JP2013031638A - Label, method for manufacturing label, program, management system, and management method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide: a label to be stuck to a blister pack, having a function for managing information on the history of medication for a patient; a method for manufacturing the label; a program for the label; a management system; and a management method.SOLUTION: The label 1 includes a base label 110, a time logger 120 and a cover label 130. A circuit is formed in the base label 110, and the circuit is broken when a medicament is discharged from each pocket in a PTP sheet 2 to which the label 1 is stuck. The time logger 120 is disposed in such a way as to be joined with a selvage part 203 of the PTP sheet 2 to detect the change of impedance values caused by the broken circuit, to store information on the time of the change, and to radio-transmit the information, etc.

Description

  The present invention relates to a label, a label manufacturing method, a program, a management system, and a management method.

  In recent years, information management such as traceability in various products has become important. In order to realize such a requirement, IC tag technology is often used. For example, Patent Document 1 below discloses a technique that enables tracing of information related to a drug even after an IC tag is added to a container that stores the drug and the drug reaches the patient's hand.

JP 2005-211601 A

  In medical care, if a patient properly takes a prescribed medicine in a predetermined amount at a predetermined time, it greatly affects whether or not a therapeutic effect can be obtained correctly. Therefore, in the medical field, it is desirable to be able to manage patient medication history information. It would be extremely useful for appropriate medical treatment if a product or system capable of managing information on the history of medication time of a patient can be realized by effectively utilizing IC tag technology.

  Therefore, the problem to be solved by the present invention is that a label affixed to a blister package and used for managing history information of a patient's medication time, a manufacturing method of the label, a program related to the label, a management system, and management It is to provide a method.

  In order to solve the above-described problems, a label according to the present invention includes a plurality of pocket portions formed to be aligned vertically and horizontally so as to accommodate a drug, and an ear portion that is a peripheral region where the pocket portions are not formed. A label affixed to a blister package comprising: an adhesive layer, and affixed by the adhesive layer to a surface of the blister package on the side from which the medicine contained in the pocket portion is discharged A base label having no electrical conductivity, and a circuit part that is formed so that a current flows through the surface of the base label and is partially broken by discharging the drug from the pocket part and electrically changed A storage unit for storing the time of electrical change in the circuit unit; a transmission unit for wirelessly transmitting the time information stored in the storage unit; and supplying power to the storage unit and the circuit unit A battery unit that includes a starting unit that receives an operation for starting the storage unit includes a, characterized by comprising a control unit which is joined to the ear portion of the base label.

  Thereby, the label according to the present invention is a label provided with a base label that is affixed to the blister package so that the control unit is disposed in a region corresponding to the ear of the blister package, and a circuit is formed on the surface. Since the unit has a function of storing and transmitting the electrical change time of the circuit, the control unit is arranged by effectively using the ear region of the blister package, and the medicine discharge time of the blister package is stored and transmitted. Etc. can be done. Therefore, it is possible to realize a label that appropriately manages the patient's medication history by simply attaching the blister package to the blister package without changing the existing blister package (or only with minor changes). Furthermore, since an activation unit for activating the storage unit is provided, management of system activation can be easily performed in a medical institution or a pharmacy.

  Moreover, the said memory | storage part, the said transmission part, the said battery part, and the said start part may be planarly arrange | positioned in parallel with the surface of the said base label in the said control part.

  According to this invention, since the storage unit, the transmission unit, the battery unit, and the activation unit are arranged in a plane, the sheet shape of the blister package is not changed, and the blister package in a state where the control unit is affixed. Transport and storage can be performed in the same way as when the control unit is not attached.

  The control unit may include a cover layer that protects the storage unit, the transmission unit, and the battery unit, and the cover layer may include a character display area.

  According to the present invention, the cover layer is provided on the control unit, and characters are displayed on the cover layer, so that the user can be alerted by characters at the ears of the blister package in the form of the protection of the control unit. .

  In addition, the storage unit stores at least the number indicating the year, month, day, hour, and minute when the circuit unit is electrically changed up to at least the same upper limit number of times as the number of medicines contained in the blister package. Also good.

  According to this invention, since the numbers indicating the year, month, day, hour, and minute at the time of medication of the patient are stored for at least the number of medicines contained in the blister package, the medication history information of the patient is appropriately stored. be able to.

  In addition, the storage unit, after the start unit has received a start operation, using the power of the battery unit, the energization means for passing a current to the circuit unit at a predetermined time interval, and the energization unit Change detection means for detecting a change in impedance value in the circuit unit.

  According to the present invention, since the change in the impedance value is detected by energizing the circuit unit at a predetermined time interval, for example, the battery power consumption can be saved or the battery capacity can be reduced as compared with the case where the energization is always performed.

  In addition, a cut portion which is a linear weak portion is formed so as to surround a discharge position of the medicine accommodated in each pocket portion in the base label, and the circuit portion is formed across the cut portion. It is good.

  According to the present invention, a linear fragile portion is formed so as to surround the discharge position of the medicine on the base label, and the circuit portion is straddled there, so that an unexpected position is broken when the medicine is discharged. The problem that the circuit does not break is suppressed, and the circuit is surely broken when the medicine is discharged.

  In addition, the wireless transmission by the transmission unit does not use the power stored in the battery unit, but generates an electromotive force generated in the control unit by electromagnetic induction by an electromagnetic wave transmitted from a device that receives information transmitted from the transmission unit. May be used for transmission.

  According to the present invention, when the medication history information is transmitted from the control unit, the power of the battery is not used for the power used for the transmission. Can be used. Therefore, the power consumption of the battery unit can be saved, or the capacity of the battery can be reduced.

  The control unit may include a reception unit that receives a radio signal, and the storage unit may store information received by the reception unit.

  According to this invention, it is possible not only to store the history of the medicine discharge time detected by the electrical change of the circuit unit, but also to store additional information from the outside for the label and the blister package. Therefore, for example, additional information related to medication can be stored in a label affixed to the blister package, thereby contributing to the realization of appropriate medication.

  Further, the information received by the receiving unit may include information on side effects and physical condition caused by taking the medicine.

  According to this invention, not only the history of drug discharge time detected by the electrical change of the circuit unit is stored, but also information on side effects and physical condition caused by taking the drug from the outside is transmitted to the label. It can be memorized. Therefore, it is possible to contribute to the realization of appropriate medication by storing information on side effects and physical condition caused by taking the medicine in the label attached to the blister package.

  Moreover, the label manufacturing method according to the present invention includes an adhesive layer, and is a non-conductive base label that is attached to the surface of the blister package in which a medicine contained in a pocket portion is discharged by the adhesive layer. On top, a base label is formed so that a current flows through the surface of the base label, and a circuit portion that is electrically broken and partly broken is formed by discharging the drug from the pocket portion. A base label manufacturing process, a storage unit that stores the time of electrical change in the circuit unit, a transmission unit that wirelessly transmits information stored in the storage unit, power to the storage unit and the circuit unit A control unit manufacturing process for manufacturing a control unit to be affixed to the base label, and a battery unit to be supplied; and an activation unit that accepts an operation to activate the storage unit; A sticking step of sticking the control part manufactured in the control part manufacturing process to the base label manufactured in the process so that the circuit part and the battery part are electrically connected to each other. Features.

  Thus, in the label manufacturing method of the present invention, first, a base label including a circuit unit and a control unit including a storage unit and a transmission unit for impedance value change time are manufactured, and then the control unit is provided on the base label. The label used for management of medication history can be manufactured by the step of applying. In particular, this manufacturing process has advantages such that the base label and the control unit are manufactured and stored in different locations, and that defective products in the electronic components of the control unit can be inspected before being attached to the base label.

  In addition, the program according to the present invention is a circuit unit that is formed such that a current flows through the surface of the blister package on which the drug is discharged and is partially broken and electrically changed by discharging the drug. And a blister package having a label attached thereto, the storage unit storing the time of electrical change in the circuit unit, and the transmission unit wirelessly transmitting the information stored in the storage unit and the ID information. A registration step of registering the ID information transmitted from the transmission unit in association with the patient, a reception step of receiving information on the time of electrical change transmitted from the transmission unit of the blister package, and a reception step thereof Storing the received time information as patient medication history information associated with the blister pack in the registration step; Characterized in that to execute the computer.

  Thereby, the program according to the present invention wirelessly receives the ID information of the sheet from the transmission unit of the blister package containing the medicine and stores it in association with the patient, and then discharges the medicine transmitted from the blister package. Since the time information is received and the received medicine discharge time is stored in association with the patient, a program for appropriately managing the patient's medication history is realized.

  In addition, the management system according to the present invention is a circuit that is formed so that a current flows through the surface of the blister package on which the drug is discharged, and is partially broken and electrically changed by discharging the drug. Unit, a storage unit that stores the time of electrical change in the circuit unit, and a transmission unit that wirelessly transmits information and ID information stored in the storage unit, and the label is affixed Registration means for registering the ID information transmitted from the transmission unit of the blister package in association with a patient, and reception means for receiving information on the time of electrical change transmitted from the transmission unit of the blister package; Storage means for storing the time information received by the receiving means as medication history information of a patient associated with the blister package by the registration means. To.

  Thus, the management system according to the present invention is affixed to the blister package, and includes a storage unit for information on medication time, a label provided with a transmission unit, a registration means for the transmitted blister package, and a transmitted medication time. Since the receiving means and the storage means are provided, the patient's medication history can be appropriately managed simply by attaching a label having a medication history management function to the blister package.

  In addition, the management method according to the present invention is a circuit that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged, and is partially broken and electrically changed by discharging the drug. A blister package having a label attached thereto, a storage unit that stores a time of electrical change in the circuit unit, and a transmission unit that wirelessly transmits information stored in the storage unit, Or a prescription step for prescribing to a patient at a pharmacy, a return step for returning the blister pack from which the drug has been discharged to the medical institution or pharmacy, and a blister pack returned by the return step. A reception step of receiving information on the time of electrical change transmitted from the transmission unit by the receiving device, and the information received in the reception step is described in association with the patient. A storing step of, characterized by comprising a.

  Thus, in the management method according to the present invention, the medicine contained in the blister package with the label provided with the storage unit and the transmission unit of the medication time is prescribed to the patient, and the patient uses the used blister package. And wirelessly receive and store the medication time from the returned blister pack. Therefore, the patient's medication history can be appropriately managed by a simple method in which a label having a medication history management function is attached to the blister package and the patient returns the used blister package.

  The program according to the present invention includes an input step for accepting input of information including side effects and physical condition caused by taking a medicine, a receiving part for receiving a radio signal, and a surface on the side where the medicine is discharged in a blister package. The circuit unit is configured such that a current flows through the circuit part, and a part of the circuit part is electrically broken to be electrically changed by discharging the medicine, and information on the time of the electrical change in the circuit part and the receiving unit are received. A storage unit for storing information, and causing the computer to execute a transmission step of wirelessly transmitting information including side effects and physical condition, which is received in the input step, toward a blister package having a label attached thereto. Features.

  As a result, the program according to the present invention accepts input of information including side effects and physical condition caused by taking the medicine, and stores information on the medicine discharge time in the blister package containing the medicine and information received wirelessly. Since information including side effects and physical condition is transmitted to the label having a storage unit, a program that appropriately manages not only the patient's medication history but also information including side effects and physical condition caused by taking the drug is realized. The

The figure which shows the label and PTP sheet of the Example of this invention. The figure which shows the example of a PTP sheet. The figure which shows the example of a base label. The top view which shows the example of a time logger. The side view which shows the example of a time logger. The figure which shows the example of an upper layer label. The figure which shows the structure of a label. The figure which shows a part of manufacturing process of a label. The flowchart which shows the manufacturing process of a PTP sheet with a time logger. The figure which shows the system structural example in a medical institution. The figure which shows the system structural example in a pharmacy. The figure which shows the process example at the time of the medicine prescription in a medical institution. The figure which shows the process example at the time of the medicine prescription in a pharmacy. The figure which shows the chemical | medical agent discharge | emission from a PTP sheet. The figure which shows the process example at the time of the PTP sheet return in a medical institution. The figure which shows discard of a PTP sheet. The flowchart which shows the example of the process sequence at the time of chemical | medical agent prescription. The flowchart which shows the example of the process sequence after prescription. The flowchart which shows the example of the process sequence at the time of PTP sheet return. The figure which shows the 2nd example of a circuit part. The figure which shows the 3rd example of a circuit part. The figure which shows the structural example of the system using a smart phone. The flowchart which shows the example of acquisition and a display process of medicine medication time. The flowchart which shows the example of transmission and the memory | storage process of information on a side effect or a physical condition. The figure which shows another structural example of the system using a smart phone. The flowchart which shows the example of the 1st process sequence under the structure of FIG. The flowchart which shows the example of the 2nd process sequence under the structure of FIG. The flowchart which shows the example of the 3rd process sequence under the structure of FIG. The flowchart which shows the example of the 4th process sequence under the structure of FIG. The figure which shows the 1st modification of the arrangement | positioning form of a time logger. The figure which shows another example of a time logger. The figure which shows another example of an internal structure of a time logger. The figure which shows the example which does not use an upper layer label. The figure which shows the arrangement | positioning procedure middle in the 2nd modification of the arrangement | positioning form of a time logger. The figure which shows the 2nd modification of the arrangement | positioning form of a time logger. The figure which shows the arrangement | positioning procedure middle in the 3rd modification of the arrangement | positioning form of a time logger. The figure which shows the 3rd modification of the arrangement | positioning form of a time logger. Sectional drawing of the 3rd modification of the arrangement | positioning form of a time logger.

  Embodiments of the present invention will be described below with reference to the drawings. First, FIG. 1 is a view showing a label 1 and a PTP sheet 2 (Press Through Pack Sheet, blister pack, blister pack) of an embodiment of the present invention. The label 1 is affixed to the back surface of the PTP sheet 2 (the surface on the side where the articles accommodated in the PTP sheet are discharged), and the PTP sheet 10 with time logger is created. The label 1 includes a base label 110 (lower layer label), a time logger 120, and an upper layer label 130.

  FIG. 2 shows the PTP sheet 2. The PTP sheet 2 illustrated in FIG. 2 has a substantially rectangular shape, and a plurality of pocket portions 201 (blister portions) are formed in a matrix in the vertical and horizontal directions. One drug 202 is accommodated in each pocket 201. The PTP sheet is made of, for example, a resin, for example, an aluminum sheet (on the back side of the pocket portion (the side from which medicine is discharged. Similarly, the upper surface in FIG. 1 is referred to as the back surface and the opposite surface is referred to as the front surface). (Aluminum foil) is affixed to close the pocket opening. When the user presses the pocket portion, the aluminum sheet is broken and the medicine is discharged.

  The PTP sheet 2 is provided with an ear portion 203 at the peripheral portion, which is a region where the pocket portion 201 is not formed, for example, when the user holds it by hand. In the PTP sheet 2 of the present invention, a part of the ears is widened as a region for time logger arrangement described later. In the example of FIG. 2, the length “a” of the upper ear portion 203 is made longer than the length “b” (for example, in the range of 20, 30, 35 mm to 40, 50, 60 mm).

  A base label 110 is shown in FIG. The base label 110 is made of an electrically insulating material such as synthetic paper, and is formed in the same shape as the PTP sheet (or the top and bottom and the left and right sides are about 2 mm smaller). The circuit portion 111 is formed (printed) with a conductive material (for example, silver ink, aluminum etching) so that electricity flows to the back side of the base label 110.

  A connection terminal 112 is formed in the circuit unit 111 for electrical connection with a time logger described later. In addition, in order to predetermine a breakage point of the base label when the medicine is discharged, a U-shaped cut 113 (half cut) formed as a linear fragile portion so as to surround the medicine passage position in each pocket portion of the base label. ) Is formed before circuit formation. As illustrated in FIG. 3, the circuit pattern is formed so as to straddle the U-shaped cut 113, and when the drug is discharged and the cut 113 is broken, a part of the circuit portion is also broken, and the entire resistance value (Broadly defined impedance value. In this specification, impedance includes impedance in an AC circuit in which a resistance component is a real part and a reactance component is an imaginary part and includes only a resistance component in a DC circuit. Furthermore, in a situation including both direct current and alternating current, the definition of general impedance (electrical impedance) as a ratio of voltage to current is not excluded.

  For example, the size of the circuit unit 111 is preferably 25 to 30 mm × 40 mm and the thickness is about 2 mm. An adhesive layer coated with an adhesive material is formed on the surface side of the base label 110 for application to the PTP sheet. Note that the shape of the cut 113 is not limited to the U-shape, and may be any shape that allows the drug to pass, such as an O-shape (connecting only one part) or a square shape.

  4 and 5 show a time logger 120 (electronic device, control unit). 4 is a plan view, and FIG. 5 is a side view as seen from the lower side of FIG. The time logger 120 includes an IC chip 123, a battery 124 (battery unit), an activation button 125 (switch unit) on the upper surface side of the base sheet 121, and a connection terminal 126 on the lower surface side, which are electrically connected. Has been.

  The IC chip 123 has a normal computer structure, and a CPU, a memory 123a (storage unit), a timer 123b, and the like are formed in the chip to detect and store the break time of the circuit unit 111. Execute (details will be described later). An antenna 123c (transmission unit) is also formed in the IC chip 123 to wirelessly transmit medication history information stored in the IC chip 123 (details will be described later). The memory 123a may be a volatile memory or a non-volatile memory (for example, EEPRPM or flash memory). The battery 124 supplies power for supplying current to the circuit unit 111 and for various processes in the IC chip 123. The start button 125 is a button for starting the time logger 120. The connection terminal 126 is provided for electrical connection with the connection terminal 112 of the circuit unit 111 described above. As described above, the time logger 120 is an electronic device that intensively realizes a time management (memory) function by adding a timer 123b, a battery 124, and the like to an existing IC tag including a memory 123a and an antenna 123c.

  As shown in FIG. 5, the time logger 120 having the above-described parts is protected by being covered with a cover layer label 127 from the upper side in the figure after a sheet 128 for protection and thickness adjustment is arranged. The The cover layer label 127 is printed with a character number such as a manufacturing number, an expiration date, an alert to the patient, and a code such as a barcode or a two-dimensional code (described later). The time logger 120 is affixed to the base label 110 by an adhesive layer 129 formed on the lower surface of the base sheet 121 in the figure. If the thickness of the time logger 120 indicated by c in FIG. 5 (in the direction orthogonal to the surface of the base label) is in the range of 2 mm to 3 mm (or 4, 5, 6 mm or less, for example), the time logger Since the attached PTP sheet 10 can be made thin, the transport and storage of the PTP sheet with the time logger 120 attached is the same as when the time logger 120 is not attached, without changing the sheet shape of the PTP sheet. It is suitable to be performed.

  FIG. 6 shows the upper label 130. The upper label 130 is formed with a half-cut 131 serving as a discharge passage for each medicine after the patient's precautions are printed. An adhesive layer for attaching to the base label 110 is formed on the surface side of the upper layer label 130.

  The above-mentioned members are integrated as shown in FIG. That is, the upper layer label 130 is attached to the back side of the base label 110 so as to protect the circuit unit 111. Then, the cover layer label 127 is attached to the time logger 120. As shown in FIG. 7, the cover layer label 127 is printed with a character number such as a serial number, expiration date, and alert to the patient, and a code 127a such as a barcode or a two-dimensional code.

  The character display for alerting the patient is, for example, “Please return without discarding” (the meaning of such display will be described later). The code 127a such as a bar code or a two-dimensional code relates to the traceability of the PTP sheet with time logger 10 or the drug 202 therein, such as a drug name, a manufacturing company name, a manufacturing place, a manufacturing date, a manufacturing number, and an expiration date. It is sufficient that information and the like are stored. The time logger 120 to which the cover layer label 127 is attached is attached to the base label 110. At that time, the connection terminal 126 of the time logger 120 and the connection terminal 112 of the base label 110 are electrically connected. As a result, a label 1 with a time logger is created. 7 and the like, the PTP sheet 2 and the base label 110 have a rectangular shape, and an ear is formed at the end in the long side direction. In the time logger 120, the IC chip 123, the battery 124, and the start button 125 are rectangular. Are arranged in a row in the short-side direction of the shape. Thereby, the control part of medication history management can be arranged using the space of the ear part effectively.

  Next, the manufacturing method of the label 1 and the PTP sheet 10 with a time logger will be described along the flowchart shown in FIG. In the manufacturing procedure of FIG. 9, first, the base label 110 is created in S10. This may be made of synthetic paper as described above. Next, the circuit part 111 is formed on the base label 110 in S20.

  The base label 110 on which the circuit unit 111 is thus formed is then wound around a winding roll in S30. An example of the winding roll 4 is shown in FIG. Since the base label 110 is made of flexible paper and has a small thickness by making the base label 110 with synthetic paper, it is wound around the roll 4 as shown in FIG. 8, stored, and transported to another place. Easy to do.

  Next, the time logger 120 is created in S40. As described above, the time logger 120 has the IC chip 123, the battery 124, and the activation button 125 disposed on one surface of the base sheet 121, and the connection terminal 126 disposed on the other surface. As the IC chip 123, the battery 124, the start button 125, and the connection terminal 126, for example, commercially available products may be used. Then, the sheet 128 and the cover layer label 127 are attached.

  The time logger 120 thus created is then affixed to the base label 110 in S50. Specifically, as shown in FIG. 8, the winding roll 4 may be rewound and the time logger 120 may be attached to the base label 110 sequentially. Thereby, the label 1 with a time logger is completed. In S60, if a label is attached to the PTP sheet, the PTP sheet 10 with time logger is completed. As described above, the manufacturing procedure of the label 1 with time logger and the PTP sheet 10 with time logger according to the present invention has an advantage that the manufacturing of the base label 110 and the manufacturing of the time logger 120 can be performed separately.

  Next, a medication history management system in the present invention will be described. 10 and 11 are configuration diagrams of a medication history management system in a medical institution and a pharmacy, respectively. The medication history management system in the present invention is established by combining these configurations with the PTP sheet 10 with time logger.

  10 and 11 includes a computer 301, a tag reader (tag reader / writer) 302, and a management program (a storage medium storing the program) 303. The computer 301 may be a commercially available personal computer, for example. The computer 301 includes a memory 304 (database) (see FIG. 15). The management program 303 is a computer program that governs overall processing related to medication management in the present invention, and is delivered to a medical institution or pharmacy in a state stored in a storage medium (for example, a CD-ROM). The management program 303 is a program that causes the computer 301 to (automatically) execute the processing portion of the computer in flowcharts such as FIGS. The management program 303 may be downloaded from the Internet.

  The tag reader 302 is equipped to acquire medication history information from the time logger 120. In the present invention, the tag reader 302 may use an existing non-contact IC tag reader (or IC tag reader / writer) using wireless communication in a frequency band of 13.56 MHz, for example.

  That is, the tag reader 302 has a transmission unit and a reception unit, transmits electromagnetic waves from the transmission unit, and if the time logger 120 is within the reach of the electromagnetic waves, an electromotive force is generated in the time logger 120 by electromagnetic induction. Occur. With this electromotive force, a signal including medication history information stored in the memory 123a is transmitted from the antenna 123c in response to a command from the IC chip 123. The tag reader 302 receives a signal transmitted from the antenna 123c by the receiving unit and acquires medication history information. At the time of drug prescription, the tag reader 302 receives the ID (stored in the memory 123a) of the time logger (or the PTP sheet to which the tag logger is attached) from the time logger 120 by the same method.

  The medication history management process is executed under the above system configuration. Below, the process sequence of the medication history management process using the PTP sheet with time logger 10 will be described. First, with reference to FIGS. 10 to 13, the medication history management processing procedure at the time of drug prescription shown in FIG. 17 will be described.

  In the medication history management processing procedure at the time of drug prescription, first, in S100, a computer 301, a tag reader 302, a management program 303 and the like are arranged in a medical institution or pharmacy as shown in FIGS. As described above, the computer 301 and the tag reader 302 may be existing ones. A management program 303 is installed in the computer 301 at a medical institution or pharmacy. The procedure of S100 may be performed in advance.

  Next, in S110, the drug is prescribed to the patient. It is assumed that the medicine 202 is accommodated in the PTP sheet with time logger 10 described above. The doctor or pharmacist performs the following processing before delivering the drug to the patient. First, in S <b> 120, a doctor, a pharmacist, or the like activates the time logger 120 by pressing the activation button 125 in the time logger 120. As a result, the information processing function of the time logger 120 is activated, for example, the timer 123b starts time calculation, and the CPU of the IC chip 123 starts the processing of FIG.

  Next, in S130, the doctor, the pharmacist, and the like read the ID of the time logger 120 (or the PTP sheet 10 with the time logger) by the tag reader 302 as shown in FIGS. The reading principle may be the same as that of a normal non-contact IC card reader as described above. The time logger 120ID is stored as a unique number or symbol for each time logger 120, for example, at the manufacturing stage of the time logger 120 or at the stage of attaching the time logger 120 to the PTP sheet 2. In subsequent S140, the computer 301 stores the time logger ID in association with the patient ID (predetermined). Next, in S150, the doctor or the pharmacist explains to the patient that the PTP sheet with time logger 10 is returned to the patient at the next visit (visit) without discarding the PTP sheet with time logger 10 even if it becomes empty. .

  The above processing is performed regardless of whether the medical prescription is performed at a medical institution or a pharmacy. When the medicine is prescribed at the pharmacy, the next S160 is executed. In S160, prescription information is transferred from the pharmacy computer 301 to the host computer 301 of the medical institution. Here, the prescription information includes, for example, the time logger ID of the PTP sheet 10 with the time logger of the prescribed medicine, the patient ID (or patient name) associated therewith, the prescription date and time (the time when the start button 125 is pressed or the time logger ID). The read time, specifically, for example, year (last two digits of the year), month, day, hour, minute). As indicated by arrows in FIG. 11, prior to drug prescription at the pharmacy, patient information such as a prescription number may be transmitted from the medical institution that issued the prescription to the pharmacy. The above is the processing procedure of FIG.

  In S120, when the start button 125 is pressed, the circuit unit 111 may be first energized to determine whether the impedance value is appropriate. Thereby, a defective product in which the circuit portion is broken can be detected. An appropriate initial impedance value may be stored in advance in the memory 123a, for example.

  Next, with reference to FIG. 14, the medication history management processing procedure after the drug prescription shown in FIG. 18 will be described. The processing procedure of FIG. 18 may be executed automatically by, for example, programming in advance and storing it in the memory 123a, calling it by the IC chip 123, and so on.

  In the medication history management processing procedure after drug prescription, first, in S200, it is determined whether a predetermined time has elapsed since the previous detection. Here, the previous detection refers to the previous energization of the circuit unit in S210. The elapsed time is calculated by the timer 123b. The predetermined time may be, for example, 5 minutes, 10 minutes, 15 minutes, 20 minutes, 30 minutes, or the like. If the predetermined time has elapsed (S200: YES), the process proceeds to S210. If the predetermined time has not yet elapsed (S200: NO), S200 is repeated to wait for the predetermined time.

  In step S210, the circuit unit 111 is energized. Accordingly, a current flows through the circuit unit 111 with the power supplied from the battery 124.

  Subsequently, in S220, it is determined whether or not the impedance value of the circuit unit 111 has increased from the previous time. As described above, the circuit part 111 is formed so as to straddle the U-shaped cut 113 in the base label 110, the medicine is discharged (see FIG. 14), and when the cut 113 in the corresponding pocket part 201 is broken, The part of the circuit unit 111 is also broken, and the impedance value of the circuit unit 111 increases.

  Therefore, when the patient discharges the medicine between the previous detection and the current detection, the impedance value at the current detection increases from the impedance value at the previous detection. In S220, such an increase in impedance is detected. If an increase in impedance value is detected (S220: YES), the process proceeds to S230. If an increase in impedance value is not detected (S220: NO), the process returns to S200 and the above process is repeated. The increase in the impedance value may be detected by, for example, incorporating a current value sensor in the IC chip 123 and decreasing the current value.

  After proceeding to S230, the current time calculated by the timer 123b is stored in the memory 123a. More specifically, the current time is, for example, a 10-digit number of year (last two digits of the year), month, day, time (24-hour display), and minute. The current time in S230 is a medication time in an approximate sense. Therefore, every time an increase in the impedance value is detected in S230, the memory 123a is sequentially written with new times in another place, and a medication time history is formed. The memory 123a is provided with a storage capacity capable of storing such 10-digit numbers for the number of pockets of the PTP sheet 2 or, for example, at least 50 times. The battery has a capacity that allows the above processing to be performed, for example, for at least 1.5 months to 2 months.

  In the process of S230, it is necessary to consider the case of taking a plurality of medicines at a time. Accordingly, in S230, the IC chip calculates how many tablets have been taken (how many pockets have been broken) from the detected increase in the impedance value, and the timer 123b calculates the same number as the number of tablets taken. The current time is stored in the memory 123a. Or you may change so that not only the present time (medication time in an approximate meaning) but the number of medication tablets may be memorize | stored in S230.

  In S230, a value corresponding to the current time may be used instead of the current time itself. The current time equivalent value includes, for example, an elapsed time since the activation button 125 is turned on, or an integrated value of the number of energization executions in S210 after the activation button 125 is turned on. In this case, the time adjustment of the timer 123b is unnecessary. In short, the storage unit is provided with equivalent value storage means for storing the equivalent value corresponding to the time when the impedance value in the circuit unit corresponds to the time, at least up to the storage upper limit number of times stored in the PTP sheet. When storing the current time itself in the memory 123a, for example, when reading the time logger in S130, the numerical information of the current time held by the computer 301 is transmitted from the tag reader 302, and the time logger 120 receives the numerical information and receives the memory 123a. And the IC chip 123 calculates the current time using this and the timer 123b.

  Next, in S240, the impedance value at that time is stored. This can be stored by overwriting the memory 123a sequentially. The impedance value stored in S240 is used as the previous impedance value in S220.

  Next, in S250, it is determined whether or not all the medicines have been discharged from the PTP sheet 2. Specifically, this determination may be made by determining whether or not the current impedance value has reached the impedance value after all the drugs are discharged. When it is determined that all the medicines have been discharged (S250: YES), the processing of FIG. 18 is terminated, and when it is determined that all the medicines have not yet been discharged (S250: NO), the process returns to S200 and the above Repeat the procedure. The above is the processing procedure of FIG. Note that the process of S250 may be omitted and the process of FIG. 18 may be executed until the battery runs out.

  Next, with reference to FIG. 15 and FIG. 16, the medication history management processing procedure after the PTP sheet return shown in FIG. 19 will be described. In the medication history management processing procedure after the PTP sheet is returned, first, in S300, the patient is alerted to the character display to return on the cover layer label 127, and the next visit to the medical institution (or pharmacy) Bring the PTP sheet 10 with the time logger from which the medicine has been discharged, and return it.

  Next, in S310, the medication history is read from the returned PTP sheet with time logger 10 at the medical institution or pharmacy. In the reading method, as described above, when an electromagnetic wave is transmitted from the transmission unit of the tag reader 302 and the time logger 120 is within the reachable range of the electromagnetic wave, an electromotive force is generated in the time logger 120 by electromagnetic induction. By this electromotive force, a signal including medication history information stored in the memory 123a of the IC chip 123 is transmitted from the antenna 123c. The tag reader 302 receives a signal transmitted from the antenna 123c by the receiving unit and acquires medication history information.

  When the individual medication time itself is stored in the memory 123a, the computer 301 receives the medication time history itself. Further, when the medication time equivalent value (the above-mentioned current time equivalent value) is stored in the memory 123a, the computer 301 determines each individual value from the received equivalent value and the stored ON time of the activation button. The history of medication time itself is calculated. In short, there is provided time calculation means for calculating a history of medication time from the equivalent value stored by the equivalent value storage means.

  In step S310, the computer 301 stores the received (or calculated) medication history in the database 304 in association with the patient ID. When the PTP sheet with time logger 10 is returned to the pharmacy, information may be transmitted from the pharmacy to the medical institution and stored in the database 304 of the medical institution. Then, the IC chip 123 erases the storage in the memory 123a in subsequent S320. Next, in S330, the medical institution or pharmacy discards the PTP sheet. In this disposal processing, for example, the battery 124 may be separated into the battery 124 and the others according to the disposal rules for the battery in the relevant local government, and each may be discarded as a waste battery and a waste plastic. For this purpose, a perforation may be formed around the battery 124 in the time logger 120 so that the battery 124 can be easily cut off. The above is the processing procedure of FIG.

  The above-described embodiments can be modified as appropriate without departing from the scope of the claims. For example, the patient returns the PTP sheet 10 with the time logger in the above, but only the time logger 120 may be separated and returned. For this purpose, for example, a half cut (perforation) may be formed in the illustrated horizontal direction at a position below the time logger 120 in the base label 110 in FIG. In short, it is only necessary that a cut portion for separating the control portion from the PTP sheet is provided.

  Further, the pattern of the circuit portion 111 formed on the base label 110 is not limited to FIG. In the example of FIG. 3, a circuit pattern parallel to the cuts 113 arranged in one vertical column is formed. However, as shown in FIG. 20, an independent circuit is provided for each cut 113. It may be formed. In this case, the detection of the change (increase) in the impedance value in S220 is changed to detection of whether or not the number of circuits having a current value of zero has increased among all the numbers of circuits.

  The pattern of the circuit unit 111 may be formed as shown in FIG. In the base label 110 ″ of FIG. 21, there are two connection terminals 112, and a circuit portion 111 is formed in which circuits formed so as to straddle all the cut portions 113 are connected in parallel. Then, the number of connection terminals 112 is small (the minimum number), and it is only necessary to detect a change in one impedance value (for example, in the example of FIG. 3, a change in two impedance values is detected). It is not limited to the examples of FIGS. 20 and 21, and any pattern may be used as long as the circuit unit 111 is formed so that the discharge of the medicine is detected as a change in impedance value (electrical change in the circuit unit 111).

  Further, the present invention provides the above-described embodiment so that additional information can be written on the PTP sheet with time logger 10 using an information communication terminal such as a smartphone (a portable information communication terminal in which an information processing function other than a telephone is added to a mobile phone). May be changed. A specific system configuration example in such an embodiment is shown in FIG. The system of FIG. 22 includes a smartphone 400 and a server 500 in addition to the PTP sheet with time logger 10.

  The smartphone 400 includes a CPU 401, a RAM 402, a ROM 403, a display / touch panel 404, and a communication unit 405 as configurations related to the present invention. The CPU 401 manages various types of information processing, and the RAM 402 is a volatile memory and constitutes a work area of the CPU 401. The ROM 403 is a non-volatile memory that stores various types of information. The display / touch panel 404 displays various types of information and accepts input by contact from the user. The communication unit 405 communicates and communicates with other communication devices and mobile phones wirelessly via a telephone line network or a communication network.

  A program 406 and tag reader / writer software 407 are stored in the ROM 403 of the smartphone 400. The program 406 is a program that causes the smartphone 400 to execute functions necessary for the present invention. Specifically, the program 406 is a program for executing the processes shown in FIGS. 23 and 24 (the process automatically executed by the CPU 401).

  The tag reader / writer software 407 is software for causing the smartphone 400 to execute the tag reader / writer function. When the tag reader / writer software 407 is activated, for example, electromagnetic waves are output from the communication unit 405 to the periphery. When the tag (time logger 120) exists within the electromagnetic wave reachable range, the tag (time logger 120) can transmit and receive radio waves with the power supplied by the electromagnetic wave, and the tag (time logger 120) from the smartphone 400 side. It is possible to read and write information.

  The server 500 (server device) has the same equipment and functions as a normal computer, and is arranged for downloading the program 406 for the present invention to the smartphone 400. Specifically, when accessing the server 500 from the smartphone 400 and instructing the download of the program 406, the program 406 stored in the memory 501 of the server 500 is stored in the ROM 403 of the smartphone 400 via the communication network.

  Based on the above configuration, the use of the smartphone 400 is added to the above-described medication history management system to further enhance information processing related to medication. The specific processing procedure is shown in FIG. 23 and FIG. FIG. 23 shows a procedure for reading the medication time and the like from the PTP sheet with time logger 10 on the smartphone 400 side. FIG. 24 shows a procedure for writing information on side effects, physical condition, and the like on the PTP sheet with time logger 10 from the smartphone 400 side. Note that the processing in FIGS. 23 and 24 may be performed by the patient during a predetermined medication period, for example. Of the processes in FIGS. 23 and 24, the CPU 401 may automatically execute processes other than those performed by the user.

  In the processing procedure of FIG. 23, first, in step S400, the user (patient) activates the tag reader / writer software 407 on the smartphone 400. Thereby, as described above, when an electromagnetic wave is output from the smartphone 400 to the periphery and the PTP sheet 10 with a time logger exists within the electromagnetic wave reachable range, wireless signals can be transmitted and received by the PTP sheet 10 with a time logger. As a result, the PTP sheet with time logger 10 wirelessly transmits the history of the medicine ID and the medication time up to that point (or the dosage may be included) stored in the memory 123a in step S430.

  In step S410, the smartphone 400 receives the history of the medicine ID transmitted from the time logger-attached PTP sheet 10 and the medication time up to that point (or the dosage may be included). In step S <b> 420, the smartphone 400 displays the received medicine ID and the history of the medication time up to that point (or may include the dosage) on the display / touch panel 404. By the above processing, the patient can know the history of medication time up to the present time by himself. For example, the patient properly taking a predetermined amount at a predetermined time, or forgetting to take a medicine. Can recognize themselves. Therefore, it contributes to appropriate medication habits.

  In the process of FIG. 24, first, in step S500, the user (patient) starts the tag reader / writer software 407 on the smartphone 400 by the user (patient). Thereby, as described above, when an electromagnetic wave is output from the smartphone 400 to the periphery and the PTP sheet 10 with a time logger exists within the electromagnetic wave reachable range, wireless signals can be transmitted and received by the PTP sheet 10 with a time logger.

  Subsequently, in S510, the user inputs the side effects caused by taking the medicine and the current physical condition on the display / touch panel 404. This input may be, for example, character (or symbol) input, or may be a method in which options prepared by the program 406 are displayed on the display / touch panel 404 and the user selects them. What is necessary is just to memorize | store the input content (temporarily) with the information (acquired by the timer 123b) of the input date. The input of S510 may not be the timing shown in FIG. 24, but may be a form in which the input at another time point is stored.

  Then, the smartphone 400 wirelessly transmits the information regarding the side effects and physical condition and the input date / time information (side effect / physical memo) input and stored in S520. The PTP sheet with time logger 10 receives the transmitted information in S530. In subsequent S540, the PTP sheet with time logger 10 stores the received side effect / physical condition (date and time) memo in the memory 123a.

  Through the above processing, not only information on the medication history but also information on side effects and physical condition are stored in the memory 123a of the PTP sheet with time logger 10. This information may be read by the medical institution in S310. Thereby, since the detailed information regarding a side effect and a physical condition can be acquired on the side of a doctor, more appropriate medication can be realized using this information.

  Next, FIG. 25 to FIG. 29 show an example in which a smartphone is further utilized. In this embodiment, a medication history is transmitted to a medical institution using a smartphone, or information on the regular time of medication is transmitted from the medical institution to the smartphone. , Etc. are executed.

  A system configuration example of FIG. 25 will be described. Although the internal configuration of the smartphone 400 is substantially the same as that in FIG. 22 (the same elements are denoted by the same reference numerals and redundant description is omitted), the short-range wireless communication unit 408 is provided in FIG. The short-range wireless communication unit 150 is also provided in the time logger 120 (PTP sheet 10 with time logger).

  Short-range wireless communication (for example, Bluetooth (registered trademark), wi-fi (registered trademark)) is executed between the short-range wireless communication unit 408 and the short-range wireless communication unit 150, and information is transmitted and received. The ROM 403 of the smartphone 400 stores application software 409 (software) in which the processing procedure of this embodiment is programmed. The software 409 may be downloaded in the same manner as the method using FIG.

  As described above, the medical institution computer 301 includes the database 360 for mainly storing information such as patient medication information. The computer 301 includes a CPU 305 that manages information processing, a volatile storage unit as a work area of the CPU, and a non-volatile storage unit that stores programs and data necessary for CPU information processing (not shown). ). The computer 301 includes an arbitrary input unit 306 that receives input from the user, such as a keyboard and a mouse.

  An example of the processing procedure of the system under the configuration example of FIG. 25 is shown in FIGS. The processing procedure shown in FIG. 26 is a processing procedure in which the medication time detected by the time logger is transmitted to a smartphone and further to a medical institution. In FIG. 26, the processing of the time logger 120, the processing of the smartphone 400, and the processing at the medical institution are shown from the left side. Except for the processes performed by the user in the processes of FIG. 26, the time logger 120, the CPU 401, and the CPU 305 may perform the processes automatically.

  In the processing procedure of FIG. 26, first, in S600, the user activates application software 409 (an application) according to the present example, which is stored in the smartphone 400 that is powered on. The application 409 executes S640 and S650 described later. The application 409 may be automatically activated when the smartphone 400 is turned on (the same applies to the following FIG. 27 and subsequent figures).

  In S610 and S620, when the time logger 120 and the smartphone 400 are within the predetermined short-range wireless communication range, a short-range wireless communication connection is automatically established as is well known. Next, in step S630, the time logger 120 transmits information such as the medicine ID and the medication time (history) stored in its own memory 123a by the short-range wireless communication unit 150.

  In step S640, the CPU 401 of the smartphone 400 receives the medicine ID and the medication time (history) transmitted in step S630 through the short-range wireless communication unit 408. Subsequently, the CPU 401 of the smartphone 400 transmits the received medicine ID and medication time (history thereof) to the computer 301 of the medical institution. This transmission may be performed via the public line network (mobile phone network) using the communication unit 405.

  The medical institution computer 301 receives this in S660, and stores the medication time (history) in a manner corresponding to the corresponding drug ID in the database 304 provided in S670. The above is the processing procedure of FIG. Through the above procedure, information on the medication time is automatically transmitted from the time logger to the medical institution via the smartphone. Therefore, in this embodiment, the process of returning the used PTP sheet with time logger to the medical institution may be omitted.

  Next, FIG. 27 shows a processing procedure for transmitting side effects, physical condition, etc. of a patient to a medical institution using a smartphone. In the process of FIG. 27, first, in S700, the user (patient) activates the application 409 according to the present invention on the smartphone 400 that is powered on. The application 409 executes S720 described later.

  In step S <b> 710, the user inputs side effects, physical condition notes, and the like using the display / touch panel 404. Note that this input can improve user convenience if, for example, an option prepared in advance is displayed on the display 404 and is selected from the displayed options. In S720, the CPU 401 of the smartphone 400 transmits the side effect, physical condition memo, and the like input in S710 using the communication unit 405 together with the current date and time (and the medicine ID prescribed to the patient).

  In S730, the computer 301 of the medical institution receives the transmitted side effect, physical condition memo, etc. via the mobile phone network (public line network). In step S740, the CPU 305 of the computer 301 stores the received side effect, physical condition memo, and the like in the database 304 in association with the medicine ID. The above is the processing procedure of FIG. By this procedure, the patient can transmit information such as side effects and physical condition to the medical institution in a simple procedure using the smartphone 400, and the medical institution can automatically organize and store the information.

  Next, FIG. 28 shows a processing procedure for transmitting information on regular medication time from a medical institution to a patient's smartphone. In the procedure of FIG. 28, first, in S800, a doctor (a nurse, a pharmacist, or other medical personnel) inputs a regular administration time of a medicine prescribed for the patient.

  On the other hand, in step S810, the user (patient) activates the application 409 related to the present embodiment on the smartphone 400 that is powered on. The application 409 executes S830, S850, and S860, which will be described later. In S830, the user transmits a request signal requesting transmission of the regular medication time. Note that the process of S830 may be automatically executed by the application 409.

  The computer 301 of the medical institution receives the request signal in S820. Upon receiving the request signal, the CPU 305 of the computer 301 transmits the regular medication time in S840.

  In S850, the smartphone 400 receives the regular medication time transmitted in S840. In step S860, the CPU 401 of the smartphone 400 stores the received regular medication time in its storage unit, for example, the ROM 403. The above is the processing of FIG. With this processing procedure, the user can easily (automatically) obtain information on the regular time of medication. Information other than the regular medication time (for example, precautions regarding medication) may be transmitted together so that the user can receive it and display it on the smartphone 400 for confirmation.

  In the present invention, using the information on the regular medication time stored in the smartphone 400 by the processing of FIG. 28, an alarm can be issued from the smartphone to the patient when the regular medication time has not passed and the medication has not been dispensed. FIG. 29 shows an example of the processing procedure.

  In the process of FIG. 29, first, in step S900, the user (patient) activates the application 409 related to the present embodiment on the smartphone 400 that is powered on. The application 409 executes S930 and S950 to S970 described later. In S910 and S920, when the time logger 120 and the smartphone 400 are within the predetermined short-range wireless communication range, the short-range wireless communication is automatically connected.

  Subsequently, in S940, the time logger 120 transmits the medicine ID and the medication time (history thereof) by short-range wireless communication in the same manner as in S630 described above. The smartphone 400 receives the transmitted medicine ID and medication time (history thereof) in S930.

  In step S950, the CPU 401 of the smartphone 400 determines whether or not the regular medication time has passed. If the regular medication time has passed (S950: YES), the process proceeds to S960, and if the regular medication time has not passed (S950: NO), the processing in FIG. 29 ends.

  After proceeding to S960, the CPU 401 determines whether or not the medicine has been dispensed by the current time. If already administered (S960: YES), the process of FIG. 29 is terminated, and if not yet administered (S960: NO), the process proceeds to S970.

  After proceeding to S970, the CPU 401 outputs an alarm prompting the patient to take medication by voice or video (character display), for example, using the voice output unit provided in the smartphone 400 or the display 404 (or both). Of the processes of the smartphone 400, the processes from S930 to S960 may be repeatedly executed at predetermined intervals, for example.

  The above is the processing procedure of FIG. 28 and 29, the information on the regular medication time is automatically transmitted from the medical institution to the patient's smartphone, and the smartphone automatically obtains the medication time from the time logger and is dispensed at the regular time. If there is no alarm, an alarm is issued. Therefore, it is possible to prompt medication at regular time by automatic processing. Therefore, it can contribute to the establishment of appropriate medication habits.

  In the above, the time logger 120 is joined to the front surface side (or back surface side) of the ear portion 203 of the blister pack, but the present invention is not limited to such a form. In the example shown in FIG. 30, the time logger 120 is joined to the tip side of the ear portion 203 of the blister pack. In this example, there is an advantage that the size of the time logger 120 is not restricted by the size of the ear portion 203. Note that the thickness may be emphasized in the drawings including those in FIG. 30 for clarity.

  Further, the activation button 125 in the above embodiment is not limited to the example of FIG. 31 and 32 show another embodiment. In this example, instead of the activation button 125, an insulation sheet made of an insulator is provided for the activation operation of the time logger 120.

  Specifically, in FIGS. 31 and 32, as a main internal structure of the time logger 120, an IC chip 123 and a battery 124 are arranged on a substrate 142. It suffices that the short-range wireless communication unit 150 described above is formed in the IC chip 123. The battery 124 is accommodated in a battery recess 124a formed on the substrate 142, and an insulating sheet 124c is sandwiched between the battery 124 and the electrode 124b at the time of shipment.

  The substrate 142, the IC chip 123, and the battery 124 are accommodated between the upper cover 140 and the lower cover 141. For example, an engaging portion (not shown) is formed in each of the upper cover 140 and the lower cover 141, and the covers 140 and 141 are closed as shown in FIG. A time logger 120 is arranged on the side.

  At that time, the leading end portion of the insulating sheet 124 c is taken out from the hole portion 143 formed in the cover 140. When the user grasps and pulls out the leading end portion of the insulating sheet 124c, the battery 124 and the electrode 124b are electrically connected to start the time logger 120. Thereby, the structure for starting the time logger 120 is simplified using an insulating sheet.

  Further, the above-described upper layer label 130 may not be provided. FIG. 33 shows an example of such a form. In this embodiment, a circuit portion 162 made of a conductor from the time logger 120 and a cut portion 161 having a shape along the outer edge of the medicine discharge port are formed on the surface of the base label 160.

  In the example of FIG. 33, the cut portion 162 is formed in two semicircular shapes along the outer edge of the medicine discharge port, and the circuit portion 162 is formed through a position where the cut portion 161 is not formed in the discharge port. ing. Thereby, the circuit part 162 is reliably broken by the discharge of the medicine. By sticking such a base label 160 to the surface of the PTP sheet 2 on the drug discharge side, a PTP sheet with a time logger is created.

  Examples of the mode in which the time logger 120 is joined to the ear part 203 include the following. In the example of FIGS. 34 and 35, the time logger 120 is folded back to the blister side and joined to the ear 203. In the arrangement procedure, first, as shown in FIG. 34, a label with a time logger is attached to the surface of the PTP sheet 2 on the medicine discharge side. At that time, the time logger 120 is set to a position protruding from the ear portion 203. Then, as shown in FIG. 35, the portion of the time logger 120 is folded back 180 degrees so that one surface (main surface) of the time logger 120 is in surface contact with the blister side of the ear portion 203. In this state, the time logger 120 is joined (attached) to the ear portion 203. In the case of this arrangement form, the medicine discharge side in the PTP sheet can be made flat.

  In the example of FIGS. 36 to 38, the time logger 120 is accommodated in the recess formed in the ear 203. Specifically, as shown in FIG. 36, a bulging portion 230b bulging in the same direction as the blister is formed in the ear portion 203 of the PTP sheet. The size and shape of the bulging portion 230b may be any size and shape suitable for accommodating the time logger 120 without a gap (or with a minute gap).

  Then, as shown in FIG. 37, the time logger 120 is accommodated in the bulging portion 230b. At this time, as shown in the cross-sectional view of FIG. 38, all of the time logger 120 may be accommodated in the recess formed by the bulging portion 230b through the opening 230a. In this state, the time logger 120 is attached to, for example, the bulging portion 230b to stabilize the fixation. 36 to 38 also has an advantage that the medicine discharge side of the PTP sheet can be made flat. 34 to 38, the insulating sheet 124c may be disposed at an appropriate position so that the user can extract it and start the time logger 120.

  In the above description, the smartphone 400 is used. However, the present invention is not limited to this, and any wireless communication device including a mobile phone, a computer with a wireless communication function, or the like may be used. In addition, the medical institution may be a pharmacy or the like.

1 Label 2 PTP sheet (blister package)
10 PTP sheet with time logger 110 Base label 120 Time logger (control unit)

Claims (18)

A label that is affixed to a blister package having a plurality of pocket portions that are aligned vertically and horizontally so as to contain a medicine, and ear portions that are peripheral regions where the pocket portions are not formed. And
An adhesive layer, and a base label having no electrical conductivity, attached to the surface of the blister package in which the medicine accommodated in the pocket is discharged by the adhesive layer;
A circuit part that is formed so that an electric current flows on the surface of the base label, and a part of the circuit part is broken and electrically changed by discharging the medicine from the pocket part,
A storage unit that stores the time of electrical change in the circuit unit, a transmission unit that wirelessly transmits the time information stored in the storage unit, and a battery unit that supplies power to the storage unit and the circuit unit And an activation unit that accepts an operation for activating the storage unit, and a control unit joined to the ear part in the base label,
A label characterized by comprising.   The label according to claim 1, wherein the storage unit, the transmission unit, the battery unit, and the activation unit are arranged in a plane in parallel with the surface of the base label in the control unit.   The label according to claim 1, wherein the control unit includes a cover layer that protects the storage unit, the transmission unit, and the battery unit, and the cover layer has a display area for characters or codes.   The said memory | storage part memorize | stores the number which shows at least year, month, day, hour, and minute when the said circuit part changed electrically at least to the same memory upper limit number of times as the number of the medicines accommodated in the said blister package. The label according to any one of 1 to 3. The storage unit
Energization means for causing a current to flow through the circuit unit at predetermined time intervals using the power of the battery unit after the startup unit has received a startup operation;
The label according to any one of claims 1 to 4, further comprising: a change detecting unit that detects a change in impedance value in the circuit unit that is energized by the energizing unit. A cut portion which is a linear fragile portion formed so as to surround the discharge position of the medicine accommodated in each pocket portion in the base label,
The label according to any one of claims 1 to 5, wherein the circuit portion is formed across the cut portion.   The wireless transmission by the transmission unit does not use the power stored in the battery unit, but generates an electromotive force generated in the control unit by electromagnetic induction generated by an electromagnetic wave transmitted from a device that receives information transmitted from the transmission unit. The label according to any one of claims 1 to 6, which is used for transmission.   The label according to claim 1, wherein the control unit includes a reception unit that receives a radio signal, and the storage unit stores information received by the reception unit.   The label according to claim 8, wherein the information received by the receiving unit includes information on a side effect or physical condition caused by taking a medicine. An electric current is applied to the surface of the base label on the surface of the base label that is provided with an adhesive layer and is attached to the surface of the blister package in which the medicine contained in the pocket is discharged by the adhesive layer. A base label manufacturing process for manufacturing a base label that is formed to flow and in which a circuit portion that is partially broken and electrically changed by discharging the medicine from the pocket portion is formed;
A storage unit that stores the time of electrical change in the circuit unit, a transmission unit that wirelessly transmits information stored in the storage unit, a battery unit that supplies power to the storage unit and the circuit unit, and the storage A control unit manufacturing process for manufacturing a control unit to be affixed to the base label,
A pasting step of pasting the control unit manufactured in the control unit manufacturing step on the base label manufactured in the base label manufacturing step so that the circuit unit and the battery unit are electrically connected;
A method for producing a label, comprising: A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. ID information transmitted from the transmission unit in a blister package to which a label comprising a storage unit that stores a change time and a transmission unit that wirelessly transmits information and ID information stored in the storage unit is attached. A registration step of registering in association with the patient;
A receiving step of receiving information on the time of electrical change transmitted from the transmission unit of the blister package;
Storing the time information received in the receiving step as patient medication history information associated with the blister package in the registration step;
A program that causes a computer to execute. A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. A label that includes a storage unit that stores a time of a change, and a transmission unit that wirelessly transmits information and ID information stored in the storage unit,
Registration means for registering ID information transmitted from the transmission unit of the blister package to which the label is attached in association with a patient;
Receiving means for receiving information on the time of electrical change transmitted from the transmission unit of the blister package;
Storage means for storing the time information received by the receiving means as medication history information of a patient associated with the blister package by the registration means;
A management system characterized by comprising: A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. A prescription step of prescribing a blister package with a label attached thereto to a patient at a medical institution or pharmacy, the storage unit storing a time of change, and a transmission unit wirelessly transmitting information stored in the storage unit; ,
A return step in which the patient returns the blister package from which the medicine has been discharged to the medical institution or pharmacy;
A reception step of receiving information on the time of electrical change transmitted from the transmission unit of the blister package returned in the return step by a receiving device;
A storage step of storing the information received in the receiving step in association with the patient;
A management method characterized by comprising: An input step for accepting input of information including side effects and physical condition caused by taking the medicine;
A receiving unit that receives a radio signal and a blister package that is formed so that a current flows through a surface of the blister package on the side where the drug is discharged. Received in the input step toward a blister package having a label provided with a circuit unit and a storage unit for storing information on time of electrical change in the circuit unit and information received by the receiving unit A transmission step of wirelessly transmitting information including side effects and physical condition;
A program that causes a computer to execute. A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. A prescription step of prescribing a blister package with a label attached thereto to a patient at a medical institution or pharmacy, the storage unit storing a time of change, and a transmission unit wirelessly transmitting information stored in the storage unit; ,
A first transmission step of transmitting information on the electrical change time from the transmission unit of the blister package prescribed in the prescription step to a wireless communication terminal possessed by a patient;
A second transmission step of transmitting the electrical change time information transmitted in the first transmission step from the wireless communication terminal possessed by the patient to a communication terminal provided in a medical institution or pharmacy;
A management method characterized by comprising: A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. The electrical change time transmitted from the transmission unit of the blister package to which a label comprising a storage unit that stores the change time and a transmission unit that wirelessly transmits information stored in the storage unit is attached. A receiving step for receiving the information of
A transmission step of transmitting information on the time of the electrical change received in the reception step to a communication terminal provided in a medical institution or pharmacy;
A program that causes a computer to execute. A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. A prescription step of prescribing a blister package with a label attached thereto to a patient at a medical institution or pharmacy, the storage unit storing a time of change, and a transmission unit wirelessly transmitting information stored in the storage unit; ,
A first transmission step of transmitting information on the electrical change time from the transmission unit of the blister package prescribed in the prescription step to a wireless communication terminal possessed by a patient;
A second transmission step of transmitting information on regular medication time from a medical institution or a pharmacy to a wireless communication terminal possessed by the patient;
When the regular medication time transmitted by the second transmission step has passed and the electrical change is not indicated in the information transmitted by the first transmission step, an alarm is issued by the wireless communication terminal possessed by the patient. An alarm step to emit;
A management method characterized by comprising: A circuit part that is formed so that an electric current flows through the surface of the blister package on which the drug is discharged and is partially broken by discharging the drug, and an electrical circuit in the circuit part. The electrical change time transmitted from the transmission unit of the blister package to which a label comprising a storage unit that stores the change time and a transmission unit that wirelessly transmits information stored in the storage unit is attached. A first receiving step of receiving the information of:
A second receiving step of receiving information on a regular medication time transmitted from a medical institution or pharmacy;
An alarm is issued from a predetermined alarm means when the normal medication time transmitted by the second reception step has passed and the electrical change is not indicated in the information transmitted by the first reception step. An alarm step to control;
A program that causes a computer to execute.

Images