JP6278426B2 - 温熱療法による治療のための管理された調合薬を調剤するシステムおよび方法 - Google Patents
温熱療法による治療のための管理された調合薬を調剤するシステムおよび方法 Download PDFInfo
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- 206010020843 Hyperthermia Diseases 0.000 title claims description 18
- 230000036031 hyperthermia Effects 0.000 title claims description 18
- 238000002360 preparation method Methods 0.000 title claims description 4
- 238000000034 method Methods 0.000 title description 16
- 238000011282 treatment Methods 0.000 title description 16
- 239000000203 mixture Substances 0.000 claims description 42
- 238000002156 mixing Methods 0.000 claims description 25
- 238000005485 electric heating Methods 0.000 claims description 23
- 239000003595 mist Substances 0.000 claims description 20
- 239000003186 pharmaceutical solution Substances 0.000 claims description 20
- 239000000443 aerosol Substances 0.000 claims description 16
- 239000006199 nebulizer Substances 0.000 claims description 16
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 239000011780 sodium chloride Substances 0.000 claims description 12
- 238000010438 heat treatment Methods 0.000 claims description 10
- 230000001066 destructive effect Effects 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 9
- 239000002504 physiological saline solution Substances 0.000 claims description 8
- 210000002345 respiratory system Anatomy 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 2
- 238000002664 inhalation therapy Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000003570 air Substances 0.000 description 36
- 239000000243 solution Substances 0.000 description 7
- 239000000825 pharmaceutical preparation Substances 0.000 description 6
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
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- 229940041682 inhalant solution Drugs 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010014405 Electrocution Diseases 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
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- 238000002474 experimental method Methods 0.000 description 1
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- 238000013021 overheating Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
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- 230000000241 respiratory effect Effects 0.000 description 1
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- 230000003068 static effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
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Description
システム10は、外側ハウジング13内に囲われている吸入モジュール12を有している。吸入モジュール12は、さらに垂直壁15を有している。壁15は外側ハウジング13内において垂直に、しかも典型的な形状としてはハウジング13の頂部から、ハウジング13の底部までは到達しないように延在していることが重要である。したがって、底部において壁15は少なくとも1つの肉厚部(butt-end)を形成するようにして終了し、この開口はハウジング13の底部から所定の距離をもって位置している。壁15は、以下に詳述するように、吸入蒸気と霧が形成される場所である吸入モジュール12の内部区画14を形成している。
システム10は、調合薬噴霧器モジュール20を有している。調合薬噴霧器モジュール20は、噴霧される調合薬の溶液あるいは生理的食塩水Sの上質のエーロゾルAを製造するために適用され、前記溶液はその後混合モジュール30に供給される。調合薬噴霧器モジュール20は、一般に、調合薬の溶液あるいは生理的食塩水Sを含んでいるが、いくつかの実施例においては、調合薬の溶液あるいは生理的食塩水Sは、分離している貯留器に収納され、噴霧器モジュール(図示せず)に供給される。システム10が、任意に異なる調合薬の溶液あるいは異なる生理的食塩水Sを積み込まれた多数の異なる調合薬噴霧器モジュール20を任意に有することは認められるべきである。
システム10は、混合モジュール30を有している。混合モジュール30の好ましい実施形態を説明するために、参照事項は今、図2および図3によりなされる。混合モジュール30は、吸入モジュール12からの混合物Mと、調合薬噴霧器モジュール20からのエーロゾルAとを受け入れ、混合物MをエーロゾルAに混合して、噴霧される調合薬の溶液あるいは生理的食塩水Sの投与と結びつけられる吸入剤Iの霧と蒸気による温熱療法による治療に好適な混合物M+Aを形成する。一方向だけに作用する逆止弁(図示せず)が、吸入モジュール12から混合モジュール30への調合薬の溶液あるいは生理的食塩水Sの逆流を防止するために吸入モジュール12と混合モジュール30との間に一般に配設されている。混合モジュール30は、好ましくは、ベンチュリ型の外形とされている。混合物Mは、吸入モジュール12からより広い断面を有するベンチュリ管の部分に供給される。混合モジュール30内に進むにつれてベンチュリ管の断面は狭くなり、その結果、流れは増大し、相対的に負圧が形成される。
温熱療法による治療と調合薬の投与に好適な混合物を用意するという本発明の方法の実施形態を可視化するため、参照事項は今、図4によりなされる。温熱療法による治療と調合薬の投与に好適な混合物を用意する工程は、空気流を製造するするための手段を駆動することを伴うステップ102から開始される。ステップ102において空気流を製造するするための手段を駆動することにより、空気流はステップ104において製造される。
Claims (2)
- 温熱療法の吸入療法と呼吸管の上部への調合薬の投与に好適な混合物を用意するシステムであって、
(a) 前記システムは、吸入モジュールを有し、この吸入モジュールは、
(i) 前記吸入モジュールを囲繞する外側ハウジングと、
(ii) 前記外側ハウジング内に配設された少なくとも1つの実質的に垂直な壁であって、この垂直壁の底部から前記ハウジングの底部までの距離は0より大きい垂直壁と、
(iii) 少なくとも1つの実質的に垂直な壁により画定され前記ハウジング内に位置する内部区画と、
(iv) 前記ハウジング内に含まれている吸入剤であって、前記壁の底部が吸入剤の上部液位より下方に配設されている吸入剤と、
(v) 前記内部区画の外部に配設されている空気流入口と、
(vi) 吸入剤を前記ハウジング内に供給するための吸入剤入口と、
(vii) 前記内部区画内に配設された出口と、
(viii) 吸入剤を加熱するための電気加熱要素と、を備えており、
前記電気加熱要素は、前記内部区画と本質的に同心状に配設され、
前記電気加熱要素は、前記壁の底部に隣接して配設され、
前記システムは、
(b) 低圧の空気流を発生するのに適合した送風機モジュールであって、前記吸入モジュールに接続され、この吸入モジュールに連続的に空気流を供給する送風機モジュールと、
(c) 前記内部区画内で製造された混合物を案内する可撓性を有するホースと、
(d) 前記ホースの末端にあるハンドピースと、
(e) 前記ハンドピースの先端にある少なくとも1つのノズルと、を備え、
前記送風機により形成される空気流は、前記ハウジングの空気流入口から、前記電気加熱要素の近傍において前記吸入剤を通過すると共に前記壁の底部の下方を越えて、前記内部区画内に流入し、
前記電気加熱要素の近傍において前記吸入剤を通過すると共に前記壁の底部の下方を越える流れは、前記電気加熱要素の近傍において前記空気流の増進された循環と共に前記吸入剤の増進された循環を形成し、これにより、前記システムは、前記電気加熱要素の近傍における前記空気流及び前記吸入剤の増進された循環により、前記電気加熱要素の増進された対流冷却及び前記吸入剤の蒸気の高い産出をなし、
前記電気加熱要素の近傍において前記吸入剤を通過すると共に前記壁の底部の下方を越える流れは、前記吸入剤の加熱されたエーロゾル霧を機械的に生産して前記空気流に混合し、
但し、前記電気加熱要素は、単一の加熱要素であって、複数の傾斜した加熱要素ではない。 - 前記システムは、霧化された調合薬溶液と霧化された生理的食塩水とにより構成された群から少なくとも1つ選択されたエーロゾルを製造するのに適合した噴霧器モジュールを更に備え、この噴霧器モジュールは、
(a) より高い圧力の圧縮空気を発生することができる空気圧圧縮機と、
(b) 非破壊タイプの噴霧器と、
(c) 調合薬溶液と生理的食塩水とにより構成された群から選択された少なくとも1つと、を有し、
(d) 前記システムは、混合モジュールを更に備え、この混合モジュールは、前記吸入モジュールと前記噴霧器モジュールとに接続され、前記吸入モジュールの生産物と前記噴霧器モジュールの生産物とを混合する、請求項1に記載の混合物を用意するためのシステム。
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