JP6423810B2 - Medication support system - Google Patents

Description

  The present invention relates to a medication support system that supports a patient undergoing medication treatment, and more particularly to a medication support system that supports a patient who exhibits symptoms such as side effects associated with medication.

  Some patients who are taking medication at home want to consult with medical personnel such as doctors and pharmacists, including symptoms that may cause side effects of medication if the body becomes unwell during the medication period There are people.

  On the other hand, in general, in addition to the symptoms that occurred in the patient, the medical staff who receives the consultation accurately grasps the situation such as the type of medicine taken, the time of taking, the time when the symptom appeared, There is a desire to accurately determine the situation, including whether it is a side effect of the drug, and to improve the accuracy of the subsequent determination. For this purpose, it is necessary for the patient to accurately transmit information other than symptoms to medical personnel.

  However, requiring the patient to communicate the correct situation increases the burden on the patient. In other words, specialized terms are used for the drug names, and there are patients who are prescribed a plurality of types of drugs, and it is a burden on the patient to accurately convey the drug names one by one. In addition, there are drugs that cause side effects after a considerable amount of time has elapsed since taking them, drugs that should be checked for multiple symptoms, and the like. In order to convey an accurate situation about these, the patient needs to do some work, such as writing down medication time and onset time with a drug name, and this is a burden for the patient.

  As an apparatus that provides information such as patient symptoms, for example, Patent Document 1 discloses an apparatus that records symptoms of side effects, onset time, medication time and elapsed time, and provides such information to patients and doctors. Has been.

Special table 11-511056 gazette

  The apparatus described in Patent Document 1 acquires information such as a taking time by key input by a patient. For this reason, in order for medical personnel to accurately grasp the relationship between the onset time and the taking time, it is necessary for the patient to perform key input without forgetting after taking the medicine. In addition, a patient who has been prescribed a plurality of types of drugs needs to key in the name of the drug actually taken in order to distinguish the drugs taken. However, if a drug name different from the name of the drug actually taken is keyed, it becomes difficult for the medical staff to accurately grasp the relationship between the onset time and the medication time. In order to cope with this, even a patient who does not have medical knowledge is required to input keys accurately without making a mistake in the name of the medicine taken, but this work places a burden on the patient.

  Therefore, the present invention has been made in view of the above problems, and an object of the present invention is to provide a medication support system that can generate accurate information on the status of a patient who has taken the medication while reducing the burden on the patient.

According to one aspect of the present invention, a drug dispenser device that provides a drug to a patient, a medication support terminal that acquires the condition of the patient as status information, and the drug dispenser device provides the drug. A history list generating means for generating a history list by associating the time when the drug is provided with the drug information indicating the provided drug, and the status information is acquired by the medication support terminal. , Using the history list, the drug information, the dose time, the status information, and a status list generating unit that generates a status list that associates the status acquisition time when the status information was acquired, the drug information, A storage means for storing a drug state association list associating a state that can appear to the patient by taking the drug; Status list generation means uses the drug information associated with the state of the patient in the pharmaceutical association state list indicated by the state information, generates the status list is the medication support system, characterized in that .

In addition, according to one aspect of the present invention, a drug dispenser device that provides a drug to a patient, a medication support terminal that acquires the state of the patient as state information, and the drug dispenser device provided the drug. In response, the status information is acquired by the history list generating means for generating a history list by associating the time when the drug was provided with the drug information indicating the provided drug, and the medication support terminal. Accordingly, using the history list, the drug information, the dose time, the status information, and a status list generating unit that generates a status list that associates the status acquisition time when the status information was acquired, the state list generating means includes a most recent dose time of the status acquisition time of the taking time included in the history list, with relation to the dosing time With, said agent information that is to generate the state list, there medication support system, characterized in that.

In addition, according to one aspect of the present invention, a drug dispenser device that provides a drug to a patient, a medication support terminal that acquires the state of the patient as state information, and the drug dispenser device provided the drug. In response, the status information is acquired by the history list generating means for generating a history list by associating the time when the drug was provided with the drug information indicating the provided drug, and the medication support terminal. Accordingly, using the history list, the drug information, the dose time, the status information, and a status list generating unit that generates a status list that associates the status acquisition time when the status information was acquired, the state list generating means includes taking time within a predetermined time period retroactively from the state acquisition time of the taking time included in the history list, the clothes And the drug information associated with the time, is used to generate the state list, a medication support system, characterized in that.

Further, the medication assistance system, have you in the state list, based on the number of the status information indicating the status of the calculation target associated with the drug information indicative of medicament to be calculated, the occurrence of the state of the calculation target It is preferable to further have an analysis means for calculating the rate .

  In addition, it is preferable that the medication support system further includes an analysis unit that analyzes a time difference between the dose time associated with the status list and the status acquisition time and outputs the analysis result.

  The medication support system further includes at least a patient portable terminal that inputs that the patient has taken the medicine, and the medicine dispenser device further takes the patient on the go according to a predetermined operation. The history list generating means further associates the outing information with the drug information of the medicine provided for taking at the outing, and the state list generating means As for the associated drug information, it is preferable to generate the state list using the time when the patient was input by the patient at the patient portable terminal when the drug was taken as the time of taking. is there.

  ADVANTAGE OF THE INVENTION According to this invention, it becomes possible to produce | generate the exact information regarding the condition of the patient who took the medicine, reducing a patient's burden.

It is a figure showing the whole medication support system composition in an embodiment of the invention. It is a functional block diagram which shows the structure of the medication assistance terminal in embodiment of this invention, a chemical | medical agent dispenser apparatus, and a patient portable terminal. It is a figure which shows the symptom keyword table in embodiment of this invention. It is a figure which shows the medication schedule information table in embodiment of this invention. It is a figure which shows the medication history information table in embodiment of this invention. It is a figure which shows the medicine symptom correspondence table in embodiment of this invention. It is a figure which shows the symptom list in embodiment of this invention. It is a flowchart which shows the production | generation process of the medication history information table in embodiment of this invention. It is a flowchart which shows the production | generation process of the symptom list in embodiment of this invention.

<System configuration>
The medication support system 1 according to the embodiment of the present invention includes a medication support terminal 2, a drug dispenser device 3, a patient portable terminal 4, a data server 5, a center terminal 6, and a hospital terminal, as shown in the overall system configuration diagram of FIG. 1. 7 and a pharmacy terminal 8.

  The medication support terminal 2 is a terminal that is installed in a patient's home and prompts the patient to take medication at an appropriate time. The drug dispenser device 3 is a device that discharges an appropriate drug to a patient based on an instruction from the medication support terminal 2. The patient portable terminal 4 is a terminal carried by the patient, and is a terminal for inputting that the patient has taken the medicine when going out. The data server 5 is a device that is installed in the data center and records various information. The center terminal 6 is installed in a management center, the hospital terminal 7 is installed in a medical institution such as a hospital, and the pharmacy terminal 8 is installed in a dispensing station.

  The devices constituting the medication support system 1 are connected by a communication network N, and various types of information are transmitted and received between the devices. As the communication network N, the Internet, a communication network of a mobile phone company, a telephone line, or the like is used. The communication network N may be realized by a wired connection or may be realized by a wireless connection.

  The medication support terminal 2 and the drug dispenser device 3 may be connected using short-range communication such as infrared communication or Bluetooth (registered trademark). Moreover, in this Embodiment, although the medication support terminal 2 and the chemical | medical agent dispenser apparatus 3 are comprised by the separate apparatus, they may be integrated.

  Hereinafter, with reference to FIG.1 and FIG.2, each structure of the medication support system 1 is demonstrated in detail.

<Pharmaceutical dispenser device 3>
The medicine dispenser device 3 is installed in a patient's home and stores a medicine prescribed by a doctor, and appropriately and appropriately supplies an appropriate amount of medicine to the patient. In the present embodiment, the drug dispenser device 3 provides a drug to the patient according to an instruction from the medication support terminal 2. As shown in the functional block diagram of FIG. 2, the medicine dispenser device 3 includes a medicine storage unit 31, a medicine discharge unit 32, and a communication unit 33. In addition, the medicine dispenser device 3 is not limited to the device in the present embodiment, and can appropriately provide one dose of medicine to the patient, and can grasp the name of the medicine provided, the amount of medicine, and the time provided. Anything is acceptable.

  The medicine storage unit 31 stores medicine prescribed by a doctor. In the present embodiment, as an example, the medicine storage unit 31 stores medicine for a predetermined period (for example, for two weeks). For example, a medicine for one dose is stored in advance in one case, and a case corresponding to a predetermined period is stored in the medicine storage unit 31. Hereinafter, a medicine in which a single dose of medicine is stored in a case is referred to as a “medicine cartridge”. For example, if a medicine to be taken in the morning, a medicine to be taken in the afternoon, and a medicine to be taken in the evening are prescribed, 42 medicine cartridges (2 weeks x 3 times in the morning, day and night = 42) are stored in the medicine. It is stored in the part 31.

  In the present embodiment, the medicine cartridges are stacked in the height direction and stored in the medicine container 31 in order from the medicine cartridge with the earliest timing of taking. Upon receiving an instruction to discharge the drug from the medication support terminal 2, the drug dispenser device 3 discharges the first drug cartridge from the bottom of the stacking order in the drug discharge unit 32 described later. Thereby, the medicine for one dose is provided to the patient in an appropriate dose order.

  The drug dispenser device 3 is not limited to the device in the present embodiment. For example, an apparatus is used in which an RFID is attached to a medicine cartridge, and a medicine cartridge containing an appropriate medicine is selected and discharged with reference to identification information (for example, ID) of the medicine cartridge read from the RFID. Also good. As another example, the medicine for one dose may be distributed within the medicine dispenser device 3 and discharged out of the device without using the medicine cartridge.

  The medicine discharge unit 32 appropriately discharges one dose of medicine out of the medicine dispenser device 3 from the medicines stored in the medicine storage unit 31. In the present embodiment, control is started in accordance with an instruction from the medication support terminal 2, and the medicine is discharged from the medicine storage unit 31.

  The medicine dispenser device 3 may be provided with a sensor that detects that the medicine has been discharged. In addition, a sensor that detects that the patient has taken out the provided medicine may be installed in the medicine dispenser device 3 instead of a sensor that detects medicine discharge. In addition, what is necessary is just to use a well-known sensor as a sensor which detects discharge | emission or taking-out of a medicine. When the discharge or removal of the drug is detected, the drug dispenser device 3 transmits the detected time as the discharge time to the medication support terminal 2 via the communication unit 33.

  Further, in this embodiment, when an instruction to discharge is not given even at the scheduled time for taking medicine, the medicine dispenser device 3 causes the medicine cartridge (to be taken out and to be discarded) Is stored in a disposal space provided in the apparatus. Thereby, the stacking order of the medicine cartridges in the medicine storage unit 31 is normalized. That is, the medicine cartridges are stacked in order of taking.

  The communication unit 33 transmits / receives various information to / from an external device. The communication unit 33 may be connected only to the medication support terminal 2 or may be connected to each device constituting the medication support system 1 via the communication network N to transmit / receive information.

<Medication support terminal 2>
The medication support terminal 2 is a terminal that is installed in a patient's home, prompts the patient to take medication at an appropriate time, and accepts a medicine discharge operation from the patient. The medication support terminal 2 is, for example, a tablet terminal, a smartphone, a mobile phone, or the like.

  The medication support terminal 2 has a function of inputting symptom information indicating a patient's symptoms when the patient feels unwell. Thereby, the medication support terminal 2 acquires the patient's symptoms as symptom information. The patient's symptom corresponds to an example of “patient state”, and the symptom information corresponds to an example of “state information”. As will be described later, for the symptom information input by the patient, the input time of the symptom, the name of the drug discharged by the drug dispenser device 3 (referred to as “drug name”), and the time of taking the drug are Associated with this, a symptom list is generated. The drug name corresponds to an example of “medicine information”, and the input time corresponds to an example of “state acquisition time”. The medication time is a time related to the medication, and may be the time when the patient actually took the medication, the time when the medication was discharged from the medication dispenser device 3, or the medication dispenser. The time when the medicine discharged from the apparatus 3 is taken out by the patient may be used. In addition, as a medicine taking time, a medicine taking time acquired from the patient portable terminal 4 to be described later may be used. The symptom list generation process will be described in detail later. The generated symptom list is transmitted to the data server 5 of the data center, and is recorded and managed by the data server 5. The symptom list is provided to each device constituting the medication support system 1 via the data server 5 as necessary.

  As shown in the functional block diagram of FIG. 2, the medication support terminal 2 includes an input unit 21 that receives input from a patient, a symptom acquisition unit 22 that acquires symptom information indicating an input symptom, and a storage unit that stores various types of information. 23, a discharge operation unit 24, an outing / discharge operation unit 25, a taking time association unit 26, a symptom list generation unit 27, a display unit 28, and a communication unit 29.

  The input unit 21 is an input button that is operated when the patient inputs symptoms to the medication support terminal. The input unit 21 may be a microphone that inputs a patient's voice.

  The symptom acquisition unit 22 acquires keywords related to symptoms from the input result of the input unit 21. In this Embodiment, the symptom acquisition part 22 acquires the keyword regarding a symptom based on operation of an input button (input part 21). The keywords are registered in advance in a symptom keyword table described later. Specifically, the patient operates the input button (input unit 21) to select a keyword from the symptom candidate group displayed on the display unit 28 based on the symptom keyword table, and the symptom acquisition unit 22 Get the keywords selected by the patient. Then, the symptom acquisition unit 22 associates the acquired keyword with the time when the keyword is input (referred to as “input time”), and outputs it to the dosing time association unit 26 described later.

  When a microphone is used as the input unit 21, the symptom acquisition unit 22 acquires a keyword by voice recognition. Specifically, the symptom acquisition unit 22 extracts a feature from the voice data input to the microphone (input unit 21), and uses the extracted feature as a voice feature of the keyword related to the previously stored symptom (the voice feature). Is stored in a symptom keyword table, for example, and a keyword corresponding to a voice feature similar to the extracted feature is acquired.

  When acquiring a keyword by voice recognition, the acquired keyword and the time (input time) when the keyword is input may be output to the dosing time association unit 26 described later in association with the voice data. Also, the input of voice data may be executed with some operation (for example, operation of the input button) as a trigger, or may be always executed so that the daily conversation of the patient can be collected.

  The storage unit 23 includes a semiconductor device such as a ROM (Read Only Memory) and a RAM (Random Access Memory), and a memory device such as a hard disk. The memory | storage part 23 memorize | stores various data, such as a program for performing each process in the medication assistance terminal 2, setting data, and the produced | generated data. For example, the storage unit 23 stores a symptom keyword table, a medication schedule information table, a medication history information table, and a medication symptom correspondence table. Hereinafter, these tables will be described in detail.

  The symptom keyword table is a list of keywords relating to symptoms prepared in advance as shown in FIG. When a keyword is acquired by voice recognition, the voice feature is also registered in the symptom keyword table. The symptom keyword table may be prepared according to the patient's disease name or may be prepared for each patient. In this case, a patient ID for identifying the patient is associated with the symptom keyword table. As another example, the symptom keyword table may be a common table for a plurality of patients regardless of the disease name.

  As shown in FIG. 4, the medication schedule information table is information in which the name of a drug taken by a patient and the scheduled medication time are associated with each other. The medication schedule information table is prepared for each patient and is stored in advance in the storage unit 23 in association with the patient ID. The medication schedule information table may be stored in the data server 5 and downloaded from the data server 5 to the medication support terminal 2.

  As shown in FIG. 5, the medication history information table includes a scheduled medication time, a name of the medication discharged by the medication dispenser device 3 (medicine name), a medication state, a delivery time, and a medication medication time. Associated information. The discharge time is the time when the drug is discharged from the drug dispenser device 3 or the time when the patient takes out the drug from the drug dispenser device 3. The medication history information table is generated for each patient and is associated with the patient ID. The medication history information table corresponds to an example of a “history list”.

  When the medicine is discharged from the medicine dispenser device 3 in accordance with an instruction from the discharge operation unit 24 described later, the medication state is set to “normal”, and the medicine ejection time is registered in the medication history information table as the medication time. When the medicine is dispensed from the medicine dispenser device 3 in accordance with an instruction from the outing / dispensing operation unit 25 to be described later, the taking state is set to “going out” and the taking time inputted at the patient portable terminal 4 is registered in the taking history information table. Is done. When the medicine is not discharged at the scheduled time of taking medicine, the taking state is set to “do not take” and the discharge time and the taking time are not registered.

  The medication history information table is not limited to that shown in FIG. 5, and other information may be stored. For example, as information other than the above, the amount of the provided drug, the patient's symptoms, information indicating that the patient's symptoms have been improved by taking the drug, and the like may be stored.

  As shown in FIG. 6, the drug symptom correspondence table is information in which a keyword related to a symptom and a drug name (drug name) related to the symptom are associated with each other. The association between the symptom and the drug name is performed based on a symptom (symptom corresponding to a side effect) that may appear when the patient takes the drug. For example, when a patient takes Drug A, the side effects of “congestive heart failure” may occur, and the symptoms are “suffering when moving”, “easy to get tired”, “foot is swollen”, The keywords “suddenly gained weight” and “cough and pink sputum” are associated with the drug A, respectively.

  Further, in the present embodiment, not only side effects but also symptoms that may appear because there is no drug effect (symptoms that could not be suppressed by the drug) may be further associated with the drug symptom correspondence table as “unsuccessful symptoms”. . For example, the drugs D and E are associated with “unsuccessful symptoms”. For example, although the drug D is a drug for treating “edema”, the edema symptom “swelling” may appear without being suppressed because the drug has no effect. Therefore, in the drug symptom correspondence table, the symptom keyword “swell” and the symptom name “edema” are associated with the drug D.

  The drug symptom correspondence table is prepared in advance and stored in the storage unit 23. The drug symptom correspondence table may be prepared for each patient according to the patient's disease name. In this case, the patient ID is associated with the drug symptom correspondence table. As another example, the drug symptom correspondence table may be a common table for a plurality of patients regardless of the disease name. The drug symptom correspondence table corresponds to an example of a “drug state association list”.

  Returning to FIG. 2, the medication support terminal 2 will be described.

  The discharge operation unit 24 is an operation unit that is operated by a patient to acquire a medicine to be taken at the scheduled medication time. The discharge operation unit 24 includes, for example, a discharge operation button and a discharge operation control unit.

  The discharge operation button may be an icon displayed on the display unit 28 such as a touch panel monitor, or may be a physical button.

  The discharge operation control means refers to the medication schedule information table (see FIG. 4), and when the scheduled medication time arrives, the operation of the discharge operation button becomes possible. For example, the discharge operation button can be operated until a predetermined time elapses from the scheduled medication time. Alternatively, when the scheduled medication time arrives, the discharge operation control means outputs an instruction to the drug discharge unit 32 via the communication unit 29 so that the drug discharge unit 32 of the drug dispenser device 3 can be controlled. May be.

  When the discharge operation button is operated by the patient, the discharge operation control means outputs an instruction to the drug discharge unit 32 of the drug dispenser device 3 so that the drug is discharged from the drug dispenser device 3.

  When the discharge operation button is operated, the discharge operation control means registers the time when the medicine is discharged (discharge time) and the name of the discharged medicine (name of the medicine) in the medication history information table. That is, the medicine name is associated with the discharge time in response to the medicine dispenser device 3 providing the medicine. Further, the discharge operation control means sets the discharge time to “dosing time”, and registers the taking time and the taking state “normal” in the taking history information table. Here, the drug name is acquired by referring to the medication schedule information table stored in the storage unit 23. The discharge operation control means corresponds to an example of “history list generation means”.

  If the discharge operation button is not operated even after a predetermined time (for example, 30 minutes) has elapsed from the scheduled medication time, the discharge operation control means refers to the medication schedule information table and the name of the drug that has not been discharged (drug name) Correspondingly, the administration state “not taking” is registered in the medication history information table. Then, the discharge operation control means controls the drug discharge unit 32 of the drug dispenser device 3. Specifically, the discharge operation control means outputs a discard instruction to the drug discharge unit 32 of the drug dispenser device 3 via the communication unit 29.

  The medicine discharge unit 32 of the medicine dispenser device 3 detects by the sensor that the medicine has been discharged or the patient has taken out the discharged medicine, and the discharge operation control means acquires the detection result. Then, the medication history information table stored in the storage unit 23 may be registered in association with the name (medicine name) of the discharged medicine, with the discharge time as “dosing time”. The medicine dispenser device 3 may output the name of the discharged medicine to the medication support terminal 2.

  The outing and discharging operation unit 25 is an operation unit that is operated by a patient to obtain in advance a medicine to be taken at the place of going out. The outing / discharging operation unit 25 includes, for example, an outing / discharging operation button and an outing / discharging operation control means.

  The out / in operation button is a button that can be operated even before the scheduled medication time. The outing / ejecting operation button may be an icon displayed on the display unit 28 such as a touch panel monitor, or may be a physical button. When the outing / exhausting operation button is operated by the patient, the outing / extracting control means outputs an instruction to the medicine discharging unit 32 of the medicine dispenser device 3 so that the medicine is discharged from the medicine dispenser device 3.

  In addition, when the outing / discharging operation button is operated, the outing / discharging operation control means displays the name of the medicine (medicine name) discharged from the medicine dispenser device 3 and the time when the outing / discharging operation button is operated. Register with. Here, the drug name is acquired by referring to the medication schedule information table stored in the storage unit 23. Further, the outing and discharging operation control means registers the taking state “going out” in the medication history information table. Note that the out-and-out discharge operation control means corresponds to an example of “history list generation means”. Also, the “going out” taking state corresponds to an example of “outing information”.

  Further, when the medicine is discharged from the medicine dispenser device 3 by the going-out discharge operation, the out-going discharge control means refers to the medication schedule information table stored in the storage unit 23 and via the communication unit 29, the patient portable terminal 4, a notification instruction signal including information such as scheduled medication time of the drug is transmitted. The patient portable terminal 4 that has received the notification instruction signal displays a notification prompting the patient on the display unit 42 when the scheduled time for taking the drug arrives. Accordingly, when the patient who has taken the medicine operates the patient portable terminal 4 to input that the medicine has been taken, the going-out discharge operation control means displays the signal that the medicine has been taken and the time that the medicine has been taken. (Manually entered medication time) is obtained from the patient portable terminal 4, and the medication time information is stored in the medication history information table in association with the name (medicine name) of the medicine discharged by the outing operation, with the time as “medical time”. sign up.

  In addition, the outing and discharging operation control means refers to the dosing schedule information table when no signal of “taken” is received from the patient portable terminal 4 even after a predetermined time (for example, 30 minutes) has elapsed from the scheduled dosing time. Then, the medication state “not-taken” is registered in the medication history information table in association with the name (medicine name) of the medication discharged in the out-of-door discharge operation.

  In addition, when the outing and discharging operation is performed, the outing and discharging operation control means is not limited to the mode of manually inputting the dosing time on the patient portable terminal 4, and obtains the scheduled medication time in the dosing schedule information table, The scheduled medication time may be registered in the medication history information table as a medication time.

  When the information is added by the discharge operation control means or the outing operation control means, the dose history information table is transmitted to the data server 5 via the communication unit 29 and stored.

  The taking time association unit 26 associates the symptom information (acquired keyword) input by the patient, the input time of the symptom information, the name of the medicine taken (drug name), and the taking time of the medicine.

  When a symptom-related keyword is acquired by the symptom acquisition unit 22, the dosing time association unit 26 refers to the drug symptom correspondence table (see FIG. 6) stored in the storage unit 23 and corresponds to the acquired keyword. The name of the medicine to be acquired is acquired, and referring to the medication history information table (FIG. 5) stored in the storage unit 23, the medication time (the latest medication time) of the medication is obtained. The latest dosing time is the latest taking time of the drug going back from the input time. Then, the medication time association unit 26 associates the keyword (symptom), the input time, the drug name, and the medication time, and outputs them to the symptom list generation unit 27. Here, the dosing time association unit 26 may calculate an elapsed time (time difference) from the dosing time to the input time, and associate the elapsed time with a keyword or the like.

  The symptom list generation unit 27 generates a symptom list by associating the “keyword (symptom)”, “input time”, “drug name”, and “dose time” associated with each other by the dose time association unit 26, and the symptom list. The list is stored in the storage unit 23. The symptom list is also associated with the patient ID. In addition, the symptom list generation unit 27 transmits the symptom list to the data server 5 via the communication unit 29. The symptom list generation unit 27 corresponds to an example of a “state list generation unit”, and the symptom list corresponds to an example of a “state list”.

  If the symptom is not clearly related to the side effect from the relationship between the keyword input time and the dose time, for example, if the time difference between the input time and the dose time is greater than or equal to a predetermined time, the symptom list generator 27 The input time or the like may not be added to the symptom list.

  In addition, when the relationship between the input time and the taking time is high, for example, when the time difference between the input time and the taking time is less than a predetermined time, the symptom list generating unit 27 is displayed so as to stand out from the other items. May be changed. Specifically, in the drug symptom correspondence table (see FIG. 6), a time during which a side effect is likely to occur is set in advance as a monitoring time for each drug name and each symptom (for each keyword). Depending on whether or not the input time is within the monitoring time, whether to add to the display mode or the symptom list may be determined.

  FIG. 7 shows an example of a symptom list. In the symptom list, “patient ID”, “symptom (keyword)”, “input time”, “drug name”, “dose time”, and “elapsed time” are associated.

  Referring to the symptom list, it can be seen that after the patient takes the drug B, the side effect symptom “vertigo” appears. Further, for the medicine B (2015/12/1 12:36) taken out for going out, the associated “taking time” is not the “discharge time” shown in FIG. It can be seen that manually entered “time of taking” is adopted.

  In addition, referring to the symptom list, it can be seen that symptoms that should be suppressed by the drug E appear after the patient took the drug E. It is assumed that the medicine E is a medicine newly prescribed by a doctor after the medicine prescribed for the first two weeks has run out. Thus, information is added to the symptom list while the patient is taking medication.

  Each time a new symptom is added to the symptom list, the contents of the symptom list stored in the storage unit 23 are updated, and the updated symptom list is transmitted to the data server 5 via the communication unit 29.

  As an example different from the above example, when a symptom-related keyword is acquired by the symptom acquisition unit 22, the medication time association unit 26 refers to a medication history information table (FIG. 5) stored in the storage unit 23. Then, the dose time associated as the latest time of the input time and the drug name associated with the dose time may be acquired. Also in this case, the taking time association unit 26 associates the keyword (symptom), the input time, the drug name, and the taking time, and outputs them to the symptom list generation unit 27, and the symptom list generation unit 27 associates these pieces of information. To generate a symptom list. The latest time is the most recent dose time going back from the input time. There is a possibility that the medicine taken at the time immediately before the input time is a medicine that develops the input symptom. Therefore, even if the drug corresponding to the symptom is not associated in the drug symptom correspondence table by generating the symptom list by acquiring the drug name and taking time from the medication history information table, It is possible to generate a symptom list including the names of drugs that may develop symptoms (drug names) and the time of taking them.

  As yet another example, the medication time association unit 26 refers to the medication history information table (FIG. 5) stored in the storage unit 23 and is associated with a time within a predetermined time from the input time. You may acquire the time and the medicine name linked | related with the taking time. Also in this case, the taking time association unit 26 associates the keyword (symptom), the input time, the drug name, and the taking time, and outputs them to the symptom list generation unit 27, and the symptom list generation unit 27 associates these pieces of information. To generate a symptom list. There is a possibility that a drug taken within a predetermined time from the input time is a drug that develops the input symptom. Therefore, even if the drug corresponding to the symptom is not associated in the drug symptom correspondence table by generating the symptom list by acquiring the drug name and taking time from the medication history information table, It is possible to generate a symptom list including the names of drugs that may develop symptoms (drug names) and the time of taking them.

  The display unit 28 includes a monitor that displays various information to be provided to the patient, such as a symptom list and a notification for prompting medication, and a display control unit that controls display on the monitor. The monitor may be a touch panel type monitor.

  When the patient operates the medication support terminal 2 at a timing when he / she wants to check the symptom list, the display control means reads out the symptom list stored in the storage unit 23 and displays it on the monitor.

  Moreover, the display control means will display the content on a monitor, if guidance information is received from each apparatus of the medication assistance system 1. FIG. For example, the display control means displays information such as an onset rate and frequent elapsed time described later on the monitor.

  In addition, the display control means refers to the medication schedule information table stored in the storage unit 23, and displays a notification prompting the patient to take medication at the scheduled medication time. Note that a speaker may be installed in the medication support terminal 2 so that a sound prompting medication is generated from the speaker.

  In addition, when the discharge operation unit 24 does not perform the discharge operation after the notification prompting the medication is displayed, the display control unit repeatedly displays the notification prompting the medication on the monitor for a predetermined time (for example, 30 minutes). You may let them.

  The communication unit 29 transmits and receives various types of information to and from external devices (for example, each device constituting the medication support system 1 such as the drug dispenser device 3, the patient portable terminal 4, and the center terminal 6).

  The symptom acquisition unit 22, the taking time association unit 26, and the symptom list generation unit 27 include at least one processor such as a CPU (Central Processing Unit), a DSP (Digital Signal Processor), an MCU (Micro Control Unit), and its peripheral circuits. Consists of.

<Patient mobile terminal 4>
The patient portable terminal 4 is a terminal that is carried when the patient goes out and inputs that the medicine has been taken. In the case where the medication support terminal 2 is a portable terminal, the patient portable terminal 4 may be incorporated in the medication support terminal 2. The patient portable terminal 4 is, for example, a tablet terminal, a smartphone, a mobile phone, or the like.

  As shown in the functional block diagram of FIG. 2, the patient portable terminal 4 includes an input unit 41, a display unit 42, a dose time output unit 43, a storage unit 44, and a communication unit 45.

  The input unit 41 is a physical button used by the patient to operate the patient portable terminal 4. The input unit 41 is used, for example, to input that the patient has taken a medicine taken out for going out. When a touch panel monitor is used as the display unit 42, the input unit 41 and the display unit 42 may be integrated.

  Further, the input unit 41 may have a function of inputting a symptom like the medication support terminal 2. In this case, the patient portable terminal 4 may transmit the content input from the input unit 41 to the symptom acquisition unit 22 of the medication support terminal 2 via the communication unit 45.

  The display unit 42 is configured to include a monitor that displays a notification or the like that prompts the patient to take a medicine, and display control means that controls display on the monitor.

  When the display control means receives the notification instruction signal from the outing operation control means (outing discharge operation section 25) of the medication support terminal 2 via the communication section 45, the display control means informs the patient when the scheduled medication time arrives based on the notification instruction signal. On the other hand, a notification prompting the user to take the medicine is displayed on the monitor. In addition, a speaker may be installed in the patient portable terminal 4 and a sound for prompting medication may be generated from the speaker.

  The display control means may acquire a symptom list from the medication support terminal 2 via the communication unit 45 and display the symptom list on a monitor.

  The taking time output unit 43 includes at least one processor such as a CPU, DSP, MCU, and its peripheral circuits. When the input unit 41 is operated to input that the medicine has been taken, the medication time output unit 43 receives information indicating “medicine taken” and “manual” to the medication support terminal 2 via the communication unit 45. “Input time of taking (time when it is input that the medicine has been taken)” is transmitted. At this time, in the medication support terminal 2, the medication time output unit 43 transmits the medication taken via the communication unit 45 so that the manually entered medication time is associated with other information in the medication history information table. Information such as a name (medicine name) and scheduled medication time is also added and transmitted to the medication support terminal 2. In order to facilitate the association, the medication history items may be managed by ID.

  The storage unit 44 stores information included in the notification instruction signal transmitted from the medication support terminal 2. The memory | storage part 44 memorize | stores the chemical | medical agent name which needs notification, and its medication scheduled time, for example. In addition, the storage unit 44 stores the time when the patient has input the fact that the medicine has been taken in association with the name of the medicine that needs to be included in the notification instruction signal. The patient portable terminal 4 may acquire the medication schedule information table from the medication support terminal 2 and store it in the storage unit 44. Further, the storage unit 44 may store a symptom list acquired from the medication support terminal 2.

  The communication unit 45 transmits / receives various information to / from an external device (for example, each device configuring the medication support system 1).

<Data server 5>
The data server 5 is installed in the data center as shown in the overall system configuration diagram of FIG.

  The data center is configured to include one or a plurality of devices, and receives various types of information from each device constituting the medication support system 1 and stores them in the data server 5, or stores the stored information according to requests. Or send it to the device. As a result, the information stored in the data server 5 is shared between the devices constituting the medication support system 1 via the communication network N.

  The data server 5 stores the symptom list generated by the medication support terminal 2. At this time, the symptom list for each patient is managed by the patient ID. When the data server 5 receives the updated symptom list from the medication support terminal 2, the data server 5 updates the symptom list associated with the same patient ID as the patient ID associated with the symptom list. Further, the data server 5 stores the medication history information table for each patient and updates the medication history information table for each patient.

<Center terminal 6>
The center terminal 6 is installed in the management center as shown in the overall system configuration diagram of FIG.

  The management center centrally manages medication support for patients. A supervisor who has medical knowledge is stationed at the management center, and the supervisor responds to various consultations from patients and takes appropriate measures in cooperation with hospitals, dispensing pharmacies, and the like.

  The center terminal 6 is connected to each device constituting the medication support system 1 via the communication network N, and exchanges various data and instructions regarding correspondence.

  In the management center, it is also possible to communicate with patients, doctors, pharmacists and the like through a telephone line. The contact information for patients, hospitals, and the like is managed by, for example, the data server 5 of the data center.

  In the present embodiment, the center terminal 6 includes a display unit 61, a symptom list analysis unit 62, and a communication unit 63.

  The display unit 61 includes a monitor that displays various types of information and a display control unit that controls display on the monitor. For example, when the monitor operates the center terminal 6 at a timing when the symptom list is desired to be displayed, the display control unit acquires the symptom list from the data server 5 via the communication unit 63 and displays the symptom list on the monitor. .

  The symptom list analysis unit 62 calculates information that can be used for dealing with symptoms by analyzing the symptom list. For example, as the information, the symptom list analysis unit 62 calculates the incidence rate of symptoms and the frequent elapsed time from the time of taking (a time zone in which symptoms appear in the patient after taking). The symptom list analysis unit 62 includes at least one processor such as a CPU, DSP, or MCU and its peripheral circuits. The symptom list analysis unit 62 corresponds to an example of “analysis means”.

  The symptom list analysis unit 62 may calculate the symptom onset rate and frequent elapsed time in the patient by analyzing the symptom list of one patient (for example, a designated patient). By analyzing the symptom list, the symptom incidence and frequent elapsed time in a plurality of patients may be calculated.

  When obtaining the symptom onset rate, the symptom list analysis unit 62 refers to a medication history information table stored in the data server 5, for example, and obtains a symptom list of a patient who has taken the medicine to be calculated. Get from. Then, the symptom list analysis unit 62 divides the number of patients whose calculation target symptom is included in the symptom list by taking the calculation target drug by the number of patients who have taken the calculation target drug. Calculate the incidence as a percentage. Note that the medicine or symptom to be calculated is designated by a monitor, a doctor, a pharmacist, or the like using the center terminal 6, the hospital terminal 7, the pharmacy terminal 8, or the like. Further, not only a single type of medicine is a calculation target, but a combination of a medicine and a medicine may be a calculation target.

  For example, in the case of calculating the incidence rate of “vertigo” caused by the medicine B, the number of patients whose medicine B is included in the medication history information table is 100, and “vertigo” is listed in the symptom list of 9 of them. "Is associated, the incidence is 9 percent.

  When determining the frequent elapsed time, the symptom list analysis unit 62 acquires from the data server 5 a symptom list of a patient who has taken the calculation target drug and has developed the calculation target symptom. Then, the symptom list analysis unit 62 acquires the elapsed time from each symptom list, assumes a normal distribution of the appearance frequency of symptoms, and calculates, for example, an average value ± 2 standard deviation as the frequent occurrence time of the symptom.

  For example, when calculating the frequent elapsed time of “vertigo” generated by the drug B, if the average value is 2 hours and 1 minute and the 2 standard deviation is 47 minutes, 1 hour and 14 minutes from taking the drug B Between 2 hours 48 minutes is a frequent time zone.

  The calculated incidence rate and frequent time zone are displayed on the display unit 61 of the center terminal 6 or transmitted to the hospital terminal 7 and the pharmacy terminal 8 via the communication unit 63 and displayed on the respective display units. This information is confirmed by monitoring personnel, doctors, pharmacists, etc., and is used for responding to patients, changing prescription contents, taking medication instructions, taking measures against drugs, and the like. The calculated information may be stored in the data server 5.

  Moreover, you may make it notify with respect to a patient via the medication support terminal 2 or the patient portable terminal 4 by making the calculated incidence rate and frequent time zone into description (guidance information) of a symptom.

  In the present embodiment, the symptom list analysis unit 62 is provided in the center terminal 6, but not limited to this, the symptom list analysis unit 62 may be provided in the medication support terminal 2 or the medication support system 1 It may be provided in another device that constitutes.

  The communication unit 63 transmits and receives various types of information to and from an external device (for example, each device constituting the medication support system 1).

<Hospital terminal 7>
The hospital terminal 7 is installed in a hospital as shown in the overall system configuration diagram of FIG. The hospital terminal 7 is a terminal for displaying various information such as a symptom list, a symptom occurrence rate, and a frequent elapsed time, and a doctor confirming the information. The hospital terminal 7 includes a display unit 71 and a communication unit 72.

  The display unit 71 includes a monitor that displays various types of information, and a display control unit that controls display on the monitor. For example, when the doctor operates the hospital terminal 7 at a timing when the symptom list is to be displayed, the display control unit acquires the symptom list from the data server 5 via the communication unit 72 and displays the symptom list on the monitor.

  The communication part 72 transmits / receives various information between external apparatuses (for example, each apparatus which comprises the medication support system 1).

<Pharmacy terminal 8>
The pharmacy terminal 8 is installed in a dispensing pharmacy as shown in the overall system configuration diagram of FIG. The pharmacy terminal 8 is a terminal for displaying various information such as a symptom list, a symptom onset rate, and a frequent elapsed time, and a pharmacist confirming the information. The pharmacy terminal 8 includes a display unit 81 and a communication unit 82.

  The display unit 81 includes a monitor that displays various types of information, and a display control unit that controls display on the monitor. For example, when the pharmacist operates the pharmacy terminal 8 at a timing when the symptom list is desired to be displayed, the display control unit acquires the symptom list from the data server 5 via the communication unit 82 and displays the symptom list on the monitor.

  The communication part 82 transmits / receives various information between external apparatuses (for example, each apparatus which comprises the medication support system 1).

  In the present embodiment, the symptom list displayed on the medication support terminal 2 or the patient portable terminal 4 may be different from the symptom list displayed on other devices. For example, when voice data is included in the symptom list generated by the medication support terminal 2, when the symptom list is displayed at the center terminal 6, the hospital terminal 7, or the pharmacy terminal 8, the voice data is excluded. The symptom list may be displayed on these terminals. Specifically, the center terminal 6, the hospital terminal 7, or the pharmacy terminal 8 acquires the symptom list from which the voice data is excluded from the data server 5 and displays it.

  In the medication support terminal 2, items that the patient does not want to report to the doctor or pharmacist may be excluded from the symptom list. For example, by operating the medication support terminal 2, the patient can select a symptom list item to be transmitted to the center terminal 6, the hospital terminal 7, or the pharmacy terminal 8. As a result, a symptom list including only the item selected by the patient is generated, and the symptom list is transmitted to the center terminal 6 and displayed. For example, if a daily conversation that is not related to a symptom is included in the symptom list by voice recognition, the voice data related to such a daily conversation is selected as an item that you do not want to report, and the voice data is excluded. A list is generated and sent.

  Hereinafter, the operation of the medication support system 1 in the present embodiment will be described. First, with reference to FIG. 8, a process for generating a medication history information table will be described.

  The medication support terminal 2 refers to the medication schedule information table stored in advance in the storage unit 23, and determines whether or not the scheduled medication time has arrived (S101). When the scheduled medication time has arrived (S101, YES), the medication support terminal 2 displays a notification for prompting medication on the display unit 28 (S102). At this time, the discharge operation unit 24 is in an operable state.

  Thereafter, when the patient performs a discharge operation using the discharge operation unit 24 (S104, YES), a discharge instruction signal is transmitted from the medication support terminal 2 to the drug dispenser device 3 via the communication unit 29, and the drug dispenser. A predetermined medicine is discharged from the device 3 (S105). Then, the medication support terminal 2 stores the name of the medicine (medicine name) discharged by the medicine dispenser device 3 in the medication history information table stored in the storage unit 23, and the time when the discharge operation is performed. The medication time is stored in the medication history information table (S106). In addition, the medication support terminal 2 stores the medication status as “normal” in the medication history information table (S106).

  On the other hand, when the discharge operation is not performed by the patient (S104, NO), the medication support terminal 2 repeats the display prompting the medication on the display unit 28 until a predetermined time (for example, 30 minutes) elapses from the scheduled medication time ( S107, NO).

  When a predetermined time has elapsed from the scheduled medication time (S107, YES), the medication support terminal 2 stores the name of the medication scheduled to be discharged (medicine name) in the medication history information table stored in the storage unit 23. At the same time, the medication state is stored in the medication history information table as “not taking” (S108). In addition, the medication support terminal 2 transmits a discard instruction signal to the drug dispenser device 3.

  When the patient performs the out-and-out discharge operation using the out-and-out discharge operation unit 25 (S103, YES), a signal is transmitted from the medication support terminal 2 to the drug dispenser device 3 via the communication unit 29, and the drug dispenser A predetermined medicine is discharged from the device 3 (S109). Then, the medication support terminal 2 displays the name of the discharged medicine (medicine name), the time when the out-going discharge operation was performed, and the medication state “going out” in the medication history information table stored in the storage unit 23. Store (S110).

  At the same time, the medication support terminal 2 transmits a notification instruction signal including the scheduled medication time of the medicine discharged for going out to the patient portable terminal 4 via the communication unit 29 (S111). As a result, in the patient portable terminal 4, the scheduled medication time included in the notification instruction signal is stored in the storage unit 44, and when the scheduled medication time arrives, a notification for prompting medication is displayed on the display unit 42.

  When the patient takes the medicine taken out when he / she goes out and operates the input unit 41 of the patient portable terminal 4 to input that he / she has taken the medicine (S112, YES), the patient portable terminal 4 The time when the fact of taking is input is stored in association with the drug name, and the information is transmitted to the medication support terminal 2 via the communication unit 45. Upon receiving the information, the medication support terminal 2 stores the time inputted by the patient as the medication time of the medication name whose medication information is “going out” in the medication history information table (S113).

  Further, the medication support terminal 2 does not receive a signal indicating that the medication has been taken from the patient portable terminal 4 even after a predetermined time (for example, 30 minutes) has elapsed from the scheduled medication time (S112, NO, S114, YES). In association with the discharged medicine name, the medication state is stored in the medication history information table as “not taken” (S115).

  Next, a symptom list generation process will be described with reference to FIG.

  When a symptom to be worried is input by the patient at the medication support terminal 2 (S201, Yes), the medication support terminal 2 associates the input symptom with the input time (S202).

  Next, the medication support terminal 2 determines whether or not the input symptom is included in the drug symptom correspondence table stored in the storage unit 23 (S203). When the input symptom is included in the drug symptom correspondence table (S203, YES), the medication support terminal 2 acquires the drug name corresponding to the input symptom from the drug symptom correspondence table (S204). ). If there is a medication history of the corresponding medicine, that is, if a medication history of the corresponding medicine is stored in the medication history information table (YES in S205), the medication support terminal 2 The most recent dose time is acquired from the medication history information table. In addition, the medication support terminal 2 calculates the elapsed time from the dose time to the input time.

  The medication support terminal 2 associates the input symptom with the input time and the drug name (S206), and further associates the medication time with the elapsed time to generate a symptom list (S207). The medication support terminal 2 stores the symptom list in the storage unit 23 and transmits the symptom list to the data server 5 of the data center (S208). The symptom list is updated.

  When the inputted symptom is not registered in the drug symptom correspondence table (S203, NO), or when the corresponding drug is not taken by the patient (when the medication history is not stored in the medication history information table) ( (S205, NO), the process returns to step S201. In this case, the medication support terminal 2 may store only the symptom and the time when the information is input in the symptom list.

  As described above, according to the medication support system 1 in the present embodiment, the patient simply operates the medication support terminal 2 and inputs a symptom, and the symptom, the input time of the symptom, and the possibility of developing the symptom. A symptom list in which the name of a certain drug (drug name) and the time of taking the drug are associated is generated. The generated symptom list is provided to patients and medical personnel. The symptom list is used, for example, as information for determining the presence or absence of side effects. According to the present embodiment, it is possible to provide medical staff with highly accurate information that can be used for dealing with side effects while reducing the burden on the patient. That is, since the symptom list is generated by using the information that the medicine dispenser device 3 has, the medication schedule information table, the medication history information table, the medication symptom correspondence table, etc., the patient can take the name of the medication taken and the medication time Etc. are memorized one by one, and there is no need to input them. Therefore, it is possible to reduce the burden on the patient. In addition, since incorrect information (for example, drug name, medication time, etc.) is not input by the patient, a highly accurate symptom list can be generated.

  In addition, by calculating the onset rate of symptom and the frequent appearance time zone, it is possible to provide the medical staff with the frequent occurrence timing and onset rate of side effects based on the record information. This makes it possible to use these pieces of information for selecting a prescription drug or for dealing with a side effect or the like in the patient.

  In addition, when the medicine is discharged for going out, the time inputted at the patient portable terminal 4 is used as the taking time, and the symptom list is generated. This makes it possible to generate a symptom list using an accurate dosing time even when the patient has acquired a medicine for going out in advance. Therefore, it is possible to allow prior acquisition of the medicine. Further, even when the patient is taking the medicine on the go, a symptom list is generated using a medication history information table or the like. Therefore, the patient does not need to remember the drug name. Since the patient does not need to enter the name of the drug when taking it, it is possible to generate a symptom list based on accurate information even if the patient forgets the name of the drug taken on the go Become.

  DESCRIPTION OF SYMBOLS 1 Medication support system, 2 Medication support terminal, 3 Drug dispenser device, 4 Patient portable terminal, 5 Data server, 6 Center terminal, 7 Hospital terminal, 8 Pharmacy terminal, 21,41 Input part, 22 Symptom acquisition part, 23,44 Storage unit, 24 discharge operation unit, 25 going out discharge operation unit, 26 dose time association unit, 27 symptom list generation unit, 28, 42, 61, 71, 81 display unit, 29, 33, 45, 63, 72, 82 communication Part, 31 medicine storage part, 32 medicine discharge part, 43 dosing time output part, 62 symptom list analysis part.

Claims (6)

A drug dispenser device for providing a drug to a patient;
A medication support terminal for obtaining the status of the patient as status information;
In response to providing the medicine by the medicine dispenser device, history list generating means for generating a history list by associating the time of providing the medicine with the medicine information indicating the provided medicine as a taking time;
In response to the acquisition of the state information by the medication support terminal, the history list is used to associate the drug information, the time of taking, the state information, and the state acquisition time of acquiring the state information. State list generating means for generating a state list;
Storage means for storing a medicine state association list in which the medicine information and a state that can appear in the patient by taking the medicine are associated;
Have
The state list generation means generates the state list using the drug information associated with the patient state indicated by the state information in the drug state association list.
A medication support system characterized by that. A drug dispenser device for providing a drug to a patient;
A medication support terminal for obtaining the status of the patient as status information;
In response to providing the medicine by the medicine dispenser device, history list generating means for generating a history list by associating the time of providing the medicine with the medicine information indicating the provided medicine as a taking time;
In response to the acquisition of the state information by the medication support terminal, the history list is used to associate the drug information, the time of taking, the state information, and the state acquisition time of acquiring the state information. State list generating means for generating a state list;
Have
The state list generating means uses the time taken immediately before the state acquisition time among the time taken included in the history list, and the drug information associated with the time taken for taking the state list. Generate,
A medication support system characterized by that. A drug dispenser device for providing a drug to a patient;
A medication support terminal for obtaining the status of the patient as status information;
In response to providing the medicine by the medicine dispenser device, history list generating means for generating a history list by associating the time of providing the medicine with the medicine information indicating the provided medicine as a taking time;
In response to the acquisition of the state information by the medication support terminal, the history list is used to associate the drug information, the time of taking, the state information, and the state acquisition time of acquiring the state information. State list generating means for generating a state list;
Have
The state list generation means uses a dosing time within a predetermined time retroactively from the state acquisition time among the dosing times included in the history list, and the drug information associated with the taking time, Generating the state list;
A medication support system characterized by that. In the medication support system according to any one of claims 1 to 3 ,
Said have you state list, based on the number of the status information indicating the status of the calculation target associated with the drug information indicative of medicament to be calculated, further analysis means for calculating the rate of occurrence of the state of the calculation target Have
A medication support system characterized by that. In the medication support system according to any one of claims 1 to 3 ,
Analyzing the time difference between the dose time associated with the status list and the status acquisition time, and further comprising an analysis means for outputting the analysis result;
A medication support system characterized by that. In the medication support system according to any one of claims 1 to 5 ,
A patient portable terminal for inputting that at least the patient has taken the medicine;
The medicine dispenser device further provides the medicine for the patient to take on the go according to a predetermined operation,
The history list generation means further associates the outing information with the drug information of the drug provided to be taken on the go.
For the drug information associated with the outing information, the state list generation unit uses, as the dosing time, the time when the patient input the patient using the patient portable terminal when taking the drug. To generate the state list,
A medication support system characterized by that.

Images