JP6494580B2 - 微小流体装置 - Google Patents
微小流体装置 Download PDFInfo
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- JP6494580B2 JP6494580B2 JP2016190355A JP2016190355A JP6494580B2 JP 6494580 B2 JP6494580 B2 JP 6494580B2 JP 2016190355 A JP2016190355 A JP 2016190355A JP 2016190355 A JP2016190355 A JP 2016190355A JP 6494580 B2 JP6494580 B2 JP 6494580B2
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Description
本発明の一実施形態について、図1〜図3に基づいて説明すれば以下の通りである。
図1は、本実施形態にかかる微小流体装置1の要部の概略構成の一例を模式的に示す断面図である。図2は、本実施形態にかかる微小流体装置1における薄膜電子回路層12の概略構成の一例を模式的に示す平面図である。
図1に示すアレイ基板10は、駆動素子として、マトリクス状に配置された複数のTFT20を有するアクティブマトリクス型のTFT基板である。
図1に示すように、対向基板40は、支持基板である絶縁基板41におけるアレイ基板10との対向面に、対向電極(共通電極)として、電極42が設けられた構成を有している。
アレイ基板10と対向基板40との間隙には、アレイ基板10と対向基板40と図示しないシール材とによって囲まれた内部空間50が形成されている。
液滴51は、撥水層18の表面が、液滴51と気体(もしくは非イオン性液体52)とに接触しているときに、これら3相の接触する境界線において液滴51の液面が撥水層18の表面となす角度で示される接触角θをなして配されている。
次に、微小流体装置1の製造方法について接続する。まず、微小流体装置1の各層の材料および形成方法について説明する。
上述したように、微小流体装置1は、撥水層18・43で導電性を有する液滴51を挟み、液滴51と、該液滴51の直下の誘電体層15の下の電極14との間に電位差を生じさせることにより、エレクトロウェッティング現象を生じさせて、液滴51を、撥水層18上で移動させる。
本実施形態について、図4に基づいて説明すれば、以下の通りである。なお、本実施形態では、主に、実施形態1との相違点について説明するものとし、実施形態1で用いた構成要素と同一の機能を有する構成要素には同一の番号を付し、その説明を省略する。
図4は、本実施形態にかかる微小流体装置1の要部の概略構成の一例を示す断面図である。
本実施形態にかかる微小流体装置1は、実施形態1において、第2平坦化樹脂層形成工程で、コンタクトホール19の内外におけるコーティングギャップ等のスリットコート条件を変更するとともに、フォトリソグラフィの条件を変更する以外は、実施形態1と同様にして製造することができる。
本実施形態によれば、コンタクトホール19内が第2平坦化樹脂層16で埋められていることで、実施形態1と同様の効果を得ることができる。
本実施形態について、図5に基づいて説明すれば、以下の通りである。なお、本実施形態では、主に、実施形態1、2との相違点について説明するものとし、実施形態1、2で用いた構成要素と同一の機能を有する構成要素には同一の番号を付し、その説明を省略する。
図5は、本実施形態にかかるアレイ基板10の要部の概略構成の一例を示す断面図である。
本実施形態にかかる微小流体装置1は、実施形態2において、イオンバリア層形成工程と、第2平坦化樹脂層形成工程との順番を入れ替える以外は、実施形態2と同様にして製造することができる。
本実施形態によれば、コンタクトホール19内が第2平坦化樹脂層16で埋められているとともに、第2平坦化樹脂層16が、イオンバリア層17を介してコンタクトホール19の外部の電極14を覆っていることで、実施形態1、2と同様の効果を得ることができる。
本実施形態について、図6に基づいて説明すれば、以下の通りである。なお、本実施形態では、主に、実施形態1〜3との相違点について説明するものとし、実施形態1〜3で用いた構成要素と同一の機能を有する構成要素には同一の番号を付し、その説明を省略する。
図6は、本実施形態にかかる微小流体装置1の要部の概略構成の一例を示す断面図である。
典型的な免疫アッセイでは、磁性粒子53に結合された第1の抗体(磁性粒子−抗体複合体)を含む液滴51と、ターゲットを含む液滴51とを混合することで、ターゲットが、磁性粒子−抗体複合体に結合される。その後、この液滴51に、蛍光物に共役された第2の抗体を含む液滴51が加えられると、第2の抗体は、磁性粒子−抗体複合体に結合されたターゲットに結合して、磁性粒子53、第1の抗体、ターゲット、および第2の抗体の複合体である結合抗体複合体を形成する。
以上のように、本実施形態にかかる微小流体装置1は、磁石61を備え、磁石61を用いて磁性粒子53の固定化あるいは移動を行う。
本発明の態様1にかかる微小流体装置1は、(I)複数の第1電極(電極14・14a・14b)と、上記複数の第1電極にそれぞれ電気的に接続され、上記複数の第1電極をそれぞれ駆動する複数の駆動素子(TFT20)と、上記複数の駆動素子を覆う第1平坦化樹脂層13と、上記複数の第1電極を覆う誘電体層15と、上記誘電体層15を覆う第1撥水層(撥水層18)とを有する第1基板(アレイ基板10)と、(II)上記第1基板に対向配置されており、上記複数の第1電極に対向配置された、少なくとも1つの第2電極(電極42)と、上記少なくとも1つの第2電極を覆う第2撥水層(撥水層43)とを有し、上記第1基板との間に、導電性を有する微小流体(液滴51)を、上記複数の第1電極を跨いで移動させる内部空間50を形成する第2基板(対向基板40)とを備え、上記複数の第1電極は、上記第1平坦化樹脂層13上に設けられているとともに、遮光性を有する金属電極である。
2 セル
10 アレイ基板
11、41 絶縁基板
12 薄膜電子回路層
13 第1平坦化樹脂層
14、14a、14b、42 電極
15 誘電体層
16 第2平坦化樹脂層
17 イオンバリア層
18、43 撥水層
19 コンタクトホール
20 TFT(駆動素子)
21 ゲート電極
22 ゲート絶縁膜
23 半導体層
24 ソース電極
25 ドレイン電極
31 電極アレイ
32 アレイ素子
33 アレイ素子回路
34 行駆動回路
35 列駆動回路
36 シリアルインターフェース
37 電圧供給インターフェース
38 接続ワイヤ
40 対向基板
41 絶縁基板
50 内部空間
51 液滴(微小流体)
52 非イオン性液体
53 磁性粒子
61 磁石
61S S極
61N N極
Claims (8)
- 複数の第1電極と、上記複数の第1電極にそれぞれ電気的に接続され、上記複数の第1電極をそれぞれ駆動する複数の駆動素子と、上記複数の駆動素子を覆う第1平坦化樹脂層と、上記複数の第1電極を覆う誘電体層と、上記誘電体層を覆う第1撥水層とを有する第1基板と、
上記第1基板に対向配置されており、上記複数の第1電極に対向配置された、少なくとも1つの第2電極と、上記少なくとも1つの第2電極を覆う第2撥水層とを有し、上記第1基板との間に、導電性を有する微小流体を、上記複数の第1電極を跨いで移動させる内部空間を形成する第2基板とを備え、
上記複数の第1電極は、上記第1平坦化樹脂層上に設けられているとともに、遮光性を有する金属電極であり、
上記第1平坦化樹脂層は、上記第1撥水層の凹凸を低減するための平坦化層であることを特徴とする微小流体装置。 - 上記複数の第1電極は、上記第1平坦化樹脂層に設けられたコンタクトホールを介して上記複数の駆動素子にそれぞれ接続されており、
上記誘電体層は、上記コンタクトホールを埋める少なくとも1層の第2平坦化樹脂層を含んでいることを特徴とする請求項1に記載の微小流体装置。 - 上記誘電体層はさらに、無機材料からなる少なくとも1層のイオンバリア層を含んでいることを特徴とする請求項2に記載の微小流体装置。
- 上記第2平坦化樹脂層が上記複数の第1電極を覆っており、上記イオンバリア層が上記第2平坦化樹脂層を覆っていることを特徴とする請求項3に記載の微小流体装置。
- 上記イオンバリア層が上記複数の第1電極を覆っており、上記第2平坦化樹脂層が上記イオンバリア層を覆っていることを特徴とする請求項3に記載の微小流体装置。
- 上記第2平坦化樹脂層は、上記コンタクトホール内および上記複数の第1電極間のうち少なくとも上記コンタクトホール内に設けられており、上記第1電極上には設けられておらず、
上記イオンバリア層は、上記第2平坦化樹脂層および上記複数の第1電極を覆っていることを特徴とする請求項3に記載の微小流体装置。 - 上記微小流体は磁性粒子を含む微小流体であり、
上記磁性粒子を固定化する磁石をさらに備え、
上記第1電極は、非磁性金属材料で形成されていることを特徴とする請求項1〜6の何れか1項に記載の微小流体装置。 - 上記第1電極はモリブデンで形成されていることを特徴とする請求項1〜7の何れか1項に記載の微小流体装置。
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