JP4938855B2 - 健康管理のための時間生物学的リズムの監視 - Google Patents
健康管理のための時間生物学的リズムの監視 Download PDFInfo
- Publication number
- JP4938855B2 JP4938855B2 JP2009534573A JP2009534573A JP4938855B2 JP 4938855 B2 JP4938855 B2 JP 4938855B2 JP 2009534573 A JP2009534573 A JP 2009534573A JP 2009534573 A JP2009534573 A JP 2009534573A JP 4938855 B2 JP4938855 B2 JP 4938855B2
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- Prior art keywords
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- subject
- prediction
- circadian rhythm
- module
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- Expired - Fee Related
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/024—Measuring pulse rate or heart rate
- A61B5/02405—Determining heart rate variability
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
- A61B5/1116—Determining posture transitions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic using feedback of body parameters, e.g. blood sugar or pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/3614—Control systems using physiological parameters based on impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36585—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by two or more physical parameters
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/024—Measuring pulse rate or heart rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Signal Processing (AREA)
- Pulmonology (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Psychiatry (AREA)
- Artificial Intelligence (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/554,986 US7764996B2 (en) | 2006-10-31 | 2006-10-31 | Monitoring of chronobiological rhythms for disease and drug management using one or more implantable device |
| US11/554,986 | 2006-10-31 | ||
| PCT/US2007/020425 WO2008054580A2 (en) | 2006-10-31 | 2007-09-20 | Monitoring of chronobiological rhythms for health management |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010508065A JP2010508065A (ja) | 2010-03-18 |
| JP2010508065A5 JP2010508065A5 (enExample) | 2011-09-29 |
| JP4938855B2 true JP4938855B2 (ja) | 2012-05-23 |
Family
ID=39254002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534573A Expired - Fee Related JP4938855B2 (ja) | 2006-10-31 | 2007-09-20 | 健康管理のための時間生物学的リズムの監視 |
Country Status (4)
| Country | Link |
|---|---|
| US (5) | US7764996B2 (enExample) |
| EP (1) | EP2091421B1 (enExample) |
| JP (1) | JP4938855B2 (enExample) |
| WO (1) | WO2008054580A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8805493B2 (en) | 2006-10-31 | 2014-08-12 | Cardiac Pacemakers, Inc. | Monitoring of chronobiological rhythms for disease and drug management using one or more implantable device |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8396565B2 (en) | 2003-09-15 | 2013-03-12 | Medtronic, Inc. | Automatic therapy adjustments |
| US7433853B2 (en) * | 2004-07-12 | 2008-10-07 | Cardiac Pacemakers, Inc. | Expert system for patient medical information analysis |
| US8972002B2 (en) * | 2005-06-01 | 2015-03-03 | Cardiac Pacemakers, Inc. | Remote closed-loop titration of decongestive therapy for the treatment of advanced heart failure |
| US7957809B2 (en) | 2005-12-02 | 2011-06-07 | Medtronic, Inc. | Closed-loop therapy adjustment |
| US7662105B2 (en) | 2005-12-14 | 2010-02-16 | Cardiac Pacemakers, Inc. | Systems and methods for determining respiration metrics |
| CN105468895A (zh) | 2006-05-02 | 2016-04-06 | 普罗透斯数字保健公司 | 患者定制的治疗方案 |
| US8945005B2 (en) | 2006-10-25 | 2015-02-03 | Proteus Digital Health, Inc. | Controlled activation ingestible identifier |
| US7946995B1 (en) * | 2006-11-09 | 2011-05-24 | Pacesetter, Inc. | Analyzing circadian variations of a hemodynamic parameter to determine an adverse cardiac condition |
| EP2069004A4 (en) | 2006-11-20 | 2014-07-09 | Proteus Digital Health Inc | PERSONAL HEALTH SIGNAL RECEIVERS WITH ACTIVE SIGNAL PROCESSING |
| CA2676407A1 (en) | 2007-02-01 | 2008-08-07 | Proteus Biomedical, Inc. | Ingestible event marker systems |
| EP3236524A1 (en) | 2007-02-14 | 2017-10-25 | Proteus Digital Health, Inc. | In-body power source having high surface area electrode |
| US8052611B2 (en) | 2007-03-14 | 2011-11-08 | Cardiac Pacemakers, Inc. | Method and apparatus for management of heart failure hospitalization |
| DE102007014136B4 (de) * | 2007-03-23 | 2011-08-25 | Dr. Oestreich + Partner GmbH, 50670 | Vorrichtung zur medizinischen Versorgung eines Patienten in einem Notfall |
| US8115618B2 (en) | 2007-05-24 | 2012-02-14 | Proteus Biomedical, Inc. | RFID antenna for in-body device |
| DE102007043090A1 (de) * | 2007-09-10 | 2009-03-12 | Biotronik Crm Patent Ag | Fernprogrammierbares persönliches Gerät sowie Anordnung und Verfahren zum Fernprogrammieren eines persönlichen Gerätes |
| PT2192946T (pt) | 2007-09-25 | 2022-11-17 | Otsuka Pharma Co Ltd | Dispositivo no corpo com amplificação de sinal dipolo virtual |
| US9079033B2 (en) * | 2008-01-22 | 2015-07-14 | Cardiac Pacemakers, Inc. | Respiration as a trigger for therapy optimization |
| JP2011513865A (ja) | 2008-03-05 | 2011-04-28 | プロテウス バイオメディカル インコーポレイテッド | マルチモード通信の摂取可能なイベントマーカーおよびシステム、ならびにそれを使用する方法 |
| EP2265328B1 (en) * | 2008-03-20 | 2018-05-09 | EBS Technologies GmbH | An apparatus for automatic treatment adjustment after nervous system dysfunction |
| KR101615128B1 (ko) | 2008-07-08 | 2016-04-26 | 프로테우스 디지털 헬스, 인코포레이티드 | 섭취 가능한 이벤트 마커 데이터 프레임워크 |
| US8282580B2 (en) | 2008-07-11 | 2012-10-09 | Medtronic, Inc. | Data rejection for posture state analysis |
| US8708934B2 (en) | 2008-07-11 | 2014-04-29 | Medtronic, Inc. | Reorientation of patient posture states for posture-responsive therapy |
| US8688225B2 (en) | 2008-07-11 | 2014-04-01 | Medtronic, Inc. | Posture state detection using selectable system control parameters |
| US8504150B2 (en) | 2008-07-11 | 2013-08-06 | Medtronic, Inc. | Associating therapy adjustments with posture states using a stability timer |
| US8315710B2 (en) | 2008-07-11 | 2012-11-20 | Medtronic, Inc. | Associating therapy adjustments with patient posture states |
| US9050471B2 (en) | 2008-07-11 | 2015-06-09 | Medtronic, Inc. | Posture state display on medical device user interface |
| US9440084B2 (en) | 2008-07-11 | 2016-09-13 | Medtronic, Inc. | Programming posture responsive therapy |
| US8644945B2 (en) | 2008-07-11 | 2014-02-04 | Medtronic, Inc. | Patient interaction with posture-responsive therapy |
| US8437861B2 (en) | 2008-07-11 | 2013-05-07 | Medtronic, Inc. | Posture state redefinition based on posture data and therapy adjustments |
| US9713701B2 (en) | 2008-07-31 | 2017-07-25 | Medtronic, Inc. | Using multiple diagnostic parameters for predicting heart failure events |
| US8280517B2 (en) * | 2008-09-19 | 2012-10-02 | Medtronic, Inc. | Automatic validation techniques for validating operation of medical devices |
| JP2012514799A (ja) | 2009-01-06 | 2012-06-28 | プロテウス バイオメディカル インコーポレイテッド | 摂取に関連するバイオフィードバックおよび個別薬物療法の方法およびシステム |
| US9327070B2 (en) * | 2009-04-30 | 2016-05-03 | Medtronic, Inc. | Medical device therapy based on posture and timing |
| US8175720B2 (en) | 2009-04-30 | 2012-05-08 | Medtronic, Inc. | Posture-responsive therapy control based on patient input |
| US8231555B2 (en) | 2009-04-30 | 2012-07-31 | Medtronic, Inc. | Therapy system including multiple posture sensors |
| US20110009760A1 (en) * | 2009-07-10 | 2011-01-13 | Yi Zhang | Hospital Readmission Alert for Heart Failure Patients |
| US20110009753A1 (en) * | 2009-07-10 | 2011-01-13 | Yi Zhang | Respiration Rate Trending for Detecting Early Onset of Worsening Heart Failure |
| US8758323B2 (en) | 2009-07-30 | 2014-06-24 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| JP5243375B2 (ja) * | 2009-09-09 | 2013-07-24 | 日本光電工業株式会社 | 生体信号処理装置及び医療装置制御方法 |
| US8900140B2 (en) | 2009-10-27 | 2014-12-02 | Cardiac Pacemakers, Inc. | Multiple vector fluid localization |
| TWI517050B (zh) | 2009-11-04 | 2016-01-11 | 普羅托斯數位健康公司 | 供應鏈管理之系統 |
| US8758274B2 (en) | 2010-01-08 | 2014-06-24 | Medtronic, Inc. | Automated adjustment of posture state definitions for a medical device |
| US9357949B2 (en) | 2010-01-08 | 2016-06-07 | Medtronic, Inc. | User interface that displays medical therapy and posture data |
| US8579834B2 (en) | 2010-01-08 | 2013-11-12 | Medtronic, Inc. | Display of detected patient posture state |
| US9956418B2 (en) | 2010-01-08 | 2018-05-01 | Medtronic, Inc. | Graphical manipulation of posture zones for posture-responsive therapy |
| US20110230771A1 (en) * | 2010-03-19 | 2011-09-22 | Pacesetter, Inc. | Heart failure status monitoring |
| US10238362B2 (en) * | 2010-04-26 | 2019-03-26 | Gary And Mary West Health Institute | Integrated wearable device for detection of fetal heart rate and material uterine contractions with wireless communication capability |
| US9566441B2 (en) | 2010-04-30 | 2017-02-14 | Medtronic, Inc. | Detecting posture sensor signal shift or drift in medical devices |
| TWI557672B (zh) | 2010-05-19 | 2016-11-11 | 波提亞斯數位康健公司 | 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置 |
| US9532423B2 (en) | 2010-07-23 | 2016-12-27 | Lighting Science Group Corporation | System and methods for operating a lighting device |
| US9827439B2 (en) * | 2010-07-23 | 2017-11-28 | Biological Illumination, Llc | System for dynamically adjusting circadian rhythm responsive to scheduled events and associated methods |
| KR101805078B1 (ko) * | 2010-08-13 | 2018-01-10 | 레스퍼러토리 모션 인코포레이티드 | 호흡량, 운동 및 가변성 측정에 의한 호흡 변화 모니터링 장치 및 방법 |
| US12383190B2 (en) | 2011-03-04 | 2025-08-12 | Flint Hills Scientific, Llc | Detecting, assessing and managing extreme seizure events |
| US9717412B2 (en) | 2010-11-05 | 2017-08-01 | Gary And Mary West Health Institute | Wireless fetal monitoring system |
| US9420959B2 (en) | 2010-12-15 | 2016-08-23 | Cardiac Pacemakers, Inc. | Detecting heart failure by monitoring the time sequence of physiological changes |
| AU2011344004B2 (en) | 2010-12-15 | 2014-12-04 | Cardiac Pacemakers, Inc. | Cardiac decompensation detection using multiple sensors |
| AU2011344010B2 (en) | 2010-12-15 | 2014-12-18 | Cardiac Pacemakers, Inc. | Posture detection using thoracic impedance |
| US20120157793A1 (en) * | 2010-12-20 | 2012-06-21 | General Electric Company | Medication intake analyzer |
| WO2012092057A1 (en) * | 2010-12-29 | 2012-07-05 | Ethicon Endo-Surgery, Inc. | Methods and devices for activating brown adipose tissue with light |
| US8478403B2 (en) | 2011-02-23 | 2013-07-02 | Pacesetter, Inc. | Implantable systems and methods for use therewith for monitoring and modifying arterial blood pressure without requiring an intravascular pressure transducer |
| US9504390B2 (en) | 2011-03-04 | 2016-11-29 | Globalfoundries Inc. | Detecting, assessing and managing a risk of death in epilepsy |
| FR2973049B1 (fr) | 2011-03-21 | 2016-12-23 | Arjowiggins Security | Support d'information ou papier comportant un materiau auto-reparant |
| FR2975408B1 (fr) | 2011-05-18 | 2020-10-23 | Arjowiggins Security | Feuille a haute durabilite pour la fabrication de billets de banque |
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| US8805493B2 (en) | 2006-10-31 | 2014-08-12 | Cardiac Pacemakers, Inc. | Monitoring of chronobiological rhythms for disease and drug management using one or more implantable device |
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| JP2010508065A (ja) | 2010-03-18 |
| US8805493B2 (en) | 2014-08-12 |
| EP2091421A2 (en) | 2009-08-26 |
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| US20130289476A1 (en) | 2013-10-31 |
| WO2008054580A2 (en) | 2008-05-08 |
| EP2091421B1 (en) | 2016-04-13 |
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