JP6091576B2 - Polymethylmethacrylate bone cement mixing and storage equipment - Google Patents

Description

  The present invention provides a mixing system for mixing polymethylmethacrylate bone cement (PMMA bone cement) from two starting components, in particular for mixing medical bone cement, and for storage of starting components. Related.

  The invention further relates to a method for mixing polymethylmethacrylate bone cement.

  The subject of the present invention is therefore a polymethylmethacrylate bone cement storage and mixing device and a polymethylmethacrylate bone cement mixing method.

  Polymethylmethacrylate (PMMA) bone cement is based on the pioneering work of Charnley (Charnley, J. Fixation of artificial femoral head of the femoral shaft. J. Bone Joint Surg. 42 (1960) 28-30.) . PMMA bone cement consists of a liquid monomer component and a powder component. The monomer component generally includes a monomer (methyl methacrylate) and an activator (N, N-dimethyl-p-toluidine) dissolved therein. The flour component (also referred to as bone cement powder) includes one or more polymers, a radiopaque and a dibenzoyl peroxide initiator. The powder component polymer is made on the basis of methyl methacrylate and comonomers (eg styrene, methyl acrylate) or similar monomers, for example by polymerization, preferably by suspension polymerization. During the mixing of the flour component and the monomer component, the swelling of the methyl methacrylate polymer component is a real bone cement, producing a dough that can be plastically shaped. During the mixing of the flour and monomer components, the activator (N, N-dimethyl-p-toluidine) forms radicals and reacts with dibenzoyl peroxide. Thus, the radicals formed initiate radical polymerization of methyl methacrylate. In advancing the polymerization of methyl methacrylate, the viscosity of the cement dough increases until the cement dough solidifies.

  Methyl methacrylate is the most commonly used monomer in polymethylmethacrylate bone cement. A redox initiator system usually consists of a peroxide, an accelerator, and (if applicable) a suitable reducing agent. Radicals are formed only when all the components of the redox initiator system work together. For this, the components of the redox initiator system in the separate starting components are appropriately arranged so that they cannot trigger radical polymerization. The starting ingredients are stable while their composition is fully provided and stored. Only when the two starting ingredients are mixed to make a cement dough, the components of the redox initiator system can react with each other before the liquid or powder reacts with each other before being stored separately in the two pastes. To form radicals that initiate radical polymerization of The radical polymerization then consumes the monomer and leads to the formation of the polymer. Thereby, the cement dough is in a state suitable for storage.

  Using a spatula, the PMMA bone cement can be mixed by mixing the cement powder and monomer liquid in a suitable mixing beaker. Air inclusions may occur and / or may be present in the cement dough so formed and may have adverse effects on the mechanical properties in a state suitable for storage and thus later on the bone It is a disadvantage of this procedure that cement destabilization may occur.

  Many vacuum cementing systems have been proposed to prevent air entrapment in bone cement fabrics. Some of which are listed below for exemplary purposes. Patent Documents 1-13. In the vacuum cementing system specified in this way, it is necessary to connect an external vacuum pump in order to generate negative pressure. They are usually actuated by compressed air that utilizes the Venturi principle. The compressed air required for the operation of the vacuum pump is supplied by a stationary compressed air facility or by an electrically operated compressor. In addition, it is also possible to use an electrically operated vacuum pump to generate a vacuum.

  A cementing system in which both cement powder and monomer liquid are already packaged in separate compartments of the mixing system and are mixed together in the cementing system only just before the use of the cement is the development of cementing technology. The closed fully packaged mixing system was proposed by the following literature. Patent Documents 14 to 19. The mixing system also requires an external vacuum source.

  U.S. Pat. No. 6,057,051 discloses a general mixing system having a two part prefabricated plunger for the termination of a cement cartridge. A combination of a gas permeable sterile plunger and a gas impermeable sealing plunger is used in this context. This principle of the closed vacuum mixing system is implemented in a closed cementing system “PALACOS® PRO” manufactured and sold by Heraeus Medical.

  U.S. Patent No. 6,057,077 proposes an apparatus in which polymethylmethacrylate bone cement powder is stored in a cartridge. Thereby, the cement powder is the amount of clearance between the particles of the cement powder corresponding to the entire capacity of the cartridge and the amount of monomer liquid required for the creation of bone cement dough using the cement powder stored in the cartridge Meet. The design of the device is such that the monomer liquid is supplied to the cartridge from above by the action of a vacuum. Thereby, a vacuum is applied to the vacuum connector on the underside of the cartridge for this purpose. As a result, the monomer liquid is drawn by the cement powder. Thereby, the air located in the gap between the cement particles is replaced with the monomer liquid. This therefore does not include mechanical mixing of the cement dough formed by the stirrer.

  There is a monomer liquid because the rapidly expanding cement powder particles form a gel-like barrier of approximately 1-2 cm after the monomer liquid enters the cement powder, preventing the movement of the monomer liquid through all cement powder. It is a disadvantage of this system that in some cases rapidly expanding cement powder cannot be mixed using this device. Moreover, it cannot be excluded that the monomer liquid is sucked through the vacuum connector after the monomer liquid is completely infiltrated into the cement powder under the action of vacuum. In this case, an insufficient amount of monomer liquid can be used for vulcanization by radical polymerization and / or mixing ratio. Thus, the concentration of bone cement can be inadvertently changed. Furthermore, it is a problem that the air surrounded between the cement powder particles is displaced from the top to the bottom by the monomer liquid. This is because air having a lower specific gravity compared to the monomer liquid tends to move upward in the cement powder and not downward in the direction of the vacuum connector.

  If a vacuum mixing system is used for cementing, an external vacuum pump needs to be provided. The vacuum pump is expensive and needs to be cleaned after use. In addition, a vacuum hose for connecting the vacuum pump to the vacuum mixing system is required. The vacuum hose needs to be enclosed in a vacuum mixing system. Thus, prior to mixing using a vacuum mixing system, the vacuum pump needs to be set up at a surgical location (OR) and must be connected to an energy source (eg, compressed air or power). The vacuum pump is then connected to the vacuum mixing system by a vacuum hose. The installation step takes costly OR time and is potentially error prone. Vacuum pumps and connecting conduits for vacuum mixing systems and for external energy sources and supply conduits are potentially light hazards and obstacles that can take up space and often interfere with busy procedures during surgery.

  An interesting concept was proposed in US Pat. Here, the cement powder is stored in an emptied cartridge. And the monomer liquid is located in another container. Opening the cartridge, which is maintained at negative pressure, causes the monomer liquid to be drawn into the cartridge without any entry of air. Bone cement fabric without air inclusion is therefore made. The concept requires that the cartridge remain vacuum tight and closed during storage prior to use so that non-sterile air cannot enter the cartridge. For this purpose, the cartridge must be sealed in a stable and sealed manner. Thus, one related disadvantage is that the design is quite elaborate, and the feedthrough for the mixing rod or mixing tube is not immediately permanently vacuum-tight so that after external suction of the monomer liquid, This means that the contents of the cartridge cannot be mixed by the mixing system that has been activated. All fully packaged mixing systems known to date utilize vacuum or negative pressure to transfer the monomer liquid to the cement powder.

US Pat. No. 6,033,105A US Pat. No. 5,624,184A US Pat. No. 4,671,263A US Pat. No. 4,973,168A US Pat. No. 5,100,241A International Publication No. 99 / 67015A1 European Patent No. 1020167A2 US Pat. No. 5,586,821A European Patent No. 1016452A2 German Patent No. 3640279A1 International Publication No. 94 / 26403A1 European Patent No. 1005901A2 US Pat. No. 5,344,232A European Patent No. 06922929A1 German Patent Application Publication No. 102009031178B3 US Pat. No. 5,997,544A US Pat. No. 6,709,149B1 German Patent No. 698172626T2 US Pat. No. 5,588,745A International Publication No. 00 / 35506A1 European Patent No. 1886647A1 German Patent No. 102010026496B4 US Pat. No. 8,662,736B4

  Therefore, it is an object of the present invention to overcome the disadvantages of the prior art. In particular, the disadvantages of known vacuum mixing systems with an external vacuum source should be overcome. One object of the present invention is to develop a simple, closed device. The polymethylmethacrylate bone cement powder (cement powder) and the monomer liquid can then be stored in separate compartments and then mixed. Without a medical user exposed to either of the two cement components, the medical user can combine and mix polymethylmethacrylate bone cement powder and monomer liquid inside the device. Any contact with the medical user's polymethylmethacrylate bone cement powder and with the monomer liquid is excluded as much as possible. The device to be developed is a fully packaged mixing system. The device is suitably designed so that the monomer liquid can be transferred to the polymethylmethacrylate bone cement powder without the use of compressed air or an external vacuum pump driven by a compressor. Furthermore, even under the simplest external conditions, the device is functional in the absence of an external energy source (eg compressed air, vacuum or current) and that ensures the production of bone cement fabric That is important. Autonomous devices without additional technical equipment can be used.

  It is another object of the present invention to provide an apparatus that makes it possible to specifically control the amount of monomer liquid transferred to the cement dough. Then, the ratio of the amount of monomer liquid to the amount of cement powder can be varied in order to control the bone cement concentration and thus the processing properties of the bone cement.

  Furthermore, a method should be provided that allows for the transfer of monomers and mixing of fully packaged mixing systems. In this context, the mixing systems that are developed are mainly manufactured from inexpensive plastics.

  In addition, it is inexpensive to manufacture and the work for mixing medical cement is reliable and, where appropriate, equipment for storage of the cement's starting components, and for mixing bone cement A method is devised. And where appropriate, simple manual operation can be used to mix the starting components without the need to use an external or additional energy source and without the air inclusion that occurs in the mixed material. .

  The main component as a mixed material of polymethylmethacrylate bone cement is powder. The second component exists in a liquid form. Preferably, the two starting components of a separate bone cement can be stored in a fully packaged mixing system and can be safely combined by using the device.

The object of the invention is an apparatus for mixing polymethylmethacrylate bone cement (PMMA bone cement) and for storing bone cement starting components, in particular monomer liquids and cement powder as starting components of bone cement. There,
1) a cartridge having an internal space for mixing bone cement, which is closed on one side by a movable pre-made plunger;
2) For the installation of the monomer container for the monomer liquid and / or the monomer container for the monomer liquid so that the monomer container can be properly opened in the apparatus so that the monomer liquid flows from the monomer container to the apparatus connector,
3) comprising a connecting conduit through which the monomer liquid can be led to the interior space of the cartridge, thereby
4) A hollow cylinder is connected to the connecting conduit, and the hollow cylinder is disposed between the monomer container or the connector for the monomer container and the inner space of the cartridge, and thereby displaced axially in the hollow cylinder. A pumping plunger is arranged in the hollow cylinder, so that the monomer liquid can flow from the opened monomer container to the hollow cylinder and the connecting conduit properly connects the hollow cylinder to the interior space of the cartridge Thus, by actuating the pumping plunger, the pumping plunger is addressed by an apparatus that can be used to push the monomer liquid from the hollow cylinder through the connecting conduit and into the interior space of the cartridge.

  The hollow cylinder disposed between the monomer container for the monomer liquid or the connector for the monomer container and the cartridge does not mean that the hollow cylinder is geometrically disposed therebetween. Rather, when the monomer liquid flows and / or is pumped out of the opened monomer container in the direction of the cartridge, it relates to the monomer container or connector for the monomer container with respect to the fluid connection (ie, the flow direction of the monomer liquid). , Between the cartridge.

  For the monomer liquid flowing from the opened monomer container to the hollow cylinder, the opened monomer container is connected to the hollow cylinder for this purpose, preferably connected to the hollow cylinder by a junction.

  For monomer liquids that can flow without the action of additional forces, the device must be assembled according to the intended purpose so that gravity performs the desired flow direction. Accordingly, the terms top and bottom, top and bottom, and top and bottom, as used in the scope of the present invention, are always understood with respect to the assembly of the device for the intended purpose.

  The interior space of the cartridge preferably has a geometric cylinder. The cylindrical shape is the simplest shape that the interior space of the cartridge and the hollow cylinder can be implemented. A cylindrical internal shape is understood geometrically to mean a general cylinder with any footprint (ie not a cylinder with a just circular footprint). Thus, the inner wall of the interior space can be a cylinder with any footprint. The hollow cylindrical jacket can then be a cylinder with any footprint (ie, including a non-circular or circular footprint). However, a geometric cylinder with a rotationally symmetric footprint is preferred according to the invention.

  In order to achieve a good pumping effect and to prevent leakage of monomer liquid from the pumping plunger, the pumping plunger is closed in a fluid tight manner with respect to the inner wall of the hollow cylinder. For this purpose, a circumferential seal can be provided that separates the pumping plunger with respect to the inner wall of the hollow cylinder.

  According to the present invention, it is preferred to have a monomer container that is attached to the connector for the monomer container, or to have a monomer container that is inserted into the connector for the monomer container.

  Preferably, the polymethylmethacrylate bone cement can be mixed and / or produced from at least two components. Particularly preferably, one component is a liquid (monomer liquid) and the other component is a powder.

  According to the invention, the starting components for the mixed material, in particular for PMMA bone cement, are already present in the cartridge and monomer container.

  According to the present invention, the device is also preferably suitable for storage of starting components, especially when the container is inserted into the device or when the container is a fixed part of the device. .

  The present invention places a mixing facility in the cartridge that can be actuated from the outside, whereby the mixing facility is guided through the feedthrough of the prefabricated plunger into the interior of the cartridge, e.g. a movable support. It is proposed that it can preferably be actuated by a mixing rod supported like a surface.

  Particularly preferably, the mixing rod can be rotated in the feedthrough and is supported like a support surface so as to be displaceable in the longitudinal direction, for example. By means of the mixing facility, the contents of the interior space of the cartridge can be conveniently mixed by means of a mixing rod. Referring to the use of low viscosity bone cement, it is possible to dispense with the use of mixing rods and mixing equipment. This is because the monomer liquid moves the air in the pores between the cement powder particles and wets the cement powder particles before the cement powder expands.

  The present invention can additionally provide a prefabricated plunger that is impermeable to powder. Thereby, it is preferred to have a pore filter that is permeable to gas and impermeable to powder, which is arranged in the preformed plunger.

  Hole filtering can preferably be provided as a hole disk. The impermeability to the powder can prevent the cement powder from leaking from the inside of the cartridge. If the preformed plunger is gas permeable, the interior space can be emptied and sterilized, for example, by a gas (eg, ethylene oxide) passing through the preformed plunger.

  The present invention also proposes cement powder contained in the internal space of the cartridge.

  The present invention can further provide a monomer liquid contained in the monomer container. As a result, the device forms a ready-made, fully packaged mixing system that does not need to be filled with cement powder prior to application. The cement powder is stored in a separate cartridge from the monomer liquid before use.

  Furthermore, the present invention can provide a filter that is disposed between the connecting conduit and the interior space of the cartridge and is impermeable to cement powder and permeable to monomer liquid.

  Cement powder penetrates the connecting conduit by this means, polymerizes in this space when the monomer liquid is fed, and inadvertently clogs and / or aggregates the connecting conduit. This can be prevented.

  According to a further development, the invention comprises a base in which at least a part of the connecting conduit is arranged, whereby the cartridge is connected to the base in a detachable manner, in particular detachable with a screw. And, where applicable, the cement powder impervious and monomer liquid permeable filter is preferably arranged at the base of the device, particularly preferably at the connection of the base to the cartridge. An apparatus can be provided.

  As a result, the device can be easily assembled and operated.

  In this context, the present invention provides a hollow cylinder and monomer container or a connector for attachment of a hollow cylinder and monomer container that is connected to the base and preferably connected to the base in an unreleasable manner. can do.

  This allows for a particularly simple and inexpensive design of the device.

  A preferred embodiment of the present invention is for the attachment of a monomer container or monomer container for a monomer liquid to terminate in a hollow cylinder on the jacket surface of the hollow cylinder and preferably terminate in the hollow cylinder just below the pumping plunger. A connector can be provided.

  By this means it can be ensured that all of the monomer liquid can flow into the hollow cylinder and fill the hollow cylinder. Furthermore, the air can be discharged particularly easily from the hollow cylinder in this position.

  Furthermore, the present invention comprises an opening means for opening the monomer container, by which the monomer container can be opened inside the connection device, whereby the opened monomer container fragments or small pieces are retained. Having a sieve or filter placed at the connection to the hollow cylinder can provide a preferred device.

  In this context, it may be preferable to provide a monomer container that is a fragile glass ampoule.

  With the opening means being part of the device, the device can be used for monomer storage as well over time. Suitable opening means are known, for example, from US Pat.

  The improvements of the present invention, including the use of gravity to cause the flow of monomer liquid into the hollow cylinder, propose a monomer container that is positioned above the connection to the hollow cylinder.

  As a result, after the monomer container is opened, gravity causes the monomer liquid to flow from the monomer container to the hollow cylinder. Alternatively, the monomer is better squeezed out and therefore flows into the hollow cylinder.

  A preferred device has a connecting conduit connected to the hollow cylinder on the lower side, preferably connected to the hollow cylinder at the lowest point of the hollow cylinder, thereby providing a pumping plunger disposed on the opposite side of the hollow cylinder. It can be characterized as well by being particularly preferred.

  As a result, all the monomer liquid can flow out and / or be squeezed from the pumping plunger.

  The present invention further includes a conical, hemispherical, or any other downwardly tapered floor on the opposite side of the pumping plunger from the hollow cylinder, thereby providing a pumping plunger facing the hollow cylindrical floor. The surface preferably proposes to form a negative image of the floor.

  As a result, all the monomer liquid can flow out and / or be squeezed from the pumping plunger. This means that there is all monomer liquid flow to the lowest point of the hollow cylinder and no “dead” space. The monomer liquid then remains behind during the operation of the pumping plunger. Due to the adaptation of the shape of the pumping plunger to the internal shape of the hollow cylinder, all monomer liquid will be transferred from the hollow cylinder to the connecting conduit in response to the operation of the pumping plunger without any residual monomer liquid remaining in the hollow cylinder. It is pressed by the pumping plunger in the direction of the opening that is heading. Further, the front of the pumping plunger having the conical or spherical surface and / or the matching shape is such that when the pumping plunger moves down and / or toward the base, the air above the monomer liquid in the hollow cylinder Ensure that it can leak through the opening in the jacket surface and that no bubbles remain above the monomer liquid during the transfer of the monomer liquid to the interior space of the cartridge and / or to the cement powder.

  A preferred embodiment provides that the pumping plunger can be moved axially in the hollow cylinder by hand, and can preferably be pushed axially in the hollow cylinder by hand.

  As a result, it is possible to manually push the monomer liquid from the hollow cylinder and transfer it to the internal space of the cartridge.

  In order to simplify the operation and to provide more variability of the device according to the invention, the present invention additionally provides a hollow cylinder with markings that are transparent and indicate the level of liquid filling in the hollow cylinder. Can be provided.

  By this means, the amount of monomer liquid measured at the marking can be filled into the hollow cylinder and / or pressed from the hollow cylinder into the interior space of the cartridge. This gives the option to use the device to produce a bone cement dough whose concentration is given by the amount of monomer. Alternatively, in order to allow a defined advancement of the pumping plunger and thus to be able to press a defined amount of monomer liquid from the hollow cylinder, the hollow cylinder cannot be transparent as well, The marking can then be provided on the end of the pumping plunger protruding from the hollow cylinder. Therefore, for this type of design, press all the amount of monomer liquid from the hollow cylinder to the cement powder in the cartridge's internal space, and transfer only the part quantity of monomer liquid from the hollow cylinder to the cement powder. Either of these is possible. By this means, the ratio of the monomer liquid to the amount of powder can be adjusted. And it allows a period of time until the cement dough thus formed does not stick, as well as the viscosity of the bone cement that is specifically controlled.

  The present invention relates to a hollow cylinder with an internal thread and a pumping plunger with an external thread to be screwed so that the pumping plunger can be screwed into the hollow cylinder in order to press the monomer liquid from the hollow cylinder into the interior space of the cartridge. On top of that.

  This also allows a defined amount of monomer liquid to be pressed from the hollow cylinder into the interior space of the cartridge. This gives the option to use the device to create a bone cement dough whose concentration is determined by the amount of monomer liquid.

  Alternatively, the present invention comprises a tensioned compression spring and locking mechanism, whereby the compression spring and / or pumping plunger is locked by the locking mechanism in a releasable manner, thereby releasing the locking mechanism. When done, the compression spring can provide a device that exerts pressure on the pumping plunger in the sense that the pumping plunger is pressed into the hollow cylinder (62).

  Similarly, in an embodiment where the hollow cylinder comprises an internal thread and the pumping plunger comprises an external thread, the present invention provides a tensioned rotary spring that screws the pumping plunger into the hollow cylinder after the locking mechanism is released. can do.

  These means are advantageous in that they simplify the operation of the device. Furthermore, possible erroneous operations can thus be prevented.

  Furthermore, the present invention is connected to the cartridge by a releasable snap-type device so that the prefabricated plunger can move axially in the interior space of the cartridge, whereby the snap-type device is A prefabricated plunger can be provided that can be released manually, particularly by the action of an axial force.

  By this means, inadvertent movement of the prefabricated plunger, such as may occur due to, for example, a vacuum in the interior space of the cartridge, can be prevented.

  To prevent the cartridge interior space from being inadvertently filled with the monomer liquid, the present invention provides a connecting conduit between the hollow cylinder and the cartridge interior space to provide an upward loop, whereby The uppermost position of the loop can provide a connecting conduit above the junction of the monomer container or connector for the monomer container to the hollow cylinder.

  By this means, the monomer liquid can be prevented from reaching the interior space of the cartridge through the connecting conduit while it is already filled in the hollow cylinder. The effect of the inverted U-shaped loop of the connecting conduit is that the monomer liquid in the hollow cylinder remains in the connecting conduit to the top level before the pumping plunger moves toward the connecting conduit toward the cartridge. It is. Thereby, premature entry of the monomer liquid toward the cement powder is prevented. Especially in the case of high viscosity cements, as described in U.S. Pat. No. 8,662,736 B2, any premature contact of the monomer liquid with cement powder, even in very small amounts, is provided in the form of a connecting conduit or in the form of a nozzle. It can lead to clogging of means. The connecting conduit can be transparent or translucent so that the user can visually inspect the transport of the monomer. For this purpose, in particular an inspection window can be provided in the device in which the loop with the highest vertex can be seen.

  Furthermore, the present invention can provide a hollow cylinder volume that is less than or equal to the amount of monomer liquid in the monomer container.

  This prevents air from being pushed along the cement powder when the pumping plunger is actuated.

  Furthermore, the present invention can provide an interior space of the cartridge which is connected to the connecting conduit in a liquid permeable manner on the underside thereof.

  According to Patent Document 23, the connecting conduit can go out to the nozzle in front of the interior space. The nozzle prevents any entry of cement powder into the connection means.

  In another variant of the embodiment, the interior space of the cartridge is connected on the jacket surface transverse to the connecting conduit in a liquid permeable manner. By this means it is furthermore possible to transfer the monomer liquid via the side to the cement powder in the interior space of the cartridge.

  Preferably, the hollow cylinder, cartridge and connecting conduit, and, if present, the base, mixing equipment and mixing rod are made of plastic material and can be manufactured inexpensively by plastic injection molding.

The object underlying the present invention is also a method for mixing bone cement, in particular by means of the device according to the invention, comprising the following time course steps:
A) the step of opening the monomer container;
B) the monomer liquid flows from the monomer container to the hollow cylinder, whereby the hollow cylinder borders on one side by a pumping plunger;
C) The pumping plunger is pushed into the hollow cylinder so that the monomer liquid is pushed from the hollow cylinder and through the connecting conduit into the interior space of the cartridge, thereby causing the cement powder to enter the interior space of the cartridge. Steps located in and
D) the monomer solution and the cement powder are mixed in the interior space of the cartridge.

  Preferably, the monomer liquid flows into the hollow cylinder by the action of gravity.

  In this context, the present invention is mixed in the interior space of the cartridge only once the pumping plunger is pushed fully into the hollow cylinder or up to the marking, whereby the marking is fed into the interior space of the cartridge Monomer liquid and cement powder can be provided that are metering for the monomer liquid.

  As a result, the resulting bone cement dough can be guaranteed to reach the desired concentration with the desired mixture of monomer liquids.

  The present invention also provides monomer liquid and cement by manipulating the mixing equipment by moving a mixing rod that is guided into the interior space of the cartridge so that it can be rotated and displaced longitudinally. The powder is mixed in the internal space by the mixing equipment, whereby preferably the mixing rod is withdrawn from the internal space of the cartridge to the limit stop after mixing, and particularly preferably after being extracted to the limit stop, It is proposed that the mixing rod be folded at a predetermined breakage site.

  As a result, the method can be easily performed by manual operation.

  Furthermore, the present invention provides a monomer container that is preferably opened by actuating or activating the opening means, thereby having a monomer container that is broken to open by the opening means. Can do.

  As a result, the monomer container can be opened inside the device so that the entire device is closed with respect to the outside.

  The invention also provides a locking mechanism in which the pumping plunger is pushed into the hollow cylinder by a tensioned elastic spring element, thereby engaging the pumping plunger and / or the spring element for this purpose. We suggest that it is preferable to release.

  This achieves further optimization of the method according to the invention and additionally prevents possible misoperation.

  And finally, the cartridge with raw cement dough is released from the connecting conduit, hollow cylinder, and monomer container and is supported so as to be axially movable within the cartridge and on one side the cartridge By advancing the prefabricated plunger bordering the interior space of the interior, the raw cement dough can be provided to be prefabricated from the interior space of the cartridge.

  The present invention is based on the surprising discovery that the monomer liquid can be pushed from below into the interior space of the cartridge by the pumping plunger without any interfering air inclusions simultaneously forming in the bone cement. As a result, the device can be used primarily without an external energy source or internal energy storage. In particular, there is no need to use vacuum sources and vacuum-type connectors and components. And it greatly simplifies use in less developed locations as well as in local or field hospitals. Furthermore, the fully packaged mixing system according to the present invention is not affected by possible obstacles since a vacuum leak cannot occur and is therefore likely to be very ready for use.

  The device according to the invention and / or the method according to the invention can be used after the monomer container has been opened, for example for the monomer liquid to flow into the hollow cylinder by the action of gravity and from the hollow cylinder by manual operation of the pumping plunger. It can be provided to be pushed into the interior space of the cartridge containing the powder. This means that the transfer of the monomer liquid proceeds by the action of pressure rather than the action of vacuum. And it is now on the market as opposed to a mixing system. Said monomer transfer by the action of pressure carried out by hand can be realized inexpensively using simple plastic parts which can be made by plastic injection molding. A particular advantage of the device according to the invention is that the device can be operated in the absence of external assistance (eg compressed air vacuum pump) and in the absence of an external energy source (eg compressed air or current). That's what it means. As a result, the device according to the invention can be used autonomously and even under the simplest operating conditions. The device according to the invention provides a closed fully packaged mixing system for the price sensitive market.

  It is clear within the scope of the present invention that the monomer liquid supplied from below the interior space of the cartridge to the cement powder through the action of pressure is transferred from the bottom of the uniform front to the top. By this means, the air present in the gaps between the cement powder particles is displaced and pushed out toward the top. As a result, air inclusion is prevented. It is surprisingly clear within the scope of the present invention that the bone cement fabric made by the device according to the invention and the method according to the invention is essentially free of air and has a quality equal to that of a cement fabric made in a vacuum. It is.

  Further exemplary embodiments of the invention are illustrated below on the basis of seven schematic diagrams, without limiting the scope of the invention.

FIG. 1 shows a schematic perspective view of a device according to the invention in the form of a fully packaged mixing system. FIG. 2 shows a top view with two cross sections A and B of the device according to FIG. 3 shows the device according to FIGS. 1 and 2 in a schematic cross-sectional view corresponding to the cross-section A according to FIG. 4 shows details of the device according to FIGS. 1, 2 and 3 in a schematic cross-sectional view corresponding to the cross-section B according to FIG. FIG. 5 shows a schematic perspective view of an alternative device according to the invention in the form of a fully packaged mixing system. FIG. 6 shows the device according to FIG. 5 in a schematic sectional view. FIG. 7 shows a schematic cross-sectional view of the details of the device according to FIGS. 4 and 5, ie a hollow cylinder with a clamp as a locking mechanism for a compression spring.

  The cleavage planes of the cross-sectional views of FIGS. 3, 4, 6 and 7 are confirmed by hatching.

  1 to 4 show schematic views of a first apparatus according to the invention which is suitable for carrying out the method according to the invention. In this context, FIG. 1 shows a schematic perspective view of the device according to the invention in the form of a fully packaged mixing system, and FIG. 2 shows a top view with two sections A and B of the device according to FIG. 3 shows the device according to FIGS. 1 and 2 in a schematic cross-sectional view corresponding to section A according to FIG. 2, and FIG. 4 in a schematic cross-sectional view corresponding to section B according to FIG. FIG. 4 shows details of the device according to FIGS. 1, 2 and 3.

  The device comprises a cartridge 1 containing cement powder as a starting component of the PMMA bone cement being made. The cartridge 1 is closed on the upper side (the upper part in FIGS. 1 and 3 and the direction of the observer in FIG. 2) by the prefabricated plunger 2. The prefabricated plunger 2 can be locked with respect to the wall of the cartridge 1. The vacuum connector 3 is provided on the preformed plunger 2 and can be used to empty the inside of the cartridge 1. Theoretically, ethylene oxide can be filled through the vacuum connector 3 for sterilization of the contents of the cartridge 1. The mixing rod 4 is guided through the central feedthrough to the prefabricated plunger 2 and can be drawn into and withdrawn from the cartridge 1 so that it can rotate in the prefabricated plunger 2 and thus in the cartridge 1. It is supported like a support surface. A handle portion 6 for manual operation of the mixing rod 4 is attached to the upper end of the mixing rod 4 (upper part in FIGS. 1 and 3 and the direction of the observer in FIG. 2).

  The cartridge 1 is attached to the base 10 in a releasable manner in the area of the socket 8 on the base 10 of the device. To be provided in the same part as the base 10, the hollow cylinder 12 has a pumping plunger 14 disposed on top of the base 10 and disposed therein. And it can be pushed and / or pushed into the inside of the hollow cylinder 12 (downward in FIGS. 1 and 3, from the direction of the observer in FIG. 2 to the screen), fitting inside it .

  Apart from the hollow cylinder 12, there is a connection socket 18 which is provided on the base 10 and forms part of the connector 20 for the monomer container 46 of the device. Apart from the connection socket 18, the connector 20 for the monomer container 46 can be closed with respect to the outside after the elastic receptacle 21 for the monomer container 46 and the monomer container 46 have been inserted. A lid 22 is provided. A monomer container 46 is placed inside the connector 20 and in the device. The monomer container 46 is a glass ampoule filled with a monomer liquid as a second component for the PMMA bone cement being made. The elastic receptacle 21 is made of rubber or other elastic plastic material.

  Details regarding the design of the device are apparent from FIGS. The inner side of the cartridge 1 is formed by a cylindrical inner space 24 containing cement powder. Furthermore, the internal space 24 of the cartridge 1 has a mixing facility 26 that is attached to the mixing rod 4 and includes a plurality of mixing blades 26 that are arranged so that the internal space 24 can be moved by the mixing rod 4. The prefabricated plunger 2 is designed to be two parts, a sterilizing plunger 28 (top of the prefabricated plunger of FIG. 3) and a sealing plunger 30 (FIG. 3) that is sealed against the inner wall of the interior space 24 by a seal 29. The lower part of the pre-made plunger. The sealing plunger 30 comprises a perforated disk that is gas permeable but powder impervious through which the interior space 24 can be emptied. The prefabricated plunger 2 has a cylindrical outer periphery and closes tightly against the wall of the internal space 24. The prefabricated plunger 2 can be propelled in the internal space 24 in the direction of the prefabricated opening arranged on the side of the internal space 24 of the cartridge 1 that is the opposite of the prefabricated plunger 2.

  For connection of the cartridge 1 to the base 10, a base connector 34 having an external thread and having a powder-impermeable and liquid-permeable filter 32 disposed thereon is provided as a connection to the cartridge 1. The cartridge connector 36 having a female screw that is screwed into the male screw of the base connector 34 is provided on the inner space 24 side of the cartridge 1 that is directly opposite to the pre-made plunger 2. The cartridge connector 36 contacts the prefabricated opening of the cartridge 1. The cartridge connector 36 is screwed to the base connector 34 and closes tightly thereto.

  The connecting conduit 34 is provided between the hollow cylinder 12 and the internal space 24 of the cartridge 1 to connect the hollow cylinder 12 to the internal space 24 of the cartridge 1. A filter 32 that prevents cement powder from entering the connecting conduit 38 from the interior space 24 of the cartridge 1 is disposed at the junction to the interior space 24 of the cartridge 1. The connecting conduit 38 forms a loop 40 with a high apex to prevent any uncontrolled movement of the monomer liquid through the connecting conduit 38 to the interior space 24 of the cartridge 1. A housing 16 with a small inspection window is provided for covering the loop 40 and for visual inspection.

  The connection socket 18 for the socket 8, the base 10, the hollow cylinder 12, the housing 16 and the monomer container 46 is made in the form of a single part from a plastic material, for example by injection molding. The hollow cylinder 12 is limited on its lower side (bottom in FIG. 3) by a funnel shaped floor 41 that tapers steadily in the downward direction. This ensures that all of the monomer liquid can flow and / or be pushed out of the hollow cylinder 12. The pumping plunger 14 is formed by a hollow body made of a plastic material and is shaped on the bottom surface 42 as a negative image of the floor 41 of the hollow cylinder 12. The pumping plunger 14 is sealed with respect to the inner wall of the hollow cylinder 12 by a seal 43 and is supported on the hollow cylinder 12 as a support surface so that it is movable in the longitudinal direction (downward in FIG. 3).

  The joint 44 of the connector 20 for the monomer container 46 to the hollow cylinder 12 is provided on the jacket surface of the hollow cylinder 12 just below the lower surface 42 of the pumping plunger 14. The joint 44 is a conduit means for the monomer liquid, so that the joint 44 can be interpreted as part of a connecting conduit 38, 44 for the monomer liquid having the hollow cylinder 12 disposed thereon. Form.

  A sieve 45 or filter 45 on which fragments and portions of the opened monomer container 46 can be trapped is located in the connector 20 for the monomer container 46. The monomer container 46 is a glass ampoule 46 having an ampoule head 47 that can be folded and a neck that can be broken open so that the neck can be used to connect the ampoule head 47 to the body of the ampoule 46. Connect to. Due to the elasticity of the receptacle 21 for the monomer container 46 and due to the receptacle 21 being unfolded in the region of the neck, the head of the monomer container 46 is bent by bending the receptacle 21 having the monomer container 46 therein. 47 can be folded. By this means, the receptacle 21 having a suitable shape, in particular a shape expanded in the region of the neck, forms an opening means 21 for opening the monomer container 46. Other opening means for cutting off the head 47 of the monomer container 46 can be implemented just as well.

  An inclined floor surface 48 that is inclined in the direction of the joint 44 is provided in the connection socket 18 under the sieve 45 and / or the filter 45. By this means, all the monomer liquid can flow from the monomer container 46 through the joint 44 to the hollow cylinder 12.

  The method according to the invention can be carried out by the apparatus according to FIGS. The device is placed by the base 10 on a table or on any other suitable level support. The monomer container 46 is opened by twisting the elastic receptacle 21 by folding and / or breaking the head 47 to open. The monomer liquid from the monomer container 46 flows through the sieve 45 and / or the filter 45. Thereby, the fragment of the monomer container 46 is retained. The inclined floor surface 48 guides the monomer liquid to the hollow cylinder 12 through the joint portion 44. The empty internal space of the hollow cylinder 12 is completely filled with the monomer liquid. This is because the monomer container 46 contains more monomer liquid than can be taken up by the hollow cylinder 12. The contained air escapes through the joint 44. This is because the joint 44 is located at the top of the space bounded by the hollow cylinder 12 and the pumping plunger 14. In this context, the loop 40 is positioned clearly above the junction 44 and is also positioned above the level of the monomer liquid in the connector 20 so that the monomer liquid does not rise to this level in the absence of pressure. As a result, the monomer liquid cannot flow beyond the top of the loop 40.

  Thereafter, in order to transfer and / or push the desired amount of monomer liquid from the hollow cylinder 12 through the connecting conduit 38 into the interior space 24 of the cartridge 1, the pumping plunger 14 is completely or completely inserted into the hollow cylinder 12. Can be partially pushed. By inserting the pumping plunger 14 into the hollow cylinder 12 to different depth levels, the amount of monomer liquid injected can be adjusted. For this purpose, markings (not shown) can be provided on the outside of the pumping plunger 14. Alternatively, the marking is located on the hollow cylinder 12, and the hollow cylinder 12 is made of a transparent material. The monomer liquid is pressed into the internal space 24 of the cartridge 1 through the filter 32. And then it rises and mixes with the cement powder stored in the internal space 24 of the cartridge 1.

  After the desired amount is filled in the internal space 24 of the cartridge 1, the mixing equipment 26 and / or the mixing rod 4 are pushed by the handle portion 6 and pulled out to manually mix the monomer liquid and cement powder. And rotated. The cement dough and / or PMMA bone cement is then mixed. After mixing is complete, the mixing rod 4 is withdrawn from the interior space 24 of the cartridge 1 until a limit stop and folded to ensure that it does not interfere at a later time. If applicable, the locking mechanism of the prefabricated plunger 2 can be released. Thereafter, the cartridge 1 can be unscrewed from the base 10 and a preformed tube (not shown) can be screwed onto the internal thread on the cartridge connector 36. Thereafter, the raw bone cement can be released from the interior space of the cartridge through the preform opening and the preform tube by pressing the preform plunger 2 inward. And raw bone cement can be applied.

  5 to 7 show schematic views of a second alternative device according to the invention which is suitable for carrying out the method according to the invention. In this context, FIG. 5 shows a schematic perspective view of an alternative device according to the invention in the form of a fully packaged mixing system, FIG. 6 shows the device according to FIG. FIG. 7 shows a schematic cross-sectional view of the details of the device according to FIGS. 4 and 5.

  The device comprises a cartridge 51 containing cement powder as a starting component of the PMMA bone cement being made. The cartridge 51 is closed on the upper side (the upper side in FIGS. 5 and 6) by the preformed plunger 52. The prefabricated plunger 52 can be locked with respect to the wall of the cartridge 51. The vacuum connector 53 is provided on the preformed plunger 52 and can be used to empty the interior of the cartridge 51. Theoretically, ethylene oxide can be filled through the vacuum connector 3 to sterilize the contents of the cartridge 51. The mixing rod 54 is guided through the central feedthrough to the prefabricated plunger 52 and can be drawn into and withdrawn from the cartridge 51 so that it can rotate at the prefabricated plunger 52 and thus at the cartridge 51. It is supported like a support surface. A handle portion 56 for manual operation of the mixing rod 54 is attached to the upper end of the mixing rod 54 (upper part of FIGS. 5 and 6).

  The cartridge 51 is attached to the base 60 in a releasable manner in the area of the socket 58 on the base 60 of the device. The hollow cylinder 62 closed by the screw lid 63 is provided as the same component as the base 60 and is disposed on the upper side of the base 60. A suitable pumping plunger 64 that can be pressed and / or pushed into the interior of the hollow cylinder 62 (downward in FIGS. 5 and 6) is disposed within the hollow cylinder 62. The pumping plunger 64 is locked by a clamp 65 acting as a locking mechanism 65 so that it cannot be brought into the interior of the hollow cylinder 62 without releasing the clamp 65 and / or the locking mechanism 65. The compression spring 67 that is tensioned against the screw lid 63 is disposed inside the pumping plunger 64. After the clamp 65 and / or the locking mechanism 65 is released by pulling it out (pulling upward in FIG. 7), the compression spring 67 pushes the pumping plunger 64 down into the hollow cylinder 62.

  Apart from the hollow cylinder 62, there is a connection socket 68 which is provided on the base 60 and forms part of the connector 70 for the monomer container 96 of the device. Apart from the connection socket 68, the connector 70 for the monomer container 96 can be closed with respect to the outside after the elastic receptacle 71 for the monomer container 96 and the monomer container 96 have been inserted. A lid 72 is provided. A monomer container 96 is placed inside the connector 70 and in the device. The monomer container 96 is a glass ampoule filled with a monomer liquid as a second component for the PMMA bone cement being made. The elastic receptacle 71 is made of rubber or other elastic plastic material.

  Details regarding the design of the device are apparent from FIGS. The inner side of the cartridge 51 is formed by a cylindrical inner space 74 containing cement powder. Furthermore, the internal space 74 of the cartridge 51 has a mixing facility 76 composed of a plurality of mixing blades 76 attached to the mixing rod 54 and arranged so as to be able to move through the internal space 74 by the mixing rod 54. The prefabricated plunger 52 is designed to be two parts and is a sterilizing plunger 78 (top of the prefabricated plunger of FIG. 6) and a sealing plunger 80 (FIG. The lower part of the pre-made plunger. The sealing plunger 80 comprises a perforated disc that is gas permeable but powder impervious through which the interior space 74 can be evacuated. The prefabricated plunger 52 has a cylindrical outer periphery and closes tightly against the wall of the internal space 74. The prefabricated plunger 52 can be propelled in the internal space 74 in the direction of a prefabricated opening that is disposed on the side of the internal space 74 of the cartridge 51 that is directly opposite to the prefabricated plunger 52.

  For connection of the cartridge 51 to the base 60, a base connector 84 having a male screw and having a powder-impermeable and liquid-permeable filter 82 disposed thereon is provided as a connection to the cartridge 51. A cartridge connector 86 having a female screw that is screwed into the male screw of the base connector 84 is provided on the inner space 74 side of the cartridge 51 that is directly opposite to the pre-made plunger 52. The cartridge connector 86 contacts the prefabricated opening of the cartridge 51. The cartridge connector 86 is screwed to the base connector 84 and closes tightly thereto.

  The connecting conduit 84 is provided between the hollow cylinder 62 and the internal space 74 of the cartridge 51, and connects the hollow cylinder 62 to the internal space 74 of the cartridge 51. A filter 82 that prevents cement powder from entering the connecting conduit 88 from the internal space 74 of the cartridge 51 is disposed at the junction of the cartridge 51 to the internal space 74. The connecting conduit 88 forms a loop 90 with a high apex to prevent any uncontrolled movement of monomer liquid through the connecting conduit 88 to the interior space 74 of the cartridge 51. A housing 66 with a small inspection window is provided for the loop 90 cover and visual inspection.

  The socket 58, the base 60, the hollow cylinder 62, the housing 66, and the connection socket 68 for the monomer container 96 are made in a single piece from a plastic material, for example by injection molding. The hollow cylinder 62 is limited on its lower side (bottom in FIG. 6) by a funnel shaped floor 91 that tapers steadily in the downward direction. This ensures that all of the monomer liquid can flow and / or be pushed out of the hollow cylinder 62. The pumping plunger 64 is formed by a hollow body made of a plastic material and is formed on the bottom surface 92 thereof as a negative image of the floor 91 of the hollow cylinder 62. The pumping plunger 64 is sealed with respect to the inner wall of the hollow cylinder 62 by a seal 93 and is supported on the hollow cylinder 62 as a support surface so that it is movable in the longitudinal direction (downward in FIG. 6).

  The junction 94 of the connector 70 for the monomer container 96 to the hollow cylinder 62 is provided on the jacket surface of the hollow cylinder 62 just below the lower surface 92 of the pumping plunger 64. The junction 94 is a conduit means for the monomer liquid, so that the junction 94 can be interpreted as part of a connection conduit 88, 94 for the monomer liquid having a hollow cylinder 62 disposed thereon. Form.

  A sieve 95 or filter 95 that can trap the fragments and portions of the opened monomer container 96 is disposed in the connector 70 for the monomer container 96. The monomer container 96 is an ampoule head 97 that can be folded and a glass ampoule 96 that has a neck that can be broken open so that the neck can be used to connect the ampoule head 97 to the body of the ampoule 96. Connect to. Due to the elasticity of the receptacle 71 for the monomer container 96 and due to the receptacle 71 being unfolded in the region of the neck, the head of the monomer container 96 is bent by bending the receptacle 71 with the monomer container 96 therein. 97 can be folded. By this means, the receptacle 71 having a suitable shape, in particular a shape that is unfolded in the region of the neck, forms an opening means 71 for opening the monomer container 96. Other opening means for cutting off the head 97 of the monomer container 96 can be implemented just as well.

  An inclined floor 98 that is inclined in the direction of the joint 94 is provided in the connection socket 68 under the sieve 95 and / or the filter 95. By this means, all the monomer liquid can flow from the monomer container 96 through the joint 94 to the hollow cylinder 62.

  The method according to the invention can be carried out, for example, by the apparatus according to FIGS. The device is placed by the base 60 on a table or on any other suitable level support. By twisting the elastic receptacle 71 by breaking and / or breaking the head 97 open, the monomer container 96 is opened. The monomer liquid from the monomer container 96 flows through the sieve 95 and / or the filter 95. Thereby, the fragment of the monomer container 96 is retained. The inclined floor surface 98 guides the monomer liquid to the hollow cylinder 62 through the joint portion 94. The empty internal space of the hollow cylinder 62 is completely filled with the monomer liquid. This is because the monomer container 96 contains more monomer liquid than can be taken up by the hollow cylinder 62. The contained air escapes through the joint 94. This is because the joint 94 is located at the uppermost position in the space bounded by the hollow cylinder 62 and the pumping plunger 64. In this context, the loop 90 is positioned clearly above the junction 94 and is also positioned above the level of the monomer liquid in the connector 70 so that the monomer liquid does not rise to this level in the absence of pressure. As a result, the monomer liquid cannot flow beyond the top of the loop 90.

  Thereafter, the clamp 65 is withdrawn from the apparatus. Thus, the pumping plunger is unlocked. Due to the mechanical tension of the compression spring 67, the pumping plunger 64 is then pushed completely into the hollow cylinder 62. By this means, the monomer liquid is transferred from the hollow cylinder 62 through the connecting conduit 88 to the internal space 74 of the cartridge 51 and / or pressed. The monomer liquid is pressed into the internal space 74 of the cartridge 51 through the filter 82. And then it rises and mixes with the cement powder stored in the internal space 74 of the cartridge 51.

  After the monomer liquid is filled into the internal space 74 of the cartridge 51, the mixing equipment 76 and / or the mixing rod 54 are pushed and pulled out by the handle portion 56 to manually mix the monomer liquid and cement powder. , Rotated. The cement dough and / or PMMA bone cement is then mixed. After mixing is complete, the mixing rod 54 is withdrawn from the interior space 74 of the cartridge 51 until a limit stop and folded to ensure that it does not interfere at a later time. If applicable, the locking mechanism of the prefabricated plunger 52 can be released. Thereafter, the cartridge 51 is unscrewed from the base 60 and a preformed tube (not shown) can be screwed onto the internal thread on the cartridge connector 86. Thereafter, the raw bone cement can be released from the interior space of the cartridge through the preform opening and the preform tube by pressing the preform plunger 52 inward. And raw bone cement can be applied.

  The features of the invention disclosed in the previous description and in the claims, figures, and exemplary embodiments can be essential to the implementation of the various embodiments of the invention, both alone and in any combination.

DESCRIPTION OF SYMBOLS 1,51 ... Cartridge 2,52 ... Pre-made plunger 3,53 ... Vacuum connector 4,54 ... Mixing rod 6,56 ... Handle part 8,58 ... Socket 10,60 ... Base 12,62 ... Hollow cylinder 14,64 ... Pumping plungers 16, 66 ... Housings for connecting conduit loops 18, 68 ... Connection sockets 20, 70 ... Monomer container connectors 21, 71 ... Monomer container / opening means elastic receptacles 22, 72 ... Lids 24, 74 ... cartridge inner space 26, 76 ... mixing blade / mixing equipment 28, 78 ... sterilization plunger 29, 79 ... seal 30, 80 ... sealing plunger 32, 82 ... powder impervious and liquid permeable filter 34, 84 ... Base connector with external thread 36, 86 ... Cartridge connector with internal thread 38, 8 8 ... Connection conduit 40, 90 ... Connection conduit loop 41, 91 ... Hollow cylindrical floor 42, 92 ... Lower surface of pumping plunger 43, 93 ... Seal 44, 94 ... Joint to hollow cylinder / connection conduit 45, 95 ... Sieve / filter 46, 96 ... Glass ampoule / monomer container 47, 97 ... Glass ampoule head / monomer container head 48, 98 ... Inclined floor of connector for monomer container 63 ... Screw cover 65 ... Lock mechanism / Clamp 67 ... Tensioned compression spring

Claims (26)

For mixing polymethylmethacrylate bone cement, and a device for storing the starting components of the bone cement, the monomer solution and cement powder as starting components before Symbol bone cement, and
A cartridge (1, 51) having an internal space (24, 74) for mixing said bone cement, which is closed on one side by a movable pre-made plunger (2, 52). ),
A monomer container (46, 96) for the monomer liquid such that the monomer container (46, 96) can be properly opened into the apparatus so that the monomer liquid flows from the monomer container (46, 96) to the apparatus. ) And / or connectors (20, 70) for attachment of monomer containers (46, 96) for monomer liquids,
A connecting conduit (38, 88) through which the monomer liquid can be led to the internal space (24, 74) of the cartridge (1, 51);
A device comprising:
A hollow cylinder (12, 62) is connected to the connecting conduit (38, 88), and the hollow cylinder (12, 62) is the monomer container (46, 96) or the monomer container (46, 96). Between the connector (20, 70) and the internal space (24, 74) of the cartridge (1, 51);
Thereby, a pumping plunger (14, 64) which can be displaced axially in the hollow cylinder (12, 62) is arranged in the hollow cylinder (12, 62),
Thereby, the monomer liquid can flow from the opened monomer container (46, 96) to the hollow cylinder (12, 62), and the connecting conduit (38, 88) is connected to the hollow cylinder (38, 88). 12, 62) are appropriately connected to the internal space (24, 74) of the cartridge (1, 51), and then the pumping plunger (14, 64) is activated by actuating the pumping plunger (14, 64). 64) is used to push the monomer liquid from the hollow cylinder (12, 62) through the connecting conduit (38, 88) to the internal space (24, 74) of the cartridge (1, 51). Can
A device characterized by that. A mixing facility (26, 76), which can be actuated from the outside, is arranged in the cartridge (1, 51), whereby the mixing facility (26, 76) is connected to the pre-made plunger (2, 52). characterized in that the guided through feedthrough into the interior of the cartridge (1, 51), can be created dynamic by the mixing rod which is supported as allowed movement of the support surface (4, 54) The apparatus according to claim 1. The pre-made plunger (2, 52) is impermeable to powder, thereby being permeable to gas and disposed within the pre-made plunger (2, 52). It characterized that you have a pore filter which is impermeable to, according to claim 1 or 2.   Device according to any one of the preceding claims, characterized in that the internal space (24, 74) of the cartridge (1, 51) contains the cement powder.   Between the connecting conduit (38, 88) and the internal space (24, 74) of the cartridge (1, 51), it is impermeable to the cement powder and is permeable to the monomer liquid. Device according to any one of claims 1 to 4, characterized in that a filter (32, 82) is arranged. The apparatus comprises a base (10, 60) at least a portion of the connecting conduit (38,88) is disposed therein, whereby said cartridge (1, 51) is detachably by Ji roots wherein connected to the base (10, 60), whereby, if applicable, in the cement powder impermeable, and the monomer liquid permeable filter (32, 82) is pre-Symbol base (10, 60) Device according to any one of the preceding claims, characterized in that it is arranged in a connection (34, 84) to the cartridge (1, 51). The hollow cylinder (12, 62) and the monomer container (46, 96) or the connector (20, 70) for mounting the hollow cylinder (12, 62) and the monomer container (46, 96) , characterized in that connected to the base (10, 60) at the solution discharge non methods, apparatus according to claim 6. The connector for attachment of the monomer container (46,96) or the monomer solution or the monomer container (46,96) (20,70), said hollow cylinder just below the previous SL pumping plunger (14, 64) Device according to any one of the preceding claims, characterized in that it terminates at (12, 62). Said device comprises opening means (21, 71) for opening said monomer container (46, 96) by which said monomer container (46, 96) can be opened inside a connecting device, thereby A sieve (45, 95) or filter (45, 95) arranged at the connection to the hollow cylinder (12, 62) in which a piece or piece of the opened monomer container (46, 96) can be held ) characterized that you have a device according to any one of claims 1-8.   10. A device according to any one of the preceding claims, characterized in that the monomer container (46, 96) is arranged above the connection to the hollow cylinder (12, 62). Said connecting conduit (38,44,88,94) is at the lowest point before Symbol hollow cylinder (12, 62) are connected to said hollow cylinder (12, 62), whereby said hollow cylinder (12 characterized that you have the pumping plunger (14, 64) arranged on the opposite side of 62), apparatus according to any one of claims 1 to 10. The hollow cylinder (12, 62) comprises a conical, hemispherical or any other downwardly tapered floor (41, 91) opposite the pumping plunger (14, 64); thus, a negative image of the surface (42, 92), the front Kiyuka (41,91) of the pumping plunger facing the floor (41,91) of said hollow cylinder (12, 62) (14, 64) The device according to claim 1, wherein the device is formed. Device according to any one of the preceding claims, characterized in that the pumping plunger (14, 64) can be pressed axially in the hollow cylinder (12, 62) by hand. .   14. The hollow cylinder (12, 62) according to any one of claims 1 to 13, characterized in that the hollow cylinder (12, 62) is transparent and comprises markings indicating the filling level of the liquid in the hollow cylinder (12, 62). The device described.   In order to press the monomer liquid from the hollow cylinder (12, 62) to the internal space (24, 74) of the cartridge (1, 51), the pumping plunger (14, 64) is moved to the hollow cylinder (12). 62), the hollow cylinder (12, 62) is provided with an internal thread, and the pumping plunger (14, 64) is provided with an external thread to be engaged. Item 15. The apparatus according to any one of Items 1 to 14.   The device comprises a tensioned compression spring (67) and a locking mechanism (65) so that the compression spring (67) and / or the pumping plunger (64) can be releasably locked. When the locking mechanism (65) is released by being locked by the mechanism (65), the compression spring (67) is pressed against the hollow cylinder (62) by the pumping plunger (64). Device according to any one of the preceding claims, characterized in that pressure is exerted on the pumping plunger (64) to the effect. The preformed plunger (2, 52) is released so that the preformed plunger (2, 52) can move axially in the internal space (24, 74) of the cartridge (1, 51). Connected to the cartridge (1, 51) by a possible snap-type device, whereby the snap-type device can be released manually by the action of an axial force, The apparatus according to claim 1.   The connecting conduit (38, 44, 88, 94) between the hollow cylinder (12, 62) and the internal space (24, 74) of the cartridge (1, 51) is an upward loop (40, 90). ), Whereby the uppermost position of the loop (40, 90) is the monomer container (46, 96) of the monomer container (46, 96) or to the hollow cylinder (12, 62) Device according to any one of the preceding claims, characterized in that it is above the joint (44, 94) of the connector (20, 70) for use.   19. The volume of the hollow cylinder (12, 62) is less than or equal to the amount of the monomer liquid in the monomer container (46, 96). The device described.   2. The internal space (24, 74) of the cartridge (1, 51) is connected to the connecting conduit (38, 88) in a liquid-permeable manner on the lower side. The apparatus of any one of -19. For mixing the bone cement, a method for mixing bone cement with an apparatus according to any one of 請 Motomeko 20, the following time step,
A) the step of opening the monomer container (46, 96);
B) The monomer liquid flows from the monomer container (46, 96) to the hollow cylinder (12, 62) so that the hollow cylinder (12, 62) is brought up one side by the pumping plunger (14, 64). Bordering steps,
C) The pumping plunger (14, 64) is pushed into the hollow cylinder (12, 62), so that the monomer liquid flows from the hollow cylinder (12, 62) and through the connecting conduit (38, 88). And pressed into the internal space (24, 74) of the cartridge (1, 51), whereby cement powder is located in the internal space (24, 74) of the cartridge (1, 51). Steps and
D) mixing the monomer liquid and the cement powder in the internal space (24, 74) of the cartridge (1, 51);
Including the method.   Once the pumping plunger (14, 64) has been pushed completely into the hollow cylinder (12, 62) or until the marking, the monomer liquid and the cement powder are in the internal space of the cartridge (1, 51). (24, 74), whereby the marking is a meter for the monomer liquid supplied to the internal space (24, 74) of the cartridge (1, 51). The method according to claim 21. By moving the mixing rod (4, 54) led to the internal space (24, 74) of the cartridge (1, 51) so that it can be rotated and displaced longitudinally by operating mixing facilities (26, 76), the monomer solution and the cement powder is mixed in the inner space (24, 74) by said mixing equipment (26, 76), whereby the pre-Symbol mixed damaged rod (4, 54), after said withdrawn from the interior space (24, 74) of the cartridge after mixing until limit stop (1, 51), said mixing rod (4, 54) has a predetermined The method according to claim 21 or 22, wherein the method is folded at a site. The monomer container (46, 96) is opened by actuating or actuating the opening means (21, 71), thereby being broken to be opened by the opening means (21, 71). It characterized that you have a 46,96) the method according to any one of claims 21 to 23. The pumping plunger (14, 64) is pushed into the hollow cylinder (12, 62) by an elastic spring element which is tensioned (67), whereby, before Symbol pumping plunger (14, 64) and / or said engage spring elements (67), characterized the first release child lock mechanism (65) is the method according to any one of claims 21 to 24.   The cartridge (1, 50) with raw cement dough is released from the connecting conduit (38, 44, 88, 94), hollow cylinder (12, 62), and monomer container (46, 96). And is supported so as to be axially movable in the cartridge (1, 51) and borders the internal space (24, 74) of the cartridge (1, 51) on one side. The said raw cement dough is pre-made from said internal space (24, 74) of said cartridge (1, 51) by advancing the pre-made plunger (2, 52) in contact. The method according to any one of 21 to 25.

Images