JP5219955B2 - Analyzing device and method for driving the stirring device - Google Patents

Description

  The present invention relates to an analyzer equipped with a stirrer that stirs a specimen or a reagent in a non-contact manner using sound waves and a method for driving the stirrer.

  2. Description of the Related Art Conventionally, an analyzer uses a stirring device that stirs a sample or reagent in a non-contact manner using sound waves in order to avoid contamination when the sample or reagent is stirred (see, for example, Patent Document 1).

JP 2002-250732 A

  By the way, the analyzer performs agitation of the liquid during the dispensing operation in which the conveyance of the reaction container is stopped by the rotation of the cuvette wheel. For this reason, in the analyzer, the liquid stirring time is limited. On the other hand, liquids to be stirred have a wide range of liquid properties ranging from those having low viscosity and easy stirring to those having high viscosity and difficult to stir. For this reason, if a liquid with a wide range of properties is stirred with a single stirrer for a certain period of time according to the properties of the liquid, the load on the sound wave generating means increases, and it is technical from the viewpoint of control of the drive system. There is a problem that is difficult. In this case, it may be possible to stir the liquid by using a plurality of stirring devices and individually changing the stirring conditions, but there is a problem that complicated control is required.

  The present invention has been made in view of the above, and provides an analysis apparatus that can have a simple structure and satisfy desired stirring conditions even if a plurality of stirring apparatuses are provided, and a method for driving the stirring apparatus. For the purpose.

  In order to solve the above-described problems and achieve the object, the analysis apparatus of the present invention is an analysis including a plurality of stirring devices that stir the liquid held in the container by sound waves generated by the sound wave generating means attached to the container. The stirring device has one or more rated stirring devices with constant stirring conditions and one variable stirring device capable of adjusting the stirring conditions, and the one or more rated stirring devices according to analysis items. Identify one or more agitation devices to be driven from among the agitation device and the variable agitation device, and specify the agitation conditions of the variable agitation device when the specified one or more agitation devices include the variable agitation device And the liquid is agitated by the one or more agitation devices specified by the control means.

  In the analysis device according to the present invention, the stirring condition of the variable stirring device is set in advance according to the analysis item.

  In the analyzer according to the present invention, the stirring condition of the variable stirrer is determined by an analysis test performed in advance using a calibrator.

  In order to solve the above-described problems and achieve the object, according to the analysis device of the present invention, the variable stirring device is driven by the total stirring power required for stirring the liquid according to the analysis item and the 1 Or it drives so that the difference with the rated supply electric power supplied to the 1 or 2 or more rated stirring apparatus contained in 2 or more stirring apparatuses may be supplemented.

  In order to solve the above-described problems and achieve the object, the stirrer driving method of the analyzer of the present invention stirs the liquid held in the container by the sound wave generated by the sound wave generating means attached to the container. A stirrer driving method for an analyzer equipped with a plurality of stirrers, wherein one or two or more rated stirrers driven under rated stirring conditions are driven to stir the liquid, and variable agitation A variable stirring step of driving one variable stirring device under conditions to stir the liquid, and a control step of specifying at least one of the rated stirring step or the variable stirring step according to an analysis item, According to the analysis item, the liquid is stirred by at least one of the rated stirring process and the variable stirring process.

  Moreover, the stirring device driving method of the analyzer according to the present invention is characterized in that, in the above invention, the stirring conditions of the variable stirring device are preset according to the analysis item.

  In addition, in the above-described invention, the stirrer driving method of the analyzer according to the present invention is characterized in that the stirrer condition of the variable stirrer is determined by an analysis test performed in advance using a calibrator.

  Moreover, the stirring device driving method of the analyzer of the present invention is the above-described invention, wherein the variable stirring device is driven by the total stirring power required for stirring the liquid according to the analysis item and the 1 or 2 driven. It is characterized by being driven so as to compensate for the difference from the rated supply power supplied to one or two or more rated stirring devices included in the above stirring device.

  According to the present invention, the driving conditions of one or more rated agitating devices are made constant, and the driving conditions of one variable agitating device are made variable. There is an effect that the condition can be satisfied.

FIG. 1 is a schematic configuration diagram illustrating the automatic analyzer according to the first embodiment. FIG. 2 is a block diagram showing a schematic configuration of a variable stirring device used in the automatic analyzer of FIG. 1 together with a perspective view of a reaction vessel. FIG. 3 is a block diagram showing a schematic configuration of a rated stirring device used in the automatic analyzer of FIG. 1 together with a perspective view of a reaction vessel. FIG. 4 is a flowchart for explaining the method for driving the stirring device of the analyzer of the present invention. FIG. 5 is a diagram for explaining control when driving the variable agitator.

  DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiments according to an analysis apparatus and a stirring apparatus driving method of the present invention will be described below in detail with reference to the drawings. FIG. 1 is a schematic configuration diagram showing an automatic analyzer of the present invention. FIG. 2 is a block diagram showing a schematic configuration of a stirring device used in the automatic analyzer of FIG. 1 together with a perspective view of a reaction vessel.

  As shown in FIG. 1, the automatic analyzer 1 includes reagent tables 2 and 3, a reaction table 4, a specimen container transfer mechanism 8, an optical measurement device 12, a cleaning mechanism 13, a control unit 15, a variable stirring device 20, and a rated stirring device. 30 and 31 are provided.

  As shown in FIG. 1, each of the reagent tables 2 and 3 is rotated by driving means to convey the reagent container 2a holding the first reagent and the reagent container 3a holding the second reagent in the circumferential direction.

  As shown in FIG. 1, the reaction table 4 has a plurality of reaction vessels 5 arranged in the circumferential direction, and rotates counterclockwise while keeping the plurality of reaction vessels 5 at a predetermined temperature (for example, 37 ° C.). The reaction vessel 5 is transported along the circumferential direction. The reaction table 4 rotates, for example, in one cycle (1 turn-1 reaction vessel) / 4, and in 4 cycles (1 turn-1 reaction vessel). The plurality of reaction vessels 5 arranged in the reaction table 4 are transported along the circumferential direction by intermittent rotation of the reaction table 4, while dispensing the reagent, sample dispensing, stirring of the liquid sample containing the reagent and the sample, Reagents, specimens, and reaction solutions are optically measured and washed. The reaction table 4 is provided with reagent dispensing mechanisms 6 and 7, a sample dispensing mechanism 11, a variable stirring device 20, and rated stirring devices 30 and 31 in the vicinity.

  The reaction vessel 5 is a very small cuvette having a capacity of several μL to several hundred μL, and is a transparent material that transmits 80% or more of the light contained in the analysis light emitted from the light source 12a of the optical measuring device 12, for example, heat resistant Glass containing glass, synthetic resins such as cyclic olefin and polystyrene are used. The reaction vessel 5 has a sound wave generating element 28 attached to the side wall 5a (see FIG. 2), and constitutes the stirring device 20 and the rated stirring devices 30 and 31 together with the sound wave generating element 28. The reaction container 5 is disposed on the reaction table 4 with the sound wave generating element 28 facing outward in the radial direction. The reagent dispensing mechanisms 6 and 7 provided in the vicinity of the outer periphery of the reaction table 4 cause the first reagent from the reagent containers 2a and 3a. And the second reagent are sequentially dispensed.

  As shown in FIG. 1, the reagent dispensing mechanisms 6 and 7 are provided with probes 6b and 7b for dispensing reagents on arms 6a and 7a that rotate in the direction of the arrow in the horizontal plane, respectively. It has a probe cleaning tank (not shown) for cleaning 7b. At this time, the reagent dispensing mechanism 6 dispenses the first reagent from the reagent container 2a to the reaction container 5, and the reagent dispensing mechanism 7 dispenses the second reagent from the reagent container 3a to the reaction container 5.

  As shown in FIG. 1, the sample container transfer mechanism 8 transfers a plurality of racks 10 arranged in the feeder 9 while advancing one by one along the arrow direction. The rack 10 holds a plurality of sample containers 10a containing samples. Here, the sample container 10a is sampled by the sample dispensing mechanism 11 having the drive arm 11a and the probe 11b that rotate in the horizontal direction each time the step of the rack 10 transferred by the sample container transfer mechanism 8 stops. Is dispensed into each reaction vessel 5. For this reason, the specimen dispensing mechanism 11 has probe cleaning means for cleaning the probe 11b with cleaning water.

  The optical measurement device 12 emits analysis light for analyzing the liquid in the reaction vessel 5 in which the reagent and the sample have reacted. As shown in FIG. 1, the optical measurement device 12 includes a light source 12a, a spectroscopic unit 12b, and a light receiving unit 12c. Have. The analysis light emitted from the light source 12a passes through the liquid in the reaction vessel 5 and is received by the light receiving unit 12c provided at a position facing the spectroscopic unit 12b. The light receiving unit 12 c is connected to the control unit 15 and outputs a light amount signal corresponding to the light amount of the received analysis light to the control unit 15. Here, when analyzing one specimen, the reaction container 5 measures the dispensed reagent and a reaction solution obtained by reacting the specimen with the specimen a plurality of times.

  The cleaning mechanism 13 optically measures the reaction liquid by repeating the operation of sucking the detergent discharged to the reaction container 5 by the nozzle and the operation of sucking the cleaning water discharged to the reaction container 5 after the detergent suction by the nozzle a plurality of times. The reaction vessel 5 that has been finished is washed.

  For example, a microcomputer or the like is used as the control unit 15 and is connected to each component of the automatic analyzer 1. The controller 15 controls the operation of each component, and the amount of light emitted from the light source 12a and the amount of light received by the light receiver 12c. Based on the absorbance of the liquid in the reaction container 5 based on the above, the component concentration of the specimen is analyzed. The control unit 15 executes the analysis operation while controlling the operation of each component of the automatic analyzer 1 based on the analysis request information input from the input unit 17 such as a keyboard or the host computer, and also the analysis result and warning information. In addition, various information based on a display command input from the input unit 17 is displayed on the display unit 18 such as a display panel. At this time, the control unit 15 identifies which agitator is to be driven from among the variable agitator 20 or the rated agitator 30, 31 according to the analysis item read from the analysis information based on the analysis request, and has been identified. When the variable stirring device 20 is included in the stirring device, the stirring condition of the variable stirring device 20 is specified. Combinations and stirring conditions for driving the stirring device are registered in the control unit 15 in advance as a table or the like according to the analysis item.

  As shown in FIG. 1, the variable stirring device 20 and the rated stirring devices 30 and 31 are disposed in the vicinity of the outer periphery of the reaction table 4. The variable agitation device 20 and the rated agitation devices 30 and 31 are agitation devices that drive the sound wave generating element 28 and stir the liquid such as the specimen and the reagent held in the reaction vessel 5 in a non-contact manner by the generated sound wave. At this time, the stirring conditions of the variable stirring device 20 can be changed, and the stirring conditions of the rated stirring devices 30 and 31 are set to be constant. The variable stirring device 20 and the rated stirring devices 30 and 31 have a power transmission body 21 and an arrangement determining member 22. Under the control of the control unit 15, the operation of the variable stirring device 20 is controlled by the stirring control unit 23 (see FIG. 2), and the rated stirring devices 30, 31 are operated by the stirring control unit 33 (see FIG. 3). Is controlled.

  Here, regarding the variable agitator 20 and the rated agitators 30 and 31, the agitation condition refers to the driving condition of the sound wave generating element 28, and mainly refers to the supply power and the supply time thereof. However, in addition to the stirring conditions, for example, the characteristics (frequency, intensity, phase, wave characteristics) of the drive signal that drives the sound wave generating element 28, waveforms (sine wave, triangular wave, rectangular wave, burst wave, etc.) Alternatively, modulation (amplitude modulation, frequency modulation) or the like is included. In this case, the variable agitation device 20 is driven under variable agitation conditions that adjust the supplied power between 0 and 100%. On the other hand, the rated agitation devices 30 and 31 are driven under the rated agitation conditions that keep the supplied power constant (= 100%).

  Then, the stirring conditions of the variable stirring device 20 are set in advance for each analysis item through an analysis test using a calibrator and stored in the signal control unit 24 for each analysis item. This is because the amount of the reagent is overwhelmingly larger than the amount of the specimen when viewed with respect to the liquid to be agitated dispensed into the reaction vessel 5. For this reason, when the analysis item is determined, not only the amount of liquid to be agitated but also the nature of the liquid whether or not it is easy to agitate, that is, the agitation conditions including the required supply power of the sound wave generating element 28 necessary for agitation. Determined. Therefore, the stirring conditions are set for each analysis item and stored in the control unit 15 in advance.

  Here, the standard sample and the reagent are included in the calibrator used when setting the stirring conditions.

  The power transmission body 21 supplies electric power supplied from a high-frequency AC power source of several MHz to several hundreds of MHz to the sound wave generating element 28, and is pushed out during power supply to be in contact with the input terminal 28c of the sound wave generating element 28. Contact (not shown). As shown in FIG. 1, the power transmission body 21 is supported by the arrangement determining member 22, and is arranged so as to face the reaction container 5 in the horizontal direction at positions facing each other on the outer periphery of the reaction table 4.

  As for the arrangement | positioning determination member 22, the relative arrangement | positioning in the circumferential direction and radial direction of the reaction table 4 of the power transmission body 21 and the sound wave generation element 28 is adjusted beforehand. When the arrangement determining member 22 pushes the contact from the power transmission body 21 toward the reaction table 4, the contact comes into contact with the input terminal 28 c of the sound wave generation element 28, and power is transmitted from the power transmission body 21 to the sound wave generation element 28. Supplied.

  The agitation control unit 23 has been conventionally used, and as shown in FIG. 2, the agitation control unit 23 sets the agitation conditions according to the sample information such as the test item and the liquid amount of the sample input from the input unit 17 via the control unit 15. Control means for adjusting and controlling the driving of the sound wave generating element 28, and includes a signal control unit 24, a signal generation circuit 25, an amplification circuit 26, and a detection circuit 27.

  The signal control unit 24 uses electronic control means (CPU) incorporating a memory and a timer, and controls the operation of the communication circuit 22, the signal generation circuit 25, the amplification circuit 26 and the detection circuit 27 in cooperation with the control unit 15. To do. Here, the above-described stirring conditions for each analysis item are stored in the signal control unit 24 in advance. The signal control unit 24 controls the voltage, current, application time, and the like of the drive signal output from the amplification circuit 26 to the sound wave generation element 28 by outputting the control signal Sc to the signal generation circuit 25. Thereby, the signal control unit 24, for example, the characteristics (frequency, intensity, phase, wave characteristics), waveform (sine wave, triangular wave, rectangular wave, burst wave, etc.) or modulation (amplitude) of the sound wave generated by the sound wave generating element 28. Modulation, frequency modulation), the power of the drive signal input to the sound wave generation element 28, the drive time of the sound wave generation element 28, and the like. Further, the signal control unit 24 can change the frequency and oscillation time of the high-frequency signal oscillated by the signal generation circuit 25 according to a built-in timer.

  The signal generation circuit 25 has an oscillation circuit that can change the oscillation frequency and control the gain based on the control signal input from the signal control unit 24. For example, the signal generation circuit 25 has a drive signal Sd (analog) of 50 to 80 MHz. ) To the amplifier circuit 26. When the drive signal Sd is output to the amplifier circuit 26, the signal generation circuit 25 outputs a lock signal SL indicating the frequency of the output drive signal Sd to the signal control unit 24.

  The amplification circuit 26 amplifies the drive signal Sd (analog) of the sound wave generation element 28 input from the signal generation circuit 25 with a preset amplification factor, and supplies predetermined drive power to the sound wave generation element 28. When the driving power is supplied to the sound wave generating element 28, the amplifier circuit 26 outputs a lock signal SL indicating the frequency of the driving power to the signal generating circuit 25. The amplifier circuit 26 also detects a traveling wave signal output to the sound wave generating element 28, a temperature information signal of the sound wave generating element 28 reflected from the sound wave generating element 28, and an element signal (analog signal) Sdv including the reflected wave signal. Output to the circuit 27.

  The detection circuit 27 detects the traveling wave (analog signal) of the driving power output from the amplification circuit 26 as power data, is reflected from the sound wave generation element 28, and is input through the amplification circuit 26. These temperature information signals and reflected wave signals (analog signals) are detected as reflected power data, and these data signals Sda are output to the signal control unit 24 and stored.

  As shown in FIG. 2, the sound wave generating element 28 has a vibrator 28b made of a comb-shaped electrode (IDT) formed on the surface of a piezoelectric substrate 28a made of, for example, lithium niobate (LiNbO3). The vibrator 28b is a sound generation unit that converts a drive signal input from the stirring control unit 21 into a surface acoustic wave (sound wave), and a plurality of fingers constituting the vibrator 28b are arranged along the longitudinal direction of the piezoelectric substrate 28a. Has been. The sound wave generating element 28 is connected to the stirring control unit 21 by a set of input terminals 28c. The vibrator 28b is connected to the input terminal 28c by a bus bar 28d. The sound wave generating element 28 is attached to the side wall 5a of the reaction vessel 5 through an acoustic matching layer such as an epoxy resin.

  Since the rated agitating devices 30 and 31 have the same configuration, the rated agitating device 30 will be described. And the rated stirring apparatus 31 uses the same code | symbol for the component same as the rated stirring apparatus 30 in the following description.

  The rated stirring device 30 is driven under a rated stirring condition in which the supplied power is kept constant (= 100%) by the stirring control unit 33 shown in FIG. The stirring control unit 33 is configured simply because it is driven under the rated stirring conditions, and includes a signal generation circuit 35 and an amplification circuit 36. For this reason, the agitation control unit 33 has a simpler configuration than the agitation control unit 23, and accordingly, the control is easier than the agitation control unit 23.

  The signal generation circuit 35 has an oscillation circuit capable of changing the oscillation frequency based on the control signal input from the control unit 15 and controlling the gain. For example, the signal generation circuit 35 generates a drive signal (analog) of 50 to 80 MHz. Output to the amplifier circuit 36.

  The amplification circuit 36 amplifies the drive signal (analog) of the sound wave generation element 28 input from the signal generation circuit 35 with a preset amplification factor, and supplies predetermined drive power to the sound wave generation element 28.

  The automatic analyzer 1 configured as described above operates under the control of the control unit 15, and the reagent dispensing mechanism 6 is supplied to the plurality of reaction containers 5 conveyed along the circumferential direction by the rotating reaction table 4. , 7 and the specimen dispensing mechanism 11 sequentially dispense the first reagent, the second reagent, and the specimen, and the reagents and specimen dispensed by the variable agitator 20 and the rated agitators 30, 31 are sequentially agitated. .

  Then, when the reaction vessel 5 in which the reagent and the sample are stirred passes through the optical measuring device 12, the optical characteristics of the reaction solution are measured by the light receiving unit 12c, and the component concentration and the like are analyzed by the control unit 15. Then, after the photometry of the reaction liquid is completed, the reaction container 5 is washed by the washing mechanism 13 and then used again for analyzing the specimen.

  At this time, in the automatic analyzer 1, one or two or more stirring devices to be driven are specified from the variable stirring device 20 and the rated stirring devices 30 and 31 according to the analysis item by the control unit 15 which is a control means. The liquid containing the reagent or specimen dispensed into the reaction vessel 5 is stirred by the specified one or more stirring devices. Hereinafter, the stirring device driving method of the analyzer of the present invention will be described with reference to the flowchart shown in FIG.

  First, the control unit 15 acquires analysis request information (step S100). The analysis request information uses analysis request information input from the input unit 17 such as a keyboard or analysis request information input from the host computer. Next, the control unit 15 acquires an analysis item from the acquired analysis request information (step S102). Next, the stirrer to be driven is specified from the variable stirrer 20 or the rated stirrers 30 and 31 according to the analysis item (step S104). At this time, the control unit 15 specifies from a pre-registered table or the like.

  Table 1 shows an example of a table for specifying the stirring device to be driven at this time. At this time, Table 1 shows the difficulty of stirring, the variable stirring device 20 to be driven or the combination of the rated stirring devices 30 and 31, and the total stirring power ratio supplied to the combined stirring devices. The difficulty of stirring is divided in the order of A being very difficult to stir, B being difficult to stir, C being slightly stirrable, D being normal, E being slightly stirrable, and F being stirrable. The total stirring power ratio is the sum of the ratios expressed as 1 when the power supplied to the variable stirring device 20 and the rated stirring devices 30 and 31 is 100%.

  As shown in Table 1, the control unit 15 specifies the stirring device to be driven according to the analysis item, that is, the difficulty level of stirring, and when the variable stirring device 20 is specified, the supply power is set to 0 to 100. Adjust between%. At this time, as shown in FIG. 5, the control unit 15 includes the total stirring power necessary for stirring the liquid according to the analysis item, and one or two or more included in the one or two or more stirring devices to be driven. The power is continuously adjusted so as to compensate for the difference from the rated supply power supplied to the rated agitator, and the drive of the variable agitator 20 is controlled.

  In this drive control, when the stirring difficulty is Gs, the control unit 15 drives the rated stirring device 30 alone (power supply 100%), and when the stirring difficulty is Gw, Only 31 is driven (power supply 100%). Then, when the supply power supplied to the variable stirring device 20 reaches 100%, the control unit 15 drives the rated stirring device 30 and the rated stirring device 31, and calculates the difference between the total stirring power and the rated supply power. The variable agitator 20 is driven and controlled to compensate.

  The control unit 15 determines whether or not the rated stirring devices 30 and 31 are included in the specific target (step S106). As a result of the determination, if the specific target includes the rated stirring devices 30 and 31 (step S106, Yes), the control unit 15 determines whether or not the specific target includes the variable stirring device 20 (step S108). As a result of the determination, when there is the variable stirring device 20 as the specific target (Step S108, Yes), the control unit 15 selects the variable stirring device 20 as the specific target and the rated stirring from the variable stirring device 20 and the rated stirring devices 30 and 31. The device is driven (step S110). Thereby, the liquid hold | maintained at the reaction container 5 is stirred by the variable stirring apparatus 20 of a specific object, and a rated stirring apparatus.

  After the stirring is completed, the control unit 15 determines whether or not the analysis of all the samples has been completed (step S112). This determination is performed based on the previously acquired analysis request information. As a result of the determination, when the analysis has not been completed for all the samples (step S112, No), the control unit 15 returns to step S104 and executes the subsequent steps. When analysis has been completed for all the samples (step S112, Yes), the control unit 15 ends the stirring device driving method of the analyzer.

  On the other hand, when the variable stirring device 20 is not included in the specific target (No at Step S108), the control unit 15 drives the rated stirring device as the specific target among the rated stirring devices 30 and 31 (Step S114). Thereby, the liquid hold | maintained at the reaction container 5 with the rated stirring apparatus of specific object is stirred. After the stirring is completed, the control unit 15 proceeds to step S112.

  Moreover, as a result of the determination in step S106, when there is no rated stirring device 30, 31 in the specific target (No in step S106), the control unit 15 determines whether there is the variable stirring device 20 in the specific target (step). S116). As a result of the determination, when the variable stirring device 20 is not included in the specific target (No at Step S116), the control unit 15 proceeds to Step S112. On the other hand, when there is the variable stirring device 20 as the specific target (step S116, Yes), the control unit 15 drives the variable stirring device 20 (step S118). Thereby, the liquid hold | maintained at the reaction container 5 with the variable stirring apparatus 20 of specific object is stirred. After completion of the stirring and stirring, the control unit 15 proceeds to Step S112.

  In the present invention, the liquid held in the reaction vessel 5 is stirred according to the properties of the liquid by one or more stirring devices specified from the variable stirring device 20 and the rated stirring devices 30 and 31 as described above. At this time, the automatic analyzer 1 includes rated stirring devices 30 and 31 having constant stirring conditions and a variable stirring device 20 capable of adjusting the stirring conditions. For this reason, even if the automatic analyzer 1 includes a plurality of stirring devices, the structure is simple and a desired stirring condition can be satisfied.

  Moreover, the automatic analyzer 1 can make the rated agitators 30 and 31 out of the three agitators to be used simpler in structure than the variable agitator 20 and less expensive. That is, the rated stirring devices 30 and 31 can be manufactured at half the price of the variable stirring device 20. At this time, for example, if the variable stirring device 20 is used, the price of the rated stirring devices 30 and 31 is 0.5 Pm, so the total price of the three stirring devices is 2 Pm (= Pm + 0.5 Pm × 2). Therefore, the price (= 2 Pm) of the variable agitator 20 and the rated agitators 30 and 31 is approximately 33% less than that when the three agitators are the variable agitator 20 (= 3 Pm).

  As described above, the analysis device and the stirring device driving method of the present invention have a simple structure and a desired stirring condition because the driving conditions of a plurality of rated stirring devices are fixed even if a plurality of stirring devices are provided. This is useful for stirring liquids under pressure.

DESCRIPTION OF SYMBOLS 1 Automatic analyzer 2,3 Reagent table 4 Reaction table 5 Reaction container 6,7 Reagent dispensing mechanism 8 Specimen container transfer mechanism 9 Feeder 10 Rack 11 Specimen dispensing mechanism 12 Optical measuring device 13 Cleaning mechanism 15 Control part 20 Variable stirring apparatus DESCRIPTION OF SYMBOLS 21 Power transmission body 22 Arrangement | positioning determination member 23 Agitation control part 24 Signal control part 25 Signal generation circuit 26 Amplification circuit 27 Detection circuit 28 Sound wave generation element 30, 31 Rated stirring apparatus 33 Agitation control part 35 Signal generation circuit 36 Amplification circuit

Claims (8)

An analyzer comprising a plurality of stirring devices for stirring the liquid held in the container by sound waves generated by sound wave generating means attached to the container,
The stirring device has one or more rated stirring devices in which stirring conditions are constant, and one variable stirring device capable of adjusting the stirring conditions,
When one or more stirring devices to be driven are specified from the one or more rated stirring devices and the variable stirring device according to the analysis item, and the variable stirring device is included in the specified one or more stirring devices And a control means for specifying the stirring conditions of the variable stirring device,
The analysis device characterized in that the liquid is stirred by the one or more stirring devices specified by the control means.   The analysis apparatus according to claim 1, wherein the stirring condition of the variable stirring apparatus is preset according to the analysis item.   The analysis apparatus according to claim 2, wherein the stirring condition of the variable stirring apparatus is determined by an analysis test performed in advance using a calibrator.   The variable stirrer has a total stirring power required for stirring the liquid according to the analysis item and a rating supplied to the one or more rated stirrers included in the one or more stirrers to be driven. The analyzer according to claim 3, wherein the analyzer is driven so as to compensate for a difference from the supplied power. A stirrer driving method of an analyzer comprising a plurality of stirrers that stir the liquid held in the container by sound waves generated by sound wave generating means attached to the container,
A rated agitation step of agitating the liquid by driving one or more rated agitation devices driven under rated agitation conditions;
A variable agitation step of agitating the liquid by driving one variable agitation device under variable agitation conditions;
A control step that identifies at least one of the rated stirring step or the variable stirring step according to an analysis item;
And stirring the liquid by at least one of the rated stirring step and the variable stirring step according to the analysis item.   The method for driving a stirrer of an analyzer according to claim 5, wherein a stirring condition of the variable stirrer is preset according to the analysis item.   The method for driving a stirrer of an analyzer according to claim 6, wherein a stirring condition of the variable stirrer is determined by an analysis test performed in advance using a calibrator.   The variable agitation device includes a total agitation power necessary for agitation of the liquid according to the analysis item and a rated supply supplied to one or more rated agitation devices included in the one or more agitated devices to be driven. It drives so that the difference with electric power may be supplemented, The stirring apparatus drive method of the analyzer of Claim 7 characterized by the above-mentioned.

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