JP5756409B2 - 呼気分析 - Google Patents
呼気分析 Download PDFInfo
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- JP5756409B2 JP5756409B2 JP2011549124A JP2011549124A JP5756409B2 JP 5756409 B2 JP5756409 B2 JP 5756409B2 JP 2011549124 A JP2011549124 A JP 2011549124A JP 2011549124 A JP2011549124 A JP 2011549124A JP 5756409 B2 JP5756409 B2 JP 5756409B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
- A61B5/4818—Sleep apnoea
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
- G01N33/4972—Determining alcohol content
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- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
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- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
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- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
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- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
Description
Claims (8)
- 呼気分析のための方法であって、
吐き出された空気の流れを受けるために被験者の口および鼻の開口に隣接して位置する、濃度保存効果を有する受け口(2;41)の入口開口(24)を通した測定セル(4)への空気取入れによるサンプリングを行なうステップを含み、
これにより前記流れは、前記受け口の形状により、前記測定セルに繋がる1つの分岐と前記入口に流れて戻る別の分岐とに分散され、これにより入射する流れが周囲空気と混ざることから保護され、これにより前記濃度保存効果が得られ、さらに
前記測定セルによる、たとえばエチルアルコールなどの揮発性有機物質、およびたとえば二酸化炭素などの生理基準物質の濃度の判定のステップを含む、方法。 - 周囲空気が測定セル(4)を通り、周囲空気に含まれる物質の分析がなされるゼロ化のステップと、
ゼロ化の後に、測定セル(4)からのセンサ信号によって準備ができていることが示されるステップと、
準備ができていることが示されたのちに、オペレータからの開始コマンドによって被験者の呼気の測定セル(4)への前記サンプリングが開始され、CO2濃度があるしきい値に達したときに測定セル(4)からのセンサ信号によって前記サンプリングが停止されるステップと、
前記サンプリングされた呼気に含まれる物質の分析がなされるステップと、を含み、ゼロ化および前記サンプリングのステップ以外においては、測定セル(4)中への空気の流入が停止される、請求項1に記載の方法。 - 前記サンプリング時の呼気のサンプル容量は50ml未満であり、
前記サンプリング時の前記測定セルへの呼気の流量は1秒当たり10ml以下であり、 前記サンプリングは本質的に非接触式であり、
前記サンプリング時の呼気の取入れはポンピング要素(16)によって制御されることを特徴とする、請求項1に記載の方法。 - 前記判定はIR分光分析によって行なわれ、前記呼気のサンプル内のエチルアルコール以外の揮発性有機物質の存在を含むことを特徴とする、請求項1に記載の方法。
- 測定セル(4)と、サンプリングの間に吐き出された空気を受けるために被験者の口および鼻に向けられる入口開口(24)を含む、前記測定セルに接続される受け口(2,41)と、前記受け口から前記測定セルへ呼気を送るコネクタ(45)とを備える呼気分析器であって、
受け口(2,41)は、吐き出された空気の流れの一部が、前記コネクタ(45)を介して前記測定セル(4)に送られ、吐き出された空気の流れの一部が、外壁に沿って前記入口開口(24)に還流して戻るような外形を有するカップ、漏斗、または柄杓の形状を有し、また吐き出された空気の流れの一部が、外壁に沿って前記入口開口(24)に還流して戻るように空気の流れを制御する内壁(43)が設けられていることを特徴とする、呼気分析器。 - 前記受け口(2;41)は交換可能であり、前記呼気のサンプル内から液体の滴または粒子を分離するための要素と、たとえば鼻および顎先などの身体の部分への固定のための機械的支持要素とを含むことを特徴とする、請求項5に記載の呼気分析器。
- 前記測定セル(4)は、多変量IR分光分析のための光源、反射器、分散要素、および検出器を含むことを特徴とする、請求項5に記載の呼気分析器。
- 片手で操作されるハンドユニット(1)と、受け口(2;41)と、非作動時に前記ハンドユニット(1)を置くためのドッキングステーション(3)とを含み、
前記測定セル(4)は、前記ハンドユニット(1)に収容されていることを特徴とする、請求項5に記載の呼気分析器。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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SE0900162-9 | 2009-02-10 | ||
SE0900162 | 2009-02-10 | ||
PCT/SE2010/050146 WO2010093317A1 (en) | 2009-02-10 | 2010-02-08 | Breath analysis |
Publications (2)
Publication Number | Publication Date |
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JP2012517276A JP2012517276A (ja) | 2012-08-02 |
JP5756409B2 true JP5756409B2 (ja) | 2015-07-29 |
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Application Number | Title | Priority Date | Filing Date |
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JP2011549124A Active JP5756409B2 (ja) | 2009-02-10 | 2010-02-08 | 呼気分析 |
Country Status (6)
Country | Link |
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US (1) | US20110283770A1 (ja) |
EP (1) | EP2395915B1 (ja) |
JP (1) | JP5756409B2 (ja) |
KR (1) | KR101699000B1 (ja) |
CN (1) | CN102316801B (ja) |
WO (1) | WO2010093317A1 (ja) |
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-
2010
- 2010-02-08 KR KR1020117021324A patent/KR101699000B1/ko active IP Right Grant
- 2010-02-08 US US13/147,496 patent/US20110283770A1/en not_active Abandoned
- 2010-02-08 CN CN2010800071505A patent/CN102316801B/zh active Active
- 2010-02-08 WO PCT/SE2010/050146 patent/WO2010093317A1/en active Application Filing
- 2010-02-08 JP JP2011549124A patent/JP5756409B2/ja active Active
- 2010-02-08 EP EP10741480.7A patent/EP2395915B1/en active Active
Also Published As
Publication number | Publication date |
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EP2395915A1 (en) | 2011-12-21 |
CN102316801A (zh) | 2012-01-11 |
WO2010093317A1 (en) | 2010-08-19 |
EP2395915B1 (en) | 2019-01-16 |
EP2395915A4 (en) | 2013-01-23 |
CN102316801B (zh) | 2013-12-04 |
US20110283770A1 (en) | 2011-11-24 |
JP2012517276A (ja) | 2012-08-02 |
KR101699000B1 (ko) | 2017-01-23 |
KR20110118816A (ko) | 2011-11-01 |
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