JP6093761B2 - 関連した組織サンプルの光学的分析に対する装置 - Google Patents
関連した組織サンプルの光学的分析に対する装置 Download PDFInfo
- Publication number
- JP6093761B2 JP6093761B2 JP2014518003A JP2014518003A JP6093761B2 JP 6093761 B2 JP6093761 B2 JP 6093761B2 JP 2014518003 A JP2014518003 A JP 2014518003A JP 2014518003 A JP2014518003 A JP 2014518003A JP 6093761 B2 JP6093761 B2 JP 6093761B2
- Authority
- JP
- Japan
- Prior art keywords
- emitting element
- light emitting
- data
- light
- tissue sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000003287 optical effect Effects 0.000 title claims description 57
- 238000004458 analytical method Methods 0.000 title claims description 16
- 238000002189 fluorescence spectrum Methods 0.000 claims description 45
- 238000001228 spectrum Methods 0.000 claims description 43
- 238000010521 absorption reaction Methods 0.000 claims description 36
- 238000005259 measurement Methods 0.000 claims description 32
- 238000000034 method Methods 0.000 claims description 29
- 238000012937 correction Methods 0.000 claims description 19
- 238000000862 absorption spectrum Methods 0.000 claims description 6
- 230000001419 dependent effect Effects 0.000 claims description 6
- 238000000411 transmission spectrum Methods 0.000 claims description 4
- 239000000523 sample Substances 0.000 description 67
- 239000000835 fiber Substances 0.000 description 35
- 230000005284 excitation Effects 0.000 description 14
- 230000008901 benefit Effects 0.000 description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 238000004422 calculation algorithm Methods 0.000 description 9
- 150000002632 lipids Chemical class 0.000 description 9
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 210000000481 breast Anatomy 0.000 description 6
- 239000013307 optical fiber Substances 0.000 description 6
- 238000001055 reflectance spectroscopy Methods 0.000 description 6
- 102000001554 Hemoglobins Human genes 0.000 description 5
- 108010054147 Hemoglobins Proteins 0.000 description 5
- 238000004364 calculation method Methods 0.000 description 5
- 238000001506 fluorescence spectroscopy Methods 0.000 description 5
- 230000003993 interaction Effects 0.000 description 5
- 238000013178 mathematical model Methods 0.000 description 5
- 102000008186 Collagen Human genes 0.000 description 4
- 108010035532 Collagen Proteins 0.000 description 4
- 229920001436 collagen Polymers 0.000 description 4
- 238000004590 computer program Methods 0.000 description 4
- 230000003595 spectral effect Effects 0.000 description 4
- 102000016942 Elastin Human genes 0.000 description 3
- 108010014258 Elastin Proteins 0.000 description 3
- 238000002679 ablation Methods 0.000 description 3
- 238000001574 biopsy Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 229920002549 elastin Polymers 0.000 description 3
- 238000000513 principal component analysis Methods 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 238000000342 Monte Carlo simulation Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000004611 spectroscopical analysis Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000005670 electromagnetic radiation Effects 0.000 description 1
- 238000000295 emission spectrum Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 238000007620 mathematical function Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 235000013622 meat product Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000000491 multivariate analysis Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 238000000985 reflectance spectrum Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11171666 | 2011-06-28 | ||
| EP11171666.8 | 2011-06-28 | ||
| PCT/IB2012/053133 WO2013001423A1 (en) | 2011-06-28 | 2012-06-21 | An apparatus for optical analysis of an associated tissue sample |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014518390A JP2014518390A (ja) | 2014-07-28 |
| JP2014518390A5 JP2014518390A5 (enExample) | 2015-07-09 |
| JP6093761B2 true JP6093761B2 (ja) | 2017-03-08 |
Family
ID=46582029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014518003A Expired - Fee Related JP6093761B2 (ja) | 2011-06-28 | 2012-06-21 | 関連した組織サンプルの光学的分析に対する装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140117256A1 (enExample) |
| EP (1) | EP2725967B1 (enExample) |
| JP (1) | JP6093761B2 (enExample) |
| CN (1) | CN103635131B (enExample) |
| BR (1) | BR112013033226A2 (enExample) |
| WO (1) | WO2013001423A1 (enExample) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11871901B2 (en) | 2012-05-20 | 2024-01-16 | Cilag Gmbh International | Method for situational awareness for surgical network or surgical network connected device capable of adjusting function based on a sensed situation or usage |
| US10881459B2 (en) | 2012-07-18 | 2021-01-05 | Bernard Boon Chye Lim | Apparatus and method for assessing tissue treatment |
| US10499984B2 (en) | 2012-07-18 | 2019-12-10 | Bernard Boon Chye Lim | Apparatus and method for assessing tissue treatment |
| JP2014171511A (ja) * | 2013-03-06 | 2014-09-22 | Olympus Corp | 被検体観察システム及びその方法 |
| WO2015140056A1 (en) | 2014-03-18 | 2015-09-24 | Koninklijke Philips N.V. | Tunable filters for spectral sensing |
| WO2016166067A1 (en) | 2015-04-17 | 2016-10-20 | Koninklijke Philips N.V. | Detection of anisotropic biological tissue |
| EP3141181B1 (en) * | 2015-09-11 | 2018-06-20 | Bernard Boon Chye Lim | Ablation catheter apparatus with a basket comprising electrodes, an optical emitting element and an optical receiving element |
| CA3043889A1 (en) * | 2016-11-17 | 2018-05-24 | Medici Technologies, LLC | Methods and apparatuses for central venous pressure measurement status |
| CN110892246A (zh) * | 2017-05-16 | 2020-03-17 | Meq普罗布有限公司 | 用于评估肉制品的质量的方法和系统 |
| US10842381B2 (en) | 2017-10-10 | 2020-11-24 | Colgate-Palmolive Company | Spectroscopic system and method therefor |
| US11801098B2 (en) | 2017-10-30 | 2023-10-31 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
| US11911045B2 (en) | 2017-10-30 | 2024-02-27 | Cllag GmbH International | Method for operating a powered articulating multi-clip applier |
| US11759224B2 (en) | 2017-10-30 | 2023-09-19 | Cilag Gmbh International | Surgical instrument systems comprising handle arrangements |
| US11564756B2 (en) | 2017-10-30 | 2023-01-31 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
| US11291510B2 (en) | 2017-10-30 | 2022-04-05 | Cilag Gmbh International | Method of hub communication with surgical instrument systems |
| US11510741B2 (en) | 2017-10-30 | 2022-11-29 | Cilag Gmbh International | Method for producing a surgical instrument comprising a smart electrical system |
| US10758310B2 (en) | 2017-12-28 | 2020-09-01 | Ethicon Llc | Wireless pairing of a surgical device with another device within a sterile surgical field based on the usage and situational awareness of devices |
| US11969142B2 (en) | 2017-12-28 | 2024-04-30 | Cilag Gmbh International | Method of compressing tissue within a stapling device and simultaneously displaying the location of the tissue within the jaws |
| US11376002B2 (en) | 2017-12-28 | 2022-07-05 | Cilag Gmbh International | Surgical instrument cartridge sensor assemblies |
| US11109866B2 (en) | 2017-12-28 | 2021-09-07 | Cilag Gmbh International | Method for circular stapler control algorithm adjustment based on situational awareness |
| US11324557B2 (en) | 2017-12-28 | 2022-05-10 | Cilag Gmbh International | Surgical instrument with a sensing array |
| US11857152B2 (en) | 2017-12-28 | 2024-01-02 | Cilag Gmbh International | Surgical hub spatial awareness to determine devices in operating theater |
| US11666331B2 (en) | 2017-12-28 | 2023-06-06 | Cilag Gmbh International | Systems for detecting proximity of surgical end effector to cancerous tissue |
| US11576677B2 (en) | 2017-12-28 | 2023-02-14 | Cilag Gmbh International | Method of hub communication, processing, display, and cloud analytics |
| US10595887B2 (en) | 2017-12-28 | 2020-03-24 | Ethicon Llc | Systems for adjusting end effector parameters based on perioperative information |
| US11998193B2 (en) | 2017-12-28 | 2024-06-04 | Cilag Gmbh International | Method for usage of the shroud as an aspect of sensing or controlling a powered surgical device, and a control algorithm to adjust its default operation |
| US20190201039A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Situational awareness of electrosurgical systems |
| WO2019133143A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Surgical hub and modular device response adjustment based on situational awareness |
| US11786251B2 (en) | 2017-12-28 | 2023-10-17 | Cilag Gmbh International | Method for adaptive control schemes for surgical network control and interaction |
| US20190201113A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Controls for robot-assisted surgical platforms |
| US12096916B2 (en) | 2017-12-28 | 2024-09-24 | Cilag Gmbh International | Method of sensing particulate from smoke evacuated from a patient, adjusting the pump speed based on the sensed information, and communicating the functional parameters of the system to the hub |
| US11832899B2 (en) | 2017-12-28 | 2023-12-05 | Cilag Gmbh International | Surgical systems with autonomously adjustable control programs |
| US11213359B2 (en) | 2017-12-28 | 2022-01-04 | Cilag Gmbh International | Controllers for robot-assisted surgical platforms |
| US11659023B2 (en) | 2017-12-28 | 2023-05-23 | Cilag Gmbh International | Method of hub communication |
| US11257589B2 (en) | 2017-12-28 | 2022-02-22 | Cilag Gmbh International | Real-time analysis of comprehensive cost of all instrumentation used in surgery utilizing data fluidity to track instruments through stocking and in-house processes |
| US10918310B2 (en) | 2018-01-03 | 2021-02-16 | Biosense Webster (Israel) Ltd. | Fast anatomical mapping (FAM) using volume filling |
| US11589888B2 (en) | 2017-12-28 | 2023-02-28 | Cilag Gmbh International | Method for controlling smart energy devices |
| US11896322B2 (en) | 2017-12-28 | 2024-02-13 | Cilag Gmbh International | Sensing the patient position and contact utilizing the mono-polar return pad electrode to provide situational awareness to the hub |
| US12376855B2 (en) | 2017-12-28 | 2025-08-05 | Cilag Gmbh International | Safety systems for smart powered surgical stapling |
| US12127729B2 (en) | 2017-12-28 | 2024-10-29 | Cilag Gmbh International | Method for smoke evacuation for surgical hub |
| US20190201090A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Capacitive coupled return path pad with separable array elements |
| US11464559B2 (en) | 2017-12-28 | 2022-10-11 | Cilag Gmbh International | Estimating state of ultrasonic end effector and control system therefor |
| US11678881B2 (en) | 2017-12-28 | 2023-06-20 | Cilag Gmbh International | Spatial awareness of surgical hubs in operating rooms |
| US11744604B2 (en) | 2017-12-28 | 2023-09-05 | Cilag Gmbh International | Surgical instrument with a hardware-only control circuit |
| US11166772B2 (en) | 2017-12-28 | 2021-11-09 | Cilag Gmbh International | Surgical hub coordination of control and communication of operating room devices |
| US11903601B2 (en) | 2017-12-28 | 2024-02-20 | Cilag Gmbh International | Surgical instrument comprising a plurality of drive systems |
| US11076921B2 (en) | 2017-12-28 | 2021-08-03 | Cilag Gmbh International | Adaptive control program updates for surgical hubs |
| US11633237B2 (en) | 2017-12-28 | 2023-04-25 | Cilag Gmbh International | Usage and technique analysis of surgeon / staff performance against a baseline to optimize device utilization and performance for both current and future procedures |
| US10892995B2 (en) | 2017-12-28 | 2021-01-12 | Ethicon Llc | Surgical network determination of prioritization of communication, interaction, or processing based on system or device needs |
| US11202570B2 (en) | 2017-12-28 | 2021-12-21 | Cilag Gmbh International | Communication hub and storage device for storing parameters and status of a surgical device to be shared with cloud based analytics systems |
| US11832840B2 (en) | 2017-12-28 | 2023-12-05 | Cilag Gmbh International | Surgical instrument having a flexible circuit |
| US11311306B2 (en) | 2017-12-28 | 2022-04-26 | Cilag Gmbh International | Surgical systems for detecting end effector tissue distribution irregularities |
| US11132462B2 (en) | 2017-12-28 | 2021-09-28 | Cilag Gmbh International | Data stripping method to interrogate patient records and create anonymized record |
| US11969216B2 (en) | 2017-12-28 | 2024-04-30 | Cilag Gmbh International | Surgical network recommendations from real time analysis of procedure variables against a baseline highlighting differences from the optimal solution |
| US20190201112A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Computer implemented interactive surgical systems |
| US11937769B2 (en) | 2017-12-28 | 2024-03-26 | Cilag Gmbh International | Method of hub communication, processing, storage and display |
| US11389164B2 (en) | 2017-12-28 | 2022-07-19 | Cilag Gmbh International | Method of using reinforced flexible circuits with multiple sensors to optimize performance of radio frequency devices |
| US11304699B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Method for adaptive control schemes for surgical network control and interaction |
| US11896443B2 (en) | 2017-12-28 | 2024-02-13 | Cilag Gmbh International | Control of a surgical system through a surgical barrier |
| US12396806B2 (en) | 2017-12-28 | 2025-08-26 | Cilag Gmbh International | Adjustment of a surgical device function based on situational awareness |
| US11672605B2 (en) | 2017-12-28 | 2023-06-13 | Cilag Gmbh International | Sterile field interactive control displays |
| US20190206569A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Method of cloud based data analytics for use with the hub |
| US11304763B2 (en) | 2017-12-28 | 2022-04-19 | Cilag Gmbh International | Image capturing of the areas outside the abdomen to improve placement and control of a surgical device in use |
| US11864728B2 (en) | 2017-12-28 | 2024-01-09 | Cilag Gmbh International | Characterization of tissue irregularities through the use of mono-chromatic light refractivity |
| US11559308B2 (en) | 2017-12-28 | 2023-01-24 | Cilag Gmbh International | Method for smart energy device infrastructure |
| US11786245B2 (en) | 2017-12-28 | 2023-10-17 | Cilag Gmbh International | Surgical systems with prioritized data transmission capabilities |
| US11612444B2 (en) | 2017-12-28 | 2023-03-28 | Cilag Gmbh International | Adjustment of a surgical device function based on situational awareness |
| US12062442B2 (en) | 2017-12-28 | 2024-08-13 | Cilag Gmbh International | Method for operating surgical instrument systems |
| US20190201042A1 (en) | 2017-12-28 | 2019-07-04 | Ethicon Llc | Determining the state of an ultrasonic electromechanical system according to frequency shift |
| US11818052B2 (en) | 2017-12-28 | 2023-11-14 | Cilag Gmbh International | Surgical network determination of prioritization of communication, interaction, or processing based on system or device needs |
| US11589915B2 (en) | 2018-03-08 | 2023-02-28 | Cilag Gmbh International | In-the-jaw classifier based on a model |
| US11259830B2 (en) | 2018-03-08 | 2022-03-01 | Cilag Gmbh International | Methods for controlling temperature in ultrasonic device |
| US12303159B2 (en) | 2018-03-08 | 2025-05-20 | Cilag Gmbh International | Methods for estimating and controlling state of ultrasonic end effector |
| US11839396B2 (en) | 2018-03-08 | 2023-12-12 | Cilag Gmbh International | Fine dissection mode for tissue classification |
| US11090047B2 (en) | 2018-03-28 | 2021-08-17 | Cilag Gmbh International | Surgical instrument comprising an adaptive control system |
| US11259806B2 (en) | 2018-03-28 | 2022-03-01 | Cilag Gmbh International | Surgical stapling devices with features for blocking advancement of a camming assembly of an incompatible cartridge installed therein |
| US11517309B2 (en) | 2019-02-19 | 2022-12-06 | Cilag Gmbh International | Staple cartridge retainer with retractable authentication key |
| US11464511B2 (en) | 2019-02-19 | 2022-10-11 | Cilag Gmbh International | Surgical staple cartridges with movable authentication key arrangements |
| CN109953749A (zh) * | 2019-04-19 | 2019-07-02 | 中国医学科学院生物医学工程研究所 | 基于小间距参考通道的表层干扰在线去除装置及其方法 |
| US11531112B2 (en) | 2019-06-20 | 2022-12-20 | Cilag Gmbh International | Offset illumination of a scene using multiple emitters in a hyperspectral, fluorescence, and laser mapping imaging system |
| US11903563B2 (en) | 2019-06-20 | 2024-02-20 | Cilag Gmbh International | Offset illumination of a scene using multiple emitters in a fluorescence imaging system |
| US11931009B2 (en) | 2019-06-20 | 2024-03-19 | Cilag Gmbh International | Offset illumination of a scene using multiple emitters in a hyperspectral imaging system |
| EP4312765A4 (en) | 2021-04-02 | 2025-01-15 | Nirsense LLC | Near-infrared spectroscopy systems and methods |
| EP4559373A1 (de) | 2023-11-24 | 2025-05-28 | Erbe Elektromedizin GmbH | Endoskop mit sensor zur bildaufnahme und gewebeuntersuchung |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62278436A (ja) * | 1986-05-28 | 1987-12-03 | Hitachi Ltd | 蛍光測定法及び装置 |
| AU3970799A (en) * | 1998-05-04 | 1999-11-23 | Board Of Regents | Combined fluorescence and reflectance spectroscopy |
| US6219566B1 (en) * | 1999-07-13 | 2001-04-17 | Photonics Research Ontario | Method of measuring concentration of luminescent materials in turbid media |
| US6697652B2 (en) | 2001-01-19 | 2004-02-24 | Massachusetts Institute Of Technology | Fluorescence, reflectance and light scattering spectroscopy for measuring tissue |
| US8238993B2 (en) * | 2002-04-04 | 2012-08-07 | Veralight, Inc. | Determination of a measure of a glycation end-product or disease state using tissue fluorescence lifetime |
| JP2004290234A (ja) * | 2003-03-25 | 2004-10-21 | Shiseido Co Ltd | 皮膚の蛍光測定方法およびその装置 |
| US20090270702A1 (en) * | 2005-01-21 | 2009-10-29 | Haishan Zeng | Method and apparatus for measuring cancerous changes from reflectance spectral measurements obtained during endoscopic imaging |
| JP2009516847A (ja) * | 2005-11-23 | 2009-04-23 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 混濁媒体の内部を画像化する装置 |
| JP2008197088A (ja) * | 2007-01-19 | 2008-08-28 | Shimadzu Corp | 蛍光検出器 |
| US8520921B2 (en) * | 2008-03-27 | 2013-08-27 | Koninklijke Philips Electronics N.V. | Method for reconstructing a fluorescent image of the interior of a turbid medium and device for imaging the interior of a turbid medium |
| WO2009153719A1 (en) | 2008-06-17 | 2009-12-23 | Koninklijke Philips Electronics N.V. | Method and device for optically examining the interior of turbid media |
| US20100249607A1 (en) * | 2008-09-26 | 2010-09-30 | Massachusetts Institute Of Technology | Quantitative spectroscopic imaging |
| EP2725965A1 (en) * | 2011-06-28 | 2014-05-07 | Koninklijke Philips N.V. | Needle with an optical fiber integrated in an elongated insert |
-
2012
- 2012-06-21 JP JP2014518003A patent/JP6093761B2/ja not_active Expired - Fee Related
- 2012-06-21 US US14/127,719 patent/US20140117256A1/en not_active Abandoned
- 2012-06-21 EP EP12740211.3A patent/EP2725967B1/en active Active
- 2012-06-21 BR BR112013033226A patent/BR112013033226A2/pt not_active IP Right Cessation
- 2012-06-21 CN CN201280032014.0A patent/CN103635131B/zh not_active Expired - Fee Related
- 2012-06-21 WO PCT/IB2012/053133 patent/WO2013001423A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20140117256A1 (en) | 2014-05-01 |
| CN103635131A (zh) | 2014-03-12 |
| EP2725967A1 (en) | 2014-05-07 |
| WO2013001423A1 (en) | 2013-01-03 |
| EP2725967B1 (en) | 2020-08-05 |
| BR112013033226A2 (pt) | 2017-03-01 |
| CN103635131B (zh) | 2018-07-27 |
| JP2014518390A (ja) | 2014-07-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6093761B2 (ja) | 関連した組織サンプルの光学的分析に対する装置 | |
| US11656448B2 (en) | Method and apparatus for quantitative hyperspectral fluorescence and reflectance imaging for surgical guidance | |
| US11406367B2 (en) | System with photonic biopsy device for obtaining pathological information | |
| US6564088B1 (en) | Probe for localized tissue spectroscopy | |
| JP6243226B2 (ja) | 関連組織の光学分析のための装置 | |
| RU2639037C2 (ru) | Биопсийная игла с большим межволоконным расстоянием на наконечнике | |
| CN105578970A (zh) | 活检装置和使用活检装置得到组织体积的层析图像的方法 | |
| US12061328B2 (en) | Method and apparatus for quantitative hyperspectral fluorescence and reflectance imaging for surgical guidance | |
| JP6231016B2 (ja) | 関連組織を光学的に分析するための機器 | |
| JP5674683B2 (ja) | 混濁媒体に少なくとも部分的に挿入されるよう構成される光学検査デバイス | |
| Yu et al. | Near-infrared spectral imaging of the female breast for quantitative oximetry in optical mammography | |
| WO2012127378A1 (en) | An apparatus for optical analysis of an associated tissue sample | |
| EP1797818A2 (en) | Method and system for tomographic imaging using fluorescent proteins | |
| WO2009122342A1 (en) | Method and device for visualizing accumulation or depletion of a contrast agent in a turbid medium | |
| Gamm et al. | In-‐Vivo Quantification of the Scattering Properties of Tissue using Multi Diameter Single Fiber Reflectance Spectroscopy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150520 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150520 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20160316 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160329 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20160628 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160927 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20170117 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170213 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6093761 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| LAPS | Cancellation because of no payment of annual fees |