JP5373497B2 - Measuring device with temperature chamber control function - Google Patents

Description

  The present invention relates to a measuring apparatus including a thermostatic chamber control function. Specifically, the present invention relates to improvement in operability of the measurement apparatus, and automation and multifunctionalization of the measurement apparatus.

Various substances such as chemicals and solutions thereof have the property of rotating the polarization plane of linearly polarized light to the right or left, that is, the optical rotation. Optical rotation is said to be related to the chemical structure of the substance. By measuring the optical rotation, which is a measure of optical rotation, specifically the angle at which the substance rotates the plane of polarization, it is possible to identify the substance or identify the optical isomer.
Since the optical rotation varies depending on the temperature of the substance, when measuring the optical rotation using an optical rotation measuring device, it is important to manage the temperature of the substance that is the sample. For example, the pharmacy method stipulates that the temperature management of the sample is strictly performed, and the conventional optical rotation measuring device is provided with a sample temperature control means for controlling the temperature of the sample to the specified temperature. If a specified temperature is input as the set temperature of the sample temperature control means, the optical rotation of the sample at the specified temperature can be measured.

  As a sample temperature control means, one using a heating / cooling effect by a Peltier effect of a Peltier element has been conventionally known (for example, Patent Document 1). A sample in a liquid state is usually measured by being placed in a flow cell attached to a measuring apparatus, and the temperature is controlled by covering the flow cell with a Peltier element. The cell holder that holds the flow cell so as to be covered with the Peltier element is called a Peltier constant temperature cell holder, and is suitable for controlling the temperature of the sample with high accuracy in measurement near or below room temperature. For example, when the room temperature is 20 ° C., there is a Peltier constant temperature cell holder in which the temperature control range of the sample by the Peltier element is 15 to 40 ° C., and a temperature control accuracy of ± 0.2 ° C. is obtained.

  The Peltier element has the effect of transferring heat from one surface to the other when a current flows. Further, the direction of heat transfer can be switched by changing the direction in which the current flows. Therefore, if the back surface temperature is maintained at a predetermined reference temperature, the surface temperature can be accurately adjusted by current control. In order to improve the temperature control accuracy, the water jacket structure that covers the Peltier element is used to exchange heat between the temperature-controlled circulating water and the Peltier element to maintain the back surface temperature of the element at the reference temperature. Peltier thermostat cell holders of the type have been used. Circulating water into the water jacket is supplied from an external thermostat.

JP 2008-203170 A

However, when measuring physical properties of a sample at a set temperature using a water jacket-structured cell and a thermostatic chamber that supplies circulating water, as in the above-described optical rotation measurement device, in the conventional measurement device, There was a problem.
The constant temperature bath used in the conventional measuring device has a function of supplying circulating water at a constant temperature, and although the temperature and flow rate of circulating water can be set manually, the temperature and flow rate are set by receiving a signal from an external computer. It does not have a function to change automatically, but only works independently. On the other hand, a conventional cell holder can detect the temperature of a sample by a built-in temperature sensor and display the detected temperature of the sample on a measuring apparatus main body or a computer to which the cell holder is attached. The temperature and flow rate of the circulating water could not be automatically controlled according to the set temperature.
Therefore, the user has to keep an eye on the display value such as the detected temperature of the sample during the measurement, and manually change the setting of the temperature and flow rate of the circulating water as necessary. In addition, the fact that the thermostat does not have a function of exchanging signals with external devices has been a cause of hindering measurement automation and multifunctionalization.
Accordingly, an object of the present invention is to provide a measuring device that has a user-friendly operability and includes a thermostatic bath control function that facilitates automation and multi-function of measurement.

In order to solve the above-described problems, a measuring apparatus including a thermostatic chamber control function according to the present invention includes a measuring apparatus main body having the following configuration. That is, the main body of the measuring apparatus adjusts the reference cell to the sample cell, the Peltier element that covers the sample cell, heats or cools the sample by the Peltier effect, and the back surface of the Peltier element opposite to the sample cell. Therefore, a water jacket for performing heat exchange between the Peltier element and the circulating water is provided. The measurement apparatus main body controls the differential temperature between the reference temperature and the sample temperature by the Peltier element, thereby adjusting the sample to a predetermined set temperature and measuring the physical properties of the sample at the adjusted set temperature. Further, the measurement device includes a thermostatic bath provided separately from the measurement device main body. The thermostat adjusts the temperature or flow rate of the circulating water, supplies the circulating water to the water jacket, and receives the circulating water from the water jacket. Moreover, the measuring apparatus has a program for controlling the thermostatic bath and includes a computer that executes the program.
The measurement apparatus main body and the computer are connected by a first signal line, and exchange information on the set temperature of the sample. The computer calculates the necessary reference temperature based on the information on the temperature control range of the Peltier element and the information on the set temperature of the received sample. The thermostatic chamber and the computer are connected by a second signal line, and exchange control signals including a set temperature or set flow rate of circulating water for obtaining the reference temperature.

According to the present invention, for example, in a circulating water type Peltier thermostat cell holder, the control of the thermostatic chamber necessary for adjusting the sample to the set temperature is performed by a computer according to the temperature control range of the Peltier element, without manual operation. Can be controlled automatically. That is, the computer calculates the required reference temperature on the back of the Peltier element based on the information on the temperature control range of the Peltier element and the set temperature information of the sample, and uses the set temperature or set flow rate of the thermostat according to this reference temperature. The thermostat can be controlled.
For example, if the set temperature of the sample is changed within the temperature control range of the Peltier element, it can be adjusted to the set temperature simply by controlling the current value to the Peltier element without changing the reference temperature. However, if it is desired to change the set temperature of the sample beyond the temperature control range of the Peltier element, it is necessary to change the reference temperature on the back of the element, and the temperature or flow rate of the circulating water must be adjusted. According to the present invention, since the temperature or flow rate of circulating water in the thermostat can be controlled by a computer, the set temperature of the sample can be easily exceeded beyond the temperature control range of the Peltier element without using manual operation as in the past. Can be changed.

Further, the sample contained a control function of a thermostat according to the present invention measuring device may further include that the first temperature detecting section for detecting a temperature of the sample in the sample cell, consisting of a sample of the same material in the sample cell The sample container part for adjusting the concentration and the circulating water from the water jacket are received, and heat exchange is performed between the received circulating water and the sample in the sample container. A sample heat retaining water tank that discharges the circulating water toward the thermostat and a second temperature detection unit that detects the temperature of the sample in the sample container.
The first signal line further transmits and receives information on the detected temperature of the sample. It said second signal line is further exchanges the second detection of the temperature information from the temperature detecting unit is sent to the constant temperature bath. The computer calculates a set temperature or set flow rate of circulating water necessary to match the detected temperature of the sample in the sample container and the detected temperature of the sample in the sample cell, and uses the second signal line. It is preferable to transmit a control signal including the set temperature or set flow rate of the circulating water to the thermostatic bath.

According to the present invention, for example, in a circulating water type cell holder, the computer controls the temperature or flow rate of the constant temperature bath based on the detected temperature information of the sample in the sample cell and the detected temperature information of the sample in the sample container. Thus , the temperature of the sample in the sample cell and the temperature of the sample in the sample container can be automatically matched. At the same time, the sample in the sample cell can be adjusted to the set temperature by controlling the thermostatic chamber based on the reference temperature on the back of the Peltier element calculated by the computer.

  According to the measuring device including the thermostatic chamber control function of the present invention, it is possible to provide a measuring device including a thermostatic chamber control function that is excellent in user operability and facilitates automation and multi-function of measurement. Can do.

It is a block diagram which shows schematic structure of the optical rotation measuring device containing the control function of the thermostat which concerns on 1st embodiment of this invention. It is a block diagram which shows schematic structure of the optical rotation measuring apparatus containing the control function of the thermostat which concerns on 2nd embodiment of this invention. It is a perspective view which shows the external appearance of the thermostat in each embodiment of this invention. It is a left side view which shows the internal structure of the said thermostat. It is a front view which shows the internal structure of the said thermostat. It is a right side view which shows the internal structure of the said thermostat.

Embodiments of an optical rotation measuring apparatus according to the present invention will be described below with reference to the drawings.
<First embodiment>
As shown in FIG. 1, the optical rotation measuring device 10 includes a measuring device main body 1 containing a cell holder 11, a thermostat 2 for supplying circulating water to the cell holder 11, a signal to the measuring device main body 1 and the thermostatic bath 2. Is a device that measures the optical rotation of the sample while circulating the circulating water through the cell holder 11.
The cell holder 11 is detachably attached to the measuring apparatus main body 1. When the cell holder 11 and the measuring device main body 1 are connected to each other by an internal pipe for circulating water while being attached to the measuring device main body 1, the circulating water supplied from the external thermostat 2 to the measuring device main body 1. Is supplied to the cell holder 11 via an internal pipe.

The cell holder 11 includes a cell part 12 into which a sample is introduced, a Peltier element 13 provided in contact with the cell part 12, and a water jacket provided so as to cover the cell part 12 with the Peltier element 13 interposed therebetween. 14, a sample temperature sensor 15 that directly detects the temperature of the sample, and a sample temperature control unit 16, and is called a circulating water type Peltier constant temperature cell holder (hereinafter referred to as cell holder 11).
The cell unit 12 corresponds to a sample cell into which the sample of the present invention is placed. When the measurement is finished, the sample in the cell is discharged and the next sample is sent in. The sample temperature sensor 15 corresponds to a first temperature detection unit of the present invention.

A predetermined current controlled by the sample temperature control unit 16 is applied to the Peltier element 13. When the direction of the current flowing through the Peltier element 13 is changed, heat generation (heating) and heat absorption (cooling) due to the Peltier effect are switched.
The sample temperature control unit 16 determines the current value to the Peltier element 13 based on the detected temperature from the sample temperature sensor 15 and the set temperature of the sample in the cell holder 11 so that the difference between the two temperatures becomes small. That is, the direction of the current and the current value are appropriately changed so that the detected temperature of the sample in the cell unit 12 approaches the set temperature.
The sample temperature control unit 16 exchanges signals with an external computer 3 through a first USB cable 4 which is a first signal line to be described later, and detects the detected temperature of the sample and the Peltier element 13 to the computer 3. Outputs information on temperature control range and set temperature. Information about the temperature control range of the Peltier element 13 or the set temperature of the sample may be stored in the computer 3 in advance.

The Peltier element 13 has a front surface and a back surface, and is arranged so that the front surface faces the cell portion 12 and the back surface faces the water jacket 14 on the opposite side to the cell portion 12.
The water jacket 14 is for performing heat exchange between the sample and the circulating water in order to control the temperature of the sample to the set temperature with high accuracy. The circulating water indirectly exchanges heat with the sample via the Peltier element 13. Specifically, the back surface of the Peltier element 13 is cooled or heated by the circulating water flowing through the water jacket 14, and the back surface temperature of the Peltier element 13 is adjusted to a predetermined reference temperature. Since the range of temperature adjustment by the Peltier element 13 is determined by the temperature difference between the front surface and the back surface, the sample temperature can be controlled with high accuracy by keeping the reference temperature on the back surface of the element constant. In this way, the water jacket 14 performs heat exchange between the Peltier element 13 and the circulating water in order to adjust the back surface of the Peltier element 13 to the reference temperature. Then, the Peltier element 13 controls the differential temperature between the adjusted reference temperature and the sample temperature to adjust the sample to a predetermined set temperature.
With the above configuration, the cell holder 11 controls the temperature of the sample with the built-in Peltier element 13 and the circulating water in the water jacket 14.

  The thermostat 2 is provided separately from the measuring device main body 1 and supplies the circulating water adjusted to a constant temperature or a set temperature to the measuring device main body 1. The supplied circulating water is further fed into the water jacket 14 to exchange heat with the sample. The circulating water discharged from the water jacket 14 returns to the thermostat 2 and the temperature is adjusted again in the thermostat. Thus, the thermostatic chamber supplies and receives the circulating water, and adjusts the flow rate of the circulating water in addition to adjusting the temperature of the circulating water.

A specific configuration of the thermostat 2 will be described. The constant temperature bath 2 is provided in an axial flow pump 21 that also serves as a circulating water supply unit and a flow rate adjustment unit, an electric motor 22 that is a power source of the axial flow pump 21, a water tank unit 23 that stores the circulating water, and a water tank unit 23. The Peltier element 24, which is a temperature adjusting unit, a temperature / flow rate control unit 25 of circulating water, an operation panel 26, and a USB terminal unit 27 for exchanging signals with the computer 3 are configured.
The axial flow pump 21 is housed in the water tank 23 and rotates the screw to pump the circulating water to the measuring device main body 1. The electric motor 22 is provided outside the water tank unit 23, is magnetically connected to the axial flow pump 21, and rotates the screw in a non-contact manner. Since the axial flow pump 21 and the electric motor 22 are magnetically coupled, the water tank 23 can be completely sealed, and there is an effect of preventing water leakage at the time of falling.
Moreover, the axial flow pump 21 rotates a screw by the set rotation speed. The temperature / flow rate control unit 25 adjusts the flow rate of the circulating water by changing the rotational speed of the axial flow pump 21.

The water tank unit 23 stores the circulating water and receives the circulating water from the water jacket 14.
The Peltier element 24 is provided in the water tank part 23, directly contacts with the circulating water, and performs heat exchange with the circulating water by the Peltier effect. The temperature / flow rate control unit 25 controls the current applied to the Peltier element 24 to adjust the temperature of the circulating water.
The temperature / flow rate control unit 25 controls the Peltier element 24 based on the set temperature input by the operation panel 26 provided in the housing of the thermostat 2. Further, the axial flow pump 21 is controlled based on the set flow rate input through the operation panel 26. Further, the temperature / flow rate control unit 25 can also control the Peltier element 24 or the axial flow pump 21 based on a control signal from the computer 3.

The computer 3 calculates a necessary reference temperature based on, for example, information A on the temperature control range of the Peltier element 13 and information B on the set temperature of the sample. Furthermore, it has a program for calculating the set temperature or set flow rate of the circulating water according to the calculated reference temperature and transmitting the control signals C and E for changing the set temperature or set flow rate of the thermostat 2 to the thermostat 2. Alternatively, the computer 3 may have a program for controlling the temperature of the circulating water or the flow rate of the circulating water in the thermostat 2 so that the detected temperature of the sample becomes the set temperature of the sample.
As shown in FIG. 1, the measurement apparatus main body 1 and the computer 2 are connected by a first USB cable 4, and each of temperature control range information A, set temperature information B, and sample detection temperature information D relating to the cell holder 11. Send and receive information. The thermostat 2 and the computer 3 are connected by a second USB cable 5 as a second signal line, and exchange the control signal C for temperature adjustment or the control signal E for flow rate adjustment.
The computer 3 executes the program to calculate the control signal C for adjusting the temperature of the circulating water or the control signal E for adjusting the flow rate of the circulating water so that the detected temperature of the sample becomes the set temperature. The control signal C or E calculated by the USB cable 5 is transmitted to the thermostat 2.

If the optical rotation measuring device 10 of this embodiment is used, it becomes possible to widen the setting range of the set temperature of a sample by raising the temperature of circulating water. As an example, a case will be described in which the temperature control range of the Peltier element 13 (the maximum temperature difference between the front and back surfaces of the Peltier element) is 20 ° C., and the set temperature of the sample is changed from 25 ° C. to 55 ° C., which is 30 ° C. higher.
Even in the conventional optical rotation measuring device, in principle, the temperature of the sample can be made higher than the temperature control range of the Peltier element by increasing the temperature of the circulating water. However, in the conventional optical rotation measuring device, the temperature of the circulating water cannot be changed unless it is manually operated using an operation button of a thermostatic bath. That is, it is necessary to operate the thermostat alone, and the operation is very inconvenient.

  On the other hand, in the optical rotation measuring device 10 of this embodiment, the control function of the computer 3 with respect to the measuring device main body 1 and the thermostat 2 is used, and information on the temperature control range (here, maximum 20 ° C.) of the Peltier element 13 is used. The set temperature of the circulating water can be automatically changed according to the information B of A and the set temperature of the sample (here 55 ° C.). Specifically, the computer 3 obtains the temperature control range information A and the set temperature information B via the first USB cable 4, respectively, calculates a necessary reference temperature by executing a program, The set temperature of the circulating water according to the reference temperature is calculated, and the obtained set temperature is transmitted to the thermostat 2 as a control signal C for the thermostat 2. Alternatively, the computer 3 may calculate a set flow rate of necessary circulating water and transmit the control signal E of the thermostatic bath 2.

  As described above, according to the program of the computer 3, the set temperature of the circulating water in the thermostat 2 is automatically changed by interlocking all the devices of the measuring device body 1, the cell holder 11, and the thermostat 2, and the sample efficiently. The settable temperature range can be expanded. Therefore, the conventional inconvenience in operation is eliminated, and the convenience for the user is improved.

In addition, after the sample temperature control by the Peltier element 13 is started by the cell holder 11 using the optical rotation measuring device 10 of the present embodiment, the detected temperature of the sample does not reach the set temperature even after a certain time has passed. Can automatically change the set temperature of the thermostatic chamber 2 as follows, and can shorten the adjustment time of the sample temperature. That is, the computer 3 obtains the set temperature information B of the sample and the detected temperature information D of the sample by the sample temperature sensor 15 and calculates the necessary set temperature of circulating water by executing a program. The set temperature thus transmitted is transmitted as a control signal G to the thermostatic chamber 2. Therefore, when the user adjusts the temperature of the sample while paying attention to the temperature fluctuation of each device as in the past, and the sample does not reach the set temperature even after a certain period of time, the set temperature of the circulating water is manually operated. The convenience of the user is improved and the time for adjusting the sample temperature can be greatly shortened.
Further, by simultaneously adjusting the temperature of the circulating water by the Peltier element 24 in the thermostat 2 and the temperature of the sample by the Peltier element 13 in the cell holder 11, the time until the sample reaches the set temperature is shortened. It is also possible.

<Second embodiment>
As shown in FIG. 2, the optical rotation measuring device 10 </ b> A includes a configuration common to the above-described embodiment. Here, description of common configurations is omitted, and only different configurations are described. That is, in the optical rotation measuring apparatus 10A of the present embodiment, the circulating water discharged from the cell holder 11 passes through the sample heat retaining water tank 6 arranged separately from the measuring apparatus main body 1 and returns to the thermostatic tank 2. The point which is comprised differs greatly from the said embodiment.

The sample heat retaining water tank 6 includes a sample water tank section 62 having a capacity that allows the sample container section 61 to be immersed in the circulating water.
The sample container unit 61 contains a sample made of the same material as the sample of the cell unit 12, and is provided with a sample temperature sensor 28 that is a second temperature detection unit that directly detects the temperature of the sample.
The sample water tank unit 62 receives at least a part of the circulating water from the water jacket 14, performs heat exchange between the received circulating water and the sample in the sample container unit 61, and maintains the circulating water after heat exchange at a constant temperature. It discharges toward the tank 2A. As shown in FIG. 2, a bypass may be provided in which the circulating water from the cell holder 11 returns directly to the constant temperature bath 2 </ b> A without passing through the sample heat retaining water bath 6.

The thermostat 2 </ b> A is connected to the sample temperature sensor 28 via a third signal line 29, and acquires the detected temperature information F of the sample from the sample temperature sensor 28. Therefore, the thermostat 2A is provided with a terminal 30 for connecting the third signal line 29. The detected temperature information F of the sample is transmitted to the temperature / flow rate control unit 25 and is also transmitted to the computer 3 via the second USB cable 5.
The computer 3 calculates the necessary set flow rate of circulating water based on the sample detection temperature information F and the sample detection temperature information D so that the sample detection temperature matches the sample detection temperature. A program for transmitting the control signal H including the set flow rate to the thermostat 2A.

  Regulations such as the Japanese Pharmacy Law stipulate the temperature and concentration of the sample. Therefore, at the time of measurement, it is necessary to dissolve the sample and adjust its concentration. At the time of sample dissolution and concentration adjustment, in order to accurately adjust the concentration, it is necessary to match the sample temperature (hereinafter referred to as the sample adjustment temperature) with the measurement temperature of the sample. Here, the temperature detected by the sample temperature sensor 15 is used as the sample measurement temperature.

  If the optical rotation measuring device 10A of the present embodiment is used, the detected temperature information D of the sample is transmitted from the measuring device main body 1 to the computer 3, and the detected temperature information F of the sample passes through the thermostat 2A. And transmitted to the computer 3. Therefore, the computer 3 executes the program, compares the detected temperature information D of the sample and the detected temperature information F of the sample, and calculates the set flow rate of circulating water so that both temperatures coincide. Then, the calculated set flow rate is transmitted to the thermostat 2A via the second USB cable 5 as the control signal H of the thermostat.

  Since the constant temperature bath 2A is provided with an axial flow pump 21 that serves both as a circulating water supply unit and a flow rate adjustment unit, the temperature / flow rate control unit 25 that receives the control signal H from the computer 3 causes the axial flow to flow. The rotation speed of the pump 21 is changed. In the present embodiment, the temperature / flow rate control unit 25 changes the number of rotations of the screw that is rotated by the electric motor 22, and the flow rate per hour of circulating water is, for example, three patterns of 10L / H, 20L / H, and 50L / H. You can choose from. The selection is performed by a control signal H from the computer 3 or an input signal from the operation panel 26. Note that the flow rate control of the circulating water is not limited to the one selected from such intermittent set flow rates, but may be control that continuously changes a predetermined flow rate range.

  Normally, circulating water flows through pipes connecting between devices, so that a temperature difference is generated between the adjustment temperature of the sample and the measurement temperature at the time of optical rotation measurement due to pipe resistance and heat radiation from the pipe. Therefore, in this embodiment, by controlling the flow rate of the circulating water and reducing the influence on the sample adjustment temperature due to heat absorption / dissipation of the circulating water from the pipe, the adjustment temperature of the sample and the measurement temperature at the time of optical rotation measurement Can be more accurately matched.

  When the optical rotation measuring device 10A as described above is used, all the devices of the measuring device main body 1, the cell holder 11, the constant temperature bath 2A, and the sample heat retaining water bath 6 are interlocked according to the program of the computer 3 to adjust the sample. The temperature and the measurement temperature at the time of optical rotation measurement can be automatically matched. Therefore, it is not necessary for the user to adjust the temperature of the sample while paying attention to the temperature fluctuation of each device, the convenience for the user is improved, and the temperature adjustment time of the sample can be greatly shortened.

In addition, FIGS. 3-6 shows the external appearance and internal structure of the thermostat 2, 2A used for the optical rotation measuring device of said 1st embodiment or 2nd embodiment concretely.
As shown in FIG. 3, an operation panel 26 having temperature and flow rate setting buttons 26 </ b> A and 26 </ b> B is provided on the upper surface of the case 31 of the thermostatic bath.
Moreover, as shown in FIGS. 4-6, the water tank part 23 provided with the axial flow pump 21 inside is arrange | positioned in the approximate center position inside a housing | casing. The water tank 23 has a Peltier element 24, and a pump motor 22 is provided on the water tank 23. Near the back of the inside of the housing (left side in the figure), a current supply unit 32 (corresponding to the temperature / flow rate control unit 25) to the Peltier element 24, a USB terminal 27 for connecting a second USB cable, a sample A terminal 30 for connecting the temperature sensor for operation is provided. In addition, a pair of connectors 33 for connecting an external pipe for circulating water is provided on one side surface.

In addition, the measuring apparatus including the thermostat control function of the present invention is not limited to the above-described embodiment, and the configuration can be changed as appropriate. For example, in the embodiment, the case of the optical rotation measuring devices 10 and 10A has been described. However, the present invention is not limited to this, and can be suitably used in a measuring device that measures at least the physical properties of the sample in the sample cell.
Further, in the first embodiment, instead of the method by adjusting the temperature of the circulating water, a method by adjusting the flow rate of the circulating water may be used.In the second embodiment, instead of the method by adjusting the flow rate of the circulating water, You may use the method by temperature adjustment of circulating water. Further, not only one of the adjustment methods, but both adjustment methods may be used simultaneously.
In both embodiments, the case where the circulating water type Peltier constant temperature cell holder is used has been described. However, the circulating water type Peltier constant temperature cell holder is provided with a sample cell and a water jacket covering the sample cell without providing a Peltier element. A constant temperature cell holder may be used.
1 and 2 show the case where the computer 3 is provided separately from the measuring apparatus main body 1, the computer 3 may be an arithmetic device such as a CPU built in the measuring apparatus main body 1. .
In addition, you may make it control the thermostat of this invention based on the information from not only a measurement apparatus like the measurement apparatus main body 1 but the other measurement apparatus connected to the computer 3. FIG.

  The measurement device including the thermostatic chamber control function according to the present invention is suitable for a measurement device that measures the physical properties of a sample in a sample cell covered with a water jacket.

DESCRIPTION OF SYMBOLS 1 Measurement apparatus main body 2, 2A Thermostatic bath 3 Computer 4 1st USB cable which is a 1st signal line 5 2nd USB cable which is a 1st signal line 6 Sample heat retention water tank 10, 10A With the measurement apparatus of this invention A certain optical rotation measuring device 11 Cell holder 12 Cell portion 13 serving as a sample cell 13 Peltier element 14 Water jacket 15 Temperature sensor 28 for a sample serving as a first temperature detecting portion Temperature sensor 61 for a sample serving as a second temperature detecting portion 61 Sample container portion 62 Sample water tank

Claims (2)

A sample cell to hold the sample,
A Peltier element that covers the sample cell and heats or cools the sample by the Peltier effect;
A water jacket for performing heat exchange between the Peltier element and circulating water to adjust the back surface of the Peltier element opposite to the sample cell to a reference temperature;
And measuring the physical properties of the sample at the adjusted set temperature while adjusting the sample to a predetermined set temperature by controlling the difference temperature between the reference temperature and the sample temperature by the Peltier element, and ,
A thermostat that is provided separately from the measuring device main body, adjusts the temperature or flow rate of the circulating water, supplies the circulating water to the water jacket, and receives the circulating water from the water jacket;
A measurement apparatus comprising a program for controlling the thermostatic chamber, and a computer for executing the program;
The measuring device main body and the computer are connected by a first signal line, and exchange information on the set temperature of the sample.
The computer calculates the required reference temperature based on information on the temperature control range of the Peltier element and information on the set temperature of the transferred sample,
The thermostat and the computer are connected by a second signal line, and exchange a control signal including a set temperature or set flow rate of circulating water to obtain the reference temperature.
A measuring device including a thermostatic chamber control function. The measuring device according to claim 1, further comprising:
A first temperature detector for detecting the temperature of the sample in the sample cell,
A sample container for concentration adjustment to put a sample consisting of a sample of the same material in the sample cell,
Accepts at least a part of the circulating water from the water jacket, causes heat exchange between the received circulating water and the sample in the sample container, and discharges the circulating water after the heat exchange toward the thermostat. A sample water bath,
And a second temperature detector for detecting the temperature of the sample of the sample container,
The first signal line further exchanges information on the detected temperature of the sample,
The second signal line further exchanges information on the detected temperature sent from the second temperature detector to the thermostat,
The computer calculates a set temperature or set flow rate of circulating water necessary to match the detected temperature of the sample in the sample container and the detected temperature of the sample in the sample cell, and the second signal line is calculated. A measuring apparatus including a thermostatic chamber control function, characterized in that a control signal including a set temperature or set flow rate of circulating water is transmitted to the thermostatic chamber.