JP6924554B2 - Protective seal and protective seal set - Google Patents

Description

The present invention relates to a protective seal that can be detachably attached to a female connector having a self-closing valve body having a slit. The present invention also relates to a protective seal set in which such a protective seal is mounted on a release sheet.

In the medical field, circuits are used to transport various liquids such as chemicals, infusions, and blood. A circuit is generally formed by connecting a container, various instruments, a tube, or the like. A connector consisting of a male connector and a female connector is used to connect different members.

As a female connector used in such a field, a female connector provided with a self-closing valve body is known (see, for example, Patent Documents 1 to 5). The valve body is a circular thin plate made of a soft material having rubber elasticity, and a slit penetrating the valve body in the thickness direction is formed in the center thereof. The valve body is covered with a cap. An opening is provided in the center of the circular top plate of the cap, and the central region of the valve body including the slit is exposed to the outside world in the opening. When a tubular male lure having no sharp tip is pushed toward the slit of the valve body, the male lure can deform the valve body and penetrate the slit. As a result, the female connector and the male lure communicate with each other. After that, when the male lure is pulled out from the valve body, the valve body immediately elastically returns to the initial state and the slit is closed. The osluar can be repeatedly inserted and removed from the valve body of the female connector as many times as necessary. When the osluar does not penetrate the slit, the slit is closed in a liquid-tight and airtight manner, so that liquid may leak from the female connector to the outside world or bacteria in the outside world may invade the female connector through the slit. There is no.

JP-A-11-197254 Japanese Unexamined Patent Publication No. 2008-029607 Japanese Unexamined Patent Publication No. 2010-075684 Japanese Unexamined Patent Publication No. 2010-194105 Japanese Unexamined Patent Publication No. 2013-252165

The above-mentioned conventional female connector is effective in preventing infection because the slit of the valve body is closed in the non-connected state in which the male lure is not connected. However, in the non-connected state, the region including the slit of the valve body is exposed in the opening of the cap, and the top plate of the cap surrounding the opening is also exposed to the outside world. Therefore, these exposed valve bodies and top plates may be contaminated with bacteria. When the male lure is connected in this state, bacteria adhere to the male lure when the male lure touches the contaminated valve body or top plate of the female connector, and then the bacteria penetrate into the female connector by the male lure penetrating the slit of the valve body. Can be contaminated and cause the patient to become infected.

In order to prevent this, conventionally, (1) immediately after separating the male lure, the liquid adhering to the valve body and the top plate is wiped off for the main purpose of removing the nutritional components of bacteria, and (2) the male lure is connected. Immediately before, the valve body and the top plate were wiped and cleaned with a disinfectant for the main purpose of disinfection. As described above, conventionally, there is a problem that the work is complicated because it is necessary to perform the wiping work twice immediately after separating the male lure and immediately before connecting the male lure.

An object of the present invention is to solve the above-mentioned conventional problems and reduce the number of times of wiping work of the female connector while suppressing the possibility of bacteria being mixed into the female connector.

The protective seal of the present invention is a female connector including a self-closing valve body having a slit penetrating in the thickness direction and a top plate provided with an opening for exposing the area including the slit of the valve body. Therefore, in the medical field, it can be detachably attached to a female connector used in a circuit for transporting various liquids such as a drug solution, an infusion solution, and blood. The protective seal includes a base material layer and an adhesive layer provided on one side of the base material layer. The protective seal is configured so that the adhesive layer can be attached to the female connector with the adhesive layer on the female connector side so as to cover the valve body exposed in the opening. The protective seal includes a main portion attached to the top plate surrounding the opening. The main portion is configured so as not to protrude from the top plate when the protective seal is attached to the female connector. The adhesive layer is formed up to the outer peripheral edge of the main portion.

In the protective seal set of the present invention, the protective seal is provided on a release sheet provided with a release layer on one side.

The protective seal of the present invention can be attached to the female connector so as to cover the area of the valve body exposed in the opening of the top plate. Therefore, immediately after separating the male lure from the female connector, wipe off the liquid adhering to the valve body and top plate of the female connector, and then attach a protective seal to the female connector to reconnect the male lure to the female connector. After removing the protective seal from the female connector, it is not necessary to wipe and clean the valve body and top plate of the female connector for disinfection. Therefore, the number of times of wiping work of the female connector can be reduced while suppressing the possibility of bacteria being mixed into the female connector.

The protective seal set of the present invention makes it possible to manufacture the protective seal of the present invention easily and inexpensively. It also makes it easy to carry the protective sticker.

FIG. 1A is a plan view of a protective seal according to an embodiment of the present invention. FIG. 1B is a side view of the protective seal. FIG. 1C is an enlarged cross-sectional view of the protective seal. FIG. 2A is a perspective view showing an example of a female connector to which the protective sticker of the present invention is attached. FIG. 2B is a cross-sectional view of the female connector shown in FIG. 2A. FIG. 3 is a perspective view showing a state immediately before the protective sticker according to the embodiment of the present invention is attached to the female connector. FIG. 4 is a perspective view showing a state in which the main portion of the protective sticker according to the embodiment of the present invention is attached to the top plate of the female connector. FIG. 5 is a perspective view showing a state in which the protective sticker according to the embodiment of the present invention is attached to the female connector. FIG. 6 is a perspective view of a protective seal set in which a plurality of protective seals according to an embodiment of the present invention are formed.

The protective seal of the present invention may include a main portion and a tab protruding from the main portion. In this case, it is preferable that the protective seal is configured so that when the main portion is attached to the top plate surrounding the opening, the tab can be attached to the outer peripheral surface of the female connector. Such a configuration is advantageous in facilitating the work of attaching and peeling the protective seal to the female connector and ensuring the cleanliness of the connection surface (valve body and top plate) of the female connector.

A disinfectant may be mixed in the adhesive layer. This is advantageous in preventing the invasion of bacteria into the connecting surface of the female connector to which the protective seal is affixed.

The protective seal is preferably configured to cover the entire surface of the top plate that surrounds the opening. This is advantageous for improving the adhesive strength of the protective seal to the female connector and ensuring the cleanliness of the top plate.

The protective seal is preferably configured so that the adhesive layer does not remain on the valve body exposed in the opening after the protective seal is peeled off from the female connector. As a result, when the male lure is connected to the female connector, the possibility that the adhesive is mixed in the female connector and further flows into the patient's body can be reduced.

Hereinafter, the present invention will be described in detail with reference to suitable embodiments. However, it goes without saying that the present invention is not limited to the following embodiments. For convenience of explanation, each figure referred to in the following description is a simplified representation of the main members constituting the embodiment of the present invention. Therefore, the present invention may include any member not shown in each of the following figures. Further, within the scope of the present invention, each member shown in each of the following figures may be changed or omitted. The drawings schematically show the present invention, and the dimensions of the illustrated members do not exactly match those of the actual members.

FIG. 1A is a plan view of the protective sticker 1 according to the embodiment of the present invention, and FIG. 1B is a side view of the protective sticker 1. The protective seal 1 includes a substantially circular main portion 2 and a tab 3 protruding outward along the radial direction from the outer peripheral edge of the main portion 2.

FIG. 1C is an enlarged cross-sectional view of the protective seal 1 in a plane along the thickness direction. The protective seal 1 includes a base material layer 5 and an adhesive layer 6 provided on one side of the base material layer 5. The cross-sectional structure of the protective seal 1 is constant regardless of the position on the protective seal 1. The base material layer 5 imparts the desired mechanical strength to the protective seal 1. The adhesive layer 6 is provided for attaching the protective seal 1 to the female connector. In the present embodiment, the adhesive layer 6 is uniformly provided on one side of the protective seal 1 over the entire surface.

FIG. 2A is a perspective view of the female connector 100 to which the protective seal 1 is attached, and FIG. 2B is a cross-sectional view thereof.

The female connector 100 includes a disk-shaped valve body (sometimes referred to as a “septum”) 110, a base 120 for sandwiching and fixing the valve body 110 in the vertical direction, and a cap 130.

At the center of the valve body 110, a linear slit (cut) 111 that penetrates the valve body 110 in the thickness direction (vertical direction in FIG. 2B) is formed. The material of the valve body 110 is not limited, but is preferably a soft material having rubber elasticity, and for example, isoprene rubber, silicone rubber, butyl rubber, thermoplastic elastomer, and the like can be used.

As shown in FIG. 2B, the base 120 includes a pedestal 121 having a substantially cylindrical shape on the upper side thereof. The outer peripheral surface of the pedestal 121 is a cylindrical surface. A pair of engaging claws 122 project outward from the outer peripheral surface of the pedestal 121. Below the pedestal 121, a tubular body 127 communicating with the lumen 125 of the pedestal 121 and a female screw 128 coaxial with the tubular body 127 are provided.

The cap 130 includes a top plate 131 having a disk shape and a peripheral wall 135 having a cylindrical shape extending downward from the outer peripheral edge 131a of the top plate 131. A circular opening (through hole) 132 is formed in the center of the top plate 131. The upper surface of the top plate 131 (the surface opposite to the valve body 110) is a concave conical surface that descends as it approaches the opening 132. A pair of engaging holes 136 are formed in the peripheral wall 135 (see FIG. 2A). The engagement hole 136 is a through hole that penetrates the peripheral wall 135 in the radial direction.

The valve body 110 is placed on the upper end of the pedestal 121, and the valve body 110 is covered with the cap 130 from above. The cap 130 is engaged with the engaging claw 122 by fitting the engaging claw 122 formed in the pedestal 121 into the engaging hole 136 formed in the cap 130. Thus, the cap 130 is fixed to the base 120. The valve body 110 is sandwiched by the upper end of the pedestal 121 and the top plate 131 of the cap 130 in the thickness direction thereof. As shown in FIG. 2A, the central region of the valve body 110 including the slit 111 is exposed within the opening 132 formed in the top plate 131. The top plate 131 and the region of the valve body 110 exposed in the opening 132 form a connecting surface 101 of the female connector 100. The outer peripheral surface of the peripheral wall 135 of the cap 130 and the base 120 below it constitutes the outer peripheral surface of the female connector 100. The outer peripheral surface of the female connector 100 is a substantially cylindrical surface adjacent to the top plate 131 via the outer peripheral edge 131a of the top plate 131.

The base 120 and the cap 130 are preferably made of a hard material. Specifically, resin materials such as polyacetal, polycarbonate, polystyrene, polyamide, polypropylene, and rigid polyvinyl chloride can be used. Each of the base 120 and the cap 130 can be integrally manufactured as one part by an injection molding method or the like using these resin materials.

When a hollow tubular male lure (not shown) having no sharp tip is pressed against the valve body 110 exposed in the opening 132, the valve body 110 is deformed and the slit 111 is opened, and the male lure is slit 111. Can be inserted into. Thus, the lumen 125 of the female connector 100 and the male lure communicate with each other. When the male lure is pulled out from the valve body 110, the valve body 110 immediately returns to the initial state elastically, and the slit 111 is closed in a liquid-tight and airtight manner. In this way, the valve body 110 has a resealing property, and the male lure can be repeatedly inserted and removed. The female connector 100 provided with the self-closing valve body 110 in which the slit 111 is formed is generally called a "needleless port".

A method of using the protective seal 1 with respect to the female connector 100 will be described.

A male lure is connected to the female connector 100 to allow a liquid (for example, a chemical solution, an infusion solution, blood, etc.) to flow between the female connector 100 and the male lure, and then the male lure is separated from the female connector 100. Liquid adheres to the surface of the valve body 110 exposed in the opening 132 and the upper surface of the top plate 131 surrounding the opening 132 (that is, the connection surface 101 of the female connector 100) after the osluer is separated. Often. Wipe off this liquid adhering to the connection surface 101 with a clean cloth or the like to clean it. Preferably, the connecting surface 101 is disinfected with a disinfectant.

Next, as shown in FIG. 3, the protective seal 1 is opposed to the top plate 131 of the cap 130 of the female connector 100. The surface of the protective seal 1 provided with the adhesive layer 6 (see FIG. 1B) is opposed to the top plate 131.

Next, as shown in FIG. 4, the protective sticker 1 is attached to the top plate 131 of the cap 130. A protective sticker 1 is attached so that the main portion 2 closes the opening 132 (see FIGS. 2A and 3) provided in the top plate 131. The valve body 110 exposed in the opening 132 is covered with the protective seal 1. The adhesive layer 6 of the main portion 2 adheres to the top plate 131 of the cap 130. By pressing the main portion 2 toward the female connector 100, the main portion 2 can be curved in a concave shape along the concave conical surface of the top plate 131. As a result, the adhesive layer 6 of the main portion 2 can be adhered to the top plate 131 over a wider area, so that the opening 132 is more reliably sealed by the main portion 2. The tab 3 of the protective seal 1 projects outward from the outer peripheral edge 131a (see FIGS. 2A and 3) of the top plate 131. The work of attaching the protective sticker 1 can be easily performed by pinching the tab 3.

Finally, as shown in FIG. 5, the tab 3 protruding from the outer peripheral edge 131a of the top plate 131 is bent along the outer peripheral edge 131a, and the tab 3 is bent into the peripheral wall 135 of the cap 130 (that is, the female connector 100). Attach it to the outer peripheral surface of. The female connector 100 is left with the protective seal 1 affixed in this way until the male lure is subsequently reconnected.

The protective seal 1 is peeled off from the female connector 100 immediately before the male lure is reconnected to the female connector 100. First, the tab 3 is peeled off from the peripheral wall 135 of the cap 130, and then the tab 3 is picked and the protective seal 1 is pulled, so that the protective seal 1 can be easily separated from the female connector 100. After that, an male lure (not shown) is inserted into the slit 111 of the valve body 110 exposed in the opening 131. The protective seal 1 peeled off from the female connector 100 is discarded.

As described above, in the present embodiment, immediately after separating the male lure from the female connector 100, the liquid adhering to the connection surface 101 of the female connector 100 is wiped off. Preferably, the connecting surface 101 is disinfected with a disinfectant solution. Immediately after that, the protective sticker 1 is attached to the connection surface 101. The adhesive layer 6 of the protective seal 1 is in close contact with the top plate 131, and the region of the valve body 110 exposed in the opening 132 is covered with the protective seal 1. Since the protective seal 1 prevents the ingress of bacteria, dust, water and the like, the area of the valve body 110 is maintained in a clean state. Therefore, after that, the protective seal 1 can be peeled off from the female connector 100, and the male lure can be immediately connected to the female connector 100. Immediately before reconnecting the male connector 100 to the female connector 100, it is not necessary to wipe and clean the connection surface 101 of the female connector 100 with a disinfectant.

As described above, conventionally, the female connector 100 in the non-connected state is left in a state where the connecting surface 101 of the female connector 100 is exposed. Therefore, immediately after separating the male lure from the female connector 100, in addition to wiping and cleaning the liquid adhering to the connection surface 101 of the female connector 100, after that, immediately before reconnecting the male lure to the female connector 100, the connection surface 101 It was necessary to wipe it off with a disinfectant. On the other hand, in the present embodiment, since the protective sticker 1 is continuously attached to the female connector 100 in the non-connected state, the clean state of the connecting surface 101 of the female connector 100 is maintained. Therefore, it is not necessary to wipe and clean the connection surface 101 with a disinfectant immediately before reconnecting the male lure to the female connector 100. Therefore, the number of times of wiping work of the female connector 100 can be reduced while suppressing the possibility of bacteria being mixed into the female connector 100.

In the present embodiment, it is necessary to attach the protective sticker 1 to the female connector 100 and to peel off the protective sticker 1 from the female connector 100. Instead, as described above, the conventional work of wiping and cleaning the connection surface 101 immediately before reconnecting the male lure can be omitted. The work of attaching and peeling off the protective sticker 1 is extremely simple as compared with the work of wiping and cleaning the connection surface 101. Therefore, the work load of the worker is remarkably reduced as a whole.

The work of attaching the protective sticker 1 to the female connector 100 and the work of peeling it off can be easily performed by pinching the tab 3 with a finger. Further, since the sticking operation is performed by picking the tab 3, the operator's finger does not touch the main portion 2 (particularly the surface on the adhesive layer 6 side thereof). Therefore, the possibility that the bacteria adhering to the finger adheres to the main portion 2 and further adheres to the wiped and cleaned connection surface 101 of the female connector 100 is reduced. Further, by first peeling the tab 3 from the peripheral wall 135 of the cap 130 and then pinching the tab 3, the operator's finger does not touch the connection surface 101 of the female connector 100. Therefore, the possibility that bacteria adhering to the finger adheres to the connection surface 101 of the female connector 100 is reduced. As described above, the tab 3 is advantageous not only for facilitating the sticking work and peeling work of the protective seal 1, but also for ensuring the cleanliness of the connection surface 101 of the female connector 100. .. This further reduces the likelihood that the patient will develop an infection.

As shown in FIG. 6, the protective seal 1 can be provided as a protective seal set 10 in which the protective seal 1 is detachably formed on the release sheet 11. The release sheet 11 is provided with a release layer on one side of a base sheet made of paper or resin. The adhesive layer 6 and the base material layer 5 are laminated in this order on the release layer of the release sheet 11. After that, the protective seal 1 can be formed on the release sheet 11 by half-cut processing. By using a long release sheet and dividing the long release sheet at the same time as half-cut processing, a protective seal set 10 in which one or more protective seals 1 are mounted on the release sheet 11 is formed. Can be manufactured. By using such a manufacturing method, a large amount of protective seal 1 can be manufactured easily and inexpensively. Since the protective seal set 10 is a thin and flexible sheet-like material, it is easy to carry a plurality of protective seal sets 10. For example, in a medical institution such as a hospital, a nurse always carries a plurality of protective sticker sets 10, peels the protective sticker 1 from the protective sticker set 10 when necessary, and attaches the protective sticker 1 to the female connector 100. Is possible.

Unlike the present invention, a cover (cap) having a bottomed tubular shape that can be detachably attached to the female connector 100 in a non-connected state so as to cover the connection surface 101 is actually commercially available. This cover is expensive because it is a resin molded product and is a disposable type. Moreover, because of its size, it is bulky and inconvenient for nurses to carry multiple covers. The protective seal 1 and the protective seal set 10 of the present embodiment do not have such a problem of the cover.

The base material layer 5 of the protective seal 1 may be made of a resin sheet. The material constituting the base material layer 5 is not limited, but a polymer resin material such as polyester, polyethylene, polypropylene, polyurethane, ethylene vinyl acetate, or polyethylene terephthalate can be used. The base material layer 5 does not have to be a single layer, and may have a multilayer structure in which a plurality of layers are laminated. The surface of the base material layer 5 opposite to the adhesive layer 6 may be printed or colored. There is no limitation on the thickness of the base material layer 5. However, if the base material layer 5 is too thin, the mechanical strength of the protective seal 1 is lowered, so that the protective seal 1 is easily torn. Further, if the base material layer 5 is too thick, the mechanical strength of the protective seal 1 becomes high, so that when the tab 3 is bent (see FIG. 5), it is difficult for the tab 3 to have a crease, and the tab 3 is attached to the peripheral wall 135 of the cap 130. It becomes difficult to attach to.

The adhesive layer 6 is not limited, but may be composed of a known adhesive such as silicon-based, acrylic-based, or rubber-based. After the protective sticker 1 is attached to the female connector 100, it is relatively easy to peel off the protective sticker 1 from the female connector 100, and the adhesive layer 6 is configured so that the adhesive does not remain on the female connector 100 after peeling. It is preferable to be done. In particular, if the adhesive adheres to the surface of the valve body 110 in the opening 135 after the protective seal 1 is peeled off, then when the male lure is inserted into the slit 111, the adhesive adhered to the valve body 110 is female. It may get mixed in the lumen 125 of the connector 100. The method for preventing the adhesive from adhering to the valve body 110 is not limited, but for example, (1) the adhesive layer 6 is not formed in the region of the protective seal 1 corresponding to the opening 132, and (2) the valve body 110. Depending on the material difference between the cap 130 and the cap 130, a method such as selecting an adhesive that does not adhere to the valve body 110 and selectively adheres to the cap 130 can be adopted.

A disinfectant may be mixed in the adhesive layer 6. As the disinfectant, for example, chlorhexidine can be used without limitation. Since the adhesive layer 6 containing the disinfectant has a disinfecting effect, by attaching the protective sticker 1 to the connection surface 101 of the female connector 100, it is possible to prevent bacteria from invading the connection surface 101 and infect the patient with bacteria. Can be reduced.

In the above embodiment, the outer diameter of the main portion 2 is substantially the same as the outer diameter of the top plate 131, but the present invention is not limited to this. However, the protective seal 1 needs to have a size sufficient to close the opening 132 of the top plate 131. Further, when the protective sticker 1 is attached to the female connector 100, if the amount of protrusion of the protective sticker 1 (particularly the main portion 2) from the outer peripheral edge 131a of the top plate 131 is large, the protective sticker 1 is intended from the top plate 131. Easy to peel off without. Therefore, preferably, the main portion 2 is larger than the opening 132 of the top plate 131 and is the same as or smaller than the top plate 131. More preferably, the main portion 2 has substantially the same dimensions as the top plate 131. As a result, the main portion 2 can cover the entire surface of the top plate 131 without protruding from the top plate 131. This is advantageous for improving the adhesive strength of the main portion 2 to the female connector 100 and ensuring the cleanliness of the top plate 131. Generally, the outer diameter of the main portion 2 is not limited, but is preferably 4.0 mm or more, more preferably 4.2 mm or more, and 13.1 mm or less, further 11.7 mm or less. Is preferable. From the same viewpoint, the area of the main portion 2 is not limited, but may be 10% or more, moreover 50% or more of the area (including the area in the opening 132) of the top plate 131 when viewed in a plan view. It is preferable, and it is preferably 100% or less, more preferably 90% or less.

The plan view shape of the main portion 2 does not have to be circular, and may be a polygon (for example, a regular polygon such as a regular hexagon or a regular octagon), an ellipse, or any shape.

The shape and dimensions (width, length) of the tab 3 are arbitrary. For example, in order to improve the gripability of the tab 3 or to improve the adhesive strength of the tab 3 to the outer peripheral surface of the female connector 100, the width is widened to the tip of the tab 3 (the end on the half body side of the main portion 2). The portion may be provided. The number of tabs 3 provided on the protective seal 1 does not have to be one, and may be two or more. Tab 3 may be omitted.

The number of protective stickers 1 provided in one protective sticker set 10 is not limited, and may be one, or any number of two or more. In the protective seal set 10 of FIG. 6, the portion of the base material layer 5 and the adhesive layer 6 on the release sheet 11 other than the protective seal 1 was removed, but the protective seal set of the present invention is the release sheet 11. The adhesive layer 6 and the base material layer 5 uniformly provided on the entire surface of the protective seal 1 may be simply half-cut into the shape of the protective seal 1.

The configuration of the female connector to which the protective seal of the present invention is attached is not limited to the above embodiment. The protective seal of the present invention can be attached to any female connector provided with a self-closing valve body having a slit. In the above embodiment, the tab 3 is attached to the peripheral wall 135 of the cap 130 (see FIG. 5), but depending on the shape and dimensions of the peripheral wall 135, the tab 3 is not the peripheral wall 135 but the base 120. It may be affixed to the outer peripheral surface of the. The female connector 100 includes a tubular body 127 (see FIG. 2B) and is configured to be connectable to the end of the tube. The female connector to which the protective seal of the present invention is attached is not limited to this, and may be a so-called mixed injection port provided in the middle of a tube through which a liquid flows, as described in Patent Documents 1 to 3, for example. Alternatively, it may be a female connector provided in the port of the container as described in Patent Document 4.

The present invention can be used in any field in which a female connector with a self-closing valve body having a slit is used. In particular, it can be preferably used as a protective seal that can be detachably attached to a female connector used in the medical field.

1 Protective seal 2 Main part 3 Tab 5 Base material layer 6 Adhesive layer 10 Protective seal set 11 Release sheet 100 Female connector 110 Valve body 111 Slit 130 Cap 131 Top plate 132 Opening 135 Cap peripheral wall (outer surface of female connector)

Claims (6)

A female connector including a self-closing valve body having a slit penetrating in the thickness direction and a top plate provided with an opening for exposing a region of the valve body including the slit , in the medical field. It is a protective seal that can be detachably attached to a female connector used in a circuit for transporting various liquids such as chemicals, infusions, and blood.
The protective seal includes a base material layer and an adhesive layer provided on one side of the base material layer.
It is configured so that the adhesive layer can be attached to the female connector with the adhesive layer on the female connector side so as to cover the valve body exposed in the opening.
The protective seal comprises a main portion affixed to the top plate surrounding the opening.
The main portion is configured so as not to protrude from the top plate when the protective seal is attached to the female connector.
The protective seal is characterized in that the adhesive layer is formed up to the outer peripheral end of the main portion. The protective seal further comprises a tab protruding from the main part.
The protective sticker according to claim 1, wherein when the main portion is attached to the top plate surrounding the opening, the tab can be attached to the outer peripheral surface of the female connector. The protective seal according to claim 1 or 2, wherein a disinfectant is mixed in the adhesive layer. The protective seal according to any one of claims 1 to 3, which is configured to cover the entire surface of the top plate surrounding the opening. The protective seal according to any one of claims 1 to 4, which is configured so that the adhesive layer does not remain on the valve body exposed in the opening after the protective seal is peeled off from the female connector. .. A protective seal set in which the protective seal according to any one of claims 1 to 5 is provided on a release sheet provided with a release layer on one side.

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