JP5296701B2 - 線維性疾患および線維増殖性疾患を処置および診断するための方法 - Google Patents

線維性疾患および線維増殖性疾患を処置および診断するための方法 Download PDF

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JP5296701B2
JP5296701B2 JP2009539524A JP2009539524A JP5296701B2 JP 5296701 B2 JP5296701 B2 JP 5296701B2 JP 2009539524 A JP2009539524 A JP 2009539524A JP 2009539524 A JP2009539524 A JP 2009539524A JP 5296701 B2 JP5296701 B2 JP 5296701B2
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circulating
disease
fibroblasts
fibrotic
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JP2010511389A (ja
JP2010511389A5 (enExample
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ボーナ・メーラッド
マリー・ディ・バーディック
デイビッド・エイ・ジスマン
マイケル・ピー・キーン
ジョン・エイ・ベルペリオ
ロバート・エム・ストリーター
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University of California
University of California, Los Angeles
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University of California, San Diego
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G01N2800/122—Chronic or obstructive airway disorders, e.g. asthma COPD

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  • Physics & Mathematics (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009539524A 2006-11-30 2007-11-30 線維性疾患および線維増殖性疾患を処置および診断するための方法 Expired - Fee Related JP5296701B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87201906P 2006-11-30 2006-11-30
US60/872,019 2006-11-30
PCT/US2007/086167 WO2008067559A2 (en) 2006-11-30 2007-11-30 Methods for treating and diagnosing fibrotic and fibroproliferative diseases

Publications (3)

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JP2010511389A JP2010511389A (ja) 2010-04-15
JP2010511389A5 JP2010511389A5 (enExample) 2011-01-20
JP5296701B2 true JP5296701B2 (ja) 2013-09-25

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JP2009539524A Expired - Fee Related JP5296701B2 (ja) 2006-11-30 2007-11-30 線維性疾患および線維増殖性疾患を処置および診断するための方法

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US (2) US8114608B2 (enExample)
EP (1) EP2100140B1 (enExample)
JP (1) JP5296701B2 (enExample)
AU (1) AU2007325029B2 (enExample)
WO (1) WO2008067559A2 (enExample)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
JP5380287B2 (ja) 2006-07-18 2014-01-08 ノクソン・ファルマ・アクチエンゲゼルシャフト Ｓｄｆ−１結合核酸
PT2190991T (pt) * 2007-08-06 2019-12-16 Noxxon Pharma Ag Ácidos nucleicos que se ligam a sdf 1 e a sua utilização
CA2745027A1 (en) * 2008-10-22 2010-04-29 Allocure, Inc. Methods of using sdf-1 (cxcl12) as a diagnostic and mesenchymal stem cell (multipotent stromal cell)-specific therapeutic biomarker for the treatment of kidney injury and other major organs
JP2012127879A (ja) * 2010-12-16 2012-07-05 Kanazawa Univ 腎症の進行度の判定方法並びに線維化抑制剤。
CN103376228B (zh) * 2012-04-27 2016-02-17 中国人民解放军军事医学科学院放射与辐射医学研究所 一种检测或辅助检测放射性肺纤维化的试剂盒
US9952202B2 (en) * 2013-03-14 2018-04-24 Galapagos Nv Methods of identifying compounds for the treatment of fibrosis by using S1PR5
JP6601707B2 (ja) * 2015-02-15 2019-11-06 国立大学法人金沢大学 線維化判定方法
JP7126668B2 (ja) * 2017-08-09 2022-08-29 国立大学法人金沢大学 膠原病判定方法

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* Cited by examiner, † Cited by third party
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US6759036B1 (en) * 1997-03-28 2004-07-06 The Picower Institute For Medical Research Fibrocyte-base vaccine formulations
US8293479B2 (en) * 2002-05-02 2012-10-23 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Use of parathyroid hormone-related protein(PTHRP) in the diagnosis and treatment of chronic lung disease and other pathologies
JP4922560B2 (ja) * 2002-12-23 2012-04-25 ウイリアム、マーシュ、ライス、ユーニヴァーサティ 線維細胞への分化の検出方法、線維症を抑制する組成物および方法

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WO2008067559A2 (en) 2008-06-05
AU2007325029A1 (en) 2008-06-05
US20120094305A1 (en) 2012-04-19
US8114608B2 (en) 2012-02-14
US20100074887A1 (en) 2010-03-25
JP2010511389A (ja) 2010-04-15
US8216796B2 (en) 2012-07-10
EP2100140A4 (en) 2010-07-21
AU2007325029B2 (en) 2013-09-12
EP2100140A2 (en) 2009-09-16
WO2008067559A3 (en) 2008-07-17
EP2100140B1 (en) 2015-05-06

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