JP6166760B2 - Body surface-mounted electrode, biological signal measuring method, and biological signal measuring device - Google Patents

Description

  The present invention relates to a body surface-mounted electrode that can be used as a biological electrode, a biological signal measuring method, and a biological signal measuring device including the body surface-mounted electrode.

  It is widely performed in the medical field and the health monitoring field to install electrodes on the surface of the skin and measure electrical signals generated from tissues such as the heart, muscle, and brain. As an electrode body of a body surface-mounted electrode used in these fields, a mesh or a metal plate made of a metal-coated fiber has been conventionally used. Since these electrode bodies do not have adhesiveness to the skin surface, means for fixing the electrode bodies to the skin surface is necessary. For example, an electrode body placed on the skin surface is covered with an adhesive tape and pasted (Non-Patent Document 1).

  When sweating occurs between the skin surface and the electrode body, the stratum corneum constituting the skin swells and the impedance (resistance) of the skin surface decreases, so that the detection of electrical signals by the electrode body is greatly affected (non-patented) References 1, 2). Conversely, detection of an electrical signal by the electrode body is also greatly affected when the skin surface dries and its impedance rises. For example, a drop in the impedance of the skin surface as it dries causes noise and decreases the detection level of the biological signal. If the gain of the device (amplifier) that amplifies the signal is increased accordingly, the signal-to-noise ratio (S / N ratio) will deteriorate.

  In the medical field or the like, a biological signal may be measured continuously for a day (24 hours), but the amount of perspiration changes depending on the activity of a patient (wearer) with an electrode installed. It will be a big problem. The amount of sweating does not depend only on changes in temperature, but even if the wearer stays in a room at a constant temperature, the amount of sweating (water vapor released from the skin) during daytime activities and during nighttime sleeping The amount) changes. For example, it is possible to measure stably because the wearer sweats moderately during daytime rest, but when body temperature falls at night and sweating stops, skin impedance rises, making it difficult to measure biological signals There is a case.

  The problem of dryness between the electrode body and the skin is particularly noticeable in a method (pasteless electrode) in which the electrode body is in direct contact with the skin surface. In order to prevent this dryness, a method of applying a wet paste (gel) containing an electrolyte between the skin surface and the electrode body may be employed depending on the purpose of the biosignal measurement. By applying the paste, it is possible to measure a signal in a low frequency region, which is an important component of a biological signal, which is difficult to detect in the case of pasteless, with high accuracy, and in a short time (for example, several tens of times). Min) can suppress the effects of sweating on the skin. However, if the paste is applied to the skin surface for a long period of time (for example, several hours to several tens of hours), the wearer not only feels uncomfortable, but the skin swells excessively, the skin becomes irritated, There is a problem that bacterial infection occurs.

Latest Trends in Various Biological Signal Recording Electrodes Medical Mechanics Vol80 No1 28-37 2010 Physiology Sympathetic skin reaction and its test method Lab Clin Prac 22 (1) 25-29 2004

  It is desirable that moderate moisture (humidity) is always present stably on the skin surface on which electrodes for detecting biological signals are installed. Therefore, there is a demand for a biological surface-mounted electrode that can stably maintain the humidity of the skin surface necessary for signal measurement without depending on the sweating from the skin.

  The present invention has been made in view of the above circumstances, and uses a biological surface-installed electrode that can stably maintain a moderately high humidity on the skin surface with which the electrode body contacts, and the biological surface-installed electrode. It is an object of the present invention to provide a biological signal measuring method and a biological signal measuring device including the biological surface-mounted electrode.

[1] A body surface-mounted electrode comprising an electrode main body having water permeability and a polymer gel impregnated with a liquid covering at least a part of the electrode main body. It can be illustrated as.
According to the body surface-mounted electrode, the liquid impregnated with the polymer gel keeps the humidity between the electrode body and the skin surface moderate. As a result, it is possible to stably detect a biological signal including a low frequency region, reduce discomfort of the wearer, and reduce the risk of dermatitis and bacterial infection.

[2] The body surface-installed electrode according to [1], wherein a protective sheet covering the polymer gel is provided, can be exemplified as a related invention.
According to the body surface-mounted electrode, since the protective sheet can suppress the evaporation of the liquid impregnated with the polymer gel, the humidity between the electrode body and the skin surface can be kept moderate for a longer time. it can. As a result, a biological signal including a low frequency region can be detected stably.

[3] A body surface-mounted electrode comprising an electrode body having water permeability, the electrode body having a conductive polymer, and the electrode body being impregnated with an ionic liquid.
According to the body surface-mounted electrode, the ionic liquid impregnated in the electrode body keeps the humidity between the electrode body and the skin surface moderate. As a result, it is possible to stably detect a biological signal including a low frequency region, reduce discomfort of the wearer, and reduce the risk of dermatitis and bacterial infection.

[4] The body surface-mounted electrode as set forth in any one of [1] to [3], wherein a conductive polymer is used as a material constituting the electrode body. It can be illustrated.
According to the body surface-mounted electrode, since the conductive polymer is contained in the electrode body, the hydrophilicity, water permeability, and affinity for the skin surface of the electrode body can be improved. As a result, a biological signal can be detected with higher accuracy.

[5] The body surface-mounted electrode according to [1], [2], or [4], wherein a conductive mesh is disposed between the electrode body and the polymer gel. Can be exemplified as related inventions.
According to the body surface-mounted electrode, the biological signal detected by the electrode body can be more easily transmitted to the external device through the conductive mesh. As a result, a biological signal can be detected with higher accuracy and more easily.

[6] The body surface-mounted electrode according to [2], wherein a material that does not transmit liquid and transmits water vapor is used as a material constituting the protective sheet. It can be illustrated as an invention.
According to the body surface installation type electrode, it is possible to avoid the skin surface on which the body surface installation type electrode is installed from being excessively swollen due to stuffiness. As a result, the discomfort of the wearer can be reduced, and the risk of dermatitis and bacterial infection can be reduced.

[7] Measurement of a biological signal, wherein the body surface-mounted electrode according to any one of [1] to [6] is installed on a skin surface of a living body, and an electrical signal of the living body is measured. Method.
In the measurement method, since the body surface-installed electrode is used, the humidity between the electrode body and the skin surface can be kept moderate, and a biological signal including a low frequency region can be detected stably, and the wearer Can reduce the discomfort and reduce the risk of dermatitis and bacterial infection.

[8] A biological signal measuring device comprising the body surface-mounted electrode according to any one of [1] to [6].
A body signal can be measured by installing the body surface-mounted electrode provided in the body signal measuring device on the body surface. At this time, the humidity between the electrode body and the skin surface can be kept at a moderate level, and it is possible to stably detect biological signals including the low frequency region, reduce wearer discomfort, and risk of dermatitis and bacterial infection. Can be reduced.

  According to the body surface-mounted electrode of the present invention, the liquid provided in the electrode is brought into contact with the skin surface through the moisture permeable electrode body, so that an appropriate wet state is provided between the electrode body and the skin surface. In addition, fluctuations in skin impedance due to sweat gland activity are suppressed, and stable biological signal measurement becomes possible. In particular, it is possible to record a biological signal with less noise by suppressing an increase in the impedance of the skin due to dryness in a low-temperature environment where the amount of sweating decreases or during sleep.

(A) It is a cross-sectional schematic diagram of the body surface installation type electrode of 1st embodiment of this invention. (B) It is a cross-sectional schematic diagram of the body surface installation type electrode of 2nd embodiment of this invention. (Top) It is a chart which shows the time-dependent change of the heart rate measured using 10 A of body surface installation type electrodes of 1st embodiment of this invention. (Lower) It is a chart which shows the time-dependent change of the heart rate measured using the electrode of a comparative example. Measurement has been interrupted (arrow) due to increased skin impedance during nighttime sleep. It is the Holter electrocardiogram waveform measured using the body surface installation type electrode of 2nd embodiment of this invention. The vertical waveform shown on the left shows changes in heart rate over time, and the horizontal waveform shown on the right is a compressed waveform of the electrocardiogram.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings, but the present invention is not limited to such embodiments.

《Body surface installation type electrode》
[First embodiment]
As shown in FIG. 1A, the body surface-mounted electrode according to the first embodiment of the present invention is impregnated with a liquid that covers the electrode body 1 having water permeability and at least a part of the electrode body 1. A body surface-installed electrode 10 </ b> A including a polymer gel 2 and an electrode body 1, an electrode body 1, and a protective sheet 3 covering the polymer gel 2.

  The electrode body 1 is in direct contact with the surface S of the skin. Since the water vapor and sweat (moisture) emitted from the skin are absorbed by the electrode main body 1 having water permeability, it is possible to prevent excessive steaming between the electrode main body 1 and the surface S of the skin. In addition, since the liquid impregnated in the polymer gel 2 diffuses (penetrates) into the electrode body 1 and reaches the skin surface S, it is possible to prevent the space between the electrode body 1 and the skin surface S from becoming dry. . As described above, since the wet state between the electrode body 1 and the skin surface S is kept moderately high, a weak biological signal can be detected from the skin surface S by the electrode body 1 with high accuracy.

  Since the electrode body 1 is in contact with the skin surface S, when the skin surface S before the electrode is placed (mounted) is dry, moisture or the liquid is transferred from the electrode body 1 to the skin surface S. To moisturize the surface S of the skin. At this time, the electrode body 1 loses moisture and the liquid, but at the same time, the liquid impregnated in the polymer gel 2 is supplied to the electrode body 1, so that the electrode body 1 is not dried. .

  Thus, by providing the polymer gel 2 impregnated with the liquid on the electrode body 1, the humidity of the surface S of the skin that is in contact with the electrode body 1 is kept moderately high for a long time (skin Can be suppressed). Applications where this effect is particularly effective include, for example, wearing to people who are placed in an environment where sweating is suppressed (for example, a low temperature environment), wearing to people who are less sweating physically, and people with thick keratinous skin And the like, and the like, and the like for a patient who has a tendency to keratinize the skin such as psoriasis.

In the present embodiment, a conductive mesh 4 is disposed between the electrode body 1 and the polymer gel 2. The conductive mesh 4 is connected to an external device by wiring (not shown).
By passing through the conductive mesh 4, a weak biological signal detected by the electrode body 1 can be stably transmitted to an external device.

In the present embodiment, a laminate in which the electrode body 1, the conductive mesh 4, and the polymer gel 2 are laminated in this order is placed on the surface S of the skin, and further, the protective sheet 3 covers them.
The protective sheet 3 covers not only the laminate, but also the skin surface S around the laminate.
For this reason, the laminate is almost sealed in a space surrounded by the protective sheet 3 and the skin surface S. In this semi-sealed state, the drying speed of the laminate can be reduced, and the humidity between the electrode body 1 and the skin surface S can be kept relatively high for a long time. it can.

  Thus, the size of the protective sheet 3 is such that it can cover the entire electrode body 1 or larger than the entire electrode body 1 and can cover the surrounding skin where the electrode body 1 is installed. The size is preferred.

  Examples of the material of the protective sheet 3 include a polyethylene sheet. Moreover, as a preferable material of the protection sheet 3, the material (moisture-permeable waterproof material) which has a function which does not permeate | transmit a liquid and permeate | transmits water vapor | steam is mentioned. By allowing the water vapor to pass through the protective sheet 3, the sealed space can be prevented from being steamed, and the electrode can be worn for a long time without causing the wearer to feel uncomfortable. Further, since the liquid does not permeate the protective sheet 3, it is possible to prevent the liquid impregnated in the polymer gel 2 from leaching out of the protective sheet 3.

  As a commercially available sheet material (moisture-permeable waterproof material) that is not permeable to liquid and permeates water vapor, which can be applied as a material for the protective sheet 3, for example, Entrant (registered trademark) (manufactured by Toray Industries, Inc.), GORE Examples include TEX (registered trademark) (distributor: Nippon Gore Co., Ltd.), DiAPLEX (registered trademark) (distributor: Mitsubishi Corporation).

  The material constituting the electrode body 1 is not particularly limited as long as it is a material having conductivity and water permeability. Here, the “water permeability” is a property that may not only transmit a liquid such as water but also include a property of absorbing and retaining a liquid such as water.

  The material constituting the electrode body 1 is preferably a conductive polymer, and more preferably a hydrophilic conductive polymer. For example, PEDOT-PSS or PEDOT-S is suitable as the conductive polymer having excellent conductivity and hydrophilicity. Moreover, polyaniline sulfonic acid, polypyrrole, etc. can be illustrated.

  PEDOT-PSS is a conductive polymer obtained by polymerizing 3,4-ethylenedioxythiophene as a monomer in the presence of poly (4-styrenesulfonic acid). PSS functions as a dopant that imparts a negative charge to PEDOT. Examples of commercially available PEDOT-PSS include Clevios P (manufactured by Heraeus, Germany). From the viewpoint of increasing the conductivity of the electrode body 1, the conductive polymer preferably contains a dopant.

  The shape of the electrode body 1 is not particularly limited, and may be appropriately designed according to the type of biological signal to be measured and the state of the body surface to be installed. Examples of the shape of the electrode body 1 include a plate shape such as a rectangle, a circle, an ellipse, and a polygon, a rod shape, and a line shape.

  When a conductive polymer is used as the material constituting the electrode body 1, the electrode body 1 may be composed of only the conductive polymer, or the electrode body 1 is supported or impregnated with the conductive polymer on the support member. May be configured. By using the support member, the structural strength of the electrode body 1 can be increased as compared with the electrode body 1 made of only a conductive polymer.

The support member is preferably a water permeable fabric.
Examples of the fabric include a woven fabric or a nonwoven fabric composed of conventionally known fibers such as cotton, silk, hemp, rayon, natural fiber, and chemical fiber. The shape and thickness of the fabric are not particularly limited.

  A method for forming the electrode body 1 by loading or impregnating the support member with a conductive polymer is not particularly limited. For example, preparing a solution in which a conductive polymer is dissolved or dispersed in an appropriate solvent, applying or impregnating the solution to a support member, removing the solvent, and fixing the conductive polymer to the support member Thus, the electrode body 1 can be manufactured.

  The method for fixing the conductive polymer to the support member is not particularly limited. For example, after the solution is applied to the support member, the solvent of the solution is evaporated, so that the conductive polymer is attached to the support member. And a method of drying and fixing. In addition, as other fixing methods applicable, electrochemical fixing, an organic solvent in which a monomer constituting the conductive polymer is contained in the solution, and the conductive polymers are electrochemically cross-linked through the monomer. Chemical fixing that contacts and fixes the solution after applying magnesium or magnesium, adhesive (such as acrylic resin) is preliminarily included in the solution, and the adhesive is solidified and the conductive polymer is contained in the adhesive. Examples of the method include embedding and fixing.

  The polymer gel 2 may cover a part of the electrode body 1 or the entire electrode body 1. By covering the electrode body 1, the polymer gel 2 functions as a moisture retaining pad.

  The material constituting the polymer gel 2 is not particularly limited as long as it is a material that can be impregnated with the liquid that moistens between the electrode body 1 and the surface S of the skin, and constitutes a known gel (gel) made of a polymer. The material to be applied is applicable. Examples of the gel made of such a high molecular polymer include a hydrogel containing a hydrophilic high molecular polymer. Examples of such a hydrogel material include polyvinyl alcohol, polyethylene oxide, polyvinyl pyrrolidone, and sodium polyacrylate.

  The thickness of the polymer gel 2 laminated on the electrode body 1 is not particularly limited, and examples thereof include 0.5 to 10 times the thickness of the electrode body 1. Specifically, for example, when the thickness of the electrode body 1 is 1 mm to 10 mm, the thickness of the polymer gel 2 can be set to 0.5 mm to 100 mm. Here, the thickness of the polymer gel 2 is a thickness at the time of swelling impregnated with the liquid.

  The liquid impregnated by the polymer gel 2 is not particularly limited as long as it can be impregnated into the polymer gel 2 and can diffuse into the electrode body 1 and moisten the space between the electrode body 1 and the skin surface S. Not. Examples of the liquid include water, glycerol, ionic liquid, and other conventionally known moisturizing liquids. Among these, glycerol or ionic liquid is preferable from the viewpoint of further improving the moisture retention.

  Examples of the ionic liquid include compounds having imidazolium, pyrrolidinium, piperidinium, pyridinium ammonium, and phosphonium.

More specifically,
1-butyl-3-methylimidazolium bis (trifluoromethanesulfonyl) imide (1-Butyl-3-methylimidazolium bis (trifluoromethanesulfonyl) imide),
1-butyl-3-methylimidazolium dicyanamide (1-Butyl-3-methylimidazolium dicyanamide),
1-butyl-3-methylimidazolium tetrafluoroborate (1-Butyl-3-methylimidazolium tetrafluoroborate),
1-butyl-3-methylimidazolium trifluoromethanesulfonate (1-Butyl-3-methylimidazolium trifluoromethanesulfonate),
1-butyl-1-methylpiperidinium tetrafluoroborate (1-Butyl-1-methylpiperidinium tetrafluoroborate),
1-butyl-1-methylpyrrolidinium tetrafluoroborate (1-Butyl-1-methylpyrrolidinium tetrafluoroborate),
1-butylpyridinium tetrafluoroborate (1-Butylpyridinium tetrafluoroborate (1 = N)),
Choline bis (trifluoromethylsulfonyl) imide,
Choline dihydrogen phosphate,
N, N-diethyl-N-methyl-N- (2-methoxyethyl) ammonium bis (trifluoromethanesulfonate)
(N, N-Diethyl-N-methyl-N- (2-methoxyethyl) ammonium bis (trifluoromethanesulfonate),
N, N-diethyl-N-methyl-N- (2-methoxyethyl) ammonium tetrafluoroborate (N, N-Diethyl-N-methyl-N- (2-methoxyethyl) ammonium tetrafluoroborate),
1-ethyl-3-methylimidazolium tetrafluoroborate (1-Ethyl-3-methylimidazolium tetrafluoroborate),
1-ethyl-3-methylimidazolium acetate (1-Ethyl-3-methylimidazolium acetate),
1-ethyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide (1-Ethyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide),
1-ethyl-3-methylimidazolium dicyanamide (1-Ethyl-3-methylimidazolium dicyanamide),
1-ethyl-1-methylpyrrolidinium tetrafluoroborate (1-Ethyl-1-methylpyrrolidinium tetrafluoroborate),
1-hexyl-3-methylimidazolium tetrafluoroborate (1-Hexyl-3-methylimidazolium tetrafluoroborate),
1-Butyl-1-methyl-pyrrolidinium tetracyanoborate,
1-ethyl-3-methyl-imidazolium tetracyanoborate,
1-butyl-3-methyl-imidazolium tricyanomethide,
N-butyl-3-methyl-imidazolium dicyanamide,
1-Ethyl-3-methylimidazolium amino acids
And the like.

  Among the above compounds, water-soluble 1-butyl-3-methylimidazolium dicyanamide and 1-butyl-3-methylimidazolium trifluoromethanesulfonate are preferable.

  The material which comprises the electroconductive mesh 4 arrange | positioned between the electrode main body 1 and the polymer gel 2 is not restrict | limited in particular, For example, the nylon thread | yarn (silver coat nylon thread | yarn) by which silver was coated is mentioned. By using a mesh material woven with silver-coated nylon yarn, a biological signal detected by the electrode body 1 can be easily transmitted to an external device. The mesh opening and the aperture ratio of the mesh are not particularly limited as long as the water vapor, water, and the liquid that diffuse between the electrode body 1 and the polymer gel 2 are permeable.

[Second Embodiment]
The body surface-mounted electrode according to the second embodiment of the present invention includes an electrode body 5 having water permeability as shown in FIG. 1 (B), and the electrode body 5 is impregnated with water, glycerol, or an ionic liquid. It is the body surface installation type electrode 10B characterized by having.

  The body surface installed electrode 10B of the second embodiment is different from the body surface installed electrode 10A of the first embodiment in that the polymer gel 2 is not used in the second embodiment. The same code | symbol is attached | subjected to the same structure as the structure of 1st embodiment, and the description is abbreviate | omitted.

  The electrode body 5 of the second embodiment is impregnated with water, glycerol or ionic liquid in advance. Unlike the first embodiment, since the polymer gel 2 is not provided, the electrode body 5 is relatively easier to dry than the electrode body 1 of the first embodiment. For this reason, it is suitable for the purpose of being used in a relatively short time. Further, since the configuration of the entire electrode is simpler, the configuration of the second embodiment is suitable when a thinner electrode is required.

  The electrode body 5 of the second embodiment can be manufactured by the same method using the same material as the electrode body 1 of the first embodiment.

<Measurement method of biological signal>
The biological signal measuring method according to the third embodiment of the present invention is a method of measuring the electrical signal of a living body to be measured by installing the body surface-mounted electrode of the first embodiment or the second embodiment on the surface of the living body. is there. The electrical signal can be detected and analyzed by connecting an electrode body or a conductive mesh provided on the body surface-mounted electrode to an external device. The external device is not particularly limited as long as it has a function of analyzing or recording a biological signal transmitted from the electrode, and examples thereof include a known heart rate monitor, electrocardiograph, electroencephalograph, and electromyograph. .

<Biosignal measurement device>
The biological signal measuring device according to the fourth embodiment of the present invention is a device provided with the body surface-mounted electrode according to the first embodiment or the second embodiment. The biological signal measuring device preferably includes an external device having a function of analyzing or recording a biological signal transmitted from the electrode in addition to the body surface-mounted electrode. Examples of the external device include a known heart rate monitor, electrocardiograph, electroencephalograph, and electromyograph.

[Example 1]
The body surface-mounted electrode of the first embodiment was prepared, the electrode was placed on the stratum corneum of the skin epidermis, and the electrode and the surrounding skin were covered with a moisture-permeable waterproof sheet. In this state, the heart rate of an adult male was continuously measured for 17 hours or more. The result is shown in the chart of FIG. The horizontal axis of the chart indicates time (time), and the vertical axis indicates heart rate (beats / minute). The heart rate was recorded using a heart rate monitor RS800CX (manufactured by Polar).
As shown in the chart, the change in heart rate could be measured stably from 23:00 on the measurement start day to 16:00 on the next day.

Specifically, the body surface-mounted electrode of Example 1 was produced as follows.
As an electrode body (electrode pad), conductive polymer PEDOT-PSS (trade name: Clevios P, manufactured by Heraeus, Germany) is impregnated into 4 x 5 cm polyester and polyurethane stretch fabric (trade name: silky dry, manufactured by Toray). Then, an electrode cloth in which the conductive polymer was fixed on the cloth with ethanol (Kanto Chemical) to impart conductivity was used.
A conductive mesh of 3 × 4 cm silver-plated nylon cloth (SparkFun, USA) was layered on the back of the electrode body, and a signal cable was joined to the conductive mesh. The electrode body was connected to the heart rate monitor via this signal cable.
A 4 × 5 cm polymer gel sheet (trade name: Sunwet, Sanyo Chemical Industries) that absorbs 2 cc of purified water Milli-Q water (trade name: Milli pore, manufactured by Merck Millipore) on the back of the conductive mesh. Manufactured) and a laminated body in which the electrode body, the conductive mesh, and the polymer gel sheet were laminated in this order was obtained. The purified water impregnated in the polymer gel sheet was soaked into the electrode body through the conductive mesh to wet the electrode body. Further, the outer side of the polymer gel sheet was covered (covered) with a moisture-permeable and waterproof membrane (waterproof membrane) (trade name: Entrant 2000, manufactured by Toray Industries, Inc.).
Prepare two body surface-mounted electrodes prepared as described above, and stretch the moisture-permeable waterproof membrane provided on each electrode with a band of stretch cloth (trade name: LYCRA, manufactured by Toyo Perontex). Covered. At this time, the two electrodes were sewn and fixed on the band so that the distance between the electrodes was 15 cm.
The produced band made of stretch cloth was wrapped around the front chest of an adult male and fixed so that the electrode body was in close contact with the skin.

[Comparative Example 1]
The heart rate was measured in the same manner as in Example 1 using an electrode of a commercially available heart rate monitor (manufactured by Polar) as the body surface-mounted electrode of the comparative example. The result is shown in the chart of FIG.
The electrode of Comparative Example 1 is different from the electrode of Example 1 in that it does not include the electrode body of Example 1, includes the conductive mesh as the electrode body of Comparative Example 1, and does not include the polymer gel. The electrode main body is not impregnated with the liquid for moisturizing.
As shown in the chart, the heart rate could be measured at the beginning of the measurement, but it became impossible to measure around 3 am (the time indicated by the arrow), and the recording of the heart rate was stopped. This is because the sweating of the wearer stopped at bedtime at night, and the gap between the electrode body 1 and the skin surface S was dried, and the skin impedance was increased.

[Example 2]
A body-surface-mounted electrode of the second embodiment was prepared, and the electrode was placed on the stratum corneum of the skin epidermis at the upper end of the subject's sternum, and the Holter electrocardiogram waveform was measured with CM5 (between the upper end of the induced sternum V5). The chart is shown in FIG. In the vertical waveform shown on the left side of FIG. 3, the horizontal axis indicates the heart rate (beats / minute), and the vertical axis indicates time (time). The horizontal waveform shown on the right side of FIG. 3 shows the compressed waveform of the electrocardiogram. Recording of heartbeat and electrocardiogram was performed using an electrocardiograph Pico303 (manufactured by Suzuken). As a result, as shown in FIG. 3, the electrocardiogram measurement for about 10 minutes could be stably performed.

  The body surface installation type electrode of Example 2 is impregnated with 1 ml of glycerol (manufactured by Wako Pure Chemical Industries) impregnated in the electrode body and the conductive mesh (conductive cloth), and does not include the polymer gel sheet. The configuration is the same as that of the first embodiment.

  The configurations and combinations thereof in the embodiments described above are examples, and the addition, omission, replacement, and other modifications of the configurations can be made without departing from the spirit of the present invention. Further, the present invention is not limited by each embodiment, and is limited only by the scope of the claims.

  The body surface-mounted electrode according to the present invention can be widely used as a bioelectrode that can be used continuously for a long time in a wide range of fields such as medical care, health promotion, information technology, and wearable computers.

DESCRIPTION OF SYMBOLS 1 ... Electrode main body, 2 ... Polymer gel, 3 ... Protective sheet, 4 ... Conductive mesh, 5 ... Electrode main body, S ... Skin surface (horny layer), 10A, 10B ... Body surface installation type electrode

Claims (3)

An electrode body having water permeability is provided,
The body surface-installed electrode , wherein the electrode body has a conductive polymer, and the electrode body is impregnated with an ionic liquid. A biological signal measuring method comprising: mounting the body surface-mounted electrode according to claim 1 on a skin surface of a living body, and measuring an electrical signal of the living body. A biological signal measuring device comprising the body surface-mounted electrode according to claim 1.

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