JP6405380B2 - 脂肪吸引した脂肪をアリコートに分割するシステムおよび方法 - Google Patents
脂肪吸引した脂肪をアリコートに分割するシステムおよび方法 Download PDFInfo
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- JP6405380B2 JP6405380B2 JP2016530665A JP2016530665A JP6405380B2 JP 6405380 B2 JP6405380 B2 JP 6405380B2 JP 2016530665 A JP2016530665 A JP 2016530665A JP 2016530665 A JP2016530665 A JP 2016530665A JP 6405380 B2 JP6405380 B2 JP 6405380B2
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- syringe
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/04—Seals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3695—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with sedimentation by gravity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/08—Lipoids
Description
脂肪吸引によって取り出された脂肪物質を真空状態で保存した密閉容器を準備し、
当該容器を穿孔して一定分量の脂肪物質を採取し、汚染物質から隔離して保存し、
上記分量の採取した脂肪物質を構成する水様液体から脂肪を分離して、少なくとも1つの脂肪アリコートを作り、
上記アリコートを、浸潤処置で使用するまで、汚染物質から隔離して、利用可能な状態で保存する。
Claims (10)
- 脂肪吸引によって得られた一定量の脂肪物質を容器から採取し、該採取した量を密閉保存する採取手段(2、3)を含む、脂肪吸引した脂肪をアリコートに分割するシステムにおいて、該システムはさらに、
前記採取手段(2、3)に連通可能であって前記の量の少なくとも一部を収容でき、前記脂肪物質を構成する水様液体から重力によって脂肪を分離させるために、プランジャを上に、嘴部を下に向けて配置された少なくとも1つの分離注射器(4)と、
該採取手段(2、3)を前記分離注射器(4)に密閉連通させる第1の連結手段(5)と、
前記分離注射器(4)に連通させ、該分離注射器(4)から排出された前記水様液体を収容できる少なくとも1つの廃棄用容器(6)と、
前記分離注射器(4)に密閉連通させ、該分離注射器(4)から排出された脂肪アリコートを収容でき、脂肪を密閉保存し、浸潤させるために注入できる少なくとも1つの注射装置(7、8)と、
前記分離注射器(4)と前記廃棄用容器(6)、または該分離注射器(4)と前記注射装置(7、8)とを交互に密閉連通できる第2の連結手段(9)とを含み、
該注射装置(7、8)は、相互に密閉連結された少なくとも1つの容器(7)および少なくとも1つの浸潤注射器(8)を含むとともに、取り外し可能に第2の連結手段(9)に連結可能であり、脂肪が充填されると、脂肪アリコートを収容して注入する可搬ユニットを構成することを特徴とする脂肪吸引した脂肪をアリコートに分割するシステム。 - 前記注射装置(7、8)は、前記第2の連結手段(9)に取り外し可能な方法で連結できる取付手段(20)を含むことを特徴とする請求項1に記載のシステム(1)。
- 前記容器(7)は、第2の流路(11)を介して前記浸潤注射器(8)に密閉連結されることを特徴とする請求項1または2に記載のシステム(1)。
- 前記浸潤注射器(8)は、前記浸潤注射器自体に収容されている脂肪が前記容器(7)に向かって流出することを防止する少なくとも1つの単動バルブ(12)を含むことを特徴とする請求項1乃至3の何れか1項に記載のシステム(1)。
- 前記システムは、前記注射器具(7、8)を前記第2の連結手段(9)に連結させる分岐流路(10)を含み、該分岐流路は前記取付手段(20)と該第2の連結手段(9)との間に配置されることを特徴とする請求項1乃至4の何れか1項に記載のシステム(1)。
- 前記採取手段(2、3)は、脂肪物質を真空状態で密閉収容する容器に穿刺できる採取針(3)に連結された採取注射器(2)を含むことを特徴とする請求項1乃至5の何れか1項に記載のシステム(1)。
- 前記第1の連結手段は、前記注射器(2)と前記針(3)との間に配置されて該針(3)を該採取注射器(2)に連通させ、または後者を前記分離注射器(4)に連通させることのできる第1のバルブ手段(5)を含むことを特徴とする請求項6に記載のシステム(1)。
- 前記システムは、第3のバルブ手段(13)によって相互に並列に連結され前記第1および第2の連結手段(5、9)に前者の下流側且つ後者の上流側で直列に順に連結された複数の分離注射器(4)を含み、前記第3のバルブ手段(13)は、前記量の脂肪物質の各分の流入、および前記水様液体から分離された脂肪の流出を交互に行うことを特徴とする請求項1乃至7の何れか1項に記載のシステム(1)。
- 前記第2の連結手段は少なくとも1つの2方向コック(9)を含むことを特徴とする請求項1乃至8の何れか1項に記載のシステム(1)。
- 前記第3のバルブ手段は3方向コックの傾斜板(13)を含むことを特徴とする請求項8または9に記載のシステム(1)。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000227A ITMO20130227A1 (it) | 2013-08-02 | 2013-08-02 | Metodo e sistema per aliquotare grasso da liposuzione |
ITMO2013A000227 | 2013-08-02 | ||
PCT/IB2014/063634 WO2015015471A2 (en) | 2013-08-02 | 2014-08-01 | System and method to divide liposuction fat into aliquots |
Publications (2)
Publication Number | Publication Date |
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JP2016527971A JP2016527971A (ja) | 2016-09-15 |
JP6405380B2 true JP6405380B2 (ja) | 2018-10-17 |
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JP2016530665A Active JP6405380B2 (ja) | 2013-08-02 | 2014-08-01 | 脂肪吸引した脂肪をアリコートに分割するシステムおよび方法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US10260037B2 (ja) |
EP (1) | EP3027239B1 (ja) |
JP (1) | JP6405380B2 (ja) |
ES (1) | ES2721437T3 (ja) |
IT (1) | ITMO20130227A1 (ja) |
PL (1) | PL3027239T3 (ja) |
TR (1) | TR201906204T4 (ja) |
WO (1) | WO2015015471A2 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3027235A1 (en) | 2013-07-30 | 2016-06-08 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
ITMO20130227A1 (it) | 2013-08-02 | 2015-02-03 | Biomed Device Srl | Metodo e sistema per aliquotare grasso da liposuzione |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
ITUB20154668A1 (it) * | 2015-10-14 | 2017-04-14 | Mario Goisis | Dispositivo per la filtrazione del grasso estratto con procedure chirurgiche di liposuzione |
CN108676702B (zh) * | 2018-05-23 | 2021-10-15 | 上海蓓蕊医疗科技有限公司 | 一种提取装置及其操作方法 |
Family Cites Families (12)
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KR20120003961A (ko) * | 2001-12-07 | 2012-01-11 | 사이토리 테라퓨틱스, 인크. | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
EP1794055A1 (en) * | 2004-09-07 | 2007-06-13 | Smith and Nephew, Inc. | Methods and devices for sterile field transfer |
US8062286B2 (en) * | 2005-03-23 | 2011-11-22 | Shippert Ronald D | Tissue transplantation method and apparatus |
WO2006100651A1 (en) * | 2005-03-23 | 2006-09-28 | Biosafe S.A. | Integrated system for collecting, processing and transplanting cell subsets, including adult stem cells, for regenerative medicine |
DE102008004977A1 (de) * | 2008-01-17 | 2009-07-23 | Miltenyi Biotec Gmbh | Vorrichtung zur Entnahme von biologischem Material |
US8361042B1 (en) * | 2009-04-07 | 2013-01-29 | Ruben Gonzalez | Fat harvesting container |
EP2424463B1 (en) * | 2009-05-01 | 2016-12-28 | Bimini Technologies LLC | Systems, methods and compositions for optimizing tissue and cell enriched grafts |
IT1400069B1 (it) * | 2010-05-20 | 2013-05-17 | Tremolada | Dispositivo e metodo per la preparazione di tessuto, in particolare tessuto adiposo per trapianto ottenuto da materiale adiposo lobulare estratto tramite liposuzione |
US9109198B2 (en) * | 2011-04-29 | 2015-08-18 | General Electric Company | Automated systems and methods for isolating regenerative cells from adipose tissue |
WO2013111130A1 (en) * | 2012-01-23 | 2013-08-01 | Estar Technologies Ltd | A system and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma(prp) |
US20140207103A1 (en) * | 2012-09-20 | 2014-07-24 | Tissue Genesis, Inc. | Hand-held adipose processor and cell concentrator |
ITMO20130227A1 (it) | 2013-08-02 | 2015-02-03 | Biomed Device Srl | Metodo e sistema per aliquotare grasso da liposuzione |
-
2013
- 2013-08-02 IT IT000227A patent/ITMO20130227A1/it unknown
-
2014
- 2014-08-01 TR TR2019/06204T patent/TR201906204T4/tr unknown
- 2014-08-01 PL PL14759338T patent/PL3027239T3/pl unknown
- 2014-08-01 JP JP2016530665A patent/JP6405380B2/ja active Active
- 2014-08-01 EP EP14759338.8A patent/EP3027239B1/en active Active
- 2014-08-01 ES ES14759338T patent/ES2721437T3/es active Active
- 2014-08-01 WO PCT/IB2014/063634 patent/WO2015015471A2/en active Application Filing
- 2014-08-01 US US14/909,532 patent/US10260037B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3027239A2 (en) | 2016-06-08 |
ITMO20130227A1 (it) | 2015-02-03 |
TR201906204T4 (tr) | 2019-05-21 |
US10260037B2 (en) | 2019-04-16 |
US20160186125A1 (en) | 2016-06-30 |
EP3027239B1 (en) | 2019-01-30 |
JP2016527971A (ja) | 2016-09-15 |
WO2015015471A2 (en) | 2015-02-05 |
PL3027239T3 (pl) | 2019-07-31 |
ES2721437T3 (es) | 2019-07-31 |
WO2015015471A3 (en) | 2015-07-23 |
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