JP6523929B2 - Particle beam acceleration system, particle beam acceleration control method, and particle beam therapy apparatus - Google Patents

Description

  Embodiments of the present invention relate to a particle beam acceleration system that accelerates particle beams to high energy, a particle beam acceleration control method, and a particle beam therapy apparatus that treats accelerated particle beams by irradiating the affected area (cancer) with treatment.

  2. Description of the Related Art A particle beam therapy system for treating an affected area of a patient by irradiating a particle beam (a particle in which protons or carbon ions are accelerated to high energy, hereinafter also referred to as "beam") has become widely known.

  In this particle beam therapy system, the beam extracted from the ion source is accelerated by the linear accelerator in the first stage accelerator linac, and the orbit accelerated by the synchrotron (circular accelerator) and the beam raised to a desired energy is used for cancer treatment It is used.

  Particle beam irradiation for conventional treatment is generally a method called the wobbler method. In this wobbler method, the beam size is expanded by passing a scatterer or the like, and the beam axis is moved in a plane within a predetermined range at a high speed, and then a collimator is used to form an irradiation field of the beam. is there. However, in this method, it is difficult to form an accurate shape of the irradiation field, and there are also problems of beam scattering due to the insertion of a collimator and an increase in the irradiation port.

  In recent years, a new irradiation method called a scanning method which overcomes this problem of the wobbler method has been newly developed and is in widespread use. This method does not use a collimator but forms an arbitrary beam irradiation field by current control of a scanning electromagnet.

  By the way, in particle beam therapy, since it is necessary to perform beam irradiation according to the depth of various parts of a patient or an affected part, the extraction time of the beam taken out from a particle beam acceleration system changes according to the contents of treatment . In order to cope with this, conventionally, the operation period of the linac and the operation of the synchrotron are controlled by temporarily delaying the timing of beam incidence to the synchrotron from the linac that accelerates the particle beam generated by the ion source. Synchronization with the

Patent No. 5562627 gazette JP, 2011-233478, A

  However, if synchronization with the operation of the synchrotron is performed by temporarily increasing the operation period of the linac, the operation period of the linac becomes unstable. Therefore, there is a problem that the beam emitted from the synchrotron becomes unstable.

  In particular, in a particle beam therapy system that employs scanning radiation, the time of beam extraction from the acceleration system largely changes depending on the treatment content, so the operation cycle of the linac changes, and the beam emitted from the synchrotron becomes unstable. The effect of becoming is more pronounced.

  The present invention has been made in consideration of such circumstances, and it is possible to smoothly synchronize the linac with the synchrotron while keeping the operation period of the ion source in the linac constant, particle beam acceleration It is an object of the present invention to provide a control method and a particle beam therapy system using accelerated particle beam for treatment of an affected area.

  In the particle beam acceleration system according to the embodiment of the present invention, a linac for outputting a particle beam generated by linearly accelerating ions generated by driving an ion source at a constant period, and a linearly accelerated particle beam synchrotron. And the main accelerator for emitting the particle beam that has reached the desired energy by being circulated and accelerated, and when the particle beam is decelerated and then newly incident after emission, the driving cycle of the ion source is The acceleration control device which calculates the standby time maintained at the set standby energy based on the drive cycle of the ion source and provides the standby time calculated at the time of decelerating the particle beam so that the next incidence timing of the particle beam matches And.

  In the particle beam acceleration control method according to the embodiment of the present invention, a step of outputting a particle beam generated by linearly accelerating ions generated by driving an ion source at a constant period, and synchronizing the linearly accelerated particle beam. The step of causing the particle beam to enter the tron and be accelerated by rotation and emitted to the desired energy, and when the particle beam is decelerated and newly incident after the emission, the driving period of the ion source is Calculating the waiting time to be maintained at the set waiting energy based on the drive cycle of the ion source so as to match the next incidence timing of the particle beam, and providing the waiting time calculated at the time of decelerating the particle beam; It is characterized by including.

  In a particle beam therapy system according to an embodiment of the present invention, a linac for outputting a particle beam generated by linearly accelerating ions generated by driving an ion source at a constant cycle, and a linearly accelerated particle beam synchrotron. And the main accelerator for emitting the particle beam that has reached the desired energy by being circulated and accelerated, and when the particle beam is decelerated and then newly incident after emission, the driving cycle of the ion source is The acceleration control device which calculates the standby time maintained at the set standby energy based on the drive cycle of the ion source and provides the standby time calculated at the time of decelerating the particle beam so that the next incidence timing of the particle beam matches A beam transport system for guiding a beam emitted from the synchrotron to a treatment room, and illumination for irradiating the beam transported to the treatment room to an irradiation object Characterized in that it comprises apparatus and, a.

  According to an embodiment of the present invention, there is provided a particle beam acceleration system, a particle beam acceleration control method, and an accelerated particle beam, capable of smoothly performing synchronization with the linac and the synchrotron while keeping the operation cycle of the ion source in the linac constant. A particle therapy system is provided for use in treating an affected area.

BRIEF DESCRIPTION OF THE DRAWINGS The block diagram of the particle beam acceleration system which concerns on 1st Embodiment applied to the particle beam therapy apparatus. The block diagram which shows an example of a structure of the main accelerator applied to this embodiment. The block diagram which shows the structure of the acceleration control which concerns on 1st Embodiment. (A) to (E) Timing charts of respective signals of linac master trigger, beam permission signal, synchrotron master trigger, synchrotron energy, and beam emission time. 3 is a flowchart showing a control procedure of the acceleration control device in the present embodiment. The flowchart which shows the control procedure of the acceleration control apparatus in this embodiment (continuation of FIG. 5). In 2nd Embodiment, an example of the table preserve | saved at an acceleration control apparatus by making several deceleration energy and the required time of the deceleration calculated according to each waiting energy into the deceleration conditions. The block diagram of the particle beam acceleration system which concerns on 3rd Embodiment applied to the particle beam therapy apparatus.

First Embodiment
Hereinafter, embodiments of the present invention will be described based on the attached drawings.
As shown in FIG. 1, the particle beam acceleration system 10 according to the first embodiment includes: a linac 11 for outputting a particle beam obtained by linearly accelerating ions generated by driving the ion source 14 at a constant cycle; The primary particle 12 is made incident on the synchrotron 19 and circulated and accelerated to emit the particle beam which has reached the desired energy, and the ion beam when the particle beam is decelerated and made to newly enter after emission. The standby time maintained at the set standby energy is calculated based on the drive cycle of the ion source 14 so that the next incidence timing of the particle beam matches the drive cycle of the source 14, and the standby time calculated at the time of decelerating the particle beam. And an acceleration control device 13 provided. Here, the case where the particle beam acceleration system 10 is applied to the particle beam therapy apparatus 100 that uses the accelerated beam to treat the affected area of a patient will be described.

  The particle beam acceleration system 10 according to the present embodiment provides a standby time for maintaining the set standby energy at the time of decelerating the beam so that the next incidence timing of the particle beam coincides with the drive cycle of the ion source 14. The synchronization between the linac 11 and the synchrotron 19 is smoothly performed while keeping the operation cycle of the ion source 14 in the linac 11 constant.

Each configuration will be specifically described.
The linac 11 includes an ion source 14, a linear accelerator 15, a chopper 16, and a linac controller 17.

  In the ion source 14, laser light is focused and irradiated on a solid target (not shown). Then, the element of the solid target is evaporated and ionized by the energy of the laser light, thereby generating plasma. The ion source 14 is driven by the linac controller 17 at a constant cycle.

  The linear accelerator 15 is an accelerator that introduces a plasma generated from the ion source 14 to extract ions, and outputs a beam obtained by accelerating the extracted ions.

  The chopper 16 is provided between the ion source 14 and the linear accelerator 15 to limit the input to the linear accelerator 15 of the ions generated by the ion source 14. It is used to control the output timing.

  The control of the chopper 16 is performed by the linac controller 17. When the linac controller 17 receives the control signal of the beam permission, the ion generated by the ion source 14 is guided to the linear accelerator 15 to output the beam. On the other hand, when there is no beam permission control signal, the ions generated by the ion source 14 are deviated from the input direction of the linear accelerator 15 and the linear accelerator 15 does not execute the beam output.

  The linac controller 17 outputs a drive command to the ion source 14 and the chopper 16 based on a control signal that defines the operation timing output from the acceleration controller 13 to control the ion source 14 and the chopper 16.

  Then, the beam accelerated by the linear accelerator 15 is incident on the synchrotron 19 of the main accelerator 12 via the incident transport system 18.

The main accelerator 12 includes a synchrotron 19 and a synchrotron controller 20.
The synchrotron 19 is a circular accelerator for circumferentially accelerating a beam incident from the incident transport system 18 to a desired energy (energy required for treatment).

  The synchrotron controller 20 controls the synchrotron 19 by outputting a drive command to the synchrotron 19 based on a control signal that defines the operation timing from the beam incidence to the next beam incidence output from the acceleration controller 13. Do.

  FIG. 2 is a block diagram showing an example of the configuration of the main accelerator 12 applied to the present embodiment (see FIG. 1 as needed).

  The incident septum 25 for causing the beam to enter the synchrotron 19 from the incident transport system 18 and stably orbiting and accelerating (or decelerating) the beam, the deflection electromagnet 26, the four-pole electromagnet 27, and the six-pole electromagnet 28. Incident accelerating devices such as high frequency accelerating cavities 29 are arranged on the circumference. These incident acceleration devices are driven by the synchrotron controller 20, and the beam output from the linac 11 is incident on the synchrotron 19. Then, it is accelerated by rotation and raised from incident energy to desired energy (energy required for treatment).

  Further, the synchrotron 19 is provided with an emitting device such as an emitting electromagnet 30 for emitting the beam to the outside. These emission devices are driven by the synchrotron controller 20, and the beam in the synchrotron 19 is emitted to the outside of the synchrotron 19.

  The beam which has been boosted to a desired energy by the synchrotron 19 is guided to the treatment room 22 through the beam delivery and transportation system 21 (FIG. 1). An irradiation device 23 is disposed in the treatment room 22, and an arbitrary irradiation field is formed on an irradiation target (patient) by scanning irradiation, and the diseased part of the patient is irradiated.

  The treatment control unit 24 outputs a beam request to the acceleration control unit 13 of the particle beam acceleration system 10 at the time of treatment. In addition, the beam request output is stopped at the end of treatment or at the time of temporary stop.

  FIG. 3 is a block diagram showing the configuration of acceleration control in the particle beam acceleration system 10 according to the first embodiment (see FIG. 1 as appropriate).

  The acceleration control device 13 includes a linac master trigger output unit 31, a beam permission signal output unit 32, a synchrotron master trigger output unit 33, a beam request reception unit 34, an emission permission signal output unit 35, an incidence permission condition setting unit 36, and a deceleration control. A unit 37 is provided.

  The linac master trigger output unit 31 outputs a linac master trigger 50 for driving the ion source 14 of the linac 11 at a constant cycle to the linac controller 17. The linac controller 17 receives the linac master trigger 50, applies an ion source operation command 51 to the ion source 14, and drives the ion source 14 in a constant cycle.

  The beam permission signal output unit 32 outputs a beam permission signal 52 for permitting beam acceleration in the linear accelerator 15 with respect to control of the chopper 16 of the linac 11. At the start of operation of the particle beam acceleration system 10, the beam permission signal 52 is output in synchronization with the output timing of the linac master trigger 50.

  The linac controller 17 receives the beam permission signal 52, gives a chopper operation command 53 to the chopper 16, inputs ions generated by the ion source 14 into the linear accelerator 15, and accelerates the beam.

  The synchrotron master trigger output unit 33 outputs to the synchrotron controller 20 a synchrotron master trigger 54 for causing the beam output from the linac 11 to enter the synchrotron 19 and accelerate it. At the start of operation of the particle beam acceleration system 10, the synchrotron master trigger 54 is output in synchronization with the output timing of the linac master trigger 50.

  The synchrotron controller 20 receives the synchrotron master trigger 54 and provides an incident operation command 55 to the incident acceleration device 40 of the synchrotron 19 so that the beam is incident on the synchrotron 19 and accelerated.

  The beam request reception unit 34 receives the beam request signal 56 from the treatment control device 24 as needed.

  When the beam request reception unit 34 receives the beam request signal 56, the emission permission signal output unit 35 outputs the emission permission signal 57 to the synchrotron control device 20. When receiving the emission permission signal 57, the synchrotron control device 20 determines whether or not the beam in the synchrotron 19 can be emitted, and then gives the emission permission command 58 to the emission device 41 to emit the beam in the synchrotron 19 Let On the other hand, when the beam request signal 56 is stopped, the emission permission signal 57 is stopped, and the beam emission ends.

  Since the emission of the beam is stopped (for example, when the beam request signal 56 is stopped) and the new beam is made to enter the synchrotron 19 again, the entrance permission condition setting unit 36 When decelerating, standby energy is set to temporarily maintain energy. The standby energy is set to an energy value higher than the incident energy of the beam incident from the linac 11.

  When the beam request signal 56 is stopped, the incidence permission condition setting unit 36 calculates the waiting time based on the output cycle of the linac master trigger 50 in order to match the next beam incidence with the output timing of the linac master trigger 50. . A specific method of calculating the waiting time will be described later.

  Then, the entrance permission condition setting unit 36 sets the sum of three times of the time necessary for decelerating to the standby energy, the standby time, and the time required for decelerating from the standby energy to the incident energy as the incident permission condition. Do. This incidence permission condition is the time required to match the next beam incidence with the output timing of the linac master trigger 50.

  The deceleration control unit 37 receives the standby energy and the standby time from the incident permission condition setting unit 36, and outputs a deceleration control signal 59 to the synchrotron control device 20 so that the beam is decelerated under these setting conditions. The synchrotron controller 20 receives the deceleration control signal 59 and decelerates the beam in the synchrotron 19 based on the set standby energy and standby time.

  Then, the beam permission signal output unit 32 establishes the entrance permission condition set by the entrance permission condition setting unit 36, in other words, the output of the linac master trigger 50 immediately after the entrance permission condition elapses after stopping the beam emission. A beam permission signal 52 is output to the linac controller 17 in accordance with the timing.

  At this time, the synchrotron master trigger output unit 33 linac controls the synchrotron master trigger 54 in accordance with the output timing of the linac master trigger 50 at the latest after the incidence permission condition set by the incident permission condition setting unit 36 is satisfied. It outputs to the device 17.

  Thus, the linac master trigger 50 for controlling the ion source 14 is maintained at a constant cycle, and the beam permission signal 52 for defining the timing of beam injection to the synchrotron 19 based on the injection permission condition and the synchrotron master trigger By outputting 54, synchronization between the linac 11 and the synchrotron 19 is achieved.

  Subsequently, a specific calculation method in the incident permission condition setting unit 36 will be described with reference to a timing chart shown in FIG.

  FIGS. 4A to 4E show timing charts of each signal of the linac master trigger 50, the beam permission signal 52, and the beam energy of the synchrotron master trigger 54 and the synchrotron 19 and the beam emission time (FIG. As appropriate, refer to FIGS. 1 and 3).

The output of the linac master trigger 50 is repeated at a constant period of _Tio (for example, one second) (FIG. 4A).

Then, in accordance with the linac master trigger 50, the beam permission signal 52 and the synchrotron master trigger 54 are output (FIG. 4 (B), FIG. 4 (C)). Beam is incident from the linac 11 in the synchrotron 19, the beam is circulating accelerated at time T _ac reach the desired energy (FIG. 4 (D)).

At this time, if the beam request signal 56 is output from the treatment control unit 24, the beam is emitted from the synchrotron 19 and supplied to the treatment room 22 for treatment. Beam emission continues for a time T _ex from the start of the emission until the beam request signal 56 is stopped (FIG. 4 (E)).

The incident permission condition setting unit 36 calculates the waiting time T _w with the set standby energy according to the following equation (1) when a new beam is incident again after the beam request signal 56 is stopped. Here, N is the minimum number of non-negative values of T _w . In addition, since the speed of beam deceleration is constant, the deceleration time T _{d1 to} the standby energy and the deceleration time T _d2 from the standby energy are both constant.

T _w = N × T _io − (T _d1 + T _d2 + T _ac + T _ex ) (1)
T _w : Waiting time at standby energy (s)
T _io : Output period of linac master trigger (s)
T _d1 : Deceleration time to standby energy (s)
T _d2 : Deceleration time from standby energy (s)
T _ac : Acceleration time (s)
T _ex : Emission time (s)

Then, the entrance permission condition setting unit 36 sets the time of T _d1 + T _d2 + T _w as the entrance permission condition after the end of emission of the beam.

After completion of beam emission, the beam in the synchrotron 19 decelerates to standby energy over time T _d1 and maintains time T _w at standby energy. And it decelerates to incident energy over the time of _Td2 (FIG. 4 (D)).

  The beam permission signal output unit 32 outputs the beam permission signal 52 to the linac control device 17 according to the output timing of the linac master trigger 50 after the entrance permission condition has elapsed after stopping the beam emission (FIG. 4 (B)). .

  Similarly, after the entrance permission condition has elapsed, the synchrotron master trigger output unit 33 outputs the synchrotron master trigger 54 to the synchrotron controller 20 in accordance with the output timing of the linac master trigger 50 (FIG. 4 (C) ).

  As described above, when the linac master trigger 50 is output at a constant cycle and a new beam is incident on the synchrotron 19, a standby time maintained by standby energy is provided, and the synchro that defines the beam incident on the synchrotron 19. The tron master trigger 54 is adjusted to the output period of the linac 11. As a result, the waiting time for incidence on the synchrotron 19 is minimized, and the operations of the linac 11 and the synchrotron 19 can be smoothly synchronized, and efficient accelerator operation can be performed.

  5 and 6 show flowcharts of control procedures of the particle beam acceleration system 10 according to the present embodiment (see FIGS. 1 and 3 as appropriate).

  The linac master trigger output unit 31 starts the output of the linac master trigger 50 (S10). As a result, the ion source 14 is driven in a constant cycle to generate ions (S11).

  The beam permission signal 52 and the synchrotron master trigger 54 are output in synchronization with the output timing of the linac master trigger 50, and the beam enters the synchrotron 19 (S12 to S14). Then, the incident beam is circularly accelerated to reach a desired energy (S15).

  At this time, if there is a beam request signal 56 from the treatment control device 24, the beam is emitted and supplied to the treatment room 22 (S16: YES, S17). If there is no beam request, orbit acceleration is continued (S16: NO).

Thereafter, when the beam request is stopped, the incident permission condition setting unit 36 calculates the waiting time T _w at the set standby energy based on the cycle of the linac master trigger 50 (S18: YES, S19). On the other hand, when the beam request continues, the beam supply to the treatment room 22 is continued (S18: NO).

Then, the entrance permission condition setting unit 36 sets the T _d1 + T _d2 + T _w field as the entrance permission condition after the end of the beam emission (S20). T _d1 represents a deceleration time to standby energy, and T _d2 represents a deceleration time from standby energy.

The synchrotron controller 20 decelerates the beam to the set standby energy (S21). Then, after the standby energy is maintained for the standby time T _w , the beam is further decelerated (S22).

  Then, after the incident permission condition is satisfied, the beam permission signal 52 and the synchrotron master trigger 54 are output in synchronization with the output timing of the linac master trigger 50, and the beam is incident on the synchrotron 19 (S23: YES, S24: YES, S25, S26).

  On the other hand, when the incident permission condition is not satisfied (S23: NO) or when the output timing of the linac master trigger 50 does not match (S24: NO), neither the beam permission signal 52 nor the synchrotron master trigger 54 is output. Is not incident on the synchrotron 19.

  Then, S14 to S26 are executed to repeat the beam incidence to the synchrotron 19, the acceleration, and the emission until the treatment ends.

  By accelerating and controlling the particle beam in this manner, synchronization between the linac 11 and the synchrotron 19 can be smoothly performed while keeping the operation cycle of the ion source 14 in the linac 11 constant. As a result, even if the beam emission time at the synchrotron 19 changes, new incidence of the beam can be stably and appropriately performed.

  Further, by setting the standby energy, stable beam supply can be performed with small temperature fluctuation of the entire synchrotron 19.

  Furthermore, the waiting time of the particle beam of the synchrotron 19 from the linac 11 can be minimized, and the treatment time can be minimized when the particle beam acceleration system 10 is applied to a treatment apparatus.

  Note that, instead of using the chopper 16, the incident acceleration device 40 (FIG. 3) of the synchrotron 19 is configured so that the beam output from the linac 11 is not incident on the synchrotron 19 when it does not match the synchrotron master trigger 54. You may.

  In this case, it is attempted to supply a beam from the linac 11 to the synchrotron 19 in a cycle of beam operation of the linac 11.

  However, the beam is incident on the synchrotron 19 only at the timing of the synchrotron master trigger 54, and the beam of the linac 11 generated at other timings becomes invalid, and the same effect as that of the first embodiment can be obtained. With this configuration, since the beam incidence can be controlled by the synchrotron master trigger 54, the configuration of the beam permission signal output unit 32 and the like can be omitted, and the configuration can be simplified.

Second Embodiment
Next, a particle beam acceleration system 10 according to a second embodiment will be described. About 2nd Embodiment, since it becomes the same structure as the structure (FIG. 1) of 1st Embodiment, description of drawing is abbreviate | omitted.

  In the second embodiment, the acceleration control device 13 stores a plurality of standby energy and a required time for deceleration calculated according to each standby energy as a deceleration condition, and particle beam based on the deceleration condition selected by the user. Slow down.

FIG. 7 shows an example of the deceleration condition, and the required time for deceleration calculated according to three standby energy and each standby energy (deceleration time T _d1 before standby, deceleration time T _d2 after standby) And are shown in the table as deceleration conditions.

  The acceleration control device 13 decelerates the beam under the decelerating condition set by the user at the time of deceleration when decelerating the particle beam and causing the particle beam to newly enter after emission.

  With such a configuration, it is possible to change the standby energy in accordance with the seasonal change of the air temperature or the cooling water temperature, the temperature fluctuation of the synchrotron 19 is small, and more stable operation can be performed.

Third Embodiment
FIG. 8 shows a configuration diagram of a particle beam acceleration system 10 according to the third embodiment. Parts in FIG. 8 having the same configurations or functions as those in FIG. 1 are denoted by the same reference numerals, and redundant description will be omitted.

  The particle beam acceleration system 10 according to the third embodiment is different from that according to the first embodiment in that the acceleration control device 13 further includes a beam amount measurement unit 42 that measures the beam amount of a beam traveling around the synchrotron 19. When the amount of beams obtained is less than a predetermined target value, the particle beam is decelerated to newly enter.

  When the beam amount of the synchrotron 19 measured by the beam amount measurement unit 42 falls below a predetermined determination value (the beam amount necessary for stable treatment), the end of beam emission and the start of deceleration are performed. The beam amount measurement unit 42 utilizes what is generally used for measuring the beam current of the synchrotron 19.

  Thereby, the beam extraction time can be appropriately managed based on the beam amount of the synchrotron 19, and the accelerator can be operated efficiently.

  According to the particle beam acceleration system of each embodiment described above, the standby time maintained by the set standby energy is provided so that the next incidence timing of the particle beam to the synchrotron matches the drive cycle of the ion source. The synchronization between the linac and the synchrotron can be smoothly performed while keeping the operation cycle of the ion source in the linac constant.

  While certain embodiments of the present invention have been described, these embodiments have been presented by way of example only, and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, substitutions, and modifications can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and the gist of the invention, and are included in the invention described in the claims and the equivalent scope thereof.

  The acceleration control device of the particle beam acceleration system described above is a control in which a processor such as a dedicated chip, a field programmable gate array (FPGA), a graphics processing unit (GPU), or a central processing unit (CPU) is highly integrated. Device, storage device such as ROM (Read Only Memory) or RAM (Random Access Memory), external storage device such as HDD (Hard Disk Drive) or SSD (Solid State Drive), display device such as display, mouse An input device such as a keyboard and the like, and a communication I / F are provided, and can be realized by a hardware configuration using a normal computer.

  DESCRIPTION OF SYMBOLS 10 ... Particle beam acceleration system, 11 ... Linac, 12 ... Main accelerator, 13 ... Acceleration control apparatus, 14 ... Ion source, 15 ... Linear accelerator, 16 ... Chopper, 17 ... Linac control apparatus, 18 ... Incident transport system, 19 ... Synchrotron, 20: Synchrotron control device, 21: Ejection transport system, 22: Treatment room, 23: Irradiation device, 24: Treatment control device, 25: Incident septum, 26: Deflection electromagnet, 27: Four-pole electromagnet, 28 ... 6 pole electromagnet, 29 ... high frequency acceleration cavity, 30 ... emission electromagnet, 31 ... linac master trigger output unit, 32 ... beam permission signal output unit, 33 ... synchrotron master trigger output unit, 34 ... beam request reception unit, 35 ... Emission permission signal output unit, 36 ... Incident permission condition setting unit, 37 ... Deceleration control unit, 40 ... Incident acceleration device, 41 ... Emission device, 42 ... Beam amount measurement unit 50 ... linac master trigger, 51 ... ion source operation command, 52 ... beam permission signal, 53 ... chopper operation command, 54 ... synchrotron master trigger, 55 ... incident operation command, 56 ... beam request signal, 57 ... emission permission signal, 58 ... Ejection operation command, 59 ... Deceleration control signal, 100 ... Particle beam therapy system.

Claims (7)

A linac that outputs a particle beam in which the generated ions are linearly accelerated by driving the ion source at a constant period;
A main accelerator that injects the linearly accelerated particle beam into a synchrotron and causes the particle beam to accelerate to a desired energy level;
When the particle beam is decelerated and made to newly enter after emission, the waiting time maintained by the set waiting energy is set in the ion source so that the next incidence timing of the particle beam matches the driving cycle of the ion source. And an acceleration control device for providing the waiting time calculated at the time of decelerating the particle beam, which is calculated based on a drive cycle. The acceleration control device
A linac master trigger output unit that outputs a linac master trigger that drives the ion source of the linac at a constant cycle;
A synchrotron master trigger output unit that outputs a synchrotron master trigger that causes the particle beam to be incident on the synchrotron;
When the particle beam is decelerated and made to newly enter after emission, the waiting time is calculated based on the drive cycle of the ion source, and the incidence permission condition for defining the next incidence timing of the particle beam is set. Condition setting unit,
A deceleration control unit for decelerating the particle beam in the main accelerator based on the waiting time and the waiting energy;
The particle beam acceleration according to claim 1, wherein the synchrotron master trigger output unit outputs the synchrotron master trigger according to the output timing of the linac master trigger after the incidence permission condition is satisfied. system. The linac comprises a chopper capable of limiting the input of the ions to a linear accelerator which linearly accelerates the beam,
The acceleration control device has a beam permission signal output unit that outputs a beam permission signal that permits the particle beam to be input to the linear accelerator.
The particle beam acceleration system according to claim 2, wherein the beam permission signal output unit outputs the beam permission signal in accordance with an output timing of the linac master trigger after the incidence permission condition is satisfied.   The acceleration control device stores a plurality of standby energy and a required time for deceleration calculated according to each standby energy as a deceleration condition, and decelerates the particle beam based on the deceleration condition selected by the user. The particle beam acceleration system according to any one of claims 1 to 3, characterized in that A beam amount measuring unit for measuring a beam amount of the beam traveling around the synchrotron;
The said acceleration control device decelerates the said particle beam, and makes it newly enter, when the measured beam quantity is below a predetermined judgment value. Particle beam acceleration system described in. Driving the ion source at a constant period to output a particle beam in which linearly generated ions are accelerated;
Injecting the linearly accelerated particle beam into a synchrotron, and circumferentially accelerating the particle beam to emit the particle beam having reached a desired energy;
When the particle beam is decelerated and made to newly enter after emission, the waiting time maintained by the set waiting energy is set in the ion source so that the next incidence timing of the particle beam matches the driving cycle of the ion source. And D. providing the waiting time calculated at the time of decelerating the particle beam calculated based on a drive cycle. A linac that outputs a particle beam in which the generated ions are linearly accelerated by driving the ion source at a constant period;
A main accelerator that injects the linearly accelerated particle beam into a synchrotron and causes the particle beam to accelerate to a desired energy level;
When the particle beam is decelerated and made to newly enter after emission, the waiting time maintained by the set waiting energy is set in the ion source so that the next incidence timing of the particle beam matches the driving cycle of the ion source. An acceleration control device which provides the waiting time calculated at the time of deceleration of the particle beam, which is calculated based on a drive cycle;
A beam transport system for guiding a beam emitted from the synchrotron to a treatment room;
An irradiation device for irradiating the irradiation target with the beam transported to the treatment room.

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