JP6050939B2 - Container and apparatus for holding the container - Google Patents

Description

  The present invention relates to a container for storing a liquid such as a reagent containing particles, or an apparatus capable of holding such a container, and more particularly to a container having a function of mixing reagents and an apparatus using the same.

  In general, the amount of reagent enclosed in the reagent container is sufficient to perform a large number of analyses. For this reason, when a concentration difference occurs in the reagent contained in the reagent container, there is a concern that the composition contained in the reagent used for each of the plurality of analyzes varies and affects the measurement result. Therefore, in the analysis method using such a reagent, it is necessary that the composition of the reagent used every time is constant.

  Here, in the analysis method using an antigen or antibody reaction, the analysis is generally performed using a reagent containing latex particles or magnetic particles in the reagent. These reagents are a mixture of particles and a solution. If the reagent is left for a long time, the particles in the reagent settle to the bottom surface of the reagent container with time.

  If the particles in the reagent settle, the particle concentration near the bottom surface of the reagent container is naturally high and the particle concentration near the reagent liquid surface is low. Because the analysis obtains the measurement result based on the numerical relationship between the number of particles and the analysis target, even if the reagent volume used in the analysis is constant, the same analysis can be performed if the number of particles contained in the reagent is different. There is a possibility that different measurement results may be obtained even for the target.

  Further, in the case of such a reagent, since the antigen and antibody are modified on the particle surface, the particles may aggregate when stacked by particle sedimentation. Aggregates of a plurality of particles lose the surface area of the particles as compared with the same number of single particles, which is undesirable in analysis because the number of measurement objects captured by the particles is reduced. Moreover, it is difficult to control the aggregation state to be constant, and as a result, the reliability of the analysis result is lowered.

  Therefore, when analyzing using such a reagent, it is necessary to disperse and mix the settled particles in the solution before aspiration. Furthermore, it is desirable that there is no aggregate of particles in the reagent.

  In general, as a method of dispersing and mixing the reagent containing particles, for example, a method of manually mixing the reagent by inversion before using the reagent, a method of dispersing the settled particles in the solution, or automatically There is a method of stirring the reagent with a stirring element that stirs the reagent.

  However, in the former inversion mixing, a reagent film may be formed at the suction port for sucking the reagent in the process of turning the container sideways or upside down. In the case of an analyzer that automatically detects the level of the reagent liquid and performs an aspiration operation, such a reagent film may cause a false detection of the liquid level of the reagent, resulting in reliable analysis results. May affect.

  In addition, in the latter method, in which the stirring element is inserted into the reagent and stirred, the reagent adheres to the stirring element and contamination between reagents is caused by stirring another reagent in that state (contamination between reagents). In addition, there remains a problem of reagent consumption (reagent removal) due to taking out the reagent with the stirrer element out of the reagent container.

  For example, Patent Documents 1 to 3 include techniques for the apparatus to automatically stir the reagent when using a reagent containing particles. Patent Document 1 describes an analyzer that includes a rotation mechanism that mounts a plurality of reagent containers, and stirs the reagents by rotating the reagent containers themselves.

  Moreover, there exists patent document 4 as an example which provides a special shape in a container in order to rotate a container and to mix an internal solution. Here, a shape is described in which a vertical wall is provided in a fin shape from the wall inside the container. Moreover, in patent document 5, the shape which provides the processus | protrusion which protruded incline in the container inside is described. Furthermore, Patent Document 6 describes a technique for mixing inside a probe at the time of reagent aspiration.

JP 2002-196006 A Special table 2010-518401 gazette Special table 2008-541054 gazette JP 2002-340908 A WO09 / 090989 JP-A-10-62437

  The mixing method by container rotation described in Patent Documents 1 to 3 requires a complicated mechanism for individually rotating reagent containers. Furthermore, since the rotational motion is transmitted to the reagent only by friction between the inner wall of the container and the reagent, the mixing efficiency is very poor. Furthermore, since only the rotational force is mainly applied to the reagent inside the reagent container, the performance of isolating and diffusing the aggregated particles is low.

  Further, in a container having a protruding shape as described in Patent Documents 4 and 5, when the boundary between the reagent and air inside the reagent container is stirred by the protrusion, the reagent liquid surface may be bubbled. Such foaming may affect the variation of the reagent dispensing amount, and affects the reliability of the analysis result.

  Furthermore, in the case of mixing inside the probe described in Patent Document 6, mixing of the reagent is impossible unless the probe is inserted into the reagent container from the outside, and there are problems such as contamination between reagents and taking out of the reagent. It cannot be solved. Furthermore, if mixing is performed at the time of dispensing, it is necessary to suck a certain amount of particles that have settled to the bottom in the reagent container.

  In view of the above, the present invention makes it possible to equalize the concentration of the reagent before use in the analysis in the analysis using a reagent that causes non-uniformity in the reagent stored by leaving it for a long time, etc. It is an object of the present invention to provide a reagent container that does not cause problems such as contamination between reagents and removal of reagents.

  Furthermore, an object of the present invention is to provide an apparatus that uses the above-described reagent container and can make the reagent concentration in the reagent container uniform before dispensing.

  In order to achieve the above object, the features of the present invention are as follows. That is, a liquid storage unit that stores liquid, a pump unit that sucks the liquid from the liquid storage unit and then discharges the liquid again to the liquid storage unit, and a flow path that connects the pump unit and the liquid storage unit The liquid storage part, the pump part, and the flow path are integrated into a container.

  By configuring the container with such a configuration, it is possible to effectively stir and mix the liquid containing particles without bringing a stirring element into the container from the outside.

  Furthermore, another feature of the present invention is an apparatus capable of handling the container as described above.

  Further features of the present invention will become apparent from the embodiments of the invention described below.

  According to the present invention, since it is not necessary to insert a stirring element into the reagent container from the outside, it is possible to achieve a uniform reagent concentration without causing contamination between reagents or taking out the reagent. Further, since the pump is formed integrally with the container, it is not necessary to provide a special pump or the like on the apparatus side in order to make the reagent concentration uniform, and the apparatus cost can be reduced.

  Furthermore, since a change in speed and pressure is given to the reagent in the process of homogenizing the reagent, there is an effect of isolating and diffusing the aggregated particles.

  Furthermore, in the apparatus combination, the pump can be operated by moving the mechanism in which the reagent container is arranged, and the apparatus can be simply configured.

The external view of one Example of the reagent container of this invention. Sectional drawing of one Example of a reagent container. 4 shows another embodiment of the reagent container of the present invention. Sectional drawing of the other Example of a reagent container. An example of the apparatus using the reagent container of this invention. Operation | movement explanatory drawing of the pump part by apparatus mounting. Another embodiment of the apparatus using the reagent container of the present invention (pump operation explanation 1). Another embodiment of the apparatus using the reagent container of the present invention (pump operation explanation 2). The reagent container in the other pump part structure of this invention. Sectional drawing of the reagent container in the other pump part structure of this invention.

  Embodiments of the present invention will be described below with reference to the drawings. Since the configuration of the apparatus and mechanism not related to the present invention need not be particularly limited, detailed description will be omitted.

  FIG. 1 shows an external view of an embodiment of a reagent container according to the present invention. The reagent container 101 includes a reagent storage unit 102 in which a reagent is filled and stored, and a pump unit having a syringe pump 103 connected from the reagent storage unit 102 via the flow path 1. One suction / discharge port 2 serving as a suction port for sucking the reagent from the reagent storage unit 102 into the flow path 1 by the syringe pump 103 and a discharge port for discharging the sucked reagent back to the reagent storage unit 102 is provided. . A plurality of suction / discharge ports 2 may be arranged, or a reagent suction port and a discharge port may be provided individually.

  Details of the structure of the embodiment shown in FIG. 1 will be described with reference to a sectional view 2 of the reagent container 101. FIG.

  The syringe pump 103 includes a plunger 4 that changes the volume of the pump volume 12, a push-down portion 3 that acts from the outside to push down the plunger 4, a plunger guide portion 7 that holds other members of the plunger 4, and a gap between components Is composed of a seal 5 for hermetically sealing, a spring 6 for pushing up the depressed plunger, and a fixing screw 8 for limiting the rising height of the plunger 4 and fixing other components. Here, the spring 6 that pushes up the plunger 4 may be another elastic body, for example, a member such as rubber.

  The reagent storage unit 102 includes a reagent container body 9 and a cap 10 which are reagent container bodies. The reagent container body 9 in FIG. 2 is a single block-shaped part, but may be a combination of a thin-walled structural part by molding and a divided part.

  FIG. 3 shows an external view of another embodiment, and FIG. 4 shows a cross-sectional view thereof.

  FIG. 3 shows an example in which another reagent storage unit 104 that accommodates a reagent that does not require stirring and mixing is arranged in addition to the reagent storage unit 102 that performs stirring and mixing. Further, in the embodiment of FIGS. 3 and 4, the cross-sectional area in the middle of the flow path 1 through which the reagent moves is increased by the suction and discharge of the reagent from the reagent storage unit 102. As a method of changing the cross-sectional area of the flow channel 1, as shown in FIGS. 3 and 4, the cross-sectional area of a part of the reagent moving part may be increased. Any method of decreasing may be used. In any case, it is desirable that the cross-sectional area changes continuously. By providing the flow path 1 having a different cross-sectional area depending on the position, it is possible to apply a speed change or a pressure change to the particles when the reagent is stirred and mixed by the syringe pump 103, and the particles form aggregates. Can also be isolated.

  In the embodiment shown in FIGS. 1 to 4, a suction / discharge port 2 for sucking and discharging a reagent from the reagent storage unit 102 is provided at the bottom of the reagent storage unit 102, and the flow path 1 is located near the bottom surface of the reagent container 102. It is arranged. Thereby, for example, in the case of a reagent containing particles, a reagent flow that makes the particles uniform in the reagent container can be formed, and efficient stirring can be realized. Furthermore, if a reagent discharge port is provided so that the flow direction of the reagent from the reagent discharge port is upward, a reagent flow from the vicinity of the bottom surface of the reagent container toward the opening can be formed. Mixing can be performed. Since the reagent containing particles settled on the bottom of the reagent storage unit 102 can be sucked and discharged, the aggregated reagent can be preferentially isolated. Further, if the suction port is provided near the bottom surface, the reagent can be stirred even when the remaining amount of the reagent is reduced.

  Furthermore, if the difference in height between the suction / discharge port 2 and the flow path 1 is reduced, the reagent can be smoothly introduced into the flow path 1.

  A lower slope 11 inclined in the direction of the flow path 1 may be provided on the bottom surface of the reagent storage unit 102. By providing the low-surface slope 11, even when the remaining amount of the reagent is reduced, the reagent is accumulated in the vicinity of the suction / discharge port 2, so that the structure can be stirred. In this embodiment, the slope is formed by the low slope 11, but a corner R shape may be used.

  In this embodiment, the direction of the discharge port of the reagent is formed so as to be perpendicular to the wall surface of the reagent storage unit 102. For example, the direction of the discharge port is set so as to discharge in the tangential direction of the reagent storage unit 102. If designed, stirring and mixing using a swirl flow are possible.

  Next, the syringe pump operation of the reagent container 101 according to the present embodiment will be described with reference to FIG.

  This operation description is made from the state in which the reagent storage unit 102, the flow path 1 and the pump volume 12 are filled with the reagent. Here, in the process of filling the reagent storage unit 102, the flow path 1 and the pump volume 12 with the reagent, the plunger 4 is lowered when the reagent storage unit 102 is filled with the reagent to minimize the pump volume 12. Or after the reagent storage unit 102 is filled with the reagent, the push-down unit 3 is lowered and raised and the syringe pump 103 is operated. Further, these processes may be performed manually before using the reagent container 101, or may be performed automatically after the reagent container is mounted on the apparatus.

  The operation of the syringe pump 103 is performed by moving the push-down unit 3 up and down. In a state where the pressing portion 3 is not pressed down by an external force, the plunger 4 is raised to the maximum height position by the repulsive force of the spring 6. In the present embodiment, the position where the upper surface of the different diameter portion of the plunger 4 contacts the fixing screw 8 is the maximum height.

  When the push-down portion 3 is pushed down in a state where the plunger 4 can be lowered, the plunger 4 is lowered. The limit of the descending amount may be either the position where the plunger 4 stops mechanically or the height in the middle.

  By the lowering of the plunger 4, the reagent previously sucked into the pump volume 12 and the flow path 1 is discharged from the suction / discharge port 2 to the reagent storage unit 102. A flow is formed in the reagent inside the reagent storage unit 102 by the discharged reagent, and the reagent in the reagent storage unit 102 is stirred and mixed.

  When the external force that has pushed down the push-down portion 3 is released, the plunger 4 rises due to the repulsive force of the spring 6, and the reagent flows from the suction / discharge port 2 of the reagent storage portion 102 as the pump volume 12 increases. Sucked inside. Thereafter, by repeating the above operation, the same reagent can be continuously stirred and mixed. Here, as in the embodiment of the present invention, when the reagent is aspirated / discharged using the flow path 1, a flow rate change and a pressure change occur with respect to the aspirated / discharged reagent. In particular, the inside of the flow path 1 that is the flow in the tube is in a low pressure state with respect to the reagent in the reagent storage unit 102 during suction, and is in a pressurized state during discharge. Furthermore, when the reagent moves between the reagent storage section 102 having a large cross-sectional area and the flow path 1 having a small cross-sectional area, a change in flow velocity and a change in streamline direction occur with respect to the reagent.

  By applying such pressure fluctuations, flow velocities, and changes in streamline direction to the reagent, for example, when the reagent contains particles and the particles are aggregated, the aggregated particles It becomes the effect | action which isolates.

  In the embodiment shown in FIGS. 3 and 4, the cross-sectional area of the flow path 1 is changed. In this case, a multistage flow rate change can be given to the reagent moving through the flow path 1 from the reagent storage unit 102 by the suction and discharge operations. That is, (1) a step in which the reagent is taken into the suction port of the flow channel 1 from the reagent storage unit 102 due to the negative pressure of the syringe pump, and (2) a cross-sectional area of the flow channel that is drawn from the suction port of the flow channel 1 In each step of (3) the step of being taken up to the changing portion, (3) the step of being pushed out to the discharge port when the syringe pump 103 is pressurized, and (4) the step of being discharged from the discharge port to the reagent storage unit 102, It is possible to change the flow rate of the reagent. If such a flow path 1 is used, the flow rate and pressure changes are generated in multiple stages in the reagent that is aspirated and discharged inside the flow path 1, so that the effect of isolating the aggregated particles is further improved.

  It should be noted that the amount of reagent sucked by the syringe pump 103 from the reagent storage unit 102 is desirably smaller than the amount of reagent filled and stored in the reagent storage unit. If the amount of reagent to be sucked is larger than the amount of reagent in the reagent storage unit 102, air is sucked into the flow path or the reagent is discharged into the empty reagent storage unit 102. In this case, air is entrained in the aspirated and discharged reagent with stirring by the syringe pump 103, and therefore the reagent bubbles in the reagent storage unit 102 depending on the composition of the reagent. When foaming occurs in the reagent, problems such as erroneous detection of the foam surface as the liquid level occur when the apparatus performs liquid level detection.

  An embodiment in which the reagent container 101 according to the present invention is combined with an apparatus is shown in FIGS. In addition, the mechanism etc. which are not directly related to this invention are abbreviate | omitted.

  The operation of the embodiment of FIG. 5 will be briefly described with reference to FIG. FIG. 5 shows an example in which a plurality of reagent containers 101 are arranged on the reagent disk 13 and an up-and-down mechanism 14 for operating the syringe pump 103 of the reagent container 101 is arranged.

  In the reagent container 101, the reagent disk 13 is rotated by the operation of the disk rotating mechanism 16 in accordance with the purpose such as movement of the reagent to the sorting position. After the rotational movement is stopped, the contact portion 15 is lowered with respect to the reagent container 101 located below the vertical mechanism 14, and the push-down portion 3 of the reagent container 101 is pushed down. As a result, the reagent in the flow path is pushed out to the reagent storage unit 102, and a reagent flow is generated in the reagent storage unit 102. Thereafter, when the contact portion 15 is lifted away from the push-down portion 3, the syringe pump 103 is raised, and the reagent is taken into the flow path from the reagent storage portion 102. After that, by repeating the vertical movement of the push-down unit 3 a predetermined number of times as necessary, the reagent is aspirated and discharged inside the reagent container 101, and the reagent is stirred and mixed.

  In the embodiment of FIG. 5, the apparatus is shown as an embodiment in which the stirring and mixing action is performed on one reagent container 101 at a time, but for example, if the contact portion 15 acting on a plurality of reagent containers is prepared, A plurality of reagent containers can be stirred and mixed simultaneously.

  Further, for example, if the lowering operation speed of the contact unit 15 by the up-and-down mechanism 14 is changed, the reagent discharge speed can be changed, and if the lowering amount is changed according to the remaining amount of the reagent in the reagent storage unit 102, By changing the amount of the reagent used for stirring, it is possible to achieve reagent stirring without foaming. For example, for a reagent container containing a reagent that tends to bubble or a reagent container with a small amount of remaining reagent, the lowering amount of the contact portion 15 is decreased or the lowering speed of the contact portion 15 is decreased. The extrusion speed of extrusion from the path 1 to the reagent storage unit 102 can be made slow, and the amount of extruded reagent can be reduced. Thereby, it can avoid that the reagent liquid surface foams because the extruded reagent vigorously ejects from the ejection port.

  FIG. 7 and FIG. 8 show an embodiment of a device combination according to another configuration.

  In this embodiment, a plurality of reagent containers are placed on the circumference of the reagent disk 13 that rotates, and the push-down portion 3 of the syringe pump 103 for stirring and mixing the reagent is provided on the outer circumference of the reagent container. Also, the direction of the reagent container is arranged so that there is a reagent suction port inside. On the side wall of the reagent disk 13, there is provided a roller 17 that can rotate in a positional relationship so as to contact the pressing portion 3 of the reagent container 101 and lower the pressing portion 3.

  When the reagent disk 13 in which the reagent container 101 is installed rotates and moves, the pressing portion 3 of the reagent container 101 positioned below the roller 17 at the position shown in FIG. As shown in FIG. 8, the push-down unit 3 is released. Since the roller 17 protrudes and is disposed on the reagent disk 13, a notch 18 may be provided in the reagent disk 13 according to the number of the rollers 17 in order to remove the reagent disk 13.

  According to the present embodiment, there is no need to prepare an individual movable mechanism for operating the syringe pump 103 as shown in FIG. 5, and the syringe container 103 is rotated by the rotation of the reagent disk 13, whereby the syringe pump 103. Can be operated. According to this, since the apparatus has a simple configuration and the reagent can be stirred and mixed each time the reagent disk is driven, analysis using a uniform reagent is always possible. If the position where the roller 17 is provided is positioned at least immediately before the reagent dispensing position, a reagent with higher uniformity can be used during reagent dispensing.

  In this embodiment, the reagent container 13 is arranged on the circumference of the reagent container 101, and the reagent disk is rotated to move and equalize the reagent. Even in this form, it is possible to achieve the same effect. For example, when the reagent container 101 is provided with a reagent container arranged in a straight line, and the reagent is moved linearly during processing such as reagent dispensing, a roller is provided at a predetermined position on the inner wall of the reagent container. As the reagent moves, the pressing unit 3 may be configured so that the roller can be pressed down. In any case, a roller 17 that is in contact with the push-down unit 3 may be arranged on the movement path of the reagent container 101 and on the movement track of the push-down unit 3. The same effect can be obtained when the pressing portion 3 itself is a member such as a roller, and a fixing member that contacts the pressing portion 3 formed of a roller is provided on the inner wall of the reagent storage.

  Another embodiment of the reagent container structure according to the present invention is shown in FIG. 9, and a sectional view thereof is shown in FIG.

  In the embodiment shown in FIG. 9, in order to simplify the configuration of the syringe pump 103, a hollow dome 19 is provided in the reagent container 101, and the reagent is aspirated and discharged by changing the volume thereof. Further, the reagent container 101 of the embodiment of FIG. 9 has a configuration divided into a container part 105 and a pump part 106.

  The structure of FIG. 9 will be described with reference to FIG. In the embodiment of FIG. 9, the reagent container 101 is divided into a container part 105 and a pump part 106, and they are assembled. Here, although not described in detail, the flow path 1 from the suction / discharge port 2 of the reagent storage unit 102 and the flow path 1 ′ of the pump unit 106 are connected in a sealable structure. In this way, by dividing the container part and the pump part into a separable structure, the pump part can be used repeatedly by assembling the pump part in another container part after the container part is empty. Has the advantage of being.

  The dome 19 of the pump unit 106 is made of a different material or a thin film different from other parts of the reagent container 101 so that it can be deformed by pressing.

  Further, when the inside of the dome 19 is hollow, when the dome 19 is crushed and then it is desired to restore the original shape, the elastic body 20 is disposed inside the dome 19 as shown in FIG. Since the elastic body 20 needs to change in volume similarly according to the volume change of the dome 19, for example, an open-cell foam material such as foamed silicon rubber is used.

  Further, in the present embodiment of FIG. 9, the hemispherical dome 19 is used. However, if the volume is changed by pressing, a collapsible bellows shape or other shapes may be used without changing to a hemispherical shape.

  According to the above configuration, as with the reagent container 101 of FIGS. 1 to 4, the suction and discharge of the reagent from the reagent storage unit 102 can be realized by the volume change of the dome 19.

  Moreover, although the reagent container 101 of the Example shown in FIGS. 1-10 makes the pressing direction of the syringe pump 103 and the pump part 106 the up-down direction, for example, if the pressing part 3 of the syringe pump 103 is moved to a side surface. The horizontal direction may be used, and there is no need to limit the vertical direction.

DESCRIPTION OF SYMBOLS 1 Flow path 2 Suction / discharge port 3 Push-down part 4 Plunger 5 Seal 6 Spring 7 Plunger guide part 8 Fixing screw 9 Reagent container body 10 Cap 11 Bottom slope 12 Pump volume 13 Reagent disk 14 Vertical mechanism 15 Contact part 16 Disk rotation mechanism 17 Roller 18 Notch 19 Dome 20 Elastic body 101 Reagent container 102 Reagent storage part 103 Syringe pump 104 Other reagent storage part 105 Container part 106 Pump part

Claims (15)

A liquid storage unit that stores a liquid used for analysis, a pump unit that is disposed outside the liquid storage unit and includes a push-down unit that can change the volume or volume by receiving an external force, and the pump unit and the pump unit A container container that can accommodate a plurality of containers integrated with a flow path connecting the vicinity of the bottom surface of the liquid storage unit; and
A contact mechanism that applies an external force that causes a volume change in contact with the depressed portion, and
By controlling the contact state of the contact mechanism with respect to the push-down portion of the container containing the liquid to be stirred, the liquid in the liquid storage portion is sucked and discharged between the liquid storage portion and the flow path. A stirrer. The apparatus of claim 1.
The contact mechanism is a push bar or a roller for applying a pressing force to the pump unit. The apparatus of claim 1.
The container storage is arranged and held a plurality of containers,
An apparatus comprising transfer means for horizontally transferring a container in the container storage. The apparatus of claim 3.
The container storage has a side wall,
The contact mechanism is provided at a position that engages with the pump portion inside the side wall,
The apparatus is characterized in that the contact mechanism applies an external force to the pump unit by transferring the container in a container storage. The apparatus of claim 1.
An elevating mechanism for elevating and lowering the contact mechanism relative to the push-down portion;
An apparatus having a control unit for controlling the descending operation speed or the descending amount. The apparatus of claim 5.
The control unit is a device that controls a descent operation speed or a descent amount according to a liquid amount or a liquid type in the liquid storage unit. A liquid storage section for storing a liquid used for analysis;
A pump unit that is disposed outside the liquid storage unit and includes a push-down unit capable of changing the volume by receiving an external force; and
A flow path connecting the pump unit and the vicinity of the bottom surface of the liquid storage unit,
The liquid storage unit, the pump unit, and the flow path are configured as a single unit,
A container that agitates the liquid in the liquid storage unit by sucking and discharging the liquid between the storage unit and the flow path by changing the volume of the push-down unit. The container according to claim 7,
A suction port for sucking the liquid in the liquid storage portion into the flow path;
A discharge port for discharging the sucked liquid from the flow path into the liquid storage unit,
The suction port and the discharge port suck and discharge liquid from below the liquid surface of the liquid storage unit. The container according to claim 7,
The container characterized in that a cross-sectional area of the flow path is smaller than a cross-sectional area of the liquid storage portion. The container according to claim 7,
A container characterized in that the cross-sectional area of the flow path changes continuously. The container of claim 8 ,
The discharge port discharges a reagent in a direction parallel to a tangent to a side wall of the liquid storage unit. The container of claim 8 ,
The container, wherein the suction port and the discharge port are the same opening. The container according to any one of claims 7 to 11,
The container contains a liquid containing particles. The container according to claim 7,
The said pump part is individually provided for every said liquid storage part, The container characterized by the above-mentioned. The container of claim 14,
The said pump part is provided with either a syringe pump, an elastic body dome, or a bellows structure, The container characterized by the above-mentioned.