JP5227167B2 - Chr8q24.21での変異体は癌のリスクを与える - Google Patents

Chr8q24.21での変異体は癌のリスクを与える Download PDF

Info

Publication number
JP5227167B2
JP5227167B2 JP2008511868A JP2008511868A JP5227167B2 JP 5227167 B2 JP5227167 B2 JP 5227167B2 JP 2008511868 A JP2008511868 A JP 2008511868A JP 2008511868 A JP2008511868 A JP 2008511868A JP 5227167 B2 JP5227167 B2 JP 5227167B2
Authority
JP
Japan
Prior art keywords
allele
cancer
prostate cancer
marker
haplotype
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2008511868A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008539782A (ja
JP2008539782A5 (enExample
Inventor
アマンダドッティー,ロウフェイ
ガドマンドソン,ユリウス
スレム,パトリック
Original Assignee
デコード・ジェネティクス・イーエイチエフ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by デコード・ジェネティクス・イーエイチエフ filed Critical デコード・ジェネティクス・イーエイチエフ
Publication of JP2008539782A publication Critical patent/JP2008539782A/ja
Publication of JP2008539782A5 publication Critical patent/JP2008539782A5/ja
Application granted granted Critical
Publication of JP5227167B2 publication Critical patent/JP5227167B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2008511868A 2005-05-18 2006-05-18 Chr8q24.21での変異体は癌のリスクを与える Expired - Fee Related JP5227167B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US68214705P 2005-05-18 2005-05-18
US60/682,147 2005-05-18
US79576806P 2006-04-28 2006-04-28
US60/795,768 2006-04-28
PCT/IS2006/000012 WO2006123369A1 (en) 2005-05-18 2006-05-18 Variants at chr8q24.21 confer risk of cancer

Publications (3)

Publication Number Publication Date
JP2008539782A JP2008539782A (ja) 2008-11-20
JP2008539782A5 JP2008539782A5 (enExample) 2009-07-30
JP5227167B2 true JP5227167B2 (ja) 2013-07-03

Family

ID=36830953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008511868A Expired - Fee Related JP5227167B2 (ja) 2005-05-18 2006-05-18 Chr8q24.21での変異体は癌のリスクを与える

Country Status (10)

Country Link
US (1) US20090317799A1 (enExample)
EP (1) EP1888772A1 (enExample)
JP (1) JP5227167B2 (enExample)
AU (1) AU2006248591B2 (enExample)
BR (1) BRPI0610794A2 (enExample)
CA (1) CA2608567A1 (enExample)
IL (1) IL187449A (enExample)
MX (1) MX2007014447A (enExample)
NZ (1) NZ563913A (enExample)
WO (1) WO2006123369A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2677994A1 (en) * 2007-02-07 2008-08-14 Decode Genetics Ehf. Genetic variants contributing to risk of prostate cancer
EP2164984A2 (en) * 2007-05-25 2010-03-24 Decode Genetics EHF. Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
US8697360B2 (en) * 2007-11-30 2014-04-15 Decode Genetics Ehf. Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition
US20090226912A1 (en) * 2007-12-21 2009-09-10 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with prostate cancer risk
US9732389B2 (en) 2010-09-03 2017-08-15 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with prostate cancer risk
US9534256B2 (en) 2011-01-06 2017-01-03 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer
WO2013065072A1 (en) * 2011-10-30 2013-05-10 Decode Genetics Ehf Risk variants of prostate cancer
KR101944927B1 (ko) 2016-03-24 2019-02-07 서울대학교산학협력단 전립선암과 관련된 단일염기다형성 및 이를 이용한 유전 위험도 점수의 개발
KR20250074712A (ko) 2023-11-15 2025-05-28 주식회사 바스젠바이오 전립선암 발병의 위험도를 예측하기 위한 조성물 및 이를 이용한 방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
FI843529A0 (fi) 1983-01-10 1984-09-10 Gen Probe Inc Foerfarande foer detektering, identifiering och kvantitering av organismer och virus.
US5288611A (en) 1983-01-10 1994-02-22 Gen-Probe Incorporated Method for detecting, identifying, and quantitating organisms and viruses
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5288644A (en) 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
DE69132531T2 (de) 1990-12-06 2001-09-13 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Verbindungen und ihre Verwendung in einer binären Synthesestrategie
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
EP0655090B1 (en) 1992-04-27 2000-12-27 The Trustees Of Dartmouth College Detection of gene sequences in biological fluids
WO1999032644A2 (en) * 1997-12-22 1999-07-01 Genset Prostate cancer gene

Also Published As

Publication number Publication date
JP2008539782A (ja) 2008-11-20
CA2608567A1 (en) 2006-11-23
AU2006248591A1 (en) 2006-11-23
BRPI0610794A2 (pt) 2010-11-09
AU2006248591A9 (en) 2006-11-23
NZ563913A (en) 2010-03-26
AU2006248591B2 (en) 2012-02-23
IL187449A (en) 2014-03-31
AU2006248591A2 (en) 2006-11-23
MX2007014447A (es) 2008-04-16
WO2006123369A1 (en) 2006-11-23
WO2006123369A8 (en) 2007-01-04
EP1888772A1 (en) 2008-02-20
US20090317799A1 (en) 2009-12-24
IL187449A0 (en) 2008-02-09

Similar Documents

Publication Publication Date Title
JP5631000B2 (ja) Chr8q24.21上の癌感受性変異体
EP2115171B1 (en) Genetic variants contributing to risk of prostate cancer
JP5676245B2 (ja) 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのchr2およびchr16の遺伝的変異
JP2010527603A (ja) 乳癌のリスクアセスメント、診断、予後診断および治療における使用のためのマーカーとしてのCHR5p12および10q26上の遺伝的変異
CA2734123A1 (en) Genetic variants predictive of cancer risk
CA2729931A1 (en) Genetic variants predictive of cancer risk in humans
JP2011530306A (ja) 甲状腺癌のリスクアセスメントに有用な遺伝的変異
JP2011527565A (ja) 乳癌のリスクアセスメントのための遺伝的変異
EP2451975A1 (en) Genetic variants contributing to risk of prostate cancer
IL187449A (en) And variants of chr8q24.21 as a cancer risk identification
WO2009047809A2 (en) Sequence variants for inferring human pigmentation patterns
US20090226912A1 (en) Methods and compositions for correlating genetic markers with prostate cancer risk
WO2009069152A2 (en) Genetic variants on chr hq and 6q as markers for prostate and colorectal cancer predisposition
CA2556635A1 (en) Methods for diagnosing and characterizing breast cancer and susceptibility to breast cancer
WO2010131268A1 (en) Genetic variants for basal cell carcinoma, squamous cell carcinoma and cutaneous melanoma
WO2010033825A2 (en) Genetic variants associated with abdominal aortic aneurysms

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090518

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090518

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20110914

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110926

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111108

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120203

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120210

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120508

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121023

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130123

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20130214

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130315

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20160322

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees