JP5289961B2 - 物質混合物の分析 - Google Patents
物質混合物の分析 Download PDFInfo
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- JP5289961B2 JP5289961B2 JP2008535880A JP2008535880A JP5289961B2 JP 5289961 B2 JP5289961 B2 JP 5289961B2 JP 2008535880 A JP2008535880 A JP 2008535880A JP 2008535880 A JP2008535880 A JP 2008535880A JP 5289961 B2 JP5289961 B2 JP 5289961B2
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- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N30/12—Preparation by evaporation
- G01N2030/121—Preparation by evaporation cooling; cold traps
- G01N2030/123—Preparation by evaporation cooling; cold traps using more than one trap
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/621—Detectors specially adapted therefor signal-to-noise ratio
- G01N2030/623—Detectors specially adapted therefor signal-to-noise ratio by modulation of sample feed or detector response
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8658—Optimising operation parameters
Description
2.工程1から得られた個々の被分析物の相対濃度分布を計算し、個々の被分析物の濃度分布行列と濃度ベクトルを求める工程と、
3.連立一次方程式を解いて、個々の被分析物の濃度を求める工程。
2.公知の擬似乱数の数列でアダマール変換する工程。
Claims (19)
- 分離装置に分析対象の複数の物質混合物を供給する工程と、なお、前記分離装置にはクロマトグラフィーによる分離法が用いられ、
前記分析対象の複数の物質混合物の物質を、化学的及び/または物理的移動手段を有する前記分離装置にて相互に分離させる工程と、
前記分離させた物質を評価装置で検出する工程と、を含む、物質混合物の分析方法であって、
前記分析対象の複数の物質混合物それぞれを、2進数列でパルス化して前記分離装置に供給し、
前記2進数列は個々の物質混合物の識別子として用いられる、
ことを特徴とする物質混合物の分析方法。 - 前記分析対象の複数の物質混合物のパルスが、時間的及び空間的に相互に分離された形態で分離装置に供給されることを特徴とする請求項1に記載の分析方法。
- 前記2進数列が、2進乱数発生器により作成されることを特徴とする請求項1または2に記載の分析方法。
- 前記2進数列が、反復配列で分割され、2進乱数発生器により作成された数列から形成されることを特徴とする請求項1ないし3のいずれか1項に記載の分析方法。
- 前記2進数列が、2nのパターンを有し、該nは5≦n≦128であることを特徴とする請求項1ないし4のいずれか1項に記載の分析方法。
- 前記2進数列が、2nのパターンを有し、該nは7≦n≦14であることを特徴とする請求項1ないし4のいずれか1項に記載の分析方法。
- 変調間隔(Δt)が、0.25〜120秒であることを特徴とする請求項1ないし6のいずれか1項に記載の分析方法。
- 変調間隔(Δt)が、1〜20秒であることを特徴とする請求項1ないし6のいずれか1項に記載の分析方法。
- パルス幅が、0.001〜1秒であることを特徴とする請求項1ないし8のいずれか1項に記載の分析方法。
- パルス幅が、0.001〜0.01秒であることを特徴とする請求項1ないし8のいずれか1項に記載の分析方法。
- 前記物質の検出が、前記物質混合物の供給と同期させた形態で、前記評価装置により行われることを特徴とする請求項1ないし10のいずれか1項に記載の分析方法。
- 前記評価装置が、前記変調間隔(パルス間隔の幅Δt)または前記変調間隔(パルス間隔の幅Δt)の一部と一致した検出時間で動作することを特徴とする請求項7ないし11のいずれか1項に記載の分析方法。
- 前記評価装置で検出された物質が、分析対象である前記物質混合物のパルスの2進数列で数学的にデコンボリューションされることを特徴とする請求項11または12に記載の分析方法。
- 前記評価装置で検出された物質が、分析対象である前記物質混合物のパルスの2進数列で、2次元の数学的デコンボリューションにより、数学的にデコンボリューションされることを特徴とする請求項11または12に記載の分析方法。
- 前記デコンボリューションの工程が、
前記評価装置により検出された前記物質を、前記2進数列でアダマール変換させる工程と、
前記評価装置により検出された前記物質の濃度分布を、前記アダマール変換させた結果から決定する工程と、
前記評価装置により検出されたそれぞれの前記物質の濃度を、前記濃度分布、前記評価装置で検出されたそれぞれの前記物質の濃度及び前記評価装置で検出された前記物質から形成される連立一次方程式を前記評価装置により解いて決定する工程と、を含むことを特徴とする請求項13または14に記載の分析方法。 - 前記分離装置には、ガスクロマトグラフィーまたは超臨界流体クロマトグラフィーを用いることを特徴とする請求項1ないし14のいずれか1項に記載の分析方法。
- 前記評価装置が、少なくとも1つの検出器を備えていることを特徴とする請求項1ないし16のいずれか1項に記載の分析方法。
- 前記評価装置が、少なくとも1つの分光検出器及び/または分光測定器を備えていることを特徴とする請求項1ないし16のいずれか1項に記載の分析方法。
- 前記2進数列は、各供給工程において一意的である、請求項1ないし18に記載の分析方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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DE102005050114A DE102005050114A1 (de) | 2005-10-18 | 2005-10-18 | Analyse von Stoffgemischen |
DE102005050114.1 | 2005-10-18 | ||
PCT/DE2006/001834 WO2007045224A2 (de) | 2005-10-18 | 2006-10-17 | Analyse von stoffgemischen |
Publications (3)
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JP2009511924A JP2009511924A (ja) | 2009-03-19 |
JP2009511924A5 JP2009511924A5 (ja) | 2012-03-29 |
JP5289961B2 true JP5289961B2 (ja) | 2013-09-11 |
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US (1) | US8297135B2 (ja) |
EP (3) | EP2042863B1 (ja) |
JP (1) | JP5289961B2 (ja) |
DE (1) | DE102005050114A1 (ja) |
WO (1) | WO2007045224A2 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US9138657B1 (en) * | 2011-07-28 | 2015-09-22 | Elemental Scientific, Inc. | Fractional-volatilization separator |
US9909957B1 (en) | 2011-12-30 | 2018-03-06 | Elemental Scientific, Inc. | Introducing hydrogen gas to an ICP instrument for enhanced detection of low-sensitivity elements |
DE102013006542B4 (de) * | 2013-04-16 | 2017-03-23 | Dräger Safety AG & Co. KGaA | Messvorrichtung, Reaktionsträger und Messverfahren |
EP2818859A1 (en) | 2013-06-28 | 2014-12-31 | Ruprecht-Karls-Universität Heidelberg | Chromatographic Device and Method |
US9322812B2 (en) | 2014-01-17 | 2016-04-26 | Institut Francais Des Sciences Et Technologies Des Transports, De L'amenagement Et Des Reseaux (Ifsttar) | Multiple sample chromatography using a stochastic injection technique |
US10184920B2 (en) | 2014-03-04 | 2019-01-22 | Tofwerk Ag | Method and apparatus for determining a chromatogram |
FR3104584B1 (fr) | 2019-12-17 | 2021-12-03 | Michelin & Cie | Composé diorganomagnésien asymétrique |
FR3104586B1 (fr) | 2019-12-17 | 2021-12-03 | Michelin & Cie | Composé diorganomagnésien asymétrique pour système catalytique |
FR3116276B1 (fr) | 2020-11-19 | 2023-11-10 | Michelin & Cie | Diorganomagnésien ayant une chaîne diénique ou oléfinique et fonctionnelle amine |
FR3116277A1 (fr) | 2020-11-19 | 2022-05-20 | Compagnie Generale Des Etablissements Michelin | Copolymères fonctionnels amine à blocs éthyléniques et diéniques |
FR3116538B1 (fr) | 2020-11-24 | 2022-11-25 | Michelin & Cie | Co-catalyseur comprenant plusieurs liaisons carbone magnésium |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3535084A (en) * | 1965-05-29 | 1970-10-20 | Katsuhisa Furuta | Automatic and continuous analysis of multiple components |
CS182967B1 (en) * | 1974-04-04 | 1978-05-31 | Jan Jokl | Dividing analysis equipment |
NL8000240A (nl) * | 1979-01-17 | 1980-07-21 | Erba Strumentazione | Verdampingsinjektor voor gaschromatografische kolommen. |
JPS6192870U (ja) * | 1984-11-22 | 1986-06-16 | ||
JPS63315923A (ja) * | 1987-06-18 | 1988-12-23 | Shimadzu Corp | マルチチャネル検出器の信号処理装置 |
GB9208313D0 (en) * | 1992-04-15 | 1992-06-03 | Pawliszyn Janusz B | Continuous separation of organic compounds from water with hollow fibre membranes and supercritical fluids |
US5538897A (en) * | 1994-03-14 | 1996-07-23 | University Of Washington | Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases |
JP3270290B2 (ja) * | 1994-04-28 | 2002-04-02 | 株式会社日立製作所 | マルチチャンネルクロマトグラムの解析方法及びデータ処理装置 |
US5431712A (en) * | 1994-05-31 | 1995-07-11 | Hewlett-Packard Company | Reconfigurable pneumatic control for split/splitless injection |
US5744654A (en) * | 1996-06-14 | 1998-04-28 | Merichem Company | Recovery of para-ethylphenol |
US5954862A (en) * | 1998-01-29 | 1999-09-21 | Hewlett-Packard Company | Sample inlet liner |
DE19817017C2 (de) * | 1998-04-17 | 2000-02-03 | Gerstel Gmbh & Co Kg | Heizpatrone für eine gaschromatographische Überführungseinrichtung |
US6352845B1 (en) * | 1999-02-10 | 2002-03-05 | Eastman Chemical Company | Corn fiber for the production of advanced chemicals and materials: separation of monosaccharides and methods thereof |
DE19949551C2 (de) * | 1999-10-14 | 2001-12-13 | Agilent Technologies Inc | Mikrofluidischer Mikrochip, Energieversorgungseinrichtung und Verfahren zum Betrieb eines mikrofluidischen Mikrochips |
US6547852B2 (en) * | 2000-01-12 | 2003-04-15 | Zoex Corporation | Transverse thermal modulation |
US6497138B1 (en) * | 2000-10-18 | 2002-12-24 | Agilent Technologies, Inc., | Multilayered gas chromatograph |
JP2004513367A (ja) * | 2000-12-19 | 2004-04-30 | テルモ フィニガン イタリア ソチエタ ペル アツィオニ | カラムクロマトグラフィー用モジュレーター |
DE10133774B4 (de) * | 2001-07-16 | 2012-03-22 | Joint Analytical Systems Gmbh | Verdampferrohr zum Verdampfen von flüssigen Proben für die Kapillar-Gaschromatographie |
WO2003067250A1 (en) * | 2002-02-04 | 2003-08-14 | Thermo Finnigan Italia S.P.A. | Method and device for comprehensive two-dimensional gas chromatography |
US7067803B2 (en) | 2002-10-11 | 2006-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Gating device and driver for modulation of charged particle beams |
JP4306481B2 (ja) * | 2004-02-06 | 2009-08-05 | 株式会社島津製作所 | クロマトグラフ分析装置 |
TWI335428B (en) | 2005-12-23 | 2011-01-01 | Apex Biotechnology Corp | Electrochemical test strip |
-
2005
- 2005-10-18 DE DE102005050114A patent/DE102005050114A1/de not_active Ceased
-
2006
- 2006-10-17 WO PCT/DE2006/001834 patent/WO2007045224A2/de active Application Filing
- 2006-10-17 US US12/090,687 patent/US8297135B2/en not_active Expired - Fee Related
- 2006-10-17 EP EP08008889.1A patent/EP2042863B1/de not_active Not-in-force
- 2006-10-17 EP EP08008888.3A patent/EP2037262B1/de not_active Not-in-force
- 2006-10-17 JP JP2008535880A patent/JP5289961B2/ja not_active Expired - Fee Related
- 2006-10-17 EP EP06805440.2A patent/EP1994403B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
DE102005050114A1 (de) | 2007-04-19 |
EP2042863B1 (de) | 2017-02-22 |
US20080295617A1 (en) | 2008-12-04 |
WO2007045224A2 (de) | 2007-04-26 |
EP1994403A2 (de) | 2008-11-26 |
EP2037262A1 (de) | 2009-03-18 |
US8297135B2 (en) | 2012-10-30 |
EP1994403B1 (de) | 2017-05-31 |
EP2037262B1 (de) | 2017-02-22 |
JP2009511924A (ja) | 2009-03-19 |
EP2042863A1 (de) | 2009-04-01 |
WO2007045224A3 (de) | 2007-08-02 |
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