JP5722632B2 - エネルギー利用疾病の治療 - Google Patents

エネルギー利用疾病の治療 Download PDF

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Publication number
JP5722632B2
JP5722632B2 JP2010546398A JP2010546398A JP5722632B2 JP 5722632 B2 JP5722632 B2 JP 5722632B2 JP 2010546398 A JP2010546398 A JP 2010546398A JP 2010546398 A JP2010546398 A JP 2010546398A JP 5722632 B2 JP5722632 B2 JP 5722632B2
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Prior art keywords
acid
iminosugar
acids
diabetes
insulin
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JP2010546398A
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Japanese (ja)
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JP2011512347A5 (https=
JP2011512347A (ja
Inventor
ナッシュ，ロバート，ジェームズ
ウィルソン，フランシス，ザビエル
ホーン，グレイム
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Summit Therapeutics Ltd
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Summit Corp PLC
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Priority claimed from GB0802907A external-priority patent/GB0802907D0/en
Priority claimed from GB0802903A external-priority patent/GB0802903D0/en
Priority claimed from GB0802904A external-priority patent/GB0802904D0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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    • A—HUMAN NECESSITIES
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    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
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    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Child & Adolescent Psychology (AREA)
JP2010546398A 2008-02-18 2009-02-17 エネルギー利用疾病の治療 Active JP5722632B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0802907.6 2008-02-18
GB0802904.3 2008-02-18
GB0802903.5 2008-02-18
GB0802907A GB0802907D0 (en) 2008-02-18 2008-02-18 Method for monitoring the quality of a herbal food additive
GB0802903A GB0802903D0 (en) 2008-02-18 2008-02-18 Treatment of diabetes
GB0802904A GB0802904D0 (en) 2008-02-18 2008-02-18 Treatment of metabolic syndrome
PCT/GB2009/000417 WO2009103953A1 (en) 2008-02-18 2009-02-17 Treatment of energy utilization disease

Publications (3)

Publication Number Publication Date
JP2011512347A JP2011512347A (ja) 2011-04-21
JP2011512347A5 JP2011512347A5 (https=) 2013-04-11
JP5722632B2 true JP5722632B2 (ja) 2015-05-27

Family

ID=40589554

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010546398A Active JP5722632B2 (ja) 2008-02-18 2009-02-17 エネルギー利用疾病の治療

Country Status (7)

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US (3) US20110015226A1 (https=)
EP (1) EP2257286B1 (https=)
JP (1) JP5722632B2 (https=)
CN (1) CN102006869B (https=)
CA (1) CA2752868C (https=)
ES (1) ES2620743T3 (https=)
WO (1) WO2009103953A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10273598B2 (en) 2009-12-22 2019-04-30 Element Six Technologies Limited Synthetic CVD diamond
KR101598935B1 (ko) * 2010-04-16 2016-03-03 씨제이제일제당(주) 레바우디오사이드 ａ의 생산 공정에서 발생하는 부산물을 재활용하여 고수득율의 레바우디오사이드 ａ를 제조하는 방법
GB201117490D0 (en) 2011-10-11 2011-11-23 Phytoquest Ltd Anti-inflammatory compounds
GB2496388B (en) * 2011-11-08 2014-10-08 Phynova Ltd Morus extracts rich in n-acids of imino sugars and or pipecolic acids
GB201313440D0 (en) 2013-07-29 2013-09-11 Phytoquest Ltd Characterization of rice
JP6283569B2 (ja) * 2014-05-26 2018-02-21 株式会社シャローム 脂肪蓄積抑制物質の製造方法
CN105624181B (zh) * 2014-11-03 2019-06-11 中国科学院微生物研究所 一种高通量鉴定产生1-脱氧野尻霉素菌株的方法
KR102408480B1 (ko) * 2018-05-30 2022-06-10 이삼구 당뇨질환의 치료용 조성물
WO2021019194A1 (en) * 2019-07-26 2021-02-04 Phytoquest Limited Bioactive phytochemicals

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154918C (no) 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
WO1992021657A1 (en) 1991-05-30 1992-12-10 The Scripps Research Institute Omega-deoxy-azasugars
US5863903A (en) 1994-03-09 1999-01-26 Novo Nordisk A/S Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes
WO2000056334A1 (en) * 1999-03-19 2000-09-28 The Trustees Of Boston College Use of imino sugars for anti-tumor therapy
WO2000066105A2 (en) * 1999-04-30 2000-11-09 The Trustees Of Boston College Treatment of epilepsy with imino sugars
DE60308378T2 (de) * 2002-03-13 2007-09-20 Unither Pharmaceuticals, Inc. Nicht-Hormonal Verfahren zur männlichen Verhütung
US20060025449A1 (en) 2004-03-25 2006-02-02 United Therapeutics Use of N-substituted imino sugars for appetite suppression
JP2007262017A (ja) 2006-03-29 2007-10-11 Ajinomoto Co Inc ピペコリン酸含有抗糖尿病組成物

Also Published As

Publication number Publication date
CN102006869A (zh) 2011-04-06
US20160151341A1 (en) 2016-06-02
EP2257286B1 (en) 2016-12-28
WO2009103953A1 (en) 2009-08-27
US20110015226A1 (en) 2011-01-20
EP2257286A1 (en) 2010-12-08
JP2011512347A (ja) 2011-04-21
ES2620743T3 (es) 2017-06-29
US20140011841A1 (en) 2014-01-09
CA2752868A1 (en) 2009-08-27
CA2752868C (en) 2018-11-27
US10842784B2 (en) 2020-11-24
CN102006869B (zh) 2013-11-06

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