JP5219610B2

JP5219610B2 - Equipment for transporting and administering therapeutic substances

Info

Publication number: JP5219610B2
Application number: JP2008122814A
Authority: JP
Inventors: 真法前田; 秀典宅島; 光夫岡野; 雅之大和; 洋伊関; 亮一中村; 恭正大貫; 正人神崎; 孝司鈴木; 慈長井
Original assignee: Hoya Corp; Tokyo Womens Medical University
Current assignee: Hoya Corp; Tokyo Womens Medical University
Priority date: 2007-05-22
Filing date: 2008-05-09
Publication date: 2013-06-26
Anticipated expiration: 2028-05-09
Also published as: JP2009000511A

Description

本発明は、シート状の治療用物質を患部まで運搬して投与する器具に関する。 The present invention relates to a device for transporting and administering a sheet-like therapeutic substance to an affected area.

呼吸器系の手術において縫合部分の補強や気漏防止のために、ポリグリコール酸などの生体内分解吸収性素材からなるシート状（生地状）物質を臓器に貼り付ける治療が行われている。また、非特許文献１のように、患者の自己細胞をシート状に培養、再生し、この細胞シートを患部に移植する治療技術も提案されている。近年では、人体に対する低侵襲な手術方法として内視鏡下手術が広く用いられており、上記のようなシート状治療用物質の運搬や投与の手段として、主に内視鏡の鉗子が用いられてきた。 In respiratory surgery, in order to reinforce a sutured part and prevent air leakage, a treatment in which a sheet-like (fabric) substance made of a biodegradable and absorbable material such as polyglycolic acid is attached to an organ is performed. Further, as in Non-Patent Document 1, a treatment technique for culturing and regenerating a patient's own cells into a sheet and transplanting the cell sheet to an affected area has also been proposed. In recent years, endoscopic surgery has been widely used as a minimally invasive surgical method for the human body, and endoscopic forceps are mainly used as a means for transporting and administering the above-mentioned sheet-like therapeutic substance. I came.

しかし、脆弱であったり自己密着を起こしやすいシート状の治療用物質を、鉗子によって患部まで運搬し広げて正確に移植するには高度な手技が必要とされ、作業性の改善が望まれていた。そこで出願人は、シート状治療用物質を支持する弾性変形可能なシート支持体に対して、内部に供給される流体の流体圧の変化によって、平面状の展開形状と筒状の収納形状への変形動作と、基端部の曲げ動作とを行わせる治療用物質の運搬投与器具を提案した（特許文献１）。
「術中気漏に対する細胞シートによる閉鎖の試み」日本再生医療学会第3回日本再生医療学会総会抄録集、２００３年特願２００７−１０４５２ However, advanced techniques are required to transport a fragile or self-adhering sheet-like therapeutic substance to the affected area with forceps and accurately transplant it, and improvement in workability has been desired. . Therefore, the applicant applies to the elastically deformable sheet support that supports the sheet-like therapeutic substance, by changing the fluid pressure of the fluid supplied to the inside, into a flat deployed shape and a cylindrical storage shape. The therapeutic substance delivery administration device which performs a deformation | transformation operation | movement and the bending operation | movement of a base end part was proposed (patent document 1).
"Trial of cell sheet closure for intraoperative air leak" Japanese Society of Regenerative Medicine, 3rd Annual Meeting of Japan Society of Regenerative Medicine, 2003 Japanese Patent Application No. 2007-10452

特許文献１の運搬投与器具は、その構造上、シート支持体の内部に微細な流体流路を設け、かつ流体の流通を厳密に管理する必要があり、生産コストや駆動時の信頼性において改善の余地があった。よって本発明は、従来に比して低コストに得られると共に信頼性に優れ、簡単かつ確実にシート状の治療用物質を患部に投与することができる運搬投与器具を提供することを目的とする。 The transport and administration device of Patent Document 1 is required to provide a fine fluid flow path inside the sheet support and to strictly manage the flow of the fluid because of its structure, improving the production cost and reliability during driving. There was room for. Accordingly, an object of the present invention is to provide a transport administration device that can be obtained at low cost as compared with the prior art, has excellent reliability, and can easily and reliably administer a sheet-like therapeutic substance to an affected area. .

本発明の治療用物質の運搬投与器具は、その一態様では、円筒状の外筒と、該外筒内に軸線方向へ摺動可能に支持されたスライド部材と、シート状の治療用物質を支持して上記スライド部材の先端部に設けられ、外筒の先端部から突出された自由状態では平面状の展開形状に保たれ、スライド部材の摺動移動に応じて外筒の内部方向に移動されたときに該外筒の先端部に当接して筒状に変形しながら外筒内に収納されるシート支持部材とを有し、シート支持部材はスライド部材に対して外筒の径方向に着脱可能であり、通常使用状態では、該シート支持部材の着脱が外筒の内周面によって規制される範囲内にスライド部材の可動域を制限する移動制限手段を備えていることを特徴としている。 In one aspect, the therapeutic substance delivery administration device of the present invention comprises a cylindrical outer cylinder, a slide member supported so as to be slidable in the axial direction in the outer cylinder, and a sheet-like therapeutic substance. It is supported and provided at the tip of the slide member, and in a free state protruding from the tip of the outer cylinder, it is maintained in a flat developed shape and moves inward of the outer cylinder according to the sliding movement of the slide member is possess a seat support member that is housed in the outer tube while being deformed in contact with the tubular at the distal end of the outer cylinder when the sheet supporting member in the radial direction of the outer cylinder relative to the slide member It is detachable and, in a normal use state, is provided with a movement restricting means for restricting a movable range of the slide member within a range in which attachment / detachment of the sheet support member is restricted by an inner peripheral surface of the outer cylinder . .

シート支持部材は、シート状の治療用物質を支持する支持面部と、該支持面部からスライド部材との接続部へ向けて徐々に横幅を狭くする幅徐変部とを有し、外筒から突出された展開状態から外筒の内部方向に移動されるとき、幅徐変部と外筒の先端部との当接によって、シート支持部材を筒状に変形させるとよい。この場合、外筒の先端部に、該外筒の軸線と直交する平面に対して非平行な傾斜端面を形成すると、シート支持部材を筒状に変形させやすくなる。 The sheet support member has a support surface portion for supporting the sheet-like therapeutic substance, and a width gradually changing portion that gradually narrows the lateral width from the support surface portion toward the connection portion with the slide member, and protrudes from the outer cylinder. When the sheet is moved from the developed state toward the inside of the outer cylinder, the sheet supporting member may be deformed into a cylindrical shape by contact between the gradually changing width portion and the tip of the outer cylinder. In this case, if an inclined end surface that is not parallel to a plane orthogonal to the axis of the outer cylinder is formed at the tip of the outer cylinder, the sheet support member can be easily deformed into a cylindrical shape.

本発明の治療用物質の運搬投与器具は、別の態様では、円筒状の外筒と、該外筒内に軸線方向へ摺動可能に支持されたスライド部材と、シート状の治療用物質を支持して上記スライド部材の先端部に設けられ、外筒の先端部から突出された自由状態では平面状の展開形状に保たれ、スライド部材の摺動移動に応じて外筒の内部方向に移動されたときに該外筒の先端部に当接して筒状に変形しながら外筒内に収納されるシート支持部材とを有し、外筒の内部に、シート支持体を支持する外筒内部の表面積を増大させる隔壁部を形成することにより、より幅の広いシート支持部材を収納することが可能となる。 In another aspect, the therapeutic substance delivery administration device of the present invention comprises a cylindrical outer cylinder, a slide member supported so as to be slidable in the axial direction in the outer cylinder, and a sheet-like therapeutic substance. It is supported and provided at the tip of the slide member, and in a free state protruding from the tip of the outer cylinder, it is maintained in a flat developed shape and moves inward of the outer cylinder according to the sliding movement of the slide member And a sheet support member that is accommodated in the outer cylinder while deforming into a cylindrical shape while abutting on the tip of the outer cylinder, and inside the outer cylinder that supports the sheet support in the outer cylinder By forming the partition wall portion that increases the surface area of the sheet, it is possible to accommodate a wider sheet support member.

シート支持部材とスライド部材の間に介在する接続部材を備え、シート支持部材は、外筒から突出される展開状態において、該外筒の軸線と略平行な平面形状に展開されるように接続部材に支持させることができる。あるいは、外筒から突出される展開状態で、該外筒の軸線に対して傾斜した平面形状となるようにシート支持部材を接続部材に支持させてもよい。 A connection member provided between the sheet support member and the slide member, and the sheet support member is deployed in a planar shape substantially parallel to the axis of the outer cylinder in a deployed state protruding from the outer cylinder. Can be supported. Or you may make a connection member support a sheet | seat support member so that it may become a planar shape inclined with respect to the axis line of this outer cylinder in the expansion | deployment state protruded from an outer cylinder.

シート支持部材が外筒の内周長よりも幅広で、筒状の収納形状にするときにその一部が重なる場合には、展開状態におけるシート支持部材の形状を、外筒の軸線と平行でスライド部材との接続部を通る中心線に関して非対称の形状にすることで、重なり部分の干渉を防いでスムーズに収納させることができる。具体的には、シート支持部材は、スライド部材に接続する基端部側の一部領域を非対称な形状にしてもよいし、スライド部材に接続する基端部側から先端部に至る全体を非対称な形状にしてもよい。 If the sheet support member is wider than the inner peripheral length of the outer cylinder and part of it overlaps when it is in the cylindrical storage shape, the shape of the sheet support member in the deployed state should be parallel to the axis of the outer cylinder. By making the shape asymmetric with respect to the center line passing through the connecting portion with the slide member, it is possible to prevent the overlapping portion from interfering and smoothly store it. Specifically, the seat support member may have an asymmetric shape in a partial region on the base end side connected to the slide member, or the whole from the base end side connected to the slide member to the front end portion is asymmetric. Any shape may be used.

上の本発明の治療用物質の運搬投与器具によれば、シート支持部材を筒状にして外筒内に格納することにより、人体に対する侵襲の度合いを低くして、移植部位までシート状の治療用物質を運搬することができる。そして、移植部位に達したときにスライド部材を突出方向に押し出すだけでシート支持部材がその形状維持性によって平面状の展開形状に復元されるので、鉗子などを用いた従来の手法に比べて、極めて容易かつ確実にシート状治療用物質の移植作業を行うことができる。この本発明の運搬投与器具は、外筒内でのスライド部材の進退移動に応じて柔軟性を持つシート支持体が展開状態と筒状の収納状態とに変形されるという簡単な構造であるため、動作不良などの不具合が生じるおそれが少なく、製造コストも低く抑えることができる。 According to the therapeutic substance delivery administration device of the present invention above, the sheet support member is formed into a cylindrical shape and stored in the outer cylinder, thereby reducing the degree of invasion to the human body and performing the sheet-shaped treatment up to the transplantation site. Can transport materials. And, since the sheet support member is restored to a flat deployed shape by its shape maintaining property by simply pushing the slide member in the protruding direction when reaching the transplant site, compared to the conventional method using forceps, The transplantation of the sheet-like therapeutic substance can be performed very easily and reliably. This transport administration device of the present invention has a simple structure in which a flexible sheet support is deformed into an expanded state and a cylindrical storage state in accordance with the forward and backward movement of the slide member in the outer cylinder. Therefore, there is little risk of malfunctions such as malfunctions, and manufacturing costs can be kept low.

図１ないし図４に全体構造を示す本実施形態の運搬投与器具１０は、中空円筒状の外筒１１と、該外筒１１内に摺動可能に支持されたスライド部材１２と、該スライド部材１２の先端部に設けられたシート支持体（シート支持部材）１３を備えている。以下の説明における「軸線方向」及び「径方向」とは、外筒１１の軸線方向（長手方向）と径方向を意味する。外筒１１の一端部には軸線方向に離間する一対の指掛けフランジ１４ａを有するグリップ部１４が設けられており、スライド部材１２には、このグリップ部１４側から突出する側の端部にリング状の指掛け部１５が設けられている。外筒１１に対してスライド部材１２を摺動させるときは、一対の指掛けフランジ１４ａの間に人差し指と中指を挟み、指掛け部１５に親指を挿入し、親指の動作によってスライド部材１２を動かすようにすると操作性がよい。外筒１１の他端部は、外筒１１の軸線と直交する平面Ｐ（図８に一点鎖線で示す）に対して傾斜された傾斜端面１１ａになっている。この平面Ｐに対する傾斜端面１１ａの傾き角は、約３０度となっている。傾斜端面１１ａには面取り加工がなされていて、滑らかな先端形状になっている。 A transport administration device 10 of the present embodiment whose entire structure is shown in FIGS. 1 to 4 includes a hollow cylindrical outer cylinder 11, a slide member 12 slidably supported in the outer cylinder 11, and the slide member. 12 is provided with a sheet support (sheet support member) 13 provided at the front end portion. In the following description, “axial direction” and “radial direction” mean an axial direction (longitudinal direction) and a radial direction of the outer cylinder 11. A grip portion 14 having a pair of finger-hanging flanges 14a spaced apart in the axial direction is provided at one end portion of the outer cylinder 11, and the slide member 12 has a ring shape at the end portion protruding from the grip portion 14 side. Is provided. When sliding the slide member 12 with respect to the outer cylinder 11, the index finger and the middle finger are sandwiched between the pair of finger-hanging flanges 14a, the thumb is inserted into the finger-hanging portion 15, and the slide member 12 is moved by the operation of the thumb. The operability is good. The other end portion of the outer cylinder 11 is an inclined end surface 11 a that is inclined with respect to a plane P (indicated by a one-dot chain line in FIG. 8) orthogonal to the axis of the outer cylinder 11. The inclination angle of the inclined end surface 11a with respect to the plane P is about 30 degrees. The inclined end surface 11a is chamfered and has a smooth tip shape.

図６に示すように、外筒１１の内周面とスライド部材１２との間にはＯリング１６が設けられている。Ｏリング１６は、運搬投与器具１０の使用中に外筒１１内を通って体内から外部空間に抜けようとする空気漏れを防ぐ機能と、スライド部材１２の摺動動作に適度な抵抗を与える機能と、外筒１１に対するスライド部材１２の倒れを防ぐ（同心性を維持させる）機能とを有する。図６では一箇所のみのＯリング１６を示しているが、外筒１１の軸線方向に位置を異ならせて複数のＯリングを設けてもよい。また、Ｏリング１６と同様のＯリングを、後述する接続部材１７の外周面と外筒１１の内周面との間に設けてもよい。 As shown in FIG. 6, an O-ring 16 is provided between the inner peripheral surface of the outer cylinder 11 and the slide member 12. The O-ring 16 has a function of preventing air leakage from passing through the outer cylinder 11 to the outside space during use of the delivery device 10 and a function of giving appropriate resistance to the sliding operation of the slide member 12. And a function of preventing the slide member 12 from falling over the outer cylinder 11 (maintaining concentricity). Although only one O-ring 16 is shown in FIG. 6, a plurality of O-rings may be provided at different positions in the axial direction of the outer cylinder 11. Further, an O-ring similar to the O-ring 16 may be provided between the outer peripheral surface of the connecting member 17 described later and the inner peripheral surface of the outer cylinder 11.

シート支持体１３は、柔軟性を有する薄板状体であり、図１、図７及び図１１に示すシート状の治療用物質３０（以下、シート３０と呼ぶ）を支持するシート支持面部１３ａと、該シート支持面部１３ａの基端部に位置する接続部１３ｂと、シート支持面部１３ａから接続部１３ｂに向けて徐々に幅を狭くしていく幅徐変部１３ｃとを有している。幅徐変部１３ｃは、外筒１１の軸線を挟んで略対称な形状をなす一対の側縁部を有し、それぞれの側縁部は、シート支持面部１３ａに連続する凸状の円弧部（Ｒ面）と、接続部１３ｂに続く凹状の円弧部（Ｒ面）を組み合わせて構成されている。シート支持体１３は、外力を加えない自由状態では、図７や図１１に示すように、シート支持面部１３ａが平面状に展開された形状に維持される。 The sheet support 13 is a flexible thin plate-like body, and a sheet support surface portion 13a that supports the sheet-like therapeutic substance 30 (hereinafter referred to as the sheet 30) shown in FIGS. 1, 7, and 11; It has a connecting portion 13b located at the base end portion of the sheet supporting surface portion 13a and a width gradually changing portion 13c that gradually decreases in width from the sheet supporting surface portion 13a toward the connecting portion 13b. The width gradually changing portion 13c has a pair of side edge portions that are substantially symmetrical with respect to the axis of the outer cylinder 11, and each side edge portion is a convex arc portion (continuous to the sheet supporting surface portion 13a). (R surface) and a concave arc portion (R surface) following the connecting portion 13b. In a free state in which no external force is applied, the sheet support 13 is maintained in a shape in which the sheet support surface portion 13a is flattened as shown in FIGS.

シート支持体１３とスライド部材１２は接続部材１７を介して接続される。図８ないし図１０に示すように、接続部材１７は、先端部側から順に、２つのねじ孔１７ａ、差し込み溝１７ｂ、嵌合段部１７ｃを有し、嵌合段部１７ｃ上には離間移動規制突起１７ｄが形成されている。ねじ孔１７ａの形成領域には、外筒１１の軸線と略平行をなす支持平面１７ｅが形成されている。シート支持体１３の接続部１３ｂには、接続部材１７の２つのねじ孔１７ａに重なる位置関係で２つの貫通孔１３ｄが形成され、接続部１３ｂの末端部には差し込み溝１７ｂに係合可能な終端曲げ部１３ｅが折り曲げ形成されている。終端曲げ部１３ｅを差し込み溝１７ｂに係合させて接続部１３ｂを支持平面１７ｅ上に載せると、２つの貫通孔１３ｄが２つのねじ孔１７ａと重なって位置される。ここで各貫通孔１３ｄを通して各ねじ孔１７ａに固定ねじ２０を螺合させることにより、シート支持体１３と接続部材１７が固定される。または、固定ねじ２０の代わりにピンを圧入することでシート支持体１３と接続部材１７を固定してもよい。 The sheet support 13 and the slide member 12 are connected via a connection member 17. As shown in FIGS. 8 to 10, the connecting member 17 has two screw holes 17 a, an insertion groove 17 b, and a fitting step portion 17 c in order from the tip end side, and moves apart on the fitting step portion 17 c. A restricting projection 17d is formed. A support plane 17e that is substantially parallel to the axis of the outer cylinder 11 is formed in the formation region of the screw hole 17a. Two through holes 13d are formed in the connection portion 13b of the sheet support 13 so as to overlap the two screw holes 17a of the connection member 17, and the end portion of the connection portion 13b can be engaged with the insertion groove 17b. A terminal bent portion 13e is formed by bending. When the terminal bending portion 13e is engaged with the insertion groove 17b and the connection portion 13b is placed on the support plane 17e, the two through holes 13d are positioned so as to overlap the two screw holes 17a. Here, the seat support 13 and the connecting member 17 are fixed by screwing the fixing screws 20 into the screw holes 17a through the through holes 13d. Alternatively, the sheet support 13 and the connection member 17 may be fixed by press-fitting a pin instead of the fixing screw 20.

スライド部材１２の先端は、接続部材１７の嵌合段部１７ｃに嵌合する嵌合段部１２ａとなっており、この嵌合段部１２ａに、離間移動規制突起１７ｄが嵌合する形状の離間移動規制凹部１２ｂ（図８に断面のみ示す）が形成されている。接続部材１７に設けた離間移動規制突起１７ｄは、図９に示すように、スライド部材１２の先端側から基端側（指掛け部１５側）に向かうにつれて徐々に幅を大きくする台形状の突起である。そのため、軸線方向において離間する方向へのスライド部材１２と接続部材１７の相対移動は、離間移動規制凹部１２ｂと離間移動規制突起１７ｄの嵌合関係によって規制される。一方、嵌合段部１２ａと嵌合段部１７ｃは、互いの端面の当接関係によって、軸線方向において互いに接近する方向へのスライド部材１２と接続部材１７の相対移動を規制する。すなわち、スライド部材１２と接続部材１７は、軸線方向の正逆いずれの方向にも相対移動しないように連結される。この連結構造は、径方向への相対移動によって解除可能である。 The front end of the slide member 12 is a fitting step portion 12a that fits into the fitting step portion 17c of the connection member 17, and the fitting step portion 12a is spaced with a shape in which the separation movement restricting projection 17d is fitted. A movement restricting recess 12b (only a cross section is shown in FIG. 8) is formed. As shown in FIG. 9, the separation movement restricting protrusion 17 d provided on the connection member 17 is a trapezoidal protrusion that gradually increases in width from the distal end side of the slide member 12 toward the proximal end side (finger holding portion 15 side). is there. Therefore, the relative movement of the slide member 12 and the connection member 17 in the direction away from each other in the axial direction is restricted by the fitting relationship between the separation movement restriction recess 12b and the separation movement restriction protrusion 17d. On the other hand, the fitting step portion 12a and the fitting step portion 17c regulate relative movement of the slide member 12 and the connection member 17 in a direction approaching each other in the axial direction by the contact relationship between the end faces. That is, the slide member 12 and the connection member 17 are coupled so as not to move relative to either the forward or reverse axial direction. This connection structure can be released by a relative movement in the radial direction.

図６に示すように、外筒１１とグリップ部１４は、互いを連通するねじ孔を有し、このねじ孔に対してスライド制御ねじ２２を螺合させることで一体化される。スライド制御ねじ２２は、外筒１１とグリップ部１４を固定する機能に加えて、スライド部材１２の軸線方向移動量を制御する移動制限手段としても機能する。 As shown in FIG. 6, the outer cylinder 11 and the grip portion 14 have screw holes that communicate with each other, and are integrated by screwing a slide control screw 22 into the screw holes. In addition to the function of fixing the outer cylinder 11 and the grip portion 14, the slide control screw 22 also functions as a movement limiting unit that controls the amount of movement of the slide member 12 in the axial direction.

スライド制御ねじ２２の先端部は、外筒１１の内周面から突出してスライド部材１２の外周面に形成した規制溝（移動制限手段）１２ｃに係合している。図５に示すように、規制溝１２ｃは、外筒１１の軸線方向に長い第１の直線溝部分１２ｃ-１と、該第１の直線溝部分１２ｃ-１に一端部が連通する周方向溝部分１２ｃ-２と、該周方向溝部分１２ｃ-２の他端部から指掛け部１５方向へ向けて外筒１１の軸線方向へ向けて形成された第２の直線溝部分１２ｃ-３とを有するクランク形状の溝部となっている。図６は、規制溝１２ｃの第１の直線溝部分１２ｃ-１の終端部、すなわち周方向溝部分１２ｃ-２にスライド制御ねじ２２が当て付いた状態を示しており、通常の使用状態では、これよりも外筒１１の先端部方向へのスライド部材１２の軸線方向移動が規制される。このスライド規制状態においては、スライド部材１２と接続部材１７の連結部分は、図７及び図８に示すように外筒１１の内周面によって囲まれる位置にある。前述したように、接続部材１７はスライド部材１２に対して、外筒１１の軸線方向（図８の左右方向）には相対移動が規制され、外筒１１の径方向（図８の上下方向）にのみ分解可能であるが、図８の状態では、この径方向への接続部材１７とスライド部材１２の相対移動は外筒１１の内周面によって規制される。すなわち、スライド制御ねじ２２が規制溝１２ｃの第１の直線溝部分１２ｃ-１に位置する通常の使用状態では、スライド部材１２と接続部材１７が分解可能状態になることがない。 The distal end portion of the slide control screw 22 is engaged with a regulation groove (movement restriction means) 12 c that protrudes from the inner circumferential surface of the outer cylinder 11 and is formed on the outer circumferential surface of the slide member 12. As shown in FIG. 5, the regulation groove 12 c includes a first linear groove portion 12 c-1 that is long in the axial direction of the outer cylinder 11, and a circumferential groove whose one end communicates with the first linear groove portion 12 c-1. A portion 12c-2 and a second linear groove portion 12c-3 formed in the axial direction of the outer cylinder 11 from the other end portion of the circumferential groove portion 12c-2 toward the finger hooking portion 15; It is a crank-shaped groove. FIG. 6 shows a state in which the slide control screw 22 is abutted against the terminal end portion of the first linear groove portion 12c-1 of the restricting groove 12c, that is, the circumferential groove portion 12c-2. The axial movement of the slide member 12 in the direction toward the distal end portion of the outer cylinder 11 is further restricted. In this slide regulation state, the connecting portion of the slide member 12 and the connection member 17 is at a position surrounded by the inner peripheral surface of the outer cylinder 11 as shown in FIGS. As described above, relative movement of the connecting member 17 with respect to the slide member 12 is restricted in the axial direction of the outer cylinder 11 (left-right direction in FIG. 8), and the radial direction of the outer cylinder 11 (up-down direction in FIG. 8). However, in the state of FIG. 8, the relative movement of the connecting member 17 and the slide member 12 in the radial direction is restricted by the inner peripheral surface of the outer cylinder 11. That is, in the normal use state where the slide control screw 22 is positioned in the first linear groove portion 12c-1 of the restriction groove 12c, the slide member 12 and the connecting member 17 are not disassembled.

図６のようにスライド制御ねじ２２が規制溝１２ｃの第１の直線溝部分１２ｃ-１の終端部（周方向溝部分１２ｃ-２）に当接した状態から外筒１１とスライド部材１２を相対回転させ、規制溝１２ｃにおける第２の直線溝部分１２ｃ-３とスライド制御ねじ２２の周方向位相が一致した状態にすると、図６ないし図８の位置よりもさらに突出方向へスライド部材１２をスライドさせることが可能になる。すると外筒１１による規制が解除されて、図９に示すように接続部材１７をスライド部材１２から取り外すことが可能になる。さらにスライド制御ねじ２２を取り外せば、外筒１１、スライド部材１２及びグリップ部１４を分解することも可能である。 As shown in FIG. 6, the outer cylinder 11 and the slide member 12 are moved relative to each other from the state in which the slide control screw 22 is in contact with the terminal end portion (circumferential groove portion 12c-2) of the first linear groove portion 12c-1 of the restriction groove 12c. If the second linear groove portion 12c-3 in the restricting groove 12c and the circumferential phase of the slide control screw 22 coincide with each other, the slide member 12 is slid further in the projecting direction than the positions in FIGS. It becomes possible to make it. Then, the restriction by the outer cylinder 11 is released, and the connection member 17 can be detached from the slide member 12 as shown in FIG. Further, if the slide control screw 22 is removed, the outer cylinder 11, the slide member 12, and the grip portion 14 can be disassembled.

なお、図６に示すスライド制御ねじ２２は、軸部の全体にねじが形成されているものであるが、例えばスライド部材規制溝１２ｃに係合する先端部分にはねじが形成されていない態様にすることもできる。このようにスライド案内用の摺動部分を平滑面とすることにより、スライド部材１２が摺動するときの円滑性を向上させることができる。 In addition, although the slide control screw 22 shown in FIG. 6 is a screw formed in the whole axial part, the screw is not formed in the front-end | tip part engaged with the slide member control groove | channel 12c, for example. You can also Thus, the smoothness when the slide member 12 slides can be improved by making the sliding part for slide guidance into a smooth surface.

図１１は、前述した規制溝１２ｃ（第１の直線溝部分１２ｃ-１）とスライド制御ねじ２２の関係による通常使用状態の最大突出位置（前方移動端）までスライド部材１２を押し出した状態を示しており、この状態でシート支持体１３は外筒１１の先端から突出されて、その形状維持性によりシート支持面部１３ａを平面状に展開させている。展開された状態のシート支持体１３は、外筒１１の内径サイズよりも広い幅を有している。図１１の状態から矢印Ｓ１で示す引き込み方向へスライド部材１２をスライドさせると、図１２に示すようにシート支持体１３の幅徐変部１３ｃが外筒１１の傾斜端面１１ａに接触する。すると、傾斜端面１１ａと幅徐変部１３ｃのそれぞれの傾斜形状によって、スライド部材１２の軸線方向移動力からシート支持体１３を筒状に丸めようとする分力Ｆ（図１２）が生じる。このとき筒状になろうとするシート支持体１３の内側の面が、シート３０を支持する支持面となる。具体的には、図１１や図１２に見えているのがシート３０の支持面であり、図１、図３及び図７で見えているのは、この支持面とは反対側の裏面である。図４や図８では、シート支持体１３のうち図中下側の面がシート３０の支持面、図中上側の面がその裏面である。 FIG. 11 shows a state in which the slide member 12 is pushed out to the maximum protruding position (forward movement end) in the normal use state due to the relationship between the restriction groove 12c (first linear groove portion 12c-1) and the slide control screw 22 described above. In this state, the sheet support 13 is projected from the tip of the outer cylinder 11, and the sheet support surface portion 13a is developed in a flat shape due to its shape maintenance. The unfolded sheet support 13 has a width wider than the inner diameter size of the outer cylinder 11. When the slide member 12 is slid in the pull-in direction indicated by the arrow S1 from the state shown in FIG. 11, the width gradually changing portion 13c of the sheet support 13 contacts the inclined end surface 11a of the outer cylinder 11 as shown in FIG. Then, due to the respective inclined shapes of the inclined end surface 11a and the width gradually changing portion 13c, a component force F (FIG. 12) is generated that tries to round the sheet support 13 into a cylindrical shape from the moving force in the axial direction of the slide member 12. At this time, the inner surface of the sheet support 13 which is going to be cylindrical becomes a support surface for supporting the sheet 30. Specifically, what is visible in FIGS. 11 and 12 is the support surface of the sheet 30, and what is visible in FIGS. 1, 3, and 7 is the back surface opposite to the support surface. . 4 and 8, the lower surface in the figure of the sheet support 13 is the support surface of the sheet 30, and the upper surface in the figure is the back surface thereof.

図１２の状態からスライド部材１２の引き込み動作を継続すると、図１３、図１４に順を追って示すように、スライド部材１２の移動に応じてシート支持体１３は、外筒１１の内周面形状に沿う円筒形状に丸められながら外筒１１内に収納されていく。図１３の段階ではまだ幅徐変部１３ｃが傾斜端面１１ａに当接しており、スライド部材１２の軸線方向移動力に応じてシート支持体１３を筒状に丸めようとする分力が作用している。図１４の段階まで至ると幅徐変部１３ｃは外筒１１内に収納された状態になるが、このとき外筒１１の先端部（傾斜端面１１ａの開口部）においては、シート支持面部１３ａの両側部が互いに隣接した状態まで接近されて、シート支持体１３は概ね筒状形状への変形が完了している、よって、図１４の状態からスライド部材１２を引き込み方向へスライドさせても、シート支持体１３は、傾斜端面１１ａとの間で引っ掛かりを生じることなく、シート支持面部１３ａの先端部側に向けて徐々に円筒状に丸まりながら外筒１１内に収納されていく。なお、外筒１１の傾斜端面１１ａには鋭利な部分をなくす面取り加工がなされているので、以上の収納動作時に傾斜端面１１ａとの当接によってシート支持体１３が破損するおそれはない。 When the retracting operation of the slide member 12 is continued from the state of FIG. 12, the sheet support 13 changes the shape of the inner peripheral surface of the outer cylinder 11 according to the movement of the slide member 12 as shown in order in FIGS. 13 and 14. And is housed in the outer cylinder 11 while being rounded into a cylindrical shape. In the stage of FIG. 13, the width gradually changing portion 13 c is still in contact with the inclined end surface 11 a, and a component force is applied to round the sheet support 13 into a cylindrical shape according to the axial movement force of the slide member 12. Yes. When the stage of FIG. 14 is reached, the width gradually changing portion 13c is housed in the outer cylinder 11. At this time, at the front end portion of the outer cylinder 11 (opening portion of the inclined end surface 11a), the sheet supporting surface portion 13a The two side portions are brought close to each other, and the sheet support 13 has been substantially deformed into a cylindrical shape. Therefore, even if the slide member 12 is slid in the retracting direction from the state shown in FIG. The support body 13 is housed in the outer cylinder 11 while being gradually rounded into a cylindrical shape toward the tip end side of the sheet support surface portion 13a without being caught between the support body 13 and the inclined end surface 11a. Since the inclined end surface 11a of the outer cylinder 11 is chamfered to eliminate a sharp portion, there is no possibility that the sheet support 13 is damaged due to contact with the inclined end surface 11a during the above storage operation.

図１５はシート支持体１３の全体が外筒１１内に収納された状態であり、シート支持体１３は外筒１１の内周面に沿う筒状形状に変形されている。シート支持体１３は、この筒状の収納状態において、自身の一部が重なることがないように幅寸法が定められている。具体的には、外筒１１の内径サイズが９．５ｍｍである場合、シート支持体１３の横幅サイズが２８ｍｍ程度であると、重なりを生じることなく外筒１１の内周面に沿って筒状に収納することができる。 FIG. 15 shows a state in which the entire sheet support 13 is housed in the outer cylinder 11, and the sheet support 13 is deformed into a cylindrical shape along the inner peripheral surface of the outer cylinder 11. The width of the sheet support 13 is determined so that parts of the sheet support 13 do not overlap in this cylindrical storage state. Specifically, when the inner cylinder 11 has an inner diameter of 9.5 mm, and the lateral width of the sheet support 13 is about 28 mm, the outer cylinder 11 has a cylindrical shape along the inner peripheral surface without overlapping. Can be stored.

以上の収納時とは逆に、図１５の収納状態からスライド部材１２を矢印Ｓ２で示す突出方向へスライドさせると、シート支持体１３はその形状復元性によって、外筒１１から突出する部分を徐々に平面方向に拡げていき、図１４の状態、図１３の状態、図１２の状態と変形していく。そして、図１１の最大突出位置までスライド部材１２を移動させると、幅徐変部１３ｃが傾斜端面１１ａから離れて外筒１１によるシート支持体１３への形状規制が解除され、自由状態となったシート支持面部１３ａが平面状に展開される。 Contrary to the above storage, when the slide member 12 is slid in the protruding direction indicated by the arrow S2 from the storage state of FIG. 15, the sheet support 13 gradually moves the portion protruding from the outer cylinder 11 due to its shape recoverability. It expands in the plane direction and deforms to the state of FIG. 14, the state of FIG. 13, and the state of FIG. Then, when the slide member 12 is moved to the maximum projecting position in FIG. 11, the width gradually changing portion 13c is separated from the inclined end surface 11a, the shape restriction on the sheet support 13 by the outer cylinder 11 is released, and the free state is entered. The sheet support surface portion 13a is developed in a planar shape.

図４に示すように、外筒１１の径方向におけるシート支持体１３の位置は、筒状形状への湾曲変形の方向（図４における下方）と反対方向にできるだけ偏心させることが好ましい。すなわち、シート支持体１３が図４の位置よりも下方、例えば外筒１１の中心軸位置よりも下方に位置していると、シート支持体１３が筒状に湾曲変形されながら外筒１１内に収納されようとする際に、外筒１１との間に引っ掛かりが生じて途中までしか収納できなくなるおそれがある。あるいは、外筒１１に収納可能なシート支持体１３の幅が狭くなってしまう。これに対し、図４のように、湾曲方向と反対側の外筒１１の径方向内縁部（図４の上方）に近づけてシート支持体１３を位置させることにより、干渉を生じることなくスムーズにシート支持体１３を外筒１１内に収納することができ、また外筒１１内に収納できるシート支持体１３の幅も大きくすることができる。 As shown in FIG. 4, the position of the sheet support 13 in the radial direction of the outer cylinder 11 is preferably decentered as much as possible in the direction opposite to the direction of bending deformation into the cylindrical shape (downward in FIG. 4). That is, when the sheet support 13 is positioned below the position of FIG. 4, for example, below the center axis position of the outer cylinder 11, the sheet support 13 is curved and deformed into a cylindrical shape in the outer cylinder 11. When it is going to be stored, there is a possibility that it will be caught between the outer cylinder 11 and can only be stored halfway. Or the width | variety of the sheet | seat support body 13 which can be accommodated in the outer cylinder 11 will become narrow. On the other hand, as shown in FIG. 4, the sheet support 13 is positioned close to the radially inner edge (upward in FIG. 4) of the outer cylinder 11 on the side opposite to the bending direction, thereby smoothly causing no interference. The sheet support 13 can be stored in the outer cylinder 11, and the width of the sheet support 13 that can be stored in the outer cylinder 11 can be increased.

以上のようにシート支持体１３は、スライド部材１２の進退移動に応じて平面状の展開形状と筒状形状に変形されるものであり、外筒１１から突出されたときに平面状に展開される形状維持（復元）性を備えている。例えば、ポリプロピレン、アクリル樹脂、ポリエチレンテレフタラート、ポリエチレンといった材質からなる適当な厚さの樹脂フィルムによって、上記のような形状維持性を有するシート支持体１３を得ることができる。あるいは、シリコンゴムや、超弾性合金、形状記憶合金などの金属製の薄板によってシート支持体１３を形成することもできる。また、シート支持体１３の形状は、図示のような薄板状体に代えて網状体（金網状体）として構成することも可能である。シート支持体１３の柔軟性（硬度）は、その材質や厚さを変化させることによって任意に設定することができるが、一例として、上記のような樹脂フィルムでシート支持体１３を形成する場合、厚さは５０〜５００μｍ程度にすることが好ましい。 As described above, the sheet support 13 is deformed into a flat developed shape and a cylindrical shape in accordance with the forward / backward movement of the slide member 12, and is developed into a flat shape when projected from the outer cylinder 11. It has a shape maintenance (restoration) property. For example, the sheet support 13 having the shape maintaining property as described above can be obtained by using a resin film having an appropriate thickness made of a material such as polypropylene, acrylic resin, polyethylene terephthalate, or polyethylene. Alternatively, the sheet support 13 can be formed of a thin metal plate such as silicon rubber, a superelastic alloy, or a shape memory alloy. Further, the shape of the sheet support 13 can be configured as a net (metal mesh) instead of a thin plate as shown. The flexibility (hardness) of the sheet support 13 can be arbitrarily set by changing its material and thickness, but as an example, when the sheet support 13 is formed of the resin film as described above, The thickness is preferably about 50 to 500 μm.

また、シート支持体１３のシート支持面部１３ａには、シート３０を安定して保持するための表面処理が施される。表面処理は様々な態様が可能であり、例えば、シート３０と摩擦係合する表面材料をシート支持面部１３ａの表面にコーティングしたり、シート支持面部１３ａ上に比較的弱い接着力の接着層を設けたりするとよい。特にシート３０が繊維性の治療物質である場合には、シート支持面部１３ａに繊維層を貼り付けておくことが有用である。シート支持面部１３ａ側の繊維とシート３０側の繊維が絡み合うことで、運搬時の脱落のおそれがない程度の強さでシート３０を仮固定することができ、しかも移植時には破損を生じることなく簡単にシート３０をシート支持面部１３ａ上から離脱させることができる。あるいは、シート支持面部１３ａの一部に切れ目を形成し、運搬時にシート３０の一部を物理的に挟んで脱落を防ぐことも可能である。いずれの態様にせよ、運搬時にはシート支持体１３から不用意にシート３０が脱落することがなく、移植時にはシート３０をシート支持面部１３ａから離脱させて患部側へ確実に移植させられる適度な保持力を有するように設定される。なお、移植時にシート支持面部１３ａからシート３０を離脱させやすくするための構成として、例えば、シート支持面部１３ａに微細な孔を形成しておき、この孔から生理食塩水などを浸透させてシート支持面部１３ａとシート３０との間に液体の層を作ってシート３０を剥がし易くするような構成を採用してもよい。 Further, the sheet support surface portion 13a of the sheet support 13 is subjected to a surface treatment for stably holding the sheet 30. The surface treatment can take various forms. For example, a surface material that frictionally engages with the sheet 30 is coated on the surface of the sheet support surface portion 13a, or an adhesive layer having a relatively weak adhesive force is provided on the sheet support surface portion 13a. Or better. In particular, when the sheet 30 is a fibrous therapeutic substance, it is useful to attach a fiber layer to the sheet support surface portion 13a. Since the fibers on the sheet support surface portion 13a side and the fibers on the sheet 30 side are entangled, the sheet 30 can be temporarily fixed with such a strength that there is no fear of dropping during transportation, and it is easy without causing damage during transplantation. In addition, the sheet 30 can be detached from the sheet support surface portion 13a. Alternatively, it is also possible to form a cut in a part of the sheet support surface portion 13a and prevent the dropout by physically sandwiching a part of the sheet 30 during transportation. In any manner, the sheet 30 is not inadvertently dropped from the sheet support 13 at the time of transportation, and at the time of transplantation, the sheet 30 can be detached from the sheet support surface portion 13a and reliably transplanted to the affected part side. Is set to have. As a configuration for facilitating separation of the sheet 30 from the sheet support surface portion 13a at the time of transplantation, for example, a fine hole is formed in the sheet support surface portion 13a, and physiological saline or the like is permeated through the hole to support the sheet. A configuration may be adopted in which a liquid layer is formed between the surface portion 13a and the sheet 30 so that the sheet 30 can be easily peeled off.

また、使用時の利便性を考慮した場合、シート支持体１３は透明もしくは半透明であることが好ましい。透明であると、シート支持面部１３ａ上に支持されたシート３０の状態を裏面側からでも観察することができる。また、シート移植作業中において、シート支持体１３を通して患部の位置を視認してシート３０の位置合わせを容易に行うことができる。 In consideration of convenience during use, the sheet support 13 is preferably transparent or translucent. If it is transparent, the state of the sheet 30 supported on the sheet support surface portion 13a can be observed even from the back side. Further, during the sheet transplanting operation, the position of the affected part can be visually recognized through the sheet support 13 and the sheet 30 can be easily aligned.

また、シート支持体１３には、シート３０に対する保持機能や色の設定とは別に、用途に応じた様々な機能を付加することができる。例えば、外筒１１に摺接する部分の潤滑性を高めるコーティングを施したり、材質やコーティングの選択によって表面の撥水性に変化を持たせたりすることができる。また、本実施形態のシート支持体１３におけるシート支持面部１３ａは、展開状態で略矩形をなしているが、シート支持面部の形状は矩形に限られるものではなく、用途や支持するシートの形に応じて任意の形状にすることができる。 In addition to the holding function for the sheet 30 and the color setting, the sheet support 13 can be provided with various functions depending on the application. For example, a coating that improves the lubricity of the portion in sliding contact with the outer cylinder 11 can be applied, or the water repellency of the surface can be changed depending on the choice of material and coating. In addition, the sheet support surface portion 13a of the sheet support body 13 of the present embodiment is substantially rectangular in the unfolded state, but the shape of the sheet support surface portion is not limited to a rectangle, and the shape of the sheet to be supported and supported Depending on the shape, any shape can be obtained.

以上の構造からなる運搬投与器具１０は次のように用いられる。本実施形態の運搬投与器具１０では、シート支持体１３と接続部材１７の結合体が、スライド部材１２に対する脱着可能な脱着部を構成しており、この脱着部は、使用毎に新しいものに交換される。これに対し、外筒１１やスライド部材１２からなる本体部は、繰り返しの使用に耐えうる強度、構造をもち滅菌処理に対応する材質（ステンレスなど）で形成し、使用後に滅菌処理を行って再使用してもよい。これにより、使い捨て部分を少なくして環境対策を図ると共に運用コストを下げることが可能となる。 The delivery device 10 having the above structure is used as follows. In the transport administration device 10 of the present embodiment, the combination of the sheet support 13 and the connection member 17 constitutes a detachable part that can be detached from the slide member 12, and this detachable part is replaced with a new one every time it is used. Is done. On the other hand, the main body portion including the outer cylinder 11 and the slide member 12 is formed of a material (stainless steel or the like) having a strength and a structure that can withstand repeated use, and is sterilized after use, and then re-used. May be used. As a result, it is possible to reduce the operating cost while reducing the number of disposable parts and taking environmental measures.

シート支持体１３を有する脱着部は、シート支持面部１３ａ上にシート３０が載せられた状態で滅菌パックされており、使用時にはパッケージから取り出して、接続部材１７を介してスライド部材１２の先端部に取り付けられる。この取り付け時には、スライド部材１２は前述した通常使用状態の最大突出位置よりも突出された分解用位置に保持させておく。このときスライド制御ねじ２２は、規制溝１２ｃのうちの分解用領域である第２の直線溝部分１２ｃ-３内に位置している。脱着部の取り付けが完了したら、スライド部材１２を引き込み方向へスライドさせる。すると、スライド制御ねじ２２が規制溝１２ｃの周方向溝部分１２ｃ-２に当て付くので、スライド部材１２を所定角度回転させて、スライド制御ねじ２２の回転位相を、規制溝１２ｃのうちの通常使用領域である第１の直線溝部分１２ｃ-１と一致させる。この状態が図１、図３、図４、図７及び図１１に示す状態である。さらにスライド部材１２を引き込み方向にスライドさせると、幅徐変部１３ｃが外筒１１の傾斜端面１１ａに当接し、前述した要領で、シート支持体１３が筒状に丸められながら外筒１１内に収納されていく（図１２から図１５）。このとき、シート３０は筒状に閉じられるシート支持面部１３ａの内側の面に支持されているため、外筒１１の内壁に対するシート３０の接触や擦れが生じず、シート３０の損傷を防ぐことができる。そして、図２に示すようにシート支持体１３が外筒１１内に完全に収納されると、シート３０が外筒１１によって保護された状態となる。シート支持体１３は外筒１１内で二重に重ならないように収納されているため、該シート支持体１３上に支持されたシート３０も、擦れによる損傷を生じることなく安定した形状で保持される。 The detachable part having the sheet support 13 is sterilized and packed with the sheet 30 placed on the sheet support surface part 13a, and is taken out from the package and used at the tip of the slide member 12 via the connecting member 17 in use. It is attached. At the time of attachment, the slide member 12 is held at the disassembling position that protrudes from the maximum protruding position in the normal use state described above. At this time, the slide control screw 22 is located in the second linear groove portion 12c-3 which is a disassembling region in the restriction groove 12c. When the attachment of the detachable part is completed, the slide member 12 is slid in the pull-in direction. Then, since the slide control screw 22 abuts on the circumferential groove portion 12c-2 of the restriction groove 12c, the slide member 12 is rotated by a predetermined angle, and the rotation phase of the slide control screw 22 is set to the normal use of the restriction groove 12c. It is made to correspond with the 1st linear groove part 12c-1 which is an area | region. This state is the state shown in FIG. 1, FIG. 3, FIG. 4, FIG. When the slide member 12 is further slid in the pull-in direction, the width gradually changing portion 13c comes into contact with the inclined end surface 11a of the outer cylinder 11, and the sheet support 13 is rolled into a cylindrical shape in the outer cylinder 11 as described above. It is stored (FIGS. 12 to 15). At this time, since the sheet 30 is supported on the inner surface of the sheet support surface portion 13a that is closed in a cylindrical shape, the sheet 30 does not contact or rub against the inner wall of the outer cylinder 11, and the sheet 30 can be prevented from being damaged. it can. As shown in FIG. 2, when the sheet support 13 is completely stored in the outer cylinder 11, the sheet 30 is protected by the outer cylinder 11. Since the sheet support 13 is stored in the outer cylinder 11 so as not to be doubled, the sheet 30 supported on the sheet support 13 is also held in a stable shape without causing damage due to rubbing. The

次に、シート支持体１３が外筒１１内に収納された状態を保ちつつ、運搬投与器具１０を体内に挿入する。より詳しくは、腹腔鏡下手術や胸腔鏡下手術に際して予め体内に挿入されたトラカールを介して外筒１１が挿入される。このとき、外筒１１の先端部が傾斜した傾斜端面１１ａになっているため、挿入作業を行いやすくなっている。外筒１１の先端部が体内におけるシート移植対象部位（患部）の近傍に達したところで、スライド部材１２を突出方向（外筒１１の先端方向）にスライドさせる。すると、前述の要領によって、シート支持体１３が外筒１１の先端から突出して形状が復元され、シート３０を支持したシート支持面部１３ａが図１１のように平面状に展開される。このとき、スライド部材１２を通常使用状態の最大突出位置まで移動させてもシート支持体１３と接続部材１７の結合体はスライド部材１２から外れないので、シート支持体１３や接続部材１７を体内に脱落させてしまうおそれはない。 Next, the transport administration device 10 is inserted into the body while the sheet support 13 is kept in the outer cylinder 11. More specifically, the outer cylinder 11 is inserted through a trocar previously inserted into the body during laparoscopic surgery or thoracoscopic surgery. At this time, since the distal end portion of the outer cylinder 11 is an inclined end surface 11a, it is easy to perform an insertion operation. When the distal end portion of the outer cylinder 11 reaches the vicinity of the site to be transplanted (affected part) in the body, the slide member 12 is slid in the protruding direction (the distal end direction of the outer cylinder 11). Then, according to the above-described procedure, the sheet support 13 protrudes from the distal end of the outer cylinder 11 to restore the shape, and the sheet support surface portion 13a that supports the sheet 30 is developed in a planar shape as shown in FIG. At this time, even if the slide member 12 is moved to the maximum protruding position in the normal use state, the combined body of the sheet support 13 and the connection member 17 does not come off from the slide member 12, so that the sheet support 13 and the connection member 17 are brought into the body. There is no risk of dropping off.

続いて、シート３０が移植対象部位に対向するように運搬投与器具１０の向きを調整し、シート支持体１３のシート支持面部１３ａを移植対象部位に押し付ける。すると、シート３０がシート支持面部１３ａから離れて移植対象部位に移植される。前述したように、シート支持面部１３ａの表面には、運搬時には脱落させず、かつ移植を妨げない程度の保持力でシート３０を保持する表面処理が施されており、シート支持面部１３ａを所定の力で押し付けることにより、シート３０をシート支持面部１３ａから離脱させて移植対象部位へ確実に移植させることができる。また、シート支持体１３は柔軟性を有するので、非平面状の移植対象部位に対しても、ある程度柔軟に変形してシート３０の形状を対応させることができる。 Subsequently, the direction of the delivery device 10 is adjusted so that the sheet 30 faces the transplant target site, and the sheet support surface portion 13a of the sheet support 13 is pressed against the transplant target site. Then, the sheet 30 leaves the sheet support surface portion 13a and is transplanted to the transplant target site. As described above, the surface of the sheet support surface portion 13a is subjected to a surface treatment that holds the sheet 30 with a holding force that does not drop off during transportation and does not hinder transplantation. By pressing with force, the sheet 30 can be detached from the sheet support surface portion 13a and reliably transplanted to the site to be transplanted. Moreover, since the sheet | seat support body 13 has a softness | flexibility, it can deform | transform somewhat flexibly and can respond | correspond to the shape of the sheet | seat 30 also with respect to a non-planar transplant object site | part.

なお、シート３０の移植は、単にシート支持面部１３ａを移植対象部位に押し付けるだけでなく、異なる態様で行ってもよい。その一例として、シート３０の長さを、シート支持体１３に支持させたときシート支持面部１３ａの先端部よりも若干突出するように設定しておく。そして、シート支持体１３を展開してシート３０を移植対象部位に接触させた状態で、シート３０のうちシート支持面部１３ａの先端から突出する部分を鉗子などで押さえつつ、このシート突出部分から離れるように（接続部１３ｂの方向へ向けて）シート支持体１３をシート支持面部１３ａの平面方向にスライドさせると、シート３０が移植対象部位に貼り付く。この移植手法は、水分に触れたときに水の表面張力や自己溶解に伴う粘着性を生ずるタイプのシート３０に有用である。 The transplantation of the sheet 30 may be performed in a different manner as well as simply pressing the sheet support surface portion 13a against the transplantation target site. As an example, the length of the sheet 30 is set so as to slightly protrude from the leading end of the sheet support surface portion 13a when the sheet support 13 supports the sheet 30. Then, in a state where the sheet support 13 is expanded and the sheet 30 is brought into contact with the site to be transplanted, the portion protruding from the front end of the sheet support surface portion 13a of the sheet 30 is pressed with forceps or the like, and separated from the sheet protruding portion. Thus, when the sheet support 13 is slid in the plane direction of the sheet support surface portion 13a (toward the connection portion 13b), the sheet 30 sticks to the transplant target site. This transplantation technique is useful for the type of sheet 30 that produces a surface tension of water and adhesiveness due to self-dissolution when exposed to moisture.

シート３０の移植が完了したら、スライド部材１２を引き込み方向へスライドさせて図２及び図１５のようにシート支持体１３を外筒１１内に収納し、運搬投与器具１０を体内から引き抜く。なお、仮にシート支持体１３を外筒１１内に収納しないまま引き抜いたとしても、トラカールが外筒１１と同様に機能してシート支持体１３が筒状に変形されるため、生体への障害や運搬投与器具１０の破損を起こさずに体内から引抜くことができる。引き抜き後、スライド部材１２を分解位置までスライドさせてシート支持体１３と接続部材１７をスライド部材１２から取り外す。さらなる移植（治療）を必要とする場合には、シート支持体１３を有する新しい脱着部を取り付けて再度処置を行う。 When the transplantation of the sheet 30 is completed, the slide member 12 is slid in the retracting direction, the sheet support 13 is accommodated in the outer cylinder 11 as shown in FIGS. 2 and 15, and the delivery device 10 is pulled out from the body. Even if the sheet support 13 is pulled out without being stored in the outer cylinder 11, the trocar functions in the same manner as the outer cylinder 11 and the sheet support 13 is deformed into a cylindrical shape. The delivery device 10 can be pulled out from the body without causing damage. After pulling out, the slide member 12 is slid to the disassembly position, and the seat support 13 and the connection member 17 are removed from the slide member 12. When further transplantation (treatment) is required, a new attachment / detachment portion having the sheet support 13 is attached and the treatment is performed again.

以上のように、本実施形態の運搬投与器具１０によれば、シート３０を筒状にして外筒１１内に格納し、この外筒１１の挿入によって移植部位までシート３０を運搬するため、シート３０を展開した状態で運搬する手法に比べて人体への侵襲の度合いを低く抑えることができる。そして、移植部位に達したらスライド部材１２を突出方向に押し出すことで、シート３０を支持するシート支持体１３が自己の形状維持性によって自動的に展開されるので、鉗子などを用いた従来の手法に比べて、極めて容易かつ確実にシート３０の移植作業を行うことができる。そして、運搬投与器具１０は、外筒１１内でのスライド部材１２の進退移動に応じて柔軟性を持つシート支持体１３が展開状態と筒状の収納状態とに変形されるという簡単な構造であるため、動作不良などの不具合が生じるおそれが少ない。また、部品点数が少なく、個々の部品も安価な材料で形成可能であるため、製造コストを低く抑えることができる。 As described above, according to the transport administration device 10 of the present embodiment, the sheet 30 is stored in the outer cylinder 11 in a cylindrical shape, and the sheet 30 is transported to the transplant site by insertion of the outer cylinder 11. The degree of invasion to the human body can be reduced compared to the method of transporting 30 in a deployed state. When the transplant site is reached, the sheet support 13 supporting the sheet 30 is automatically deployed by pushing out the slide member 12 in the protruding direction, so that the conventional method using forceps or the like is used. Compared to the above, the sheet 30 can be transplanted extremely easily and reliably. The delivery device 10 has a simple structure in which the flexible sheet support 13 is deformed into an expanded state and a cylindrical storage state in accordance with the forward and backward movement of the slide member 12 in the outer cylinder 11. Therefore, there is little risk of malfunctions such as malfunctions. In addition, since the number of components is small and individual components can be formed from inexpensive materials, the manufacturing cost can be kept low.

図１６及び図１７は、より幅広のシート状治療物質を支持可能な、別実施形態を示している。この実施形態では、外筒１１１の内部に、内周面から内径方向に向けて突設された隔壁部１１１ｂが形成されている。外筒１１１の先端部は傾斜端面１１１ａであり、シート支持体１１３が外筒１１１内に収納されるときに、この傾斜端面１１１ａに対して幅徐変部１１３ｃが当接し徐々に筒状になっていくという基本構造は、先の実施形態と共通である。先の実施形態では、外筒１１に収納された状態で筒状になったシート支持体１３に重なり部分を生じさせないために、シート支持体１３におけるシート支持面部１３ａの横幅サイズは、外筒１１の内周サイズ以下に設定されていた。これに対し外筒１１１では、隔壁部１１１ｂを設けることによってシート支持体１１３に対する支持面積（シート支持体を支持する外筒内部の表面積）が増大されているため、図１７に示すように、外筒１１１の単純な内周サイズよりも幅広なシート支持面部１１３ａを有するシート支持体１１３を、重なりを生じることなく収納することができる。 16 and 17 show another embodiment that can support a wider sheet of therapeutic substance. In this embodiment, a partition wall portion 111 b that protrudes from the inner peripheral surface toward the inner diameter direction is formed inside the outer cylinder 111. The distal end portion of the outer cylinder 111 is an inclined end surface 111a, and when the sheet support 113 is stored in the outer cylinder 111, the width gradually changing portion 113c comes into contact with the inclined end surface 111a and gradually becomes cylindrical. The basic structure is the same as in the previous embodiment. In the previous embodiment, the width of the sheet support surface portion 13a of the sheet support 13 is set to be the outer cylinder 11 in order to prevent an overlapping portion from being generated in the cylindrical sheet support 13 accommodated in the outer cylinder 11. It was set below the inner circumference size. On the other hand, in the outer cylinder 111, since the support area for the sheet support 113 ( surface area inside the outer cylinder that supports the sheet support ) is increased by providing the partition 111b, as shown in FIG. The sheet support 113 having the sheet support surface 113a wider than the simple inner peripheral size of the cylinder 111 can be stored without causing overlap.

また、先の実施形態では、シート支持体１３の展開状態でシート支持面部１３ａは外筒１１の軸線と略平行な平面状になっているが、展開時のシート支持体の角度は任意に設定することができる。図１８はその一例を示しており、嵌合段部２１７ｃと離間移動規制突起２１７ｄを介してスライド部材１２に着脱可能な接続部材２１７は、支持ブロック２１７Ａと押さえブロック２１７Ｂの２部材からなっている。支持ブロック２１７Ａと押さえブロック２１７Ｂは、ねじ孔２１７ａに螺合するねじ２２０を介して固定される。支持ブロック２１７Ａと押さえブロック２１７Ｂの間には、外筒１１の軸線に対して傾斜する傾斜支持平面２１７ｅが形成されており、シート支持体２１３は、この傾斜支持平面２１７ｅに接続部２１３ｂを載せた状態で支持ブロック２１７Ａと押さえブロック２１７Ｂに挟着されることによって保持される。シート支持体２１３のシート支持面部２１３ａは、傾斜支持平面２１７ｅの延長上に位置するため、展開状態でのシート支持面部２１３ａには、外筒１１の軸線に対して傾斜支持平面２１７ｅの傾斜角に応じた所定の傾斜が与えられる。 In the previous embodiment, the sheet support surface portion 13a has a planar shape substantially parallel to the axis of the outer cylinder 11 when the sheet support 13 is deployed, but the angle of the sheet support during deployment is arbitrarily set. can do. FIG. 18 shows an example thereof. The connection member 217 that can be attached to and detached from the slide member 12 via the fitting step 217c and the separation movement restricting projection 217d is composed of two members, a support block 217A and a holding block 217B. . The support block 217A and the pressing block 217B are fixed via screws 220 that are screwed into the screw holes 217a. An inclined support plane 217e that is inclined with respect to the axis of the outer cylinder 11 is formed between the support block 217A and the holding block 217B, and the seat support 213 has a connecting portion 213b mounted on the inclined support plane 217e. In this state, it is held by being sandwiched between the support block 217A and the holding block 217B. Since the sheet support surface portion 213a of the sheet support 213 is positioned on the extension of the inclined support plane 217e, the sheet support surface portion 213a in the unfolded state has an inclination angle of the inclined support plane 217e with respect to the axis of the outer cylinder 11. A corresponding predetermined slope is provided.

先に説明した通り、図１６及び図１７の実施形態では、隔壁部１１１ｂを形成して外筒１１１の内部のシート支持体を支持する表面積を増大させることによって、外筒１１１の単純な内周長よりも幅広のシート支持体１１３を、外筒１１１内に確実に収納可能とさせている。これに対し、シート支持体側の形状設定によって、幅広のシート支持体をスムーズに収納できるようにした実施形態を図１９以下に示す。 As described above, in the embodiment of FIGS. 16 and 17, the partition wall portion 111 b is formed to increase the surface area for supporting the sheet support inside the outer tube 111, so that the simple inner periphery of the outer tube 111 is formed. The sheet support 113 wider than the length can be securely stored in the outer cylinder 111. On the other hand, an embodiment in which a wide sheet support can be smoothly stored by setting the shape on the sheet support side is shown in FIG. 19 and subsequent figures.

図１９及び図２０に示すシート支持体３１３は、接続部３１３ｂを介してスライド部材３１２の先端部に支持され、外筒３１１内に収納されるときに、傾斜端面３１１ａに対して幅徐変部３１３ｃが当接して徐々に筒状になっていくという基本構造は、先の実施形態と同じものである。シート支持体３１３は、外筒３１１の軸線と平行でスライド部材３１２との接続部３１３ｂを通るシート支持体３１３の中心線Ｃに関して、左右非対称な形状を備えている点を特徴としている。この非対称形状部は、幅徐変部３１３ｃからシート支持面部３１３ａの両縁部（側部）に至るシート支持体３１３の基端側領域に形成されており、図１９に示すように、中心線Ｃを挟んで位置する一方の通常形状部Ｋ１に対して、他方は一部が切除された態様の幅狭形状部Ｋ２となっている。 19 and 20 is supported by the distal end portion of the slide member 312 via the connection portion 313b, and when the seat support member 313 is housed in the outer cylinder 311, the width gradually changing portion with respect to the inclined end surface 311a. The basic structure in which 313c abuts and gradually becomes cylindrical is the same as the previous embodiment. The sheet support 313 is characterized in that it has an asymmetric shape with respect to the center line C of the sheet support 313 that is parallel to the axis of the outer cylinder 311 and passes through the connecting portion 313b with the slide member 312. This asymmetrical shape part is formed in the base end side region of the sheet support 313 from the width gradually changing part 313c to both edges (side parts) of the sheet support surface part 313a, and as shown in FIG. In contrast to one normal shape portion K1 that is located across C, the other is a narrow shape portion K2 that is partially cut away.

シート支持体３１３の左右方向の幅は、外筒３１１の内周長よりも大きく、シート支持体３１３を筒状の収納形状にしたときには、シート支持面部３１３ａの両縁部付近の一部領域が重なる状態になる。ここで、シート支持体３１３が中心線Ｃに関して左右対称な形状であると、筒状に変形される際に、シート支持面部３１３ａの両縁部（エッジ部分）が干渉して引っ掛かりを生じ、スムーズな変形が妨げられるおそれがある。これに対し、通常形状部Ｋ１と幅狭形状部Ｋ２という左右非対称な基端側形状を持たせたシート支持体３１３であると、図２０に示すように、外筒３１１への収納時に、必ず幅狭形状部Ｋ２側の縁部が通常形状部Ｋ１の下側（内側）に潜り込む態様で変形が行われるので、シート支持面部３１３ａの両縁部が干渉するおそれがない。よって、外筒３１１の内周長よりも幅広のシート支持体３１３を、スムーズに外筒３１１内へ収納させることができる。 The width in the left-right direction of the sheet support 313 is larger than the inner peripheral length of the outer cylinder 311, and when the sheet support 313 is formed in a cylindrical storage shape, partial areas near both edges of the sheet support surface 313a are Overlapping state. Here, if the sheet support 313 has a symmetrical shape with respect to the center line C, when the sheet support 313 is deformed into a cylindrical shape, both edge portions (edge portions) of the sheet support surface portion 313a interfere with each other, and are caught smoothly. May be hindered. On the other hand, in the case of the sheet support body 313 having the left and right asymmetric base end side shapes of the normal shape portion K1 and the narrow shape portion K2, as shown in FIG. Since the deformation is performed in such a manner that the edge portion on the narrow shape portion K2 side sinks into the lower side (inside) of the normal shape portion K1, there is no possibility that both edge portions of the sheet support surface portion 313a interfere with each other. Therefore, the sheet support 313 wider than the inner peripheral length of the outer cylinder 311 can be smoothly accommodated in the outer cylinder 311.

図２１は、図１９及び図２０のシート支持体３１３と同様に、外筒４１１の軸線と平行でスライド部材４１２との接続部４１３ｂを通る中心線Ｃに関して、左右非対称な形状を有するシート支持体４１３を示している。先のシート支持体３１３が、基端側の一部のみを非対称形状としていたのに対し、このシート支持体４１３は、スライド部材４１２に接続する基端部側から先端部に至るまで、シート支持面部４１３ａの全体が非対称形状になっている点が異なる。すなわち、シート支持体４１３は、中心線Ｃを挟んで互いに幅の異なる幅広部Ｈ１と幅狭部Ｈ２を有する形状となっている。この形状のシート支持体４１３は、傾斜端面４１１ａと幅徐変部４１３ｃの当接関係によって筒状にされながら外筒４１１内へ収納されるときに、幅狭部Ｈ２が幅広部Ｈ１の下側（内側）に潜り込む態様で変形が行われるので、シート支持面部４１３ａの両縁部が干渉するおそれがなく、外筒４１１の内周長に対して幅広のシート支持体４１３において、スムーズに収納動作を行わせることができる。 FIG. 21 shows a sheet support having a left-right asymmetric shape with respect to a center line C parallel to the axis of the outer cylinder 411 and passing through the connecting portion 413b, similar to the sheet support 313 of FIGS. 413 is shown. Whereas the previous sheet support 313 has an asymmetrical shape only on the base end side, this sheet support 413 supports the sheet from the base end side connected to the slide member 412 to the front end. The difference is that the entire surface portion 413a has an asymmetric shape. That is, the sheet support 413 has a shape having a wide portion H1 and a narrow portion H2 having different widths with the center line C interposed therebetween. When the sheet support 413 having this shape is accommodated in the outer cylinder 411 while being formed into a cylindrical shape due to the contact relationship between the inclined end surface 411a and the gradually changing width portion 413c, the narrow portion H2 is located below the wide portion H1. Since the deformation is performed in such a manner as to sink into the (inner side), there is no possibility that both edges of the sheet support surface portion 413a interfere with each other, and the sheet support body 413 that is wide with respect to the inner peripheral length of the outer cylinder 411 can be stored smoothly. Can be performed.

なお、図１９及び図２０に示すシート支持体３１３や図２１に示すシート支持体４１３では、徐変部３１３ｃ、４１３ｃは、中心線Ｃを挟んで略対称な形状（角度）の縁部を有しているが、幅徐変部の左右縁部の相対的な形状（角度）を異ならせることによって、収納時におけるシート支持体両縁の重なり部分の干渉を防ぐことも可能である。 In the sheet support 313 shown in FIGS. 19 and 20 and the sheet support 413 shown in FIG. 21, the gradual change portions 313c and 413c have edges of a substantially symmetrical shape (angle) across the center line C. However, by making the relative shapes (angles) of the left and right edge portions of the width gradually changing portion different, it is also possible to prevent interference between overlapping portions of both edges of the sheet support during storage.

以上、図示実施形態に基づいて説明したが、本発明は図示実施形態に限定されるものではなく、発明の要点を逸脱しない限りにおいて異なる形態とすることが可能である。例えば、図示実施形態においては、クランク状の規制溝１２ｃとスライド制御ねじ２２の係合関係によって、スライド部材１２のスライド方向及びスライド量を規制しているが、スライド部材１２のスライドガイド構造として、これ以外の機械的構造を用いることもできる。 As mentioned above, although demonstrated based on illustration embodiment, this invention is not limited to illustration embodiment, It is possible to set it as a different form unless it deviates from the main point of invention. For example, in the illustrated embodiment, the sliding direction and the sliding amount of the slide member 12 are regulated by the engagement relationship between the crank-shaped regulation groove 12c and the slide control screw 22, but as a slide guide structure of the slide member 12, Other mechanical structures can also be used.

また、図示実施形態においては、スライド部材１２を進退させるための把持操作部として、一対の指掛けフランジ１４ａを有するグリップ部１４と指掛け部１５を備え、注射器と同様の操作性を実現しているが、これに変えて、いわゆるガングリップタイプなど、異なる形態の把持操作部を用いることも可能である。 In the illustrated embodiment, the grip operation unit for advancing and retracting the slide member 12 includes a grip unit 14 having a pair of finger-hanging flanges 14a and a finger-holding unit 15, and realizes the same operability as a syringe. Instead of this, it is also possible to use different types of grip operation units such as a so-called gun grip type.

本発明による治療用物質の運搬投与器具の一実施形態を示す、外筒の先端からシート支持体が突出し展開された状態の斜視図である。It is a perspective view of the state which the sheet support body protruded from the front-end | tip of an outer cylinder, and was expand | deployed which shows one Embodiment of the delivery administration apparatus of the therapeutic substance by this invention. シート支持体を外筒内に収納した状態の運搬投与器具を示す斜視図である。It is a perspective view which shows the conveyance administration instrument of the state which accommodated the sheet | seat support body in the outer cylinder. 図１のシート支持体の突出展開状態における運搬投与器具の平面図である。It is a top view of the conveyance administration apparatus in the protrusion expansion | deployment state of the sheet | seat support body of FIG. 図１のシート支持体の突出展開状態における運搬投与器具の側面図である。It is a side view of the conveyance administration apparatus in the protrusion expansion | deployment state of the sheet | seat support body of FIG. 運搬投与器具の把持操作部付近を拡大した部分斜視図である。It is the fragmentary perspective view which expanded the grasping operation part vicinity of a conveyance administration instrument. 運搬投与器具の把持操作部付近の側断面図である。It is side sectional drawing of the holding | grip operation part vicinity of a delivery administration apparatus. 外筒の一部を断面として示した、シート支持体の突出展開状態における運搬投与器具の先端部付近の斜視図である。It is a perspective view near the front-end | tip part of the conveyance administration apparatus in the protrusion expansion | deployment state of the sheet | seat support body which showed a part of outer cylinder as a cross section. シート支持体の突出展開状態における、スライド部材と接続部材の結合構造付近を示す側断面図である。It is a sectional side view which shows the joint structure vicinity of a slide member and a connection member in the protrusion expansion | deployment state of a sheet | seat support body. 接続部材とシート支持体の結合体をスライド部材の先端部から取り外した状態の分解斜視図である。It is a disassembled perspective view of the state which removed the coupling body of the connection member and the sheet | seat support body from the front-end | tip part of the slide member. 接続部材とシート支持体を分解した状態の斜視図である。It is a perspective view of the state which decomposed | disassembled the connection member and the sheet | seat support body. 運搬投与器具の使用に際して、シート支持体が外筒の先端から突出されて平面状に展開された状態を示す、外筒先端付近の部分斜視図である。FIG. 6 is a partial perspective view of the vicinity of the outer cylinder tip, showing a state in which the sheet support protrudes from the tip of the outer cylinder and is developed in a planar shape when using the transport administration device. 図１１の状態からスライド部材が引き込み方向に若干移動され、シート支持体が展開状態から筒状状態への変形を開始した状態を示す、外筒先端付近の部分斜視図である。FIG. 12 is a partial perspective view of the vicinity of the front end of the outer cylinder showing a state in which the slide member is slightly moved in the retracting direction from the state of FIG. 11 and the sheet support starts to deform from the expanded state to the cylindrical state. 図１２の状態よりもスライド部材が引き込み方向に移動され、シート支持体の筒状状態への変形が進んだ状態を示す、外筒先端付近の部分斜視図である。FIG. 13 is a partial perspective view in the vicinity of a front end of the outer cylinder showing a state in which the slide member is moved in the retracting direction than in the state of FIG. 図１３の状態からさらにスライド部材が引き込み方向に移動され、シート支持体の筒状状態への変形が進んだ状態を示す、外筒先端付近の部分斜視図である。FIG. 14 is a partial perspective view in the vicinity of a front end of the outer cylinder showing a state in which the slide member is further moved in the retracting direction from the state of FIG. 13 and the sheet support is deformed into the cylindrical state. シート支持体の全体が筒状となって外筒の内部に収納された状態を示す、外筒先端付近の部分斜視図である。FIG. 3 is a partial perspective view of the vicinity of a front end of the outer cylinder showing a state in which the entire sheet support is formed in a cylindrical shape and is housed inside the outer cylinder. 外筒内に隔壁部を備えて幅広のシート支持体を収納可能とした実施形態を示す、外筒先端付近の部分斜視図である。It is a fragmentary perspective view of the outer cylinder vicinity showing the embodiment which provided the partition part in the outer cylinder and was able to accommodate a wide sheet | seat support body. 図１６の外筒内に幅広のシート支持体を収納した状態の断面図である。It is sectional drawing of the state which accommodated the wide sheet | seat support body in the outer cylinder of FIG. 図８とはシート支持体の取り付け角度を異ならせた実施形態を示す、スライド部材と接続部材の結合構造付近の側断面図である。FIG. 9 is a side sectional view of the vicinity of the coupling structure of the slide member and the connecting member, showing an embodiment in which the mounting angle of the sheet support is different from that of FIG. シート支持体の基端部付近を左右非対称に形成した実施形態を示す、シート支持体の展開状態の斜視図である。It is a perspective view of the unfolded state of a sheet support showing an embodiment in which the vicinity of the base end portion of the sheet support is formed asymmetrically left and right. 図１９の左右非対称形状のシート支持体を筒状に変形させている途中の状態を示す斜視図である。FIG. 20 is a perspective view illustrating a state in the middle of deforming the left-right asymmetric sheet support of FIG. 19 into a cylindrical shape. シート支持面部の略全体を左右非対称に形成した実施形態を示す、シート支持体の展開状態の斜視図である。It is a perspective view of the unfolded state of a sheet support showing an embodiment in which substantially the entire sheet support surface portion is formed asymmetrically left and right.

Explanation of symbols

１０運搬投与器具
１１外筒
１１ａ傾斜端面
１２スライド部材
１２ａ嵌合段部
１２ｂ離間移動規制凹部
１２ｃ規制溝（移動制限手段）
１３シート支持体（シート支持部材）
１３ａシート支持面部
１３ｂ接続部
１３ｃ幅徐変部
１３ｄ貫通孔
１３ｅ終端曲げ部
１４グリップ部
１４ａ指掛けフランジ
１５指掛け部
１６Ｏリング
１７接続部材
１７ａねじ孔
１７ｂ差し込み溝
１７ｃ嵌合段部
１７ｄ離間移動規制突起
１７ｅ支持平面
２２スライド制御ねじ（移動制限手段）
３０シート状の治療用物質
１１１外筒
１１１ｂ隔壁部
１１３シート支持体（シート支持部材）
２１３シート支持体（シート支持部材）
２１７接続部材
２１７Ａ支持ブロック
２１７Ｂ押さえブロック
２１７ｅ支持平面
３１１外筒
３１２スライド部材
３１３シート支持体（シート支持部材）
４１１外筒
４１２スライド部材
４１３シート支持体（シート支持部材）
Ｃシート支持体の中心線
Ｈ１幅広部
Ｈ２幅狭部
Ｋ１通常形状部
Ｋ２幅狭形状部 DESCRIPTION OF SYMBOLS 10 Delivery administration apparatus 11 Outer cylinder 11a Inclined end surface 12 Slide member 12a Fitting step part 12b Separation movement control recessed part 12c Control groove (movement restriction means)
13 Sheet Support (Sheet Support Member)
13a Seat support surface portion 13b Connection portion 13c Gradually varying portion 13d Through hole 13e Terminal bending portion 14 Grip portion 14a Finger hook flange 15 Finger hook portion 16 O ring 17 Connection member 17a Screw hole 17b Inserting groove 17c Fitting step portion 17d Separation movement restricting projection 17e Support plane 22 Slide control screw (movement limiting means)
30 Sheet-shaped therapeutic substance 111 Outer cylinder 111b Partition wall 113 Sheet support (sheet support member)
213 Sheet support (sheet support member)
217 Connecting member 217A Support block 217B Pressing block 217e Support plane 311 Outer cylinder 312 Slide member 313 Sheet support (sheet support member)
411 outer cylinder 412 slide member 413 sheet support (sheet support member)
C sheet support center line H1 wide portion H2 narrow portion K1 normal shape portion K2 narrow shape portion

Claims

Cylindrical outer cylinder;
A slide member supported in the outer cylinder so as to be slidable in the axial direction; and a free member which is provided at the distal end portion of the slide member and supports the sheet-like therapeutic substance and protrudes from the distal end portion of the outer cylinder In the state, it is maintained in a flat developed shape, and when it is moved inward of the outer cylinder in response to the sliding movement of the slide member, it contacts the tip of the outer cylinder and deforms into a cylindrical shape A sheet support member housed in
The seat support member can be attached to and detached from the slide member in the radial direction of the outer cylinder, and in a normal use state, the slide member can be moved within a range that is restricted by the inner peripheral surface of the outer cylinder. A device for transporting and administering a therapeutic substance, characterized by comprising movement restriction means for restricting the area .

Cylindrical outer cylinder;
  A slide member supported in the outer cylinder so as to be slidable in the axial direction; and
  A sheet-shaped therapeutic substance is supported to be provided at the distal end of the slide member, and in a free state protruding from the distal end portion of the outer cylinder, it is maintained in a flat unfolded shape and responds to the sliding movement of the slide member. A sheet support member that is accommodated in the outer cylinder while being deformed into a cylindrical shape while abutting against the tip of the outer cylinder when moved inwardly of the outer cylinder;
  A therapeutic substance delivery / administration device comprising a partition for increasing a surface area of an outer cylinder supporting a sheet support inside the outer cylinder.

3. The therapeutic substance delivery / administration device according to claim 1 or 2, wherein the sheet support member gradually supports a sheet-like therapeutic substance and a connection part between the support surface part and the slide member. And a width gradually changing portion that narrows the lateral width, and when moved in the inner direction of the outer cylinder from the expanded state, the sheet supporting member is moved by the contact between the width gradually changing portion and the distal end portion of the outer cylinder. A device for transporting and administering a therapeutic substance that is transformed into a cylindrical shape.

4. The therapeutic substance delivery / administration device according to claim 3, wherein an inclined end surface that is not parallel to a plane perpendicular to the axis of the outer cylinder is formed at a distal end portion of the outer cylinder. .

The therapeutic substance delivery administration device according to any one of claims 1 to 4 , further comprising a connecting member interposed between the seat support member and the slide member, wherein the seat support member is projected from the outer cylinder. Thus, the therapeutic substance delivery / administration device supported by the connecting member so as to have a planar shape substantially parallel to the axis of the outer cylinder.

The therapeutic substance delivery administration device according to any one of claims 1 to 4 , further comprising a connecting member interposed between the seat support member and the slide member, wherein the seat support member is projected from the outer cylinder. Then, the therapeutic substance delivery administration device supported by the connecting member so as to have a planar shape inclined with respect to the axis of the outer cylinder.

6. The therapeutic substance delivery / administration device according to any one of claims 1 to 5 , wherein the unfolded sheet support member is in relation to a center line passing through the connecting portion with the slide member in parallel with the axis of the outer cylinder. A therapeutic delivery device for a therapeutic substance having an asymmetric shape.

8. The therapeutic substance delivery / administration device according to claim 7, wherein the seat support member has a non-symmetrical shape in a partial region on the base end side connected to the slide member. .

8. The therapeutic substance delivery / administration device according to claim 7, wherein the sheet support member is entirely asymmetric from the proximal end side to the distal end part connected to the slide member. Administration device.