JP6132851B2 - 一般的な抗炎症反応を与える複数のプロスタグランジン受容体において作用する化合物 - Google Patents

一般的な抗炎症反応を与える複数のプロスタグランジン受容体において作用する化合物 Download PDF

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JP6132851B2
JP6132851B2 JP2014548851A JP2014548851A JP6132851B2 JP 6132851 B2 JP6132851 B2 JP 6132851B2 JP 2014548851 A JP2014548851 A JP 2014548851A JP 2014548851 A JP2014548851 A JP 2014548851A JP 6132851 B2 JP6132851 B2 JP 6132851B2
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substituted
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alkoxy
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JP2015500883A (ja
JP2015500883A5 (enExample
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ユッシ ジェイ カンガスメトサ
ユッシ ジェイ カンガスメトサ
ウィリアム アール カーリング
ウィリアム アール カーリング
ホセ エル マルトス
ホセ エル マルトス
ジェニー ダブリュ ワン
ジェニー ダブリュ ワン
デイヴィッド エフ ウッドワード
デイヴィッド エフ ウッドワード
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Allergan Inc
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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
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JP2014548851A 2011-12-21 2012-12-19 一般的な抗炎症反応を与える複数のプロスタグランジン受容体において作用する化合物 Active JP6132851B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161578456P 2011-12-21 2011-12-21
US61/578,456 2011-12-21
PCT/US2012/070710 WO2013096501A1 (en) 2011-12-21 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response

Publications (3)

Publication Number Publication Date
JP2015500883A JP2015500883A (ja) 2015-01-08
JP2015500883A5 JP2015500883A5 (enExample) 2016-02-18
JP6132851B2 true JP6132851B2 (ja) 2017-05-24

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ID=47436296

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JP2014548851A Active JP6132851B2 (ja) 2011-12-21 2012-12-19 一般的な抗炎症反応を与える複数のプロスタグランジン受容体において作用する化合物

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Country Link
US (1) US8969589B2 (enExample)
EP (1) EP2794574B1 (enExample)
JP (1) JP6132851B2 (enExample)
AU (1) AU2012358983B2 (enExample)
CA (1) CA2860392C (enExample)
WO (1) WO2013096501A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106146400A (zh) * 2015-03-20 2016-11-23 四川大学 苄基-1h-吡唑、苄基-1h-吡咯衍生物及其制备方法和用途
US9827225B2 (en) 2016-01-25 2017-11-28 Jenivision Inc. Use of prostacyclin antagonists for treating ocular surface nociception
WO2017153231A1 (de) * 2016-03-09 2017-09-14 Bayer Pharma Aktiengesellschaft Substituierte n-cyclo-2-arylisochinolinon-4-carboxamide und ihre verwendung
WO2017153234A1 (de) * 2016-03-09 2017-09-14 Bayer Pharma Aktiengesellschaft Substituierte n-cyclo-2-arylchinolin-4-carboxamide und ihre verwendung
TW202228674A (zh) 2020-11-13 2022-08-01 日商小野藥品工業股份有限公司 藉由併用ｅｐ４拮抗藥與免疫檢查點抑制物質而進行之癌症治療
CN118184646A (zh) * 2024-05-14 2024-06-14 苏州弘道新材料有限公司 用于光伏胶膜的吡唑啉衍生物光转换材料及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
ES2298832T3 (es) * 2003-10-24 2008-05-16 Glaxo Group Limited Compuestos heterociclicos.
GB0508472D0 (en) * 2005-04-26 2005-06-01 Glaxo Group Ltd Compounds
US8492424B2 (en) * 2010-07-01 2013-07-23 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response

Also Published As

Publication number Publication date
EP2794574A1 (en) 2014-10-29
CA2860392A1 (en) 2013-06-27
US20130165665A1 (en) 2013-06-27
WO2013096501A1 (en) 2013-06-27
EP2794574B1 (en) 2017-11-08
AU2012358983B2 (en) 2017-09-14
CA2860392C (en) 2016-08-30
JP2015500883A (ja) 2015-01-08
AU2012358983A1 (en) 2014-07-17
US8969589B2 (en) 2015-03-03

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