JP5903102B2 - 用量送達装置 - Google Patents

用量送達装置 Download PDF

Info

Publication number
JP5903102B2
JP5903102B2 JP2013529549A JP2013529549A JP5903102B2 JP 5903102 B2 JP5903102 B2 JP 5903102B2 JP 2013529549 A JP2013529549 A JP 2013529549A JP 2013529549 A JP2013529549 A JP 2013529549A JP 5903102 B2 JP5903102 B2 JP 5903102B2
Authority
JP
Japan
Prior art keywords
dose
driver
gear member
dose setting
screw
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2013529549A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013537819A (ja
JP2013537819A5 (enExample
Inventor
クラウス・スミット・メラー
Original Assignee
イーライ リリー アンド カンパニー
イーライ リリー アンド カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イーライ リリー アンド カンパニー, イーライ リリー アンド カンパニー filed Critical イーライ リリー アンド カンパニー
Publication of JP2013537819A publication Critical patent/JP2013537819A/ja
Publication of JP2013537819A5 publication Critical patent/JP2013537819A5/ja
Application granted granted Critical
Publication of JP5903102B2 publication Critical patent/JP5903102B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2013529549A 2010-09-24 2011-09-23 用量送達装置 Active JP5903102B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201000872 2010-09-24
DKPA201000872 2010-09-24
PCT/DK2011/000103 WO2012037938A1 (en) 2010-09-24 2011-09-23 A gearing mechanism for a dose delivery device

Publications (3)

Publication Number Publication Date
JP2013537819A JP2013537819A (ja) 2013-10-07
JP2013537819A5 JP2013537819A5 (enExample) 2015-12-17
JP5903102B2 true JP5903102B2 (ja) 2016-04-13

Family

ID=44883028

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013529549A Active JP5903102B2 (ja) 2010-09-24 2011-09-23 用量送達装置

Country Status (14)

Country Link
US (2) US8864721B2 (enExample)
EP (1) EP2618872B1 (enExample)
JP (1) JP5903102B2 (enExample)
KR (1) KR101493626B1 (enExample)
CN (1) CN103189084B (enExample)
AU (1) AU2011304788B2 (enExample)
BR (1) BR112013006410B1 (enExample)
CA (1) CA2813007C (enExample)
DK (1) DK2618872T3 (enExample)
EA (1) EA024223B1 (enExample)
MX (1) MX2013003340A (enExample)
PL (1) PL2618872T3 (enExample)
UA (1) UA109665C2 (enExample)
WO (1) WO2012037938A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120283652A1 (en) * 2009-09-30 2012-11-08 Sanofi-Aventis Deutschland Gmbh Assembly and Piston Rod for a Drug Delivery Device
JP6057991B2 (ja) * 2011-06-17 2017-01-11 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス用カートリッジ・ホルダ・アセンブリ
USD742506S1 (en) * 2011-06-27 2015-11-03 Ferring B.V. Medicine applicator
EP2644217A1 (de) * 2012-03-30 2013-10-02 TecPharma Licensing AG Injektionsvorrichtung mit Dosisanzeige und Federantrieb
CN104349806B (zh) * 2012-03-30 2017-12-26 特克法马许可公司 带有可相对于壳体移动的剂量指示元件的注射装置
EP2644218B2 (de) * 2012-03-30 2022-11-02 Tecpharma Licensing AG Injektionsvorrichtung mit Dosisanzeige und Federantrieb
AU349333S (en) * 2012-07-05 2013-06-20 Sanofi Aventis Deutschland Injection device
CN104736189A (zh) * 2012-10-23 2015-06-24 赛诺菲-安万特德国有限公司 在药物输送装置中使用的计数系统
US10220152B2 (en) 2013-03-14 2019-03-05 Norton Healthcare Limited Dispensing mechanism for a medical device
MX2015012900A (es) * 2013-03-14 2016-04-04 Norton Healthcare Ltd Mecanismo de dispensacion para un dispositivo medico.
GB2511806A (en) 2013-03-14 2014-09-17 Norton Healthcare Ltd Dispensing mechanism for a medical device
EP2968787B1 (en) * 2013-03-14 2020-04-29 Norton Healthcare Limited Dispensing mechanism for a medical device
HK1222146A1 (zh) * 2013-09-03 2017-06-23 Sanofi 用於药物传送装置的机构和包括该机构的药物传送装置
GB201318817D0 (en) * 2013-10-24 2013-12-11 Owen Mumford Ltd Injection Devices
JP6815198B2 (ja) * 2013-11-22 2021-01-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 一方向カップリングを有する薬物送達デバイス
MA39919A (fr) 2014-06-06 2015-12-10 Lilly Co Eli Extrémité rotative de mécanisme de rétroaction de dose
USD752210S1 (en) * 2014-08-27 2016-03-22 Merck Sharp & Dohme Corp. Medical injector pen
USD773646S1 (en) * 2014-08-27 2016-12-06 Merck Sharp & Dohme Corp Medical injector pen
USD777907S1 (en) * 2014-08-27 2017-01-31 Merck Sharp & Dohme Corp. Medical injector pen
CA2969349A1 (en) 2015-01-16 2016-07-21 Eli Lilly And Company Injection device with end of dose mechanism
JP6840092B2 (ja) * 2015-07-01 2021-03-10 ノボ・ノルデイスク・エー／エス 薬剤送達装置を組み立てる方法およびその方法により形成される薬剤送達装置
USD850613S1 (en) * 2016-09-09 2019-06-04 Sanofi-Aventis Deutschland Gmbh Drug delivery device
CN107648704B (zh) * 2016-07-26 2022-02-15 广东东阳光药业有限公司 一种注射器用传动结构及注射器
DE102018108701A1 (de) * 2018-04-12 2019-10-17 Gerhard Brugger System mit einem Dosierspender für das Austragen von pastösem oder viskosem Material
CN112805049B (zh) * 2018-09-08 2023-01-03 榭利工程塑料有限公司 注射装置
CN109078240B (zh) * 2018-09-30 2024-05-14 江苏德尔福医疗器械有限公司 带有剂量反馈装置的一次性注射笔
RU2729442C1 (ru) * 2019-10-23 2020-08-06 Общество с ограниченной ответственностью "НЭКСТ БИО" Устройство для доставки лекарственного средства
GB2604096B (en) * 2021-02-09 2023-03-15 Shaily Uk Ltd Dose delivery device with gearing
AU2023207323B2 (en) 2022-01-14 2025-09-25 Phillips-Medisize A/S Dose delivery device with modified decoupling clutch
PL444242A1 (pl) * 2023-03-28 2024-09-30 Nemera Szczecin Spółka Z Ograniczoną Odpowiedzialnością Urządzenie do wstrzykiwania leku

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3645245C2 (de) 1986-11-14 1994-01-27 Haselmeier Wilhelm Fa Injektionsgerät
DK166948B1 (da) 1988-02-10 1993-08-09 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule
US5279585A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Medication delivery pen having improved dose delivery features
US5391157A (en) 1992-10-20 1995-02-21 Eli Lilly And Company End of dose indicator
GB9226423D0 (en) 1992-12-18 1993-02-10 Sams Bernard Incrementing mechanisms
US5725508A (en) 1994-06-22 1998-03-10 Becton Dickinson And Company Quick connect medication delivery pen
NZ302558A (en) 1995-03-07 1999-11-29 Lilly Co Eli Dispensing apparatus with a medication cartridge with a manually adjustable metering mechanism
US5688251A (en) 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
US5921966A (en) 1997-08-11 1999-07-13 Becton Dickinson And Company Medication delivery pen having an improved clutch assembly
KR100574630B1 (ko) 1998-01-30 2006-04-27 노보 노르디스크 에이/에스 주입 주사기
US6221053B1 (en) 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
JP4283545B2 (ja) 2001-05-16 2009-06-24 イーライ リリー アンド カンパニー リセット簡易化式駆動アセンブリー付きの薬物注射装置
GB0205485D0 (en) 2002-03-08 2002-04-24 Dca Design Int Ltd Improvements in and relating to a medicament delivery service
US6945961B2 (en) 2002-07-10 2005-09-20 Novo Nordisk A/S Injection device
DE10237258B4 (de) 2002-08-14 2006-09-21 Tecpharma Licensing Ag Injektionsvorrichtung
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
EP2210634A1 (en) 2009-01-22 2010-07-28 Sanofi-Aventis Deutschland GmbH Drug delivery device dose setting mechanism
GB0304824D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
SI1656170T1 (sl) 2003-08-12 2019-05-31 Eli Lilly And Company Oprema za izdajanje zdravil s trojnim vijačnim navojem za mehanski pospešek
DE20317377U1 (de) 2003-11-03 2005-03-17 B D Medico S A R L Injektionsgerät
DE602005026595D1 (de) 2004-12-01 2011-04-07 Novo Nordisk As Injektionsvorrichtung
CN101107032B (zh) 2005-01-25 2010-09-29 诺和诺德公司 具有剂量反馈机构末端的注射装置
DE602006004452D1 (de) 2005-02-11 2009-02-05 Novo Nordisk As Injektionsvorrichtung
DE102005008280B3 (de) * 2005-02-23 2006-07-13 Tecpharma Licensing Ag Verabreichungsvorrichtung mit Anzeigetrommel
CN101217989B (zh) 2005-07-08 2010-10-20 诺沃-诺迪斯克有限公司 注射装置
EP1923084A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
CN101854968B (zh) * 2007-09-25 2013-07-24 伊莱利利公司 带有传动机构的剂量输送设备
US8647309B2 (en) 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
WO2010072229A1 (de) 2008-12-22 2010-07-01 Tecpharma Licensing Ag Dosiervorrichtung für eine injektionsvorrichtung

Also Published As

Publication number Publication date
MX2013003340A (es) 2013-12-02
EA201390247A1 (ru) 2013-09-30
BR112013006410B1 (pt) 2020-11-17
EP2618872B1 (en) 2020-04-15
BR112013006410A2 (pt) 2016-07-26
US8864721B2 (en) 2014-10-21
CA2813007C (en) 2016-05-17
UA109665C2 (xx) 2015-09-25
BR112013006410A8 (pt) 2020-11-03
KR101493626B1 (ko) 2015-02-13
EA024223B1 (ru) 2016-08-31
PL2618872T3 (pl) 2020-11-16
AU2011304788B2 (en) 2014-09-04
KR20130079510A (ko) 2013-07-10
CA2813007A1 (en) 2012-03-29
JP2013537819A (ja) 2013-10-07
US20130184653A1 (en) 2013-07-18
US20150038916A1 (en) 2015-02-05
CN103189084B (zh) 2015-03-25
EP2618872A1 (en) 2013-07-31
WO2012037938A1 (en) 2012-03-29
DK2618872T3 (da) 2020-06-02
CN103189084A (zh) 2013-07-03
AU2011304788A1 (en) 2013-03-14

Similar Documents

Publication Publication Date Title
JP5903102B2 (ja) 用量送達装置
JP2013537819A5 (enExample)
CN102740910B (zh) 没有传动装置的注射装置
JP5230722B2 (ja) ロックナットを備えた注射装置
CN101854968B (zh) 带有传动机构的剂量输送设备
US10188800B2 (en) Drive assembly for a drug delivery device and drug delivery device
EP3297707B1 (en) Injection device drive with two gear patterns
JP7174839B2 (ja) 注入装置

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20130513

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20130513

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140918

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20150717

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150721

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20151021

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160223

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160311

R150 Certificate of patent or registration of utility model

Ref document number: 5903102

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250