JP6626912B2 - Incense stick and method for producing the same - Google Patents

Description

  The present invention relates to an incense stick containing a volatile drug and a method for producing the same.

  Generally, what is called a mosquito coil is known as an incense for controlling pests (for example, see Patent Documents 1 to 5).

  In Patent Literature 1, an inorganic layer in which an insecticide such as a pyrethroid is blended with an inorganic material such as clay is formed to a thickness of 1/3 or less of the thickness of the base material layer, and the inorganic material layer is formed on the base material layer. , Below or in part or all of the sides.

  Patent Documents 2 to 4 disclose that a mixture of an ester compound represented by a predetermined chemical formula and a chain saturated hydrocarbon-based solvent or an alicyclic saturated hydrocarbon-based solvent is applied to an incense base. .

  Patent Literature 5 discloses a method in which a pesticidal solution containing a pesticide is mixed with a non-volatile component at room temperature to generate a liquid, and the liquid containing the non-volatile component at normal temperature is applied to the treated surface of the incense stick substrate. It is disclosed.

JP-B-46-28119 JP 2005-200403 A JP 2005-298777 A JP 2006-256991 A Japanese Patent No. 4183790

  In Patent Literature 1, the insecticide is provided in a layered manner above or below the base material layer. In the case of incense, however, the insecticide is susceptible to heat or the like when the incense stick is burned. It is considered that heat affects the insecticidal efficacy, and even if a pesticide is provided in layers as in Patent Literature 1, the extent of the insecticidal efficacy is not described in Patent Literature 1 and is unknown. is there.

  In addition, when the insecticide is applied to the incense base as in Patent Documents 2 to 4, the distribution of the insecticide in the depth direction of the incense base is determined in a gradual manner. There is a possibility that the insecticidal effect may be reduced due to the influence of heat.

  Some incense sticks contain fragrances in addition to the insecticide, and there is a demand for such incense sticks to obtain a sufficient effect while minimizing the fragrance contained.

  The present invention has been made in view of such a point, and an object of the present invention is to enhance the efficacy of a drug contained in an incense stick.

  In order to achieve the above object, in the present invention, esters having a molecular weight of not less than a predetermined value are included.

The first invention, dimefluthrin as volatile agents incense substrate, of Transfluthrin and allethrin, at least one included incense, stearic acid as a fatty acid ester 3 isoamyl-6-methyl-2 -At least one of heptyl, 2-hexyldecyl isostearate and glycerol trioleate is contained, and the base layer having a thickness of 1/16 of the total thickness of the base substrate is provided with an incense group. It is characterized in that 30% or more of the volatile agent contained in the whole material is contained .

According to this configuration, since the fatty acid ester having a molecular weight of 400 or more is contained, the drug is easily volatilized at the time of burning the incense stick, and the effective transpiration rate of the drug is improved .

In addition , since 3-isoamyl-6-methyl-2-heptyl stearate, 2-hexyldecyl isostearate and glycerol trioleate are liquids at room temperature, the workability of including them in the incense stick base in the incense stick manufacturing process Becomes better.

In addition , 3-isoamyl-6-methyl-2-heptyl stearate, 2-hexyldecyl isostearate and glycerol trioleate all have good compatibility with pyrethroid-based compounds. Workability when mixing the ester and the pyrethroid-based compound into the incense stick base material is improved.

Further, 30% or more of the volatile chemicals are unevenly distributed in the outer layer of the base material. The thickness of the outer layer portion of the base material is 1/16 of the total thickness of the incense base material, which is sufficiently smaller than the total thickness. Since 30% or more of the drug is unevenly distributed in the outer layer portion of the base material having a thickness of 1/16, the volatile agent is easily volatilized from the outer layer portion of the base material during combustion, and heat during the combustion is converted into the volatile agent. It is less likely to have an adverse effect on it. Thus, the efficacy of the drug increases.

A second invention is characterized in that the fatty acid ester and the volatile agent are applied to the incense stick substrate.

According to this configuration, the volatile drug easily stays in the outer layer portion of the incense stick substrate, and heat during combustion is less likely to adversely affect the drug .

A third invention is dimefluthrin as volatile agents incense substrate, of Transfluthrin and allethrin, in the manufacturing method of the incense, which include at least one, stearic acid as a fatty acid ester 3 isoamyl 6- among methyl-2-heptyl, isostearate 2-hexyl decyl and glycerol trioleate, after obtaining the coating stock solution by mixing at least one and a said volatile agent, the coating stock solution to the incense base coating By doing so , the base material outer layer having a thickness of 1/16 of the total thickness of the incense stick base material contains 30% or more of the volatile agent contained in the entire incense stick base material. .

A fourth invention is characterized in that the coating solution contains normal paraffin as a solvent.

  According to the present invention, since a fatty acid ester having a molecular weight of 400 or more is contained, the effective transpiration rate of a drug is improved, and the efficacy of the drug can be increased.

It is sectional drawing of the incense stick which concerns on embodiment. It is a figure explaining a repellent test method.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. Note that the description of the preferred embodiments below is merely an example in nature, and is not intended to limit the present invention, its application, or its use.

  FIG. 1 shows a cross section of an incense stick 1 according to an embodiment of the present invention. The cross section shown in FIG. 1 is a cross section in a direction orthogonal to the direction in which the incense stick 1 extends. The incense stick 1 may have, for example, a shape extending linearly or a shape extending spirally, and the shape is not particularly limited. Also, the cross-sectional shape of the incense stick 1 can be various shapes such as a rectangular cross-section, a circular cross-section, and an elliptical cross-section. In this embodiment, the incense stick 1 has a spirally extending shape, and has a cross-sectional shape close to a rectangle as shown in FIG. 1 and four corners close to a circular arc. In addition, the broken lines denoted by reference numerals L1 and L2 in FIG. 1 are described only for convenience of description when explaining the distribution of the drug described later, and are lines that are not included in the actual incense stick 1. .

  The incense stick 1 is the incense stick base material 2 containing a volatile agent and a fatty acid ester having a predetermined molecular weight or more. Examples of volatile chemicals include insecticides (pyrethroid compounds), various flavors, and the like. As insecticides, for example, dimefurthrin, transfluthrin, alesulin, dl, d-T80-aresulin, dl, dT-aresulin, d, dT-aresulin, praletrin, metofluthrin, mepafluthrin, renofluthrin, empentrin, pyrethrin, profluthrin, heptaflurin Trilin, tetraflumethrin, phthalthrin, resmethrin, phenothrin, permethrin, cyphenothrin, imiprothrin and the like can be mentioned.

  The fatty acid ester may have a molecular weight of 400 or more. The fatty acid ester can be selected to be a liquid at normal temperature. Further, when a pyrethroid compound is used as a volatile agent, a fatty acid ester having good compatibility with the pyrethroid compound can be selected. Examples of the fatty acid ester satisfying such conditions include 3-isoamyl-6-methyl-2-heptyl stearate, 2-hexyldecyl isostearate, and glycerol trioleate. It is sufficient that at least one of these fatty acid esters is contained, and any two or more thereof may be contained. In addition, a fatty acid ester having a molecular weight of 400 or more can be used.

3-isoamyl-6-methyl-2-heptyl stearate has a molecular formula of C ₂₇ H ₅₄ O ₂ and a molecular weight of 411. Isostearate 2-hexyl decyl, molecular formula is _C 34 _H 68 _{O 2,} molecular weight is 509. Glycerol trioleate has a molecular formula of C ₅₇ H ₁₀₄ O ₆ and a molecular weight of 885. The fatty acid ester is preferably selected from those having a molecular weight of 500 or more, and more preferably a fatty acid ester having a molecular weight of 600 or more.

  The incense stick substrate 2 includes at least a combustible combustion material such as wood flour, paper, and pulp, and a binder such as corn starch for solidifying the combustion material. The incense stick substrate 2 may contain a coloring agent or the like.

  The incense stick 1 is manufactured such that the concentration distribution of the volatile agent is not uniform in the depth direction of the incense stick substrate 2. That is, the base outer layer portion 2a having a thickness T2 that is 1/16 of the total thickness T1 of the incense base 2 contains 30% or more of the volatile agent contained in the entire incense base 2. The base material outer layer portion 2a is a portion between the outer surface of the incense stick base material 2 and the broken line L1, and the entire surface (upper surface in FIG. 1), side surfaces, and back surface (lower surface in FIG. 1) of the incense base material 2 Are provided. A broken line L1 is shown to specify a range of a thickness of 1/16 of the total thickness T1 of the incense stick substrate 2, and is a frame-shaped line similar to the cross-sectional shape of the incense stick base material 2. The base material outer layer portion 2a preferably contains 50% or more of the volatile drug contained in the entire incense stick substrate 2, and 60% or more of the volatile drug contained in the whole incense stick substrate 2. More preferably, it is contained in the base material outer layer portion 2a. For example, when the total thickness T1 of the incense stick substrate 2 is 4 mm, the thickness T2 of 1/16 of the total thickness T1 is 0.25 mm, and thus the thickness of the base material outer layer portion 2a is 0.25 mm. In this case, the portion of the incense stick substrate 2 excluding the substrate outer layer portion 2a becomes the inner layer portion, and the inner layer portion contains the remainder of the volatile agent. In addition, T2 is preferably 0.3 mm or less, and more preferably 0.25 mm or less.

  In addition, the base outer layer portion 2b having a thickness T3 that is 1/8 of the total thickness T1 of the incense base 2 contains 50% or more of the volatile chemical contained in the entire incense base 2. You may. In this case, the base material outer layer portion 2b is a portion between the outer surface of the incense base material 2 and the broken line L2, and is provided over the entire surface, side surface, and back surface of the incense base material 2. The dashed line L2 is shown to specify a range of a thickness of 1/8 of the total thickness T1 of the incense stick substrate 2, is a frame-like line similar to the cross-sectional shape of the incense stick substrate 2, and is inside the broken line L1. It is located in. For example, when the total thickness T1 of the incense stick substrate 2 is 4 mm, the thickness T3 of 1/8 of the total thickness T1 is 0.5 mm, so the thickness of the base material outer layer 2b is 0.5 mm. In this case, a portion of the incense stick substrate 2 excluding the substrate outer layer portion 2b becomes an inner layer portion, and this inner layer portion contains the remainder of the volatile agent.

  The volatile agent may be impregnated into only one of the front surface and the back surface of the incense stick substrate 2, or may be impregnated into both the front surface and the back surface of the incense stick substrate 2. Moreover, you may make it impregnate a volatile chemical | medical agent into a front surface side, a back surface side, and a side surface.

(Method of manufacturing incense stick 1)
Next, a method of manufacturing the incense stick 1 configured as described above will be described. First, an incense stick base material 2 and a stock solution to be applied to the incense stick base material 2 are prepared. The coating stock solution contains the volatile agent, the fatty acid ester, and a solvent. Examples of the solvent include normal paraffin such as parazol 134, hexane, ethanol, water and the like, and any one or a plurality of them may be used in combination. The amount of the volatile agent can be set to, for example, about 3.75 mg per incense stick 1, but is not limited to this, and can be set arbitrarily in consideration of the efficacy.

  Then, the undiluted solution is applied to the incense base material 2 prepared in advance, and the chemical contained in the entire incense base material 2 is applied to the base material outer layer 2 a having a thickness of 1/16 of the total thickness of the incense base material 2. 30% or more. This can be realized by the type of the solvent, the degree of dilution of the drug depending on the amount of the solvent, and the like.

  Further, the undiluted solution is applied to a previously prepared incense substrate 2, and the chemical contained in the entire incense substrate 2 is coated on the substrate outer layer 2 b having a thickness of １ ／ of the total thickness of the incense substrate 2. May be included. This can also be realized by the degree of dilution of the drug depending on the type of the solvent and the amount of the solvent.

  The undiluted coating solution is obtained by mixing each fatty acid ester and a solvent at a ratio of 1: 1 and adding a small amount of dimefultrine (0.52% w / w).

  Table 1 shows the effective transpiration rates of Comparative Examples 1 to 3 and Examples 1 to 3. “Effective transpiration rate (%)” in Table 1 indicates that when incense stick 1 was burned, the amount of dimefluthrin (volatile agent) contained in the incense stick 1 was volatilized in a state in which the effect was effective. Is a value that indicates If the effective transpiration rate is 100%, all of the dimefurthrin contained in the incense stick 1 is volatilized in a state in which it is effective. Conversely, if the effective transpiration rate is 0%, the dimefurthrin contained in the incense stick 1 is removed. Everything did not work. As a measuring method, for example, all the gas discharged by burning the incense stick 1 is collected, and the amount of dimefluthrin is measured using a measuring instrument such as gas chromatography. Then, the ratio of the amount of recovered dimefluthrin to the amount of dimefurthrin contained in the burned portion of the incense stick 1 is determined, and this can be used as the effective transpiration rate.

  Comparative Example 1 is an incense stick obtained by a kneading method. The “kneading production method” in Table 1 is a production method in which 3.75 mg of dimefurthrin as a volatile agent is kneaded into wood flour or a binder constituting an incense stick substrate, and then solidified to obtain an incense. The amount of wood flour into which 3.75 mg of dimefurthrin is kneaded is the amount of one common spiral incense stick. In the case of the incense stick obtained by this kneading method, the concentration of dimefurthrin becomes substantially uniform in the depth direction. In the inner layer portion, there is an amount obtained by subtracting the drug amount of the base material outer layer portion 2b from the total drug amount (3.75 mg). The dose can be expressed in wt%.

Comparative Examples 2, 3 and Examples 1 to 3 are applied incense sticks obtained by applying the stock solution to the incense stick substrate 2. Comparative Example 2 is a coated incense stick obtained by dissolving 3.75 mg of dimefurthrin in n-paraffin (normal paraffin) as a solvent to obtain a coating stock solution, and then applying the coating stock solution to the incense substrate 2. As the n-paraffin, for example, parazol 134 can be used, and the same applies to the following examples. Comparative Example 3 is a coated incense stick obtained by dissolving 3.75 mg of dimefurthrin and butyl stearate in n-paraffin as a solvent to obtain a coating stock solution, and then applying the coating stock solution to the incense substrate 2. Butyl stearate has a molecular formula of C ₂₂ H ₄₄ O ₂ and a molecular weight of 341.

  In Example 1, 3.75 mg of dimefurthrin, 3-isoamyl-6-methyl-2-heptyl stearate, and n-paraffin as a solvent were mixed to obtain an undiluted coating solution. 2 is an applied incense stick applied to No. 2.

  In Example 2, after applying 3.75 mg of dimethylfurthrin, 2-hexyldecyl isostearate, and n-paraffin as a solvent to obtain a coating solution, the coating solution was applied to the incense base 2 with the coating solution. is there.

  Example 3 is a coated incense stick obtained by mixing 3.75 mg of dimefluthrin, glycerol trioleate, and n-paraffin as a solvent to obtain a coating stock solution, and then applying the coating stock solution to the incense substrate 2.

  The effective transpiration rate of the kneading process of Comparative Example 1 was 70%, the effective transpiration rate when n-paraffin of Comparative Example 2 was used as a solvent was 79%, and the fatty acid ester having a molecular weight of less than 400 using n-paraffin of Comparative Example 3 as a solvent. The effective transpiration rate in the case of containing was 80%. On the other hand, when n-paraffins of Examples 1 to 3 were used as solvents and fatty acid esters having a molecular weight of 400 or more were contained, the effective transpiration rate was a high value of 88% to 94%. The solvent may be water, ethanol, or hexane, and any solvent can obtain a higher effective transpiration rate than Comparative Examples 1 to 3 by including a fatty acid ester having a molecular weight of 400 or more. it can.

  Further, in Examples 1 to 3 in Table 1, 30% or more of the drug contained in the entire incense stick substrate 2 is contained in the base material outer layer portion 2a, or the entire incense stick substrate 2 is contained in the base material outer layer portion 2b. The following shows a specific method for containing 50% or more of the drug contained in the above and the results thereof.

  In addition, when calculating | requiring the quantity of the volatile chemical | medical agent contained in the base material outer layer parts 2a and 2b, it corresponds to the thickness of the base material outer layer parts 2a and 2b while measuring the thickness of a base material with a caliper first. The amount is cut off, and the amount of the drug contained in the cut off portion is measured using gas chromatography. The amount of the drug contained in a portion (inner layer portion) other than the substrate outer layer portions 2a and 2b is also measured.

(Repelling test)
Next, the repellent test will be described. As shown in FIG. 2, a constant temperature test chamber 100 is prepared. The size of the test room 100 is about 8 tatami. The room temperature of the test room 100 is 28 ° C. The test room 100 is provided with two air intake windows 101 for taking in air into the test room 100 and one air discharge window 102 for discharging air from the test room 100. . The inflow and outflow of air were set so that the ventilation of the test room 100 was 10 times per hour. The test agent is incense stick 1. The test insects 104 were adult female Aedes mosquitoes (Jakarta D strain), and 50 were prepared in containers. The attraction source was human 103. The test method is a Free Fly, 0 start, human decoy method.

  First, as shown in FIG. 2, a test insect 104 was placed at one corner of the test room 100, and an incense stick 1 as a test agent was installed near the floor of the test room 100 and near the center of the test room 100. In addition, a human 103 serving as an attracting source was placed in a corner of the test room 100 where the test insect 104 was installed and a diagonal corner.

  Then, simultaneously with the ignition of the incense stick 1, the lid of the container containing the 50 test insects was gently opened, and the test insects were released into the test chamber 100. The number of blood sucking and flying to humans was recorded over time until one hour after the test insects were released (treatment chamber blood sucking number). Similarly, in a test room (not shown) having no incense stick (untreated room), 50 test insects were released, and the number of blood sucking flying to humans was recorded (untreated room blood sucking number). The blood sucking inhibition rate is calculated from the following equation.

Blood sucking inhibition rate (%) = (CT) / C × 100
C: Blood count in the non-treatment room T: Blood count in the treatment room

  The “repellent rate” in Table 2 refers to the above-mentioned blood sucking inhibition rate. “Efficacy ratio” in Table 2 is a relative ratio when the repellency of Comparative Example 1 is set to 100. As shown in Table 2, the efficacy ratio was 100 in Comparative Example 1 and 108 in Comparative Example 2, whereas the efficacy ratio was 116 in Example 2 and 118 in Example 3. Was. Although not shown in Table 2, based on the results in Table 1, Example 1 also has a significantly higher efficacy ratio.

(Operation and Effect of Embodiment)
As described above, according to this embodiment, the incense stick 1 in which the volatile incense is included in the incense stick base 2 contains the fatty acid ester having a molecular weight of 400 or more, so that the incense stick 1 is burned when the incense stick 1 is burned. Is easily volatilized, the effective transpiration rate of the drug is improved, and the efficacy of the drug can be increased.

  Further, in the above embodiment, the case where the volatile drug is dimefluthrin was described, but the same result is obtained even when the volatile drug is a pyrethroid-based compound such as transfluthrin and allethrin. When the volatile agent is a fragrance, the effect of the fragrance can be enhanced.

(Other embodiments)
The embodiments described above are merely examples in every respect and should not be construed as limiting. Further, all modifications and changes belonging to the equivalent scope of the claims are within the scope of the present invention.

  In the above embodiment, the incense stick 1 according to the embodiment of the present invention is obtained by applying the undiluted coating solution to the incense stick substrate. However, the present invention is not limited to this, and a fatty acid ester having a molecular weight of 400 or more and a volatile agent Is kneaded into wood flour or a binder that constitutes the incense base, and then solidified to obtain the incense stick 1 according to the embodiment of the present invention. Also in this case, the incense stick 1 containing a fatty acid ester having a molecular weight of 400 or more can be obtained, so that the same operation and effect as the applied incense stick can be obtained.

  As described above, the present invention can be used, for example, for insecticide incense sticks and aromatic incense sticks.

REFERENCE SIGNS LIST 1 incense stick 2 incense stick base material 2a base material outer layer part 2b base material outer layer part

Claims (4)

In incense sticks containing at least one of dimefluthrin, transfluthrin and allethrin as volatile agents in the incense base,
Stearic acid 3 isoamyl-6-methyl-2-heptyl as fatty acid esters, of isostearic acid 2-hexyl decyl and glycerol trioleate, it contains at least one,
An incense stick characterized in that 30% or more of the volatile agent contained in the entire incense stick base material is contained in a base material outer layer having a thickness of 1/16 of the total thickness of the incense stick base material . The incense stick according to claim 1 ,
The incense stick, wherein the fatty acid ester and the volatile agent are applied to the incense base material. In a method for manufacturing an incense stick containing at least one of dimefluthrin, transfluthrin and allethrin as a volatile agent in the incense stick base,
The resulting stearic acid 3 isoamyl-6-methyl-2-heptyl as fatty acid esters, of isostearic acid 2-hexyl decyl and glycerol trioleate, the coating stock solution by mixing at least one and a said volatile agent Then, by applying the undiluted coating solution to the incense stick substrate, the base material outer layer having a thickness of 1/16 of the total thickness of the incense stick substrate, the volatility contained in the entire incense stick substrate A method for producing an incense stick , comprising 30% or more of a drug . The method for producing an incense stick according to claim 3 ,
The method for producing incense sticks, wherein the coating stock solution contains normal paraffin as a solvent.

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