JP6199050B2 - GPIb−フォン・ヴィレブランド因子相互作用の機能障害を有する試料を見出すためのスクリーニング方法 - Google Patents
GPIb−フォン・ヴィレブランド因子相互作用の機能障害を有する試料を見出すためのスクリーニング方法 Download PDFInfo
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- JP6199050B2 JP6199050B2 JP2013043157A JP2013043157A JP6199050B2 JP 6199050 B2 JP6199050 B2 JP 6199050B2 JP 2013043157 A JP2013043157 A JP 2013043157A JP 2013043157 A JP2013043157 A JP 2013043157A JP 6199050 B2 JP6199050 B2 JP 6199050B2
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- Japan
- Prior art keywords
- vwf
- protein
- gpibα
- solid phase
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/755—Factors VIII, e.g. factor VIII C [AHF], factor VIII Ag [VWF]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12158022.9A EP2637024A1 (de) | 2012-03-05 | 2012-03-05 | Screeningverfahren zum Auffinden von Proben mit einer Störung der Funktionalität der GPIb-Von Willebrand Faktor-Interaktion |
| EP12158022.9 | 2012-03-05 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013186124A JP2013186124A (ja) | 2013-09-19 |
| JP2013186124A5 JP2013186124A5 (enExample) | 2016-03-03 |
| JP6199050B2 true JP6199050B2 (ja) | 2017-09-20 |
Family
ID=47722189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013043157A Active JP6199050B2 (ja) | 2012-03-05 | 2013-03-05 | GPIb−フォン・ヴィレブランド因子相互作用の機能障害を有する試料を見出すためのスクリーニング方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9766234B2 (enExample) |
| EP (2) | EP2637024A1 (enExample) |
| JP (1) | JP6199050B2 (enExample) |
| ES (1) | ES2575778T3 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007031708A1 (de) * | 2007-07-06 | 2009-01-08 | Dade Behring Marburg Gmbh | Bestimmung der von Willebrand Faktor-Aktivität in Abwesenheit von Ristocetin |
| EP2637024A1 (de) | 2012-03-05 | 2013-09-11 | Siemens Healthcare Diagnostics Products GmbH | Screeningverfahren zum Auffinden von Proben mit einer Störung der Funktionalität der GPIb-Von Willebrand Faktor-Interaktion |
| EP2919013B1 (de) | 2014-03-11 | 2016-11-02 | Siemens Healthcare Diagnostics Products GmbH | Verfahren zur Detektion von Modulatoren der GPIb-Thrombin-Interaktion |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69940058D1 (de) * | 1998-04-23 | 2009-01-22 | Ajinomoto Kk | Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin |
| ES2358576T3 (es) | 1999-07-05 | 2011-05-11 | K.U. LEUVEN RESEARCH & DEVELOPMENT | Detección de la actividad del factor de von-willebrand (vwf). |
| DE102006019520A1 (de) * | 2006-04-27 | 2007-11-08 | Dade Behring Marburg Gmbh | Verfahren zur Bestimmung hoher Ristocetin-Kofaktor-Aktivitäten des von-Willebrand-Faktors |
| DE102007031708A1 (de) | 2007-07-06 | 2009-01-08 | Dade Behring Marburg Gmbh | Bestimmung der von Willebrand Faktor-Aktivität in Abwesenheit von Ristocetin |
| EP2193373A4 (en) | 2007-08-23 | 2010-07-28 | Bloodct Of Wisconsin Inc | METHODS AND KITS FOR MEASURING VON WILLEBRAND FACTOR |
| EP2637024A1 (de) | 2012-03-05 | 2013-09-11 | Siemens Healthcare Diagnostics Products GmbH | Screeningverfahren zum Auffinden von Proben mit einer Störung der Funktionalität der GPIb-Von Willebrand Faktor-Interaktion |
-
2012
- 2012-03-05 EP EP12158022.9A patent/EP2637024A1/de not_active Withdrawn
-
2013
- 2013-02-25 ES ES13156498.1T patent/ES2575778T3/es active Active
- 2013-02-25 EP EP13156498.1A patent/EP2637025B1/de active Active
- 2013-02-28 US US13/779,904 patent/US9766234B2/en active Active
- 2013-03-05 JP JP2013043157A patent/JP6199050B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013186124A (ja) | 2013-09-19 |
| ES2575778T3 (es) | 2016-07-01 |
| EP2637024A1 (de) | 2013-09-11 |
| EP2637025B1 (de) | 2016-04-13 |
| US9766234B2 (en) | 2017-09-19 |
| EP2637025A3 (de) | 2013-11-20 |
| EP2637025A2 (de) | 2013-09-11 |
| US20130230868A1 (en) | 2013-09-05 |
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