JP5527808B2 - Blood clotting time measurement device - Google Patents

Description

  The present invention relates to a blood coagulation time measuring device for measuring the time until blood coagulates.

An example of a technique for measuring the clotting time of blood taken out of the body is as follows. First, a steel ball is inserted into a test tube that can be moved up and down repeatedly by an elevating device, and the steel ball is floated to a certain height by being attracted by a magnetic force with a magnet arranged outside the test tube. A light source and a light receiving sensor are provided with a steel ball floating at a certain height. An appropriate amount of measurement blood is put into the test tube, and the test tube is repeatedly moved up and down. In a state where the measurement blood is not coagulated, the steel ball maintains a certain height by suction of the magnet. However, when the measurement blood coagulates, the resistance force by the blood is superior to the attraction force by the magnetic force of the magnet, and the steel ball cannot move up and down together with the blood and maintain a state of floating at a certain height. The light-receiving sensor detects that the steel ball is in a state where it cannot maintain a certain height, and the coagulation time of the measured blood is measured from the time elapsed so far. Such a technique is shown as a conventional technique in Japanese Patent No. 3461618.
Japanese Patent No. 3461618

In addition, US Pat. No. 5,372,946 includes a measuring device and a measuring container. The measuring blood is introduced into a measuring capillary provided in the measuring container and inserted into the measuring device, and an air pump provided in the measuring device is provided. A technique is disclosed in which blood to be measured is reciprocated in a measuring capillary by increasing or decreasing the pump pressure, and the blood coagulation time is measured from the change in time required for this reciprocating movement.
US Pat. No. 5,372,946

  The technique described in Patent Document 1 described above requires a lifting device for repeatedly moving the test tube up and down, and its structure is complicated. And since the dimensional accuracy such as the thickness of the test tube wall and the diameter of the steel ball has a great influence on the measurement accuracy of the blood coagulation time, a high accuracy is necessary and it is expensive. was there. Furthermore, in order to measure the coagulation time, there is a problem that the measurement blood needs to be so large that the steel ball floating at a certain height is submerged, and the measurement cannot be performed with a small amount of blood.

  Moreover, in the technique described in Patent Document 2, the air pump provided in the measuring device and the measuring capillary of the measuring container inserted in the measuring device need to be connected with an airtight structure. This is because if the air leaks without being connected with the airtight structure, the predetermined pump pressure cannot be increased or decreased, and naturally the time required for the reciprocating movement of the blood to be measured is different. A structure in which the air pump and the measurement capillary are connected by an airtight structure simply by inserting the measurement container into the measurement apparatus requires high dimensional accuracy in the shape of both the measurement apparatus and the measurement container.

  The present invention has been made in view of the circumstances of the prior art, and an object thereof is to provide a blood coagulation time measuring device having a simple structure. It is another object of the present invention to provide a blood coagulation time measuring apparatus that can accurately measure the blood coagulation time even with a small amount of blood.

In order to achieve such an object, the blood coagulation time measuring device of the present invention comprises a measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole. the measuring cartridge, measuring blood tube portion extending in the lateral direction of the communicating insertion direction is provided to it and measuring a blood inlet which upwardly opened which is turned on, the constriction in the middle and the front end portion of the narrow tube portion provided, both ends S pole and reciprocally movably disposed within a predetermined range a rod magnet in the insertion direction of the N pole, constriction side of the rod-shaped magnet the middle between the two constrictions in the narrow tube portion so as to close the stenosis to be in the in the measurement apparatus main body, the rod-shaped magnet of the middle suction by a magnetic force when said measurement cartridge is inserted into the cartridge insertion hole As in窄部side provided with means for closing the constriction, reciprocates the bar magnets of the measuring cartridge inserted into the cartridge insertion hole in the insertion direction by suction by the magnetic force to switch at a predetermined time interval Magnet reciprocating means for moving is provided, and magnet position detecting means for detecting a state in which light is blocked by the opaque bar magnet and the bar magnet is biased toward one end of the reciprocating movement is provided, and the magnet reciprocating means is provided. A discriminating means for discriminating whether or not the position of the rod-shaped magnet that is attracted and moved by the magnetic force is coincident with the position of the rod-shaped magnet actually detected by the magnet position detecting means; measuring time for measuring the time from the start of the reciprocating movement of the rod-shaped magnet by the magnet reciprocating means to the determining that the position of the rod-shaped magnet does not coincide with the discrimination means Means is provided, the time measured by said time measuring means is constituted by providing a display means for displaying the blood coagulation time of the measurement blood.

In addition, the measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole, the measurement cartridge has an upper portion opened to which measurement blood is introduced. A blood inlet for measurement and a narrow tube portion communicating with it and extending in the lateral direction of the insertion direction are provided , a narrowed portion is provided in the middle and at the tip of the narrow tube portion, and both end portions between the two narrowed portions in the narrow tube portion The S pole and N pole bar magnets are arranged so as to be reciprocally movable in a predetermined range in the insertion direction, and when the bar magnet is located on the middle narrow section side, the narrow section is closed. to, a means for closing the constriction as the measuring cartridge is the bar magnet to the constriction side of the middle suction by a magnetic force when being inserted into the cartridge insertion hole A magnet reciprocating means for reciprocating in the direction of insertion by suction by the magnetic force for switching the bar magnets of the measuring cartridge inserted into the cartridge insertion hole at a predetermined time interval is provided, the light shielding opaque the bar magnet And a magnet position detecting means for detecting a state where the bar magnet is biased toward one end of the reciprocating movement, and a position where the bar magnet should be moved by being attracted by the magnetic force of the magnet reciprocating means; The discriminating means for discriminating whether or not the positions of the bar magnets actually detected by the magnet position detecting means coincide with each other is provided, and the discriminating means is started when the reciprocating movement of the bar magnet by the magnet reciprocating means is started. the in the time since it is determined that the position of the bar-shaped magnets are matched up to determine the position of the rod-shaped magnet is not compatible with the determination means Provided time measuring means for constant, the time measured by said time measuring means may be constituted by providing a display means for displaying the blood coagulation time of the measurement blood.

Then, the insertion detection means for detecting which said measurement cartridge is pressed when to a predetermined position to be inserted in the cartridge insertion hole provided, the insertion of the measuring cartridge is detected by the insertion detection means, wherein You may comprise so that the reciprocation of the said bar-shaped magnet by a magnet reciprocation means may be started.

  Further, the time measuring means includes a timer, and starts the time measuring operation by the timer when the reciprocating movement of the bar magnet by the magnet reciprocating means, and the position of the bar magnet corresponds to the position of the discriminating means. If it is determined that there is not, the time counting operation may be stopped.

  The magnet reciprocating means includes an electromagnetic coil in which the measuring cartridge inserted into the cartridge insertion hole is loosely fitted, and an electromagnetic coil current control means for switching the direction of the current flowing through the electromagnetic coil at a predetermined time interval. You may comprise.

Further, the measurement cartridge is formed such that at least a portion for detecting the state where the bar magnet is biased toward one end of the reciprocating movement is formed transparent, the bar magnet is formed opaque, and the magnet position detecting means is opaque. The rod-shaped magnet is composed of a light source disposed so as to face a portion detecting the state of being biased toward one end side where the rod-shaped magnet is reciprocated, a light receiving sensor, and a light receiving detection means to which a signal of the light receiving sensor is given. You may do it.

A position setting magnet for attracting the bar magnet is provided near the opening of the cartridge insertion hole, and when the measurement cartridge is inserted into the cartridge insertion hole, the position setting magnet is attracted by the magnetic force of the position setting magnet. The rod-shaped magnet may be positioned on the middle narrow portion in the narrow tube portion so as to close the narrow portion .

In addition, the first click means for holding the state where the measurement cartridge is inserted to a predetermined position of the cartridge insertion hole, and the second state for holding the state where the measurement cartridge is half inserted into the cartridge insertion hole. A click means is provided, and is attracted by the magnetic force of the position setting magnet while being held by the second click means, and the bar magnet is positioned on the middle narrow portion in the narrow tube portion to close the narrow portion. It is also possible to configure so that the measurement blood can be introduced into the measurement blood introduction port while being closed and held by the second click means.

And further, when the measuring cartridge into the cartridge insertion hole is inserted, with the electromagnetic coil current control means, the constriction in front Symbol rod-shaped magnet positioned in the narrowed portion side of the middle in the narrow tube portion It can also comprise so that an electric current may be sent through the said electromagnetic coil so that it may run side by side .

The blood coagulation time measuring device of the present invention comprises a measuring device main body having a cartridge insertion hole provided in the lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole. A measurement blood input port having an open upper portion into which measurement blood is input and a narrow tube portion communicating with the measurement blood and extending in the lateral direction of the insertion direction are provided, and a narrowed portion is provided in the middle and the distal end portion of the thin tube portion. A steel ball or a rod-shaped steel body is disposed between the two narrowed portions so as to be reciprocally movable in a predetermined range in the insertion direction, and the narrowed portion is closed when the steel body is on the middle narrowed portion side. to the to the measuring device main body, the constriction closed as the measuring cartridge is in constriction portion in the middle the suction the steel body by a magnetic force when being inserted into the cartridge insertion port Means for providing, by disposing the respective first electromagnetic coil and a second electromagnetic coil on the opposite ends of the reciprocating movement of the steel body of the measuring cartridge inserted into the cartridge insertion hole, and the first electromagnetic coil said steel member reciprocating means for reciprocating the steel body in the insertion direction at a predetermined time interval is provided by applying a current to alternating suction by a magnetic force at a second predetermined electromagnetic coil time interval, opaque the steel body The steel is moved by being attracted and moved by the magnetic force of the steel body reciprocating means, provided with a steel body position detecting means for detecting a state where the light is blocked and the steel body is biased toward one end of the reciprocating movement. discrimination means for discriminating whether the actually detected position of the steel body body position to a and in the steel body position detecting means is coincident provided, reciprocating the steel body by the steel body reciprocating means The discrimination means from the start of movement More provided time measuring means for measuring the time until the position of the steel body it is determined that no match, the display means for displaying the measured time by the time measuring means as a blood coagulation time of the measurement of blood It is also possible to provide it.

In addition, the measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole, the measurement cartridge has an upper portion opened to which measurement blood is introduced. A blood inlet for measurement and a narrow tube portion communicating with it and extending in the lateral direction of the insertion direction are provided, a narrow portion is provided in the middle and at the tip of the narrow tube portion, and a steel ball is provided between the two narrow portions in the narrow tube portion or steel body of the rod-like arranged reciprocally moved at a predetermined range in the direction of insertion, when the steel body is the constriction side of the middle the so for closing the constriction, the measuring device main body, the means for closing the constriction provided measuring cartridge the steel body as in constriction side of the middle suction by a magnetic force when being inserted into the cartridge insertion hole, the cartridge By disposing the inserted respectively first electromagnetic coil and a second electromagnetic coil on the opposite ends of the reciprocating movement of the steel body of the measuring cartridge into the insertion hole, predetermined in the second electromagnetic coil and the first electromagnetic coil said steel member reciprocating means for reciprocating in the insertion direction is provided, wherein the light is blocked by the opaque the steel body the steel body by suction by the magnetic force by applying a current alternately at predetermined time intervals in the time interval the steel body position detecting means for detecting a state in which the steel body is biasing the one end of the reciprocating provided, wherein a position where a the steel member to be moved are attracted by the magnetic force of the steel body reciprocating means A discriminating means for discriminating whether or not the position of the steel body actually detected by the steel body position detecting means coincides is provided, and the discriminating is started when the reciprocating movement of the steel body by the steel body reciprocating means is started. position of the steel body is matched with means Doo is determined time measuring means for measuring the time until determining that the position of the steel body is not matched by the discriminating means is provided from the measured time by the time measuring means and the measured blood It is also possible to provide a display means for displaying the blood coagulation time.

3. The blood coagulation time measuring apparatus according to claim 1 or 2, wherein the measuring apparatus main body is provided with a rod-like magnet which is reciprocally movable in a thin tube portion of a measuring cartridge inserted in the measuring apparatus main body. Since the moving means reciprocates by a magnetic force at a predetermined time interval, a complicated mechanical device such as the lifting device of Patent Document 1 is not required. Moreover, high dimensional accuracy is not required, such as connecting the measuring device and measuring container of Patent Document 2 to an airtight structure. Therefore, the blood coagulation time measuring apparatus of the present invention has a simple structure and can be constructed at a low cost as a whole, and can be manufactured at a very low cost, especially if the measurement cartridge is mass-produced with a resin material or the like. It is. A narrowing portion is provided in the middle of the narrow tube portion, and when the measuring cartridge is inserted into the cartridge insertion hole, the rod-like magnet is attracted by magnetic force so as to be on the narrowing portion side in the middle so as to close the narrowing portion. since the amount of blood required for measurement is sufficient with a small amount of input is obtained Rudake from measuring the blood inlet port to the stenosis midway in the narrow tube portion of the measuring cartridge. Moreover, the blood does not overflow from the measurement blood inlet due to the reciprocating movement of the rod-shaped magnet.

In the blood coagulation time measuring apparatus according to claim 3, when the measuring cartridge into which blood has been introduced is inserted into the measuring apparatus body to a predetermined position, it is pressed and detected by the insertion detecting means, and the reciprocating magnet movement The reciprocating movement of the bar-shaped magnet is started by the means and the time measurement is started by the time measuring means. Therefore, the measurement is automatically started by inserting the measurement cartridge, and the measurement work is easy.

  In the blood coagulation time measuring device according to claim 4, the timer starts the time counting operation by the start of the reciprocating movement of the bar magnet by the magnet reciprocating means, and the position of the bar magnet by the discriminating means corresponds. If it is determined that the timer is not present, the timer operation is stopped, so that the time can be easily measured.

  In the blood coagulation time measuring device according to claim 5, the electromagnetic coil in which the inserted measurement cartridge is loosely fitted, and the electromagnetic coil current control means for switching the direction of the current flowing through the electromagnetic coil at a predetermined time interval Thus, since the magnet reciprocating means is constituted, the structure for reciprocating the bar magnet is simple, and the reciprocating movement can be easily controlled by current control.

In the blood coagulation time measuring device according to claim 6, since the state where the opaque rod-shaped magnet reciprocating is biased toward one end is detected by the light source and the light receiving sensor, is the rod-shaped magnet biased? Whether or not can be detected with a simple structure.

In the blood coagulation time measuring apparatus according to claim 7, since the position setting magnet for attracting the rod-shaped magnet is provided near the opening of the cartridge insertion hole, the measurement cartridge is inserted into the cartridge insertion hole. In addition, since the rod-shaped magnet is located on the middle of the narrow tube portion and closes the narrow tube portion, the amount of measurement blood that can be introduced into the narrow tube portion is small and constant. In addition, the measurement blood does not overflow from the narrow tube portion to the measurement blood inlet side due to the start of reciprocation of the rod-shaped magnet.

  9. The blood coagulation time measurement apparatus according to claim 8, wherein the first click means for holding the measurement cartridge inserted into a predetermined position of the cartridge insertion hole and the measurement cartridge is inserted into the cartridge insertion hole by about half. Since the second click means for holding the held state is provided, the blood to be measured can be introduced into the measurement cartridge while being held by the second click means, and the state inserted to the predetermined position can be It can be held securely.

In the blood coagulation time measuring apparatus according to claim 9, when a measuring cartridge is inserted into the cartridge insertion hole, a bar-shaped magnet is attached to the electromagnetic coil by the electromagnetic coil current control means toward the constricted part in the narrow tube part. Since the current is made to flow so as to be positioned, the position setting magnet as in the sixth aspect is not required, and the cost can be reduced accordingly.

12. In any of the blood coagulation time measuring devices according to claim 10 or 11, a steel ball or a rod-shaped steel body is disposed in the narrow tube portion of the measuring cartridge so as to be reciprocally movable in a predetermined range in the insertion direction. A first electromagnetic coil and a second electromagnetic coil are arranged in the main body at both ends of the reciprocating movement of the steel body of the measurement cartridge, and current is alternately supplied to the first electromagnetic coil and the second electromagnetic coil at predetermined time intervals. Since the steel body reciprocating means for reciprocating the steel ball or the rod-shaped steel body in the insertion direction at a predetermined time interval by the magnetic force suction is provided, the rod-shaped magnet as in the first aspect is not required, and this rod-shaped A steel ball or a rod-shaped steel body is cheaper than a magnet, and a measurement cartridge can be manufactured at a lower cost. In addition, a narrowed portion is provided in the middle of the narrow tube portion so that when the measuring cartridge is inserted into the cartridge insertion hole, the steel body is close to the narrowed portion in the middle by suction by magnetic force so as to close the narrowed portion. Therefore, the amount of blood necessary for the measurement is small enough to be introduced from the measurement blood inlet to the narrowed portion in the narrow tube portion of the measurement cartridge. Moreover, the blood does not overflow from the measurement blood inlet due to the reciprocating movement of the steel body.

  Hereinafter, a first embodiment of a blood coagulation time measuring apparatus according to the present invention will be described with reference to FIGS. FIG. 1 is an external perspective view of a first embodiment of a blood coagulation time measuring apparatus according to the present invention, where (a) shows a state before a measuring cartridge is inserted into a measuring apparatus body, and (b) shows a measuring apparatus. A state in which about half of the measurement cartridge is inserted into the main body is shown, and (c) shows a state in which the measurement cartridge is completely inserted into the main body of the measurement apparatus. 2A and 2B are structural views of the measurement cartridge, wherein FIG. 2A is a plan view, FIG. 2B is a left side view, FIG. 2C is a front view, and FIG. FIG. 3A and 3B are structural views of a measurement unit built in the measurement apparatus main body, wherein FIG. 3A is a plan view, FIG. 3B is a right side view, and FIG. 3C is a BB cross section of FIG. It is an arrow view, (d) is CC sectional view arrow view of (b). FIG. 4 is a cutaway plan view in which the measurement cartridge is inserted into the measurement unit of the measurement apparatus main body, (a) is a diagram showing a state in which the measurement cartridge is inserted approximately half, and (b) is the measurement cartridge. It is a figure of the state which inserted completely. FIGS. 5A and 5B are diagrams showing a state in which the measurement blood is put into the measurement cartridge. FIG. 5A shows a state immediately before the measurement blood is put in, and FIG. 5B shows a state in which the measurement blood is put in. FIG. 6 is a functional block diagram. FIG. 7 is a flowchart. FIG. 8 is a time chart when the blood coagulation time is 40 seconds as an example. FIG. 9 is a time chart when the blood coagulation time is 50 seconds as another example.

  In the first embodiment, the blood coagulation time measuring device of the present invention can be inserted into the measuring device main body 10 having the cartridge insertion hole 12 provided in the lateral direction as shown in FIG. And a measuring cartridge 14. The measuring apparatus main body 10 is provided with a power switch 16 provided on the outer surface of the apparatus main body and a display 18 including LEDs and the like. The measurement cartridge 14 is provided with a measurement blood inlet 20 for introducing measurement blood into the cartridge. Then, as shown in FIG. 1 (b), an appropriate amount of measurement blood is introduced into the measurement blood inlet 20 with the measurement cartridge 14 inserted approximately halfway into the cartridge insertion hole 12 of the measurement apparatus body 10. . Further, as shown in FIG. 1C, the measurement cartridge 14 is completely inserted into the cartridge insertion hole 12 of the measurement apparatus main body 10 until the insertion is restricted. The dimensions of the measuring apparatus main body 10 are, for example, a length of 150 mm, a width of 80 mm, and a height of 44 mm, and the measurement cartridge 14 has a length of 65 mm, a width of 20 mm, and a thickness of 6 mm.

The measuring cartridge 14 shown in FIG. 2 is composed of a distal end narrow diameter portion 14a having a thin outer diameter on the distal end side and a flat portion 14b having a thin and wide width on the upper and lower sides on the rear end side. A measuring blood inlet 20 having an upper opening is provided at the approximate center of the flat portion 14b. A thin tube portion 14c that communicates with the measuring blood inlet 20 and extends in the insertion direction in the lateral direction is formed in the thin tube portion 14c. Provided. Narrow portions 14d and 14d are provided in the middle and the distal end of the narrow tube portion 14c, and the distal end of the narrow tube portion 14c is opened at the distal end of the distal narrow diameter portion 14a. Between the two constricted portions 14d and 14d, a rod-like magnet 22 whose both ends are magnetized to the S pole and the N pole is disposed in the narrow tube portion 14c so as to be reciprocally movable between the two constricted portions 14d and 14d. Yes. In the state where the rod-shaped magnet 22 is located on the middle narrowed portion 14d side in the narrow tube portion 14c, the rod-shaped magnet 22 is configured to block the middle narrowed portion 14c. Further, a peripheral wall 14e is provided around the measurement blood inlet 20 so as to be slightly above the surface of the flat portion 14b so that the measurement blood does not spill around. Further, spherical recesses 14f and 14f are provided on the upper surface and the lower surface on the rear end side of the flat portion 14b, respectively, so that the measuring cartridge 14 can be easily pulled out of the measuring apparatus main body 10 and pulled out. Further, click concave grooves 14g and 14g are provided on the outer wall on one side of the flat portion 14b. As an example, the measurement cartridge 14 having such a structure can be manufactured at low cost by bonding parts formed by resin molding with a transparent resin and divided into upper and lower parts with a bar-shaped magnet 22 interposed therebetween.

  The measurement apparatus main body 10 incorporates a measurement unit 24 shown in FIG. The measurement portion 24 is provided with an insertion hole 24a that communicates with the cartridge insertion hole 12 in the disposed state and into which both the tip small diameter portion 14a and the flat portion 14b of the measurement cartridge 14 can be inserted. A limit switch 26 serving as an insertion detecting means is provided so as to be pressed at the tip of the tip small diameter portion 14a in a state where the measurement cartridge 14 is inserted. In addition, an electromagnetic coil 28 is provided so that the distal end small diameter portion 14a is loosely fitted, and a light source 30 and a light receiving sensor 32 are further disposed across the distal end side of the distal end small diameter portion 14a. Here, the measurement cartridge 14 may be at least transparent at the position facing the light source 30 and the light receiving sensor 32 in the inserted state, and the bar magnet 22 is configured to be opaque. The measurement unit 24 is provided with a heater 34 and a temperature sensor 36. Further, a position setting magnet 38 is provided at a position close to the opening of the insertion hole 24a. In addition, plungers 40 and 40 are disposed at positions where they are engaged with the two concave grooves 14g and 14g, respectively, in a state where the measurement cartridge 14 is completely inserted, and the insertion state of the measurement cartridge 14 is maintained. . The interval at which the two concave grooves 14g and 14g are provided and the interval at which the two plungers 40 and 40 are provided are naturally the same. Then, in a state where the measurement cartridge 14 is inserted approximately half, one plunger 40 is engaged with one concave groove 14g, and the approximately half inserted state is maintained. The concave grooves 14g, 14g and the plungers 40, 40 constitute a click means.

When the measuring cartridge 14 is inserted into the measuring section 24 having such a structure, as shown in FIG. 4A, first, an insertion hole 24a is opened in one concave groove 14g provided on the distal end small diameter section 14b side of the flat section 14b. One plunger 40 on the side is engaged, and the second click means is held in an approximately half-inserted state. In a state in which about half of this is inserted, the rod-like magnet 22 in the narrow tube portion 14c is biased toward the constricted portion 14c in the middle by being attracted by the magnetic force by the position setting magnet 38 provided on the opening side of the insertion hole 24a. In position. Then, in a state in which approximately half is inserted, the measurement blood inlet 20 of the measurement cartridge 14 is outside the measurement apparatus main body 10, and the measurement blood 42 is inserted into the measurement blood inlet 20 as shown in FIG. Can be input. As shown in FIG. 5 (b), the introduced measurement blood 42 is in a state where the constricted portion 14c in the middle is closed by the rod-shaped magnet 22, so that it flows into the constricted portion 14c and a small amount is sufficient.

  When the measuring cartridge 14 is completely inserted into the measuring unit 24, as shown in FIG. 4B, two plungers 40, 40 are respectively provided in the two concave grooves 14g, 14g provided in the flat portion 14b. And the fully inserted state as the first click means is maintained. In this fully inserted state, the distal end narrow diameter portion 14a is inserted into the electromagnetic coil 28, and the electromagnetic coil 28 is located at the approximate center of the two narrowed portions 14d and 14d of the narrow tube portion 14c. In addition, since the light source 30 and the light receiving sensor 32 are disposed so as to sandwich the distal end side of the distal narrow diameter portion 14a, the rod-shaped magnet 22 in the narrow tube portion 14c is biased toward the narrowed portion 14d on the distal end side. In this state, the light from the light source 30 is blocked by the bar-shaped magnet 22 so that the light receiving sensor 32 cannot receive light. In addition, when the measurement cartridge 14 is completely inserted, the limit switch 26 is pressed by the tip of the tip small diameter portion 14a, and it is detected that the measurement cartridge 14 is completely inserted.

In the blood coagulation measuring apparatus according to the present invention, the rod-shaped magnet 22 is reciprocated by the electromagnetic coil 28 in the narrow tube portion 14c, and the rod-shaped magnet 22 moves in the narrow tube portion 14c when the measured blood 42 is not solidified. When the measurement blood 42 is coagulated, the rod-shaped magnet 22 cannot move in the thin tube portion 14c. Therefore, the position of the rod-shaped magnet 22 is detected by the light receiving sensor 32 to determine whether the measurement blood 42 is coagulated. Is. Such a measurement operation is controlled by a microcomputer 44 as shown in FIG. When the microcomputer 44 detects that the measurement cartridge 14 has been completely inserted by a signal from the limit switch 26 serving as an insertion detection means, the current applied to the electromagnetic coil 28 is appropriately switched and controlled to control the bar magnet 22. The time measuring means 50 including the electromagnetic coil current control means 46 for starting the reciprocal movement of the motor and the timer 48 for starting the time measuring operation by the signal of the limit switch 26 is provided. In addition, a light receiving detection means 52 is provided for receiving a signal from the light receiving sensor 32 and outputting a signal corresponding to the position of the bar magnet 22. A discriminating means 54 for discriminating whether or not the polarity of the current applied to the electromagnetic coil 28 by the electromagnetic coil current control means 46 and the position of the bar magnet 22 detected by the light receiving detection means 52 is appropriate is provided. If it is determined that they are not coincident with each other, the signal is given to the time measuring means 50, and the time counting operation of the timer 48 is stopped. Then, a signal corresponding to the time measured by the time measuring means 50 is given to the display means 56, and the display means 56 displays the measurement time as a blood coagulation time by the indicator 18 such as an LED. The electromagnetic coil 28 and the electromagnetic coil current control means 46 constitute a magnet reciprocating means. The light source 30, the light receiving sensor 32, and the light receiving detecting means 52 constitute a magnet position detecting means.

  As an example, the electromagnetic coil current control means 46 reciprocates the bar magnet 22 by switching the polarity of the current applied to the electromagnetic coil 28 at intervals of 10 seconds. Further, the light receiving detection means 52 is such that the rod-shaped magnet 22 is on the flat portion 14b side of the measurement cartridge 14 when the light receiving sensor 32 receives light, and is on the distal end side of the distal end small diameter portion 14a when it is blocked from receiving light. To detect. The discriminating means 54 detects the position of the bar-shaped magnet 22 to be positioned according to the polarity of the current applied to the electromagnetic coil 28 by the electromagnetic coil current control means 46 and the bar-like shape detected by the light receiving detection means 52 based on the signal from the light receiving sensor 32. If the position of the magnet 22 corresponds, the measurement blood 42 is not yet coagulated, and if the position does not correspond, it is determined that the measurement blood 42 is coagulated. In this determination, even when the polarity of the current applied to the electromagnetic coil 28 is switched by the electromagnetic coil current control means 46, the rod-shaped magnet 22 is immediately brought into contact with the viscosity etc. even if the measurement blood 42 is not yet coagulated. It cannot move to the corresponding position. Therefore, it is necessary to determine the position of the bar-shaped magnet 22 to be positioned and the signal of the light receiving detection means 52 in consideration of the delay of the movement of the bar-shaped magnet 22. As an example, the determination may be made after an appropriate time (for example, 2 to 4 seconds) has elapsed since the polarity of the current applied to the electromagnetic coil 28 is switched. The display means 56 not only displays the blood coagulation time, but also receives a signal from the temperature sensor 36, and when the power switch 16 is turned on and the heater 34 is activated to bring the measuring unit 24 to 37 ° C., the display unit 56 displays. 18 displays “preparation OK”. The heater 34 is ON / OFF controlled by the temperature controller 58 based on a signal given from the temperature sensor 36 and operates so that 37 ° C. is always detected and maintained by the temperature sensor 36. Further, the light source 30 is energized when the power switch 16 is turned on and emits light.

  The operation of the blood coagulation time measuring apparatus of the present invention will be described with reference to FIG. First, when the power switch 16 is turned on, the heater 34 is energized to heat the measuring unit 24 (step 1). When the temperature sensor 36 detects that the temperature of the measuring unit 24 has risen to 37 ° C. due to this heating (step 2), the detection signal is given to the display means 56 of the microcomputer 44, and “ready” “OK” is displayed to indicate that measurement is possible (step 3). Thereafter, the temperature of the measuring unit 24 is detected by the temperature sensor 36, and the signal is given to the temperature controller 58. When the temperature is below 37 ° C, the power supply to the heater 34 is turned on, and the temperature is over 37 ° C and 37 ° C or higher. Then, the power supply to the heater 34 is turned off, and 37 ° C is always maintained. Then, after “Preparation OK” is displayed on the display 18, the measurement cartridge 14 is inserted into the measurement apparatus main body 10 approximately half and the measurement blood 42 is introduced into the measurement blood inlet 20. Here, the bar-shaped magnet 22 is biased to the narrowed portion 14d on the flat portion 14b side, and the blood to be measured 42 flows only to the narrowed portion 14d on the flat portion 14b side as shown in FIG. 5B. . After the measurement blood 42 is introduced, when the measurement cartridge 14 is further inserted and completely inserted until the limit switch 26 is pressed, this insertion is detected by the limit switch 26 (step 4), and the signal is sent to the microcomputer 44. Are provided to the electromagnetic coil current control means 46 and the time measuring means 50. The electromagnetic coil current control means 46 is provided with the bar magnet 22 on the electromagnetic coil 28 on the side where the light receiving sensor 32 is disposed on the distal end side of the small diameter portion 14a. A positive polarity current is applied so as to be attracted by a magnetic force, and a time counting operation by the timer 48 is started (step 5). Then, when the electromagnetic coil 28 is energized with + polarity, the bar magnet 22 is attracted and moved to the side where the light receiving sensor 32 is disposed, and the light received by the light receiving sensor 32 is blocked by the bar magnet 22, and the signal is The bar-shaped magnet 22 is detected by giving it to the light receiving detection means 52 (step 6). Here, the signal that the electromagnetic coil current control means 46 supplies a positive polarity current and the signal that the light receiving detection means 52 detects the bar magnet 22 are given to the discrimination means 54, and the bar magnet 22 should be present by energization. It is determined whether or not the position coincides with the position of the bar magnet 22 actually detected. At this time, if they do not coincide with each other, a signal is given from the discrimination means 54 to the display means 56, and the display means 56 displays an error on the display 18 (step 7). This is because if the rod-shaped magnet 22 is not detected, there is a possibility that the measurement blood 42 has already been coagulated, and measurement cannot be performed normally. When the electromagnetic coil current control means 46 starts energization and switches the polarity of energization, the movement of the bar-shaped magnet 22 moves with a delay due to the viscosity of the measurement blood 42 and the like. Therefore, it goes without saying that the determination means 54 is set so as to compare and determine the signal from the electromagnetic coil current control means 46 and the signal from the light reception detection means 52 in consideration of the delay of the movement of the bar-shaped magnet 22.

  If the bar magnet 22 is normally detected in step 6, the discriminating means 54 determines that the position where the bar magnet 22 should be and the position of the bar magnet 22 actually detected by energization coincide with each other. A signal is given to the means 46, and as an example, 10 seconds is waited (step 8). The electromagnetic coil current control means 46 switches the current so that the bar-shaped magnet 22 moves to the flat portion 14b side to the electromagnetic coil 28, thereby producing a -polar current. Energize (step 9). If the measurement blood 42 is not yet coagulated, the bar magnet 22 moves and the light receiving sensor 32 receives light. Therefore, the light receiving detection means 52 determines that the bar-shaped magnet 22 is not detected (step 10), and the determination means 54 determines that the polarity of energization matches the position of the bar-shaped magnet 22. Therefore, after waiting for 10 seconds (step 11), the electromagnetic coil current control means 46 again switches the current to energize the electromagnetic coil 28 with a positive polarity current (step 12). When the current is switched, the bar-shaped magnet 22 moves, and the light-receiving sensor 32 is cut off and the bar-shaped magnet 22 is detected (step 13). Then, the process returns to step 8, and in step 10 or step 13, the discriminating means. 54 is repeated until it is determined that the polarity of energization does not match the position of the bar-shaped magnet 22. If it is determined in step 10 or step 13 that the polarity of energization does not match the position of the rod-shaped magnet 22, the signal is given to the time measuring means 50, and the time counting operation of the timer 48 is stopped ( Step 14). The time measured is given to the display means 56 and displayed as a blood coagulation time on the display 18 (step 15), and the operation is terminated.

  An example of such an operation will be described with reference to a time chart shown in FIG. First, when the power switch 16 is turned on, the temperature of the measurement unit 24 of the measurement apparatus main body 10 is raised from room temperature to 37 ° C. by the heater 34, and measurement is possible (a). Since the blood coagulation time is greatly affected by temperature, the measurement is performed at 37 ° C., which is close to human body temperature. When about half of the measurement cartridge 14 is inserted, the measurement blood 42 is inserted into the measurement cartridge 14, and when the measurement cartridge 14 is completely inserted and the limit switch 26 is turned on (b), the electromagnetic coil 28. And the polarity is switched every 10 seconds (c). Then, in accordance with the polarity of the current flowing through the electromagnetic coil 28, the bar magnet 22 is moved in the narrow tube portion 14c of the measurement cartridge 14 to the distal end side of the distal narrow diameter portion 14a and the flat portion 14b side every 10 seconds. (D). Depending on the movement position of the bar-shaped magnet 22, the light receiving sensor 32 receives light or blocks light reception (e), and the signal is given to the light reception detecting means 52 to detect the position of the bar-shaped magnet 22. Here, when the blood to be measured 42 has not yet solidified, the rod-shaped magnet 22 has a distal end side and a flat portion of the distal end small diameter portion 14a in the narrow tube portion 14c according to the polarity of the current supplied to the electromagnetic coil 28. When the measurement blood 42 is coagulated, the rod-shaped magnet 22 moves to the distal end side of the distal end small diameter portion 14a in the narrow tube portion 14c in accordance with the polarity of the current supplied to the electromagnetic coil 28. It becomes impossible to move to the flat portion 14b side. Therefore, when the limit switch 26 is turned on and the measurement is started, the timer 48 starts timing, and when the energization of the electromagnetic coil 28 does not correspond to the position of the bar magnet 22, the timer 48 stops the timing operation ( f) The clotting time of the measurement blood 42 can be measured. In FIG. 8, the blood to be measured coagulates after 30 seconds have elapsed from the start of measurement, and the polarity of the current applied to the electromagnetic coil 28 is switched when 40 seconds have elapsed from the start of measurement. The magnet 22 cannot move, and the shift of this position is detected by the light receiving sensor 32. Therefore, in the operation of FIG. 8, a measurement result is obtained that the measurement blood 42 is coagulated in 40 seconds. The interval at which the rod-shaped magnet 22 is reciprocated is set to 10 seconds, since blood coagulation gradually proceeds. Therefore, even if the rod-shaped magnet 22 is reciprocated at a very short interval, the measurement accuracy does not become high and is practically necessary. It is set to measure the blood clotting time with a certain accuracy. Therefore, the reciprocating movement of the bar magnet 22 is not limited to being performed at intervals of 10 seconds.

  Further, another example of the operation of the present invention will be described with reference to a time chart shown in FIG. In the time chart shown in FIG. 9, the blood to be measured coagulates after 40 seconds from the start of measurement, and the polarity of energization to the electromagnetic coil 28 is switched when 50 seconds have passed from the start of measurement. Nevertheless, the bar-shaped magnet 22 cannot move, and this positional shift is detected by the light receiving sensor 32. Therefore, in the operation of FIG. 9, a measurement result is obtained that the measurement blood 42 is coagulated in 50 seconds.

  Next, a second embodiment of the blood coagulation time measuring apparatus of the present invention will be described with reference to FIGS. FIG. 10 is a functional block diagram of a second embodiment of the blood coagulation time measuring apparatus of the present invention. FIG. 11 is a flowchart of the second embodiment. 10 and 11, members and operations that are the same as or equivalent to those shown in FIGS. 1 to 9 are given the same reference numerals, and redundant descriptions are omitted.

  In the functional block diagram of the second embodiment shown in FIG. 10, the difference from the first embodiment is that the electromagnetic coil current control is performed when it is detected by the signal of the limit switch 26 that the measurement cartridge 14 is completely inserted. When a signal is given to the means 46 and the reciprocating movement of the bar-shaped magnet 22 is started, and it is determined by the determining means 54 that the position of the bar-shaped magnet 22 is appropriate, the time measuring means 50 is changed from the determining means 54. The timer 48 starts the timing operation. Therefore, when the determination unit 54 determines that the position of the bar-shaped magnet 22 is appropriate after the limit switch 26 is turned on and the bar-shaped magnet 22 is moved by the electromagnetic coil current control unit 46, the timer 48 responds to the signal. When the time counting operation is started and the determining means 46 determines that the position of the bar-shaped magnet 22 is not appropriate, the time measuring operation is stopped according to the signal. In this second embodiment, the signal for the timer 48 to start the timing operation is started by a signal from the determination means 54, unlike the first embodiment.

  Therefore, as shown in the flowchart of FIG. 11, when the limit switch 26 is turned on (step 4), the electromagnetic coil control means 46 supplies a current of + polarity to the electromagnetic coil (step 5-1), and the bar-shaped magnet 22 is supplied. Is moved to the distal end side of the distal end small diameter portion 14a of the measuring cartridge 14, and this position of the bar magnet 22 is detected by blocking light reception of the light receiving sensor, and the determination means 54 determines that the position of the bar magnet 22 is appropriate. (Step 6), the signal is given from the judging means 54 to the time measuring means 50, and the time counting operation of the timer 48 is started (Step 5-2). If it is determined in step 6 that the position of the bar magnet 22 is not appropriate, a signal is given from the determination means 54 to the display means 56 and an error is displayed on the display 18 (step 7). Similar to the example. In addition, after the time counting operation of the timer 48 is started in step 5-2, the operation waits for 10 seconds (step 8), and the operation is the same as that of the first embodiment.

Furthermore, a third embodiment of the blood coagulation time measuring apparatus of the present invention will be described with reference to FIGS. FIG. 12 is a flowchart of the third embodiment of the blood coagulation time measuring apparatus of the present invention. FIG. 13 is a time chart of the third embodiment. 12 and 13, members and operations that are the same as or equivalent to those shown in FIGS. 1 to 11 are assigned the same reference numerals, and redundant descriptions are omitted.

In the first embodiment, the position setting magnet 38 is disposed near the opening of the insertion hole 24 a of the measurement unit 24, so that the position of the bar magnet 22 of the measurement cartridge 14 inserted into the measurement apparatus main body 10. However, it is made to be on the flat portion 14b side of the measurement cartridge 14. As a result, the measurement blood 42 flows only to the narrowed portion 14d on the flat portion 14b side of the thin tube portion 14c, the amount of the measurement blood 42 is small, and the rod-shaped magnet 22 is located on the distal end side of the distal end small diameter portion 14a in the narrow tube portion 14c. Even if moved, the measurement blood 42 does not overflow from the measurement blood inlet 20. In the third embodiment, the position of the bar-shaped magnet 22 of the measuring cartridge 14 inserted into the measuring apparatus main body 10 is on the narrowed portion 14c side by the electromagnetic coil 28 that reciprocates the bar-shaped magnet 22. To do. Therefore, the position setting magnet 38 becomes unnecessary. In the third embodiment, as shown in the flowchart of FIG. 12, when the temperature sensor 36 detects that the temperature of the measuring unit 24 has increased to 37 ° C. (step 2), the detection signal is sent to the microcomputer. 44, the display 18 displays “ready OK”, and the electromagnetic coil current control means 46 provides a negative current so that the bar magnet 22 is on the flat portion 14b side of the electromagnetic coil 28. Is energized (step 3-1). The negative pole energization of the electromagnetic coil 28 is shown in FIG. Therefore, when the measurement cartridge 14 is inserted, the bar magnet 22 is positioned on the flat portion 14b side as shown in FIG. Therefore, the structure can be simplified and the manufacturing cost can be reduced to the extent that the position setting magnet 38 as in the first embodiment is not required.

  Further, a fourth embodiment of the blood coagulation time measuring apparatus according to the present invention will be described with reference to FIGS. FIG. 14 is a partially cutaway cross-sectional view of the measurement unit of the fourth embodiment of the blood coagulation time measuring apparatus of the present invention, (a) is a partially cutaway cross-sectional view, and (b) is a partially cutaway view. It is a notch longitudinal cross-sectional view. FIG. 15 is a functional block diagram of the fourth embodiment. FIG. 16 is a flowchart of the fourth embodiment. 14 to 16, the same or equivalent members as those shown in FIGS. 1 to 13 are denoted by the same reference numerals, and redundant description is omitted.

As shown in FIG. 14, in the measurement cartridge 60 of the fourth embodiment, a rod-shaped steel body 62 made of a ferromagnetic material or the like is reciprocally movable within a predetermined range in the narrow tube portion 14c of the tip small diameter portion 14a. It is arranged. Note that a steel ball may be used instead of the rod-shaped steel body 62, and any ferromagnetic material may be used. In the measurement unit 64 of the fourth embodiment, the first electromagnetic coil 66 faces both ends of the reciprocating range of the rod-shaped steel body 62 in a state where the measurement cartridge 60 is completely inserted to a predetermined position. And a second electromagnetic coil 68 are respectively disposed. Therefore, as shown in FIG. 15, the microcomputer 44 is provided with electromagnetic coil current control means 46 for alternately energizing the first electromagnetic coil 66 and the second electromagnetic coil 68 every 10 seconds. The rod-shaped steel body 62 can be reciprocated in the same manner as in the first embodiment by attracting the rod-shaped steel body 62 with a magnetic force with the electromagnetic coil. The first electromagnetic coil 66, the second electromagnetic coil 68, and the electromagnetic coil current control means 46 constitute a steel body reciprocating means. As shown in FIG. 16, in the operation of the fourth embodiment, when 37 ° C. is detected by the temperature sensor 36 (step 2), “preparation OK” is displayed and the first electromagnetic coil 66 on the flat portion 14b side is applied. Energization is performed (step 3-2). Therefore, when the measurement cartridge 60 is inserted, the rod-shaped steel body 62 is attracted by energizing the first electromagnetic coil 66, and the rod-shaped steel body 62 can be positioned on the narrowed portion 14c side. . When the limit switch 26 is turned on (step 4), the second electromagnetic coil 68 is energized and the disclosure operation of the timer 48 is started (step 5-3). Here, if the rod-shaped steel body 62 is detected (step 6-1), after waiting for 10 seconds (step 8), the first electromagnetic coil 66 is energized again (step 9-1). Is detected. If not detected (step 10-1), the second electromagnetic coil 68 is energized (step 12-1) after waiting for 10 seconds again (step 11), and the rod-shaped steel body 62 is detected. When the rod-shaped steel body 62 is detected (step 13-1), the process returns to step 8. When the rod-shaped steel body 62 is detected in step 10-1, or when the rod-shaped steel body 62 is not detected in step 13-1, the process proceeds to step 14. In the fourth embodiment having such a structure, it is possible to provide the measurement cartridge 60 at a lower cost by using an inexpensive rod-shaped steel body 62 as a part of the measurement cartridge 60. In the fourth embodiment, the light source 30, the light receiving sensor 32, and the light receiving detecting means 52 constitute a steel body position detecting means.

  Furthermore, a fifth embodiment of the blood coagulation time measuring apparatus of the present invention will be described with reference to FIG. FIG. 17 is a functional block diagram of the fifth embodiment of the blood coagulation time measuring apparatus of the present invention. In FIG. 17, the same or equivalent members as those shown in FIGS. 1 to 16 are denoted by the same reference numerals, and redundant description is omitted.

In the fifth embodiment shown in FIG. 17, the structures of the measurement cartridge 60 and the measurement unit 64 are the same as those of the fourth embodiment. In the fifth embodiment, as shown in FIG. 17, the first electromagnetic coil 66 and the second electromagnetic coil 68 are alternately energized at predetermined time intervals by the electromagnetic coil current control means 46 when the limit switch 26 is turned on. Is started. With the start of the alternating energization, the rod-shaped steel body 62 is first moved from the flat portion 14b side to the tip side, the light receiving sensor 32 is shielded from light, and the rod-shaped steel body 62 is detected. The rod-shaped steel body 62 is moved to the side of the electromagnetic coil energized by the electromagnetic coil current control means 46, the position thereof is detected by the light receiving sensor 32, and the discriminating means 54 corresponds appropriately with the movement of the rod-shaped steel body 62. Assuming that it is in the position, a signal is given to the time measuring means 50 to start the time counting operation of the timer 48. The fifth embodiment is different from the fourth embodiment in that a signal for starting the time counting operation of the timer 48 is given from the determination means 54.

  In the first to third embodiments, the rod-shaped magnet 22 is positioned on the flat portion 14b side by energizing the negative pole to the electromagnetic coil 28, and the rod-shaped magnet 22 is turned to the small diameter end portion 14a by energizing the plus pole. However, if the polarity of both ends of the rod-shaped magnet 22 is reversed, the rod-shaped magnet 22 is positioned on the flat portion 14b side by energizing the electromagnetic coil 28 with the + -pole. It will be easily understood that the rod-shaped magnet 22 is positioned on the distal end small diameter portion 14a side by energization.

BRIEF DESCRIPTION OF THE DRAWINGS It is an external appearance perspective view of 1st Example of the blood coagulation time measuring apparatus of this invention, (a) shows the state before inserting the cartridge for measurement into a measuring apparatus main body, (b) is for measuring to a measuring apparatus main body. A state in which about half of the cartridge is inserted is shown, and (c) a state in which the measuring cartridge is completely inserted into the main body of the measuring apparatus is shown. It is a structural view of a cartridge for measurement, (a) is a top view, (b) is a left side view, (c) is a front view, (d) is an AA section arrow of (a). FIG. It is a structure figure of the measurement part built in a measuring device main part, (a) is a top view, (b) is a right view, (c) is a BB section arrow view of (a). (D) is a CC cross-sectional arrow view of (b). It is a notch top view which inserted the cartridge for measurement in the measurement part of the measuring device main part, (a) is a figure of the state which inserted the cartridge for measurement about half, (b) is the state which inserted the cartridge for measurement completely It is a figure of a state. It is a figure which shows the state which introduce | transduces measurement blood to the cartridge for a measurement, (a) shows the state before supplying measurement blood, (b) shows the state into which measurement blood was injected. It is a functional block diagram of a 1st example. It is a flowchart of 1st Example. It is a time chart in case blood coagulation time is 40 seconds as an example. It is a time chart in case blood coagulation time is 50 seconds as another example. It is a functional block diagram of 2nd Example of the blood coagulation time measuring apparatus of this invention. It is a flowchart of 2nd Example. It is a flowchart of 3rd Example of the blood coagulation time measuring apparatus of this invention. 13 is a time chart when the blood coagulation time is 40 seconds as an example in the flowchart of FIG. 12. It is a partially notched cross-sectional view of the measurement part of the fourth embodiment of the blood coagulation time measuring apparatus of the present invention, (a) is a partially notched cross-sectional view, (b) is a partially notched vertical cross-section FIG. It is a functional block diagram of 4th Example. It is a flowchart of 4th Example. It is a functional block diagram of 5th Example of the blood coagulation time measuring apparatus of this invention.

DESCRIPTION OF SYMBOLS 10 Measuring apparatus main body 12 Cartridge insertion hole 14, 60 Measuring cartridge 14a Tip thin diameter part 14b Flat part 14c Narrow tube part 14d Narrow part 14e Peripheral wall 14f Spherical recessed part 14g Concave groove 16 Power switch 18 Display 20 Measurement blood inlet 22 Rod shape Magnets 24, 64 Measuring unit 24a Insertion hole 26 Limit switch 28 Electromagnetic coil 30 Light source 32 Light receiving sensor 34 Heater 36 Temperature sensor 38 Position setting magnet 40 Plunger 42 Measuring blood 44 Microcomputer 46 Electromagnetic coil current control means 48 Timer 50 Time measuring means 52 Light reception detection means 54 Discrimination means 56 Display means 58 Temperature controller 62 Rod-shaped steel body 66 First electromagnetic coil 68 Second electromagnetic coil

Claims (11)

A measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole. A narrow tube portion that extends in the lateral direction of the insertion direction in communication with the input port is provided, and a narrowed portion is provided in the middle and at the tip of the narrow tube portion, and both ends are formed between the two narrowed portions in the narrow tube portion. A pole-shaped magnet and a pole-shaped magnet are arranged so as to be reciprocally movable in a predetermined range in the insertion direction. When the rod-shaped magnet is on the narrowed portion on the way, the narrowed portion is closed. , a means for the rod-shaped magnet for closing the constriction as in constriction side of the middle suction by a magnetic force when said measurement cartridge is inserted into the cartridge insertion hole provided, the A magnet reciprocating means for causing said rod-shaped magnet of the measuring cartridge which is inserted into cartridges insertion hole reciprocates in the insertion direction by suction by a magnetic force to switch at a predetermined time interval is provided, the light is blocked by the opaque the bar magnet the magnet position detecting means for detecting a state where the rod-shaped magnet is biasing the one end of the reciprocating Te provided, wherein there should position of said rod-shaped magnet is moved is sucked by the magnetic force of the magnet reciprocating means A discriminating means for discriminating whether or not the position of the bar magnet actually detected by the magnet position detecting means coincides is provided, and the discriminating means starts the reciprocating movement of the bar magnet by the magnet reciprocating means. time measuring means for measuring the time until determining that the position of the rod-shaped magnet does not match provided, the measured blood time measured by said time measuring means Blood coagulation time measuring apparatus, characterized in that which is configured by providing a display means for displaying a blood coagulation time. A measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole. A narrow tube portion that extends in the lateral direction of the insertion direction in communication with the input port is provided, and a narrowed portion is provided in the middle and at the tip of the narrow tube portion, and both ends are formed between the two narrowed portions in the narrow tube portion. A pole-shaped magnet and a pole-shaped magnet are arranged so as to be reciprocally movable in a predetermined range in the insertion direction . When the rod-shaped magnet is on the narrowed portion on the way, the narrowed portion is closed. , a means for the rod-shaped magnet for closing the constriction as in constriction side of the middle suction by a magnetic force when said measurement cartridge is inserted into the cartridge insertion hole provided, the A magnet reciprocating means for causing said rod-shaped magnet of the measuring cartridge which is inserted into cartridges insertion hole reciprocates in the insertion direction by suction by a magnetic force to switch at a predetermined time interval is provided, the light is blocked by the opaque the bar magnet the magnet position detecting means for detecting a state where the rod-shaped magnet is biasing the one end of the reciprocating Te provided, wherein there should position of said rod-shaped magnet is moved is sucked by the magnetic force of the magnet reciprocating means A discriminating unit for discriminating whether or not the positions of the bar magnets actually detected by the magnet position detecting unit coincide with each other, and the reciprocating movement of the bar magnet by the magnet reciprocating unit is started. to measure the time until it is determined that the position of the bar magnet by the determination means since it is discriminated that the position of the bar magnet is matched does not correspond The provided time measuring means, said measured by time measuring means blood coagulation time measuring apparatus, characterized in that which is configured by providing a display means for displaying the time as a blood coagulation time of the measurement blood. In the blood coagulation time measuring apparatus according to claim 1 or 2, provided an insertion detecting means for the measuring cartridge to detect this is pressed when to be inserted to a predetermined position of the cartridge insertion hole, wherein in the insertion detecting means A blood coagulation time measuring apparatus configured to start reciprocating movement of the bar magnet by the magnet reciprocating means when insertion of a measuring cartridge is detected. 3. The blood coagulation time measuring apparatus according to claim 1 or 2, wherein the time measuring means includes a timer, with the start of reciprocation of the bar magnet by the magnet reciprocating means, or by the discriminating means. It is determined that the position corresponds, the timer starts the timing operation, and when the determination means determines that the position of the bar magnet does not correspond, the timing operation is stopped. A blood coagulation time measuring device characterized by the above. 3. The blood coagulation time measuring device according to claim 1 or 2, wherein the magnet reciprocating means includes an electromagnetic coil in which the measuring cartridge inserted into the cartridge insertion hole is loosely fitted, and a direction of a current flowing through the electromagnetic coil. A blood coagulation time measuring device comprising an electromagnetic coil current control means for switching at a predetermined time interval. 3. The blood coagulation time measuring apparatus according to claim 1 or 2, wherein at least a portion of the measuring cartridge for detecting a state in which the bar magnet is biased toward one end of the reciprocating movement is formed transparent, and the bar magnet is opaque. The light source, the light receiving sensor, and the light receiving member that are disposed between and sandwich the magnet position detecting means facing the portion that detects the state where the opaque bar-shaped magnet is biased toward one end side where the reciprocating movement is performed. A blood coagulation time measuring device comprising: a light receiving detection means to which a signal from a sensor is given. 3. The blood coagulation time measuring apparatus according to claim 1, wherein a position setting magnet for attracting the bar magnet is provided near the opening of the cartridge insertion hole, and the measurement cartridge is inserted into the cartridge insertion hole. In addition, the blood coagulation time measurement is characterized in that the rod-shaped magnet is attracted by the magnetic force of the position setting magnet so that the rod-shaped magnet is located on the middle narrowed portion side in the narrow tube portion and closes the narrowed portion. apparatus. 8. The blood coagulation time measuring device according to claim 7, wherein the first click means for holding the state where the measurement cartridge is inserted to a predetermined position of the cartridge insertion hole, and the measurement cartridge is about half of the cartridge insertion hole. A second click means for holding the inserted state is provided, and the rod-shaped magnet is attracted by the magnetic force of the position setting magnet while being held by the second click means, so that the rod-shaped magnet is in the narrow tube portion side in the middle of the narrowed portion The blood clotting time measurement is characterized in that the stenosis portion is closed at the position and the measurement blood can be introduced into the measurement blood inlet while being held by the second click means. apparatus. In the blood coagulation time measuring apparatus according to claim 5, wherein the cartridge when the measurement cartridge in the insertion hole is inserted, wherein an electromagnetic coil current control means, before Symbol constriction of the middle rod-shaped magnet in the narrow tube portion A blood coagulation time measuring device, characterized in that a current is passed through the electromagnetic coil so as to close the stenosis portion . A measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole. An inlet and a narrow tube portion communicating therewith and extending in the lateral direction of the insertion direction are provided , a narrowed portion is provided in the middle and the tip of the narrow tube portion, and a steel ball or a rod-like shape is provided between the two narrowed portions in the narrow tube portion The steel body is disposed so as to be reciprocally movable in a predetermined range in the insertion direction, and when the steel body is on the middle narrow portion, the narrow portion is closed . cartridge provided with means wherein the steel body for closing the constriction as in constriction side of the middle suction by a magnetic force when being inserted into the cartridge insertion port, the cartridge insertion Each disposed first electromagnetic coil and a second electromagnetic coil on the opposite ends of the reciprocating movement of the inserted the steel body of the measuring cartridge, the first electromagnetic coil and a predetermined time to the second electromagnetic coil A steel body reciprocating means for reciprocally moving the steel body in the insertion direction at a predetermined time interval by flowing a current alternately at intervals and attracting by magnetic force is provided, and the opaque steel body blocks light and the steel body Is provided with a steel body position detecting means for detecting a state where the steel body is biased toward one end of the reciprocating movement, and the steel body to be moved by being attracted by the magnetic force of the steel body reciprocating means and the steel body discrimination means for actually detected position of the steel body at a position detecting means for determining whether the match provided, wherein by said discriminating means from the start of the reciprocating movement of the steel member by the steel body reciprocating means this position of the steel body do not match Blood coagulation time, characterized in that it is provided with a time measurement means for measuring the time until it is determined, and a display means for displaying the time measured by the time measurement means as the blood coagulation time of the measured blood measuring device. A measuring device main body having a cartridge insertion hole provided in a lateral direction and a measurement cartridge that can be inserted into the cartridge insertion hole. An inlet and a narrow tube portion communicating therewith and extending in the lateral direction of the insertion direction are provided , a narrowed portion is provided in the middle and the tip of the narrow tube portion, and a steel ball or a rod-like shape is provided between the two narrowed portions in the narrow tube portion The steel body is disposed so as to be reciprocally movable in a predetermined range in the insertion direction, and when the steel body is on the middle narrow portion, the narrow portion is closed . cartridge provided with means for closing the constriction the steel body as in constriction side of the middle suction by a magnetic force when being inserted into the cartridge insertion hole, the cartridge insertion Each disposed first electromagnetic coil and a second electromagnetic coil on the opposite ends of the reciprocating movement of the inserted the steel body of the measuring cartridge, the first electromagnetic coil and a predetermined time to the second electromagnetic coil the steel body reciprocating means for reciprocating the steel body by suction by the magnetic force by applying a current alternately the insertion direction at a predetermined time interval is provided at intervals, the steel body light is blocked by the opaque the steel body Is provided with a steel body position detecting means for detecting a state where the steel body is biased toward one end of the reciprocating movement, and the steel body to be moved by being attracted by the magnetic force of the steel body reciprocating means and the steel body A discriminating means for discriminating whether or not the positions of the steel bodies actually detected by the position detecting means coincide with each other , and the reciprocating movement of the steel bodies by the steel body reciprocating means is started. that the position of the steel body is matched Time measuring means for measuring the time until determining that the position of the steel member by said discrimination means from being another do not match provided, the measured time by the time measuring means said measured blood Blood A blood coagulation time measuring apparatus comprising a display means for displaying as a coagulation time.