JP6716468B2 - 肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物 - Google Patents

肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物 Download PDF

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JP6716468B2
JP6716468B2 JP2016566672A JP2016566672A JP6716468B2 JP 6716468 B2 JP6716468 B2 JP 6716468B2 JP 2016566672 A JP2016566672 A JP 2016566672A JP 2016566672 A JP2016566672 A JP 2016566672A JP 6716468 B2 JP6716468 B2 JP 6716468B2
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resveratrol
ursolic acid
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res
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トーマス ジェイ． スラガ
トーマス ジェイ． スラガ
ジェイコブ ジュンコ
ジェイコブ ジュンコ
フイユン リャン
フイユン リャン
サラ レイナ
サラ レイナ
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University of Texas System
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
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  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016566672A 2014-05-05 2015-05-05 肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物 Active JP6716468B2 (ja)

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US201461988859P 2014-05-05 2014-05-05
US61/988,859 2014-05-05
PCT/US2015/029224 WO2015171598A1 (en) 2014-05-05 2015-05-05 Methods and compositions comprising ursolic acid and/or resveratrol for treating obesity, diabetes, or cancer

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JP2020100600A Division JP2020147590A (ja) 2014-05-05 2020-06-10 肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物

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JP2017514858A JP2017514858A (ja) 2017-06-08
JP2017514858A5 JP2017514858A5 (enExample) 2018-06-14
JP6716468B2 true JP6716468B2 (ja) 2020-07-01

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JP2020100600A Pending JP2020147590A (ja) 2014-05-05 2020-06-10 肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物

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EP (1) EP3139910B1 (enExample)
JP (2) JP6716468B2 (enExample)
AU (2) AU2015256178B2 (enExample)
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WO (1) WO2015171598A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6716468B2 (ja) * 2014-05-05 2020-07-01 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物
EP3399959B1 (en) * 2015-11-13 2023-05-24 Thornalley, Paul John Composition to improve metabolic and vascular health and health span
GB201702160D0 (en) * 2017-02-09 2017-03-29 Univ Leeds Innovations Ltd Inhibitors for use in therapy
US11464795B2 (en) 2017-07-13 2022-10-11 East China University Of Science And Technology Saponin compound targeting PD-1 and application thereof
WO2019055280A1 (en) 2017-09-13 2019-03-21 Emmyon, Inc. DIETHANOLAMINE SALTS AND URSOLIC ACID MORPHOLIN
CA3238646A1 (en) * 2021-11-18 2023-05-25 Michael A. LISS Combinations of curcumin and ursolic acid and uses thereof

Family Cites Families (13)

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US20070269537A1 (en) * 2003-02-10 2007-11-22 Bioderm Research Skin Condition Improvement Including Acne, Rosacea, and Topical Wounds by Artemisia Annua Extract via Iron Siderophore Trojan Horse Delivery System
JP2006273834A (ja) * 2004-06-28 2006-10-12 Kao Corp Ａｍｐｋ活性化剤
US7772195B2 (en) 2004-07-29 2010-08-10 Board Of Trustees Of Michigan State University Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia
KR101435228B1 (ko) * 2006-07-14 2014-08-28 디에스엠 아이피 어셋츠 비.브이. 조성물, 및 염증성 질환의 치료, 병용-치료 또는 예방을 위한 이의 용도
DK2118279T3 (en) * 2007-01-16 2018-02-26 Ipintl Llc HIS UNKNOWN COMPOSITION FOR TREATMENT OF METABOLIC SYNDROME
CN101032564B (zh) * 2007-02-28 2011-03-23 天津津酒集团有限公司 调节血脂养生酒及其制备方法
WO2010095926A1 (en) 2009-02-20 2010-08-26 N.V. Nutricia Use of reveratrol for preserving cognitive functioning
SMT202000086T1 (it) * 2010-04-12 2020-03-13 Reata Pharmaceuticals Inc Bardoxolone metile per il trattamento dell'obesità
US9393221B2 (en) * 2011-07-20 2016-07-19 The General Hospital Corporation Methods and compounds for reducing intracellular lipid storage
US20140024708A1 (en) * 2012-07-17 2014-01-23 Banavara L. Mylari Ursolic acid salts for treating diabetes and obesity
US9211298B2 (en) * 2012-11-16 2015-12-15 Song Gao Compositions containing enriched natural crocin and/or crocetin, and their therapeutic or nutraceutical uses
JP6716468B2 (ja) * 2014-05-05 2020-07-01 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 肥満、糖尿病、または癌を治療するためのウルソル酸および／またはレスベラトロールを含む方法および組成物
CA3194562C (en) * 2014-07-29 2026-03-17 Shenzhen Hightide Biopharmaceutical, Ltd. Berberine-ursodeoxycholic salt, method of preparation and application therof

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US20190192537A1 (en) 2019-06-27
US20200323879A1 (en) 2020-10-15
EP3139910B1 (en) 2019-11-27
US11090311B2 (en) 2021-08-17
US20200330480A1 (en) 2020-10-22
MY181685A (en) 2020-12-31
US11166962B2 (en) 2021-11-09
US20210252016A1 (en) 2021-08-19
US20220023241A1 (en) 2022-01-27
US20220226347A1 (en) 2022-07-21
WO2015171598A1 (en) 2015-11-12
AU2015256178B2 (en) 2020-02-27
US20170056414A1 (en) 2017-03-02
AU2020203419B2 (en) 2021-05-13
US10155003B2 (en) 2018-12-18
US11684626B2 (en) 2023-06-27
AU2015256178A1 (en) 2016-11-24
US11690851B2 (en) 2023-07-04
JP2020147590A (ja) 2020-09-17
US11642354B2 (en) 2023-05-09
EP3139910A4 (en) 2017-11-29
AU2020203419A1 (en) 2020-06-11
US10583145B2 (en) 2020-03-10
EP3139910A1 (en) 2017-03-15
JP2017514858A (ja) 2017-06-08

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