JP5853632B2 - モデル動物、モデル動物の作製方法及び体内留置具の評価方法 - Google Patents
モデル動物、モデル動物の作製方法及び体内留置具の評価方法 Download PDFInfo
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- JP5853632B2 JP5853632B2 JP2011254814A JP2011254814A JP5853632B2 JP 5853632 B2 JP5853632 B2 JP 5853632B2 JP 2011254814 A JP2011254814 A JP 2011254814A JP 2011254814 A JP2011254814 A JP 2011254814A JP 5853632 B2 JP5853632 B2 JP 5853632B2
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- Surgical Instruments (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Description
2 バルーン部
3A 切片
3B 広いシート
3 シート
4 開口部
5 体内留置具(塞栓形成用コイル)
6 血管
7 糸
8 芯材
9 円柱体
10 球体
11 シリコンゴム膜
12 切り込み
20 シリコンチューブ
21 血管模擬ファントム装置
22 水槽
23 供給チューブ
24 回収チューブ
25 ホルダー
26 バッファ槽
27 ポンプ
Claims (12)
- 体内留置具の評価に用いるモデル動物であって、
金属製の前記体内留置具と、
前記体内留置具を充填した化成物製の中空体と、
を含み、
前記中空体が非ヒト動物の切開されていない血管の周囲に配置されるモデル動物。 - 前記中空体は、切開されていない前記血管に縫いつけられる若しくは手術用の接着剤で接着される又は血管を強く拘束しない止着具で機械的に血管の外周面に保持される請求項1に記載のモデル動物。
- 前記中空体の厚みは、200μm以上700μm以下である請求項1又は2記載のモデル動物。
- 前記中空体は、生体適合性を有する材料であるとともに、磁気共鳴を用いた撮影画像にて映らない材料で形成される請求項1〜3の何れか1項に記載のモデル動物。
- 前記中空体は、シリコンゴムで形成される請求項4に記載のモデル動物。
- 前記中空体の内部には、水の磁化率と等価なゲル状物も充填される請求項1〜5の何れか1項に記載のモデル動物。
- 前記ゲル状物は、寒天である請求項6に記載のモデル動物。
- 前記体内留置具は、塞栓治療に用いられるコイルである請求項1〜7の何れか1項に記載のモデル動物。
- 体内留置具の評価に用いるモデル動物の作製方法であって、
金属製の前記体内留置具を用意する工程と、
前記体内留置具を充填した化成物製の中空体を用意する工程と、
前記中空体を非ヒト動物の切開されていない血管の周囲に配置させる工程と、
を含むモデル動物の作製方法。 - 体内留置具の評価方法であって、
請求項1〜8の何れか1項に記載のモデル動物に対して、磁気共鳴を用いた撮影を行うことで、前記体内留置具を充填する前記中空体及びその中空体周辺の画像を取得する工程、
を含む体内留置具の評価方法。 - 前記磁気共鳴を用いた撮影は、MRI又はMRAである請求項10に記載の体内留置具の評価方法。
- 前記画像を、少なくとも1枚以上取得し、取得画像におけるアーチファクト画像の発生の有無で、前記体内留置具を評価する工程、
を含む請求項10又は11に記載の体内留置具の評価方法。
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JP2011254814A JP5853632B2 (ja) | 2011-11-22 | 2011-11-22 | モデル動物、モデル動物の作製方法及び体内留置具の評価方法 |
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JP2011254814A JP5853632B2 (ja) | 2011-11-22 | 2011-11-22 | モデル動物、モデル動物の作製方法及び体内留置具の評価方法 |
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JP2013106830A JP2013106830A (ja) | 2013-06-06 |
JP5853632B2 true JP5853632B2 (ja) | 2016-02-09 |
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Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2345376B1 (en) * | 2005-09-30 | 2012-07-04 | Cook Medical Technologies LLC | Coated vaso-occlusion device |
US20090326640A1 (en) * | 2007-02-01 | 2009-12-31 | Shinichi Yoshimura | Medical device for body cavity and method of producing the same |
JP5899864B2 (ja) * | 2011-11-22 | 2016-04-06 | 国立大学法人京都大学 | 塞栓形成用コイル |
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