JP6807279B2 - Extra systole discrimination device, extra systole discrimination method and program - Google Patents

Extra systole discrimination device, extra systole discrimination method and program Download PDF

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JP6807279B2
JP6807279B2 JP2017109807A JP2017109807A JP6807279B2 JP 6807279 B2 JP6807279 B2 JP 6807279B2 JP 2017109807 A JP2017109807 A JP 2017109807A JP 2017109807 A JP2017109807 A JP 2017109807A JP 6807279 B2 JP6807279 B2 JP 6807279B2
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extra systole
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佳那 江口
佳那 江口
良輔 青木
良輔 青木
吉田 和広
和広 吉田
山田 智広
智広 山田
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Nippon Telegraph and Telephone Corp
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この発明は、期外収縮判別装置、期外収縮判別方法及びプログラムに関する。 The present invention relates to an extra systole discriminating device, an extra systole discriminating method and a program.

従来より被験者の生体情報である心電波形の解析システムが広く知られている。まず、最初に、このような心電波形の解析分野における理解の前提条件について簡単に説明する。
1 心臓の活動
心臓は、心臓そのものでひとつのリズムを持っている訳ではなく、心臓の各部が固有のリズムをもっている。正常な状態であれば、各部は洞調律と呼ばれる洞結節のリズム(60〜100回/分)にしたがって動く。
Conventionally, an electrocardiographic waveform analysis system, which is biological information of a subject, has been widely known. First, the preconditions for understanding in the field of electrocardiographic waveform analysis will be briefly described.
1 Heart activity The heart does not have one rhythm in itself, but each part of the heart has its own rhythm. Under normal conditions, each part moves according to the rhythm of the sinus node (60 to 100 times / minute) called sinus rhythm.

心臓の正常なリズムは、洞結節→房室結節→His束→左右の脚→プルキンエ繊維の順番に伝わり、この過程で心房筋、心室筋を刺激して規則的な収縮を引き起こす。心電図は、洞結節が属する心房の興奮および心室の収縮を可視化することができる。心電図で見られる波形にはP波、QRS群、T波、U波が挙げられる。このうち、P波が心房の興奮を反映する。心室収縮では、一回の収縮で脱分極と再分極の二種類の現象が順に観測される。この脱分極を反映するのがQRS群であり、T波は再分極を反映する(参考文献[i]参照)。 The normal rhythm of the heart is transmitted in the order of sinus node → atrioventricular node → His bundle → left and right legs → Purkinje fiber, and in this process, it stimulates the atrial and ventricular muscles to cause regular contraction. An electrocardiogram can visualize the excitement of the atrium to which the sinus node belongs and the contraction of the ventricles. Waveforms seen on the electrocardiogram include P wave, QRS complex, T wave, and U wave. Of these, the P wave reflects the excitement of the atrium. In ventricular contraction, two types of phenomena, depolarization and repolarization, are observed in sequence in one contraction. It is the QRS complex that reflects this depolarization, and the T wave reflects the repolarization (see reference [i]).

心電図の波形のうち、もっとも簡便に特徴を捉えやすいのが、心臓の脱分極活動を反映するQRS群である。QRS群の正常値は、持続時間0.10[sec]以下かつ、電位3.5[mV]ないし4.0[mV]以下である(参考文献[i],[ii])。 Of the ECG waveforms, the QRS complex, which reflects the depolarizing activity of the heart, is the easiest to capture the features. The normal value of the QRS complex is 0.10 [sec] or less in duration and 3.5 [mV] to 4.0 [mV] or less in potential (references [i], [ii]).

QRS群を構成する波形のうち、Q波、S波は陰性波であり、R波のみが陽性波である。R波はQ波、S波よりも視認が容易であることから、隣接する2つのR波の間隔であるR−R Interval(RRI)が瞬時心拍の算出に用いられる事が多い(参考文献[i]−[iii])。通常は、このように算出した瞬時心拍や、瞬時心拍から求まる平均心拍数が洞調律になっているかを評価する。図5は、R波及びRRIの関係を示す図である。
2 不整脈と期外収縮
正常な脈とは,P−QRS−Tのパターンが同じ形で揃っていて、その間隔がおおよそ規則的、かつ心拍数が60〜100回/分である状態を指す。この三つの特徴のいずれかを失ったものが不整脈と呼ばれる。
Of the waveforms that make up the QRS complex, the Q wave and S wave are negative waves, and only the R wave is a positive wave. Since the R wave is easier to see than the Q wave and the S wave, the R-R Interval (RRI), which is the interval between two adjacent R waves, is often used to calculate the instantaneous heartbeat (reference [Reference]. i]-[iii]). Usually, it is evaluated whether the instantaneous heart rate calculated in this way or the average heart rate obtained from the instantaneous heart rate is sinus rhythm. FIG. 5 is a diagram showing the relationship between the R wave and the RRI.
2 Arrhythmia and extra systole A normal pulse refers to a state in which the P-QRS-T pattern is aligned in the same shape, the intervals are approximately regular, and the heart rate is 60 to 100 beats / minute. Those who lose one of these three characteristics are called arrhythmias.

不整脈のひとつに期外収縮がある。期外収縮では、規則的な瞬時心拍に割り込むQRS群が観察され、割り込んだQRS群とその前後のQRS群とで構成される瞬時心拍が洞調律からはずれる場合が多い。図6は、期外収縮の一例を示す図である。 One of the arrhythmias is extra systole. In extrasystoles, a QRS complex that interrupts a regular instantaneous heartbeat is observed, and the instantaneous heartbeat composed of the interrupted QRS complex and the QRS complex before and after it often deviates from sinus rhythm. FIG. 6 is a diagram showing an example of extra systole.

期外収縮は、上室性期外収縮と心室性期外収縮に大別される。一般に、上室性期外収縮のQRS群は正常のQRS群とほぼ同様の形状だが、心室性期外収縮のQRS群は正常と異なる形状となる場合が多い(参考文献[i],[ii]参照)。図7は、上室性期外収縮で見られるQRS群を示す図であり、図8は、心室性期外収縮で見られるQRS群を示す図である。
3 ウェアラブル心電図計測について
心電図を計測する手段のひとつとして、ホルター心電計などのウェアラブルなデバイスがある。これらのデバイスを用いて取得する心電図は、電極の変形やズレをはじめとする電極異常あるいは、体動、発汗、静電気など様々な要因によって計測異常が生じる(参考文献[iv]参照)。この計測異常は、心電図では図9に示すようなアーチファクトやノイズという形で確認できる。
Extrasystoles are broadly divided into supraventricular extrasystoles and ventricular extrasystoles. In general, the QRS complex with supraventricular extrasystoles has almost the same shape as the normal QRS complex, but the QRS complex with ventricular extrasystoles often has a different shape from normal (references [i], [ii]. ]reference). FIG. 7 is a diagram showing a QRS complex observed in supraventricular extrasystoles, and FIG. 8 is a diagram showing a QRS complex observed in ventricular extrasystoles.
3 Wearable ECG measurement As one of the means for measuring an electrocardiogram, there is a wearable device such as a Holter electrocardiograph. In the electrocardiogram acquired using these devices, measurement abnormalities occur due to electrode abnormalities such as electrode deformation and displacement, or measurement abnormalities due to various factors such as body movement, sweating, and static electricity (see Reference [iv]). This measurement abnormality can be confirmed on the electrocardiogram in the form of artifacts and noise as shown in FIG.

図9に示した通り、アーチファクトとして観測される波形はR波と類似しており、ひとつ以上連続して観測される、このため、心電図を解析してR波を抽出するアルゴリズムがアーチファクトをR波と誤判断して抽出してしまう場合もある(以降では、このようなR波を計測異常R波と呼ぶ、計測異常R波をひとつ以上含むRRIを計測異常RRIと呼ぶ)。
計測異常のひとつであるアーチファクトをR波と誤判断したものは、その発生機序から心臓の脱分極活動を一切反映しない。このため、解析対象となる瞬時心拍を構成するR波のうち、少なくともひとつがアーチファクトをR波と誤判断したものである場合、そのRRIの持続時間が洞調律よりも短かったとしても期外収縮であるとは言えない。
従来の手法
不整脈を検出する手法として、Apple Watch(登録商標)などで測定した脈拍数を用いるものがある。この手法では、心拍変動解析のピーク周波数が0.003〜0.04、0.04〜0.15、0.15〜0.4[Hz]に出現することに基づき、Apple Watchなどで計測した脈拍数を周波数解析して得られるピーク周波数と、健常者のピーク周波数とを比較して心房細動の患者を特定する。
As shown in FIG. 9, the waveform observed as an artifact is similar to the R wave, and one or more are observed continuously. Therefore, the algorithm that analyzes the electrocardiogram and extracts the R wave makes the artifact an R wave. (Hereinafter, such an R wave is referred to as a measurement abnormality R wave, and an RRI including one or more measurement abnormality R waves is referred to as a measurement abnormality RRI).
An artifact that is one of the measurement abnormalities is misjudged as an R wave, and does not reflect the depolarizing activity of the heart at all due to its generation mechanism. Therefore, if at least one of the R waves constituting the instantaneous heartbeat to be analyzed is erroneously determined to be an R wave, the RRI duration is shorter than the sinus rhythm, but extra systole. It cannot be said that.
4 Conventional method As a method for detecting arrhythmia, there is a method using a pulse rate measured by Apple Watch (registered trademark) or the like. In this method, based on the fact that the peak frequency of the heart rate variability analysis appears in 0.003 to 0.04, 0.04 to 0.15, and 0.15 to 0.4 [Hz], it was measured by Apple Watch or the like. Patients with atrial fibrillation are identified by comparing the peak frequency obtained by frequency analysis of the pulse rate with the peak frequency of healthy subjects.

Insight Data, “Detecting heart arrhythmias using machine learning and Apple Watch data,” 検索URL:https://blog.insightdatascience.com/detecting−heart−arrhythmias−using−machine−learning−and−apple−watch−data−84bc97f30d3e (平成29年5月1日検索)Insight Data, "Detecting heart arrhythmia learning machine learning and Apple Watch data," Search URL: https://blog. insightdatascience. com / detecting-heart-arrhythmia-using-machine-learning-and-apple-watch-data-84bc97f30d3e (searched on May 1, 2017)

脈波は、心臓と血管の影響を受けて変動するため、心拍数と等しいとは言えない.心拍変動解析は、瞬時心拍であるRRIを利用した解析を行うことを前提としているため、対象とするピーク周波数をそのまま脈拍の解析に使用しても良いとは限らない。 The pulse wave is not equal to the heart rate because it fluctuates under the influence of the heart and blood vessels. Since the heart rate variability analysis is premised on performing analysis using RRI, which is an instantaneous heartbeat, the target peak frequency may not always be used as it is for pulse analysis.

一般的に、心電図では期外収縮を捉えられるが、脈波では捉えられない場合がある(参考文献[v])。このような場合は脈波から求めた脈拍と、心電図から求めた心拍が一致しないため、脈拍から心臓の異常を推定することは原理的に不可能となる。 In general, extrasystoles can be captured by electrocardiogram, but may not be captured by pulse waves (reference [v]). In such a case, since the pulse obtained from the pulse wave and the heartbeat obtained from the electrocardiogram do not match, it is impossible in principle to estimate the abnormality of the heart from the pulse.

期外収縮の回数が少ない場合は心拍数の変化が少ないため、脈拍数の代わりに心拍数を用いて周波数解析を行っても異常を検出できない可能性が高い。従来手法では計測器の異常が考慮されていない。すなわち、計測異常R波を解析対象から除外できないため、計測異常R波が不整脈とみなされる頻度で生じている場合と、被験者で不整脈が生じている状態とを区別することは不可能である。 When the number of extra systoles is small, the change in heart rate is small, so there is a high possibility that abnormalities cannot be detected even if frequency analysis is performed using heart rate instead of pulse rate. The conventional method does not consider the abnormality of the measuring instrument. That is, since the measurement abnormality R wave cannot be excluded from the analysis target, it is impossible to distinguish between the case where the measurement abnormality R wave occurs at a frequency regarded as an arrhythmia and the state where the subject has an arrhythmia.

本発明は、上記実情に鑑みてなされたものであり、計測異常状態と、正常計測状態とを判別した上で、期外収縮を判別することできる期外収縮判別装置、期外収縮判別方法及びプログラムを提供することを目的とする。 The present invention has been made in view of the above circumstances, and is an extra systole discriminating device and an extra systole discriminating method capable of discriminating an extra systole after discriminating between a measurement abnormal state and a normal measurement state. And the purpose of providing the program.

本発明の第1態様は、期外収縮判別装置が、心電データから得られるR波の計測状態が正常であるときに、前記計測状態が正常であるR波を含むQRS群を評価対象となる評価対象QRS群として決定する評価対象QRS群決定手段と、
前記評価対象QRS群および前記評価対象QRS群に時間的に隣り合う隣接QRS群が、過去に生起したQRS群が有する洞調律の範囲にあるか否か、ならびに前記評価対象QRS群および前記隣接QRS群が、心臓が生理的にとり得る範囲内で生起しているか否かに基づいて、前記評価対象QRS群が期外収縮候補であるか否かを判定する期外収縮候補判定手段と、を具備する。
In the first aspect of the present invention, when the extra systole discriminating device has a normal measurement state of the R wave obtained from the electrocardiographic data, the QRS group including the R wave whose measurement state is normal is evaluated. Evaluation target QRS group determination means to be determined as an evaluation target QRS group,
The evaluation object QRS complex and the adjacent QRS complex adjacent to the evaluation object QRS complex in time is, whether it is in the range of sinus rhythm with is a QRS complex occurs in the past, as well as the evaluation object QRS group and the adjacent QRS A means for determining an extra systole candidate for determining whether or not the QRS complex to be evaluated is an extra systole candidate based on whether or not the group occurs within the physiologically possible range of the heart. To do.

本発明の第2態様は、第1態様において、前記期外収縮候補であると判定された評価対象QRS群で示される期外収縮の種別を判別する種別判別手段をさらに具備する。 A second aspect of the present invention further includes, in the first aspect, a type determination means for determining the type of extrasystole indicated by the evaluation target QRS group determined to be the extrasystole candidate.

本発明の第3態様は、第1態様において、前記期外収縮候補判定手段は、前記評価対象QRS群が所定の洞調律の範囲外、且つ前記隣接QRS群が前記評価対象QRS群に対して所定の時間内に生起している場合に、前記評価対象QRS群が前記期外収縮候補であると判定る。 In the third aspect of the present invention, in the first aspect, the extra systole candidate determination means means that the evaluation target QRS complex is outside the predetermined sinus rhythm range and the adjacent QRS group is relative to the evaluation target QRS complex. If you are occurring within a predetermined time, it determined that the evaluation object QRS complex is the extrasystole candidates.

本発明の第4態様は、第2態様において、前記評価対象QRS群が正常なQRS群であるか否かを判定する正常QRS群判定手段をさらに具備し、前記種別判別手段は、前記評価対象QRS群が前記正常なQRS群と判定されたか否かに基づいて、前記評価対象QRS群で示される期外収縮の種別を判別する。 A fourth aspect of the present invention further includes, in the second aspect, a normal QRS group determining means for determining whether or not the evaluation target QRS complex is a normal QRS group, and the type determining means is the evaluation target. QRS complex is based on whether it is determined that the normal QRS complex, to determine the type of extrasystoles represented by the evaluation object QRS complex.

本発明の第5態様は、期外収縮判別方法が、期外収縮判別装置に適用される方法であって、前記期外収縮判別装置の評価対象QRS群決定手段が、心電データから得られるR波の計測状態が正常であるときに、前記計測状態が正常であるR波を含むQRS群を評価対象となる評価対象QRS群として決定し、前記期外収縮判別装置の期外収縮候補判定手段が、前記評価対象QRS群および前記評価対象QRS群に時間的に隣り合う隣接QRS群が、過去に生起したQRS群が有する洞調律の範囲にあるか否か、ならびに前記評価対象QRS群および前記隣接QRS群が、心臓が生理的にとり得る範囲内で生起しているか否かに基づいて、前記評価対象QRS群が期外収縮候補であるか否かを判定する。 In the fifth aspect of the present invention, the extra contraction discrimination method is applied to the extra contraction discriminating device, and the evaluation target QRS group determining means of the extra contraction discriminating device is obtained from the electrocardiographic data. When the measurement state of the R wave is normal, the QRS group including the R wave whose measurement state is normal is determined as the evaluation target QRS group to be evaluated, and the extra contraction candidate determination of the extra contraction discriminating device is determined. It means the evaluation object QRS complex and the adjacent QRS complex adjacent to the evaluation object QRS complex in time is, whether it is in the range of sinus rhythm with is a QRS complex occurs in the past, as well as the evaluation object QRS complex and Based on whether or not the adjacent QRS complex occurs within the range that the heart can physiologically take, it is determined whether or not the evaluation target QRS complex is a candidate for extraconstriction.

本発明の第6態様は、第5態様において、前記期外収縮判別装置の種別判別手段が、前記期外収縮候補であると判定された評価対象QRS群で示される期外収縮の種別を判別すIn the sixth aspect of the present invention, in the fifth aspect, the type determination means of the extra systole discriminating device determines the type of extra systole indicated by the evaluation target QRS group determined to be the extra systole candidate. you.

本発明の第7態様は、第5態様において、前記期外収縮判別装置の前記期外収縮候補判定手段が、前記評価対象QRS群が所定の洞調律の範囲外、且つ前記隣接QRS群が前記評価対象QRS群に対して所定の時間内に生起している場合に、前記評価対象QRS群が前記期外収縮候補であると判定る。 In the seventh aspect of the present invention, in the fifth aspect, the extra systole candidate determination means of the extra systole discriminating device is such that the evaluation target QRS complex is outside the predetermined sinus rhythm range and the adjacent QRS complex is said. If you are occurring within a predetermined time with respect to the evaluation target QRS complex, it determined that the evaluation object QRS complex is the extrasystole candidates.

本発明の第8態様は、第6態様において、前記期外収縮判別装置の正常QRS群判定手段が、前記評価対象QRS群が正常なQRS群であるか否かを判定前記期外収縮判別装置の前記種別判別手段が、前記評価対象QRS群が前記正常なQRS群と判定されたか否かに基づいて、前記評価対象QRS群で示される期外収縮の種別を判別する。 An eighth aspect of the present invention, in the sixth embodiment, the normal QRS complex determination means of the extrasystole discriminating device, said evaluation object QRS complex is determined whether a normal QRS complex, the extrasystole the type discrimination means discriminating device, based on whether the evaluation object QRS complex is determined to the normal QRS complex, to determine the type of extrasystoles represented by the evaluation object QRS complex.

本発明の第9態様は、第5態様乃至第8態様いずれか1態様に記載の期外収縮判別方法を実行させるためのプログラムである。 Ninth aspect of the present invention is a program for executing the extrasystole determination method according to any one aspect fifth aspect to the eighth aspect.

要するにこの発明によれば、計測異常状態と、正常計測状態とを判別した上で、期外収縮を判別することできる期外収縮判別装置、期外収縮判別方法及びプログラムを提供することができる。 In short, according to the present invention, it is possible to provide an extra systole discriminating device, an extra systole discriminating method and a program capable of discriminating an extra systole after discriminating between a measurement abnormal state and a normal measurement state. ..

本発明の実施形態に係る期外収縮判別システムの構成を示す図である。It is a figure which shows the structure of the extra systole determination system which concerns on embodiment of this invention. 本発明の実施形態に係る期外収縮判別システム10の動作について説明するためのフローチャートである。It is a flowchart for demonstrating the operation of the extra systole determination system 10 which concerns on embodiment of this invention. R波抽出部21にて抽出された2つのR波の評価の状態と、評価値との関係を示す図である。It is a figure which shows the relationship between the evaluation state of two R waves extracted by the R wave extraction unit 21 and the evaluation value. 計測状態評価部22の瞬時心拍再計算の一例を示す図である。It is a figure which shows an example of the instantaneous heart rate recalculation of the measurement state evaluation unit 22. R波及びRRIの関係を示す図である。It is a figure which shows the relationship between R wave and RRI. 期外収縮の一例を示す図である。It is a figure which shows an example of an extra systole. 上室性期外収縮で見られるQRS群を示す図である。It is a figure which shows the QRS complex seen in the supraventricular extrasystole. 心室性期外収縮で見られるQRS群を示す図である。It is a figure which shows the QRS complex seen in the ventricular extrasystole. アーチファクトやノイズを有する心電データを示す図である。It is a figure which shows the electrocardiographic data which has an artifact and noise.

以下、図面を参照して、本発明の実施形態に係る期外収縮判別装置について説明する。 Hereinafter, the extra systole discriminating device according to the embodiment of the present invention will be described with reference to the drawings.

本実施形態の期外収縮判別装置は、心電図の計測状態を判別した上で、アーチファクトなどの計測異常が生じていない状況で検出したQRS群を対象としてQRS群の生起時間の妥当性を評価することで、ウェアラブル心電計による期外収縮判別を実現することを特徴とする。なお、心室性期外収縮と上室性期外収縮の判別を行う際には、QRS群の生起時間に加えて形状の妥当性も評価対象とする。 The extra systole discriminating device of the present embodiment discriminates the measurement state of the electrocardiogram, and then evaluates the validity of the occurrence time of the QRS complex for the QRS complex detected in a situation where there is no measurement abnormality such as an artifact. This is characterized by realizing extrasystole discrimination by a wearable electrocardiograph. When discriminating between ventricular extrasystoles and supraventricular extrasystoles, the validity of the shape is also evaluated in addition to the occurrence time of the QRS complex.

図1は、本発明の実施形態に係る期外収縮判別システムの構成を示す図である。同図に示すように、期外収縮判別システム10は、心電計測部11と期外収縮判別装置12とを具備する。 FIG. 1 is a diagram showing a configuration of an extra systole determination system according to an embodiment of the present invention. As shown in the figure, the extra systole determination system 10 includes an electrocardiographic measurement unit 11 and an extra systole determination device 12.

一例として、期外収縮判別システム10は、心電計測部11を被験者(ユーザ)に装着可能なウェアラブルデバイスとし、期外収縮判別装置12をスマートフォン、タブレット型端末、パーソナルコンピュータ(PC)などのコンピュータデバイスとしたシステムにより実現される。例えば、コンピュータデバイスは、CPU(Central Processing Unit)などのプロセッサと、プロセッサに接続されるメモリと、心電計測部11と(例えば無線で)通信するための通信インタフェースと、を備える。 As an example, in the extra systole determination system 10, the electrocardiographic measurement unit 11 is a wearable device that can be worn by a subject (user), and the extra systole determination device 12 is a computer such as a smartphone, a tablet terminal, or a personal computer (PC). It is realized by the system as a device. For example, a computer device includes a processor such as a CPU (Central Processing Unit), a memory connected to the processor, and a communication interface for communicating (for example, wirelessly) with the electrocardiographic measuring unit 11.

なお、期外収縮判別システム10の実現形態は、この例に限定されるものではない。例えば、期外収縮判別システム10は1つのデバイスとして実現されてもよい。また、心電計測部11は期外収縮判別システム10の外部に設けられてもよい。言い換えると、期外収縮判別システム10は、心電計測部11に相当する外部の心電計測装置から被験者の心電を計測した結果を取得してもよい。 The embodiment of the extra systole determination system 10 is not limited to this example. For example, the extra systole determination system 10 may be realized as one device. Further, the electrocardiographic measurement unit 11 may be provided outside the extra systole determination system 10. In other words, the extra systole determination system 10 may acquire the result of measuring the electrocardiogram of the subject from an external electrocardiographic measuring device corresponding to the electrocardiographic measuring unit 11.

心電計測部11は、被験者の心電を計測し、計測結果をR波抽出部21に送る。心電は、循環器系の生体信号であり、例えば、心室の収縮と同期した周期的な信号を含む。心電計測部11は、少なくとも2極の電極によって心電の計測を行う。計測結果は、心電図におけるR波相当の心電を抽出可能な時系列データを含む。例えば、計測結果は心電図の時系列データを含む。心電計測部11は、R波相当の心電を計測することができればよく、その実現形態は問わない。例えば、心電計測部11はホルター心電計からなる。 The electrocardiographic measurement unit 11 measures the electrocardiogram of the subject and sends the measurement result to the R wave extraction unit 21. The electrocardiogram is a biological signal of the circulatory system, including, for example, a periodic signal synchronized with the contraction of the ventricles. The electrocardiographic measurement unit 11 measures the electrocardiogram with at least two electrodes. The measurement result includes time series data capable of extracting an electrocardiogram corresponding to an R wave in an electrocardiogram. For example, the measurement result includes time series data of the electrocardiogram. The electrocardiographic measurement unit 11 only needs to be able to measure the electrocardiogram equivalent to the R wave, and the embodiment thereof does not matter. For example, the electrocardiographic measurement unit 11 includes a Holter electrocardiograph.

期外収縮判別装置12は、R波抽出部21、計測状態評価部22、QRS群形状評価部23、QRS群生起時間評価部24及び期外収縮判定部25を具備する。なお、心電計測部11、R波抽出部21、計測状態評価部22の機能ブロックについては、既存の別の技術を使用しても良い。 The extra systole determination device 12 includes an R wave extraction unit 21, a measurement state evaluation unit 22, a QRS complex shape evaluation unit 23, a QRS complex occurrence time evaluation unit 24, and an extra systole determination unit 25. As for the functional blocks of the electrocardiographic measurement unit 11, the R wave extraction unit 21, and the measurement state evaluation unit 22, another existing technique may be used.

これらR波抽出部21、計測状態評価部22、QRS群形状評価部23、QRS群生起時間評価部24及び期外収縮判定部25の機能は、例えば、プロセッサがメモリに格納されているプログラムを読み出して実行することにより実現される。なお、これらの機能の一部または全部は、特定用途向け集積回路(ASIC)などの回路によって実現されてもよい。 The functions of the R wave extraction unit 21, the measurement state evaluation unit 22, the QRS complex shape evaluation unit 23, the QRS complex occurrence time evaluation unit 24, and the extra systole determination unit 25 are, for example, a program in which the processor is stored in the memory. It is realized by reading and executing. Note that some or all of these functions may be realized by a circuit such as an application specific integrated circuit (ASIC).

R波抽出部21は、心電計測部11によって計測された心電の時系列データを解析し、R波を抽出する。実施形態では、具体的なR波の抽出方法は問わない。後続処理で必要がある場合については、抽出したR波に関連する情報を、R波関連情報記録部(図示せず)に記録しても良い。R波関連情報記録部は、R波抽出部21で抽出したR波に関する情報を記録する。実施形態では、具体的な記録方法については特に指定しない。 The R wave extraction unit 21 analyzes the time series data of the electrocardiogram measured by the electrocardiogram measurement unit 11 and extracts the R wave. In the embodiment, the specific method for extracting the R wave does not matter. When it is necessary for the subsequent processing, the information related to the extracted R wave may be recorded in the R wave related information recording unit (not shown). The R wave related information recording unit records information related to the R wave extracted by the R wave extraction unit 21. In the embodiment, no specific recording method is specified.

計測状態評価部22は、心電計測部11、R波関連情報記録部、瞬時心拍情報記録部(図示せず)などの情報を基に、心電図の計測状態を評価する。ここで、瞬時心拍情報記録部は、瞬時心拍を記録する。具体的な記録形式については特に指定しないが、例えば、瞬時心拍の行列や、瞬時心拍を構成する1つ目のR波の時刻情報と瞬時心拍の二つから構成されるデータ行列が考えられる。なお、瞬時心拍情報記録部は実施形態において必須の機能ではない。計測状態評価部22は、アーチファクトを含まない正常に計測できている箇所と、アーチファクトをはじめとする計測異常が判別できる手法であればよく、その実現手法については実施形態では具体的に指定しない。 The measurement state evaluation unit 22 evaluates the measurement state of the electrocardiogram based on the information of the electrocardiogram measurement unit 11, the R wave-related information recording unit, the instantaneous heartbeat information recording unit (not shown), and the like. Here, the instantaneous heartbeat information recording unit records the instantaneous heartbeat. Although the specific recording format is not particularly specified, for example, a matrix of instantaneous heartbeats and a data matrix composed of the time information of the first R wave constituting the instantaneous heartbeat and the instantaneous heartbeat can be considered. The instantaneous heartbeat information recording unit is not an essential function in the embodiment. The measurement state evaluation unit 22 may be any method as long as it can discriminate between a portion that does not include an artifact and can be measured normally and a measurement abnormality such as an artifact, and the method for realizing the measurement is not specifically specified in the embodiment.

QRS群形状評価部23は、計測状態評価部22の計測状態の評価の結果、正常計測状態で検出されたR波のみを対象として、QRS群の形状評価を行う。具体的な処理については後述する。QRS群形状評価部23は、実施形態では必ずしも必須ではないが、後続の期外収縮判定部25において、図7に示した上室性期外収縮と、図8に示した心室性期外収縮とを判別したい場合には必須の機能となる。 The QRS complex shape evaluation unit 23 evaluates the shape of the QRS complex only for the R wave detected in the normal measurement state as a result of the evaluation of the measurement state of the measurement state evaluation unit 22. The specific processing will be described later. The QRS complex shape evaluation unit 23 is not necessarily essential in the embodiment, but in the subsequent extra systole determination unit 25, the supraventricular extra systole shown in FIG. 7 and the ventricular extra systole shown in FIG. 8 It is an indispensable function when you want to distinguish.

QRS群生起時間評価部24は、計測状態評価部22の結果、正常計測状態で検出されたR波のみを対象として、QRS群の生起時間の評価を行なう。具体的な処理については後述する。 The QRS complex occurrence time evaluation unit 24 evaluates the occurrence time of the QRS complex only for the R wave detected in the normal measurement state as a result of the measurement state evaluation unit 22. The specific processing will be described later.

期外収縮判定部25は、QRS群形状評価部23及びQRS群生起時間評価部24の情報を基に、期外収縮を判定する。具体的な処理については後述する。 The extra systole determination unit 25 determines the extra systole based on the information of the QRS complex shape evaluation unit 23 and the QRS complex occurrence time evaluation unit 24. The specific processing will be described later.

次に、本発明の実施形態に係る期外収縮判別システム10の動作について、図2のフローチャートを参照して説明する。 Next, the operation of the extra systole determination system 10 according to the embodiment of the present invention will be described with reference to the flowchart of FIG.

なお,本実施形態では,あらかじめ心電計測部11で取得した心電データを対象としており、期外収縮判別装置12が対象となる心電データをオフラインに実行する場合を例として説明するが、これ以外の手法で実現しても良い。例えば、以降で述べる処理をすべてオンラインで順次処理しても良いし、一部のみをオンラインとしてそれ以外をオフライン処理しても良いものとする。 In this embodiment, the electrocardiographic data acquired in advance by the electrocardiographic measurement unit 11 is targeted, and the case where the extra systole discriminating device 12 executes the target electrocardiographic data offline will be described as an example. It may be realized by a method other than this. For example, all the processes described below may be sequentially processed online, or only a part may be online and the others may be offline.

まず、心電計測部11は、被験者の心電を計測して、被験者の心電図のための時系列の心電図データをR波抽出部21に送る(S1)。R波抽出部21は、心電計測部11にて計測された時系列の心電データからR波を抽出する(S2)。 First, the electrocardiographic measurement unit 11 measures the subject's electrocardiogram and sends time-series electrocardiogram data for the subject's electrocardiogram to the R wave extraction unit 21 (S1). The R wave extraction unit 21 extracts an R wave from the time-series electrocardiographic data measured by the electrocardiographic measurement unit 11 (S2).

計測状態評価部22は、対象となる心電図の心電データの計測状態を評価する。実施形態では、評価基準(参考文献[i],[ii]参照)に基づき、抽出されたR波がアーチファクトであるかどうかを判別し、アーチファクトでないと判別されたR波を正常計測状態とみなす。計測状態評価部22には、必要に応じて、心電計測部11からの心電データが入力されても良い。実施形態では、例えば、R波抽出部21で検出したR波のうち、電圧値が4.0[mV]以上のものを計測異常のアーチファクトとみなす。 The measurement state evaluation unit 22 evaluates the measurement state of the electrocardiographic data of the target electrocardiogram. In the embodiment, it is determined whether or not the extracted R wave is an artifact based on the evaluation criteria (see References [i] and [ii]), and the R wave determined not to be an artifact is regarded as a normal measurement state. .. If necessary, the electrocardiographic data from the electrocardiographic measurement unit 11 may be input to the measurement state evaluation unit 22. In the embodiment, for example, among the R waves detected by the R wave extraction unit 21, those having a voltage value of 4.0 [mV] or more are regarded as measurement abnormality artifacts.

計測状態評価部22は、各R波に付与された計測状態に基づき、隣接する二つのR波から構成される瞬時心拍を評価する。正常計測状態、アーチファクトの二種を考慮する場合、瞬時心拍を構成するR波の組み合わせは「正常−正常」「正常−アーチファクト」「アーチファクト−正常」「アーチファクト−アーチファクト」のいずれかとなる。実施形態では、「正常−正常」のQRS群をQRS群形状評価部23の評価対象として送出する(S3)。 The measurement state evaluation unit 22 evaluates an instantaneous heartbeat composed of two adjacent R waves based on the measurement state applied to each R wave. When considering the two types of normal measurement state and artifact, the combination of R waves constituting the instantaneous heartbeat is one of "normal-normal", "normal-artifact", "artifact-normal", and "artifact-artifact". In the embodiment, a “normal-normal” QRS complex is sent out as an evaluation target of the QRS complex shape evaluation unit 23 (S3).

図3は、R波抽出部21にて抽出された2つのR波の評価の状態と、評価値との関係を示す図である。同図に示すように、R波抽出部21にて抽出されたR波が2つとも正常計測状態であると判断される場合には、計測状態評価部22における評価値は、「1」となる。R波抽出部21にて抽出されたR波が片方は正常計測状態、他方はアーチファクトであると判断される場合には、「評価値」は、「0.5」となる。R波抽出部21にて抽出されたR波が2つともアーチファクトである場合には、「評価値」は「0」となる。 FIG. 3 is a diagram showing the relationship between the evaluation state of the two R waves extracted by the R wave extraction unit 21 and the evaluation value. As shown in the figure, when it is determined that both R waves extracted by the R wave extraction unit 21 are in the normal measurement state, the evaluation value in the measurement state evaluation unit 22 is "1". Become. When it is determined that one of the R waves extracted by the R wave extraction unit 21 is in a normal measurement state and the other is an artifact, the "evaluation value" is "0.5". When both R waves extracted by the R wave extraction unit 21 are artifacts, the "evaluation value" is "0".

なお,この評価はあくまでも一例であり、アーチファクトを最終的に評価対象から除外できるのであれば「正常−アーチファクト」や「アーチファクト−正常」を対象に含めても良い。 This evaluation is just an example, and if the artifact can be finally excluded from the evaluation target, "normal-artifact" or "artifact-normal" may be included in the target.

また、計測状態評価部22は、評価対象となるQRS群に対して、任意処理として、瞬時心拍の再計算処理を行なっても良い。 Further, the measurement state evaluation unit 22 may perform an instantaneous heartbeat recalculation process as an optional process for the QRS group to be evaluated.

具体的には、計測状態評価部22は、計測状態評価部22における評価の結果に基づいて瞬時心拍の再計算を行う。図4は本発明の実施形態における計測状態評価部22の瞬時心拍再計算の一例を示す図である。 Specifically, the measurement state evaluation unit 22 recalculates the instantaneous heartbeat based on the evaluation result in the measurement state evaluation unit 22. FIG. 4 is a diagram showing an example of instantaneous heartbeat recalculation of the measurement state evaluation unit 22 according to the embodiment of the present invention.

また、瞬時心拍再計算では、表1で示す#2、#3および#4のいずれかに該当すると評価された瞬時心拍を構成する、隣接する2つのR波における、アーチファクトとして判別されたR波を棄却し、残りの正常計測状態と判別されたR波のみを用いて、隣接する2つのR波である瞬時心拍を構成する。 Further, in the instantaneous heartbeat recalculation, the R wave determined as an artifact in the two adjacent R waves constituting the instantaneous heartbeat evaluated to correspond to any of # 2, # 3 and # 4 shown in Table 1. Is rejected, and only the remaining R waves determined to be in the normal measurement state are used to construct an instantaneous heartbeat which is two adjacent R waves.

図2に示した例では、再計算前のR波は、時系列に沿って、R波番号「1」、「2」の「R(正常計測状態)」、R波番号「3」の「A(アーチファクト)」、R波番号「4」の「R」、R波番号「5」、「6」、「7」の「A」、R波番号「8」、「9」の「R」と判別されたR波である。
これに対し、瞬時心拍再計算では、R波番号「3」、「5」、「6」、「7」の「A」と判別されたR波を棄却し、残りのR波番号「1」、「2」、「4」、「8」、「9」の「R」と判別されたR波を用いて、1つ目の瞬時心拍(隣接する、R波番号「1」、「2」に対応する2つのR波で構成)、2つ目の瞬時心拍(隣接する、R波番号「2」、「4」に対応する2つのR波で構成)、3つ目の瞬時心拍(隣接する、R波番号「4」、「8」に対応する2つのR波で構成)、4つ目の瞬時心拍(隣接する、R波番号「8」、「9」に対応する2つのR波で構成)を構成する。これら再計算後の、瞬時心拍評価部25による、瞬時心拍の計測状態の評価は、表1に示す「#1(2つとも正常計測状態)」のみとなる。
In the example shown in FIG. 2, the R wave before recalculation has the R wave numbers “1” and “2” “R (normal measurement state)” and the R wave number “3” “3” in chronological order. "A (artifact)", "R" of R wave number "4", "R" of R wave number "5", "6", "7", "R" of R wave number "8", "9" It is an R wave determined to be.
On the other hand, in the instantaneous heart rate recalculation, the R wave determined to be "A" of the R wave numbers "3", "5", "6", and "7" is rejected, and the remaining R wave number "1". , "2", "4", "8", "9" using the R wave determined to be "R", the first instantaneous heartbeat (adjacent, R wave number "1", "2" (Composed of two R waves corresponding to), second instantaneous heartbeat (adjacent, composed of two R waves corresponding to R wave numbers "2" and "4"), and third instantaneous heartbeat (adjacent) (Composed of two R waves corresponding to R wave numbers "4" and "8"), and a fourth instantaneous heartbeat (adjacent, two R waves corresponding to R wave numbers "8" and "9") Consists of). After these recalculations, the instantaneous heartbeat evaluation unit 25 evaluates the instantaneous heartbeat measurement state only in "# 1 (both are normal measurement states)" shown in Table 1.

QRS群形状評価部23は、計測状態評価部22から送信されたQRS群の形状の妥当性を評価する(S4)。具体的には,図7に示した正常なQRS群と,図8に示す図7とは異なる異常なQRS群を判別できれば良い。 The QRS complex shape evaluation unit 23 evaluates the validity of the shape of the QRS complex transmitted from the measurement state evaluation unit 22 (S4). Specifically, it suffices if the normal QRS complex shown in FIG. 7 and the abnormal QRS group different from FIG. 7 shown in FIG. 8 can be discriminated.

実施形態では、「R波抽出部」で検出したR波におけるQ波およびS波を算出し、QRS群の持続時間が正常値の範囲内に収まるものを「正常なQRS群」、正常な範囲を超過したものを「異常なQRS群」とみなす。なお、この評価方法はあくまでも一例であり、図7及び図8に示すQRS群が判別できれば別の手法でも良い。
QRS群生起時間評価部24は、QRS群の生起時間の妥当性を評価する(S5)。実施形態では、評価対象QRS群に時間的に隣り合う隣接QRS群に基づいて、評価対象QRS群が期外収縮候補であるかを判定する。具体的には、評価対象となるQRS群と、評価対象となるQRS群に時間的に隣り合う前後のQRS群が、過去に生起したQRS群が持っている洞調律の範囲にあるか、ならびに、評価対象となるQRS群と、その前後のQRS群が、心臓が生理的にとり得る範囲内で生起しているかを評価する。これら二つの評価の結果、洞調律の範囲からはずれ、かつ、心臓が生理的にとり得る範囲内で生起したQRS群を「期外収縮候補」と判定する。
In the embodiment, the Q wave and the S wave in the R wave detected by the "R wave extraction unit" are calculated, and the one in which the duration of the QRS group falls within the normal value range is the "normal QRS group" and the normal range. Those exceeding the above are regarded as "abnormal QRS complex". Note that this evaluation method is merely an example, and another method may be used as long as the QRS complex shown in FIGS. 7 and 8 can be discriminated.
The QRS complex occurrence time evaluation unit 24 evaluates the validity of the occurrence time of the QRS complex (S5). In the embodiment, it is determined whether the evaluation target QRS complex is an extra systole candidate based on the adjacent QRS complex temporally adjacent to the evaluation target QRS complex. Specifically, is the QRS complex to be evaluated and the QRS complex before and after the QRS complex to be evaluated temporally adjacent to each other within the sinus rhythm range of the QRS complex that occurred in the past? , Evaluate whether the QRS complex to be evaluated and the QRS complex before and after it occur within the range that the heart can physiologically take. As a result of these two evaluations, the QRS complex that is out of the range of sinus rhythm and occurs within the range that the heart can physiologically take is judged as an "extra systole candidate".

実施形態では、これらの基準については具体的には規定しないが、例えば、平均±n×標準偏差の範囲を洞調律とし、その範囲内におさまらない値を抜き出した上で、平均−n×標準偏差以下で生起したQRS群を対象とし、最大心拍数に対応する250[msec]以上の間隔で生起したものを「期外収縮候補」と判定することなどが考えられる。ここで、評価対象となるRRIの変動が、平均+n×標準偏差を超過している場合については、評価対象となるRRIを、「期外収縮候補」ではなく、計測異常RRIと判定しても良い。 In the embodiment, these criteria are not specifically specified, but for example, the range of mean ± n × standard deviation is set as sinus rhythm, and values that do not fall within that range are extracted, and then the mean −n × standard. It is conceivable that the QRS complex that occurs below the deviation is targeted, and those that occur at intervals of 250 [msec] or more corresponding to the maximum heart rate are judged as “extra systole candidates”. Here, when the fluctuation of the RRI to be evaluated exceeds the average + n × standard deviation, even if the RRI to be evaluated is determined not as an “extra systole candidate” but as a measurement abnormality RRI. good.

期外収縮判定部25は、QRS群形状評価部23及びQRS群生起時間評価部24の結果に基づいて、期外収縮を評価する(S6)。QRS群生起時間評価部24のみを用いる場合は、S5で「期外収縮候補」と判別したものを「期外収縮」と判定する。 The extra systole determination unit 25 evaluates the extra systole based on the results of the QRS complex shape evaluation unit 23 and the QRS complex occurrence time evaluation unit 24 (S6). When only the QRS complex occurrence time evaluation unit 24 is used, the one determined as "extra systole candidate" in S5 is determined as "extra systole".

QRS群形状評価部23とQRS群生起時間評価部24の二つの情報を用いる場合は、S5で「期外収縮候補」と判定したQRS群の、S4の判定結果を参照する。S5で「期外収縮候補」かつS4で「正常なQRS群」であるものを「上室性期外収縮」、S5で「期外収縮候補」かつS4で「異常なQRS群」であるものを「心室性期外収縮」と判定する。 When using the two pieces of information of the QRS complex shape evaluation unit 23 and the QRS complex occurrence time evaluation unit 24, the determination result of S4 of the QRS group determined as "extra systole candidate" in S5 is referred to. "Extrasystole candidate" in S5 and "normal QRS complex" in S4 is "supraventricular extrasystole", "extrasystole candidate" in S5 and "abnormal QRS complex" in S4 Is determined to be "ventricular extrasystole".

なお、「上室性期外収縮」の判定については、心電計測部11がP波を測定できる実現形態であれば、当該QRS群に対応するP波の有無でさらに詳細な判別を行っても良い。例えば、「上室性期外収縮」と判定されたものにP波があれば「心房性期外収縮」、P波がなければ「房室接合部性期外収縮」と判定しても良い。 Regarding the determination of "supraventricular extrasystole", if the electrocardiographic measurement unit 11 can measure the P wave, a more detailed determination is made based on the presence or absence of the P wave corresponding to the QRS complex. Is also good. For example, if there is a P wave in what is determined to be "supraventricular extrasystole", it may be determined to be "atrial extrasystole", and if there is no P wave, it may be determined to be "atrial junction extrasystole". ..

従って、本実施形態の期外収縮判別装置によれば、計測状態評価部22によって、計測異常R波を含むRRIを評価対象から除外することで、ウェアラブル心電計で取得した心電図を対象とした異常評価を可能とすることができる。 Therefore, according to the extra systole discriminating device of the present embodiment, the measurement state evaluation unit 22 excludes the RRI including the measurement abnormality R wave from the evaluation target, so that the electrocardiogram acquired by the wearable electrocardiograph is targeted. Abnormality evaluation can be made possible.

また、QRS群生起時間評価部24の結果に基づいて、期外収縮を判定することで、筋電アーチファクトなど電位の小さいアーチファクトと期外収縮の判別が可能となる。 Further, by determining the extra systole based on the result of the QRS complex occurrence time evaluation unit 24, it is possible to discriminate between an artifact having a small potential such as an EMG artifact and an extra systole.

さらに、QRS群生起時間評価部24に加え、QRS群形状評価部23でQRS群の形状を評価することで、上室性期外収縮と心室性期外収縮の判別が可能となる。 Further, by evaluating the shape of the QRS complex by the QRS complex shape evaluation unit 23 in addition to the QRS complex occurrence time evaluation unit 24, it is possible to discriminate between the supraventricular extrasystole and the ventricular extrasystole.

本発明は、上記実施形態そのままに限定されるものではなく、実施段階ではその要旨を逸脱しない範囲で構成要素を変形して具体化できる。また、上記実施形態に開示されている複数の構成要素の適宜な組み合せにより種々の発明を形成できる。例えば、実施形態に示される全構成要素から幾つかの構成要素を削除してもよい。さらに、異なる実施形態に亘る構成要素を適宜組み合せてもよい。
参考文献
i) 奥出潤、これならわかる!かんたんポイント心電図 第2版、医学書院、2011
ii) 渡辺重行ら、心電図の読み方パーフェクトマニュアル、羊土社、2006
iii) 井上博、循環器疾患と自律神経機能 第2版、医学書院、2001
iv) 日本光電、雑音混入のメカニズムと対策:きれいな心電図を記録するポイント 〜ホルター心電図編〜(2017年3月23日確認)
http://www.nihonkohden.co.jp/iryo/point/holter/mechanism.html
v) 国立循環器病研究センター 循環器情報サービス、怖い不整脈と怖くない不整脈、
(2017年3月23日確認)
http://www.ncvc.go.jp/cvdinfo/pamphlet/heart/pamph06.html
The present invention is not limited to the above-described embodiment as it is, and at the implementation stage, the components can be modified and embodied without departing from the gist thereof. In addition, various inventions can be formed by an appropriate combination of a plurality of components disclosed in the above-described embodiment. For example, some components may be removed from all the components shown in the embodiments. In addition, components from different embodiments may be combined as appropriate.
References i) Jun Okude, you know this! Easy Point ECG 2nd Edition, Igaku-Shoin, 2011
ii) Shigeyuki Watanabe et al., How to read an electrocardiogram Perfect Manual, Yodosha, 2006
iii) Hiroshi Inoue, Cardiovascular Disease and Autonomic Nervous Function 2nd Edition, Igaku-Shoin, 2001
iv) Nihon Kohden, Mechanism and Countermeasures for Noise Mixing: Points for Recording a Clean ECG-Holter ECG- (Confirmed on March 23, 2017)
http: // www. nihon kohden. co. jp / iryo / point / halter / medical. html
v) National Cardiovascular Research Center Cardiovascular Information Service, Scary Arrhythmia and Non-Scary Arrhythmia,
(Confirmed on March 23, 2017)
http: // www. ncvc. go. jp / cvdinfo / pamphlet / heart / pamphlet 06. html

10…期外収縮判別システム、11…心電計測部、12…期外収縮判別装置、21…R波抽出部、22…計測状態評価部、23…QRS群形状評価部、24…QRS群生起時間評価部、25…期外収縮判定部。 10 ... Extra systole determination system, 11 ... Electrocardiographic measurement unit, 12 ... Extra systole determination device, 21 ... R wave extraction unit, 22 ... Measurement state evaluation unit, 23 ... QRS group shape evaluation unit, 24 ... QRS complex occurrence Time evaluation unit, 25 ... Extra systole determination unit.

Claims (9)

心電データから得られるR波の計測状態が正常であるときに、前記計測状態が正常であるR波を含むQRS群を評価対象となる評価対象QRS群として決定する評価対象QRS群決定手段と、
前記評価対象QRS群および前記評価対象QRS群に時間的に隣り合う隣接QRS群が、過去に生起したQRS群が有する洞調律の範囲にあるか否か、ならびに前記評価対象QRS群および前記隣接QRS群が、心臓が生理的にとり得る範囲内で生起しているか否かに基づいて、前記評価対象QRS群が期外収縮候補であるか否かを判定する期外収縮候補判定手段と、
を具備する期外収縮判別装置。
When the measurement state of the R wave obtained from the electrocardiographic data is normal, the evaluation target QRS group determining means for determining the QRS group including the R wave whose measurement state is normal as the evaluation target QRS group to be evaluated. ,
The evaluation object QRS complex and the adjacent QRS complex adjacent to the evaluation object QRS complex in time is, whether it is in the range of sinus rhythm with is a QRS complex occurs in the past, as well as the evaluation object QRS group and the adjacent QRS An extra systole candidate determination means for determining whether or not the evaluation target QRS complex is an extra systole candidate based on whether or not the group occurs within the range that the heart can physiologically take .
An extra systole discriminating device comprising.
前記期外収縮候補であると判定された評価対象QRS群で示される期外収縮の種別を判別する種別判別手段をさらに具備する、
請求項1記載の期外収縮判別装置。
Further provided with a type discriminating means for discriminating the type of extra systole indicated by the evaluation target QRS group determined to be the extra systole candidate.
The extra systole discriminating device according to claim 1.
前記期外収縮候補判定手段は、
前記評価対象QRS群が所定の洞調律の範囲外、且つ前記隣接QRS群が前記評価対象QRS群に対して所定の時間内に生起している場合に、前記評価対象QRS群が前記期外収縮候補であると判定する、
請求項1記載の期外収縮判別装置。
The extra systole candidate determination means
When the evaluation target QRS complex is out of the predetermined sinus rhythm range and the adjacent QRS complex occurs within a predetermined time with respect to the evaluation target QRS complex, the evaluation target QRS complex causes the extra systole. Judge as a candidate,
The extra systole discriminating device according to claim 1.
前記評価対象QRS群が正常なQRS群であるか否かを判定する正常QRS群判定手段をさらに具備し、
前記種別判別手段は、
前記評価対象QRS群が前記正常なQRS群と判定されたか否かに基づいて、前記評価対象QRS群で示される期外収縮の種別を判別する、
請求項2記載の期外収縮判別装置。
Further provided with a normal QRS group determination means for determining whether or not the evaluation target QRS group is a normal QRS group.
The type determination means
The type of extra systole indicated by the evaluation target QRS complex is determined based on whether or not the evaluation target QRS complex is determined to be the normal QRS group.
The extra systole discriminating device according to claim 2.
期外収縮判別装置に適用される方法であって、
前記期外収縮判別装置の評価対象QRS群決定手段が、
心電データから得られるR波の計測状態が正常であるときに、前記計測状態が正常であるR波を含むQRS群を評価対象となる評価対象QRS群として決定し、
前記期外収縮判別装置の期外収縮候補判定手段が、
前記評価対象QRS群および前記評価対象QRS群に時間的に隣り合う隣接QRS群が、過去に生起したQRS群が有する洞調律の範囲にあるか否か、ならびに前記評価対象QRS群および前記隣接QRS群が、心臓が生理的にとり得る範囲内で生起しているか否かに基づいて、前記評価対象QRS群が期外収縮候補であるか否かを判定する、
期外収縮判別方法。
This method is applied to extra systole discriminators.
The evaluation target QRS group determination means of the extra systole discriminating device is
When the measurement state of the R wave obtained from the electrocardiographic data is normal, the QRS group including the R wave whose measurement state is normal is determined as the evaluation target QRS group to be evaluated.
The extra systole candidate determination means of the extra systole determination device
The evaluation object QRS complex and the adjacent QRS complex adjacent to the evaluation object QRS complex in time is, whether it is in the range of sinus rhythm with is a QRS complex occurs in the past, as well as the evaluation object QRS group and the adjacent QRS It is determined whether or not the QRS complex to be evaluated is a candidate for extrasystole based on whether or not the group occurs within the range that the heart can physiologically take .
Extra systole determination method.
前記期外収縮判別装置の種別判別手段が、
前記期外収縮候補であると判定された評価対象QRS群で示される期外収縮の種別を判別する、
請求項5記載の期外収縮判別方法。
The type discrimination means of the extra systole discriminating device is
The type of extra systole indicated by the evaluation target QRS complex determined to be the extra systole candidate is determined.
The extrasystole determination method according to claim 5.
前記期外収縮判別装置の前記期外収縮候補判定手段が、
前記評価対象QRS群が所定の洞調律の範囲外、且つ前記隣接QRS群が前記評価対象QRS群に対して所定の時間内に生起している場合に、前記評価対象QRS群が前記期外収縮候補であると判定する、
請求項5記載の期外収縮判別方法。
The extra systole candidate determination means of the extra systole determination device
When the evaluation target QRS complex is out of the predetermined sinus rhythm range and the adjacent QRS complex occurs within a predetermined time with respect to the evaluation target QRS complex, the evaluation target QRS complex causes the extra systole. Judge as a candidate,
The extrasystole determination method according to claim 5.
前記期外収縮判別装置の正常QRS群判定手段が、
前記評価対象QRS群が正常なQRS群であるか否かを判定し、
前記期外収縮判別装置の前記種別判別手段が、
前記評価対象QRS群が前記正常なQRS群と判定されたか否かに基づいて、前記評価対象QRS群で示される期外収縮の種別を判別する、
請求項6記載の期外収縮判別方法。
The normal QRS group determination means of the extra systole determination device
It is determined whether or not the evaluation target QRS group is a normal QRS group, and the evaluation target QRS group is determined.
The type discrimination means of the extra systole discriminating device
The type of extra systole indicated by the evaluation target QRS complex is determined based on whether or not the evaluation target QRS complex is determined to be the normal QRS group.
The extrasystole determination method according to claim 6.
コンピュータに、請求項5乃至請求項8いずれか1項に記載の期外収縮判別方法を実行させるためのプログラム。 A program for causing a computer to execute the extra systole determination method according to any one of claims 5 to 8.
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