JP5886965B2 - 磁気共鳴撮像装置、診断支援システムおよびプログラム - Google Patents
磁気共鳴撮像装置、診断支援システムおよびプログラム Download PDFInfo
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Description
D(j,i)=|%SDj(Mi)−%SDs(Mi)|・・・(1)
そして、その結果を2乗し、差分和DF(j)の2乗に加算し、差分和DF(j)の2乗を更新する(ステップS1205)。具体的には、以下の式(2)に従って計算する。
DF(j)2=DF(j)2+D(j,i)2・・・(2)
以下、本発明の実施例を示す。
・疾患が膿瘍のレコードとの差分和(DF(膿瘍))
DF(膿瘍)=√((19-11)2+(19-10)2+(15-5)2+(15-20)2+(12-8)2)=16.9
・疾患が膠芽腫のレコードとの差分和(DF(膠芽腫))
DF(膠芽腫)=√((13-11)2+(12-10)2+(7-5)2+(18-20)2+(10-8)2)=4.5
・疾患が転移癌のレコードとの差分和(DF(転移癌))
DF(転移癌)=√((17-11)2+(19-10)2+(6-5)2+(16-20)2+(9-8)2)=11.6
・疾患が髄膜腫のレコードとの差分和(DF(髄膜腫))
DF(髄膜腫)=√((78-11)2+(92-10)2+(9-5)2+(356-20)2+(415-8)2)=538.3
1)膠芽腫(4.5)
2)転移癌(11.6)
3)膿瘍(16.9)
4)髄膜腫(538.3)
このとき、前記レコード510は、前記特徴項毎に登録値を備え、前記登録値は、前記採用データの前記信頼性指標の統計値としてもよい。
前記類似度は、前記特徴項毎の前記計測解析データの前記信頼性指標と前記レコード510の前記登録値との差分和が小さいものほど高いと判定されるよう構成してもよい。
Claims (9)
- 取得した核磁気共鳴信号に対し演算処理を行う計算部と、前記計算部における演算結果を表示する表示装置と、を備える磁気共鳴撮像装置であって、
前記計算部は、
前記核磁気共鳴信号から磁気共鳴スペクトルを生成するスペクトル生成部と、
前記磁気共鳴スペクトルを解析し、予め定めた特徴項毎の予め定めた信頼性指標を解析データとして算出するスペクトル解析部と、
所定の疾患であると確定診断された1以上の磁気共鳴スペクトルの前記解析データである確定解析データから作成されたレコードが疾患毎に登録される疾患毎スペクトルデータベースを用い、疾患が未知の磁気共鳴スペクトルから推定される疾患候補を抽出し、ユーザに提示する疾患候補抽出部と、を備え、
前記疾患候補抽出部は、前記疾患が未知の磁気共鳴スペクトルの解析データである計測解析データの中の、前記信頼性指標が示す信頼度が所定以上である計測解析データを用い、前記疾患毎スペクトルデータベースに登録されるレコードとの類似度を判定し、類似度が所定以上のレコードの疾患を、前記疾患候補とすること
を特徴とする磁気共鳴撮像装置。 - 請求項1記載の磁気共鳴撮像装置であって、
前記計算部は、さらに、前記疾患毎スペクトルデータベースの各レコードを生成するデータベース作成部を備え、
前記データベース作成部は、前記確定解析データの中の、前記信頼性指標が示す信頼度が所定以上である採用データを用いて前記レコードを作成すること
を特徴とする磁気共鳴撮像装置。 - 請求項2記載の磁気共鳴撮像装置であって、
前記レコードは、前記特徴項毎に登録値を備え、
前記登録値は、前記採用データの前記信頼性指標の統計値であること
を特徴とする磁気共鳴撮像装置。 - 請求項3記載の磁気共鳴撮像装置であって、
前記類似度は、前記特徴項毎に求める前記計測解析データの前記信頼性指標と前記レコードの前記登録値との差分の2乗の合計が小さいものほど高いと判定されること
を特徴とする磁気共鳴撮像装置。 - 請求項1記載の磁気共鳴撮像装置であって、
前記スペクトル解析部は、前記特徴項毎の濃度値および信号強度値の少なくとも一方を前記解析データとしてさらに算出し、
前記特徴項は、代謝物質および信号ピークのいずれか一方であり、
前記信頼性指標は、前記特徴項が代謝物質である場合、前記濃度値の標準偏差率であり、前記特徴項が信号ピークである場合、前記信号強度値から算出される信号雑音比であること
を特徴とする磁気共鳴撮像装置。 - 取得した核磁気共鳴信号から磁気共鳴スペクトルを生成する磁気共鳴撮像装置と、前記磁気共鳴撮像装置において得られた磁気共鳴スペクトルを解析するサーバと、を備える診断支援システムであって、
前記サーバは、
所定の疾患であると確定診断された1以上の磁気共鳴スペクトルから得た確定解析データを用いて作成されたレコードが疾患毎に登録される疾患毎スペクトルデータベースを用い、疾患が未知の磁気共鳴スペクトルから推定される疾患候補を抽出し、ユーザに提示する疾患候補抽出部、を備え、
前記確定解析データは、前記確定診断された1以上の磁気共鳴スペクトルを解析して得た、予め定めた特徴項毎の予め定めた信頼性指標を備え、
前記疾患候補抽出部は、前記疾患が未知の磁気共鳴スペクトルの解析データである計測解析データの中の、前記信頼性指標が示す信頼度が所定以上である計測解析データを用い、前記疾患毎スペクトルデータベースに登録されるレコードとの類似度を判定し、類似度が所定以上のレコードの疾患を、前記疾患候補とすること
を特徴とする診断支援システム。 - 請求項6記載の診断支援システムであって、
前記サーバは、さらに、前記疾患毎スペクトルデータベースの各レコードを生成するデータベース作成部を備え、
前記データベース作成部は、前記信頼性指標が示す信頼度が所定以上である前記確定解析データを用いて前記レコードを作成すること
を特徴とする診断支援システム。 - コンピュータを、
所定の疾患であると確定診断された1以上の磁気共鳴スペクトルから得た確定解析データを用いて作成されたレコードが疾患毎に登録される疾患毎スペクトルデータベースを用い、疾患が未知の磁気共鳴スペクトルから推定される疾患候補を抽出し、ユーザに提示する疾患候補抽出手段として機能させるためのプログラムであって、
前記確定解析データは、前記確定診断された1以上の磁気共鳴スペクトルをそれぞれ解析して得た予め定めた特徴項毎の予め定めた信頼性指標を備え、
前記疾患候補抽出手段は、さらに、前記疾患が未知の磁気共鳴スペクトルの解析結果である計測解析データの中の、前記信頼性指標が示す信頼度が所定以上である計測解析データを用い、前記疾患毎スペクトルデータベースに登録されるレコードとの類似度を判定し、類似度が所定以上のレコードの疾患を、前記疾患候補とすること
を特徴とするプログラム。 - 請求項8記載のプログラムであって、前記コンピュータを、さらに、
前記疾患毎スペクトルデータベースの各レコードを、前記信頼性指標が示す信頼度が所定以上である前記確定解析データを用いて生成するデータベース作成手段として機能させるためのプログラム。
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