JP6130142B2 - Topical skin preparation - Google Patents

Description

  The present invention relates to a leave-on skin external preparation for massage.

  For the purpose of blood circulation promotion effect and lift-up effect, beauty treatment by massage has been performed for a long time. In general, there are massage cosmetics mainly intended for a massage effect, and the dosage forms can be broadly classified into water bases and oil bases. For example, the oil-based base contains a large amount of oil, and the oil used is liquid to semi-solid, such as hydrocarbon oil such as squalane, triglyceride oil such as olive oil, and ester oil. Is known (for example, Patent Document 1). On the other hand, as an aqueous base, massage is possible by blending various water-soluble polymers, and aqueous gel type massage cosmetics are also used (for example, see Patent Document 2).

JP 2005-82481 A JP 2004-339110 A

With the technology of Patent Document 1, there is no freshness and there is a problem with the feeling of use, such as the weight of the feeling of use due to the oil contained in a large amount, the stickiness due to the oil remaining on the skin after massage, the feeling of glare and the feeling of obstruction remain. there were. On the other hand, the technique of Patent Document 2 that is a water-based massage cosmetic is a technique that uses a water-soluble polymer such as carboxyvinyl polymer having high versatility as an aqueous gel. Since it is necessary to blend the molecules at a high level, there is a problem that twisting occurs. In particular, in leave-on type massage cosmetics, these problems were felt remarkably, and improvements were required.
Accordingly, an object of the present invention is to provide a leave-on skin external preparation for massage that has good elongation on the skin, is easy to massage, does not become sticky, and does not cause twisting.

  Therefore, as a result of various studies to solve the above problems, the present inventor has combined a low-viscosity liquid ester oil, a linear higher alcohol, an N-acylamino acid salt, and an acrylamide-based water-soluble polymer. When blended, it is easy to massage on the skin, is not sticky, does not cause glare and kinks, has excellent moisturizing and penetrating feeling, and can be applied after application. The present invention was completed by finding that an agent can be obtained.

That is, this invention provides the leave on skin external preparation for massage characterized by containing the following component (A)-(D).
(A) Liquid ester oil having a viscosity at 25 ° C. of 25 mPa · s or less (B) Linear higher alcohol (C) N-acylamino acid or salt thereof (D) 2-acrylamido-2-methylpropanesulfonic acid or salt thereof , And a homopolymer, copolymer, or crosspolymer containing one or more selected from acrylamide as a structural unit

  The leave-on skin external preparation for massage of the present invention is excellent in stability, stretches well on the skin, is easy to massage, does not become sticky, does not cause glare or twist, and has excellent moisturizing feeling and penetration feeling. is there. Furthermore, after applying the leave-on skin external preparation for massage of the present invention, makeup can be performed immediately, and the effect of improving the makeup paste of the makeup cosmetic can be obtained.

  (A) The liquid ester oil having a viscosity of 25 mPa · s or less at 25 ° C. used in the present invention is a low-viscosity liquid ester oil, which is easy to massage, easy to massage and non-sticky. is there.

As the component (A), an ester of a fatty acid having 6 to 24 carbon atoms and a monohydric alcohol having 2 to 24 carbon atoms, 2 having 2 to 4 carbon atoms such as a fatty acid having 6 to 24 carbon atoms, propylene glycol, propanediol and the like. Mono- or di-ester with a monohydric alcohol, diester of a dibasic fatty acid having 4 to 10 carbon atoms with a monohydric alcohol with 2 to 8 carbon atoms, diester with carbonic acid and a monohydric alcohol with 6 to 18 carbon atoms, etc. It is done.
Among these, esters of fatty acids having 8 to 10 carbon atoms and monohydric alcohols having 2 to 24 carbon atoms, diesters of carbonic acid and monohydric alcohols having 6 to 18 carbon atoms, fatty acids having 8 to 10 carbon atoms and carbon numbers 2 Diesters with -4 dihydric alcohols, diesters with dibasic fatty acids having 8 to 10 carbon atoms and monohydric alcohols having 2 to 4 carbon atoms are more preferred. Here, the fatty acid and alcohol may be linear or branched.

  Specific examples of the component (A) include isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl oleate, ethyl linoleate, isopropyl linoleate, cetyl caprylate, hexyl laurate, decyl myristate, decyl oleate Oleyl oleate, isotridecyl isononanoate, isocetyl myristate, isocetyl palmitate, ethylhexyl palmitate, propylene glycol dioleate, isopropyl isostearate, cetyl 2-ethylhexanoate, di (caprylic acid / capric acid) propanediol, dicapric acid Propylene glycol, propylene glycol dioleate, isononyl isononanoate, diisopropyl sebacate, propylene glycol isostearate, dica carbonate Ririru, etc. can be mentioned. These can be used alone or in combination of two or more.

  In the present invention, it is preferable that the component (A) is an ester oil having a viscosity at 25 ° C. of 15 mPa · s or less from the viewpoint of suppressing the stickiness in the external preparation for skin and improving the feeling of use during massage. More preferably, it is 3 mPa · s or more and 15 mPa · s or less. The viscosity can be measured with a B-type viscometer (Bismetron viscometer: model VS-A1 (manufactured by Shibaura System); rotor No. 1, 60 revolutions / minute, 30 seconds) at 25 ° C. under 1 atm. .

  Among the component (A), as ester oil having a viscosity of 15 mPa · s or less, for example, isononyl isononanoate, diisopropyl sebacate, di (caprylic / capric) propanediol, cetyl 2-ethylhexanoate, dicaprylyl carbonate, etc. Preferably mentioned. These are used alone or in combination of two or more.

  (A) component used by this invention is a well-known substance, for example, it can manufacture easily by esterification of caprylic acid / capric acid and propanediol. Moreover, generally also commercially available, as di (caprylic acid / capric acid) propanediol, Saracos PR-85 sold by Nisshin Oilio Group Co., Ltd. can be mentioned.

  The content of the component (A) with respect to the total amount of the external preparation for skin is preferably 1% by mass or more, more preferably 3% by mass or more from the viewpoint of suppressing stickiness and being massageable and capable of makeup thereafter. 5 mass% or more is more preferable, 20 mass% or less is preferable, 18 mass% or less is more preferable, and also 16 mass% or less is preferable. Specifically, 1-20 mass% is preferable, 3-18 mass% is more preferable, and 5-16 mass% is further more preferable.

The (B) linear higher alcohol used in the present invention is not particularly limited as long as it is used for an external preparation for skin. ROH (R is a linear alkyl or alkenyl group having 12 or more carbon atoms) A straight-chain alcohol having 12 or more carbon atoms represented by) is preferably used. The higher alcohol is more preferably a saturated linear alcohol having 12 to 24 carbon atoms from the viewpoint of improving the stability of the emulsion preparation, the appearance of the emulsion preparation, the viscosity and the spreadability at the time of application, the softening of the skin, and the moisturizing effect. A saturated linear alcohol having 14 to 24 carbon atoms is more preferable, and a saturated linear alcohol having 16 to 22 carbon atoms is more preferable. Specific examples include myristyl alcohol, cetyl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol, carnervir alcohol, and the like, and one or more can be used in appropriate combination.
Of these, behenyl alcohol, stearyl alcohol, and cetostearyl alcohol are preferable.

  The content of the component (B) with respect to the total amount of the external preparation for skin is preferably 0.1% by mass or more, preferably 0.3% by mass or more from the viewpoint of suppressing stickiness and being massageable and capable of making up thereafter. Is more preferable, 0.5 mass% or more is further preferable, 8 mass% or less is preferable, 6 mass% or less is more preferable, and further 4 mass% or less is preferable. Specifically, 0.1-8 mass% is preferable, 0.3-6 mass% is more preferable, and 0.5-4 mass% is further more preferable.

  The (C) N-acylamino acid or salt thereof used in the present invention is a water-soluble surfactant. Examples of amino acids constituting the N-acyl amino acid include glutamic acid, aspartic acid, glycine, alanine, threonine, methylalanine, sarcosine, lysine, arginine and the like. These amino acids may be L-form, D-form or DL-form. One of these may be used, or two or more selected from the above group may be mixed and used. From the viewpoints of dispersion stability and no stickiness, acidic amino acids or neutral amino acids are more preferred. Specifically, glutamic acid, aspartic acid, glycine, and alanine are more preferable, and glutamic acid is particularly preferable. Examples of N-acyl amino acid salts include alkali metal salts such as sodium salts and potassium salts, and amine salts such as ammonium salts and ethanolamine salts.

  The content of the component (C) with respect to the total amount of the external preparation for skin is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, from the viewpoint of suppressing stickiness and maintaining stability. % By mass or more is more preferable, 2% by mass or less is preferable, 1.8% by mass or less is more preferable, and 1.6% by mass or less is more preferable. Specifically, 0.1 to 2 mass% is preferable, 0.3 to 1.8 mass% is more preferable, and 0.5 to 1.6 mass% is more preferable.

The homopolymer, copolymer, or crosspolymer containing (D) 2-acrylamido-2-methylpropanesulfonic acid and acrylamide selected from (D) as a constituent unit in the present invention is not particularly limited. . Specifically, vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, dimethylacrylamide / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, acrylamide / 2-acrylamide- 2-methylpropanesulfonic acid copolymer, dimethylacrylamide / 2-acrylamide-2-methylpropanesulfonic acid cross-polymer cross-linked with methylenebisacrylamide, mixture of polyacrylamide and sodium polyacrylate, sodium acrylate / 2 Acrylamide-2-methylpropanesulfonic acid copolymer, hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, polyacrylamide / ammonium acrylate copolymer Acrylamide / sodium acrylate copolymer and the like. However, it is not limited to these examples.
In the above, as the salt, alkali metal salt (for example, calcium salt, magnesium salt, etc.), ammonium salt, organic amine salt (for example, monoethanolamine salt, diethanolamine salt, triethanolamine salt, triethanolamine salt, etc.) And the like. 1 type, or 2 or more types can be used for these (D) components.

  These components (D) may be synthesized or commercially available. For example, as vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, “ARITOFLEX AVC” (manufactured by Clariant), sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid (salt) ) As the copolymer, “SIMULGEL EG” (manufactured by SPPIC), “SIMULGEL EPG” (manufactured by SPPIC), and acrylamide / 2-acrylamido-2-methylpropanesulfonic acid sodium salt copolymer as “SIMULGEL 600” ”(Made by SEPPIC), acrylamide / 2-acrylamido-2-methylpropanesulfonic acid (salt),“ SEPIGEL 305 ”(made by SPPIC),“ SEPIGEL 501 ”(made by SPPIC), 2-acrylic Examples of homopolymers of amido-2-methylpropanesulfonic acid sodium salt include “Hostacerin AMPS” (manufactured by Clariant), “SIMULGEL 800” (manufactured by SPPIC), and the like. Dimethylacrylamide / 2-acrylamido-2-methyl Examples of propanesulfonic acid include “SU-POLYMER G-1” (manufactured by Toho Chemical Co., Ltd.).

  The content of the component (D) with respect to the total amount of the external preparation for skin is preferably 0.1% by mass or more from the viewpoint of suppressing stickiness, causing no twisting at the time of makeup, and maintaining stability. It is more preferably at least mass%, more preferably at least 0.3 mass%, more preferably at most 2.5 mass%, more preferably at most 2.0 mass%, further preferably at most 1.5 mass%. Specifically, 0.1 to 2.5 mass% is preferable, 0.2 to 2.0 mass% is more preferable, and 0.3 to 1.5 mass% is more preferable.

  The dosage form of the external preparation for skin of the present invention is not particularly limited, but can be applied to creams, emulsions, cosmetics, sunscreens, and the like, and can also be applied as sprays and mousses.

  The external preparation for skin of the present invention is preferably an emulsified composition, and the emulsified type can be applied to various emulsified types without limitation of water-in-oil emulsification, oil-in-water emulsification, etc., but suppresses stickiness. An oil-in-water emulsion composition that is easy to make up is preferable.

  The external preparation for skin of the present invention is, in addition to the essential components described above, other optional components that are usually used in pharmaceuticals, quasi-drugs, cosmetics and the like as long as the effects of the present invention are not impaired as necessary. For example, anionic surfactants other than component (C), cationic surfactants, nonionic surfactants, oils other than component (A), ultraviolet absorbers, preservatives, humectants, component (D) Other components such as polymers, amino acid derivatives, sugar derivatives, fragrances, water, alcohols, thickeners, colorants, sequestering agents, antioxidants, and drugs can be appropriately blended.

  The external preparation for skin of the present invention is an external preparation for massage used by applying to the skin of the face, hands, feet, etc. and massaging. In addition, it is a leave-on type skin external preparation that does not need to be washed away after the massage is completed. It is also possible to make up after massage using the external preparation for skin of the present invention.

  In relation to the above-described embodiment, the present invention further discloses the following embodiment.

<1> A leave-on skin external preparation for massage, comprising the following components (A) to (D).
(A) Liquid ester oil having a viscosity at 25 ° C. of 25 mPa · s or less (B) Linear higher alcohol (C) N-acylamino acid or salt thereof (D) 2-acrylamido-2-methylpropanesulfonic acid or salt thereof , And a homopolymer, copolymer, or crosspolymer containing one or more selected from acrylamide as a structural unit

<2> The component (A) is an ester of a fatty acid having 6 to 24 carbon atoms and a monohydric alcohol having 2 to 24 carbon atoms, a fatty acid having 6 to 24 carbon atoms, propylene glycol, propanediol, etc. Mono- or di-ester with dihydric alcohol, diester with dibasic fatty acid having 4 to 10 carbon atoms and monohydric alcohol with 2 to 8 carbon atoms, and diester with carbonic acid and monohydric alcohol with 6 to 18 carbon atoms The skin external preparation of <1> which is one or more selected.
<3> Component (A) is an ester of a fatty acid having 8 to 10 carbon atoms and a monohydric alcohol having 2 to 24 carbon atoms, a diester of carbonic acid and a monohydric alcohol having 6 to 18 carbon atoms, or 8 to 10 carbon atoms. It is 1 type, or 2 or more types chosen from the diester of a C2-C4 dihydric alcohol, and the diester of a C8-C10 dibasic fatty acid and a C2-C4 monohydric alcohol <1> or <2> skin external preparation.
The skin external preparation in any one of <1>-<3> whose <4> (A) component is ester oil whose viscosity in 25 degreeC is 15 mPa * s or less.
<5> The content of the component (A) with respect to the total amount of the external preparation for skin is preferably 1% by mass or more, more preferably 3% by mass or more, further preferably 5% by mass or more, and preferably 20% by mass or less. More preferably, it is 18 mass% or less, More preferably, it is 16 mass% or less The skin external preparation in any one of <1>-<4>.
The content of the <6> component (A) with respect to the total amount of the external preparation for skin is preferably 1 to 20% by mass, more preferably 3 to 18% by mass, and further preferably 5 to 16% by mass. > Any one of the external preparations for skin.
<7> Component (B) is preferably a linear alcohol having 12 or more carbon atoms, more preferably a saturated linear alcohol having 12 to 24 carbon atoms, still more preferably a saturated linear alcohol having 14 to 24 carbon atoms, Preferably, it is a saturated linear alcohol having 16 to 22 carbon atoms, more preferably one or more selected from myristyl alcohol, cetyl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol and carnervir alcohol < The skin external preparation in any one of 1>-<6>.
<8> The content of the component (B) with respect to the total amount of the external preparation for skin is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, and further preferably 0.5% by mass or more. Is 8% by mass or less, more preferably 6% by mass or less, and still more preferably 4% by mass or less, according to any one of <1> to <7>.
<9> The content of the component (B) with respect to the total amount of the external preparation for skin is preferably 0.1 to 8% by mass, more preferably 0.3 to 6% by mass, and further preferably 0.5 to 4% by mass. The skin external preparation in any one of <1>-<8>.
<10> The amino acid constituting the N-acylamino acid of component (C) is one or more selected from glutamic acid, aspartic acid, glycine, alanine, threonine, methylalanine, sarcosine, lysine and arginine <1 The skin external preparation according to any one of> to <9>.
<11> The content of the component (C) with respect to the total amount of the external preparation for skin is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, further preferably 0.5% by mass or more, and preferably Is 2% by mass or less, more preferably 1.8% by mass or less, and still more preferably 1.6% by mass or less, according to any one of <1> to <10>.
<12> The content of the component (C) with respect to the total amount of the external preparation for skin is preferably 0.1 to 2% by mass, more preferably 0.3 to 1.8% by mass, and further preferably 0.5 to 1.6%. The skin external preparation according to any one of <1> to <11>, which is% by mass.
<13> (D) component is vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, dimethylacrylamide / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, acrylamide / 2-acrylamido-2-methylpropanesulfonic acid copolymer, dimethylacrylamide / 2-acrylamido-2-methylpropanesulfonic acid cross-polymer cross-linked with methylenebisacrylamide, a mixture of polyacrylamide and sodium polyacrylate, Sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, polyacrylamide / ammonium acrylate One or two or more types selected from a copolymer and an acrylamide / sodium acrylate copolymer, more preferably a vinylpyrrolidone / 2-acrylamide-2-methylpropanesulfonic acid (salt) copolymer, dimethylacrylamide / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, acrylamide / acrylic acid / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, polyacrylamide and polyacrylic acid (salt) Mixture, sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, acrylamide / acrylic acid (salt) copolymer, homopolymer of 2-acrylamido-2-methylpropanesulfonic acid (salt) And vinylformamide / 2-acrylamide-2-methyl The skin external preparation according to any one of <1> to <12>, which is one or more selected from a rupropanesulfonic acid (salt) copolymer.
<14> The content of the component (D) with respect to the total amount of the external preparation for skin is preferably 0.1% by mass or more, more preferably 0.2% by mass or more, and still more preferably 0.3% by mass or more. Is 2.5% by mass or less, more preferably 2.0% by mass or less, and still more preferably 1.5% by mass or less, according to any one of <1> to <13>.
<15> The content of the component (D) with respect to the total amount of the external preparation for skin is preferably 0.1 to 2.5% by mass, more preferably 0.2 to 2.0% by mass, and further preferably 0.3 to 1%. The external preparation for skin according to any one of <1> to <14>, which is 5% by mass.
<16> The external preparation for skin according to any one of <1> to <15>, which is an oil-in-water emulsion composition.

  Hereinafter, it demonstrates in detail by an Example and a comparative example. In addition, the unit of a composition is all the mass%.

  Prior to the examples, (1) storage stability test and (2) sensory evaluation test performed in the examples will be described.

(Storage stability test)
The sample was placed in a glass bottle, and the state and appearance after being left at 45 ° C. for 3 months were observed. When an abnormality was observed (separation, precipitation, etc.), x was indicated, and when no abnormality was observed, it was indicated by ○.

(Sensory evaluation test)
Using the emulsified composition for skin shown in the examples for 10 professional female panels, "Easy to massage", "Moisturizing feeling", "Sticky", "Skin feel (glitter, twist) The questionnaire was conducted on the five items, and the evaluation was performed based on the following evaluation criteria. A result is shown by the average score of the evaluation.

(Evaluation criteria)
Ease of massage 5: Good 4: Slightly good 3: Not good 2: Slightly bad 1: Bad

Moisturizing sensation 5: Good 4: Slightly good 3: Neither can be said 2: Slightly bad 1: Bad

No stickiness 5: None 4: Slightly absent 3: Neither can be said 2: Slightly present 1: Present

Feeling of remaining skin (glare, twist)
5: None 4: Slightly absent 3: Neither can be said 2: Slightly present 1: Present

Examples 1-8, Comparative Examples 1-6
Skin emulsified compositions having the compositions described in Tables 1 and 2 were prepared by a conventional method, and the above test was performed. The results are shown in Table 1 and Table 2 together.

As is clear from Tables 1 and 2, the leave-on emulsified composition for massage containing the components (A) to (D) of the present invention is stable for a long period of time, has good elongation on the skin, and is easy to massage. It had excellent moisturizing feeling, no stickiness, and no feeling of skin residue (roughness, twisting). Further, even if makeup was applied after application, the cosmetic paste was good.
On the other hand, when (A) component is not blended or liquid oil that does not correspond to (A) component is blended (Comparative Examples 1 to 3), such as ease of massage, moisturizing feeling, non-stickiness, feeling of remaining skin, etc. It was inferior in respect. Moreover, when (B) component, (C) component, or (D) component was not mix | blended (Comparative Examples 4-6), storage stability was bad and usability evaluation was also not enough.

  Next, Table 3 and Table 4 show formulation examples of the emulsion composition for skin of the present invention.

  An emulsified composition for skin (beauty liquid) having the above composition was prepared by a conventional method, and was excellent in all aspects of storage stability, moisturizing feeling, spread, non-stickiness, and creaking.

  An emulsion composition for skin (cream) having the above composition is prepared by a conventional method, and is excellent in storage stability, moisturizing feeling, ease of massage, non-stickiness and good feeling of skin residue (glare, twist) It was also excellent in terms of

Claims (3)

A leave-on skin external preparation for massage comprising the following components (A) to (D).
(A) a diester of carbonic acid and a monohydric alcohol having 6 to 18 carbon atoms, a diester of a fatty acid having 8 to 10 carbon atoms and a dihydric alcohol having 2 to 4 carbon atoms, and a dibasic fatty acid having 8 to 10 carbon atoms Liquid ester oil having a viscosity at 25 ° C. of 15 mPa · s or less, including one or more selected from diesters with monohydric alcohols having 2 to 4 carbon atoms : 5 to 16% by mass
(B) Linear higher alcohol : 1.5 to 4% by mass
(C) N-acyl amino acid or salt thereof in which the constituent amino acid is one or more selected from glutamic acid, aspartic acid, glycine, alanine, threonine, methylalanine, sarcosine, lysine and arginine : 0.1 to 2 mass %
(D) Homopolymer, copolymer, or crosspolymer containing one or more selected from 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof and acrylamide as a structural unit : 0.2 to 2.0 mass %   The skin external preparation according to claim 1, wherein the component (A) is a liquid ester oil having a viscosity at 25 ° C of 3 mPa · s to 15 mPa · s. Component (D) is vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, dimethylacrylamide / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, acrylamide / acrylic acid / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer, mixture of polyacrylamide and polyacrylic acid (salt), sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer , Acrylamide / acrylic acid (salt) copolymer, homopolymer of 2-acrylamido-2-methylpropanesulfonic acid (salt) and vinylformamide / 2-acrylamido-2-methylpropanesulfonic acid (salt) copolymer it is is one or more of claim 1 or 2 Hadagaiyo agent.