JP5666343B2 - Biological healing power improvement device and operation method of biological healing power improvement device - Google Patents

Description

  The present invention relates to a living body healing power improvement device using increase / decrease in oxygen concentration under a reduced pressure environment, and further to an operating method of the living body healing power improvement device.

  The present inventor has proposed an optimum pressure regulating device and pressure regulating method for performing an air bath using stimulation due to a temperature difference (see Patent Document 1). Furthermore, abnormal body tissue, body by a stimulus that continuously repeats between a reduced pressure state above the threshold pressure generated by the pressure regulator and a normal pressure or a broad normal pressure state higher than the reduced pressure and lower than the normal pressure. A human healing ability improvement device was proposed after confirming the action of human healing power effect to return organs and the like to healthy body tissues and body organs.

Japanese Patent No. 4477690

  The inventor of the present invention continuously repeats the natural healing power effect between a reduced pressure state that is higher than or equal to a threshold pressure generated in the pressure regulator and a normal pressure or a broad normal pressure state that is higher than the reduced pressure state and lower than the normal pressure. I was convinced that by stimulating abnormal body tissues, body organs, etc., a greater natural ability to improve healing power to return to healthy body tissues, body organs.

  Furthermore, when verifying the action effect of this ability to improve the body healing power, it was confirmed that there is another approach to the ability to improve the body healing ability, and thus the present invention has been made.

  That is, an object of the present invention is to obtain a living body healing power improvement device that can give a stimulus that improves the natural healing power of a living body. It is another object of the present invention to obtain a method for operating the device for applying the stimulus well.

The living body healing power improvement device according to the invention described in claim 1 includes a decompression chamber that holds the subject in a decompressed environment below normal pressure,
Oxygen supply means for supplying the subject in the decompression chamber with an oxygen concentration higher than the oxygen concentration in the atmosphere;
Oxygen supply control means for controlling the supply of oxygen to be supplied to the subject by the oxygen supply means so that the oxygen concentration is equal to or higher than the oxygen partial pressure at normal pressure ,
The oxygen supply control means repeatedly controls the supply of oxygen supplied to the subject by the oxygen supply means to a normal pressure oxygen concentration at normal pressure and a high oxygen concentration not more than twice the oxygen partial pressure at normal pressure. It is characterized by.

  According to a second aspect of the present invention, there is provided a living body healing power improving device, wherein the decompression environment of the decompression chamber according to the first aspect corresponds to a decompression state at an altitude of 1000 to 3000 m.

The operation method of the biohealing power improvement device according to the invention described in claim 3 includes a decompression chamber that holds the subject in a decompressed environment lower than normal pressure, and an oxygen concentration in the subject in the decompression chamber is determined from the oxygen concentration in the atmosphere. An oxygen supply means for supplying the increased amount of oxygen, and an oxygen supply control means for controlling the supply of oxygen supplied to the subject by the oxygen supply means so that the oxygen concentration is equal to or higher than the partial pressure of oxygen at normal pressure. A method of operating the force-enhancing device,
After holding the subject in a reduced pressure environment below normal pressure, the subject repeatedly changed the normal pressure oxygen concentration at the normal pressure and the high oxygen concentration less than twice the oxygen partial pressure at the normal pressure. The air to be supplied is supplied.

  INDUSTRIAL APPLICABILITY The present invention has an effect that it is possible to obtain a living body healing power improvement device that can satisfactorily give a stimulus for improving the natural healing power of a living body and an operation method of the living body healing power improvement device.

It is a diagram which shows the change of the oxygen utilization rate in the expiration | expired_air at the time of controlling a pressure reduction process and a pressurization process repeatedly continuously. It is a front view which shows the structure of one Example of the biohealing power improvement apparatus of this invention. FIG. 3 is a plan view of FIG. 2. FIG. 3 is a side view of FIG. 2. FIG. 3 is a flowchart showing driving of the control device of FIG. 2, FIG. A is a flowchart showing a decompression step, and FIG. B is a flowchart showing an oxygen supply step. It is a diagram which shows the verification result of a living body healing power improvement effect. It is a diagram which shows another verification result of a biological healing power improvement effect.

  In the living body healing power improvement device of the present invention, a decompression chamber that holds a subject in a decompressed environment below normal pressure (that is, standard atmospheric pressure (1 atm (1013 hPa))), and an oxygen concentration to the subject in the decompression chamber Oxygen supply means for supplying the oxygen by increasing the oxygen concentration therein, and the oxygen supplied to the subject by the oxygen supply means has an oxygen concentration equal to or higher than the partial pressure of oxygen at normal pressure (ie, 0.21 atm, 213 hPa). And oxygen supply control means for controlling the supply. Thereby, the stimulus which improves the natural healing power of a living body can be given satisfactorily. The room temperature in the hermetic chamber is set to a comfortable temperature for the subject, and specifically, it should not be out of the range of 20 ° C to 25 ° C.

  The term “biological healing power” added in the present invention refers to the power to restore an abnormal state to a healthy state by the recovery function inherent to the living body, including body fluid components such as blood, blood pressure, It refers to the restoration and healing of abnormal environments such as repair of tissue damage and the elimination of foreign substances (non-self) such as pathogenic microorganisms and viruses. More specifically, it refers to a function of trying to cure a disease such as a disorder of various functions of the body or an abnormal state that is not healthy to a normal state. Therefore, “improving the healing power of the living body” means improving the natural healing power itself, the speed of the reaction to quickly recognize that it is in an abnormal state, and the response to return to the normal state It also includes further improving the speed and the like.

  Examples include reduction and disappearance of tumor cells that are not healthy cells, improvement of immune system hypersensitivity such as rheumatism, improvement of osteoporosis that is not healthy bone tissue, improvement of abnormal glucose metabolism, etc. It is thought to include improvement of thrombosis, prevention of angina pectoris, cerebral thrombosis, intracerebral hemorrhage by dissolution of thrombus, improvement of dementia by improvement of cerebral blood flow, and the like.

  In the present invention, it seems that the detailed action mechanism (action mechanism) of the biohealing power improvement effect by increasing the oxygen concentration under reduced pressure environment will be elucidated by future verification and accumulation of data, etc. The hypothesis of mechanism of action was considered.

hypothesis. The defense mechanism of low oxygen When the biological “defense mechanism” goes from the lowland to the highland (that is, toward the lower oxygen concentration), the theoretical value (oxygen in the flatland) is constantly calculated during the movement from the lowland to the highland. It is considered that the amount of oxygen is greater than the amount of oxygen used). This is judged to be an increase in the production of “ATP” because an increase in body temperature is observed even when the moving speed from the normal pressure state to the reduced pressure state is changed.

  Conversely, when going from high altitude to low altitude (that is, when going from low oxygen concentration to normal), the “defense mechanism” is slow because the oxygen concentration is high, that is, the cell tends to make ATP. Acts. Therefore, there is a condition that the theoretical value and the moving speed almost coincide. In order to increase the production of ATP, it is necessary to make the moving speed faster than this. In other words, the faster the speed, the easier it is to produce ATP.

  FIG. 1 is a diagram showing a change in oxygen utilization rate during expiration when the decompression step and the pressurization step are continuously and repeatedly controlled. In this hypothesis, we focused on the oxygen utilization rate in exhaled breath due to pulmonary breathing at rest. In view of energy metabolism, a constant amount of oxygen carried by hemoglobin must always be supplied in order to produce “ATP”.

  That is, assuming that oxygen equivalent to 25.0% of exhaled air is used on a flat ground, for example, the oxygen concentration decreases by 10% at an altitude of 1000 m, so that 27.8% oxygen in the exhaled air is supplemented by this. Is considered to be used. Similarly, at an altitude of 2000 m, it is considered that 31.3% is used compared to 25.0% on flat ground. This is all determined by the subject's “defense mechanism”.

  In this case, there is a margin in the amount of oxygen in exhaled air up to an altitude of about 3000 m, but conversion is possible. However, if oxygen becomes thinner than that, there may be individual differences in the amount of oxygen adsorbed to hemoglobin, which may cause hypoxia injury. Here, it seems that the activation of the “defense mechanism” of the living body is caused by pressure.

  In other words, it was thought that the oxygen partial pressure in the air itself was reduced by the reduction of the air pressure, and the “defense mechanism” due to low oxygen in the living body was activated. Therefore, when a living body is exposed to such a low-pressure state and a high-concentration oxygen atmosphere is formed, high-concentration oxygen is sent to mitochondria, and as a result, increased production of ATP can be expected. Increased body temperature will cause an increase in body temperature. It is considered that the natural healing power improving effect was obtained by the increased production of ATP.

  The decompression environment of the decompression chamber in the present invention may be any pressure that is lower than the decompression state in which the “defense mechanism” is activated and higher than the decompression state in which the health of the subject in the decompression chamber is not threatened. Strictly speaking, the depressurized state in which the “defense mechanism” occurs is subject to individual differences depending on the subject, and it seems that accurate pressure cannot be measured. It seems to be activated.

  Further, there is an individual difference in the threshold value of the reduced pressure state in which the health of the subject is not threatened, and the threshold value of the atmospheric pressure changes depending on a healthy person or a person suffering from a disease. Furthermore, the threshold can be lowered by experience, and conversely, the threshold may be increased by physical condition. In general, a pressurized cabin in an aircraft is set to an atmospheric pressure state (about 780 hPa) at an altitude of 2000 m at an altitude of 12000 m and can be used even by a person suffering from a disease. Therefore, the threshold value of a general healthy subject is at least 700 mPa with an altitude of about 3000 m or less, preferably at an altitude of 2000 m (about 795 hPa).

  As the oxygen supply means in the present invention, any oxygen supply means may be used as long as the oxygen concentration is supplied to the subject in the decompression chamber by increasing the oxygen concentration in the atmosphere. Specifically, when oxygen is introduced into the decompression chamber, oxygen is supplied. When adding oxygen from a cylinder or taking outside air into the decompression chamber, the oxygen separation membrane separates oxygen and other substances in the air and adds it to the outside air taken in from another inlet. To improve the oxygen concentration. Oxygen may be uniformly added to the air in the entire decompression chamber, or the oxygen partial pressure in the mask that supplies air to each subject in the decompression chamber may be raised. The latter has the advantage of requiring a small amount of oxygen to be supplied.

  As the oxygen supply control means, specifically, the supply of oxygen supplied to the subject by the oxygen supply means is controlled so as to have an oxygen concentration equal to or higher than the oxygen partial pressure at normal pressure. In any case, the air pressure in the decompression chamber where the subject stays is maintained in a decompressed environment lower than the normal pressure, and oxygen is supplied to the subject in the decompression chamber at a concentration equal to or higher than the partial pressure of oxygen at normal pressure. What is necessary is just to be comprised.

  As the air in which oxygen has a concentration equal to or higher than the oxygen partial pressure at normal pressure, the highest concentration is a concentration not exceeding twice the oxygen partial pressure at normal pressure. This is because an excessively high concentration of oxygen may cause damage to the subject's lungs. Conversely, the lowest concentration of oxygen partial pressure in the air supplied to the subject is a concentration that does not fall below the oxygen partial pressure at normal pressure. Although the oxygen partial pressure at normal pressure corresponds to 0.21 atm, the present invention keeps the subject in a reduced pressure environment below 1 atm, so when this oxygen concentration is below, various oxygen deficiencies such as nausea and dizziness This is because the symptoms may occur.

  In the living body healing power improvement apparatus of the present invention, one or more other various means for improving the natural healing power of the living body that has entered the hermetic portion may be provided. For example, it is further provided with a humidifying means for imparting humidity in the hermetic part that decreases in a reduced pressure state, further provided with a heating means for imparting a temperature in the hermetic part that is reduced in a reduced pressure state, or negative ions in the hermetic part An anion imparting means for increasing the number of ions may be further provided.

  In the present invention according to the method, after the subject is held in a reduced pressure environment below normal pressure, the biological healing power improvement device is provided by supplying the subject with air having a concentration equal to or higher than the oxygen partial pressure at normal pressure. Can be operated.

  As the biohealing power improvement device in the present invention, an airtight part that can be airtight, a decompression pump that communicates with an exhaust port of the airtight part and reduces the pressure in the airtight part, and a threshold pressure at which the air pressure of the airtight part is predetermined What is necessary is just to be provided with the excessive pressure reduction prevention apparatus which prevents that it becomes the excessive pressure reduction below. In addition, although the airtight part in this invention is not assumed when it pressurizes positively more than a normal pressure (standard atmospheric pressure), the pressurization of a little over normal pressure may naturally be an error range.

  The airtight part of the present invention includes an airtight part that can withstand pressure change between a reduced pressure state equal to or higher than a threshold pressure and a normal pressure or a broad normal pressure state that is higher than the reduced pressure state and lower than the normal pressure. If it is. The material constituting the hermetic portion may be any material that maintains airtightness and can withstand the pressure change between the reduced pressure state and the wide range normal pressure state, and is made of metal, resin, wood or the like alone or in combination. The

Example 1 Configuration of Biohealing Power Improvement Device FIG. 2 is a front view showing the configuration of an embodiment of the biohealing power improvement device of the present invention. FIG. 3 is a plan view of FIG. FIG. 4 is a side view of FIG. As shown in the figure, the living body healing power improvement device 10 of the present embodiment includes an airtight part 11 composed of a plurality of panel plates 30 and a decompression pump 13 communicating with an exhaust pipe 12 having one end opened inside the airtight part 11. A filter 15 is attached to the outside of the airtight part 11 at the other end of the air supply pipe 14 whose one end is opened at a position facing the exhaust pipe 12 in the airtight part 11.

  The external appearance of the airtight part 11 is a housing composed of a plurality of panel plates 30 having substantially the same size. In this embodiment, it is composed of 14 panel plates. On the front and back (not shown), an entrance / exit panel 31 having an airtight door 32 provided with two windows 33 at the center is used. Three side panels 34 each having two windows 33 are connected and used on both side surfaces. Three ceiling panels 35 are connected to the ceiling surface. In the same manner as the ceiling surface, three floor panels 36 are connected to the floor surface.

  Although not shown, each panel plate 30 has a rim portion standing so as to surround four sides of the rectangle, and the panel plates adjacent to each other through the panel plates 30 or a joining member by the rim portion. 30 is connected. By connecting an elastic rubber plate between the rim portions of the panel plates 30 to be joined or between the rim portion of the panel plates and the joining member, airtightness between the connecting portions is maintained.

  An air supply pipe 14 is arranged on one side of the front entrance panel 31, and a pressure control valve 16 is attached in the middle of the air supply pipe 14 to adjust the pressure loss caused by the opening degree of the pressure control valve 16. As a result, the outside air that has passed through the filter 15 is naturally sucked continuously in accordance with the atmospheric pressure in the airtight portion 11. The opening degree of the pressure control valve 16 is performed by a decompression control device 22 described later. Note that the pressure control valve 16 has a structure that cannot be completely closed, thereby functioning as an oxygen deficiency prevention means.

  In the middle of the air supply pipe 14, an oxygen supply pipe 25 communicating with an oxygen cylinder 23 as oxygen supply means is joined via an oxygen supply control device 24. The air supply pipe 14 always supplies outside air into the airtight portion 11, and the control device 24 controls oxygen in the oxygen cylinder 23 that is further supplied to the outside air.

  An exhaust pipe 12 is arranged on the other side of the front entrance panel 31. An exhaust solenoid valve 17 is attached in the middle of the exhaust pipe 12, and a branch pipe 18 and an outside air are provided on the decompression pump 13 side. An over-decompression prevention pipe 20 that communicates with the outside air via the electromagnetic valve 19 is arranged. Further, the airtight portion 11 is provided with a number of pressure sensors 21 for measuring the internal air pressure. When the air pressure in the airtight portion 11 falls below a preset threshold value due to some abnormality, the decompression pump 13 is stopped. Then, when the outside air solenoid valve 19 is opened and outside air is sucked in, excessive decompression can be prevented.

  A decompression control device 22 as a decompression control means for controlling the drive of the decompression pump 13 is arranged on the top of the decompression pump 13, and the numerical value of the pressure sensor 21 of the airtight portion 11 is also input to the decompression control device 22. The drive of the electromagnetic valves 17 and 19 and the opening degree of the pressure control valve 16 are also controlled.

  FIG. 5 is a flowchart showing the driving of the control device of FIG. 2, FIG. 5 a is a flowchart showing a pressure reduction process, and FIG. 5 b is a flowchart showing an oxygen supply process. As shown in FIG. a, in the decompression step, the decompression control device 22 drives the decompression pump 13. In this case, it goes without saying that the external electromagnetic valve 19 is closed and the exhaust electromagnetic valve 17 is opened.

  When the decompression pump 13 is driven, the opening of the pressure control valve 16 is set to the minimum opening so that rapid decompression is performed. The atmospheric pressure is periodically checked to determine whether the target pressure reduction value is set in advance. When the target pressure reduction value is reached, the pressure reduction pump 13 is stopped. When the decompression pump 13 is stopped, the exhaust solenoid valve 17 is closed to maintain the pressure inside the hermetic portion 11.

  Moreover, since the pressure control valve 16 has a structure that is not blocked, the pressure gradually increases when the drive of the decompression pump 13 is stopped. Therefore, when the target decompression state is maintained for a long time, when a certain pressure rises with reference to the target pressure, the exhaust electromagnetic valve 17 is opened and the decompression pump 13 is driven again.

  After the atmospheric pressure in the airtight portion 11 becomes a reduced pressure body, oxygen supplied to the subject in the airtight portion 11 is supplied so as to have an oxygen concentration equal to or higher than the oxygen partial pressure at normal pressure. As shown in FIG. b, in the oxygen supply step, an air supply pipe 14 for supplying outside air into the airtight part 11 while opening an oxygen supply valve for supplying oxygen in the oxygen cylinder 23 to the oxygen supply pipe 25 in the oxygen control device 24. The oxygen partial pressure is measured by the oxygen concentration meter 26 and the pressure sensor 21. It is determined whether the target oxygen partial pressure value set in advance is reached, and when the target partial pressure value is reached, the target is obtained by squeezing the opening of the oxygen supply valve in the oxygen control device 24 to the minimum. The oxygen partial pressure can be supplied to the subject in the airtight part 11.

  In addition, in the room of the airtight part 11 of a present Example, you may provide the apparatus which makes test subject's room comfortable, such as illumination, an air-conditioner, floor heating, a CD player, and a television, as needed. In addition, about an air conditioner, it is necessary to ensure airtightness so that the drain in the room | chamber interior of an airtight part may be discharged | emitted indoors.

Example 2: Verification of the effect of improving the healing power of living bodies As shown in the defense mechanism by low oxygen, in a living body exposed to a low-pressure state, the oxygen partial pressure in the air itself is reduced due to a decrease in the air pressure. It is thought that a “defense mechanism” due to hypoxia is activated in the body. When a living body is exposed to a low pressure state and a high concentration oxygen atmosphere is formed, high concentration oxygen is sent to the mitochondria, and as a result, ATP Increased production can be expected. For this reason, I think that the natural healing power improvement effect is acquired by ATP whose production increased.

  The body temperature of the palm (palm) was measured as verification of the effect of the biological healing power improvement apparatus of this invention by seeing a rise in body temperature due to an increase in ATP production. The following verification data is obtained by measuring the temperature of the palm over time when the subject is exposed to a low pressure state at an altitude of about 2000 m and then the oxygen partial pressure in the low pressure state is increased.

  Specifically, as shown in Table 1 and FIG. 6, as a verification result of the biohealing power improvement effect, after the subject enters the airtight part of the biohealing power improvement apparatus shown in FIGS. 2 to 4, Air was depressurized. After 9 minutes, it was confirmed that a low pressure state (795 hPa, oxygen partial pressure 167 hPa) was reached at an altitude of about 2000 m, and this was maintained. Moreover, the air which added oxygen to external air was supplied to the test subject with the mask. In addition, the air temperature in an airtight part was 20 to 25 degreeC.

  It was confirmed that a substantially constant oxygen partial pressure was given to the subject after 20 minutes, and this was maintained for 45 minutes in this state. Thereafter, the mask was removed in 5 minutes, and simultaneously the reduced pressure state was changed to the normal pressure state. During the above process, the palm temperature was measured over time. The palm temperature was measured with a skin infrared thermometer (trade name: Thermo Focus Pro).

  As another verification result of the biohealing power improvement effect, as shown in Table 2 and FIG. 7, the subject enters the airtight part of the biohealing power improvement apparatus shown in FIGS. did. After 9 minutes, it was confirmed that a low pressure state (795 hPa, oxygen partial pressure 167 hPa) was reached at an altitude of about 2000 m, and this was maintained. Moreover, the air which added oxygen to external air was supplied to the test subject with the mask.

  When the oxygen partial pressure becomes 395 hPa after 20 minutes, the additional oxygen is decreased. After 30 minutes, the oxygen partial pressure is confirmed to be the same as the normal pressure state (213 hPa), and the additional oxygen is increased again. 40 minutes later, when the oxygen partial pressure reached 395 hPa, the additional oxygen was reduced, and after 45 minutes, the reduced pressure state in the hermetic zone was changed to the normal pressure state. During the above process, the palm temperature was measured over time. The palm temperature was measured with a skin infrared thermometer (trade name: Thermo Focus Pro).

  As shown in Tables 1 and 2 and FIGS. 6 and 7, it was confirmed that palm temperature was increased by adding oxygen to a living body exposed to a low pressure state. Furthermore, it was confirmed that the increase in palm temperature was further improved by increasing and decreasing the amount of added oxygen within a certain time.

  ADVANTAGE OF THE INVENTION According to this invention, the living body healing power improvement apparatus which can give the stimulus which improves the natural healing power of a biological body better, and its operating method are obtained, an abnormal body tissue, a body organ, etc. are made into a healthy body. The effect of healing power to return to tissues and body organs becomes more effective.

10 ... living body healing power improvement device,
11 ... Airtight part,
12 ... exhaust pipe,
13 ... decompression pump,
14 ... Air supply pipe,
15 ... filter,
16 ... pressure regulating valve,
17 ... Solenoid valve for exhaust,
18 ... branch pipe,
19 ... Solenoid valve for outside air,
20 ... pipe for preventing excessive decompression,
21 ... Pressure sensor,
22 ... decompression control device,
23 ... oxygen cylinder,
24. Oxygen supply control device,
25. Oxygen supply pipe,
26 ... Oxygen concentration meter,
30 ... Panel board,
31 ... Entrance panel,
32 ... Airtight door,
33 ... window,
34 ... side panel,
35 ... ceiling panel,
36 ... floor panel,

Claims (3)

A decompression chamber for holding the subject in a decompressed environment below normal pressure;
Oxygen supply means for supplying the subject in the decompression chamber with an oxygen concentration higher than the oxygen concentration in the atmosphere;
Oxygen supply control means for controlling the supply of oxygen to be supplied to the subject by the oxygen supply means so that the oxygen concentration is equal to or higher than the oxygen partial pressure at normal pressure ,
The oxygen supply control means repeatedly controls the supply of oxygen supplied to the subject by the oxygen supply means to a normal pressure oxygen concentration at normal pressure and a high oxygen concentration not more than twice the oxygen partial pressure at normal pressure. A biological healing power improvement device characterized by the above.   The decompression environment of the decompression chamber corresponds to a decompression state at an altitude of 1000 to 3000 m. Supplied to the subject by a decompression chamber that holds the subject in a decompressed environment below normal pressure, an oxygen supply means that supplies the subject in the decompression chamber with an oxygen concentration higher than the oxygen concentration in the atmosphere, and an oxygen supply means An operation method of a living body healing power improvement device comprising oxygen supply control means for controlling supply of oxygen so as to have an oxygen concentration equal to or higher than an oxygen partial pressure at normal pressure,
After holding the subject in a reduced pressure environment below normal pressure, the subject repeatedly changed the normal pressure oxygen concentration at the normal pressure and the high oxygen concentration less than twice the oxygen partial pressure at the normal pressure. A method for operating a living body healing power improvement device, characterized by supplying air to be used.

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