JP6306994B2 - Guide wire and guide wire manufacturing method - Google Patents

Description

  The present invention relates to a guide wire and a guide wire manufacturing method.

  The guide wire can be used for the treatment of a site where surgical operation is difficult, such as PTCA (Percutaneous Transluminal Coronary Angioplasty), or for the purpose of minimally invasive to the human body, Used to guide catheters used for examinations such as angiography. A guide wire used for PTCA surgery is inserted to the vicinity of the target vascular stenosis portion together with the balloon catheter with the tip of the guide wire protruding from the tip of the balloon catheter. Guide to near.

  The blood vessel is intricately curved, and the guide wire used to insert the balloon catheter into the blood vessel has moderate flexibility and resilience to bending, and pushability to transmit the proximal end operation to the distal end. In addition, torque transmission properties (collectively referred to as “operability”), tensile strength, kink resistance (bending resistance), and the like are required. Among these properties, as a structure for obtaining moderate flexibility and resilience, a structure having a double metal coil having flexibility for bending around a thin tip core material of the guide wire, or a core material of the guide wire There is one using a superelastic wire such as Ni-Ti (for example, see Patent Document 1). It is also known that a reinforcing material is separately provided at the tip of the core material in order to improve torque transmission.

  In addition, when used in PTCA surgery, the guide wire has been made to reduce the pushability by thinning the tip of the core material so as to avoid the penetration of the blood vessel wall and be used as safely as possible. In order to maintain sufficient tensile strength to avoid breakage, the cross-sectional area should not be reduced excessively. Furthermore, in the PTCA technique, the tip of the core material may be shaped. In order to facilitate this shaping, it is known to press the tip of the core material into a flat plate shape. This reduces the pushability of the tip and improves safety. However, torque transmission performance is remarkably lowered, and when the reinforcing material is provided separately, torque transmission is improved, but it is difficult to perform such shaping.

  As described above, with the conventional guide wire, it is difficult to coexist with ease of shaping at the tip and improvement in torque transmission to the tip while maintaining safe pushability and tensile strength. .

US Patent No. 7,785,274 B2

  An object of the present invention is to provide a guide wire that can be easily shaped at the distal end portion of the guide wire and has excellent torque transmission to the distal end portion, and a method for manufacturing the guide wire.

Such an object is achieved by the present inventions (1) to (9) below.
(1) A guide wire comprising a core wire having a long shape and a thin tip portion,
The tip portion includes at least one rod-like portion provided along the longitudinal direction of the core wire;
Projecting on the outer periphery of the rod-shaped portion, and having at least one plate-shaped portion having a thin plate shape smaller than the thickness of the rod-shaped portion,
The guide wire according to claim 1, wherein the rod-shaped portion has a circular cross-sectional shape .

  (2) The guide wire according to (1), wherein the rod-like portion and the plate-like portion are integrally formed.

  (3) The guide wire according to (1) or (2), wherein the two plate-like portions are provided via one rod-like portion.

  (4) The guide wire according to (1) or (2), wherein two rod-like portions are provided, and one plate-like portion is provided between the two rod-like portions.

  (5) The guide wire according to any one of (1) to (4), wherein an overall length of the rod-like portion and an overall length of the plate-like portion are the same.

(6) The guide wire according to any one of (1) to (5) , wherein the width of the plate-like portion is gradually increased or gradually decreased in the distal direction.

(7) The guide wire according to any one of (1) to (6) , wherein a thickness of the plate-like portion is constant along a longitudinal direction of the core wire.

(8) A method for producing a guide wire comprising a core wire having an elongated shape and a thin tip portion,
By at least one of pressurization and heating, the tip portion is provided along the longitudinal direction of the core wire, and protrudes from the outer peripheral portion of the rod-shaped portion, at least one rod-shaped portion having a circular cross-sectional shape. And at least one plate-like portion having a thin plate shape smaller than the thickness of the rod-like portion.

(9) For the formation of the tip portion, a mold including a cavity having a shape corresponding to the shape of the rod-like portion and the plate-like portion is used.
The said metal mold | die is a manufacturing method of the guide wire as described in said (8) in which at least one of the said pressurization and the said heating is possible.

  In the guide wire of the present invention, it is preferable that the distance between the two rod-shaped portions gradually increases in the distal direction.

  Moreover, in the guide wire of this invention, it is preferable that the full length of the said rod-shaped part is longer than the full length of the said plate-shaped part.

  Moreover, in the guide wire of this invention, it is preferable that the thickness of the said rod-shaped part is constant along the longitudinal direction of the said core wire.

  Moreover, in the guide wire of this invention, it is preferable that the width | variety of the said plate-shaped part is constant along the longitudinal direction of the said core wire.

  According to the present invention, the reshapable part has a rod-like part and a plate-like part thinner than that. As a result, it is easy to shape the tip of the guide wire (reshaping portion), and torque can be reliably transmitted to the tip, that is, the torque transmission is excellent. Moreover, since the cross-sectional area is the same, the tensile strength can be maintained.

FIG. 1 is a partial longitudinal sectional view showing a first embodiment of the guide wire of the present invention. FIG. 2 is a perspective view showing a reshape portion of a core wire included in the guide wire shown in FIG. FIG. 3 is a perspective view showing a process of manufacturing a core wire (reshaping part) included in the guide wire shown in FIG. FIG. 4 is a perspective view showing a reshape portion of a core wire included in the guide wire (second embodiment) of the present invention. FIG. 5 is a perspective view showing a reshape portion of a core wire included in the guide wire (third embodiment) of the present invention. FIG. 6 is a perspective view showing a reshape portion of a core wire included in the guide wire (fourth embodiment) of the present invention. FIG. 7 is a perspective view showing a reshape portion of a core wire included in the guide wire (fifth embodiment) of the present invention. FIG. 8 is a side view showing a reshape portion of a core wire included in the guide wire (sixth embodiment) of the present invention.

  Hereinafter, a guide wire and a guide wire manufacturing method according to the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIG. 1 is a partial longitudinal sectional view showing a first embodiment of the guide wire of the present invention. FIG. 2 is a perspective view showing a reshape portion of a core wire included in the guide wire shown in FIG. FIG. 3 is a perspective view showing a process of manufacturing a core wire (reshaping part) included in the guide wire shown in FIG. In the following, for convenience of explanation, the right side in FIGS. 1 and 2 (the same applies to FIGS. 4 to 7) is referred to as the “base end”, and the left side is referred to as the “tip”. In FIG. 1 and FIG. 2 (the same applies to FIGS. 4 to 7), the length direction of the guide wire is shortened and the thickness direction of the guide wire is exaggerated for easy understanding. The ratio between the length direction and the thickness direction is very different from the actual one.

  A guide wire 1 shown in FIG. 1 is a guide wire for a catheter that is used by being inserted into the lumen of a catheter (including an endoscope) by PTCA, for example. The total length of the guide wire 1 is not particularly limited, but is preferably about 200 to 5000 mm. The guide wire 1 includes a core wire (wire body) 2 composed of a single long wire, and a spiral coil 5 installed at the tip end portion (tip end portion) of the core wire 2. ing.

  The core wire 2 includes a reshapable portion 3 located on the distal end side and a main body portion 4 located on the proximal end side of the reshapable portion 3.

  The reshape portion 3 is a portion that can be reshaped (shaped) with a small diameter, located at the tip of the core wire 2, and is bent or bent in the direction of the arrow in FIGS. 1 and 2, for example. It can be used by bending. In general, in order to guide the distal end of a guide catheter or the like to a blood vessel shape, or to select and guide a blood vessel branch appropriately and smoothly, a doctor or the like previously sets the distal end of the guide wire to a desired shape. In this way, bending the tip of the guide wire into a desired shape is called reshaping. And by providing the reshape part 3, reshape can be performed easily and reliably, and the operativity at the time of inserting the guide wire 1 in a biological body improves markedly. In addition, the marker which shows the preferable bending direction of the said front-end | tip part may be attached | subjected to the front-end | tip part of the guide wire 1. FIG.

  The main body portion 4 is a portion that is thicker and longer than the reshape portion 3. The main body portion 4 has a tapered portion 41 having a tapered shape in which the outer diameter gradually increases in the proximal direction, and a constant outer diameter portion 42 having a constant outer diameter.

  By forming the taper portion 41 between the reshape portion 3 and the constant outer diameter portion 42, the rigidity (bending rigidity, torsional rigidity) of the core wire 2 can be gradually reduced toward the distal end. As a result, the guide wire 1 can obtain a good stenosis portion passing through and flexibility at the distal end portion, improve followability to a blood vessel and the like, and can be prevented from being bent. In addition, the taper angle (decrease rate of the outer diameter) of the taper portion 41 may be constant along the longitudinal direction of the core wire 2 or may have a portion that varies along the longitudinal direction. For example, a portion where a relatively large taper angle and a relatively small portion are alternately formed a plurality of times may be used.

  The outer diameter constant portion 42 has the same outer diameter as the maximum outer diameter of the tapered portion 41, and is a portion having relatively high rigidity. Thereby, the pushing property to the front-end | tip direction of the guide wire 1 becomes favorable. The base end surface 421 of the constant outer diameter portion 42 is preferably rounded.

  As shown in FIG. 1, a coil 5 is disposed on the outer periphery of the reshape portion 3 of the core wire 2 so as to cover the reshape portion 3. The coil 5 reduces the contact area of the surface of the core wire 2 with the inner wall of the catheter or the surface of the living body, thereby reducing sliding resistance, and as a result, the operability of the guide wire 1 is further improved.

  The reshape portion 3 is inserted through the central portion inside the coil 5, and the reshape portion 3 is not in contact with the inner surface of the coil 5. As a result, a gap 11 is formed between the coil 5 and the reshapable portion 3, and the pushability with respect to the blood vessel wall can be lowered.

  The coil 5 is formed by winding a wire 51 in a spiral shape along the circumferential direction of the reshapable portion 3. In this case, one strand 51 may be spirally wound, or a plurality of strands 51 may be spirally wound.

  In the present embodiment, adjacent strands 51 of the coil 5 are in contact with each other and are in a so-called dense winding state. These strands 51 generate a force (compression force) that pushes them in the axial direction of the core wire 2 in a natural state where no external force is applied. The guide wire 1 is not limited to this, and there may be a so-called sparsely wound portion where the adjacent strands 51 of the coil 5 are separated from each other.

  The constituent material of the strand 51 is not specifically limited, Any of a metal material and a resin material may be sufficient. Preferable examples of the metal material include X-ray opaque materials such as stainless steel, noble metals such as Au and Pt, and alloys containing the noble metals (for example, Pt—Ni alloys). When an X-ray opaque material is used, X-ray contrast properties are obtained at the distal end portion of the guide wire 1, and it can be inserted into the living body while confirming the position of the distal end portion under X-ray fluoroscopy.

  The coil 5 may be a combination of two or more materials. For example, the strand 51 on the distal end side of the coil 5 can be made of an X-ray opaque material such as the Pt—Ni alloy, and the strand 51 on the proximal end side of the coil 5 can be made of stainless steel. In this case, under X-ray fluoroscopy, the part located on the distal end side of the coil 5 (particularly, the part including the reshapable portion 3) can be emphasized more than the part located closer to the proximal end ( Therefore, the position of the most distal portion (the portion where the reshape portion 3 exists) of the guide wire 1 can be visually recognized more clearly.

  The wire diameter of the strand 51 of the coil 5 may be the same over the entire length of the coil 5, but the wire diameter of the strand 51 may be different between the distal end side and the proximal end side of the coil 5. For example, the wire diameter of the strand 51 may be smaller (or larger) on the distal end side of the coil 5 than on the proximal end side. Thereby, the softness | flexibility of the guide wire 1 in the front-end | tip part of the coil 5 can be improved more.

  The outer diameter of the coil 5 may be the same over the entire length of the coil 5, but the outer diameter of the coil 5 may be different between the distal end side and the proximal end side of the coil 5. For example, the outer diameter of the coil 5 may be smaller on the distal end side of the coil 5 than on the proximal end side. Thereby, the penetration of the lesioned part of the guide wire 1 at the distal end of the coil 5 can be further improved.

  As shown in FIG. 1, the coil 5 is fixed to the core wire 2 at two locations. That is, the distal end portion of the coil 5 is fixed to the distal end of the reshapable portion 3 via a fixing material (fixing portion) 52, and the proximal end portion of the coil 5 is located in the middle of the tapered portion 41 via the fixing material (fixing portion) 53. It is fixed. By fixing at a plurality of locations in this way, the coil 5 can be securely fixed to the core wire 2 while preventing the tip portion of the guide wire 1 (the portion where the coil 5 is present) from being impaired. it can.

  In particular, since the distal end side and the proximal end side of the reshape portion 3 are fixed by the fixing materials 52 and 53, respectively, the reshape portion 3 can be securely fixed to the coil 5, and the shape of the shaped reshape portion 3 can be secured. Can be held properly.

  Each of the fixing materials 52 and 53 is preferably made of solder (brazing material). In addition, the fixing materials 52 and 53 may be adhesives. Further, the method for fixing the coil 5 to the core wire 2 is not limited to the above-described fixing material, and for example, welding may be used.

  In order to prevent damage to the inner wall of a body cavity such as a blood vessel, it is preferable that the distal end surface 521 of the fixing material 52 is rounded.

  As shown in FIG. 1, a resin coating layer 6 that covers the whole (or a part) of the core wire 2 is provided at a portion closer to the base end side than the fixing material 53. The resin coating layer 6 can be formed for various purposes. As an example, the operability of the guide wire 1 is reduced by reducing the friction (sliding resistance) of the guide wire 1 and improving the slidability. May be improved.

  In order to reduce the friction (sliding resistance) of the guide wire 1, the resin coating layer 6 is preferably made of a material that can reduce friction as described below. Thereby, the frictional resistance (sliding resistance) with the inner wall of the catheter used together with the guide wire 1 is reduced, the slidability is improved, and the operability of the guide wire 1 in the catheter becomes better. Further, since the sliding resistance of the guide wire 1 is lowered, the guide wire 1 can be reliably prevented from being kinked (bent) or twisted when the guide wire 1 is moved and / or rotated in the catheter.

  Examples of materials that can reduce such friction include polyolefins such as polyethylene and polypropylene, polyvinyl chloride, polyesters (PET, PBT, etc.), polyamides, polyimides, polyurethanes, polystyrenes, polycarbonates, silicone resins, fluorine resins ( PTFE, ETFE, etc.) or a composite material thereof.

  The resin coating layer 6 may be a single layer or a laminate of two or more layers (for example, an inner layer made of a material that is more flexible than an outer layer).

  As shown in FIGS. 1 and 2, in the guide wire 1, the reshapable portion 3 is composed of a single rod-shaped portion 31 having a rod shape and two plate-shaped portions 32 having a plate shape. .

  In the reshape part 3, a rod-like part 31 and a plate-like part 32 are integrally formed, and furthermore, the body part 4 is also integrally formed. Thus, in this embodiment, each part which comprises the said core wire 2 is integrally formed in the core wire 2. As shown in FIG. Thereby, manufacture of the core wire 2 (guide wire 1) becomes easy.

  The constituent material of the core wire 2 is not particularly limited. For example, stainless steel (for example, SUS304, SUS303, SUS316, SUS316L, SUS316J1, SUS316J1L, SUS405, SUS430, SUS434, SUS444, SUS429, SUS430F, SUS302, and all other types of SUS. ), Various metal materials such as piano wire can be used, and among these, stainless steel is preferable.

  In addition to a material having relatively high rigidity such as stainless steel, a superelastic alloy exhibiting superelasticity in vivo can be used as a constituent material of the core wire 2. Superelastic alloys include any shape of the stress-strain curve caused by tension, including those that can significantly measure transformation points such as As, Af, Ms, and Mf, and those that cannot be deformed. However, everything that returns to its original shape by removing stress is included. The preferred composition of the superelastic alloy is Ni-Ti alloy such as Ni-Ti alloy of 49-52 atomic% Ni, Cu-Zn alloy of 38.5-41.5 wt% Zn, 1-10 wt% X Cu-Zn-X alloy (X is at least one of Be, Si, Sn, Al, and Ga), 36-38 atomic% Al-Ni-Al alloy, and the like. Among these, the Ni-Ti alloy is particularly preferable. When the core wire 2 is made of a superelastic alloy, heat treatment is performed on the portion of the core wire 2 that is to be the reshaped portion 3. Thereby, the physical property in the said part changes, ie, superelasticity reduces or lose | disappears, and the reshape part 3 which can be reshaped can be provided. In addition to the heat treatment, the portion may be cold worked. In addition, superelastic alloys represented by Ni—Ti alloys are excellent in adhesion to the resin coating layer 6.

  As described above, the reshapable part 3 is composed of one rod-like part 31 and two plate-like parts 32.

The rod-shaped portion 31 is provided on the central axis O _{2 of the} core wire 2 along the direction of the central axis O ₂ (longitudinal direction) of the core wire 2.

As shown in FIG. 3C, the cross-sectional shape of the rod-shaped portion 31 is circular, and its outer diameter φd ₃₁ (thickness) is constant along the central axis O ₂ . The outer diameter φd ₃₁ is the same as the minimum outer diameter of the tapered portion 41, and is preferably 0.05 mm or more and 0.2 mm or less, for example, 0.08 mm or more and 0.15 mm or less. Is more preferable.

  As shown in FIG. 2, each of the plate-like portions 32 is provided so as to protrude from the outer peripheral portion of the rod-like portion 31 and is in the form of a wing disposed on the both side surfaces via the rod-like portion 31. . Since the one plate-like portion 32 and the other plate-like portion 32 are the same except for the arrangement location, one plate-like portion 32 will be representatively described below.

As shown in FIG. 3C, the plate-like portion 32 has a thickness (thickness t ₃₂ ) that is smaller than the outer diameter φd ₃₁ of the rod-like portion 31. The thickness t ₃₂ is constant along the central axis O ₂ and is also constant in the width direction of the plate-like portion 32. The thickness t ₃₂ is preferably 10% or more and 60% or less of the outer diameter φd ₃₁ , and more preferably 15% or more and 35% or less.

The width _{w 32} of the plate-like portion 32 is constant along the central axis _{O 2.} The width w ₃₂ is preferably 10% or more and 200% or less of the outer diameter φd ₃₁ , and more preferably 40% or more and 90% or less.

  The rod-shaped portion 31 having such a shape has higher strength and rigidity than the plate-shaped portion 32. As a result, the rod-shaped portion 31 has a function of transmitting the pushing force to the tip of the guide wire 1 in addition to the torque from the main body portion 4 of the core wire 2 and others in the reshape portion 3.

  Each plate-like portion 32 is more flexible than the rod-like portion 31 and can be easily shaped by deformation. And in the state by which shaping was performed, each plate-shaped part 32 can each maintain the shape reliably in combination with the rod-shaped part 31.

  As described above, the guide wire 1 can be easily shaped at the distal end portion thereof, that is, the reshape portion 3, and has excellent torque transmission to the reshape portion 3.

Further, as shown in FIG. 2, in the present embodiment, the total length _{L 31} of the rod portion 31, and the total length _{L 32} of the plate portion 32 is the same. Thereby, the ease of bending of the reshapable portion 3 along the longitudinal direction thereof is constant, that is, the ease of bending is the same at any location in the longitudinal direction of the reshapable portion 3, thereby improving the operability during reshaping. . The total lengths L ₃₁ and L ₃₂ are, for example, preferably 2 mm or more and 100 mm or less, and more preferably 5 mm or more and 20 mm or less. With such a numerical range, the reshape portion 3 can be shaped without excess or deficiency.

  Next, a method of manufacturing the core wire 2 (guide wire 1) by processing the base material 2 'on which the reshape portion 3 has not yet been formed will be described with reference to FIG.

  As shown in FIG. 3, in this manufacturing method, the first mold 91 and the second mold 92 that can be closed (see FIG. 3B) and opened (see FIGS. 3A and 3C). A mold 9 provided with is used.

  The first mold 91 and the second mold 92 have a cavity 93 that molds the reshapable portion 3 in a closed state. That is, the first die 91 has a space 911, the second die 92 also has a space 921, and the spaces 911 and 921 communicate with each other in a closed state to form the reshape portion 3, that is, A cavity 93 having a shape corresponding to the shape of the rod-like portion 31 and each plate-like portion 32 can be formed.

  In the manufacture of the core wire 2, first, a base material 2 ′ having a main body portion 4 is prepared. At the tip end side of the taper portion 41 of the base material 2 ′, a reshape portion 3 is formed after molding, that is, a formation planned portion (reshape portion formation planned portion) 3 ′ for forming the reshape portion 3 projects integrally. Is formed. In the present embodiment, the planned formation portion 3 ′ has a circular cross-sectional shape and is a portion that is sufficiently thicker than the rod-shaped portion 31.

  Next, as shown in FIG. 3A, the formation planned portion 3 ′ is disposed between the first mold 91 and the second mold 92 in the mold open state.

  Next, the mold is closed as shown in FIG. At this time, heating may be performed while applying pressure. The heating is performed by a heating wire such as a nichrome wire built in at least one of the first die 91 and the second die 92, for example. Then, due to this pressurization and heating, the formation planned portion 3 ′ is melted while deforming and conforms to the shape of the cavity 93.

  Next, as shown in FIG. 3C, the mold is opened again. Thereby, the core wire 2 provided with the reshapable part 3 which has the one rod-shaped part 31 and the two plate-shaped parts 32 is obtained. As described above, the reshape portion 3 is easy to shape and has excellent torque transmission.

Second Embodiment
FIG. 4 is a perspective view showing a reshape portion of a core wire included in the guide wire (second embodiment) of the present invention.

  Hereinafter, the second embodiment of the guide wire and the guide wire manufacturing method of the present invention will be described with reference to this figure. However, the difference from the above-described embodiment will be mainly described, and the same matters will be described. Omitted.

  This embodiment is the same as the first embodiment except that the shape of the reshapable part is different.

As shown in FIG. 4, in this embodiment, the width w ₃₂ of each plate-like portion ₃₂ is gradually reduced toward the distal end direction. As a result, the rigidity (bending rigidity) of the reshape part 3 as a whole can be gradually reduced in the distal direction. It becomes easy to bend. This configuration is effective when the reshapable portion 3 is changing in bendability, that is, when it is desired to gradually increase or decrease the size (strength).

The reduction rate of the width w ₃₂ is constant along the central axis O ₂ in the illustrated configuration, but is not limited to this, and may vary along the central axis O ₂ .

  In addition, the reshapable portion 3 having such a shape can be formed by selecting a mold 9 having a cavity 93 that matches the shape.

<Third Embodiment>
FIG. 5 is a perspective view showing a reshape portion of a core wire included in the guide wire (third embodiment) of the present invention.

  Hereinafter, the third embodiment of the guide wire and the guide wire manufacturing method of the present invention will be described with reference to this figure. However, the description will focus on the differences from the above-described embodiment, and the same matters will be described. Omitted.

  This embodiment is the same as the first embodiment except that the shape of the reshapable part is different.

As shown in FIG. 5, in the present embodiment, the width w ₃₂ of each plate-like portion ₃₂ is gradually increased in the distal direction. As a result, the rigidity (bending rigidity) of the reshapable portion 3 as a whole can be gradually increased toward the distal end direction. It becomes easy. This configuration is effective when the reshapable portion 3 is changing in bendability, that is, when it is desired to gradually increase or decrease the size (strength).

The increase rate of the width w ₃₂ is constant along the central axis O ₂ in the illustrated configuration, but is not limited thereto, and may vary along the central axis O ₂ .

<Fourth embodiment>
FIG. 6 is a perspective view showing a reshape portion of a core wire included in the guide wire (fourth embodiment) of the present invention.

  Hereinafter, the fourth embodiment of the guide wire and the guide wire manufacturing method of the present invention will be described with reference to the drawings. However, the difference from the above-described embodiment will be mainly described, and the same matters will be described. Omitted.

  This embodiment is the same as the first embodiment except that the shape of the reshapable part is different.

As shown in FIG. 6, in the present embodiment, the length L ₃₁ of the rod-shaped part 31 is longer than the total length L ₃₂ of the plate portion 32, the plate-like portion 32 are localized in the distal end side. Thereby, in the reshape part 3, the part of the base end side on the opposite side to the plate-shaped part 32 becomes easier to bend than the part of the front end side where the plate-shaped part 32 is unevenly distributed. In this configuration, in the reshapable portion 3, the portion between the portion where the plate-like portion 32 is unevenly distributed and the portion where the plate-like portion 32 does not exist is used as a boundary portion, and the bending is easily performed on the distal end side and the proximal end side. This configuration is effective when it is desired to have a clear change, that is, a magnitude (strongness).

<Fifth Embodiment>
FIG. 7 is a perspective view showing a reshape portion of a core wire included in the guide wire (fifth embodiment) of the present invention.

  Hereinafter, the fifth embodiment of the guide wire and the guide wire manufacturing method of the present invention will be described with reference to the drawings. The fifth embodiment of the present invention will be described mainly with respect to differences from the above-described embodiments, and the same matters will be described. Omitted.

  The present embodiment is the same as the first embodiment except that the configuration of the reshapable part is different.

  As shown in FIG. 7, in the present embodiment, the reshapable portion 3 is composed of two rod-shaped portions 31 and one plate-shaped portion 32 provided between the two rod-shaped portions 31. . The reshapable portion 3 having such a configuration is higher in rigidity by one rod-shaped portion 31 and one plate-shaped portion 32 than the reshapable portion 3 in the first embodiment, and has a shape at the time of reshaping. Maintainability is also increased.

Further, the interval between the two rod-shaped portions 31 is gradually increased toward the distal end direction. As a result, the width w ₃₂ of the plate-shaped portion ₃₂ is gradually increased toward the distal end direction. Thereby, the reshapable part 3 can be deformed in the direction of arrow M1 in FIG. 7, and for example, the reshapable part 3 (plate-like part 32) is deformed in the direction of arrow M2 in FIG. It can be curved and deformed around _two times.

<Sixth Embodiment>
FIG. 8 is a side view showing a reshape portion of a core wire included in the guide wire (sixth embodiment) of the present invention.

  Hereinafter, the sixth embodiment of the guide wire and the guide wire manufacturing method of the present invention will be described with reference to this drawing. However, the difference from the above-described embodiment will be mainly described, and the same matters will be described. Omitted.

  This embodiment is the same as the first embodiment except that the shape of the reshapable part is different.

As shown in FIG. 8, in the present embodiment, each plate-like portion 32 is formed such that the thickness t ₃₂ changes, that is, the increase and decrease are alternately repeated. Thus, when deforming the reshapable portion 3, while preventing twisting of the central axis O ₂ around the reshapable portion 3 can be bent easily and reliably in the direction of the arrow in FIG.

  The guide wire and the guide wire manufacturing method of the present invention have been described above with respect to the illustrated embodiment. However, the present invention is not limited to this. Moreover, each part which comprises a guide wire can be substituted with the thing of the arbitrary structures which can exhibit the same function. Moreover, arbitrary components may be added.

  Further, the guide wire and the guide wire manufacturing method of the present invention may be a combination of any two or more configurations (features) of the above-described embodiments.

  In addition, the rod-shaped portion has an outer diameter that is constant along the longitudinal direction of the core wire, but is not limited thereto, and for example, the rod-shaped portion may have a portion where the outer diameter changes along the longitudinal direction of the core wire. .

  Further, the thickness of the plate-like portion is constant along the longitudinal direction of the core wire, but the present invention is not limited to this. For example, the plate-like portion may have a portion where the thickness changes along the longitudinal direction of the core wire. Good.

  In addition, the thickness of the plate-like portion is constant along the width direction of the plate-like portion, but is not limited to this. For example, the plate-like portion has a portion where the thickness changes along the width direction of the plate-like portion. You may do it.

  Further, when forming the reshaped part by processing the core material, one of pressurization and heating can be omitted depending on the mold used for the molding.

1 Guide wire 11 Gap 2 Core wire (Wire body)
2 'base material 3 reshape part 3' formation planned part (reshape part formation planned part)
31 Rod-shaped part 32 Plate-shaped part 4 Main body part 41 Tapered part 42 Constant outer diameter part 421 Base end face 5 Coil 51 Wire 52, 53 Fixing material (fixing part)
521 Tip surface 6 Resin coating layer 9 Mold 91 First mold 911 Space 92 Second mold 921 Space 93 Cavity φd ₃₁ Outer diameter L ₃₁ , L ₃₂ Total length M 1, M 2 Arrow O ₂ Center axis t ₃₂ Thickness w ₃₂ width

Claims (9)

A guide wire comprising a core wire having an elongated shape and a thin tip portion,
The tip portion includes at least one rod-like portion provided along the longitudinal direction of the core wire;
Wherein it protrudes to the outer periphery of the rod-like portion, possess at least one plate-like portion forming a small thin plate than the thickness of the rod-like portion,
The guide wire according to claim 1, wherein the rod-shaped portion has a circular cross-sectional shape .   The guide wire according to claim 1, wherein the rod-shaped portion and the plate-shaped portion are integrally formed.   The guide wire according to claim 1 or 2, wherein two plate-like portions are provided via one rod-like portion.   The guide wire according to claim 1 or 2, wherein two rod-like portions are provided, and one plate-like portion is provided between the two rod-like portions.   The guide wire according to any one of claims 1 to 4, wherein an overall length of the rod-like portion and an overall length of the plate-like portion are the same. The guide wire according to any one of claims 1 to 5 , wherein the width of the plate-like portion is gradually increased or gradually decreased in the distal direction. The guide wire according to any one of claims 1 to 6 , wherein the thickness of the plate-like portion is constant along the longitudinal direction of the core wire. A method for producing a guide wire comprising a core wire having an elongated shape and having a thin tip portion,
By at least one of pressurization and heating, the tip portion is provided along the longitudinal direction of the core wire, and protrudes from the outer peripheral portion of the rod-shaped portion, at least one rod-shaped portion having a circular cross-sectional shape. And at least one plate-like portion having a thin plate shape smaller than the thickness of the rod-like portion. For the formation of the tip portion, using a mold having a cavity having a shape corresponding to the shape of the rod-like portion and the plate-like portion,
The guide wire manufacturing method according to claim 8 , wherein the mold is capable of at least one of the pressurization and the heating.

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