JP5296701B2 - 線維性疾患および線維増殖性疾患を処置および診断するための方法 - Google Patents

線維性疾患および線維増殖性疾患を処置および診断するための方法 Download PDF

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JP5296701B2
JP5296701B2 JP2009539524A JP2009539524A JP5296701B2 JP 5296701 B2 JP5296701 B2 JP 5296701B2 JP 2009539524 A JP2009539524 A JP 2009539524A JP 2009539524 A JP2009539524 A JP 2009539524A JP 5296701 B2 JP5296701 B2 JP 5296701B2
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circulating
disease
fibroblasts
fibrotic
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JP2010511389A (ja
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ボーナ・メーラッド
マリー・ディ・バーディック
デイビッド・エイ・ジスマン
マイケル・ピー・キーン
ジョン・エイ・ベルペリオ
ロバート・エム・ストリーター
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University of California
University of California Berkeley
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
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    • G01N2800/122Chronic or obstructive airway disorders, e.g. asthma COPD

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  • Ophthalmology & Optometry (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009539524A 2006-11-30 2007-11-30 線維性疾患および線維増殖性疾患を処置および診断するための方法 Active JP5296701B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87201906P 2006-11-30 2006-11-30
US60/872,019 2006-11-30
PCT/US2007/086167 WO2008067559A2 (en) 2006-11-30 2007-11-30 Methods for treating and diagnosing fibrotic and fibroproliferative diseases

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JP2010511389A JP2010511389A (ja) 2010-04-15
JP2010511389A5 JP2010511389A5 (enExample) 2011-01-20
JP5296701B2 true JP5296701B2 (ja) 2013-09-25

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US (2) US8114608B2 (enExample)
EP (1) EP2100140B1 (enExample)
JP (1) JP5296701B2 (enExample)
AU (1) AU2007325029B2 (enExample)
WO (1) WO2008067559A2 (enExample)

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WO2008009437A2 (en) 2006-07-18 2008-01-24 Noxxon Pharma Ag Sdf-i binding nucleic acids
KR101589442B1 (ko) * 2007-08-06 2016-02-01 녹손 파르마 아게 에스디에프-1 결합형 핵산 및 이의 용도
CA2745027A1 (en) * 2008-10-22 2010-04-29 Allocure, Inc. Methods of using sdf-1 (cxcl12) as a diagnostic and mesenchymal stem cell (multipotent stromal cell)-specific therapeutic biomarker for the treatment of kidney injury and other major organs
JP2012127879A (ja) * 2010-12-16 2012-07-05 Kanazawa Univ 腎症の進行度の判定方法並びに線維化抑制剤。
CN103376228B (zh) * 2012-04-27 2016-02-17 中国人民解放军军事医学科学院放射与辐射医学研究所 一种检测或辅助检测放射性肺纤维化的试剂盒
EP2972380A2 (en) * 2013-03-14 2016-01-20 Galapagos NV Molecular targets and compounds, and methods to identify the same, useful in the treatment of fibrosis
JP6601707B2 (ja) * 2015-02-15 2019-11-06 国立大学法人金沢大学 線維化判定方法
JP7126668B2 (ja) * 2017-08-09 2022-08-29 国立大学法人金沢大学 膠原病判定方法

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US6759036B1 (en) 1997-03-28 2004-07-06 The Picower Institute For Medical Research Fibrocyte-base vaccine formulations
US8293479B2 (en) 2002-05-02 2012-10-23 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Use of parathyroid hormone-related protein(PTHRP) in the diagnosis and treatment of chronic lung disease and other pathologies
JP4922560B2 (ja) * 2002-12-23 2012-04-25 ウイリアム、マーシュ、ライス、ユーニヴァーサティ 線維細胞への分化の検出方法、線維症を抑制する組成物および方法

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AU2007325029A1 (en) 2008-06-05
JP2010511389A (ja) 2010-04-15
WO2008067559A3 (en) 2008-07-17
US8216796B2 (en) 2012-07-10
WO2008067559A2 (en) 2008-06-05
EP2100140B1 (en) 2015-05-06
AU2007325029B2 (en) 2013-09-12
US8114608B2 (en) 2012-02-14
US20100074887A1 (en) 2010-03-25
US20120094305A1 (en) 2012-04-19
EP2100140A4 (en) 2010-07-21
EP2100140A2 (en) 2009-09-16

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