JP5907979B2 - 補助チャネルおよびバイパス・チャネルを含むマイクロ流体デバイス - Google Patents

補助チャネルおよびバイパス・チャネルを含むマイクロ流体デバイス Download PDF

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JP5907979B2
JP5907979B2 JP2013535534A JP2013535534A JP5907979B2 JP 5907979 B2 JP5907979 B2 JP 5907979B2 JP 2013535534 A JP2013535534 A JP 2013535534A JP 2013535534 A JP2013535534 A JP 2013535534A JP 5907979 B2 JP5907979 B2 JP 5907979B2
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reagent
channel
flow
microfluidic device
auxiliary channel
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Japanese (ja)
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JP2013545095A (ja
Inventor
ドラマルシュ、エマニュエル
ジェルヴェ、リュク
ヒッツブレック、マルティーナ
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International Business Machines Corp
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International Business Machines Corp
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/32—Injector mixers wherein the additional components are added in a by-pass of the main flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2013535534A 2010-10-28 2011-08-03 補助チャネルおよびバイパス・チャネルを含むマイクロ流体デバイス Active JP5907979B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10189178 2010-10-28
EP10189178.6 2010-10-28
PCT/IB2011/053456 WO2012056334A1 (fr) 2010-10-28 2011-08-03 Dispositif microfluidique comprenant des canaux auxiliaires et de dérivation

Publications (2)

Publication Number Publication Date
JP2013545095A JP2013545095A (ja) 2013-12-19
JP5907979B2 true JP5907979B2 (ja) 2016-04-26

Family

ID=44583221

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013535534A Active JP5907979B2 (ja) 2010-10-28 2011-08-03 補助チャネルおよびバイパス・チャネルを含むマイクロ流体デバイス

Country Status (6)

Country Link
US (1) US9421540B2 (fr)
JP (1) JP5907979B2 (fr)
CN (1) CN103180047A (fr)
DE (1) DE112011102770B4 (fr)
GB (1) GB2499147B (fr)
WO (1) WO2012056334A1 (fr)

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GB2528930A (en) * 2014-08-05 2016-02-10 Palintest Ltd Water sample analysis kit
US10732189B2 (en) 2015-01-14 2020-08-04 Bio-Rad Europe Gmbh Blood analysis systems and methods
EP3247998B1 (fr) * 2015-01-21 2021-09-22 SBT Instruments A/S Dispositif d'analyse de particules microfluidiques
WO2016118949A1 (fr) * 2015-01-23 2016-07-28 Neofluidics Llc Plaque à puits basée sur une plateforme de dilution en série microfluidique faisant appel à une phase immiscible exempte d'huile entraînée par pipettes manuelles ou électroniques
CN107209183B (zh) 2015-01-23 2019-09-24 生物辐射实验室股份有限公司 免疫印迹系统和方法
EP3461559A1 (fr) * 2015-06-11 2019-04-03 Neofluidics LLC Plaque de puits entraînée par pipette manuelle ou électronique pour le stockage de nano-litres de gouttelettes et procédés d'utilisation associés
JP6598361B2 (ja) * 2015-09-10 2019-10-30 国立大学法人東北大学 検出装置、及び、検出方法
EP3263215B1 (fr) * 2016-06-30 2021-04-28 ThinXXS Microtechnology AG Dispositif comprenant un cellule comprenant un dispositif de stockage de reactif
CN106334488A (zh) * 2016-11-01 2017-01-18 海南大学 一种高效主动式微流体混合器和混合方法
JP6433473B2 (ja) 2016-11-04 2018-12-05 シスメックス株式会社 液体封入カートリッジ、液体封入カートリッジの製造方法および送液方法
WO2018200896A1 (fr) 2017-04-28 2018-11-01 Neofluidics, Llc Dispositifs fluidiques à puits de réaction, et utilisations associés
US10697986B2 (en) 2017-06-23 2020-06-30 International Business Machines Corporation Microfluidic device with programmable verification features
US10556233B2 (en) * 2017-06-23 2020-02-11 International Business Machines Corporation Microfluidic device with multi-level, programmable microfluidic node
CA3072328A1 (fr) 2017-08-09 2019-02-14 Neofluidics, Llc Dispositifs et procedes pour essai biologique
JP7256198B2 (ja) 2017-11-10 2023-04-11 ネオフルーイディクス，リミティド ライアビリティ カンパニー 液滴操作のための統合された流体回路およびデバイスならびにその方法
CN107843729A (zh) * 2018-01-03 2018-03-27 洪海裕 过敏原微流体芯片检测仪
NL2023366B1 (en) * 2019-02-08 2020-08-19 Illumina Inc Methods and devices for mixing in a microfluidic system
US11524292B2 (en) * 2019-02-21 2022-12-13 International Business Machines Corporation Programmable hydraulic resistor array for microfluidic chips

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Also Published As

Publication number Publication date
JP2013545095A (ja) 2013-12-19
GB201308641D0 (en) 2013-06-19
GB2499147B (en) 2015-06-03
DE112011102770B4 (de) 2014-11-20
GB2499147A (en) 2013-08-07
US20130337578A1 (en) 2013-12-19
US9421540B2 (en) 2016-08-23
CN103180047A (zh) 2013-06-26
DE112011102770T5 (de) 2013-07-18
WO2012056334A1 (fr) 2012-05-03

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