JP6559951B2 - Automatic analyzer - Google Patents

Description

  Embodiments of the present invention relate to an automatic analyzer that chemically analyzes a sample by reacting a sample such as blood and urine of a subject with a reagent, for example.

  The automatic analyzer can automatically add a reagent container to the reagent storage under analysis in order to reduce the work burden on the operator (automatic reagent loading). As a method of arranging the reagent containers in the reagent store, there are methods such as arranging them in order in a vacant area in the reagent store or arranging them evenly.

  However, for example, there are cases where the reagent container is covered with a lid after the measurement, such as an expensive reagent and a reagent that deteriorates when placed in the reagent storage for a long period of time. When reagent containers containing such reagents are scattered in the reagent store, a search operation and a removal operation of the reagent containers are required. For this reason, there is a problem that the work burden is large for the operator.

  In addition, there is a problem in that air contami- nation (Air Contamination) occurs in which the evaporated gas of the reagent contained in the reagent container affects the reagent contained in another adjacent reagent container through air. For this reason, there is a problem that an error occurs in the measurement result.

JP 2003-262642 A

  An object of the present embodiment is to provide an automatic analyzer capable of optimizing the arrangement of reagent containers according to the reagent to be accommodated.

According to the embodiment, the automatic analyzer includes a storage unit for storing group information relating to a plurality of groups classified the reagent according to a plurality of types of reagents each attribute information, the previous SL reagent reagent containers to yield capacity A reagent container having a plurality of regions corresponding to the plurality of groups, the group information, and the attribute information of the unarranged reagent stored in the unarranged reagent container. Based on the identification unit that identifies the group to which the unarranged reagent belongs, and a transfer mechanism that moves the unarranged reagent container to an area corresponding to the identified group, the transfer mechanism, the reagent storage is first attempt for accommodating a second reagent that is affected by the first reagent and air Tamil Nation causing air conditioning Tami Nation respectively The container and the second reagent container, is controlled to maintain at a one or more separate reagent containers, or empty container of the reagent container size.

The block diagram which shows an example of the automatic analyzer which concerns on embodiment. The perspective view which shows the external appearance of the reaction mechanism shown in FIG. The block diagram which shows an example of the reagent replenishment part shown in FIG. 1 and FIG. The perspective view which shows an example of the unarranged reagent container thrown into the reagent container insertion part shown in FIG. The figure which shows an example of the group information memorize | stored in the memory | storage part shown in FIG. The figure which shows an example of the air-conditioner terminal information memorize | stored in the memory | storage part shown in FIG. The figure which shows an example of the transfer form of the non-arranged reagent container by the transfer mechanism shown in FIG. The flowchart which shows an example of the transfer procedure of the unarranged reagent container in the reagent replenishment part shown in FIG. The figure which shows an example of the arrangement | positioning form of the reagent container arrange | positioned by the transfer procedure shown in FIG. The flowchart which shows an example of the transfer procedure of the unarranged reagent container in the reagent replenishment part 380 shown in FIG. 3 which considered the air conditioner of the reagent in a group. The figure which shows an example of the arrangement | positioning form of the reagent container arrange | positioned by the transfer procedure shown in FIG. The flowchart which shows the transfer procedure of the unarranged reagent container in the reagent replenishment part shown in FIG. 3 which considered the air-conditioner damage of the reagent between groups. The figure which shows an example of the arrangement | positioning form of the reagent container arrange | positioned by the transfer procedure shown in FIG.

  Hereinafter, an automatic analyzer according to an embodiment will be described with reference to the drawings. In the following description, components having substantially the same function and configuration are denoted by the same reference numerals, and redundant description will be given only when necessary.

  FIG. 1 is a diagram illustrating an example of an automatic analyzer 100 according to the embodiment. As shown in FIG. 1, the automatic analyzer 100 includes a reaction mechanism 10, an analysis unit 50, an output unit 60, an input unit 70, a system control unit 80, and an interface (hereinafter referred to as I / F) 90.

  FIG. 2 is a perspective view showing the appearance of the reaction mechanism 10. The reaction mechanism 10 includes a sampler unit 34, a sample probe 334, a sample arm 336, a first reagent store 350, a second reagent store 370, a reagent replenishment unit 380, a first reagent probe 354, a first reagent arm 356, and a second reagent probe. 374, a second reagent arm 376, a stirring unit 320, a washing unit 325, a reaction vessel support unit 310, a photometry unit 32, and the like.

  The sampler unit 34 moves the sample rack 340 containing a plurality of sample containers to a position (hereinafter referred to as a sample suction position) for sucking a sample in the sample container. The sample rack 340 holds a plurality of sample containers 3400. Hereinafter, the sample rack will be described as holding five sample containers. The sampler unit 34 includes a tray 341, a rack pull-in device 343, a rack lateral movement device 345, and a rack push-out device 347.

  A plurality of sample racks 340 are placed in parallel on the tray 341 along a first direction 349 that is the longitudinal direction of the tray. The tray 341 moves the plurality of sample racks 340 placed along the first direction 349. Each of the rack pull-in device 343, the rack lateral movement device 345, and the rack push-out device 347 has a motor for moving the sample rack 340. The rack pull-in device 343 pulls the sample rack at the pull-in point 202 from the tray 341 into the rack pull-in lane 200 along the second direction 201 under the control of the reaction mechanism control unit 36. The rack lateral movement device 345 laterally moves the sample rack 3401 located in the rack pull-in lane 200 to the sampling lane 204 along the first direction 349. The rack pusher 347 moves the sample rack 3402 in the sampling lane 204 to the sample suction position along the direction opposite to the second direction 201. In the present embodiment, the sampler unit 34 has been described as a rack sampler, but may be a disk sampler.

  The sample probe 334 is attached to the tip of the sample arm 336. The sample arm 336 supports the sample probe 334 so as to be rotatable. The sample probe 334 sucks a sample from a sample container at a sample suction position on the sampling lane 204 by a sample dispensing pump. The sample probe 334 discharges the sucked sample to the reaction container 312 at the position where the sample is discharged at the position where the sample is discharged at the reaction container support part 310.

  The first reagent storage 350 holds a plurality of first reagent containers 352 corresponding to a plurality of measurement items. The second reagent store 370 holds a plurality of second reagent containers 372 corresponding to a plurality of measurement items. The first reagent container 352 and the second reagent container 372 contain reagents that react with the components of each test item. The first reagent store 350 and the second reagent store 370 rotate at a predetermined angle at a predetermined timing under the control of the reaction mechanism control unit 36. The reaction mechanism 10 may further include other reagent containers in addition to the first reagent container 350 and the second reagent container 370. The first reagent container 350 and the second reagent container 370 keep the plurality of retained reagent containers cold. The first reagent store 350 and the second reagent store 370 have holding sections for holding each of the plurality of reagent containers.

  Moreover, the 1st reagent store 350 and the 2nd reagent store 370 have a some area | region each corresponding to the some group which classified the reagent according to the attribute information of each of a plurality of types of reagent. The first reagent store 350 and the second reagent store 370 hold a plurality of reagent containers that store a plurality of reagents belonging to each group for each region. For example, an area number is assigned to each of the plurality of areas (numbering). The user changes the area for holding the plurality of first reagent containers 352 in the first reagent container 350 and the plurality of second reagent containers 372 in the second reagent container 370 by changing the area number corresponding to each group. Is possible. Note that the number of the regions may be the same or different for each of the first reagent store 350 and the second reagent store 370.

  Here, the first reagent store 350 and the second reagent store 370 may continuously arrange the reagent containers in the region.

  Further, the first reagent storage 350 and the second reagent storage 370 hold the reagent containers with a predetermined interval between the group and the group adjacent to the group in order to further arrange the reagent containers. May be. Further, in the first reagent container 350 and the second reagent container 370, in order to reduce the positional deviation of the plurality of reagent containers held in the reagent container, the arrangement of the plurality of reagent containers and the plurality of reagent containers are held. At least one of the areas to be performed may be changed as appropriate.

  Moreover, the 1st reagent storage 350 and the 2nd reagent storage 370 may hold | maintain the several reagent container which accommodates the several reagent regarding an air-conditioner at predetermined intervals. The air conditioner means, for example, that the evaporated gas of the reagent stored in the reagent container affects the reagent stored in another adjacent reagent container through air.

  For example, when holding a plurality of reagent containers for storing a plurality of reagents related to air-conditioning in at least one of the above regions, the first reagent container 350 and the second reagent container 370 have a plurality of predetermined intervals. A reagent container may be held.

  In addition, the first reagent container 350 and the second reagent container 370 hold a plurality of reagent containers for storing a plurality of reagents related to air conditioner in a region and a region different from the region, with a predetermined interval. A plurality of reagent containers may be held respectively. For example, the first reagent store 350 and the second reagent store 370 may hold a plurality of reagent containers that store a plurality of reagents related to the air conditioner with at least one region therebetween.

  The reagent replenishing unit 380 replenishes the first reagent container 352 held in the first reagent container 350. The reagent replenishing unit 380 replenishes the second reagent container 372 held in the second reagent storage 370. The reagent replenishing unit 380 may be provided in each of the first reagent container 350 and the second reagent container. The configuration of the reagent replenishing unit 380 will be described in detail later.

  The first reagent probe 354 is attached to the tip of the first reagent arm 356. The first reagent arm 356 supports the first reagent probe 354 so as to be rotatable and vertically movable. The first reagent probe 354 descends from the standby position into the first reagent container 352 at the position where the first reagent is aspirated on the first reagent storage 350. The first reagent probe 354 sucks the first reagent from the first reagent container 352 by a predetermined amount by the first reagent dispensing pump. The first reagent probe 354 moves up to the standby position after completing a predetermined amount of suction. The first reagent probe 354 discharges the aspirated first reagent into the reaction container 312 at the position where the first reagent is discharged in the reaction container support part 310.

  The second reagent probe 374 is attached to the tip of the second reagent arm 376. The second reagent arm 376 supports the second reagent probe 374 so as to be rotatable and vertically movable. The second reagent probe 374 descends from the standby position into the second reagent container 372 at the position for aspirating the second reagent on the second reagent storage 370. The second reagent probe 374 sucks the second reagent from the second reagent container 372 by a predetermined amount by the second reagent dispensing pump. The second reagent probe 374 moves up to the standby position after completing a predetermined amount of suction. The second reagent probe 374 discharges the aspirated second reagent to the reaction container 312 at the position where the second reagent is discharged in the reaction container support part 310.

  The stirring unit 320 includes a stirring arm 322 and a stirring bar 324. The stirring bar 324 is attached to the tip of the stirring arm 322. The stirring arm 322 supports the stirring bar 324 so as to be rotatable and vertically movable. The stirring arm 322 inserts the stirring bar 324 from the standby position into the reaction container 312 stopped at the position where the test mixture in the reaction container 312 is stirred. When the tip of the stirring bar 324 is lowered to the vicinity of the inner bottom surface of the reaction vessel 312, the stirring arm 322 stops the lowering of the stirring bar 324. After the stirring bar 324 is stopped, the stirring bar 324 vibrates under the control of the reaction mechanism control unit 36. As the stirrer 324 vibrates, the liquid mixture (sample and first reagent, sample and second reagent, sample, first reagent and second reagent, etc.) in the reaction vessel 312 is stirred. After stirring, the stirring arm 322 raises the stirring bar 324 to the standby position.

  The cleaning unit 325 includes a support mechanism (not shown), a cleaning nozzle, and a drying nozzle. The support mechanism supports the cleaning nozzle and the drying nozzle so as to be movable up and down, respectively. The washing nozzle sucks the mixed solution from the reaction vessel 312 at the position for washing the reaction vessel 312 on the reaction vessel support 310 by a washing pump. After sucking the mixed solution, the cleaning nozzle discharges pure water to clean the inside of the reaction vessel 312. The drying nozzle dries the inside of the reaction vessel 312 in the position for drying the reaction vessel 312 on the reaction vessel support part 310 with a drying pump.

  The reaction vessel support unit 310 rotatably supports a plurality of reaction vessels 312 arranged on the circumference. The reaction vessel 312 is accommodated in a thermostatic bath. The reaction vessel support unit 310 stops after rotating at a predetermined angle for each analysis cycle. Thereby, the reaction vessel 312 is rotated by a predetermined angle.

  The photometric unit 32 irradiates a mixture of a test sample and a reagent (hereinafter referred to as a test mixture) with light. The photometry unit 32 converts the light transmitted through the test mixture into absorbance, and generates absorbance data regarding the test sample. The photometry unit 32 outputs the generated absorbance data to the data storage unit 52. The photometric unit 32 irradiates a mixture of a standard substance and a reagent (hereinafter referred to as a standard mixture) with light. The standard substance is a substance having the same or common property as the substance to be measured or a substance having a common reaction with a reagent. The photometry unit 32 converts light that has passed through the standard mixture into absorbance, and generates absorbance data relating to the standard substance. The photometry unit 32 outputs absorbance data regarding the standard substance to the data storage unit 52.

  The reaction mechanism control unit 36 applies to each element of the reaction mechanism 10 shown in FIG. 2 based on signals from the system control unit 80 regarding analysis items, analysis procedures, and the like input by the operator via the input unit 70. Create a sequence. The reaction mechanism control unit 36 rotates the first reagent container 350 and the second reagent container 370 at a predetermined angle at a predetermined timing based on the assembled sequence.

  Based on the assembled sequence, the reaction mechanism control unit 36 connects the plurality of sample racks 340 arranged in the tray 341 shown in FIG. 2 to the rack pull-in lane 200 along the first direction 349 (hereinafter, referred to as “reaction mechanism”). , The operation of the tray 341 is controlled. The reaction mechanism control unit 36 controls the rack pull-in device 343 to move the sample rack at the pull-in point 202 to the rack pull-in lane 200 along the second direction 201 based on the assembled sequence. The reaction mechanism controller 36 controls the rack lateral movement device 345 to laterally move the sample rack 3401 in the rack pull-in lane 200 to the sampling lane 204 along the first direction 349 based on the assembled sequence. To do. Based on the assembled sequence, the reaction mechanism control unit 36 controls the rack pusher 347 to pitch the sample rack that has been laterally moved on the sampling lane 204 along the direction opposite to the second direction 201. To do. Specifically, the reaction mechanism control unit 36 controls the rack pusher 347 in order to move the sample container to be sampled to the sample suction position.

  The reaction mechanism control unit 36 rotates and vertically moves the sample probe 334, the first reagent probe 354, and the second reagent probe 374 shown in FIG. 2 based on the assembled sequence. The reaction mechanism control unit 36 moves the stirrer 324 and the cleaning nozzle and the drying nozzle of the cleaning unit 325 shown in FIG. 2 up and down based on the assembled sequence. The reaction mechanism control unit 36 drives a sample dispensing pump, a first reagent dispensing pump, a second reagent dispensing pump, a washing pump, and a drying pump, which are not shown, based on the assembled sequence. The reaction mechanism control unit 36 vibrates the stirring bar 324 shown in FIG. 2 based on the assembled sequence.

  The reaction mechanism control unit 36 controls the transfer mechanism 3811 based on the arrangement information of the reagent containers in the reagent store (the first reagent store 350 and the second reagent store 370) and the specified result by the specifying unit 387 described later. Specifically, under the control of the reaction mechanism control unit 36, the transfer mechanism 3811 relates to the group to which the unarranged reagent specified in the reagent storage belongs to the unarranged reagent container that has been input to the reagent container input unit 381. Transport to area.

  The analysis unit 50 includes a sample analysis unit 51 and a data storage unit 52. The sample analysis unit 51 generates calibration curve data based on the absorbance data and analysis items stored in the data storage unit 52. The generated calibration curve data is stored in the data storage unit 52 and output to the output unit 60. Based on the calibration curve data and the absorbance data regarding the test sample stored in the data storage unit 52, the sample analysis unit 51 generates analysis data regarding the concentration and activity value of the component corresponding to the test item. . The generated analysis data is stored in the data storage unit 52 and output to the output unit 60.

  The data storage unit 52 includes a storage medium such as a hard disk. The data storage unit 52 stores absorbance data generated by the photometry unit 32 of the reaction mechanism 10. The data storage unit 52 stores the calibration curve data generated by the sample analysis unit 51 for each standard substance. The data storage unit 52 stores the analysis data generated by the sample analysis unit 51 for each test sample.

  The input unit 70 includes input devices such as a keyboard, a mouse, various buttons, and a touch key panel. The input unit 70 outputs the analysis conditions of each measurement item input by the operator via the input device, the measurement items measured for each test sample, and the like to the system control unit 80 as operation signals. Information input by the operator via the input unit 70 may be stored in a storage unit (not shown).

  The system control unit 80 has a CPU (Central Processing Unit). The system control unit 80 controls each unit in the automatic analyzer 100 in an integrated manner. The system control unit 80 controls each unit based on an operation signal supplied from the input unit 70. For example, the system control unit 80 controls the reagent storage unit 360 that will be described later.

  For example, a network is connected to the I / F 90. The automatic analyzer 100 may be connected to a PACS (Picture Archiving and Communication System) or the like via a network.

  FIG. 3 is a block diagram illustrating an example of the reagent replenishing unit 380 illustrated in FIGS. 1 and 2.

  As shown in FIG. 3, the reagent replenishing unit 380 includes a reagent container inserting unit 381, a reagent container detecting unit 383, a code reading unit 385, a specifying unit 387, a storage unit 389, and a transfer mechanism 3811.

  The reagent container loading unit 381 has a plurality of loading sections for loading unarranged reagent containers. The reagent container detection unit 383 detects a non-arranged reagent container that has been input to the input section. The reagent container loading unit 381 is replenished to the first reagent container 350 and the second reagent container 370 (hereinafter, when the first reagent container 350 and the second reagent container 370 are not distinguished, they are simply referred to as reagent containers). At least one unplaced reagent container is retained.

  FIG. 4 is a perspective view illustrating an example of an unplaced reagent container that is loaded into the reagent container loading unit 381 illustrated in FIG. 3. As shown in FIG. 4, on the outer surface of the unplaced reagent container, the measurement item name, the reagent container size, the reagent type, the reagent lot number, the reagent usage frequency, the transfer destination reagent storage, and the reagent expiration date A one-dimensional code (bar code) or a two-dimensional code (stacked two-dimensional code, matrix-type two-dimensional code, etc.) having information (hereinafter referred to as attribute information) such as a reagent is provided. Note that a storage medium such as an IC (Integrated Circuit) tag may be provided on the outer surface of the reagent container 352 instead of the one-dimensional code or the two-dimensional code. Further, the attribute information may include information related to the price of the reagent, reagent deterioration, reagent volatilization (evaporation), air conditioner damage, and the like.

  In addition, the reagent container and the unplaced reagent container are containers having the same shape. The reagent container and the unplaced reagent container may be containers having different shapes.

  Hereinafter, for convenience of explanation, it is assumed that the barcode 353 is attached to the unplaced reagent container. The attribute information includes the measurement item name, reagent container size, reagent type, reagent lot number, reagent usage frequency, destination reagent storage, reagent expiration date, reagent price, reagent deterioration, reagent Information on reagents such as volatilization (evaporation) and air conditioning damage may be included.

  The code reading unit 385 includes at least one of a bar code reader (BCR), a reader that reads a two-dimensional code, and a reader that reads attribute information from a storage medium such as an IC tag. The code reading unit 385 acquires attribute information from the barcode provided in the unplaced reagent container via the BCR. The code reading unit 385 outputs the attribute information acquired by the BCR to the specifying unit 387 described later.

  The storage unit 389 stores group information related to a plurality of groups in which reagents are classified according to attribute information of each of a plurality of types of reagents. FIG. 5 is a diagram illustrating an example of group information stored in the storage unit 389 illustrated in FIG. As illustrated in FIG. 5, the storage unit 389 stores, for example, a group name, a comment characterizing each group, a name of a reagent belonging to each group, and an area number related to an area holding the reagent container. doing. The area number is associated with the area number of each area shown in FIG.

  The group information may be updated according to new reagent information, test order, and the like. For example, the group information may be updated according to a user instruction via the input unit 70. Further, the group information may be updated by predetermined update information acquired via the network.

  In addition, in the update of group information, the area number corresponding to each group may be changed. Thereby, it is possible to change the area | region which hold | maintains the several reagent container in a reagent store | warehouse | chamber.

  In addition, the storage unit 389 stores air conditioner information related to the air conditioner between the reagents stored in the reagent storage. FIG. 6 is a diagram showing an example of air conditioner information stored in the storage unit 389 shown in FIG. As illustrated in FIG. 6, the storage unit 389 stores, for example, a reagent name (RGT-X) and a reagent name (RGT-Y) that is affected by air-conditioning damage from the reagent.

  Note that the air conditioner information may be updated in accordance with new reagent information and test orders. For example, the air conditioner information may be updated by the user. Further, the air conditioner information may be updated via the network.

  Based on the attribute information of the unarranged reagent stored in the unarranged reagent container acquired by the BCR and the group information stored in the storage unit 389, the specifying unit 387 includes the group to which the unarranged reagent belongs. Is identified.

  FIG. 7 is a diagram illustrating an example of a transfer form of unplaced reagent containers by the transfer mechanism 3811 shown in FIG. As shown in FIG. 7, the transfer mechanism 3811 has a pickup arm for transferring the non-arranged reagent container that has been input to the reagent container input unit 381. Note that the transfer mechanism 3811 can use means other than the pickup arm as means for transferring the unplaced reagent container.

  Specifically, when the unplaced reagent container put into the reagent container throwing section 381 is detected by the reagent container detecting section 383, the transfer mechanism 3811 moves the detected unplaced reagent container to the BCR of the code reading section 385. Move to the vicinity. When the barcode attached to the detected unarranged reagent container is read by the BCR, the transfer mechanism 3811 transfers the detected unarranged reagent container to the inserted reagent container input unit 381.

  The transfer mechanism 3811 transfers the unplaced reagent container that stores the unplaced reagent to the area related to the group to which the unplaced reagent identified by the identifying unit 387 belongs. For example, the transfer mechanism 3811 transfers the non-arranged reagent containers in the input section to the region corresponding to the specified group based on the arrangement information of the reagent containers in the reagent storage and the specifying result by the specifying unit 387.

  Note that the transfer mechanism 3811 may transfer a non-arranged reagent container to the reagent warehouse with a predetermined interval between the group and a group adjacent to the group in order to appropriately arrange the reagent container. Good.

  Further, the transfer mechanism 3811 may transfer the non-arranged reagent containers to the reagent storage so that the plurality of reagent containers that store the plurality of reagents related to the air conditioner are arranged at a predetermined interval. For example, when a plurality of reagent containers (hereinafter referred to as air conditioner containers) that store a plurality of reagents related to air conditioner are arranged in at least one of the above regions, the air conditioner container and the unplaced reagent containers are The transfer mechanism 3811 may transfer a non-placed reagent container to the reagent storage in order to place the gap in the region with an interval.

  In addition, when the air conditioner container is arranged in two different regions with a predetermined interval, the transfer mechanism 3811 may remove the unarranged reagent container in order to separate the air conditioner container and the unarranged reagent container by a predetermined interval. You may transfer to a reagent storage. For example, the transfer mechanism 3811 may transfer the unplaced reagent container to the reagent storage across at least one region.

  Here, the arrangement of the unplaced reagent containers in the automatic analyzer 100 according to the embodiment will be described with a specific example.

  FIG. 8 is a flowchart showing an example of a procedure for transferring unplaced reagent containers in the reagent replenishing unit 380 shown in FIG.

  As shown in FIG. 8, when an unplaced reagent container is placed in the reagent container placing portion 381, the placed unplaced reagent container is detected (step ST11).

  The unplaced reagent container is transferred to the vicinity of the BCR of the code reading unit 385 by the transfer mechanism 3811. The barcode 353 provided in the unplaced reagent container transferred to the vicinity of the BCR is read by the BCR. By reading the barcode with the BCR, the attribute information regarding the reagent of the input reagent container is acquired by the code reading unit 385 (step ST12).

  Based on the attribute information acquired by the code reading unit 385 and the group information stored in the storage unit 389, the group to which the unplaced reagent belongs is specified by the specifying unit 387 (step ST13).

  When the group to which the unarranged reagent belongs is identified by the identification unit 387, the unarranged reagent container in the input section is transferred to the area related to the identified group based on the identification result and arrangement information by the identification unit 387 ( Step ST14).

FIG. 9 is a diagram showing an example of an arrangement form of reagent containers arranged by the transfer procedure shown in FIG. As shown in FIG. 9, in the reagent store, a plurality of reagent containers for storing a plurality of reagents belonging to each group are held for each region. Reagent containers that store reagents belonging to group A are held in the area of area number # 1. Reagent containers that store reagents belonging to group B are held in the area of area number # 3. Reagent containers that store reagents belonging to group C are held in the area of area number # 2.

  Here, the reagent storage may hold the reagent containers with a predetermined interval between the group and a group adjacent to the group, assuming further arrangement of the reagent containers. For example, the reagent store may hold the reagent containers with a space area of at least one reagent container size between the group and a group adjacent to the group.

(Arrangement in consideration of air conditioning damage of reagents in the group)
FIG. 10 is a flowchart showing an example of a procedure for transferring unplaced reagent containers in the reagent replenishing unit 380 shown in FIG. 3 in consideration of the air conditioner of the reagent in the group. Note that a description of the same parts as those in FIG. 7 is omitted.

  The group to which the unarranged reagent belongs is specified by the specifying unit 387 (step ST13 in FIG. 8). Next, based on the identification result by the identification unit 387 and the arrangement information, the non-arranged reagent containers in the input section are transferred to the area related to the identified group. Specifically, when the air conditioner container is arranged at one end of the specified area, the non-arranged reagent container is transferred to the other end of the area based on the air conditioner information stored in the storage unit 389. (Step ST21). When the air conditioner container is held in the specified area, the non-arranged reagent container may be transferred from the air conditioner container to the specified area at a predetermined interval.

  FIG. 11 is a diagram showing an example of an arrangement form of reagent containers arranged by the transfer procedure shown in FIG. As shown in FIG. 11, the plurality of air conditioner containers in the same region of the reagent storage are respectively arranged at a predetermined interval. That is, the air conditioner container and the non-arranged reagent container are disposed at one end and the other end of the same region.

(Arrangement considering the air conditioner of reagents between groups)
FIG. 12 is a flowchart showing a procedure for transferring unplaced reagent containers in the reagent replenishing unit 380 shown in FIG. 3 in consideration of the air conditioner of the reagents between groups. Note that a description of the same parts as those in FIGS. 7 and 8 is omitted.

  The arrangement information of the air conditioner container is output from the reaction mechanism control unit 36 to the specifying unit 387 (step ST31). Next, the specifying unit 387 specifies the position of the transfer destination of the unplaced reagent container based on the arrangement information of the air conditioner container (step ST32). The position of the transfer destination is a position (diagonal position) facing the holding section where the air conditioner container is held across the rotation axis (center) of the reagent storage. The non-arranged reagent container in the input section is transferred to the diagonal position (step ST33).

  FIG. 13 is a diagram showing an example of an arrangement form of reagent containers arranged by the transfer procedure shown in FIG.

  As shown in FIG. 13, in the reagent store, the two reagent containers relating to the air conditioner are respectively arranged at positions facing each other across the rotation axis (center of the reagent store). For example, the air conditioner container and the non-arranged reagent container are arranged in a region corresponding to the region number # 2 provided on the diagonal line and a region corresponding to the region number # 3.

  According to the above configuration, the automatic analyzer 100 according to the embodiment includes a storage unit that stores group information related to a plurality of groups in which the reagents are classified according to attribute information of each of a plurality of types of reagents, group information, and unplaced Based on the attribute information of the unarranged reagent accommodated in the reagent container, a transfer unit that transfers the unarranged reagent container to a specific unit that identifies the group to which the unarranged reagent belongs, among the groups, and an area related to the specified group With. Thereby, in the reagent store, it is possible to hold a reagent container for storing the reagent for each of a plurality of regions corresponding to each group.

  Therefore, the automatic analyzer 100 according to the embodiment can reduce the burden of the removal operation of the reagent container by the operator.

  In addition, in consideration of the influence of air conditioning damage between reagents, the automatic analyzer 100 arranges reagent containers in the reagent storage so that reagents that cause air conditioning damage are not adjacent to each other. Thereby, it becomes possible to prevent deterioration of the reagent.

  Therefore, the automatic analyzer 100 according to the embodiment can obtain a highly reliable measurement result.

  As mentioned above, although embodiment of this invention was described, this embodiment is shown as an example and is not intending limiting the range of invention. The novel embodiment can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. This embodiment and its modifications are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

  DESCRIPTION OF SYMBOLS 1 ... Automatic analyzer, 10 ... Reaction mechanism, 32 ... Photometry part, 34 ... Sampler part, 36 ... Reaction mechanism control part, 50 ... Analysis part, 51 ... Sample analysis part, 52 ... Data storage part, 60 ... Output part, DESCRIPTION OF SYMBOLS 61 ... Printing part, 62 ... Display part, 70 ... Input part, 80 ... System control part, 90 ... Interface (I / F), 200 ... Rack pull-in lane, 201 ... 2nd direction, 202 ... Pull-in point, 204 ... Sampling lane, 310 ... reaction vessel support, 312 ... reaction vessel, 320 ... stirring unit, 322 ... stirring arm, 324 ... stirring bar, 325 ... washing unit, 330 ... detector, 331 ... irradiating unit, 333 ... light receiving unit, 334 ... Sample probe, 335 ... Sensor line, 336 ... Sample arm, 337 ... Cable, 340 ... Sample rack, 341 ... Tray, 343 ... Rack retracting device 345 ... Rack lateral movement device, 337 ... Rack extrusion device, 349 ... First direction, 350 ... First reagent storage, 352 ... First reagent container, 354 ... First reagent probe, 356 ... First reagent arm, 370 ... 2nd reagent storage, 372 ... 2nd reagent container, 374 ... 2nd reagent probe, 376 ... 2nd reagent arm, 3400 ... sample container, 3401 ... sample rack, 3402 ... sample rack, 380 ... reagent replenishing part, 381 ... reagent Container loading unit, 383... Reagent container detection unit, 385... Code reading unit, 387... Identification unit, 389.

Claims (5)

A storage unit that stores group information regarding a plurality of groups in which the reagents are classified according to attribute information of each of a plurality of types of reagents;
Holds in place the reagent container containing a pre-Symbol reagent on the circumference, a reagent storage having a plurality of regions corresponding to the plurality of groups,
Based on the group information and attribute information of the unarranged reagent stored in the unarranged reagent container, a specifying unit that identifies a group to which the unarranged reagent belongs among the plurality of groups,
A transfer mechanism for transferring the non-arranged reagent container in a region corresponding to the specified group;
The transfer mechanism, the reagent storage is a first reagent container and a second reagent container containing a second reagent that is affected by the first reagent and air Tamil Nation causing air conditioning Tami Nation respectively, An automatic analyzer that is controlled to hold one or more separate reagent containers or empty areas of reagent container size apart. The transfer mechanism, the reagent storage is at least one of the plurality of regions, to hold the pre-Symbol first reagent container and the second reagent container, before Symbol first reagent container and the second Two reagent containers are controlled to hold the one or more other reagent containers or an empty area of the reagent container size apart from each other.
The automatic analyzer according to claim 1. The transfer mechanism, the reagent storage is first in a second region different from the region and the first region, said the first region and the first reagent of the plurality of regions holding the container, said second region is controlled so as to hold the second reagent container,
The automatic analyzer according to claim 1. The transfer mechanism, the reagent storage is controlled to provide at least one region between said first region and said second region,
The automatic analyzer according to claim 3. The transfer mechanism, the reagent storage is the one or more separate reagent containers, or the free space of the reagent container size between the group and the predetermined group adjacent to the predetermined group of the plurality of groups It is controlled so as Ru provided,
The automatic analyzer according to any one of claims 1 to 4.

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