JP5597019B2 - Biological light measurement device and biological light measurement method - Google Patents

Description

  The present invention relates to a living body measuring apparatus and an ecological measuring method for measuring information inside a living body using light, and more particularly to a communication technique between a living body and a measuring apparatus.

  The biological light measurement device irradiates the living body with light in the visible to infrared region, measures the light passing through the living body or reflected inside the living body, such as blood circulation, hemodynamics and hemoglobin amount change in the living body. It is a device that measures information. These can be easily measured without causing any harm to the subject with low restraint. In recent years, imaging of measurement data by a multi-channel device has been realized, and clinical application is expected.

  The biological light measurement apparatus includes a light irradiation unit that irradiates a subject with light, a light detection unit that measures light that has passed or reflected, and a control unit that controls the operation of each unit and processes the detected light. . The light irradiation unit and the light detection unit constitute a measuring instrument (probe) and are attached by the subject. Signal transmission between the probe and the control unit is performed by wired communication via a cable such as an optical fiber or an electric wire or wireless communication using radio waves (for example, see Patent Document 1 and Patent Document 2).

JP 2004-337625 A Japanese Patent No. 3593764

  Since the biological optical measurement device is simple and non-invasive, it is relatively easy to handle during measurement, and is used in various situations. For this reason, not only when the subject is stationary, but also the measurement requirements during exercise are increasing. For example, information such as the above-described changes in blood circulation, hemodynamics, and hemoglobin amount is obtained by activating the brain and measuring blood changes in the activated cerebral cortex. At this time, in order to activate the brain, measurement may be performed while applying a physiological stimulus to the subject or performing an active task on the subject.

  The cable communication method for transmitting and receiving signals between the probe and the control unit using a cable is relatively easy in principle and structure, but the use of the cable increases the weight and restricts the length. Further, the position of the probe attached to the subject may be displaced due to the weight of the cable during measurement, and measurement data may not be stable.

  On the other hand, since there is no cable in the wireless communication method in which signals are transmitted and received between the two, the subject's restraint is further reduced, and measurement can be performed in a more free state (exercise load or the like). However, use of radio waves restricts the use environment, and there are cases where use is restricted in, for example, hospitals and public places.

  The present invention has been made in view of the above circumstances, and provides a technique for improving the usability by increasing the measurement flexibility of the biological optical measurement device by reducing the restraint of the subject regardless of the usage environment. The purpose is to do.

  The present invention uses biological communication to transmit and receive signals between a probe arranged in the vicinity of a subject and a control unit that controls the entire apparatus and processes detected light. The probe includes a light irradiation unit that generates and emits light and a light detection unit that detects light, and a signal transmitted and received between the probe and the control unit is a control signal that controls light irradiation. The detected passing light is converted into an electric signal.

  Specifically, a probe that irradiates the subject with irradiation light, detects passing light from the subject, and outputs it as an electrical signal, and controls the irradiation of light at the probe and outputs the electric light output from the probe. A biological light measurement apparatus including a control unit configured to generate an image of the subject using a signal, wherein the probe is disposed in close proximity to or close to the subject and serves as a biological communication interface. A control signal for controlling the irradiation and detection of the light. The control signal includes a second biological transmission unit that is disposed in close proximity to or close to the subject and serves as a biological communication interface. The transmitted light intensity signal is transmitted and received between the first biological transmission means and the second biological transmission means by biological communication. Providing the body light measuring device.

  In addition, the probe irradiates the subject with irradiation light, detects the passing light from the subject, outputs an electrical signal corresponding to the passing light, and controls the light irradiation in the probe and outputs from the probe. A biological light measurement method in a biological light measurement apparatus comprising a control means for generating an image of the subject using the processed signal, wherein a control signal instructing the start of irradiation of the irradiation light is sent from the control means to the probe A control signal transmission step for transmitting to the subject by biological communication; an irradiation step for receiving the control signal and irradiating the subject with the irradiation light; and a signal conversion step for detecting the passing light and converting it to the electrical signal; An electric signal transmitting step for transmitting the electric signal to the control means by biometric communication; and a signal processing step for processing the electric signal. To provide a biological optical measurement wherein the.

  According to the present invention, the degree of freedom of measurement of the biological light measurement device can be increased by reducing the restraint of the subject regardless of the use environment, and the ease of use can be improved.

It is a block diagram for demonstrating schematic structure of the biological light measuring device of 1st embodiment. It is explanatory drawing for demonstrating the irradiation position of a biological light measuring device, a detection position, and arrangement | positioning of a measurement point. It is explanatory drawing for demonstrating the outline | summary of biometric communication. (A) And (b) is explanatory drawing for demonstrating the arrangement | positioning state of the biological light measuring device of 1st embodiment. It is a block diagram for demonstrating schematic structure of the biological light measuring device of 2nd embodiment. It is explanatory drawing for demonstrating the mounting state of the biological light measuring device of 2nd embodiment. (A) And (b) is explanatory drawing for demonstrating the other arrangement | positioning state of the biological light measuring device of embodiment of this invention.

<< First Embodiment >>
Hereinafter, a first embodiment to which the present invention is applied will be described. Hereinafter, in all the drawings for explaining the embodiments of the present invention, those having the same function are denoted by the same reference numerals, and repeated explanation thereof is omitted.

  In FIG. 1, the block diagram for demonstrating schematic structure of the biological light measuring device 100 of this embodiment is shown. The biological light measurement apparatus 100 according to the present embodiment includes a probe 120 attached to a subject 110 that is a living body, a control unit 130 that controls the entire apparatus, and a relay that relays signals between the probe 120 and the control unit 130. Unit 140, and a cable 150 that connects between the control unit 130 and the relay unit 140. Signals are transmitted and received between the probe 120 and the relay unit 140 by biometric communication.

  In accordance with a control signal 810 from the control unit 130, the probe 120 irradiates a predetermined position of the subject 110 with light having a predetermined wavelength (here, near-infrared light; hereinafter referred to as irradiation light) and also the target. Light that is reflected from the vicinity of the surface of the specimen 110 or passes through the subject 110 (hereinafter referred to as biological passing light) is detected and transmitted to the relay section 140. The light irradiation section 210, the light detection section 220, The probe-side biological transmission unit 230 and a power source 240 that supplies power to each unit of the probe 120 are provided.

  The light irradiation unit 210 irradiates the subject 110 with irradiation light that has been modulated differently according to the light irradiation position. The light irradiation unit 210 outputs n (n is a natural number) light sources (hereinafter, natural numbers) that output light of different wavelengths. Optical output element) 211 and a plurality of optical module circuits (hereinafter referred to as optical modules) 212 that respectively modulate the light output from the optical output element 211.

  The wavelength of the light output from the light output element 211 is determined by the spectral characteristics of the target substance in the living body. For example, when measuring oxygen saturation, blood volume, etc. from the concentration of oxygenated hemoglobin and deoxygenated hemoglobin, one or more wavelengths are selected from the wavelength range of 600 mm to 1,400 mm. For the light output element 211, for example, a semiconductor laser or a light emitting diode is used. The light output element 211 outputs light in accordance with a control signal 810 from the control unit 130, for example, a control signal for instructing irradiation start or irradiation stop (ON / OFF) and a control signal for instructing intensity.

  The optical module 212 includes an encoding circuit (modulation circuit), and modulates light output from the light output element 211 according to the irradiation position in accordance with a control signal 810 from the control unit 130. The light (irradiation light) output from each optical module 212 is irradiated to a plurality of regions of the subject 110 through or without an optical component such as an optical fiber. The light of n wavelengths output from the light output element 211 is optically mixed in a predetermined combination unit and then irradiated to the living body after modulation.

  The light detection unit 220 detects the light passing through the living body according to the control signal 810 from the control unit 130, converts it into an electrical signal (passing light intensity signal), and outputs it. The sensor 221, the amplification circuit 222, and A / D converter 223 and signal detection circuit 224 are provided.

  The sensor 221 is configured by a photodiode or the like, and the amount of electricity (electricity) corresponding to the amount of light passing through the living body, which is guided from a plurality of measurement locations of the subject 110 via the optical fiber or not. Signal) and output to the amplifier circuit 222. Note that the sensor 221 is not limited to a photodiode. For example, it may be a photoelectric conversion element such as a photomultiplier tube.

  The amplifier circuit 222 receives an electrical signal from the sensor 221 and amplifies the signal to an appropriate signal strength. The A / D converter 223 converts the output signal of the amplifier circuit 22 into a digital signal.

  The signal detection circuit 224 selectively detects a modulation signal for each wavelength and each light irradiation position, and separates an electric signal for each wavelength and each irradiation position. Then, the transmitted light intensity signals 820 corresponding to the number of measurement points are generated for each wavelength from the separated electrical signals. The signal detection circuit 224 includes, for example, a lock-in amplifier having more measurement points. The generated transmitted light intensity signal 820 is output to the outside of the probe 120 via the probe-side biological transmission unit 230 in a predetermined order.

  Here, the irradiation position of irradiation light, the detection position of transmitted light, and the arrangement of measurement points will be described. Irradiation positions and detection positions are alternately arranged in a matrix of an appropriate size such as 3 × 3, 4 × 4, or 3 × 5. FIG. 2 shows a case where they are arranged in 3 × 3 as an example. By arranging the irradiation position and the detection position in this way, and selectively detecting the passing light with different modulation according to the irradiation position, information on a continuous area between the detection position and the adjacent irradiation position can be obtained. Can do. The area is represented as a measurement point at an intermediate point between the irradiation position and the detection position. These measurement points correspond to the number of channels detected by the signal detection circuit 224. For example, when the irradiation position and the detection position are arranged in a 3 × 3 matrix shown in FIG. 2, the number of measurement points is 12, and optical measurement of 12 channels is performed.

  The probe-side biological transmission unit 230 is a biological communication interface, and includes electrodes and a communication circuit. A communication path for biometric communication is established between both transmission units when the subject 110 touches the probe-side biometric transmission unit 230 together with the relay unit-side biometric transmission unit 410 described later. For this reason, in this embodiment, this probe side biological transmission part 230 is arrange | positioned in the position which touches the subject 110. FIG.

  Note that the probe 120 irradiates near-infrared light to a predetermined position of the subject 110, detects biological passage light at the determined position, and transmits and receives signals through the biological communication with the relay unit 140. In order to perform, it has a shape that can be fixed to the subject.

  The relay unit 140 relays signal transmission / reception between the probe 120 and the control unit 130, and includes a relay unit side biological transmission unit 410 and a relay unit side transmission / reception unit 420.

  The relay unit side biometric transmission unit 410 is a biometric communication interface, and in this embodiment, an electrode is arranged at a position where the subject 110 is touched. The relay unit side transmission / reception unit 420 is an interface that transmits / receives a signal to / from the control unit 130 via the cable 150, and includes a communication circuit that transmits / receives a signal.

  The relay unit 140 receives the control signal 810 generated by the control unit 130 via the relay unit side transmission / reception unit 420 and sends the control signal 810 to the probe 120 via the relay unit side biological transmission unit 410. The transmitted light intensity signal 820 transmitted from the probe 120 is received via the relay unit side biological transmission unit 410 and transmitted to the control unit 130 via the relay unit side transmission / reception unit 420. Since the relay unit 140 transmits and receives signals to and from the probe 120 attached to the subject 110 through biological communication, the relay unit 140 has a shape that allows the subject 110 to contact and attach, or to adhere to the subject 110.

  The control unit 130 controls the overall operation of the biological light measurement apparatus 100 and performs various processes on the detected transmitted light intensity signal 820. The control unit 310, the signal processing unit 320, and the input / output interface (I) / F) 330, a control unit side transmission / reception unit 340, a storage unit 350, and a power supply 360 that supplies power to each unit in the control unit 130.

  The input / output interface 330 is an interface for inputting an instruction to the control unit 130 and outputting a processing result, to which a display device 370 and an operation device 380 are connected. Data generated in the control unit 130 is displayed on the display device 370, and instructions input via the operation device 380 are notified to each unit in the control unit 130.

  The operation control unit 310 controls the operation of each unit of the biological light measurement device 100 in accordance with an instruction input via the operation device 380. In the present embodiment, for example, a control signal 810 that gives instructions to the probe 120, such as measurement start, measurement end, output light intensity, modulation frequency, and probe placement, is generated, and light is irradiated on the living body. Control the detection. Also, an instruction is issued to the signal processing unit 320 to process the transmitted light intensity signal 820 transmitted from the probe 120.

  The control unit side transmission / reception unit 340 is an interface that transmits / receives signals to / from the relay unit 140 via the cable 150, and includes a communication circuit that transmits / receives signals. In the present embodiment, the control signal 810 is transmitted in accordance with an instruction from the operation control unit 310, and the transmitted light intensity signal 820 is received in a predetermined order.

  The signal processing unit 320 processes the passing light intensity signal 820 transmitted from the probe 120 under the control of the operation control unit 310, and generates various data. For example, the oxygenated hemoglobin concentration change, the deoxygenated hemoglobin concentration change, the total hemoglobin concentration change, and the like are calculated for each channel from the transmitted light intensity signal. At this time, filter processing or the like may be performed. The signal processing unit 320 also generates an image to be plotted on the two-dimensional image of the subject 110 from the calculation result. The generated various data is stored in the storage unit 350 and displayed on the display device 380 via the input / output interface 330.

  The control unit 130 includes a CPU and a memory, and each function of the control unit 130 is realized by the CPU loading a program held in the storage unit 350 into the memory and executing the program. Note that the storage unit 350 also stores data necessary for the signal processing unit 320, temporary data generated during various processes, and the like.

  As described above, in the present embodiment, transmission / reception of signals between the probe 120 and the relay unit 140 is performed by biological communication using the subject 110 as a transmission medium. Here, an outline of biometric communication will be described with reference to FIG.

  Biometric communication is a form of communication that uses a human body or the like as a conductor as a communication medium. As the transmission method, a current method, an electric field method, an electromagnetic wave method, and the like are known. Here, a current method will be described as an example.

  In the current method, a weak current of about several hundred μA flows through the living body when the living body touches both the transmission-side signal electrode and the receiving-side signal electrode. At this time, information is transmitted from the transmission-side signal electrode to the reception-side signal electrode by applying the modulation to the current.

  As shown in FIG. 3, when the living body 500 touches the receiving side signal electrode 520 connected to the receiving side terminal 530, the transmitting side terminal 510 disposed in close contact with the living body 500, the receiving side signal electrode 520, and A closed circuit is formed between the receiving terminal 530 and the ground. At this time, if a predetermined current is generated in the transmission side terminal 510, the current flows in the closed circuit. Biometric communication uses this current flow to perform data communication. At this time, as shown in the figure, the living body 500 stands on the ground, and the receiving terminal 530 is connected (grounded) to the ground.

  In this embodiment, when the subject 110 touches both the transmission / reception unit 230 of the probe 120 and the living body side relay transmission / reception unit 410 of the relay unit 140, a weak current flows on the surface of the subject 110, and signal transmission / reception is performed. Is called.

  As shown in FIG. 1, a control signal 810 transmitted from the control unit 130 to the light irradiation unit 210 is transmitted from the control unit side transmission / reception unit 340 to the relay unit side transmission / reception unit 420 via the cable 150, and relay unit side biological transmission is performed. The signal is transmitted from the unit 410 to the probe-side biological transmission unit 230 via the subject 110. On the other hand, the passing light intensity signal 820 detected by the light detection unit 220 is sent from the probe-side biological transmission unit 230 to the relay-side biological transmission unit 410 via the subject 110, and from the relay-unit-side transmission / reception unit 420 to the cable 150. To the control unit side transmitting / receiving unit 340.

  Each part of the living body light measurement device 100 of this embodiment explained above is arranged as shown in Drawing 4 (a), for example. That is, the probe 120 is disposed on the head of the subject 110, and the relay unit 140 is disposed on a handrail 710 of the walker 700 in this example, where the subject 110 can contact at the time of measurement. The control unit 130 is disposed outside the walker, and a cable 150 is wired between the repeater 140 and the control unit 130.

  Hereinafter, the operation | movement at the time of the measurement by the biological light measuring device 100 of this embodiment is demonstrated. Here, an example in which light of two or more wavelengths (here, for example, two wavelengths of 695 nm and 830 nm) corresponding to two types of measurement objects of oxygenated hemoglobin and deoxygenated hemoglobin is irradiated. I will explain.

  When receiving the instruction to start the inspection via the operation device 380, the operation control unit 310 generates and transmits a control signal 810 to the light irradiation unit 210 so as to start the output of the two wavelengths of light. At this time, the control signal 810 necessary for processing in the probe 120, such as the intensity of output light and the modulation frequency, is also generated and transmitted. The control signal 810 is transmitted from the control unit side transmission / reception unit 340 to the relay unit side transmission / reception unit 420 of the relay unit 140 via the cable 150.

  In the relay unit 140, the received control signal 810 is transmitted from the relay unit-side biological transmission unit 410 to the probe 120 through the subject 110 through biological communication.

  When the probe 120 receives the test start control signal 810 via the probe-side biological transmission unit 230, the light irradiation unit 210 corresponds to each wavelength in the optical module 212 until the test end control signal 810 is received. The modulated signal to be generated is generated, the signal is sent to the light output element 211, the light of these two wavelengths is synthesized and output, and the subject 110 is irradiated from a plurality of irradiation positions.

  In the light detection unit 220, the passing light is detected by the sensor 211, amplified by the amplification circuit 222, modulated into a digital signal by the A / D converter 223, and is measured for each measurement point and wavelength by the signal detection circuit 224. Modulation is performed and a hemoglobin amount change signal 820 is output as a transmitted light intensity signal. Here, in order to irradiate light of two wavelengths, a hemoglobin amount change signal (transmitted light intensity signal) 820 having the number of channels twice the number of measurement points is obtained.

  The hemoglobin amount change signal (transmitted light intensity signal) 820 detected by the signal detection circuit 224 is transmitted from the probe-side biological transmission unit 230 to the relay unit-side biological transmission unit 410 of the relay unit 140 via the subject 110. The relay unit 410 transmits the received hemoglobin amount change signal (transmitted light intensity signal) 820 from the relay unit side transmitting / receiving unit 420 to the control unit 130 via the cable 150.

  In the control unit 130, when an instruction to end the examination is received via the operation device 380, the operation control unit 310 generates a control signal 810 and sends the control signal 810 to the probe 120 via the relay unit 140, and the signal processing unit 320 performs control. Signal processing is performed on the hemoglobin amount change signal (transmitted light intensity signal) 820 received by the unit-side transmitting / receiving unit 340. Here, a graph showing, for each channel, oxygenated hemoglobin concentration change, deoxygenated hemoglobin concentration change, total hemoglobin concentration change, etc., from the hemoglobin amount change signal (transmitted light intensity signal) 820, and these information are obtained from the subject 110. Create image data plotted on a three-dimensional image.

  The created image data is stored in the storage unit 350 and displayed on the display device 370 via the input / output interface 330.

  As described above, according to the present embodiment, in the biological optical measurement device, transmission / reception of signals between the probe arranged near the living body and the apparatus main body (control unit) that performs various controls and signal processing is performed. This is performed by bio-communication using as a medium. That is, instead of using a conventional cable cable as a communication medium, a living body (subject) itself is used as a communication medium. Therefore, according to the present embodiment, since the living body can replace the cable, a living body optical measurement device having a probe to which the cable is not connected can be obtained.

  Since no cable is connected to the probe, according to the biological light measurement device of the present embodiment, the probe does not shift due to the weight of the cable. In addition, since the restraint on the subject is reduced, measurement can be performed in a more free state with no burden.

  In addition, since wireless communication is not performed, there is no adverse effect such as radio wave interference, and there is no security vulnerability with respect to transmission / reception data. Therefore, even in an environment where there are large restrictions on radio waves such as in hospitals, it can be used without taking complicated measures to eliminate radio wave interference with other devices.

  Therefore, according to the present embodiment, it is possible to provide a biological light measurement device with a high degree of freedom in the measurement environment, and the ease of use is improved.

  In the present embodiment, the case where the repeater 140 is arranged on the handrail of the walker is described as an example, but the arrangement position of the repeater 140 is not limited to this. For example, as shown in FIG. 4B, the repeater 140 may be arranged at a position where the head of the subject 110 on the bed contacts.

  In the present embodiment, the light detection unit 220 in the probe 120 generates a transmitted light intensity signal and transmits it to the control unit 130. However, the present invention is not limited to this. For example, it may be configured to transmit the light passing through the living body detected by the sensor 221 to the control unit 130 via, for example, an optical fiber. In this case, the A / D converter 223 and the signal detection circuit 224 are provided on the control unit 130 side. Moreover, you may transmit the biological body passage light to the control part 130 in the state after A / D conversion. In this case, the signal detection circuit 224 is provided on the control unit 130 side.

<< Second Embodiment >>
A second embodiment to which the present invention is applied will be described. In the present embodiment, the relay unit and the control unit are not connected by a cable. Hereinafter, the present embodiment will be described focusing on the configuration different from the first embodiment.

  FIG. 5 is a block diagram for explaining a schematic configuration of the biological light measurement apparatus 600 of the present embodiment. As shown in the figure, the biological light measurement apparatus 600 of the present embodiment includes a probe 120, a relay unit 640, and a data processing / display unit 630.

  Since the probe 120 of this embodiment has the same configuration as that of the first embodiment, it will not be described here.

  The relay unit 640 according to the present embodiment generates a control signal 810, transmits the control signal 810 to the probe 120 through biometric communication, and records a passing light intensity signal 810 transmitted from the probe 120 through biometric communication. Similar to the first embodiment, the relay unit 640 of the present embodiment includes a relay unit-side biological transmission unit 410 that is an interface for performing biological communication with the probe 120. Furthermore, the relay unit 640 of the present embodiment includes an operation control unit 430, a data recording unit 440, and an operation unit 450.

  The operation unit 450 is an interface that receives an instruction from the operator. The operation control unit 430 generates a control signal 810 to be transmitted to the probe 120 in accordance with an instruction received via the operation unit 450 and transmits the control signal 810 to the probe 120 via the relay unit side biological transmission unit 410.

  The data recording unit 440 records the passing light intensity signal 820 received via the relay unit side biological transmission unit 410. The data recording unit 440 includes, for example, a removable portable recording medium driving device, and records the received transmitted light intensity signal 820 to the inserted portable recording device. It may be configured by a storage device such as a hard disk. In this case, an interface capable of outputting data in the hard disk to an external device is provided.

  The data processing / display unit 630 includes a signal processing unit 320, an input / output interface (I / F) 330, a storage unit 350, a power supply 360, and a data reading unit 390. For example, a display device 370 and a scanning device 380 are connected to the input / output interface 330.

  The data reading unit 390 reads the transmitted light intensity signal 820 recorded in the data recording unit 440 of the relay unit 640 after completion of the measurement or at a predetermined timing. The read passage light intensity signal 820 is subjected to data processing similar to that of the first embodiment in the signal processing unit 320, and various image data is generated. The various generated image data is displayed on the display device 370 and stored in the storage unit 350 as in the first embodiment.

  Note that the relay unit 640 of the present embodiment also performs biometric communication using the subject 110 as a medium, as in the first embodiment, so that the relay unit-side biological transmission unit 410 can be in close contact with the subject 110. To do. Furthermore, in this embodiment, as shown in FIG. 6, the relay unit 640 has a shape to which the subject 110 can be attached.

  In the present embodiment, the relay unit 640 and the data processing / display unit 630 include a CPU, a memory, and a storage device, and the CPU loads each program stored in the storage device to the memory and executes the program. Realize the function.

  Also in the present embodiment, as in the first embodiment, the A / D converter 223 and the signal detection circuit 224 or the signal detection circuit 224 are provided on the relay unit 640 side or the data processing / display unit 630 side. It may be configured.

  As described above, according to the present embodiment, as in the first embodiment, transmission / reception of signals with the probe is performed by biological communication. Therefore, the same effect as the first embodiment can be obtained. Furthermore, according to the present embodiment, the relay unit and the control unit are not connected. Therefore, since the probe and the relay unit attached to the subject are independent from the device main body (control unit) to which the display device or the like is connected, a biological light measurement device with a higher degree of freedom can be provided.

  In this embodiment, the signal processing unit 320 is configured to be included in the data processing / display unit 630, but may be configured to be included in the relay unit 640. In this case, the relay unit 640 performs the generation of the in-vivo image. Therefore, since the data processing / display unit 630 only reads and displays image data generated in advance, the data processing / display unit 630 may be configured by a general-purpose information processing device.

  In each of the above embodiments, the case where the biometric communication between the probe 120 and the relay unit 140 (or 640) is performed by the current method has been described as an example, but the biometric transmission method is not limited thereto. For example, an electric field method, an electromagnetic wave method, or the like may be used.

  In the case of these methods, communication can be performed even if both the probe 120 and the relay unit side biological transmission unit 410 are not in contact with the subject 110. Therefore, for example, as shown in FIG. 7A, the relay unit 140 (or 640) may be arranged on the seat surface of the chair on which the subject 110 sits. Further, as shown in FIG. 7B, the relay unit 140 (or 640) may be arranged at a desired position on the bed on which the subject 110 lies.

DESCRIPTION OF SYMBOLS 100: Biological light measuring device, 110: Subject, 120: Probe, 130: Control part, 140: Relay part, 150: Cable, 210: Light irradiation part, 211: Light output element, 212: Optical module, 220: Light Detection unit, 221: sensor, 222: amplification circuit, 223: A / D converter, 224: signal detection circuit, 230: probe-side biological transmission unit, 240: power supply, 310: operation control unit, 320: signal processing unit, 330: input / output interface, 340: control unit side transmission / reception unit, 350: storage unit, 360: power supply, 370: display device, 380: operation device, 390: data reading unit, 410: relay unit side biological transmission unit, 420: Relay unit side transmission / reception unit, 430: operation control unit, 440: data recording unit, 450: operation unit, 500: living body, 510: transmission side terminal, 520: reception side signal electrode, 53 : The receiving terminal, 600: biological light measuring device, 630: data processing and display unit, 640: relay unit, 810: control signal 820: transmitted light intensity signals

Claims (9)

A probe that irradiates the subject with irradiation light and detects passing light from the subject, and outputs the probe as an electrical signal;
A living body measuring device and a control means for generating an image of the subject using the electric signal output from the probe to control the irradiation of light in the probe,
Wherein the probe comprises a first biological transmission means to be the arranged to close or proximate to a subject in vivo communication interface,
The control means includes second biological transmission means arranged to be in close proximity to or close to the subject and serving as a biological communication interface,
The control signal for controlling the irradiation and detection of the light and the electrical signal are transmitted and received by biological communication between the first biological transmission means and the second biological transmission means ,
The electrical signal, amplifies the transmitted light that has been converted to the passing light intensity signal, the biological light measuring device, wherein a signal der Rukoto converted into a digital signal. The biological light measurement device according to claim 1,
The probe is
A sensor that detects the passing light and converts it into the passing light intensity signal;
An amplifier circuit for amplifying the transmitted light intensity signal;
An A / D converter that converts the amplified transmitted light intensity signal into a digital signal.
A biological light measuring device characterized by the above . The biological light measurement device according to claim 1 or 2 ,
The control means includes
Processing means comprising operation control means for generating the control signal and signal processing means for generating the image from the electrical signal;
Relay means provided independently of the processing means;
A cable connecting the processing means and the relay means;
The biological light measuring device, wherein the second biological transmission means is provided in the relay means. The biological light measurement device according to claim 1 or 2 ,
The control means includes
Relay means comprising operation control means for generating the control signal and recording means for recording the electric signal;
A signal processing means for reading out the electrical signal recorded in the recording means and generating the image,
The biological light measuring device, wherein the second biological transmission means is provided in the relay means. The biological light measurement device according to claim 1 or 2 ,
The living body light measurement apparatus, wherein the control means has a shape that can be attached to the subject. The biological light measurement device according to claim 3 or 4 ,
The living body light measurement apparatus, wherein the relay means has a shape that can be attached to the subject. The biological light measurement device according to any one of claims 1 to 6 ,
The probe is
A light source that generates light of one or more wavelengths;
Modulation means that modulates light emitted from the light source according to an irradiation position and irradiates one or more irradiation positions as the irradiation light,
Electric signal output from the probe, the biological light measuring device, characterized in that after amplification after conversion to the digital signal, which is an electrical signal which is separated in the irradiated wavelength and each of the irradiation position. The biological light measurement device according to any one of claims 1 to 6 ,
The probe is
A light source that generates light of one or more wavelengths;
Modulation means that modulates light emitted from the light source according to an irradiation position and irradiates one or more irradiation positions as the irradiation light,
Electric signal output from the probe, the biological light measuring device, characterized in that an electrical signal before being separated into the irradiated wavelength and each of the irradiation position. A probe that irradiates the subject with irradiation light, detects passing light from the subject, outputs an electrical signal corresponding to the passing light, and controls light irradiation at the probe and is output from the probe a living body light measuring method in a biological optical measurement device and a control means for generating an image of said object using said electrical signal,
A control signal transmission step of transmitting a control signal instructing the start of irradiation of the irradiation light from the control means to the probe by biological communication;
An irradiation step of receiving the control signal and irradiating the subject with the irradiation light;
A signal converting step of detecting the passing light and converting it to the electrical signal;
An electrical signal transmission step of transmitting the electrical signal to the control means by biometric communication;
E Bei and a signal processing step of processing said electrical signal,
The electrical signal, amplifies the transmitted light that has been converted into transmitting light intensity signals, converted into digital signals, a biological optical measurement wherein the signal der Rukoto separated for each wavelength and for each irradiation position.

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