JP6860575B2 - 神経変性障害の処置に用いられるホメオタンパク質 - Google Patents
神経変性障害の処置に用いられるホメオタンパク質 Download PDFInfo
- Publication number
- JP6860575B2 JP6860575B2 JP2018534025A JP2018534025A JP6860575B2 JP 6860575 B2 JP6860575 B2 JP 6860575B2 JP 2018534025 A JP2018534025 A JP 2018534025A JP 2018534025 A JP2018534025 A JP 2018534025A JP 6860575 B2 JP6860575 B2 JP 6860575B2
- Authority
- JP
- Japan
- Prior art keywords
- neurons
- mice
- ohda
- disease
- snpc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15306482.9 | 2015-09-23 | ||
| EP15306482 | 2015-09-23 | ||
| PCT/EP2016/072675 WO2017071889A1 (en) | 2015-09-23 | 2016-09-23 | Homeoproteins for use in the treatment of neurodegenerative disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018536697A JP2018536697A (ja) | 2018-12-13 |
| JP2018536697A5 JP2018536697A5 (https=) | 2019-09-05 |
| JP6860575B2 true JP6860575B2 (ja) | 2021-04-14 |
Family
ID=54207439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018534025A Active JP6860575B2 (ja) | 2015-09-23 | 2016-09-23 | 神経変性障害の処置に用いられるホメオタンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20190247461A1 (https=) |
| EP (2) | EP3352777B1 (https=) |
| JP (1) | JP6860575B2 (https=) |
| CN (1) | CN108289929A (https=) |
| ES (2) | ES2895154T3 (https=) |
| PL (2) | PL3960195T3 (https=) |
| WO (1) | WO2017071889A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120676931A (zh) | 2023-01-13 | 2025-09-19 | 布瑞恩维公司 | Engrailed蛋白的稳定水性组合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662698A1 (fr) | 1990-06-05 | 1991-12-06 | Centre Nat Rech Scient | Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite. |
| FR2855178B1 (fr) * | 2003-05-20 | 2005-08-05 | Centre Nat Rech Scient | Peptides modulateurs de l'activite du facteur de transcription engrailed |
| FR2897780B1 (fr) | 2006-02-28 | 2008-05-23 | Centre Nat Rech Scient | Utilisation de la proteine a homeodomaine engrailed comme anxiolytique |
| GB0625321D0 (en) * | 2006-12-19 | 2007-01-24 | Univ Surrey | Cancer biomarker |
| FR2926023B1 (fr) | 2008-01-09 | 2010-02-26 | Centre Nat Rech Scient | Utilisation d'une homoproteine de la famille bicoid pour le traitement du glaucome. |
| RU2012100903A (ru) * | 2009-07-13 | 2013-08-20 | Зе Юниверсити Оф Саррей | Терапевтические пептиды, полипептиды и последовательности нуклеиновых кислот |
| WO2013128239A1 (en) * | 2012-02-29 | 2013-09-06 | Centre National De La Recherche Scientifique | Use of engrailed for increasing dopamine synthesis by dopaminergic neurons |
-
2016
- 2016-09-23 EP EP16777596.4A patent/EP3352777B1/en active Active
- 2016-09-23 CN CN201680059070.1A patent/CN108289929A/zh active Pending
- 2016-09-23 PL PL21189549.5T patent/PL3960195T3/pl unknown
- 2016-09-23 PL PL16777596T patent/PL3352777T3/pl unknown
- 2016-09-23 EP EP21189549.5A patent/EP3960195B1/en active Active
- 2016-09-23 JP JP2018534025A patent/JP6860575B2/ja active Active
- 2016-09-23 US US15/761,702 patent/US20190247461A1/en not_active Abandoned
- 2016-09-23 ES ES16777596T patent/ES2895154T3/es active Active
- 2016-09-23 ES ES21189549T patent/ES3010130T3/es active Active
- 2016-09-23 WO PCT/EP2016/072675 patent/WO2017071889A1/en not_active Ceased
-
2021
- 2021-06-16 US US17/349,746 patent/US20210379144A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3960195B1 (en) | 2025-01-08 |
| JP2018536697A (ja) | 2018-12-13 |
| PL3352777T3 (pl) | 2022-02-07 |
| EP3352777A1 (en) | 2018-08-01 |
| EP3960195A1 (en) | 2022-03-02 |
| WO2017071889A1 (en) | 2017-05-04 |
| CA2999209A1 (en) | 2017-05-04 |
| CN108289929A (zh) | 2018-07-17 |
| US20210379144A1 (en) | 2021-12-09 |
| ES3010130T3 (en) | 2025-04-01 |
| US20190247461A1 (en) | 2019-08-15 |
| PL3960195T3 (pl) | 2025-06-09 |
| ES2895154T3 (es) | 2022-02-17 |
| EP3352777B1 (en) | 2021-09-15 |
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