JP6196154B2 - Ｃ型肝炎ウイルス阻害剤の組み合わせ - Google Patents
Ｃ型肝炎ウイルス阻害剤の組み合わせ Download PDFInfo
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- JP6196154B2 JP6196154B2 JP2013523278A JP2013523278A JP6196154B2 JP 6196154 B2 JP6196154 B2 JP 6196154B2 JP 2013523278 A JP2013523278 A JP 2013523278A JP 2013523278 A JP2013523278 A JP 2013523278A JP 6196154 B2 JP6196154 B2 JP 6196154B2
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Classifications
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- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| JP2013535487A JP2013535487A (ja) | 2013-09-12 |
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| JP2016072377A Withdrawn JP2016155844A (ja) | 2010-08-06 | 2016-03-31 | Ｃ型肝炎ウイルス阻害剤の組み合わせ |
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| US (3) | US20120196794A1 (enExample) |
| EP (1) | EP2600835B1 (enExample) |
| JP (2) | JP6196154B2 (enExample) |
| KR (1) | KR101846596B1 (enExample) |
| CN (2) | CN103153280B (enExample) |
| AU (1) | AU2011285890B2 (enExample) |
| BR (1) | BR112013002922A2 (enExample) |
| CA (1) | CA2807589C (enExample) |
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| ES (1) | ES2685174T3 (enExample) |
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| US8329159B2 (en) | 2006-08-11 | 2012-12-11 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US20110269956A1 (en) | 2009-11-11 | 2011-11-03 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110274648A1 (en) | 2009-11-11 | 2011-11-10 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110281910A1 (en) | 2009-11-12 | 2011-11-17 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US8362020B2 (en) | 2009-12-30 | 2013-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US20120196794A1 (en) * | 2010-08-06 | 2012-08-02 | Bristol-Myers Squibb Company | Combinations of Hepatitis C Virus Inhibitors |
| BR112013004520A2 (pt) | 2010-08-26 | 2016-06-07 | Univ Emory | inibidores potentes e seletivos do virus da hepatite c |
| US8552047B2 (en) | 2011-02-07 | 2013-10-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9243025B2 (en) * | 2011-03-31 | 2016-01-26 | Idenix Pharmaceuticals, Llc | Compounds and pharmaceutical compositions for the treatment of viral infections |
| US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9546160B2 (en) | 2011-05-12 | 2017-01-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| CN104023726A (zh) | 2011-10-21 | 2014-09-03 | 艾伯维公司 | 用于治疗hcv的一种或多种daa的联合治疗(例如，与abt-072或abt-333) |
| DE112012003510T5 (de) * | 2011-10-21 | 2015-03-19 | Abbvie Inc. | Verfahren zur Behandlung von HCV umfassend mindestens zwei direkt wirkende antivirale Wirkstoffe, Ribavirin aber nicht Interferon |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| JP6154474B2 (ja) | 2012-10-19 | 2017-06-28 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｃ型肝炎ウイルス阻害剤 |
| EP2914613B1 (en) | 2012-11-02 | 2017-11-22 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| WO2014071007A1 (en) | 2012-11-02 | 2014-05-08 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| US9643999B2 (en) | 2012-11-02 | 2017-05-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| EP2914614B1 (en) | 2012-11-05 | 2017-08-16 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| EP2964664B1 (en) | 2013-03-07 | 2017-01-11 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| JP2016527232A (ja) | 2013-07-17 | 2016-09-08 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｈｃｖの治療に使用するためのビフェニル誘導体を含む組み合わせ |
| US10617675B2 (en) | 2015-08-06 | 2020-04-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| JP7129703B2 (ja) | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
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| MY140680A (en) * | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| US7456166B2 (en) * | 2006-05-17 | 2008-11-25 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
| US8329159B2 (en) * | 2006-08-11 | 2012-12-11 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2010042834A1 (en) * | 2008-10-09 | 2010-04-15 | Anadys Pharmaceuticals, Inc. | A method of inhibiting hepatitis c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds |
| US8415374B2 (en) * | 2009-10-12 | 2013-04-09 | Bristol-Myers Squibb Company | Combinations of hepatitis C virus inhibitors |
| US20120196794A1 (en) * | 2010-08-06 | 2012-08-02 | Bristol-Myers Squibb Company | Combinations of Hepatitis C Virus Inhibitors |
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2011
- 2011-08-01 US US13/195,317 patent/US20120196794A1/en not_active Abandoned
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- 2011-08-02 SG SG2013005905A patent/SG187193A1/en unknown
- 2011-08-02 WO PCT/US2011/046285 patent/WO2012018829A1/en not_active Ceased
- 2011-08-02 MX MX2013001170A patent/MX2013001170A/es unknown
- 2011-08-02 JP JP2013523278A patent/JP6196154B2/ja not_active Expired - Fee Related
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- 2011-08-02 AU AU2011285890A patent/AU2011285890B2/en not_active Ceased
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2013
- 2013-01-23 IL IL224369A patent/IL224369B/en not_active IP Right Cessation
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2014
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2015
- 2015-07-31 US US14/814,891 patent/US20150335655A1/en not_active Abandoned
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2016
- 2016-03-31 JP JP2016072377A patent/JP2016155844A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CN103153280B (zh) | 2015-09-09 |
| EA201390155A1 (ru) | 2013-05-30 |
| SG187193A1 (en) | 2013-03-28 |
| CA2807589A1 (en) | 2012-02-09 |
| AU2011285890B2 (en) | 2014-12-18 |
| ES2685174T3 (es) | 2018-10-05 |
| JP2016155844A (ja) | 2016-09-01 |
| MX2013001170A (es) | 2013-02-15 |
| IL224369B (en) | 2019-08-29 |
| US20120196794A1 (en) | 2012-08-02 |
| BR112013002922A2 (pt) | 2016-06-07 |
| CN103153280A (zh) | 2013-06-12 |
| KR20140002611A (ko) | 2014-01-08 |
| WO2012018829A1 (en) | 2012-02-09 |
| EP2600835A1 (en) | 2013-06-12 |
| SG2014008346A (en) | 2014-05-29 |
| CN105148275A (zh) | 2015-12-16 |
| JP2013535487A (ja) | 2013-09-12 |
| US20150335655A1 (en) | 2015-11-26 |
| EA022303B1 (ru) | 2015-12-30 |
| EP2600835A4 (en) | 2013-11-20 |
| KR101846596B1 (ko) | 2018-04-06 |
| AU2011285890A1 (en) | 2013-03-21 |
| CA2807589C (en) | 2016-08-30 |
| US20140235617A1 (en) | 2014-08-21 |
| EP2600835B1 (en) | 2018-05-30 |
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