JP6662699B2 - Medical image processing equipment - Google Patents

Description

  Embodiments of the present invention relate to a medical image processing apparatus.

  A DIP (Digital Image Processing) method is known as one of the measurement methods for bone mineral quantification. In the DIP method, a subject including a second metacarpal bone of the left hand to be measured is arranged, and an aluminum standard member (hereinafter, referred to as an aluminum standard member), which is a substantially rectangular standard material, does not overlap with the subject. To the right of the subject. Here, the aluminum standard member is formed so that the thickness changes continuously or stepwise between the thinnest portion at one end and the thickest portion at the other end, and the thickness changes continuously. The member is called an aluminum slope, and the member whose thickness changes stepwise is called an aluminum step. In such an aluminum standard member, the thinnest portion is located on the back side (tip side of the finger) as viewed from the subject, and the thickest portion is located on the front side (wrist side).

  Subsequently, in the DIP method, the subject and the aluminum standard member are simultaneously photographed with the X-ray aperture adjusted to include the aluminum standard member around the region of interest relating to the left metacarpal bone of the subject. To obtain an X-ray image. Thereafter, an image of the second metacarpal, which is the region of interest, is extracted from the X-ray image, and the density of the central portion of the second metacarpal within a range of 10% of the bone length, the density of the aluminum standard member, Based on the above, the value of the bone mineral quantification is measured (estimated).

  However, in the above-described DIP method, since it is necessary to image an aluminum standard member longer than the second metacarpal bone in the region of interest together with the subject, there is a concern that unnecessary exposure may occur. For example, when the X-ray aperture is adjusted so as to include the aluminum standard member centering on the second metacarpal bone of the left hand, a square area (the area of the entire palm of the left hand of the subject) is set to the length of the aluminum standard member. ) Becomes an exposure area, and there is a concern that unnecessary exposure may occur.

  On the other hand, from the viewpoint of eliminating this kind of unnecessary exposure, there has been proposed a method of calculating the bone mineral density from a database of the average pixel value of the bone at the measurement point and the relationship between the thickness of the aluminum step and the pixel value with respect to the imaging conditions. In this method, based on a database for imaging conditions, a target site of a subject can be independently imaged without an aluminum step, and bone mineral density can be calculated.

JP 2006-334046 A

  However, the above-mentioned method is not particularly problematic, but according to the study of the present inventors, the accuracy of the bone mineral quantification obtained from the database for the imaging conditions is reduced due to the temporal change of the imaging system and the like, There is a concern that the reliability of the salt quantitative measurement may be reduced.

  An object of the present invention is to provide a medical image processing apparatus capable of maintaining the reliability of quantitative measurement of bone mineral when a target site of a subject is imaged without juxtaposing an aluminum standard member.

  The medical image processing apparatus according to the embodiment can access the storage unit. The storage unit associates and stores an aluminum standard image obtained by X-ray imaging of an aluminum standard member whose thickness changes continuously or stepwise, and pixel values of at least two thicknesses in the aluminum standard image.

  The image processing unit includes an obtaining unit, a reading unit, and a measuring unit.

  The acquisition unit acquires an object image obtained by X-ray imaging a region including at least two pieces of aluminum having the same thickness as the at least two thicknesses and a bone part to be measured.

  The reading unit reads an aluminum standard image in the storage unit based on pixel values of the at least two pieces of aluminum in the target image.

  The measuring means measures the value of the bone mineral quantification in the predetermined area based on the read pixel values in the aluminum standard image and the pixel values in a predetermined area in the bone in the target image. .

FIG. 1 is a schematic diagram illustrating a medical image processing apparatus according to the first embodiment and a peripheral configuration thereof. FIG. 2 is a schematic diagram for explaining an aluminum piece in the embodiment. FIG. 3 is a schematic diagram for explaining a database of aluminum standard images in the embodiment. FIG. 4 is a schematic diagram for explaining a measurement function in the embodiment. FIG. 5 is a flowchart for explaining the operation in the embodiment. FIG. 6 is a flowchart for explaining the operation in the embodiment. FIG. 7 is a schematic diagram for explaining the operation in the embodiment. FIG. 8 is a schematic diagram for explaining the operation in the embodiment. FIG. 9 is a schematic diagram for explaining the operation in the embodiment. FIG. 10 is a schematic diagram for explaining a database of aluminum standard images in the second embodiment. FIG. 11 is a flowchart for explaining the operation in the embodiment. FIG. 12 is a schematic diagram for explaining a region of interest ROI in the third embodiment. FIG. 13 is a schematic diagram for explaining an example of mounting the X-ray detector in the embodiment.

  Hereinafter, a medical image processing apparatus and the like according to the embodiment will be described with reference to the drawings.

<First embodiment>
FIG. 1 is a schematic diagram illustrating a configuration of an image diagnostic system including a medical image processing apparatus according to the first embodiment, and FIG. 2 is a schematic diagram illustrating an aluminum piece in the system. FIG. 3 is a schematic diagram for explaining a database of aluminum standard images in the system.
In this image diagnostic system, an X-ray diagnostic apparatus 1, an image server apparatus 20, and a medical image processing apparatus 30 are communicably connected to each other via a network 40. These devices 1, 20 and 30 may be connected wirelessly instead of the network 40.

  Here, the X-ray diagnostic apparatus 1 includes an X-ray generator 2, an X-ray diaphragm 3, an imaging table 4, an X-ray detector 5, a moving support mechanism 6, a support mechanism drive circuit 7, a storage circuit 8, and an input interface circuit. 9, a control circuit 10, an image generation circuit 11, a display circuit 12, and a network interface circuit 13.

  The X-ray generator 2 has an X-ray tube and a high voltage generator. The high voltage generator generates a tube current to be supplied to the X-ray tube and a tube voltage to be applied to the X-ray tube. The high voltage generator supplies a tube current and a tube voltage suitable for X-ray imaging to the X-ray tube. Specifically, the high-voltage generator generates a tube voltage and a tube current in accordance with the imaging conditions, under the control of the control circuit 10.

  The X-ray tube generates X-rays from an X-ray focal point (hereinafter, referred to as a tube focal point) based on a tube current supplied from the high-voltage generator and a tube voltage applied by the high-voltage generator. I do. The generated X-rays are emitted from an X-ray emission window in the X-ray tube.

  The X-ray diaphragm 3 is provided on the front surface of the X-ray generator 2 and between the X-ray generator 2 and the X-ray detector 5. Specifically, the X-ray diaphragm 3 is provided in front of the X-ray emission window in the X-ray generation unit 2. The X-ray diaphragm 3 is also called an X-ray movable diaphragm or an irradiation range limiter. The X-ray aperture device 3 has a maximum aperture irradiation range (hereinafter, referred to as a maximum irradiation range) in order to prevent the X-rays generated by the X-ray generation unit 2 from being exposed to unnecessary portions other than the imaging part desired by the operator. Is limited to a predetermined irradiation range. The X-ray diaphragm 3 limits the irradiation range by moving a lead diaphragm blade in accordance with the irradiation range limitation instruction input by the input interface circuit 9 or a predetermined limitation condition. For example, the X-ray diaphragm 3 includes a plurality of rectangular first-direction diaphragm blades movable in a first horizontal direction so as to sandwich the irradiation range, and a plurality of rectangular first-direction diaphragm blades that are orthogonal to the first horizontal direction so as to sandwich the irradiation range. And a plurality of rectangular second direction diaphragm blades movable in the horizontal direction. The X-ray diaphragm 3 has a plurality of filters (hereinafter, referred to as additional filters) inserted into the X-ray irradiation field for the purpose of reducing the exposure dose to the subject H and improving the image quality. You may. The additional filter is also called an X-ray filter, a filter plate, a beam filter, a quality filter, a compensation filter, or a beam spectrum filter.

  As shown in FIG. 2, the imaging table 4 is provided on the X-ray detector 5 and is a table on which the subject H is placed. For example, a transparent acrylic plate or a glass plate can be used as appropriate. ing. The imaging table 4 may be provided with at least two aluminum pieces 14a, 14b,... Made of the same material as the aluminum standard member, for example, at a position sandwiching the base of the left index finger of the subject H. Here, when the pixel values of at least two thicknesses in the aluminum standard image are recorded in the database DB1, the at least two aluminum pieces 14a, 14b,... Have the same thickness as the at least two thicknesses. In the present embodiment, a case where two aluminum pieces 14a and 14b are provided will be described as an example. For example, the aluminum piece 14a has the same thickness as the thinnest part of the aluminum standard member. The aluminum piece 14b has the same thickness as the thickest part of the aluminum standard member. However, the aluminum pieces 14a and 14b may be replaced with each other. Further, the aluminum pieces 14a and 14b may each have a thickness of a portion different from the thinnest portion and the thickest portion among the portions of the aluminum standard member. FIG. 2 shows an example of the shape of the aluminum pieces 14a and 14b having a cylindrical shape. However, any shape such as an elliptical shape or a polygonal shape can be used as long as the thickness is constant. Such aluminum pieces 14a and 14b may be detachably provided on the imaging table 4 or the X-ray detector 5 via, for example, an adhesive. When the aluminum pieces 14a and 14b are detachably or fixedly provided on the X-ray detector 5, the imaging table 4 is omitted. In particular, when the aluminum pieces 14a and 14b are fixedly provided on the X-ray detector 5, the X-ray diagnostic apparatus 1 is provided as a dedicated apparatus for bone mineral quantification measurement, and steps ST1 to ST3 described below are omitted. Further, “aluminum piece” may be appropriately read as “aluminum structure”, “aluminum sample”, “aluminum jig”, “sample jig”, “aluminum plate” or “aluminum standard piece”. .

  The X-ray detector 5 detects X-rays generated from the X-ray generation unit 2 and transmitted through the subject H and the imaging table 4. The X-ray detector 5 may be, for example, a flat panel detector (Flat Panel Detector: FPD). The FPD has a plurality of semiconductor detection elements. Semiconductor detection elements include a direct conversion type and an indirect conversion type. The direct conversion type is a type in which incident X-rays are directly converted into electric signals. The indirect conversion type is a type in which incident X-rays are converted into light by a phosphor and the light is converted into an electric signal.

  In either case, the plurality of semiconductor detection elements generate an electric signal in accordance with the incidence of X-rays, and convert the electric signal into an analog-to-digital converter (not shown). Output). The A / D converter converts the electric signal into digital data and outputs the digital data to a pre-processing unit (not shown).

  The movement support mechanism 6 is driven by a support mechanism drive circuit 7 and supports, for example, the X-ray generator 2 and the X-ray aperture device 3 so as to be movable in the vertical direction. Note that the movement support mechanism 6 may support the imaging table 4 and the X-ray detector 5 movably in the vertical direction. In any case, the moving support mechanism 6 is configured to control the distance between the focus of X-ray generation in the X-ray tube and the X-ray detector 5 (source image distance (hereinafter referred to as SID)). The X-ray generator 2, the X-ray diaphragm 3, and the X-ray detector 5 are supported so that can be changed.

  However, it is not essential that the movement support mechanism 6 moves the position of each element such as the X-ray generator 2, the X-ray diaphragm 3, the imaging table 4, and the X-ray detector 5, and for example, the X-ray diagnostic apparatus 1 When the device is a dedicated device for salt quantitative measurement and the SID is fixed, each element may be fixed and supported. In addition, in the case other than the bone mineral quantification measurement for the second metacarpal bone of the subject H, the moving support mechanism 6 moves the X-ray generator 2 and the X-ray restrictor 3 around the horizontal axis along the horizontal direction. It may be rotated. Similarly, the movement support mechanism 6 moves the X-ray generation unit 2, the X-ray aperture device 3, and the X-ray detector 5 to a position centered on the horizontal axis in cases other than the bone mineral quantitative measurement for the second metacarpal bone of the subject H. And may be rotated.

  The support mechanism drive circuit 7 is controlled by the control circuit 10, and drives the movement support mechanism 6 to perform the above-described vertical movement or rotation about the horizontal axis.

  A preprocessing unit (not shown) executes preprocessing on digital data output from the X-ray detector 5. The pre-processing includes correction of non-uniformity of sensitivity between channels in the X-ray detector 5 and correction of dropping of data. The preprocessed digital data is output to the image generation circuit 11.

  The storage circuit 8 includes a memory for recording electrical information such as a read only memory (ROM), a random access memory (RAM), a hardware disk drive (HDD), and an image memory, and a memory controller and a memory interface attached to the memory. It is composed of peripheral circuits. The storage circuit 8 stores a control program for the X-ray diagnostic apparatus 1, a diagnostic protocol, an operator's instruction input from the input interface circuit 9, various data groups such as imaging conditions, and various X-rays generated by the image generation circuit 11. A line image or the like is stored.

  The input interface circuit 9 includes a trackball for inputting various instructions, instructions, information, selections, and settings from an operator, a switch button, a mouse, a keyboard, a touchpad for performing an input operation by touching an operation surface, and a display. It is realized by a touch panel display or the like in which a screen and a touch pad are integrated. The input interface circuit 9 is connected to the control circuit 10, converts an input operation received from an operator into an electric signal, and outputs the electric signal to the control circuit 10. In the present specification, the input interface circuit 9 is not limited to one having physical operation components such as a mouse and a keyboard. For example, an example of the input interface circuit 9 also includes an electric signal processing circuit that receives an electric signal corresponding to an input operation from an external input device provided separately from the device and outputs the electric signal to the control circuit 10. It is.

  The control circuit 10 includes a CPU (Central Processing Unit) and a memory (not shown). The control circuit 10 performs X-ray imaging of an area including two aluminum pieces and a bone part to be measured in accordance with an operator's instruction input from the input interface circuit 9 and a control program and imaging conditions in the storage circuit 8. In order to generate the target image, each unit in the X-ray diagnostic apparatus 1 is controlled. For example, the control circuit 10 controls the X-ray generator 2 and the X-ray diaphragm 3 according to a control program, an operator's instruction (eg, irradiation range, SID), and imaging conditions (eg, tube voltage, tube current, irradiation time). And the support mechanism drive circuit 7 and the like.

  The image generation circuit 11 is controlled by the control circuit 10, generates an X-ray image (target image) based on digital data received from a preprocessing unit (not shown), and stores the target image in the storage circuit 8 and the display circuit 12. Output.

  The display circuit 12 includes a display for displaying medical images and the like, an internal circuit for supplying a display signal to the display, and peripheral circuits such as connectors and cables for connecting the display and the internal circuit. The display circuit 12 can display various X-ray images generated by the image generation circuit 11.

  The network interface circuit 13 is a circuit for connecting the X-ray diagnostic apparatus 1 to the network 40 and communicating with the image server apparatus 20 and the medical image processing apparatus 30. As the network interface circuit 13, for example, a network interface card (NIC) can be used. In the following description, description that the network interface circuit 13 intervenes in communication with the image server device 20 or the medical image processing device 30 or the like will be omitted.

  The image server device 20 includes a storage circuit 21, a processing circuit 22, and a network interface circuit 23.

  The storage circuit 21 includes a memory for recording electrical information such as a ROM, a RAM, a HDD, and an image memory, and peripheral circuits such as a memory controller and a memory interface that are associated with the memory. Such a storage circuit 21 is accessible from the medical image processing apparatus 30 via the network interface circuit 23 and the processing circuit 22. Further, the storage circuit 21 stores the control program of the image server apparatus 20, the target image transferred from the X-ray diagnostic apparatus 1 or the medical image processing apparatus 30, the database DB1 of the aluminum standard image as shown in FIG. Is stored. In the aluminum standard image, only an aluminum standard member (aluminum standard member) having a thinnest portion at one end and a thickest portion at the other end and having a continuously or stepwise varying thickness was X-rayed. It is an X-ray image and can be identified by the aluminum standard image file name. In the present embodiment, an aluminum standard image obtained by X-ray imaging of an aluminum slope having a continuously changing thickness is used. However, the present invention is not limited to this. You may. The irradiation time of each of the aluminum standard images is controlled to be constant at the time of imaging of the aluminum standard member from the viewpoint of making the imaging conditions constant. For example, even if the user releases the imaging switch (exposure switch) quickly, unlike normal imaging, when imaging an aluminum standard member, X-rays are emitted for the irradiation time set in the imaging conditions. The same applies to the bone mineral quantitative measurement in which the left hand of the subject H is radiographed. However, the database DB1 of the target image and the aluminum standard image can be mounted in a form that is not stored in the image server device 20, and may be stored in the storage circuit 31 of the medical image processing device 30, for example. That is, the target image may be transferred from the X-ray diagnostic apparatus 1 to the medical image processing apparatus 30 without passing through the image server apparatus 20. The database DB1 can be stored in any storage unit as long as the storage unit is accessible from the processing circuit 33 of the medical image processing apparatus 30. Further, the term "database" may be read as "management table", "attribute table", "management information" or "attribute information".

  Here, the database DB1 records an aluminum standard image (via an aluminum standard image file name) and pixel values of at least two thicknesses in the aluminum standard image in association with each other. In the present embodiment, the pixel value of the thinnest portion and the pixel value of the thickest portion are used as the pixel values of at least two thicknesses. However, the database DB1 is not limited to this, and for example, the shooting conditions of the aluminum standard image and the actual values (actual data) of the shooting conditions may be further associated and recorded. As the imaging conditions, for example, a tube voltage [kV] and a tube current [mA] of the X-ray tube, an X-ray irradiation time [mS], and the like can be appropriately used. The actual value is an actual value of an imaging condition, and for example, an actual tube voltage [kV], an actual tube current [mA], an actual irradiation time [mS], and the like can be appropriately used. Furthermore, the database DB1 may record, for example, the FPD S / N, SID, FPD temperature, and other information in association with each other. FPD S / N is a signal-to-noise ratio of the X-ray detector 5.

  The processing circuit 22 has a function of writing the target image transferred from the X-ray diagnostic apparatus 1 or the medical image processing apparatus 30 to the storage circuit 21. In addition, the processing circuit 22 has a function of returning the aluminum standard image and the database information read from the database DB1 in the storage circuit 21 based on the inquiry request transmitted from the medical image processing device 30.

  The network interface circuit 23 is a circuit for connecting the image server device 20 to the network 40 and communicating with the X-ray diagnostic apparatus 1 and the medical image processing apparatus 30. As the network interface circuit 23, for example, a network interface card (NIC) can be used. In the following description, description that the network interface circuit 23 is interposed in communication with the X-ray diagnostic apparatus 1 or the medical image processing apparatus 30 or the like will be omitted.

  The medical image processing device 30 includes a storage circuit 31, an input interface circuit 32, a processing circuit 33, a display circuit 34, and a network interface circuit 35.

  The storage circuit 31 includes a memory for recording electrical information such as a ROM, a RAM, an HDD, and an image memory, and peripheral circuits such as a memory controller and a memory interface that are attached to the memory. The storage circuit 31 stores the control program for the medical image processing apparatus 30, the target image transferred from the X-ray diagnostic apparatus 1 or the image server apparatus 20, the aluminum standard image retrieved from the image server apparatus 20, and the aluminum standard image. It stores database information and the like. When the image server device 20 does not hold the aluminum standard image database DB1, the storage circuit 31 further stores the aluminum standard image database DB1.

  The input interface circuit 32 performs an input operation by touching a trackball, a switch button, a mouse, a keyboard, and an operation surface for inputting various instructions, instructions, information, selections, and settings from the operator to the medical image processing apparatus 30. It is realized by a touch pad to be performed, a touch panel display in which a display screen and a touch pad are integrated, and the like. The input interface circuit 32 is connected to the processing circuit 33, converts an input operation received from the operator into an electric signal, and outputs the electric signal to the processing circuit 33. In the present specification, the input interface circuit 32 is not limited to the one having physical operation components such as a mouse and a keyboard. For example, an example of the input interface circuit 32 includes an electric signal processing circuit that receives an electric signal corresponding to an input operation from an external input device provided separately from the device and outputs the electric signal to the processing circuit 33. It is.

  The processing circuit 33 reads a control program stored in the storage circuit 31 based on a start instruction input by the operator via the input interface circuit 32, and controls the operation of the medical image processing apparatus 30 in accordance with the control program. . For example, the processing circuit 33 controls each unit according to the control program read from the storage circuit 31. In addition, the processing circuit 33 executes each function for maintaining the reliability of the bone mineral quantification measurement when the target part of the subject is imaged without juxtaposing the aluminum standard member. Here, each function includes, for example, an acquisition function 33a, a reading function 33b, and a measurement function 33c.

  The acquisition function 33a is a function of acquiring a target image in which an area including at least two pieces of aluminum and a bone part to be measured is X-rayed. Here, the at least two aluminum pieces have the same thickness as at least two thicknesses of the aluminum standard member in which the pixel values are recorded in the database DB1. In the example of the present embodiment, the two aluminum pieces 14a and 14b have the same thickness as the thinnest part and the thickest part of the aluminum standard member. The acquisition destination of the target image is the X-ray diagnostic apparatus 1 or the image server apparatus 20. When the acquisition destination is the X-ray diagnostic apparatus 1, the acquiring function 33a acquires (receives) the target image transferred from the X-ray diagnostic apparatus 1. When the acquisition destination is the image server device 20, the acquisition function 33a transmits an inquiry request to the image server device 20, and acquires (receives) the target image returned from the image server device 20. Note that the acquisition function 33a may acquire the target image and also acquire the imaging condition of the target image and the actual value of the imaging condition. The shooting condition of the target image and the actual value of the shooting condition are included in, for example, incidental information of the target image.

  The reading function 33b is a function of reading an aluminum standard image in the storage circuit 21 based on the pixel values of at least two pieces of aluminum in the acquired target image. When the image server device 20 does not hold the database of the aluminum standard image and the storage circuit 31 stores the database of the aluminum standard image, the reading function 33b replaces the storage circuit 21 with the storage circuit 31. Read out the aluminum standard image. In any case, the reading function 33b may read the aluminum standard image based on the acquired shooting conditions and actual values of the target image and the pixel values of at least two pieces of aluminum. Further, the terms “read function” and “read” for the aluminum standard image may be read as “acquisition function” and “acquire”, respectively, as long as they are not confused with the acquisition function 33a for the target image.

  The measurement function 33c measures the value of the bone mineral quantification in the predetermined area based on the pixel value in the aluminum standard image read by the reading function 33b and the pixel value in the predetermined area in the bone part in the target image. Function. Here, as shown in FIG. 4, the measuring function 33c extracts at least two images of the aluminum pieces 14a and 14b from the target image tg, and sets a straight line connecting the images of the at least two aluminum pieces 14a and 14b as at least one side. A region of interest ROI for the bone may be determined. When the two aluminum pieces 14a and 14b are provided at positions sandwiching the base of the left index finger of the subject H, the region of interest ROI can be easily obtained by setting a straight line connecting the images of the two aluminum pieces 14a and 14b as one side. It is. Further, the measurement function 33c may extract the predetermined region AR from the obtained region of interest ROI, and measure the value of the bone mineral quantification based on the extracted pixel value of the predetermined region AR. In the case of the DIP method, the predetermined area AR is a range of 10% of the bone length at the center of the second metacarpal bone.

  In the embodiment shown in FIG. 1, each function executed by the processing circuit 33 is stored in the storage circuit 31 in the form of a program executable by a computer. The processing circuit 33 is a processor that reads out a program from the storage circuit 31 and executes the program to realize a function corresponding to each program. In other words, the processing circuit from which each program has been read has each function shown in the processing circuit 33 of FIG. Although FIG. 1 has been described assuming that each function is realized by a single processing circuit 33, a plurality of independent processors are combined to form a processing circuit, and each processor executes a program. Each function may be realized.

  The display circuit 34 includes a display for displaying medical images and the like, an internal circuit for supplying a display signal to the display, and peripheral circuits such as connectors and cables for connecting the display and the internal circuit. The display circuit 34 displays the target image stored in the storage circuit 31. Further, the display circuit 34 may display the aluminum standard image in the storage circuit 31 while displaying the target image. In this case, the display circuit 34 may superimpose the aluminum standard image on the target image or display the aluminum standard image and the target image side by side on the left and right. Alternatively, the display circuit 34 may display the acquired target image and the measured value of the bone mineral quantification without displaying the aluminum standard image.

  The network interface circuit 35 is a circuit for connecting the medical image processing apparatus 30 to the network 40 and communicating with the X-ray diagnostic apparatus 1 and the image server apparatus 20. As the network interface circuit 35, for example, a network interface card (NIC) can be used. In the following description, description that the network interface circuit 35 intervenes in communication with the X-ray diagnostic apparatus 1 or the image server apparatus 20 or the like will be omitted.

  Next, the operation of the diagnostic imaging system configured as described above will be described with reference to the flowcharts of FIGS. 5 and 6 and the schematic diagrams of FIGS.

  First, in the X-ray diagnostic apparatus 1, the left hand of the subject H is placed on the imaging table 4, and a selection screen for selecting an imaging method is displayed on the display circuit 12. In this selection screen, it is assumed that, for example, an imaging technique for bone mineral quantitative measurement or an ordinary imaging technique can be selected with a radio button or the like. It is also assumed that this selection screen includes input fields for imaging conditions such as a tube voltage, a tube current, and an irradiation time of the X-ray tube.

  While such a selection screen is being displayed, in the input interface circuit 9, as shown in FIG. 5, a photographing condition is input and a photographing method is selected according to a user operation such as a doctor (step ST1). The control circuit 10 determines whether or not the selected imaging method is a measurement of bone mineral quantification (step ST2). If not, the control circuit 10 controls each unit to execute normal imaging.

  As a result of the determination in step ST2, in the case of measurement of bone mineral quantification, the control circuit 10 determines whether or not the input imaging condition has been registered in the database DB1 (step ST4). A warning is displayed on the display circuit 12 (step ST5), and photographing is prohibited. That is, if an attempt is made to perform X-ray imaging under conditions other than the imaging conditions of the aluminum standard image registered in the database DB1, a warning is displayed before the imaging that the imaging conditions of the aluminum standard image have not been registered, and the imaging is prohibited. it can. Thereafter, the control circuit 10 causes the display circuit 12 to display a selection screen before selecting an imaging condition and an imaging method, and executes the processing after step ST1 again.

  On the other hand, if the result of determination in step ST4 is that the input shooting condition has been registered, the control circuit 10 sets the shooting condition in the storage circuit 8 (step ST6). If necessary, the user operates the input interface circuit 9, and the control circuit 10 sets the distance SID between the source image receiving planes in the support mechanism drive circuit 7 according to the operation, and controls the X-ray irradiation range. Then, the X-ray diaphragm 3 is set (step ST7). Thus, the X-ray diagnostic apparatus 1 can perform X-ray imaging of the subject H under the same conditions as the imaging conditions and the SID in the database DB1.

  Subsequently, in the X-ray diagnostic apparatus 1, when the imaging switch included in the input interface circuit 9 is pressed down by the user (step ST8), the X-ray of the left hand of the subject H is obtained according to the imaging conditions in the storage circuit 8. Imaging is performed (step ST9). At this time, the X-ray diagnostic apparatus 1 emits X-rays during the irradiation time set in the imaging conditions, unlike normal imaging, even if the user releases the imaging switch (exposure switch) quickly, for example. That is, in the X-ray diagnostic apparatus 1, the X-ray generator 2 generates X-rays according to the imaging conditions of the tube voltage, the tube current, and the irradiation time, and the X-ray diaphragm 3 narrows the irradiation range of the X-rays. The X-rays whose irradiation range has been narrowed are transmitted through the left hand of the subject H and the imaging table 4 and detected by the X-ray detector 5. The X-ray detector 5 outputs an electric signal corresponding to an X-ray detection result to an A / D converter (not shown). The A / D converter converts the electric signal into digital data and outputs the digital data to the image generation circuit 11 via a preprocessing unit (not shown). The image generation circuit 11 generates an X-ray image (target image) based on the digital data received from the preprocessing unit, and outputs the target image to the storage circuit 8 and the display circuit 12.

  After the end of imaging, the X-ray diagnostic apparatus 1 determines whether or not X-ray imaging has failed according to the operation of the input interface circuit 9 by the user (step ST10). 12 and the process ends (step ST11). Supplementally, the user visually recognizes the target image displayed on the display circuit 12 and selects a shooting success button or a shooting failure button displayed on the display circuit 12 by operating the input interface circuit 9. The control circuit 10 performs the determination in step ST10 according to this operation.

  On the other hand, as a result of the determination in step ST10, when the X-ray imaging is successful, the control circuit 10 sets the target image including the imaging conditions in the storage circuit 8 and the actual value received from the X-ray generation unit 2 in the supplementary information. The data is stored in the storage circuit 8.

  Next, as shown in FIG. 7, in the medical image processing apparatus 30, the acquisition function 33a of the processing circuit 33 accesses the storage circuit 8 of the X-ray diagnostic apparatus 1 by operating the input interface circuit 32 by a user such as a doctor. Then, the last saved target image tg is obtained from the storage circuit 8. Accordingly, the acquisition function 33a of the processing circuit 33 acquires the imaging condition, the actual value of the imaging condition, and the target image tg (steps ST12 to ST13).

  After step ST13, the processing circuit 33 determines whether or not the images of the two aluminum pieces 14a and 14b have been extracted from the acquired target image tg as shown in FIG. 6 (step ST14). If the result of this determination is negative, a region of interest ROI is extracted from the target image tg by the automatic shutter function (step ST15). Here, the auto shutter function is a function of cutting out an X-ray irradiation range from an X-ray image. After step ST15, the processing circuit 33 transmits an inquiry request including the shooting conditions and the actual value of the target image tg to the image server device 20, as shown in FIG.

  The image server device 20 searches the database DB1 based on the inquiry request. As a result of the search, when there is an aluminum standard image associated with the imaging condition and the actual value that matches the imaging condition and the actual value of the target image tg (step ST16: Yes), the aluminum standard image ag is converted to a medical image processing apparatus. Reply to 30.

  Thereby, in the medical image processing apparatus 30, the reading function 33b of the processing circuit 33 obtains, from the database DB1, the aluminum standard image ag associated with the imaging condition and the actual value that match the imaging condition and the actual value of the target image tg. (Step ST17). After step ST17, the processing circuit 33 proceeds to step ST22.

  Further, as a result of the search, when there is no aluminum standard image ag (step ST16: No), the image server device 20 returns to the medical image processing device 30 that there is no aluminum standard image corresponding to the inquiry. In the medical image processing device 30, upon receiving this reply, the processing circuit 33 proceeds to step ST21.

  On the other hand, if the result of determination in step ST14 is negative, as shown in FIG. 8, the processing circuit 33 extracts a region of interest ROI from the target image tg with the two aluminum pieces 14a and 14b as base points (step ST18). ). For example, the region of interest ROI relating to the bone may be obtained with a straight line connecting the images of the two aluminum pieces 14a and 14b extracted from the target image tg as one side. In FIG. 8, a region of interest ROI is a region relating to the second metacarpal of the subject H.

  The processing circuit 33 searches the database DB1 based on the pixel values of the two aluminum pieces 14a and 14b having the same thickness as the thinnest part and the thickest part, respectively (step ST19). At this time, the processing circuit 33 determines whether or not there is a pixel value that matches the pixel value of each of the aluminum pieces 14a and 14b (step ST20). If there is a matching pixel value, the process proceeds to step ST22. If the result of step ST20 is negative, the reading function 33b of the processing circuit 33 performs an approximation based on at least one of the shooting conditions and the actual value of the target image tg and the pixel values of the aluminum pieces 14a and 14b. . That is, the reading function 33b of the processing circuit 33 acquires the aluminum standard image ag from the database DB1 by such approximation (step ST21).

  The "approximation" referred to in step ST21 is to search for the aluminum standard image ag having the pixel value closest to the pixel value of each of the aluminum pieces 14a and 14b (or the shooting condition and the actual value closest to the shooting condition of the target image and the actual value). May be performed. Alternatively, the “approximation” referred to in step ST21 may be a process of searching for the aluminum standard image ag according to the result of the approximation calculation based on the shooting conditions and the actual value. As the approximate calculation, for example, a calculation for obtaining an intermediate value between the imaging condition and the actual value, a calculation for obtaining a pixel value interpolated or weighted based on the imaging condition and the actual value, and the like can be appropriately used. The calculation of the interpolated or weighted pixel value pw is performed, for example, when the pixel value in the case of the tube voltage of 50 kV and the actual value of 49 kV is pm, and the imaging condition: pw = actual value: pm, and pw = pm × The photographing condition / actual value may be set to pm × 50/49. That is, the approximation calculation may be, for example, a calculation that approximately corrects the pixel value pm corresponding to the actual value to the pixel value pw corresponding to the imaging condition. Further, a process of searching for an aluminum standard image ag having a value closest to the result of the approximation calculation may be performed by combining the search for the near value and the approximation calculation.

In any case, after the end of step ST21, the processing circuit 33 determines a predetermined area AR necessary for measuring the bone mineral quantification of the second metacarpal bone of the subject H from the region of interest ROI extracted in step ST15 or ST18. Extract (Step ST22).
Next, the processing circuit 33 displays, for example, a message inquiring whether to display the aluminum standard image ag in parallel on the screen, and displays the aluminum standard image ag in parallel according to the operation of the input interface circuit 9 by the user. It is determined whether or not (step ST23). In the case of parallel display, as shown in FIG. 7, the target image tg and the aluminum standard image ag are displayed in parallel (step ST24), and the process proceeds to step ST25. In step ST23, the presence or absence of the parallel display may be set in the storage circuit 8 in advance, and the determination based on the setting may be performed.

  If the result of determination in step ST23 is negative, the measurement function 33c of the processing circuit 33 determines a predetermined area based on the pixel value in the aluminum standard image ag and the pixel value of the predetermined area AR extracted in step ST22. The value of the bone mineral quantification of AR is calculated (step ST25). For example, the measurement function 33c obtains the distribution of the pixel values (density) of the bone along the bone width direction in the predetermined area AR at about a dozen locations, and obtains the average of these distributions. Next, the pixel value of the bone in the averaged distribution is converted into the thickness of the aluminum standard member corresponding to the pixel value (density) of the aluminum standard image ag that matches the pixel value of the bone, and the bone density GS (the aluminum thickness) is calculated. Conversion value). Here, in the case of an aluminum slope, the aluminum standard member has a predetermined inclination such that the thickness changes 1 mm when the aluminum standard member advances 10 mm in the longitudinal direction. Similarly, in the case of the aluminum step, there is a step having a predetermined relationship between the position in the longitudinal direction and the thickness. For this reason, the pixel value of the aluminum standard image ag can be converted into the thickness of the aluminum standard member from the position of the pixel value. Subsequently, the obtained integral value ΣGS of the bone density GS is divided by the bone width D to obtain a value of the bone mineral quantification (ΣGS / D (mmAl)). The invention is not limited thereto, and any calculation method based on the DIP method can be used for calculating the value of the bone mineral quantification. For example, after dividing the integral value of the pixel value of the bone in the averaged distribution by the bone width, the result of the division may be converted to the thickness of the aluminum standard member.

  In any case, the processing circuit 33 displays the calculated value of the bone mineral quantification on the screen by the display circuit 34 (step ST26). When the process proceeds from step ST24 to step ST25, the display circuit 34 displays the target image tg, the aluminum standard image ag, and the value of the bone mineral quantification. When the process proceeds from step ST23 to step ST25, for example, as shown in FIG. 9, the aluminum standard image ag is not displayed, and the target image tg and the value of the bone mineral quantification are displayed by the display circuit. In step ST26, a region of interest ROI extracted from the target image tg may be displayed instead of the target image tg.

  As described above, according to the present embodiment, a target image in which a region including at least two pieces of aluminum having the same thickness as at least two thicknesses and a bone part to be measured is X-rayed is acquired. An aluminum standard image is read based on pixel values of at least two pieces of aluminum in the target image. Based on the read pixel values in the aluminum standard image and the pixel values in a predetermined region in the bone portion in the target image, the value of the bone mineral quantification in the predetermined region is measured.

  Therefore, when the target site of the subject is imaged without juxtaposing the aluminum standard member, the reliability of the bone mineral quantitative measurement can be maintained.

  Supplementally, even if the image is taken without juxtaposing the aluminum standard member, the brightness (pixel value) of the bone of the target image and the brightness (pixel value) of the target image are managed in the database DB1 by the images of at least two aluminum pieces 14a and 14b in the target image. The same as the luminance (pixel value) of the standard aluminum image.

  Further, since the aluminum standard member is not juxtaposed when imaging the subject H, the irradiation range along the longitudinal direction of the bone part (second metacarpal) to be measured can be smaller than the long side of the aluminum standard member. That is, since the irradiation range of the X-ray can be reduced, unnecessary exposure can be reduced.

  In addition to this, even if an area including the bone part to be measured is photographed without juxtaposing the aluminum standard member, the aluminum standard image ag is managed in the database DB1, so that the target image tg and the aluminum standard image ag can be managed as desired. And can be displayed in parallel.

  Alternatively, if desired, the value of the bone mineral quantification can be calculated and displayed without simultaneously displaying the aluminum standard image ag and the target image tg. Supplementally, since the value of the bone mineral quantification can be calculated based on a comparison between the pixel values of the aluminum pieces 14a and 14b and the pixel values of the aluminum standard image ag, it is necessary to simultaneously display the aluminum standard image ag and the region of interest ROI. Absent. In other words, for a user who does not need to display the aluminum standard image ag, a screen including the target image tg and the value of the bone mineral quantification may be displayed without displaying the aluminum standard image ag, as desired by the user. it can.

  Further, according to the present embodiment, the reading function 33b of the processing circuit 33 determines the aluminum standard based on the shooting condition and the actual value of the acquired target image tg and the pixel values of at least two aluminum pieces 14a and 14b. It has a function of reading the image ag. For this reason, when the aluminum standard image ag cannot be acquired from the pixel values of the aluminum pieces 14a and 14b (ST20: No), the approximation based on the pixel values of the aluminum pieces 14a and 14b and the shooting conditions and the actual value of the target image is performed. An aluminum standard image ag can be obtained. Therefore, when the bone mineral quantification measurement of the present embodiment is performed, it is possible to reduce re-examinations because an aluminum standard image cannot be obtained from the pixel values of the aluminum pieces 14a and 14b.

  According to the present embodiment, the measurement function 33c of the processing circuit 33 extracts the image of at least two aluminum pieces from the target image tg, and sets a straight line connecting the images of the at least two aluminum pieces 14a and 14b to at least one side. A region of interest ROI for the bone can be determined. Then, the predetermined region AR is extracted from the region of interest ROI, and the value of the bone mineral quantification can be measured based on the extracted pixel value of the predetermined region AR. Therefore, the measurement function 33c of the processing circuit 33 can easily extract the region of interest ROI when the easily identifiable images of at least two aluminum pieces 14a and 14b are used at both ends of one side of the region of interest ROI.

<Second embodiment>
Next, an image diagnostic system including a medical image processing apparatus according to the second embodiment will be described. The second embodiment is a modification of the first embodiment, and stores a target image database DB2 in the storage circuit 21 of the image server device 20 or the storage circuit 31 of the medical image processing device 30 as shown in FIG. are doing. Hereinafter, a case where the database DB2 is stored in the storage circuit 21 of the image server device 20 will be described as an example.

  As described above, the target image is an image obtained by X-ray imaging of a region including at least two aluminum pieces each having the same thickness as at least two thicknesses whose pixel values are recorded in the database DB1 and a bone part to be measured. It is. The two aluminum pieces of this embodiment have the same thickness as the thinnest part and the thickest part of the aluminum standard member. The target image can be identified by the target image file name.

  Here, the target image database DB2 includes target images captured in the past inspection (via the target image file name), shooting conditions of the target images captured in the past inspection, and actual values of the shooting conditions. Are recorded in association with each other. However, the database DB2 is not limited to this, and may record, for example, the FPD S / N, SID, FPD temperature, and other information in association with each other. Note that the target image database DB2 can be mounted in the image server device 20 in the same manner as the above-described database DB1, and may be stored in the medical image processing device 30, for example.

  Accordingly, the input interface circuit 32 of the medical image processing apparatus 30 inputs a shooting condition of a target image shot in the past examination and an actual value of the shooting condition by a user operation.

  As described above, the aluminum standard image DB1 records the aluminum standard image, the shooting conditions of the aluminum standard image, the actual value of the shooting condition, the pixel value of the thinnest portion, and the pixel value of the thickest portion in association with each other. . However, the pixel value of the thinnest portion and the pixel value of the thickest portion may be pixel values of at least two thicknesses in the aluminum standard image, as described above.

  The acquisition function 33a of the processing circuit 33 of the medical image processing apparatus 30 has a function of acquiring a target image from the database DB2 in the storage circuit 21 based on the imaging conditions and actual values input by the input interface circuit 32.

  The reading function 33b of the processing circuit 33 is a function of reading an aluminum standard image from the database DB1 based on the shooting conditions and actual values input by the input interface circuit 32 and the pixel values of at least two pieces of aluminum in the target image. Have.

  Next, the operation of the diagnostic imaging system configured as described above will be described with reference to the flowchart of FIG. In the flowchart of FIG. 11, the same processes as those in FIGS. 5 and 6 are denoted by the same step numbers, and detailed description thereof will be omitted. Here, different operations will be mainly described. That is, the flowchart of FIG. 11 indicates that steps ST12a and ST13a surrounded by a broken line are executed instead of steps ST1 to ST13 described above.

  Now, it is assumed that the database DB2 of the target image is stored in the storage circuit 21 of the image server device 20.

  At this time, in the medical image processing apparatus 30, the input interface circuit 32 inputs the imaging conditions of the target image captured in the past examination and the actual value of the imaging conditions to the processing circuit 33 by the user's operation (step ST12a). ).

  The acquisition function 33a of the processing circuit 33 acquires a target image from the database DB2 in the storage circuit 21 based on the input imaging conditions and actual values (step ST13a).

  Hereinafter, steps ST14 to ST26 are performed as described above. For example, the reading function 33b of the processing circuit 33 reads an aluminum standard image from the database DB1 based on the shooting condition and the actual value input in step ST12a and the pixel values of two aluminum pieces in the target image (step ST12a). ST14 to ST21). The measurement function 33c of the processing circuit 33 extracts the predetermined region AR from the region of interest ROI, and measures the value of the bone mineral quantification based on the extracted pixel values of the predetermined region AR (steps ST22 and ST25). In addition, the display circuit 34 displays the target image and the value of the bone mineral quantification, and displays an aluminum standard image as appropriate (steps ST23, ST24, ST26).

  As described above, according to the present embodiment, the image server device 20 associates the target image captured in the past inspection with the imaging condition of the target image captured in the past inspection and the actual value of the imaging condition. To remember.

  In the medical image processing apparatus 30, the imaging condition of the target image captured in the past examination and the actual value of the imaging condition are input, and based on the input imaging condition and the actual value, the target image is obtained from the image server device. get. Further, the medical image processing apparatus 30 reads an aluminum standard image based on the input imaging conditions, actual values, and pixel values of at least two aluminum pieces in the target image.

  As described above, according to the second embodiment, in addition to the operation and effect of the first embodiment, it is possible to acquire an aluminum standard image based on the photographing conditions and actual values of a target image photographed in a past inspection. Can be.

<Third embodiment>
Next, an image diagnostic system including a medical image processing apparatus according to the third embodiment will be described. The third embodiment is a modification of the first embodiment. As shown in FIG. 12, a region including at least two aluminum pieces 14a, 14b,. Region of interest ROI. Supplementally, the X-ray irradiator 3 narrows the irradiation range of the X-ray so that the region of interest ROI is set to the irradiation range 3a, so that the target image tg, the irradiation range 3a, and the region of interest ROI are made substantially the same. In the present embodiment, the case where at least two aluminum pieces 14a, 14b,... Are two is described as an example.

  Here, the measurement function 33c of the processing circuit 33 has a function of extracting a predetermined region AR in the bone part from the region of interest ROI, and measuring the value of the bone mineral quantification based on the extracted pixel value of the predetermined region AR. .

  Next, the operation of the diagnostic imaging system configured as described above will be described with reference to FIGS.

  Now, steps ST1 to ST6 are executed as described above.

  Subsequently, in the X-ray diagnostic apparatus 1, the user operates the input interface circuit 9, and the control circuit 10 sets the distance SID between the image receiving planes in the support mechanism drive circuit 7 in accordance with the operation, and The X-ray diaphragm 3 is set corresponding to the irradiation range of the line (step ST7). At this time, the X-ray irradiation range 3a is set to the range of the region of interest ROI. Accordingly, since the target image tg, the irradiation range 3a, and the region of interest ROI are substantially the same, the steps ST15 and ST18 for extracting the region of interest ROI described above become unnecessary.

  Therefore, after the end of step ST7, steps ST8 to ST14, ST16 to ST17, and ST19 to ST26 in which steps ST15 and ST18 for extracting the region of interest ROI are omitted from steps ST8 to ST26 in the same manner as described above.

  As described above, according to the present embodiment, a region including at least two aluminum pieces 14a and 14b and a bone to be measured is set as a region of interest ROI related to the bone. Here, the measurement function 33c of the processing circuit 33 extracts the predetermined region AR in the bone from the region of interest ROI, and measures the value of the bone mineral quantification based on the extracted pixel value of the predetermined region AR.

  Therefore, since the X-rays are not irradiated to a region other than the region of interest ROI, unnecessary exposure can be reduced. Specifically, exposure is reduced by setting the X-ray irradiation range 3a to be substantially the same as the region of interest ROI by the X-ray aperture device 3. Further, by arranging the aluminum pieces 14a and 14b near the region of interest ROI, the irradiation range 3a of the X-ray can be narrowed to substantially the same range as the region of interest ROI.

  In addition, since the X-ray detector 5 only needs to cover the irradiation area 3a substantially the same as the region of interest ROI, it can be mounted with a smaller FPD. As shown in FIG. 13, when the X-ray detector 5 is mounted on an FPD having substantially the same size as the region of interest ROI, the X-ray diagnostic apparatus 1 is realized, for example, as a dedicated apparatus for quantitative measurement of bone mineral. You. In this case, in addition to omitting steps ST15 and ST18 described above, steps ST1 to ST3 for selecting and executing an imaging method other than the bone mineral quantification are omitted.

  Further, since the X-ray irradiation range 3a matches the region of interest ROI, it is not necessary to specify the region of interest ROI from the target image tg. Therefore, it is possible to easily extract the predetermined region AR in the region of interest ROI. Can be. For example, when the second metacarpal in the region of interest ROI is specified and the predetermined region AR is extracted from the second metacarpal, only the region of interest ROI is cut out in advance. Can be identified.

  Although the third embodiment has been described as a modification of the first embodiment, the present invention is not limited to this, and may be a modification of the second embodiment. Accordingly, in the third embodiment, in addition to the effects of the second embodiment, it is possible to obtain the same effects as those of the target image captured in the past.

  According to at least one embodiment described above, a target image in which a region including at least two aluminum pieces each having the same thickness as at least two thicknesses and a bone part to be measured is X-rayed is acquired. An aluminum standard image is read based on pixel values of at least two pieces of aluminum in the target image. Based on the read pixel values in the aluminum standard image and the pixel values in a predetermined region in the bone portion in the target image, the value of the bone mineral quantification in the predetermined region is measured.

  Therefore, when the target site of the subject is imaged without juxtaposing the aluminum standard member, the reliability of the bone mineral quantitative measurement can be maintained.

  The term “processor” used in the above description may be, for example, a central processing unit (CPU), a graphics processing unit (GPU), or an application specific integrated circuit (ASIC), a programmable logic device (eg, an ASIC). , Simple Programmable Logic Device (SPLD), Complex Programmable Logic Device (CPLD), and Field Programmable Gate Array (FPGA). The processor realizes functions by reading and executing a program stored in the storage circuit. Instead of storing the program in the storage circuit, the program may be directly incorporated in the circuit of the processor. In this case, the processor realizes a function by reading and executing a program incorporated in the circuit. Note that each processor of the present embodiment is not limited to the case where each processor is configured as a single circuit, but may be configured as one processor by combining a plurality of independent circuits to realize its function. Good. Further, a plurality of components in FIG. 1 may be integrated into one processor to realize its function.

  The database DB1 and the storage circuit 21 or the database DB1 and the storage circuit 31 in the first embodiment are an example of a storage unit in the claims. The acquiring function 33a, the reading function 33b, and the measuring function 33c in the first embodiment are examples of an acquiring unit, a reading unit, and a measuring unit in the claims. The display circuit 34 in the first embodiment is an example of the display means and the bone mineral quantitative value display means in the claims. The database DB2 and the storage circuit 21 or the database DB2 and the storage circuit 31 in the second embodiment is an example of an image storage unit in the claims. The input interface circuit 32 in the second embodiment is an example of an input unit in the claims.

  Although some embodiments of the present invention have been described, these embodiments are presented as examples and are not intended to limit the scope of the invention. These embodiments can be implemented in other various forms, and various omissions, replacements, and changes can be made without departing from the spirit of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are also included in the invention described in the claims and equivalents thereof.

  DESCRIPTION OF SYMBOLS 1 ... X-ray diagnostic apparatus, 2 ... X-ray generation part, 3 ... X-ray diaphragm, 4 ... Imaging stand, 5 ... X-ray detector, 6 ... Moving support mechanism, 7 ... Support mechanism drive circuit, 8, 21 ... Memory circuit, 9, 32 Input interface circuit, 10 Control circuit, 11 Image generation circuit, 12, 34 Display circuit, 13, 23, 35 Network interface circuit, 14a, 14b Aluminum piece, 20 Image server Apparatus, 22, 33: Processing circuit, 30: Medical image processing apparatus, 33a: Acquisition function, 33b: Read function, 33c: Measurement function, 40: Network, DB1, DB2: Database, tg: Target image, ag: Aluminum standard image.

Claims (7)

A standard member made of aluminum whose thickness changes continuously or stepwise can be accessed to an aluminum standard image obtained by X-ray imaging and storage means for storing at least two pixel values of the aluminum standard image in association with each other. A medical image processing apparatus,
At least two pieces of aluminum having the same thickness as the at least two thicknesses, and an acquisition unit that acquires a target image in which a region including a bone part to be measured is X-rayed,
A reading unit that reads an aluminum standard image in the storage unit based on pixel values of the at least two pieces of aluminum in the target image;
Measuring means for measuring a value of bone mineral quantification in the predetermined area based on the read pixel values in the aluminum standard image and pixel values in a predetermined area in the bone portion in the target image. Medical image processing device. The storage unit stores the aluminum standard image, the shooting condition of the aluminum standard image, the actual value of the shooting condition, and the pixel value of the at least two thicknesses in association with each other,
The obtaining means obtains the target image, obtains a shooting condition of the target image and an actual value of the shooting condition,
The reading unit reads the aluminum standard image based on the imaging conditions and the actual value of the obtained target image and the pixel values of the at least two pieces of aluminum.
The medical image processing device according to claim 1. Display means for displaying the target image and the read aluminum standard image in parallel,
The medical image processing apparatus according to claim 1, further comprising: An image storage means for storing the target image captured in the past inspection and the imaging conditions of the target image captured in the past inspection and the actual value of the imaging condition in association with each other;
Input means for inputting a shooting condition of the target image shot in the past inspection and an actual value of the shooting condition,
The storage unit stores the aluminum standard image, the shooting condition of the aluminum standard image, the actual value of the shooting condition, and the pixel value of the at least two thicknesses in association with each other,
The acquisition unit acquires a target image from the image storage unit based on the input shooting conditions and the actual value,
The reading unit reads the aluminum standard image based on the input photographing conditions, the actual value, and the pixel values of the at least two aluminum pieces;
The medical image processing device according to claim 1. Without displaying the aluminum standard image, the acquired target image, the bone mineral quantification value display means for displaying the value of the measured bone mineral quantification,
The medical image processing apparatus according to claim 1, further comprising: An area including the at least two aluminum pieces and the bone part to be measured is a region of interest related to the bone part,
The measurement unit extracts a predetermined region in the bone portion from the region of interest, and measures the value of the bone mineral quantification based on a pixel value of the extracted predetermined region.
The medical image processing apparatus according to claim 1. The measurement unit extracts the image of the at least two aluminum pieces from the target image, obtains a region of interest related to the bone with a straight line connecting the images of the at least two aluminum pieces as at least one side, and calculates the region of interest from the region of interest. Extract a predetermined region, based on the pixel value of the extracted predetermined region, measure the value of the bone mineral quantification,
The medical image processing apparatus according to claim 1.