212 is provided so as to cover the fill material 210, and the metal seal is further provided. The lower end of the waterproof film 212 and the surface of the substrate 202 are sealed with a sealing adhesive 211.
As shown in FIG. 4, for example, the biologically applicable light irradiation device used in the present invention has a light emitting element 217 only on one surface side of the substrate 202, and the surface of the light emitting element 217 opposite to the substrate 202 and the light emitting element. It is preferable that the side surface of the 217 is sealed with the metal sealing film 211 from the viewpoint of avoiding low-temperature burns of the living body to which the living body-applied light irradiation device is applied. On the other hand, in the present invention, it is preferable that the side surface of the substrate is not sealed with a metal sealing film from the viewpoint of inexpensively manufacturing a bioapplicable light irradiation device.

The metal film used for the metal sealing film is not limited to the metal film made of a single metal, and may contain a component other than the metal as long as it can efficiently radiate heat. Further, instead of the metal film, a material capable of efficiently radiating heat may be used instead.
The sealing adhesive that seals between the metal sealing film and the substrate is not particularly limited, but it is preferable to select and use an adhesive having a large water and oxygen blocking property. Commercially available products of such adhesives include, for example, UV (Ultraviolet) curable epoxy resin (TB3124M manufactured by ThreeBond Co., Ltd.) and OleDry-F (Oledry-F) manufactured by Futaba Corporation. Product name), Moisture cut (product name) manufactured by Moresco, etc. can be mentioned. Further, a sealing film mixed with a moisture-proofing agent manufactured by Ajinomoto Fine-Techno Co., Ltd. can also be preferably used.

[Adhesive layer]
The bioapplicable light irradiation device used in the present invention preferably has an adhesive layer provided on at least a part of the bioapplyable surface of the substrate, if necessary. Here, the pressure-sensitive adhesive layer is a layer formed by applying a pressure-sensitive adhesive material to a biologically applicable surface of a substrate. In the following description, the region of the bioapplyable surface on which the adhesive layer is provided may be referred to as a “adhesive region”. By providing the adhesive layer on the bioapplyable surface of the substrate, the bioapplicable light irradiation device can be easily attached to and fixed to the living body.
In the present invention, it is preferable that the bioapplied light irradiation device can be fixed to the skin of a living body via an adhesive layer. Here, when the light emitted from the light emitting portion of the bioapplied light irradiation device is directly irradiated to the affected portion, it is preferable that the emitted light is irradiated to the affected portion without exception. Therefore, it is preferable that the adhesive layer is provided only around the light emitting portion on the biologically applicable surface of the substrate of the biologically applicable light irradiation device. When the pressure-sensitive adhesive layer is provided around the light emitting portion of the bioapplyable surface, the width of the pressure-sensitive adhesive region is preferably 1 to 10 mm, more preferably 1 to 5 mm, and preferably 1 to 3 mm. When forming such an adhesive region using a commercially available adhesive tape, it is preferable to cut out the central portion of the adhesive tape so that the adhesive tape does not cover the light emitting portion. As the adhesive tape, in addition to the usual commercially available adhesive tape, an adhesive tape using a silicone type adhesive can be used. Since the adhesive tape using the silicone type adhesive is easy to reattach, it is particularly preferably used for the bioapplied light irradiation device of the present invention.

[Light extraction improvement film]
The biologically applicable light irradiation device used in the present invention may have a light extraction improving film on the biologically applicable surface of the substrate 202, if necessary. Thereby, the light irradiation efficiency to the living body can be increased. The light extraction improving film may be arranged at least on the light emitting portion of the biological application surface, and is preferably arranged in a region corresponding to the light emitting portion.

[Photochemotherapy agent layer]
In the bioapplying light irradiation device used in the present invention, it is preferable to provide a photochemotherapeutic agent layer on the bioapplying surface of the substrate 202, if necessary. The photochemotherapeutic agent layer is a layer composed of a chemotherapeutic agent, and can be provided, for example, by applying a photochemotherapeutic agent to a bioapplyable surface. As a result, the patient can eliminate the act of applying the photochemotherapy agent to the affected area by himself / herself before use. The photochemotherapeutic agent layer may be arranged at least in the light emitting portion of the bioapplying surface, and is preferably arranged in a region corresponding to the light emitting portion. The photochemotherapeutic agent is not particularly limited, and examples thereof include those containing 5-aminolevulinic acid (also referred to as 5-ALA) as an active ingredient. It has been studied that 5-aminolevulinic acid accumulates in cancer cells and is metabolized to protoporphyrin IX, which acts as a photosensitizer. In addition to 5-aminolevulinic acid, various known photosensitizers can be used. Specifically, AP Castane et al., Photodiagnosis Photodyn Ther., 2004, vol.1 p279; R. Bonnell, Chem. Soc. Rev., 1995, v. 24, p19; JCKennedy et al., Photochemistry and Photobiology B: Biology, 1992, It is described in v.14, p275. However, the photochemotherapeutic agents that can be used in the present invention are not limited to these.

[Protective film]
When the above-mentioned adhesive layer or photochemotherapy agent layer is provided on the bioapplyable surface of the bioapplyable light irradiation device, a protective film may be laminated on the adhesive material layer or the photochemotherapy agent layer, if necessary. preferable. In this case, the user may perform treatment by peeling off the protective film to expose the surface of the adhesive layer or the photochemotherapy agent layer and attaching the surface to the affected area before using the bioapplied light irradiation device. can. That is, the treatment by photodynamic therapy can be easily started without separately applying the cream of the photochemotherapy agent to the affected area.

[Connection structure with power cable]
In the bioapplied light irradiation device shown in FIG. 4, a wiring extraction pad 213 is connected to the anode 204 via a metal layer 203, and a power cable 50a is connected to the wiring extraction pad 213 via a conductive adhesive 214. It is connected. In the biologically applicable light irradiation device of FIG. 4, the wiring extraction pad 213 is connected only to the anode 204, but it is also preferable to connect the wiring extraction pad to both the anode 204 and the cathode 209.

[Biological body to which the biologically applicable light irradiation device is applied, application method]
Examples of the living body to which the living body-applied light irradiation device used in the present invention is applied include animals as well as humans. Examples of animals include mammals.
In addition, the light emitted from the bioapplied light irradiation device may irradiate any part of the living body. For example, it can irradiate the legs, shoulders, arms, hands, head, face, abdomen, back and the like. Irradiation can be applied not only to the skin but also to diseases such as brain tumors. In the present invention, it is preferable that the light emitted from the bioapplied light irradiation device irradiates the skin of the living body. Further, it is more preferable that the light emitted from the bioapplied light irradiation device irradiates the skin of a specific affected part of the living body or the skin in the vicinity of the affected part.
The bioapplied light irradiation device usually has a light emitting unit 218. It is preferable that the adhesive material 201 for attaching to the living body is formed around the light emitting portion 218 in the biological application light irradiation device, but the adhesive material 201 is not provided and the adhesive material 201 is formed from the upper part of the biological application light irradiation device. The device may be attached to the living body by covering the periphery or the whole with an adhesive material such as surgical tape.

The biologically applicable light irradiation device may be attached to any part of the living body. It can be worn on the legs, shoulders, arms, hands, head, face, abdomen, back, etc.
The biologically applicable light irradiation device can be shaped according to the mounting site of the living body. For example, the biologically applicable light irradiation device may have a shape that goes around the arm once or a shape that goes around the wrist like a wristwatch. Further, the biologically applicable light irradiation device may be a flexible film that covers a large area such as a compress. The biologically applicable light irradiation device preferably has an elongated linear shape when it is attached to a linear scar or wrinkle. Further, when the biologically applicable light irradiation device is applied to an organ such as the heart or lungs, the shape may be adjusted to match the shape of the organ. In addition, there are circular, elliptical, square, rectangular, etc. bio-applicable light irradiation devices, but they can be processed into any shape according to the shape of the affected area without being limited to these.
Further, when the biologically applicable light irradiation device used in the present invention is flexible, the user can bend it according to the shape of an arbitrary living body.

In the present invention, the irradiation intensity of the light emitting element ^{is preferably 3} to 80 mW / cm 2, but the applied voltage is applied at the start of the treatment or during the treatment depending on the treatment time and the degree of pain of the patient felt at the time of light irradiation. The irradiation intensity can be changed by changing.
The temperature at the time of light emission of the bioapplied light irradiation device is preferably less than 45 ° C. from the viewpoint of avoiding low-temperature burns, more preferably less than 44 ° C., and particularly preferably less than 42 ° C.

[Use of biologically applicable light irradiation device]
The biologically applicable light irradiation device used in the present invention can be effectively used for the treatment and beauty of a living body. By using the bioapplied light irradiation device, it is possible to obtain a thin, lightweight, and inexpensive treatment means capable of easily treating a skin disease or the like at home.
Examples of treatable diseases include skin diseases and internal diseases. For example, premalignant stage diseases, malignant diseases, and inflammatory skin diseases can be mentioned. Examples of pre-malignant skin disorders include Bowen's disease, actinic keratosis, arsenic keratosis, Paget's disease, and radiodermatitis. Malignant diseases include all types of basal cell carcinoma, squamous cell carcinoma, secondary metastases, and cutaneous T cell lymphoma. Inflammatory skin disorders include all types of dermatitis and psoriasis. Other examples of treatable diseases include primary and metastatic tumors, as well as inflammatory diseases such as connective tissue diseases, arthritis of all kinds, and inflammatory intestinal diseases. In addition, the diseases described in Japanese Patent Publication No. 2013-513555 can also be mentioned. The mechanisms by which phototherapy can treat these diseases are known (see, for example, CANCER June 15, 1997 / Volume 79 / Number 12, p2282). These diseases can be treated with the light emitted from the bioapplied light irradiation device used in the present invention.
In photodynamic therapy (PDT), a photosensitive therapeutic agent known as a photopharmaceutical is given to an area of the body to be treated for external or internal use, and the area is exposed to light of appropriate frequency and intensity. To activate the photochemotherapeutic agent. A variety of photochemotherapeutic agents are now available (see, eg, Japanese Patent No. 4651281 [0002]).
Other uses include cancer (eg skin cancer), acne, wrinkles, wound healing, anti-aging, and post-skin laser therapy (eg cosmetics), therapeutic and cosmetic purposes such as insomnia and depression. Can be mentioned.
In addition, the bioapplying light irradiation device used in the present invention is used alone for medical or cosmetic purposes, and is a light irradiation unit that irradiates a treatment or cosmetic treatment target with light in a skin disease treatment device or a beauty treatment device. Can also be used effectively.
As skin diseases for which the skin disease treatment device equipped with this bioapplicable light irradiation device is particularly effective, actinic keratosis, Bowen's disease, superficial basal cell carcinoma, confirmation of excised cancer cells, etc. in addition to skin diseases, acne Improvement, improvement of insomnia, improvement of depression, improvement of juxou, early recovery of trauma, prevention of infection by yellow staphylococcus, etc. can be mentioned because resistant bacteria are not generated when light is used.
In addition, a cosmetological treatment device having this bioapplicable light irradiation device can be effectively used especially for skin cosmetology. Examples of the purpose of beauty in which the bioapplying light irradiation device of the present invention is particularly effective include alleviation of spots and wrinkles, improvement of skin elasticity, removal of moles, and the like.

10 Biologically applicable light irradiation device with ID transmitter 20 Controller 21 Second communication unit 22 Input operation unit 23 Input unit 24 Clock function unit 25 Controller control unit (control unit)
26 Second storage unit (memory unit)
27 Display section 27
28 Drive circuit (power supply)
29 On / off switching unit 30 Device connection detection unit 40 ID transmission unit 41 First control unit 42 First storage unit 43 First communication unit 44 Power generation unit 50a, 50b Power cable (conductor)
60a, 60a, 60c Communication cable 70 Biologically applicable light irradiation device 80 RFID tag (ID transmitter)
90 RFID reader section (communication section)
91 Antenna 92 Communication unit 93 Control unit 94 Interface unit 102 Intermediate connector 104 Power cable 201 Adhesive layer 202 Board 203 Metal layer 204 Anode 205 Hole injection layer 206 Interlayer 207 Light emitting layer 208 Electron injection layer 209 Cathode 210 Fill material 211 Sealing Adhesive for 212 Metal film 213 Pad for taking out wiring 214 Conductive adhesive 216 Light extraction improvement film 217 Light emitting element 218 Light emitting part

Claims (6)

A living body having a light emitting element on one surface of a substrate having a water vapor transmittance of 1 × 10 ^-2 g / m ² / day or less and having a unique ID set as a biological application surface in which the other surface is in direct contact with the affected area. A biologically applicable light with an ID transmitting unit having an applicable light irradiation device and an ID transmitting unit attached to the biologically applicable light irradiation device and transmitting ID information corresponding to the ID set in the biologically applicable light irradiation device. With the irradiation device
A controller for controlling the drive of the biologically applicable light irradiation device is provided.
The controller
A communication unit that receives ID information transmitted from the ID transmission unit, and
A storage unit that stores usage history information including the number of times or time of use of one or more bioapplicable light irradiation devices for each device corresponding to a unique ID set for each bioapplicable light irradiation device.
A power source that supplies power to the bioapplied light irradiation device to which the unique ID is set (power is supplied when the power is on, and power is not supplied when the power is off).
The ID information received by the communication unit is read out, the usage history information stored corresponding to the same ID as the ID information is searched from the usage history information stored in the storage unit, and the usage history information is searched for. and it has a control unit for controlling so as not to the power on state if it is exceeded the allowable range of the number of uses or usage time based on the search result,
A bioapplyable light irradiation device in which a photochemotherapy agent layer is formed on a light emitting portion of the bioapplied surface (the light emitting portion referred to here represents a region obtained by projecting the light emitting layer onto the substrate). The bioapplying light irradiation device according to claim 1, wherein an adhesive layer is provided around the light emitting portion of the bioapplying surface. The bioapplied light irradiation device according to claim 2 , wherein a protective film is laminated on the photochemotherapy agent layer and the adhesive layer. The bioapplied light irradiation device according to any one of claims 1 to 3, wherein the light emitting device is an organic electroluminescence device containing an organic semiconductor. The bioapplied light irradiating device according to any one of claims 1 to 4, wherein the temperature at the time of light emission of the bioapplied light irradiating device is less than 45 ° C. The bioapplicable light irradiation device according to any one of claims 1 to 5, wherein the transmission of the ID information from the ID transmission unit to the communication unit is by wireless communication.

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