JP6184327B2 - イメージング造影剤及びイメージング造影剤を使用するシステム - Google Patents
イメージング造影剤及びイメージング造影剤を使用するシステム Download PDFInfo
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- JP6184327B2 JP6184327B2 JP2013545552A JP2013545552A JP6184327B2 JP 6184327 B2 JP6184327 B2 JP 6184327B2 JP 2013545552 A JP2013545552 A JP 2013545552A JP 2013545552 A JP2013545552 A JP 2013545552A JP 6184327 B2 JP6184327 B2 JP 6184327B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/481—Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0883—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
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- Epidemiology (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
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Description
Claims (5)
- イメージング造影剤であって、
気泡と、
前記気泡から離れて自由浮遊する第1の光音響造影剤とを有し、
前記気泡は、前記第1の光音響造影剤によって放出される音響エネルギーを中継し、
前記イメージング造影剤は第2の光音響造影剤として機能する、
イメージング造影剤。 - イメージング造影剤と、
前記イメージング造影剤に含まれる音響エネルギー源の一つ以上の位置を特定する装置と、
を有するシステムであって、前記イメージング造影剤が、気泡と、前記気泡から離れて自由浮遊する光音響造影剤である前記音響エネルギー源とを有し、前記音響エネルギー源から放出される音響エネルギーが、前記気泡によって中継され、前記音響エネルギー源と前記気泡の間に物理的分離が存在し、前記装置が、前記中継されたエネルギーを受信するための機器を有するか、若しくは当該機器と通信可能に接続可能であり、前記位置特定は前記受信された中継されたエネルギーに基づく、システム。 - 前記装置が有する前記機器が、素子の空間分布を有する、イメージングアレイとして機能する超音波振動子アレイを含む、請求項2に記載のシステム。
- 前記機器に通信可能に接続されるための一つ以上の集積回路を有する、請求項2に記載のシステム。
- イメージング造影剤と、
複数の気泡から受信される超音波の時間遅延及び方向を使用して音響エネルギー源を位置特定する装置と、
を有するシステムであって、前記イメージング造影剤が、前記気泡と、前記気泡から離れて自由浮遊する光音響造影剤である前記音響エネルギー源とを有し、前記気泡は、前記受信される超音波として前記音響エネルギー源によって放出される音響エネルギーを中継し、前記装置が、前記中継された音響エネルギーを受信するための機器を有するか、若しくは当該機器と通信可能に接続可能であり、前記位置特定は前記受信された中継されたエネルギーに基づく、システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201061425808P | 2010-12-22 | 2010-12-22 | |
US61/425,808 | 2010-12-22 | ||
PCT/IB2011/055617 WO2012085751A1 (en) | 2010-12-22 | 2011-12-12 | Photo-acoustic signal enhancement with microbubble-based contrast agents |
Publications (2)
Publication Number | Publication Date |
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JP2014502533A JP2014502533A (ja) | 2014-02-03 |
JP6184327B2 true JP6184327B2 (ja) | 2017-08-23 |
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JP2013545552A Active JP6184327B2 (ja) | 2010-12-22 | 2011-12-12 | イメージング造影剤及びイメージング造影剤を使用するシステム |
Country Status (7)
Country | Link |
---|---|
US (1) | US10271733B2 (ja) |
EP (1) | EP2654551B1 (ja) |
JP (1) | JP6184327B2 (ja) |
CN (1) | CN103379850B (ja) |
BR (1) | BR112013015814A2 (ja) |
RU (1) | RU2013133959A (ja) |
WO (1) | WO2012085751A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2488097B1 (en) * | 2009-10-16 | 2021-01-13 | Koninklijke Philips N.V. | Photoacoustic contrast agent based active ultrasound imaging |
KR102255403B1 (ko) | 2013-07-21 | 2021-05-25 | 삼성메디슨 주식회사 | 결합된 광음향 및 초음파 진단 장치 및 방법 |
US9618445B2 (en) * | 2013-12-09 | 2017-04-11 | National Taiwan University | Optical microscopy systems based on photoacoustic imaging |
KR101654675B1 (ko) | 2014-02-03 | 2016-09-06 | 삼성메디슨 주식회사 | 광음향 물질을 이용하여 진단 영상을 생성하는 방법, 장치 및 시스템. |
US20160258904A1 (en) * | 2015-03-04 | 2016-09-08 | Bp Corporation North America Inc. | Process Control |
CN104984701B (zh) * | 2015-07-13 | 2017-06-27 | 中国科学院声学研究所 | 一种空化云微泡制备装置及其方法 |
Family Cites Families (18)
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US5250944A (en) * | 1990-10-29 | 1993-10-05 | Bio Medic Data Systems, Inc. | Antenna and driving circuit for transmitting and receiving images to and from a passive transponder |
GB9712524D0 (en) * | 1997-06-16 | 1997-08-20 | Nycomed Imaging As | Method |
US5977538A (en) * | 1998-05-11 | 1999-11-02 | Imarx Pharmaceutical Corp. | Optoacoustic imaging system |
US6317623B1 (en) * | 1999-03-12 | 2001-11-13 | Medrad, Inc. | Apparatus and method for controlling contrast enhanced imaging procedures |
US7367948B2 (en) | 2002-08-29 | 2008-05-06 | The Regents Of The University Of Michigan | Acoustic monitoring method and system in laser-induced optical breakdown (LIOB) |
EP1819277A4 (en) * | 2004-11-12 | 2010-05-05 | Ltd Kpe | NANOTE PARTICLE-MEDIATED ULTRASOUND THERAPY AND DIAGNOSTIC IMAGE DISPLAY |
EP2028994A1 (en) * | 2006-05-25 | 2009-03-04 | Koninklijke Philips Electronics N.V. | Photoacoustic imaging method |
US20070287983A1 (en) * | 2006-06-07 | 2007-12-13 | Richard Worthington Lodge | Absorbent article having an anchored core assembly |
CN1883379A (zh) * | 2006-06-09 | 2006-12-27 | 华南师范大学 | 光声脑功能成像的方法和装置 |
JP5432708B2 (ja) * | 2006-06-23 | 2014-03-05 | コーニンクレッカ フィリップス エヌ ヴェ | 光音響及び超音波合成撮像器のタイミング制御装置 |
US7896371B2 (en) * | 2007-07-13 | 2011-03-01 | Yamaha Hatsudoki Kabushiki Kaisha | All terrain vehicle with double wishbone suspension |
WO2009057021A2 (en) * | 2007-10-31 | 2009-05-07 | Koninklijke Philips Electronics N. V. | Photoacoustic imaging contrast agent and system for converting optical energy to in-band acoustic emission |
US20090156932A1 (en) | 2007-12-13 | 2009-06-18 | Board Of Trustees Of The University Of Arkansas | Device and method for in vivo flow cytometry using the detection of photoacoustic waves |
CN101214156B (zh) * | 2008-01-10 | 2010-12-15 | 复旦大学 | 声速不均匀介质热声成像的重建算法 |
WO2010020939A2 (en) | 2008-08-21 | 2010-02-25 | Koninklijke Philips Electronics, N.V. | Wireless ultrasound monitoring device |
WO2010024290A1 (ja) * | 2008-08-27 | 2010-03-04 | キヤノン株式会社 | 生体の光音響情報処理装置および生体の光音響情報処理方法 |
US20100285518A1 (en) * | 2009-04-20 | 2010-11-11 | The Curators Of The University Of Missouri | Photoacoustic detection of analytes in solid tissue and detection system |
EP2488097B1 (en) | 2009-10-16 | 2021-01-13 | Koninklijke Philips N.V. | Photoacoustic contrast agent based active ultrasound imaging |
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2011
- 2011-12-12 RU RU2013133959/14A patent/RU2013133959A/ru not_active Application Discontinuation
- 2011-12-12 BR BR112013015814A patent/BR112013015814A2/pt not_active IP Right Cessation
- 2011-12-12 CN CN201180068161.9A patent/CN103379850B/zh active Active
- 2011-12-12 WO PCT/IB2011/055617 patent/WO2012085751A1/en active Application Filing
- 2011-12-12 JP JP2013545552A patent/JP6184327B2/ja active Active
- 2011-12-12 US US13/995,711 patent/US10271733B2/en active Active
- 2011-12-12 EP EP11808717.0A patent/EP2654551B1/en active Active
Also Published As
Publication number | Publication date |
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EP2654551B1 (en) | 2020-05-27 |
JP2014502533A (ja) | 2014-02-03 |
RU2013133959A (ru) | 2015-01-27 |
CN103379850A (zh) | 2013-10-30 |
US20130281848A1 (en) | 2013-10-24 |
WO2012085751A1 (en) | 2012-06-28 |
US10271733B2 (en) | 2019-04-30 |
CN103379850B (zh) | 2015-11-25 |
BR112013015814A2 (pt) | 2018-05-15 |
EP2654551A1 (en) | 2013-10-30 |
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