JP5010193B2 - Tooth bleach and method for producing tooth bleach - Google Patents

Description

The present invention relates organic material deposited in the tooth, for example food, beverages, than conventional methods coloring substances derived from tobacco Safety, easily and efficiently process of tooth bleaching agents and tooth bleaching agent to be removed.

  In recent years, as people's health-consciousness has become stronger, there is an increasing demand for cosmetic surgery and cosmetic dentistry to improve not only the conventional treatment of diseases but also the aesthetics of the body. Among them, the face is the place where people pay the most attention, and the improvement of aesthetics is what many people want. Young women, in particular, are very dissatisfied with the fact that their teeth cannot be as white as they think, even though they can improve the aesthetics of their face other than their teeth, such as makeup for their eyes and lips. Thus, dentifrices that make teeth white have formed a large market, but since their effects are limited, techniques for whitening teeth safely, simply and effectively are required.

  As a technique for whitening teeth, there is a method (Japanese Patent Laid-Open No. 5-320033) in which high-concentration hydrogen peroxide (30-35% concentration) is mixed with anhydrous silicic acid and applied to the tooth surface. Since whiteness is a so-called cloudy “ground glass”, there is a problem that the teeth that are originally creamy like Japanese people have a strong sense of incongruity and many patients complain of dissatisfaction.

  In addition, high concentration of hydrogen peroxide is a powerful drug and its properties are liquid, and there is a problem in handling that even a single drop causes intense pain and inflammation when it adheres to the gums and mucous membranes. For this reason, the dentist needs to be treated with great care, so it is difficult to say that it is a simple treatment, and the cost of the patient is high because each treatment takes almost one hour. There is a problem.

  In order to solve the problems caused by using the high-concentration hydrogen peroxide solution described above, a technology has been developed that makes it possible to bleach teeth even with low-concentration hydrogen peroxide using photocatalytic titanium dioxide. (Japanese Patent No. 3030380). However, this technique requires a light source for causing titanium dioxide to exhibit a bleaching action, and has a problem that a sufficient bleaching effect cannot be obtained if the light energy is weak. Furthermore, it cannot be said that the treatment time has been shortened compared with the case of using conventional high-concentration hydrogen peroxide, and the burden on the patient has not been significantly reduced.

  As an attempt to overcome the weakness of titanium dioxide that requires a large amount of light source, gold-supported titanium oxide has been developed (Japanese Patent Laid-Open No. 2005-343813). Although the bleaching effect can be expressed with less energy than conventional titanium dioxide, there is no change in the presence of a light source for exerting the bleaching action, and it cannot be said that it is a simple tooth bleaching method.

As a technique other than the above, a gel mixed with a bleaching agent (hydroxymethylcellulose, carboxypolymethylene, polyvinylpyrrolidone, etc.) is injected into a tray (or mouthpiece) made to fit the shape of the patient's teeth. In addition, there is a technique for whitening teeth by attaching the tray to teeth (Patent Document 1).
JP-A-8-113520

As a condition required for the technology to whiten teeth, it is safe, effective in a short time, and does not require special equipment to exert the bleaching effect and can be handled by both dentists and patients It is easy and the patient's financial burden is low. Method described above does not require an instrument such as a light source compared to the technique described above, simply and relatively cheaply some of the above conditions in that it can whiten teeth meets, but bleach in fluid Due to the nature of being, there are the following problems.

(1) Hydrogen peroxide and urea peroxide bleach are in gel form, so if you put the tray on your teeth for a long time, there is a risk that the bleach will flow out and swallow, and the effect will be lost rapidly. . For this reason, this method has to limit the time for the patient to put the tray on the teeth to a few hours, and there is no guarantee that the teeth can be bleached reliably. It takes time to reach it.
(2) When bleach is poured into the tray and attached to the teeth, there is a high risk that extra bleach will flow into the oral cavity and be swallowed.
(3) The operation of injecting the bleaching agent into the tray each time and the operation of cleaning the tray after use are forced on the patient, and the operation is very complicated.

The present inventor, who has studied diligently about the bleaching method of teeth in view of the problem caused by the fact that the bleaching agent is a fluid, pays attention to the fact that the effect of the bleaching agent on whitening teeth is based on active oxygen. By solidifying a bleaching substance capable of generating active oxygen, it is safer than the prior art and can be effective in a short period of time. It aims at providing the manufacturing method of the tooth bleaching agent and tooth bleaching agent which are easy.
Note that a bleaching agent is a substance that exhibits a bleaching effect. Even if the bleaching effect is increased by a substance constituting the bleaching apparatus, the bleaching apparatus does not have a bleaching ability unless it contains a bleaching agent.

The present invention according to claim 1 configured to solve the above-described problem is an activity comprising one or more polysaccharides selected from karaya gum, gum arabic, kua gum, and gellan gum, and in the form of a fine powder. It consists of a tooth bleaching agent having oxygen generation ability .

The means constituting the present invention according to claim 2 comprises one or more polysaccharides selected from karaya gum, gum arabic, kua gum, and gellan gum, and a hydrogen peroxide aqueous solution having a concentration of 3 to 35% by weight. It consists of a method for producing a tooth bleaching agent having an active oxygen generating ability, which is mixed at a ratio of 20 to 50% by weight to obtain a uniform state, dried by natural drying or air drying, and then formed into a fine powder by a fine powder treatment .

Since the present invention is configured as described above, the following effects can be obtained.
(1) tooth bleaching agent, because consists fine powder of polysaccharide imparted with active oxygen generation ability, safety in use differs from the prior art fluid is rather high, the handling is extremely easy.
(2) Since the tooth bleaching agent is a fine powdery solid, it is possible to mold a tooth bleaching mounting body that adheres to and covers the tooth surface by forming an admixture with the polymer resin . The risk of the bleaching agent eluting into the oral cavity can be greatly reduced by the tooth bleaching attachment, and the bleaching agent can be held on the tooth surface for a long time . As a result , the tooth can be reliably bleached by maintaining the bleaching effect for a longer time than the ready-made product .
(3) The manufacturing method of the present invention does not require a fluidized bed or a mist-like hydrogen peroxide aqueous solution, which is indispensable in the conventional manufacturing method of granular bleaching agents, and does not use complicated equipment and equipment, so it maintains a certain quality. Tooth bleach can be manufactured at low cost and maintenance of the manufacturing plant is easy.
(4) Since the dry blend produced by the production method of the present invention is hard and brittle, it does not require a special instrument or apparatus to make a fine powder, and it is easy to produce a fine powder of a certain quality.

In the present invention, an edible polysaccharide is preferable from the viewpoint of safety as the polymer compound imparting the ability to generate active oxygen . The polysaccharides preferably used are karaya gum, gum arabic, guar gum, gellan gum and the like. Other edible polysaccharides may be used. A mixture of two or more of these can also be used.

Any substance capable of generating radical active oxygen when contacted with water molecules can be used as the substance that imparts active oxygen-generating ability to the polysaccharide . Examples include hydrogen peroxide, urea peroxide, perborate, percarbonate, perphosphate, persulfates, calcium peroxide, and magnesium peroxide. Preferably, it is hydrogen peroxide.

The polymer resin used to form a polysaccharide having an active oxygen generating capacity into a tooth bleaching attachment is an acrylic resin, polystyrene resin, methacrylic acid resin, vinyl chloride resin, vinyl acetate resin, epoxy, which is a dental resin. There are resins. Preferably, it is a methacrylic acid resin with little biological harm. A mixture of two or more of these can also be used.

An example of a method for imparting active oxygen generating ability to a polysaccharide is as follows. First, a polysaccharide and hydrogen peroxide solution are mixed at a ratio of 1 to 99%, finished to a uniform mixture, dried by natural drying or air drying, and finely powdered to produce a fine powdery tooth bleach. To do. The tooth bleaching agent thus produced retains bleaching ability for at least three months. Furthermore, if stored at −30 ° C. together with an oxygen scavenger in a sealed container, the bleaching ability is maintained for more than one year.

  The mixing ratio of the polysaccharide and the hydrogen peroxide solution is preferably 20 to 50% by weight, more preferably 30 to 35%. When mixed in a proportion exceeding this range, the operability is remarkably lowered, and it becomes difficult to impart the ability to generate active oxygen to the polysaccharide.

Even if the concentration of hydrogen peroxide is sufficiently lower than the concentration used conventionally, a tooth bleaching agent can be produced . That is, a tooth that exhibits almost the same bleaching ability regardless of whether it is a 35% hydrogen peroxide solution currently used for tooth bleaching or a 3% hydrogen peroxide solution used as a disinfectant. It is possible to produce bleach .

  In order to fix a tooth bleaching agent comprising a polysaccharide having an active oxygen generating ability on the surface of the tooth, a polymer resin is mixed with the tooth bleaching agent and shaped so as to conform to the tooth surface shape. The tooth bleaching mounting body thus molded is fixed and maintained on the tooth surface.

The present invention does not require a bleaching agent to be applied to teeth like a conventional tooth bleaching agent, and a polymer resin containing a polysaccharide having an active oxygen generating capacity is molded to match the tooth surface shape, Teeth can be bleached simply by adhering to the teeth.

  An embodiment of the present invention will be described below. First, one kind of edible polysaccharide is selected from karaya gum, gum arabic, guar gum, and gellan gum, and the selected polysaccharide is mixed with 35% hydrogen peroxide solution so as to be 35% by weight. Then, mix with great care to finish the mixture evenly. The mixture is allowed to stand at room temperature for 3 to 4 days and then air dried to remove moisture. Then, the dry blend is subjected to a pulverization process to produce a fine powder. The fine powdery tooth bleach thus obtained is sealed in a container and stored at minus 30 degrees.

  Next, a tooth bleaching mounting body is molded using the generated tooth bleaching agent and polymer resin. A fine powdery tooth bleach and a methacrylic acid resin polymer are mixed so that the ratio of the bleach to the mixture becomes 60% by weight, and then an appropriate amount of a methacrylic acid monomer solution is dropped into the mixed powder. Prior to curing, the mixed clay-like polymer is pressed against the tooth surface and formed into a shape suitable for the tooth surface shape.

In order to examine the bleaching effect of the tooth bleaching attachment according to this example, the following bleaching experiment was conducted.
(1) Bleaching experiment of tooth colored with basic fuchsin The extracted tooth was immersed in a 0.5% basic fuchsin solution for 24 hours and then left in running water for 48 hours to prepare a colored tooth. The tooth bleaching attachment produced according to the above method was brought into close contact with the tooth, and then left in a constant temperature bath at a humidity of 100% and 37 degrees. Then, photographs of teeth were taken over time, and the brightness was evaluated on a computer using a NIH image analyzer. At this time, the lightness of the tooth before dyeing was 100, the lightness of the tooth immediately after dyeing was 0, and the lightness of the tooth bleached by the tooth bleaching attachment was expressed as a relative value. The results are shown in Table 1.

(2) Bleaching test by patients with colored teeth For 20 patients who wished to bleach their teeth, how to use a mouthpiece combined with a tooth bleaching attachment produced according to the above method was explained at the dental clinic. After that, they were recorded in four levels, how long they felt whitening, and the comfort level during use, which was not uncomfortable, somewhat uncomfortable, uncomfortable, and uncomfortable tolerate.

  The usage time was calculated by integrating the time during which the mouthpiece was actually attached to the tooth. The time until home whitening (brand name: Matsukaze Highlight Shade-up, manufactured by Matsukaze Co., Ltd.), which is a known tooth bleaching method, is performed on 10 patients who wish to bleach their teeth as a control. And requested the evaluation of comfort during use. The results are shown in Table 2.

  The embodiments of the present invention are as described above, but it goes without saying that the technical idea of the present invention is not limited by the embodiments.

Claims (2)

A tooth bleaching agent having active oxygen-generating ability in the form of a fine powder composed of one or more polysaccharides selected from karaya gum, gum arabic, kua gum, and gellan gum . Mix one or more polysaccharides selected from karaya gum, gum arabic, kua gum, and gellan gum with a hydrogen peroxide solution having a concentration of 3 to 35% by weight in a proportion of 20 to 50% by weight to obtain a uniform state. A method for producing a tooth bleaching agent having the ability to generate active oxygen, which is dried by natural drying or air drying and then formed into a fine powder by a fine powder treatment .