JP6557235B2 - de novo脂質生成のバイオマーカーおよびその使用方法 - Google Patents
de novo脂質生成のバイオマーカーおよびその使用方法 Download PDFInfo
- Publication number
- JP6557235B2 JP6557235B2 JP2016541152A JP2016541152A JP6557235B2 JP 6557235 B2 JP6557235 B2 JP 6557235B2 JP 2016541152 A JP2016541152 A JP 2016541152A JP 2016541152 A JP2016541152 A JP 2016541152A JP 6557235 B2 JP6557235 B2 JP 6557235B2
- Authority
- JP
- Japan
- Prior art keywords
- dnl
- levels
- biomarker
- level
- biomarkers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7057—(Intracellular) signaling and trafficking pathways
- G01N2800/7066—Metabolic pathways
- G01N2800/7085—Lipogenesis or lipolysis, e.g. fatty acid metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361918866P | 2013-12-20 | 2013-12-20 | |
| US61/918,866 | 2013-12-20 | ||
| US201461934033P | 2014-01-31 | 2014-01-31 | |
| US61/934,033 | 2014-01-31 | ||
| PCT/US2014/071035 WO2015095451A1 (en) | 2013-12-20 | 2014-12-18 | Biomakers of de novo lipogenesis and methods using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017500567A JP2017500567A (ja) | 2017-01-05 |
| JP2017500567A5 JP2017500567A5 (enExample) | 2018-02-01 |
| JP6557235B2 true JP6557235B2 (ja) | 2019-08-07 |
Family
ID=53403674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016541152A Active JP6557235B2 (ja) | 2013-12-20 | 2014-12-18 | de novo脂質生成のバイオマーカーおよびその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20160356798A1 (enExample) |
| EP (1) | EP3082833B1 (enExample) |
| JP (1) | JP6557235B2 (enExample) |
| AU (1) | AU2014364539B2 (enExample) |
| CA (1) | CA2933571A1 (enExample) |
| ES (1) | ES2708807T3 (enExample) |
| MX (1) | MX2016008045A (enExample) |
| SG (1) | SG11201604702YA (enExample) |
| WO (1) | WO2015095451A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105400732A (zh) * | 2015-11-19 | 2016-03-16 | 南京理工大学 | 一种酒精性脂肪肝斑马鱼模型的构建方法 |
| JP6992057B2 (ja) | 2016-06-10 | 2022-01-13 | クラリティ コスメティックス インコーポレイテッド | 非面皰形成性の毛髪および頭皮ケア製剤ならびにその使用方法 |
| GB201614455D0 (en) | 2016-08-24 | 2016-10-05 | Univ Oxford Innovation Ltd | Biomarkers |
| US11709169B2 (en) * | 2017-02-07 | 2023-07-25 | National Jewish Health | Lipid abnormalities and association with atopic allergic diseases |
| EP3602605A4 (en) * | 2017-03-31 | 2020-12-30 | Metabolon, Inc. | FULL AND QUANTITATIVE ANALYSIS OF LIPIDS AND TOCOPHEROLS |
| US11642300B2 (en) | 2019-05-15 | 2023-05-09 | Johnson & Johnson Consumer Inc. | Method of selecting skin treatment regimens, ingredients and compositions |
| US20220142560A1 (en) | 2020-11-06 | 2022-05-12 | Johnson & Johnson Consumer Inc. | Microbiome and metobolome clusters to evaluate skin health |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1438420B1 (en) * | 2001-09-24 | 2009-09-16 | Lipomics Technologies, Inc. | Methods of using quantitative lipid metabolome data |
| JP4682980B2 (ja) * | 2004-04-23 | 2011-05-11 | 味の素株式会社 | 非アルコール性脂肪肝炎鑑別方法 |
| US8119358B2 (en) * | 2005-10-11 | 2012-02-21 | Tethys Bioscience, Inc. | Diabetes-related biomarkers and methods of use thereof |
| CN102317786A (zh) * | 2007-04-18 | 2012-01-11 | 特提斯生物科学公司 | 糖尿病相关性生物学标记物及其使用方法 |
| WO2010028336A2 (en) * | 2008-09-08 | 2010-03-11 | President And Fellows Of Harvard College | Fatty acid c16:1n7-palmitoleate a lipokine and biomarker for metabolic status |
| WO2012040318A2 (en) * | 2010-09-23 | 2012-03-29 | University Of Miami | Compositions, methods and kits for detecting melanoma and margins of melanoma |
-
2014
- 2014-12-18 CA CA2933571A patent/CA2933571A1/en not_active Abandoned
- 2014-12-18 AU AU2014364539A patent/AU2014364539B2/en active Active
- 2014-12-18 WO PCT/US2014/071035 patent/WO2015095451A1/en not_active Ceased
- 2014-12-18 EP EP14870759.9A patent/EP3082833B1/en active Active
- 2014-12-18 JP JP2016541152A patent/JP6557235B2/ja active Active
- 2014-12-18 US US15/104,560 patent/US20160356798A1/en not_active Abandoned
- 2014-12-18 ES ES14870759T patent/ES2708807T3/es active Active
- 2014-12-18 MX MX2016008045A patent/MX2016008045A/es active IP Right Grant
- 2014-12-18 SG SG11201604702YA patent/SG11201604702YA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201604702YA (en) | 2016-07-28 |
| WO2015095451A1 (en) | 2015-06-25 |
| US20160356798A1 (en) | 2016-12-08 |
| CA2933571A1 (en) | 2015-06-25 |
| ES2708807T3 (es) | 2019-04-11 |
| JP2017500567A (ja) | 2017-01-05 |
| AU2014364539B2 (en) | 2019-08-01 |
| AU2014364539A1 (en) | 2016-06-16 |
| EP3082833B1 (en) | 2018-12-05 |
| EP3082833A1 (en) | 2016-10-26 |
| EP3082833A4 (en) | 2017-08-09 |
| MX2016008045A (es) | 2016-10-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6557235B2 (ja) | de novo脂質生成のバイオマーカーおよびその使用方法 | |
| Tsimikas et al. | C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients | |
| Steptoe et al. | Associations between acute lipid stress responses and fasting lipid levels 3 years later. | |
| Lee et al. | Association of serum proprotein convertase subtilisin/kexin type 9 with carotid intima media thickness in hypertensive subjects | |
| Ilias et al. | Adipose tissue lipolysis and circulating lipids in acute and subacute critical illness: effects of shock and treatment | |
| Kim et al. | Comparison of epicardial, abdominal and regional fat compartments in response to weight loss | |
| Mishra et al. | Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study | |
| JP6158186B2 (ja) | インスリン抵抗性に関連するバイオマーカーおよびそれを使用する方法 | |
| Chen et al. | The association of metabolic syndrome and its components with brachial-ankle pulse wave velocity in south China | |
| Li et al. | ABO blood group in relation to plasma lipids and proprotein convertase subtilisin/kexin type 9 | |
| US20150011424A1 (en) | Method for determining liver fat amount and method for diagnosing nafld | |
| Notarnicola et al. | Significant decrease of saturation index in erythrocytes membrane from subjects with non-alcoholic fatty liver disease (NAFLD) | |
| Gander et al. | Metabolic impairment in coronary artery disease: elevated serum acylcarnitines under the spotlights | |
| KR101598597B1 (ko) | 혈장 대사체를 이용한 고-ldl-콜레스테롤 질환 진단 장치 및 방법 | |
| Djekic et al. | Metabolomics in atherosclerosis | |
| Kishino et al. | Visceral fat thickness in overweight men correlates with alterations in serum fatty acid composition | |
| Schmidt et al. | High apoB/apoA-I ratio is associated with increased progression rate of carotid artery intima-media thickness in clinically healthy 58-year-old men: experiences from very long-term follow-up in the AIR study | |
| Peltier et al. | Elevated serum lipoprotein (a) level is an independent marker of severity of thoracic aortic atherosclerosis | |
| Hyun et al. | Association of apolipoprotein A5 concentration with serum insulin and triglyceride levels and coronary artery disease in Korean men | |
| US20250362315A1 (en) | Quantification of lipoprotein subfraction by ion mobility | |
| KR20160002495A (ko) | 간 효소 및 혈장 대사체를 이용한 심혈관 질환의 예측 또는 진단 방법 | |
| Vaidya et al. | Skin tissue cholesterol assay correlates with presence of coronary calcium | |
| HK1224920A1 (en) | Biomarkers of de novo lipogenesis and methods using the same | |
| HK1224920B (en) | Biomarkers of de novo lipogenesis and methods using the same | |
| Hirayama et al. | Fasting serum free glycerol concentration is a potential surrogate marker of visceral obesity and insulin sensitivity in middle-aged Japanese men |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20171214 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20171214 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20180921 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20181019 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190111 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190702 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20190711 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6557235 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |