JP6200895B2 - 心筋薬剤送達装置および方法 - Google Patents
心筋薬剤送達装置および方法 Download PDFInfo
- Publication number
- JP6200895B2 JP6200895B2 JP2014543547A JP2014543547A JP6200895B2 JP 6200895 B2 JP6200895 B2 JP 6200895B2 JP 2014543547 A JP2014543547 A JP 2014543547A JP 2014543547 A JP2014543547 A JP 2014543547A JP 6200895 B2 JP6200895 B2 JP 6200895B2
- Authority
- JP
- Japan
- Prior art keywords
- drug
- delivery
- heart
- chamber
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
- A61B5/283—Invasive
- A61B5/287—Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/30—Input circuits therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6869—Heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0539—Anchoring of brain electrode systems, e.g. within burr hole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36064—Epilepsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3629—Heart stimulators in combination with non-electric therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
- A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
- A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
- A61N1/39622—Pacing therapy
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161629609P | 2011-11-21 | 2011-11-21 | |
US201161629599P | 2011-11-21 | 2011-11-21 | |
US61/629,609 | 2011-11-21 | ||
US61/629,599 | 2011-11-21 | ||
PCT/US2012/066156 WO2013078256A1 (fr) | 2011-11-21 | 2012-11-20 | Appareil et procédés d'administration de médicament myocardique |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017163500A Division JP6533811B2 (ja) | 2011-11-21 | 2017-08-28 | 心筋薬剤送達装置および方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014533584A JP2014533584A (ja) | 2014-12-15 |
JP6200895B2 true JP6200895B2 (ja) | 2017-09-20 |
Family
ID=48470274
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014543547A Expired - Fee Related JP6200895B2 (ja) | 2011-11-21 | 2012-11-20 | 心筋薬剤送達装置および方法 |
JP2017163500A Expired - Fee Related JP6533811B2 (ja) | 2011-11-21 | 2017-08-28 | 心筋薬剤送達装置および方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017163500A Expired - Fee Related JP6533811B2 (ja) | 2011-11-21 | 2017-08-28 | 心筋薬剤送達装置および方法 |
Country Status (8)
Country | Link |
---|---|
US (2) | US9107993B2 (fr) |
EP (2) | EP3195897B1 (fr) |
JP (2) | JP6200895B2 (fr) |
CN (1) | CN104159636B (fr) |
AU (3) | AU2012340751B2 (fr) |
CA (1) | CA2856404A1 (fr) |
ES (1) | ES2611405T3 (fr) |
WO (1) | WO2013078256A1 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11331424B2 (en) | 2009-01-26 | 2022-05-17 | Incube Labs, Llc | Apparatus, systems and methods for delivery of medication to the brain to treat neurological conditions |
US10159825B2 (en) | 2009-09-17 | 2018-12-25 | Zipline Medical, Inc. | Rapid closing surgical closure device |
WO2011159623A1 (fr) | 2010-06-14 | 2011-12-22 | Zipline Medical, Inc. | Procédés et appareil pour inhiber la formation de cicatrice |
US10123801B2 (en) | 2011-11-01 | 2018-11-13 | Zipline Medical, Inc. | Means to prevent wound dressings from adhering to closure device |
US9561034B2 (en) | 2011-11-01 | 2017-02-07 | Zipline Medical, Inc. | Surgical incision and closure apparatus |
EP3195897B1 (fr) | 2011-11-21 | 2019-01-02 | Incube Labs, LLC | Appareil d'administration de médicament myocardique |
BR112015005450B1 (pt) * | 2012-09-11 | 2021-03-02 | Native Cardiovascular Inc | dispositivo minimamente invasivo para liberação de drogas em tecido alvo |
EP3089677B1 (fr) | 2014-01-05 | 2020-04-01 | Zipline Medical, Inc. | Dispositif de fermeture de plaie à instrument |
CN108353237B (zh) * | 2015-10-30 | 2022-01-04 | 科利耳有限公司 | 可植入式刺激组件 |
US9867978B1 (en) * | 2016-09-16 | 2018-01-16 | Precision Neurotechnologies Llc | Conformal electrode arrays for electrophysiologic recording and neural stimulation within the cerebral ventricles |
WO2018081795A1 (fr) | 2016-10-31 | 2018-05-03 | Zipline Medical, Inc. | Systèmes et procédés de surveillance d'une thérapie physique du genou et d'autres articulations |
WO2019060298A1 (fr) | 2017-09-19 | 2019-03-28 | Neuroenhancement Lab, LLC | Procédé et appareil de neuro-activation |
US11717686B2 (en) | 2017-12-04 | 2023-08-08 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to facilitate learning and performance |
WO2019133997A1 (fr) | 2017-12-31 | 2019-07-04 | Neuroenhancement Lab, LLC | Système et procédé de neuro-activation pour améliorer la réponse émotionnelle |
US11364361B2 (en) | 2018-04-20 | 2022-06-21 | Neuroenhancement Lab, LLC | System and method for inducing sleep by transplanting mental states |
CA3100710A1 (fr) * | 2018-05-17 | 2019-11-21 | Massachusetts Institute Of Technology | Systeme pour stimulation electrique |
WO2019232035A1 (fr) * | 2018-05-31 | 2019-12-05 | University Of Virginia Patent Foundation | Système de distribution pour la régulation de l'écoulement de solution intraveineuse provenant de cathéters ramifiés vers un site sélectionné |
CN108837298B (zh) * | 2018-06-21 | 2020-05-22 | 浙江大学 | 一种皮下药物缓释装置 |
EP3593833A1 (fr) | 2018-07-13 | 2020-01-15 | Medtronic Inc. | Cathéter pour une meilleure dispersion de médicaments par voie intrathécale |
GB2574074B (en) | 2018-07-27 | 2020-05-20 | Mclaren Applied Tech Ltd | Time synchronisation |
EP3849410A4 (fr) | 2018-09-14 | 2022-11-02 | Neuroenhancement Lab, LLC | Système et procédé d'amélioration du sommeil |
US11786694B2 (en) | 2019-05-24 | 2023-10-17 | NeuroLight, Inc. | Device, method, and app for facilitating sleep |
GB2588236B (en) | 2019-10-18 | 2024-03-20 | Mclaren Applied Ltd | Gyroscope bias estimation |
US11344714B2 (en) * | 2019-11-04 | 2022-05-31 | Medtronic, Inc. | Intrathecal catheter with features to reduce drug dispersion |
Family Cites Families (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3885561A (en) * | 1971-12-15 | 1975-05-27 | Charles N Mazal Cami | Catheter |
US4829070A (en) * | 1982-05-18 | 1989-05-09 | University Of Florida | Novel redox carriers for brain-specific drug delivery |
US4994028A (en) * | 1987-03-18 | 1991-02-19 | Endocon, Inc. | Injector for inplanting multiple pellet medicaments |
US4950232A (en) * | 1987-08-11 | 1990-08-21 | Surelab Superior Research Laboratories | Cerebrospinal fluid shunt system |
US5170785A (en) | 1989-05-03 | 1992-12-15 | Dr. Eckhard Alt | Rate varying pacemaker apparatus and method for deriving a preferred one of different patient activity control signals |
US5152744A (en) * | 1990-02-07 | 1992-10-06 | Smith & Nephew Dyonics | Surgical instrument |
US5250034A (en) * | 1990-09-17 | 1993-10-05 | E-Z-Em, Inc. | Pressure responsive valve catheter |
US5181511A (en) | 1991-10-21 | 1993-01-26 | Telectronics Pacing Systems, Inc. | Apparatus and method for antitachycardia pacing using a virtual electrode |
IL116699A (en) | 1996-01-08 | 2001-09-13 | Biosense Ltd | Method of building a heart map |
US6023638A (en) | 1995-07-28 | 2000-02-08 | Scimed Life Systems, Inc. | System and method for conducting electrophysiological testing using high-voltage energy pulses to stun tissue |
US5846220A (en) * | 1996-04-30 | 1998-12-08 | Medtronic, Inc. | Therapeutic method for treatment of Alzheimer's disease |
US5713923A (en) | 1996-05-13 | 1998-02-03 | Medtronic, Inc. | Techniques for treating epilepsy by brain stimulation and drug infusion |
DE19638581A1 (de) | 1996-09-20 | 1998-03-26 | Biotronik Mess & Therapieg | Implantierbare Vorrichtung zur Tachykardie-Früherkennung und -Unterdrückung beim Herzen |
US6086582A (en) * | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
US5957901A (en) * | 1997-10-14 | 1999-09-28 | Merit Medical Systems, Inc. | Catheter with improved spray pattern for pharmaco-mechanical thrombolysis therapy |
US6227203B1 (en) | 1998-02-12 | 2001-05-08 | Medtronic, Inc. | Techniques for controlling abnormal involuntary movements by brain stimulation and drug infusion |
ATE386462T1 (de) | 1999-05-13 | 2008-03-15 | St Jude Medical Atrial Fibrill | Vorrichtung zum aufzeichnen des ursprungs von arrhythmien |
US6295476B1 (en) | 1999-11-01 | 2001-09-25 | Medtronic, Inc. | Medical lead conductor fracture visualization method and apparatus |
US6458118B1 (en) | 2000-02-23 | 2002-10-01 | Medtronic, Inc. | Drug delivery through microencapsulation |
US7031783B2 (en) * | 2001-06-29 | 2006-04-18 | Agilent Technologies, Inc. | Virtualized generic equipment model data and control router for factory automation |
US6974448B2 (en) * | 2001-08-30 | 2005-12-13 | Medtronic, Inc. | Method for convection enhanced delivery catheter to treat brain and other tumors |
US6950701B2 (en) | 2001-12-21 | 2005-09-27 | Medtronic, Inc. | Dual-chamber pacemaker system for simultaneous bi-chamber pacing and sensing |
US7164948B2 (en) | 2002-04-22 | 2007-01-16 | Medtronic, Inc. | Cardiac output measurement using dual oxygen sensors in right and left ventricles |
US20040019366A1 (en) | 2002-07-25 | 2004-01-29 | Rottenberg William B. | System and method for classification of cardiac activity using multiple sensing locations |
SE0202882D0 (sv) | 2002-09-30 | 2002-09-30 | St Jude Medical | An Implantable Heart Stimulator |
US20040215253A1 (en) | 2003-04-24 | 2004-10-28 | Weinberg Lisa P. | Implantable cardiac stimulation device providing atrial accelerated arrhythmia termination electrode configuration selection and method |
DE10332259A1 (de) * | 2003-07-16 | 2005-02-03 | Lurgi Bischoff Gmbh | Verfahren und Anlage zur Entschwefelung und Entstaubung von Abgasen, insbesondere Raffinerieabgasen |
US7142916B2 (en) | 2003-10-07 | 2006-11-28 | Medtronic, Inc. | Cardiac pacing modality having improved blanking, timing, and therapy delivery methods for extra-systolic stimulation pacing therapy |
EP1711222A4 (fr) | 2003-12-19 | 2011-02-09 | Savacor Inc | Electrode numerique de gestion du rythme cardiaque |
US20050137579A1 (en) * | 2003-12-23 | 2005-06-23 | Medtronic, Inc. | Permeable membrane catheters, systems, and methods |
US20050267556A1 (en) * | 2004-05-28 | 2005-12-01 | Allan Shuros | Drug eluting implants to prevent cardiac apoptosis |
US7272438B2 (en) | 2004-10-12 | 2007-09-18 | Pacesetter, Inc. | Mode switching heart stimulation apparatus and method |
US9186175B2 (en) | 2004-10-28 | 2015-11-17 | Nico Corporation | Surgical access assembly and method of using same |
US20060161211A1 (en) | 2004-12-31 | 2006-07-20 | Todd Thompson | Implantable accelerometer-based cardiac wall position detector |
US7308310B1 (en) | 2005-01-26 | 2007-12-11 | Pacesetter, Inc. | Implantable cardiac stimulation device providing bipolar autocapture and lead impedance assessment and method |
US7942864B2 (en) * | 2005-06-10 | 2011-05-17 | Hynes Richard A | Medical device including a catheter providing wound evacuation and medicine dispensing features and related methods |
US7937161B2 (en) | 2006-03-31 | 2011-05-03 | Boston Scientific Scimed, Inc. | Cardiac stimulation electrodes, delivery devices, and implantation configurations |
US8267905B2 (en) * | 2006-05-01 | 2012-09-18 | Neurosystec Corporation | Apparatus and method for delivery of therapeutic and other types of agents |
US20070275035A1 (en) * | 2006-05-24 | 2007-11-29 | Microchips, Inc. | Minimally Invasive Medical Implant Devices for Controlled Drug Delivery |
US8290600B2 (en) | 2006-07-21 | 2012-10-16 | Boston Scientific Scimed, Inc. | Electrical stimulation of body tissue using interconnected electrode assemblies |
US8311606B2 (en) | 2006-09-20 | 2012-11-13 | Cardiac Pacemakers Inc. | Conductive polymer patterned electrode for pacing |
JP2010514517A (ja) * | 2006-12-26 | 2010-05-06 | キューエルティー プラグ デリバリー,インク. | 視覚欠損の抑制のための薬物送達インプラント |
US7840267B2 (en) | 2007-03-23 | 2010-11-23 | Cardiac Pacemakers, Inc. | Closed-loop resynchronization therapy for mechanical dyssynchrony |
US20090131857A1 (en) | 2007-11-20 | 2009-05-21 | Mark Geiger | Method and apparatus for introducing a medicinal dose directly into a mammalian patient's cerebrospinal fluid |
EP2231254B9 (fr) * | 2007-12-11 | 2015-04-08 | Massachusetts Institute of Technology | Dispositif implantable d'administration de médicaments |
US9320877B2 (en) | 2009-03-20 | 2016-04-26 | Incube Labs, Llc | Solid drug delivery apparatus and formulations and methods of use |
US8644927B2 (en) | 2009-04-21 | 2014-02-04 | Incube Labs, Llc | Apparatus and method for the detection and treatment of atrial fibrillation |
CN102481438B (zh) | 2009-06-26 | 2013-09-18 | 塔里斯生物医药公司 | 可植入药物递送装置及制造所述装置的方法 |
US9554830B2 (en) * | 2010-02-25 | 2017-01-31 | Mayo Foundation For Medical Education And Research | Delivering drugs to desired locations within a mammal |
WO2012047931A1 (fr) | 2010-10-04 | 2012-04-12 | Massachusetts Institute Of Technology | Dispositif pour administration locale de médicament et traitement d'un œdème cérébral et autres maladies cérébrales |
EP3195897B1 (fr) | 2011-11-21 | 2019-01-02 | Incube Labs, LLC | Appareil d'administration de médicament myocardique |
-
2012
- 2012-11-20 EP EP16193365.0A patent/EP3195897B1/fr not_active Not-in-force
- 2012-11-20 EP EP12852050.9A patent/EP2782632B1/fr not_active Not-in-force
- 2012-11-20 JP JP2014543547A patent/JP6200895B2/ja not_active Expired - Fee Related
- 2012-11-20 CA CA2856404A patent/CA2856404A1/fr not_active Abandoned
- 2012-11-20 US US13/681,825 patent/US9107993B2/en not_active Expired - Fee Related
- 2012-11-20 WO PCT/US2012/066156 patent/WO2013078256A1/fr active Application Filing
- 2012-11-20 CN CN201280066560.6A patent/CN104159636B/zh not_active Expired - Fee Related
- 2012-11-20 AU AU2012340751A patent/AU2012340751B2/en not_active Ceased
- 2012-11-20 ES ES12852050.9T patent/ES2611405T3/es active Active
-
2013
- 2013-03-14 US US13/827,468 patent/US10507313B2/en not_active Expired - Fee Related
-
2017
- 2017-08-28 JP JP2017163500A patent/JP6533811B2/ja not_active Expired - Fee Related
- 2017-08-29 AU AU2017219161A patent/AU2017219161A1/en not_active Abandoned
-
2019
- 2019-01-17 AU AU2019200389A patent/AU2019200389A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US9107993B2 (en) | 2015-08-18 |
US20130267928A1 (en) | 2013-10-10 |
JP2014533584A (ja) | 2014-12-15 |
JP6533811B2 (ja) | 2019-06-19 |
ES2611405T3 (es) | 2017-05-08 |
US20130218124A1 (en) | 2013-08-22 |
AU2017219161A1 (en) | 2017-09-21 |
AU2019200389A1 (en) | 2019-02-07 |
WO2013078256A1 (fr) | 2013-05-30 |
EP3195897B1 (fr) | 2019-01-02 |
CN104159636B (zh) | 2017-05-03 |
EP2782632A4 (fr) | 2015-04-01 |
AU2012340751A1 (en) | 2014-06-19 |
JP2017202406A (ja) | 2017-11-16 |
CA2856404A1 (fr) | 2013-05-30 |
CN104159636A (zh) | 2014-11-19 |
EP2782632B1 (fr) | 2016-10-19 |
US10507313B2 (en) | 2019-12-17 |
AU2012340751B2 (en) | 2017-06-01 |
EP2782632A1 (fr) | 2014-10-01 |
EP3195897A1 (fr) | 2017-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6533811B2 (ja) | 心筋薬剤送達装置および方法 | |
US11478636B2 (en) | Tube-cut helical fixation anchor for electrotherapy device | |
US6129750A (en) | Fixation mechanism for a coronary venous pacing lead | |
US6931286B2 (en) | Delivery of active fixation implatable lead systems | |
JP2008521569A (ja) | 心膜腔にアクセスする方法及びシステム | |
US9987484B2 (en) | Method and system for lead delivery | |
US20120290053A1 (en) | Renal nerve stimulation lead, delivery system, and method | |
US20120290024A1 (en) | Transvenous renal nerve modulation for treatment of hypertension, cardiovascular disorders, and chronic renal diseases | |
US8942829B2 (en) | Trans-septal lead anchoring | |
US20100137927A1 (en) | Multifunctional cardiac pacemaker system | |
US9248271B2 (en) | Detection/stimulation microlead with enhanced positioning | |
US20220226642A1 (en) | Transvenous intracardiac pacing catheter | |
US9623235B1 (en) | Left ventricular lead with active fixation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20151102 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20161130 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170228 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20170727 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170828 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6200895 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |