JP6814132B2 - 内部タンパク質タグ - Google Patents

内部タンパク質タグ Download PDF

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Publication number
JP6814132B2
JP6814132B2 JP2017514354A JP2017514354A JP6814132B2 JP 6814132 B2 JP6814132 B2 JP 6814132B2 JP 2017514354 A JP2017514354 A JP 2017514354A JP 2017514354 A JP2017514354 A JP 2017514354A JP 6814132 B2 JP6814132 B2 JP 6814132B2
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Japan
Prior art keywords
polypeptide
internal
protein
amino acid
seq
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JP2017514354A
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English (en)
Japanese (ja)
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JP2017533181A (ja
JP2017533181A5 (enExample
Inventor
アンドリュー エス ディクソン
アンドリュー エス ディクソン
ランス ピー エンセル
ランス ピー エンセル
トーマス マヒレイド
トーマス マヒレイド
マリー シュウィン
マリー シュウィン
キース ウッド
キース ウッド
モニカ ウッド
モニカ ウッド
クリス ツィマーマン
クリス ツィマーマン
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Promega Corp
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Promega Corp
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Publication of JP2017533181A5 publication Critical patent/JP2017533181A5/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y308/00Hydrolases acting on halide bonds (3.8)
    • C12Y308/01Hydrolases acting on halide bonds (3.8) in C-halide substances (3.8.1)
    • C12Y308/01005Haloalkane dehalogenase (3.8.1.5)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
JP2017514354A 2014-09-12 2015-09-11 内部タンパク質タグ Active JP6814132B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462049875P 2014-09-12 2014-09-12
US62/049,875 2014-09-12
PCT/US2015/049741 WO2016040835A1 (en) 2014-09-12 2015-09-11 Internal protein tags

Publications (3)

Publication Number Publication Date
JP2017533181A JP2017533181A (ja) 2017-11-09
JP2017533181A5 JP2017533181A5 (enExample) 2018-10-18
JP6814132B2 true JP6814132B2 (ja) 2021-01-13

Family

ID=55459623

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017514354A Active JP6814132B2 (ja) 2014-09-12 2015-09-11 内部タンパク質タグ

Country Status (4)

Country Link
US (1) US9969991B2 (enExample)
EP (2) EP3191601B1 (enExample)
JP (1) JP6814132B2 (enExample)
WO (1) WO2016040835A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2926463T3 (es) 2013-03-15 2022-10-26 Promega Corp Activación de la bioluminiscencia mediante complementación estructural
US11365402B2 (en) 2014-09-12 2022-06-21 Promega Corporation Internal protein tags
EP3191601B1 (en) 2014-09-12 2022-11-02 Promega Corporation Internal protein tags
JP2021526832A (ja) * 2018-06-12 2021-10-11 プロメガ コーポレイションPromega Corporation 多分子ルシフェラーゼ
JP2020080784A (ja) * 2018-11-29 2020-06-04 シスメックス株式会社 融合ポリペプチド、融合ポリペプチドの製造方法、及び融合ポリペプチドをコードするdna
EP3953374A4 (en) * 2019-04-10 2023-06-07 Promega Corporation COMPOSITIONS AND METHODS FOR DETECTION OF ANALYTES USING BIOLUMINESCENCE
US11360096B2 (en) 2019-05-16 2022-06-14 Duke University Complex BRET technique for measuring biological interactions
US11591633B2 (en) * 2019-09-11 2023-02-28 Laboratory Corporation Of America Holdings Methods and systems for the rapid detection of bacteria using recombinant bacteriophage to express an indicator subunit
CN110592031B (zh) * 2019-09-25 2023-03-14 华南农业大学 一株S蛋白融合HiBiT的传染性支气管炎重组病毒及制备方法与应用
JP2023520359A (ja) 2020-03-25 2023-05-17 エラスムス・ユニヴァーシティ・メディカル・センター・ロッテルダム 放射性核種イメージングのためのレポーター系
JP2025515181A (ja) * 2022-05-04 2025-05-13 プロメガ コーポレイション 伸長表面ループ領域を有する修飾デハロゲナーゼ
US20240368565A1 (en) * 2023-05-04 2024-11-07 Promega Corporation Complementation-based tags and reporters for dual-modality labeling

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914095A (en) 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
US5368484A (en) 1992-05-22 1994-11-29 Atari Games Corp. Vehicle simulator with realistic operating feedback
KR950703582A (ko) 1992-10-14 1995-09-20 조이스 이. 마임스 킬레이트화 중합체(chelating polymers)
GB9503969D0 (en) 1995-02-28 1995-04-19 Sams Bernard Incrementing mechanism
US7268229B2 (en) 2001-11-02 2007-09-11 Promega Corporation Compounds to co-localize luminophores with luminescent proteins
WO2007041251A2 (en) * 2005-09-30 2007-04-12 Montana State University System for detecting protein-protein interactions
KR101665352B1 (ko) * 2009-05-01 2016-10-12 프로메가 코포레이션 광 출력이 향상된 합성 오플로포러스 루시퍼라제
AU2011323418B2 (en) * 2010-11-02 2017-07-27 Promega Corporation Novel coelenterazine substrates and methods of use
US10024862B2 (en) * 2012-12-12 2018-07-17 Promega Corporation Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
ES2926463T3 (es) * 2013-03-15 2022-10-26 Promega Corp Activación de la bioluminiscencia mediante complementación estructural
EP3191601B1 (en) 2014-09-12 2022-11-02 Promega Corporation Internal protein tags

Also Published As

Publication number Publication date
US9969991B2 (en) 2018-05-15
EP3191601A1 (en) 2017-07-19
EP4219736A1 (en) 2023-08-02
EP3191601A4 (en) 2018-04-04
EP3191601B1 (en) 2022-11-02
JP2017533181A (ja) 2017-11-09
US20160097042A1 (en) 2016-04-07
WO2016040835A1 (en) 2016-03-17

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