JP5069562B2 - 組換えヒトT2RNaseおよびその使用 - Google Patents

組換えヒトT2RNaseおよびその使用 Download PDF

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JP5069562B2
JP5069562B2 JP2007534175A JP2007534175A JP5069562B2 JP 5069562 B2 JP5069562 B2 JP 5069562B2 JP 2007534175 A JP2007534175 A JP 2007534175A JP 2007534175 A JP2007534175 A JP 2007534175A JP 5069562 B2 JP5069562 B2 JP 5069562B2
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rnase
cells
cell
tumor
actin
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JP2008514224A (ja
JP2008514224A5 (cg-RX-API-DMAC7.html
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レヴァヴァ ロイズ,
ベティ シュワルツ,
パトリシア スミルノフ,
オデド ショセヨヴ,
Original Assignee
イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
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    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
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    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
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    • A61P35/04Antineoplastic agents specific for metastasis
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Cardiology (AREA)
  • Biomedical Technology (AREA)
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JP2007534175A 2004-09-29 2005-09-28 組換えヒトT2RNaseおよびその使用 Expired - Fee Related JP5069562B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61370204P 2004-09-29 2004-09-29
US60/613,702 2004-09-29
PCT/IL2005/001041 WO2006035439A2 (en) 2004-09-29 2005-09-28 Recombinant human t2 rnase and uses thereof

Publications (3)

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JP2008514224A JP2008514224A (ja) 2008-05-08
JP2008514224A5 JP2008514224A5 (cg-RX-API-DMAC7.html) 2008-11-06
JP5069562B2 true JP5069562B2 (ja) 2012-11-07

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JP2007534175A Expired - Fee Related JP5069562B2 (ja) 2004-09-29 2005-09-28 組換えヒトT2RNaseおよびその使用

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US (1) US8039240B2 (cg-RX-API-DMAC7.html)
EP (1) EP1805319B1 (cg-RX-API-DMAC7.html)
JP (1) JP5069562B2 (cg-RX-API-DMAC7.html)
AU (1) AU2005288527B9 (cg-RX-API-DMAC7.html)
BR (1) BRPI0516302A (cg-RX-API-DMAC7.html)
CA (1) CA2582041C (cg-RX-API-DMAC7.html)
ES (1) ES2524601T3 (cg-RX-API-DMAC7.html)
WO (1) WO2006035439A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200703313B (cg-RX-API-DMAC7.html)

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ATE421856T1 (de) * 1999-08-30 2009-02-15 Yissum Res Dev Co Gebrauch einer ribonuclease der t2-familie mit actin-bindender aktivität zur hemmung und/oder der umkehrung von proliferation
US7811981B2 (en) 1999-08-30 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
WO2008016623A2 (en) * 2006-08-01 2008-02-07 Dingee H Clay Iv Improved drying system
EA201100610A1 (ru) * 2008-10-30 2011-10-31 Йиссум Ресёрч Девелопмент Компани Оф Дзе Хебрю Юниверсити Оф Иерусалим Лтд. Эффективная экспрессия укороченного человеческого белка rnaset2 в e.coli
WO2011084995A2 (en) * 2010-01-05 2011-07-14 Stratasys, Inc. Support cleaning system
CN105764567B (zh) 2013-09-27 2019-08-09 梅维昂医疗系统股份有限公司 粒子束扫描
US9962560B2 (en) 2013-12-20 2018-05-08 Mevion Medical Systems, Inc. Collimator and energy degrader
US10675487B2 (en) 2013-12-20 2020-06-09 Mevion Medical Systems, Inc. Energy degrader enabling high-speed energy switching
WO2015114633A1 (en) 2014-01-30 2015-08-06 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenes is and treating medical conditions associated with same
US9661736B2 (en) 2014-02-20 2017-05-23 Mevion Medical Systems, Inc. Scanning system for a particle therapy system
US10786689B2 (en) 2015-11-10 2020-09-29 Mevion Medical Systems, Inc. Adaptive aperture
KR20240095481A (ko) 2016-03-17 2024-06-25 세다르스-신나이 메디칼 센터 Rnaset2를 통한 염증성 장 질환의 진단 방법
WO2018009779A1 (en) 2016-07-08 2018-01-11 Mevion Medical Systems, Inc. Treatment planning
US11103730B2 (en) 2017-02-23 2021-08-31 Mevion Medical Systems, Inc. Automated treatment in particle therapy
WO2019006253A1 (en) 2017-06-30 2019-01-03 Mevion Medical Systems, Inc. CONFIGURABLE COLLIMATOR CONTROLLED BY LINEAR MOTORS
CA3121162A1 (en) * 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith
US11291861B2 (en) 2019-03-08 2022-04-05 Mevion Medical Systems, Inc. Delivery of radiation by column and generating a treatment plan therefor

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NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) * 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) * 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
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US3867517A (en) * 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
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US7101839B1 (en) * 1999-08-30 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
KR100677108B1 (ko) 2003-06-12 2007-02-01 삼성전자주식회사 정보 저장매체

Also Published As

Publication number Publication date
CA2582041A1 (en) 2006-04-06
US20080131419A1 (en) 2008-06-05
BRPI0516302A (pt) 2008-09-02
ES2524601T3 (es) 2014-12-10
EP1805319A4 (en) 2009-12-16
AU2005288527B2 (en) 2011-02-03
WO2006035439A2 (en) 2006-04-06
JP2008514224A (ja) 2008-05-08
WO2006035439A3 (en) 2007-06-28
HK1100329A1 (en) 2007-09-14
AU2005288527B9 (en) 2011-07-28
EP1805319B1 (en) 2014-09-03
ZA200703313B (en) 2008-09-25
US8039240B2 (en) 2011-10-18
EP1805319A2 (en) 2007-07-11
CA2582041C (en) 2015-08-04
AU2005288527A1 (en) 2006-04-06

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