JP6151032B2 - Makeup set - Google Patents

Description

  The present invention relates to a set of cosmetic preparations with good absorption of active ingredients.

In recent years, many so-called sheet masks in which a non-woven fabric or the like is impregnated with a cosmetic material containing a moisturizing component have been sold because of its ease of use and superiority in terms of functionality.
This is because the sheet mask is widely used in order to keep the cosmetic for a certain amount of time on the skin and greatly enhance the moisture retention of the skin.
In order to obtain the main purpose moisturizing property, a moisturizing agent such as glycerin, diglycerin, dipropylene glycol, and trimethylglycine is blended, so that an aqueous solution cosmetic is used.
Under such circumstances, the oil-soluble active ingredient cannot take a sufficient blending ratio.
Of course, even if there is moisturizing as the main application, the effect required for cosmetics such as whitening action, anti-inflammatory, anti-wrinkle, etc., and the preparation for skin external use is also a certain time in the state coated on the skin in the case of a preparation such as a sheet mask. Since it exists, a highly effective preparation is expected. (Patent Document 1)
However, there is no problem in blending a water-soluble drug, but it is possible to blend an oil-soluble drug into an emulsified liquid composition, and it is possible to use it in a small amount. There were cases where the intended purpose was not achieved in terms of absorption. (Patent Document 2)

JP 06-048914 A JP-T-2005-535677

  The object of the present invention is to obtain a more effective preparation by combining not only the effectiveness of a water-soluble drug such as moisture retention but also the effectiveness of an oil-soluble drug.

As a result of intensive studies by the inventors, a cosmetic set of a sheet-like mask impregnated with an oily solution containing an oil-soluble active ingredient and an aqueous solution containing a water-soluble active ingredient and an acrylic acid / alkyl methacrylate copolymer The makeup method using a sheet-like mask impregnated with an aqueous solution containing an aqueous solution containing an active ingredient and an acrylic acid / alkyl methacrylate copolymer after applying an oily solution containing the active ingredient is very effective. I found out that
By this method, the following expected effects were obtained.
1. The oil-soluble active ingredient contained in the oil-based solution was also highly absorbed by the skin by using the mask together.
2. Even when a sheet-like mask impregnated with an aqueous solution containing a water-soluble active ingredient was applied after the oil-based solution was applied, the proportion of the water-soluble active ingredient absorbed into the skin did not decrease.
This will be specifically described below.
First, an oily solution containing an oil-soluble active ingredient will be described.
The oil-soluble active ingredient and the oil-based raw material (base) are not particularly limited, but the type and blending amount are selected according to the purpose. (Note that there is no distinction between an oil-soluble active ingredient and an oil-based raw material (base). Depending on the purpose of the preparation, it may be an oil-soluble active ingredient or an oil-based raw material (base), but at least one Add ingredients for absorption to the above skin)
In addition, water-soluble components including water can be blended in the oily solution, but the blending amount varies depending on the form of the oily solution, such as the type and the type of other blending raw materials, but is preferably 50% or less, 20 % Or less is more preferable.
As the dosage form, an arbitrary dosage form is selected from liquid, oily gel, W / O type or O / W / O type emulsion.

Examples of oil-soluble active ingredients, oil-based raw materials (bases), and water-soluble ingredients
Avocado oil, almond oil, fennel oil, egoma oil, olive oil, orange oil, orange rafa oil, sesame oil, cacao butter, chamomile oil, carrot oil, cucumber oil, beef tallow fatty acid, kukui nut oil, safflower oil, shea butter, liquid shea Fat, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil, turtle oil, mink oil, egg yolk oil, palm oil, palm kernel oil, owl, coconut oil, beef tallow, lard , Squalene, squalane, pristane or various fats and oils such as hydrogenated products (hardened oil, etc.) of these fats and oils.
Waxes such as beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lanolin, hard lanolin, candelilla wax, montan wax, shellac wax, rice wax;
Mineral oils such as liquid paraffin, petrolatum, paraffin, ozokelide, ceresin, and microcristan wax.
Fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, linoleic acid, linolenic acid, docosahexaenoic acid, eicosapentaenoic acid, 12-hydroxystearic acid, undecylenic acid, tall oil, and lanolin fatty acid.
Alcohols such as ethanol, isopyropanol, lauryl alcohol, cetanol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, phytosterol, phenoxyethanol, 2-hexyldecanol, isostearyl alcohol, 2-octyldodecanol.
Ethylene glycol, diethylene glycol, triethylene glycol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, polyethylene glycol, propylene glycol, polypropylene glycol, 1,3-butylene glycol, pentyl glycol, glycerin, Polyhydric alcohols such as pentaerythritol, threitol, arabitol, xylitol, galactitol, sorbitol, lactitol, and maltitol.

Isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyldodecyl myristate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, diethyl phthalate, phthalate Esters such as dibutyl acid, lanolin acetate, ethylene glycol monostearate, propylene glycol monostearate, propylene glycol dioleate.
Metal soaps such as aluminum stearate, magnesium stearate, zinc stearate, calcium stearate and zinc palmitate.
Gum arabic, guaiac fat, karaya gum, tragacanth gum, quince seed, agar, casein, lactose, fructose, sucrose or ester thereof, trehalose or derivative thereof, dextrin, gelatin, pectin, starch, carrageenan, carboxymethyl chitin or chitosan, ethylene oxide Hydroxyalkyl (C2 to C4) chitin or chitosan to which alkylene (C2 to C4) oxide is added, etc., low molecular chitin or chitosan, chitosan salt, sulfated chitin or chitosan, phosphorylated chitin or chitosan, alginic acid or a salt thereof, Hyaluronic acid or its salt, chondroitin sulfate or its salt, heparin, ethyl cellulose, methyl cellulose, carboxymethyl cellulose, carboxyethyl cellulose, carboxyethyl cellulose sodium, hyaluronan Droxyethyl cellulose, hydroxypropyl cellulose, nitrocellulose, crystalline cellulose, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, polyvinyl methacrylate, polyacrylate, polyalkylene oxide such as polyethylene oxide and polypropylene oxide, or a crosslinked polymer thereof, carboxy Gum, saccharides or water-soluble polymer compounds such as vinyl polymer and polyethyleneimine.
Alkyl carboxylate, alkyl sulfonate, alkyl sulfate ester salt, alkyl phosphate ester salt, alkyl amine salt, alkyl quaternary ammonium salt, carboxylic acid type amphoteric surfactant, sulfate ester type amphoteric surfactant, sulfonic acid type Amphoteric surfactant, phosphate ester type amphoteric surfactant, ether type nonionic surfactant, ether ester type nonionic surfactant, ester type nonionic surfactant, block polymer type nonionic surfactant, nitrogen-containing Anionic surfactants such as type nonionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants.

Retinol, retinal, dehydroretinal, carotene, lycopene, thiamine hydrochloride, thiamine sulfate, riboflavin, pyridoxine, cyanocobalamin, folic acid, nicotinic acids, pantothenic acids, biotins, choline, inositols, vitamin C or derivatives thereof, ergocalci Ferrol, cholecalciferol, dihydrotaxosterol, vitamin E or its derivatives, various vitamins such as ubiquinones or their derivatives.
Valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine, cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid, hydroxylysine, arginine, ornithine, histidine And various amino acids such as amino acid derivatives such as sulfate, phosphate, nitrate, citrate, or pyrrolidone carboxylic acid.

  Red buds, ground yellow, woody, gallbladder, monomedicine, ginkgo, oolong tea, fennel, turmeric, summer hay, Chen bark, Ezokogi, Akemiko, auren, white birch, giant crape myrtle, okra, ginseng or tochibaninjin (carrot), olive, oregano , Orange, chamomile or roman chamomile, cam come, guarana, magnolia, gorye, gooseberry, clara, cranberry, grapefruit, clove, kobushi, magnolia, mausoleum, sakura, hemp, sanchinin carrot, yam, yam, sandscon, Shikunshi, shiso shiso, shiso, peony, honeysuckle, horseradish, celery, cucumber, yellowtail, daisou, chimpanzee, chikutsujinjin, tengusa, mocha tea, ladybird, toxa, dokudami, tochu, ash, cinnamon, cinnamon Double, Neubara, Novara, Barley, Rose, Rhizome, Loquat, Blackberry, Prunes, Hornbill, Bowfish (Windbreak), Honoki, Bodaiju, Button, Hop, Jojoba, Maow, Maca, Macadamia nut, Mulberry bark, Bitter , Garlic mushroom, berry, milobaran, mugwort, purple, beetle grass, evening primrose, melissa, melirot, mokko, yacon, eucalyptus, saxifrage, yucca, yuzu, lily, licorice, mugwort, lavender, lemon, lemongrass, rosemary, earthenware, Various extracts of plants, seaweeds, and algae such as chlorella, chlorella, kombu, wakame, giant kelp, hijiki, hibamata, giraffe, asakusanori, susbinori, spirulina, shigege, iroro, fukuronori.

Horse or pig placenta extract, silk protein and its degradation products or their derivatives, milk, casein and its degradation products or their derivatives, skim milk powder and its degradation products or their derivatives, lactoferrin or its degradation products, egg component Animal-derived materials such as fish meat degradation products and nucleic acid-related substances (ribonucleic acid, deoxyribonucleic acid).
Marine products such as deep sea water, sea salt, dried sea water, dead sea or Atlantic or Pacific ocean, marine products such as sea mud.
Yeast extract, Bacteria metabolite, Bacteria extract, Mold or actinomycete metabolite, Mold or actinomycetes extract, Natto metabolite, Natto extract, Rice fermented extract, Rice bran (red rice cake, White rice) fermented extract, Fungi-derived substances such as lactic acid fermentation products of raw milk or skim milk powder, lactic acid bacteria fermentation products of legumes, and lactic acid bacteria fermentation products of coconut palm plants.
Α-hydroxy acids such as glycolic acid, citric acid, malic acid, tartaric acid and lactic acid.
Silica, magnesium silicate, talc, kaolin, bentonite, mica, mica titanium, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, calcium carbonate, magnesium carbonate, yellow iron oxide, red iron oxide, black iron oxide , Inorganic pigments such as Gunjo, chromium oxide, chromium hydroxide, carbon black, and calamine.
UV absorbers or blocking agents such as benzophenone derivatives, paraaminobenzoic acid derivatives, methoxycinnamic acid derivatives, salicylic acid derivatives, urocanic acid derivatives.

Paraaminobenzoic acid derivative, salicylic acid derivative, anthranilic acid derivative, coumarin derivative, amino acid compound, benzotriazole derivative, hydroquinone or derivative thereof, nicotinic acid derivative, kojic acid or derivative thereof, oxybenzone, benzophenone, arbutin, guaiazulene, shikonin, baicalin , Whitening agents such as baicalein, berberine, placenta extract, ellagic acid, lucinol.
Ictamol, indomethacin, kaolin, salicylic acid, sodium salicylate, methyl salicylate, acetylsalicylic acid, diphenhydramine hydrochloride, d-camphor, dl-camphor, hydrocortisone, guaiazulene, camazulene, chlorpheniramine maleate, glycyrrhizic acid or its salt, glycyrrhetinic acid or its Salt anti-inflammatory agent.
Antibacterial, bactericidal and antiseptics such as acrinol, sulfur, calcium gluconate, chlorhexidine gluconate and triclosan.
Musk, Civet, Castorium, Ambergris, Ylang Ylang Essential Oil, Iris Essential Oil, Fennel Essential Oil, Orange Essential Oil, Cardamom Essential Oil, Cinnamon Essential Oil, Geranium Essential Oil, Copaiba Balsam Essential Oil, Cedarwood Essential Oil, Jasmine Essential Oil, Rose Essential Oil, Bergamot Essential Oil, Lavender Essential Oil, Animal and vegetable fragrances such as lemongrass essential oil, lemon essential oil, rosemary essential oil, and other synthetic fragrances.
Photosensitive element 101, photosensitive element 201, photosensitive element 401, photosensitive element 301, hinokitiol, pantothenic acid or derivatives thereof, allantoin, pentadecanoic acid glyceride, urea, guanidine and other various drugs.
Other hormones, sequestering agents, pH adjusters and the like can be mentioned.
Of these, preferred as oil-soluble active ingredients are oils of vitamin C such as ascorbyl monostearate, ascorbyl monopalmitate, ascorbyl dipalmitate, ascorbyl triisopalmitate, ascorbyl tetraisopalmitate, ascorbyl tetrahexyldecanoate, etc. Examples include soluble derivatives, vitamin E such as tocopherol and tocophenol acetate, and derivatives thereof, vitamin A such as retinol, retinal, and retinol palmitate and derivatives thereof, ceramide or a similar substance, and stearyl glycyrrhetinate.

Next, a sheet-like mask impregnated with an aqueous solution containing a water-soluble active ingredient and an acrylic acid / alkyl methacrylate copolymer will be described.
The water-soluble active ingredient is selected according to the purpose of the preparation, but is not particularly limited as long as it is a water-soluble and effective substance listed above. Ascorbic acid and its derivatives, glycyrrhizinate, Degraded conchiolin and hydrolyzed collagen are preferred.
In addition to the above, the inventors have found that a water-soluble component is blended if necessary, but the effect is enhanced by blending an acrylic acid / alkyl methacrylate copolymer.
The acrylic acid / methacrylic acid copolymer is a copolymer of a structural unit derived from an acrylic acid monomer and a structural unit derived from an alkyl methacrylate monomer, and the structural ratio is preferably 1:99 to 99: 1, and the number of carbon atoms of the alkyl methacrylate monomer is preferably 10-30.
These acrylic acid / methacrylic acid copolymers include the following commercially available products, which are selected and used.
Pemulene TR-1, Pemulen TR-2, Carbopol R1342, Carbopol R1382, etc. The amount of this acrylic acid / methacrylic acid copolymer depends on the purpose of the preparation, the type of acrylic acid / methacrylic acid copolymer, and other compounds However, it is 0.01 to 10% by weight of the aqueous solution, more preferably 0.05 to 5% by weight, still more preferably 0.1 to 1% by weight. is there.
In addition, an aqueous solution is prepared by selecting raw materials as necessary.
As the dosage form of the aqueous solution, an arbitrary dosage form is selected from liquid, oily gel, O / W type, W / O / W type emulsion and the like.
Of course, oily raw materials can also be blended, but the blending amount varies depending on the type of the other blended raw materials and the like, but is preferably 10% or less, more preferably 3% or less.

The sheet is impregnated with the above aqueous solution.
The sheet was selected from water-absorbing non-woven fabric, woven fabric, paper, etc., using natural fibers such as cotton, silk, wool, polyester, rayon, polyolefin, polyethylene terephthalate, or synthetic fibers as required. A sheet material can be used.

  After applying an oil-based solution containing an oil-soluble active ingredient, a face mask coated with an aqueous solution containing a water-soluble active ingredient and an acrylic acid / alkyl methacrylate copolymer is coated on the face. The coating time is 3 to 100 minutes, preferably 5 to 30 minutes.

EXAMPLES Next, an Example is given and this invention is demonstrated in detail. (Values are shown in parts by weight.)
Oily solution-1
Ascorbyl tetra-2-hexyldecanoate 3.0
Liquid paraffin 30.0
Isopropyl myristate 33.0
Olive oil 33.9
BHT 0.1

Aqueous solution-1
Ascorbic acid 2-glucoside 2.0
Purified water 72.5
Glycerin 10.0
Acrylic acid / alkyl methacrylate copolymer (Pemulene TR-2) 0.25
Methyl paraoxybenzoate 0.25
This was adjusted to pH 6.7 with a 5% aqueous potassium hydroxide solution.

Sheet-1
(Nisshinbo Co., Ltd., trade name: 2ATEP2070)

Confirmation test-1
After collecting, Yucatan minipig skin (5-month-old female; Nippon Charles River) preserved at −80 ° C. was applied to pork skin (2 cm × 2 cm) thawed at room temperature, and 14 mg of oily solution-14 was applied onto the skin. 1 Place Sheet-1 containing 248 mg.
The pork skin was placed on a filter paper containing a phosphoric acid isotonic solution and allowed to stand at 32 ° C. for 1 hour.
As a control, 14 mg of oily solution-14 was applied to pig skin (2 cm × 2 cm) and left at 32 ° C. for 1 hour.
Thereafter, the sheet is removed (the control remains as it is), the surface of the pig skin is wiped with Kimwipe, and tape stripping is performed three times. Thereafter, the surface of the pig skin was heated at 60 ° C. for 45 seconds, and the epidermis (1.5 cm × 1.5 cm) was collected with tweezers. (Weighed the epidermis)
The collected epidermis was shaken and extracted (120 rpm) with 10 mL of 2-propanol for 19 hours. Place in HPLC mobile phase and perform shake extraction (120 rpm) for 4 hours. Ascorbyl tetra-2-hexyldecanoate in this extract was measured by HPLC under the following conditions.
-HPLC measurement condition column: Develosil ODS-P-5 4.6 mm x 150 mmL
Mobile phase: Methanol equipment Setting conditions: Detection wavelength 220 nm, flow rate 1 mL / min, column temperature 40 ° C
The weight of ascorbyl tetra-2-hexyldecanoate per gram of epidermis was calculated, and when the control was 1, the results of the examples are shown in FIG.

Confirmation test-2
After collecting, Yucatan minipig skin (5-month-old female; Nippon Charles River) preserved at −80 ° C. was applied to pork skin (2 cm × 2 cm) thawed at room temperature, and 14 mg of oily solution-14 was applied onto the skin. 1 Place Sheet-1 containing 248 mg.
The pork skin was placed on a filter paper containing a phosphoric acid isotonic solution and allowed to stand at 32 ° C. for 1 hour.
As a control, Sheet-1 containing 248 mg of aqueous solution-1 was directly placed on pork skin (2 cm × 2 cm) and left at 32 ° C. for 1 hour.
Thereafter, the sheet is removed, the surface of the pig skin is wiped off with Kimwipe, and tape stripping is performed three times. Thereafter, the surface of the pig skin was heated at 60 ° C. for 45 seconds, and the epidermis (1.5 cm × 1.5 cm) was collected with tweezers. (Weighed the epidermis)
The collected epidermis is put into a 5 mL HPLC mobile phase and shake-extracted (120 rpm) for 4 hours. Ascorbic acid 2-glucoside of this extract was measured by HPLC under the following conditions.

HPLC measurement condition column: Mightysil RP-18GP 4.6 mm × 250 mmL (5 μm)
Mobile phase: Tetrabutylammonium-potassium dihydrogen phosphate aqueous solution / acetonitrile (9: 1) mixed equipment setting conditions: flow rate 0.8 mL / min, detection wavelength 260 nm, column temperature 40 ° C.
When the weight of 2-glucosi ascorbic acid per gram of epidermis was calculated and the control was 1, the results of the examples are shown in FIG.

Confirmation test-3
After collecting, Yucatan minipig skin (5-month-old female; Nippon Charles River) preserved at −80 ° C. was applied to pork skin (2 cm × 2 cm) thawed at room temperature, and 14 mg of oily solution-14 was applied onto the skin. 1 Place Sheet-1 containing 248 mg.
A comparative aqueous solution-1 was used in place of the aqueous solution-1, and the others were tested for comparison. Then, the sheet was removed, the pig skin surface was wiped with a Kimwipe, and tape stripping was performed. Repeat three times. Thereafter, the surface of the pig skin was heated at 60 ° C. for 45 seconds, and the epidermis (1.5 cm × 1.5 cm) was collected with tweezers. (Weighed the epidermis)
The collected epidermis is put into a 5 mL HPLC mobile phase and shake-extracted (120 rpm) for 4 hours. Ascorbic acid 2-glucoside of this extract was measured by the method described in Confirmation Test-2.
The weight of ascorbic acid 2-glucoside per gram of epidermis is shown in FIG.

The comparative aqueous solution-1 was prepared by replacing the aqueous solution-1 with acrylic acid / alkyl methacrylate copolymer with the same amount of purified water and adjusting the pH to 6.7 with a 5% aqueous potassium hydroxide solution.

From Confirmation Test-1, ascorbyl tetra-2-hexyldecanoate blended with oily solution-1 is more applied when sheet-1 impregnated with aqueous solution-1 is further applied than simply applying oily solution-1. However, the percutaneous absorption of ascorbic acid 2-glucoside blended in aqueous solution-1 was not inhibited by applying oily solution-1. (Confirmation test-2)
In order to examine the effect of the acrylic acid / alkyl methacrylate copolymer blended in the aqueous solution-1 in such a preparation and coating method, a confirmation test-3 was conducted. As a result, blending of the acrylic acid / alkyl methacrylate copolymer was conducted. There was a significant difference with or without.

Oily solution-2
Ascorbyl tetra-2-hexyldecanoate 3.0
Bisabolol 0.5
Squalane 30.0
Beeswax 1.0
Tocopherol acetate 1.0
Retinol palmitate 1.0
Erythrityl triethylhexanoate 10.0
Ethyl hexyl palmitate 33.9
Isononyl isononanoate 19.5
Vitamin E 0.1

Aqueous solution-2
Ascorbic acid 2-glucoside 2.0
Dipotassium glycyrrhizinate 0.5
Hydrolyzed collagen 0.2
Purified water 71.5
Glycerin 10.0
1,3 Butylene glycol 5.0
Acrylic acid / alkyl methacrylate copolymer (Pemulene TR-1) 0.5
Methyl paraoxybenzoate 0.3
This was adjusted to pH 6.5 with 5% aqueous potassium hydroxide solution.

Sheet-1
(Nisshinbo Co., Ltd., trade name: 2ATEP2070)

Oily solution-3
Ceramide 2 0.1
Sugar Ceramide (from horse) 2.0
Beeswax 3.0
Squalane 15.0
Hydrogenated polyolefin (C6-12) 10.0
Spearmint oil 0.5
Tocopherol acetate 1.0
Retinol palmitate 1.0
Glyceryl tri-2-ethylhexanoate 10.0
Isononyl isononanoate 33.9
Erythrityl triethylhexanoate 10.0
Diisopropyl sebacate 3.4
Vitamin E 0.1

Aqueous solution-3
Ascorbic acid 2-glucoside 2.0
Dipotassium glycyrrhizinate 0.5
Hydrolyzed collagen 1.0
Hydrolyzed conchiolin 1.0
Hyaluronic acid Na 0.5
Purified water 72.6
Sorbitol 5.0
Dipropylene glycol 5.0
Acrylic acid / alkyl methacrylate copolymer (Pemulene TR-2) 0.1
Methyl paraoxybenzoate 0.3
This was adjusted to pH 6.5 with 5% aqueous potassium hydroxide solution.

Sheet-1
(Nisshinbo Co., Ltd., trade name: 2ATEP2070)

After applying the oily solution-1 and coating the face 1 impregnated with the aqueous solution-1 on the face for 10 minutes, the whitening effect was very high.
After applying the oily solution-2, the sheet-2 impregnated with the aqueous solution-2 was coated on the face for 20 minutes. As a result, the whitening effect and the effect of improving the rough skin were very high.
After applying the oily solution-3, the sheet 3 impregnated with the aqueous solution-3 was coated on the face for 30 minutes. As a result, the effect of improving the rough skin was very high, and the firmness of the skin was improved.
Of course, the improvement of the moist feeling of the skin was great.

The result of the confirmation test 1 is shown. The result of the confirmation test 2 is shown. The result of the confirmation test 3 is shown.

Claims (3)

  A cosmetic method using a sheet mask in which an oily solution containing an oil-soluble active ingredient is applied and then impregnated with an aqueous solution containing a water-soluble active ingredient and an acrylic acid / alkyl methacrylate copolymer.   The cosmetic method according to claim 1, wherein the oil-soluble active ingredient is at least one selected from vitamin A and derivatives thereof, vitamin E and derivatives thereof, oil-soluble derivatives of vitamin C, ceramide, and the like.   The cosmetic method according to claim 1 or 2, wherein the water-soluble active ingredient is at least one selected from ascorbic acid and derivatives thereof, glycyrrhizinate, hydrolyzed conchiolin, and hydrolyzed collagen.