JP6488283B2 - Ｃ−ｃケモカイン受容体５型（ｃｃｒ５）遺伝子を開裂するｌａｇｌｉｄａｄｇホーミングエンドヌクレアーゼおよびその用途 - Google Patents

Ｃ−ｃケモカイン受容体５型（ｃｃｒ５）遺伝子を開裂するｌａｇｌｉｄａｄｇホーミングエンドヌクレアーゼおよびその用途 Download PDF

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JP6488283B2
JP6488283B2 JP2016516171A JP2016516171A JP6488283B2 JP 6488283 B2 JP6488283 B2 JP 6488283B2 JP 2016516171 A JP2016516171 A JP 2016516171A JP 2016516171 A JP2016516171 A JP 2016516171A JP 6488283 B2 JP6488283 B2 JP 6488283B2
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ジョーダン ジャージャー
ジョーダン ジャージャー
アレクサンダー アストラカン
アレクサンダー アストラカン
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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JP2016516171A 2013-05-31 2014-05-28 Ｃ−ｃケモカイン受容体５型（ｃｃｒ５）遺伝子を開裂するｌａｇｌｉｄａｄｇホーミングエンドヌクレアーゼおよびその用途 Active JP6488283B2 (ja)

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DKPA201370302 2013-05-31
DKPA201370302 2013-05-31
PCT/EP2014/061186 WO2014191525A1 (en) 2013-05-31 2014-05-28 A laglidadg homing endonuclease cleaving the c-c chemokine receptor type-5 (ccr5) gene and uses thereof

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JP2016520319A5 JP2016520319A5 (enExample) 2017-07-06
JP6488283B2 true JP6488283B2 (ja) 2019-03-20

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CA2913871A1 (en) 2014-12-04
AU2014273089A1 (en) 2015-12-24
EP3004149A1 (en) 2016-04-13
JP2016520319A (ja) 2016-07-14
EP3004149B1 (en) 2018-12-19
WO2014191525A1 (en) 2014-12-04
CA2913871C (en) 2021-07-13
AU2014273089B2 (en) 2018-02-22
US20160102323A1 (en) 2016-04-14
US10006052B2 (en) 2018-06-26

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