JP6688748B2 - 片頭痛の治療または改善方法 - Google Patents

片頭痛の治療または改善方法 Download PDF

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Publication number
JP6688748B2
JP6688748B2 JP2016575106A JP2016575106A JP6688748B2 JP 6688748 B2 JP6688748 B2 JP 6688748B2 JP 2016575106 A JP2016575106 A JP 2016575106A JP 2016575106 A JP2016575106 A JP 2016575106A JP 6688748 B2 JP6688748 B2 JP 6688748B2
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Prior art keywords
migraine
glyx
patient
aura
compound
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Japanese (ja)
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JP2017519778A (ja
JP2017519778A5 (enExample
Inventor
ジョーゼフ アール モスカル
ジョーゼフ アール モスカル
パトリック スタントン
パトリック スタントン
Original Assignee
ノースウェスタン ユニバーシティ
ノースウェスタン ユニバーシティ
ノーレックス インコーポレイテッド
ノーレックス インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016575106A 2014-06-23 2015-06-23 片頭痛の治療または改善方法 Active JP6688748B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462015727P 2014-06-23 2014-06-23
US62/015,727 2014-06-23
US201562109386P 2015-01-29 2015-01-29
US62/109,386 2015-01-29
PCT/US2015/037177 WO2015200322A1 (en) 2014-06-23 2015-06-23 Methods of treating or ameliorating migraine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020068289A Division JP2020114863A (ja) 2014-06-23 2020-04-06 片頭痛の治療または改善方法

Publications (3)

Publication Number Publication Date
JP2017519778A JP2017519778A (ja) 2017-07-20
JP2017519778A5 JP2017519778A5 (enExample) 2018-08-02
JP6688748B2 true JP6688748B2 (ja) 2020-04-28

Family

ID=54938737

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016575106A Active JP6688748B2 (ja) 2014-06-23 2015-06-23 片頭痛の治療または改善方法
JP2020068289A Pending JP2020114863A (ja) 2014-06-23 2020-04-06 片頭痛の治療または改善方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020068289A Pending JP2020114863A (ja) 2014-06-23 2020-04-06 片頭痛の治療または改善方法

Country Status (10)

Country Link
EP (1) EP3157943A4 (enExample)
JP (2) JP6688748B2 (enExample)
KR (1) KR20170018072A (enExample)
CN (1) CN106661085A (enExample)
AU (1) AU2015280108B2 (enExample)
BR (1) BR112016030375A8 (enExample)
CA (1) CA2953170A1 (enExample)
MX (1) MX2016017388A (enExample)
RU (1) RU2721401C2 (enExample)
WO (1) WO2015200322A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210151836A (ko) * 2019-04-15 2021-12-14 페린 파마슈티칼즈, 인코포레이티드 편두통의 치료

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995006468A1 (en) * 1993-09-01 1995-03-09 Smithkline Beecham Corporation Method for treating migraine headaches
US6884910B2 (en) * 2000-08-25 2005-04-26 Research Corporation Technologies, Inc. Uses for amino acid anticonvulsants
US20040053835A1 (en) * 2000-11-17 2004-03-18 Sophia Kossida Regulation of human nmda receptor
ZA200506715B (en) * 2003-03-06 2007-05-30 Botulinum Toxin Res Ass Inc Treatment of sinusitis related chronic facial pain and headache with botulinum toxin
AU2009274876C1 (en) * 2008-07-23 2016-08-18 Kyowa Kirin Co., Ltd. Therapeutic agent for migraine
WO2011003064A2 (en) * 2009-07-02 2011-01-06 Naurex, Inc. Methods of treating neuropathic pain
PT2485751E (pt) * 2009-10-05 2014-09-01 Univ Northwestern Glyx-13 para uso num método para tratar depressão refratária
US8951968B2 (en) * 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
SG10201501050RA (en) * 2010-02-11 2015-04-29 Univ Northwestern Secondary Structure Stabilized NMDA Receptor Modulators And Uses Thereof
US20140107037A1 (en) * 2011-04-27 2014-04-17 Northwestern University Methods of treating alzheimer's disease, huntington's disease, autism, or other disorders
AU2013329000A1 (en) * 2012-10-12 2015-04-30 Northwestern University Methods of identifying compounds for treating depression and other related diseases

Also Published As

Publication number Publication date
JP2020114863A (ja) 2020-07-30
CN106661085A (zh) 2017-05-10
AU2015280108B2 (en) 2019-11-28
MX2016017388A (es) 2018-02-19
EP3157943A1 (en) 2017-04-26
RU2017101410A3 (enExample) 2019-01-21
BR112016030375A2 (pt) 2017-08-15
JP2017519778A (ja) 2017-07-20
RU2721401C2 (ru) 2020-05-19
AU2015280108A1 (en) 2017-01-19
CA2953170A1 (en) 2015-12-30
BR112016030375A8 (pt) 2021-07-13
WO2015200322A1 (en) 2015-12-30
RU2017101410A (ru) 2018-07-24
KR20170018072A (ko) 2017-02-15
EP3157943A4 (en) 2018-01-24

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